研究者詳細 - 牧迫　飛雄馬

論文 - 牧迫　飛雄馬

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鈴木隆雄, 鄭丞媛, 西田裕紀子, 大塚礼, 島田裕之, 牧迫飛雄馬, 金憲経, 大渕修一, 河合恒, 藤原佳典, 阿部巧, 小島成実, 平野浩彦, 増井幸恵, 稲垣宏樹, 吉田祐子, 飯島勝矢, 吉村典子, 山田実, 渡辺修一郎, 近藤克則, 村木功, 岩佐一 . 地域在宅高齢者における高次生活機能について . 応用老年学18 ( 1 ) 107 - 116 2024年

記述言語：日本語出版者・発行元：一般社団法人日本応用老年学会

<p>　日本は急速な超高齢社会を迎え，平均寿命の著しい伸びとともに，高齢者の生活機能も大きく変容し，健康水準の高い活力ある高齢者が増加している．</p><p>　本研究では，我が国の地域在宅高齢者を対象とした老化に関する多数のコホート研究の統合研究（「長寿コホートの統合的研究；Integrated Longitudinal Study on Aging in Japan: ILSA-J」）で収集された高次生活機能評価指標であるJST版活動能力指標（JST-IC）を用いて，現代の地域在宅高齢者における生活活動能力の現状を報告した．JST-ICでは総合スコアおよび４項目の下位尺度（新機器利用，情報収集，生活マネジメント，社会参加）について性別および年齢階級別の平均値と標準偏差を算出した．その結果，男女間では情報収集以外の全ての項目で性差が認められ，年齢階級間では男女ともに全ての項目で有意差が認められ，加齢に伴いスコアは低下していた．本研究では，高齢者の高次生活機能の一端を明らかにし，今後の利活用に資する資料とした．</p>

DOI： 10.60455/sagj.18.1_107

CiNii Research

Makino K., Raina P., Griffith L.E., Lee S., Harada K., Chiba I., Katayama O., Tomida K., Morikawa M., Makizako H., Shimada H. . Physical frailty and survival time after the onset of functional disability: Is there a sex difference? . Journal of the American Geriatrics Society72 ( 2 ) 399 - 409 2023年12月国際誌

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Journal of the American Geriatrics Society

Background: Physical frailty accelerates the timing of both subsequent disability and death; however, evidence regarding the impact of frailty on the period from disability onset to death and sex differences of this impact is lacking. The aim of this study was to examine the relationship among physical frailty, disability, death, and sex differences. Methods: This Japanese cohort study included 10,524 community-dwelling people aged ≥65 years. Physical frailty was operationalized by key phenotypes as per Fried's criteria (slowness, weakness, exhaustion, weight loss, and low activity) at baseline. We calculated hazard ratios (HRs) with 95% confidence intervals (CIs) for disability onset and post-disability survival according to the frailty status. Results: During a 5-year follow-up, the risk of disability onset for pre-frailty (HR: 1.74, 95% CI: 1.51–2.00) and frailty (HR: 3.27, 95% CI: 2.77–3.87) were significantly higher than that for robust people. Furthermore, among participants who developed disabilities within 5 years (n = 1481), the risk of post-disability death for pre-frailty was not different from that for robust (HR: 1.49, 95% CI: 0.99–2.24), but frailty showed a higher risk of post-disability death than did robust people. (HR: 1.75, 95% CI: 1.13–2.72). In the sex-stratified analysis, although the female group showed no association between frailty status and post-disability death (HR: 1.21, 95% CI: 0.63–2.33 in pre-frailty; HR: 1.24, 95% CI: 0.60–2.57 in frailty), the male group showed higher risk of post-disability death in both pre-frailty (HR: 1.74, 95% CI: 1.03–2.96) and frailty (HR: 2.32, 95% CI: 1.32–4.09). Conclusions: Physical frailty shortens the period from disability onset to death. Additionally, the impact of frailty on post-disability death is greater for males than for females. Our findings suggest that physical frailty is an important clinical indicator distinct from disability and that interventions to prevent and address frailty in men need further investigation.

DOI： 10.1111/jgs.18725

Scopus

PubMed

Kiuchi Y., Doi T., Tsutsumimoto K., Nakakubo S., Kurita S., Nishimoto K., Makizako H., Shimada H. . Association between dietary diversity and cognitive impairment in community-dwelling older adults . Geriatrics and Gerontology International24 ( 1 ) 75 - 81 2023年12月

記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：Geriatrics and Gerontology International

Aim: The present study aimed to examine whether dietary diversity is associated with cognitive impairment, including mild cognitive impairment (MCI), in community-dwelling older Japanese adults. Methods: This cross-sectional study was carried out in a general community setting. MCI and global cognitive impairment (GCI) were assessed using the Mini-Mental State Examination and National Center for Geriatrics and Gerontology-Functional Assessment Tool, which are multicomponent neurocognitive tests that include memory attention, executive function and processing speed. Dietary diversity was assessed using the diet variety score. The diet variety score assessed the 1-week consumption frequency of 10 food groups, and either 0 or 1 point was allocated to each category based on the following responses: (i) “eat almost every day” (1 point); and (ii) “not eaten almost daily” (0 points). Older adults with a diet variety score of ≥3 points were defined as having high dietary diversity. Results: Data included 8987 older adults (mean age 73.9 ± 5.5 years; men 44.3%). The overall prevalences of MCI and GCI were 17.1% (n = 1538) and 8.4% (n = 753), respectively. The proportion of patients with a high dietary diversity was 69.9% (n = 6286). Multinomial logistic regression analysis revealed high dietary diversity was associated with MCI (OR 0.83, 95% CI 0.73–0.94) and GCI (OR 0.77, 95% CI 0.65–0.92) after adjusting for covariates. Conclusions: This study had a large sample size of older Japanese adults, and showed that high dietary diversity was associated with a lower proportion of MCI and GCI among older adults. Geriatr Gerontol Int 2024; 24: 75–81.

DOI： 10.1111/ggi.14762

Scopus

PubMed

Kiuchi Y., Tsutsumimoto K., Doi T., Kurita S., Nishimoto K., Makizako H., Shimada H. . Effect of dietary diversity on incident of disability in community-dwelling older adults with sarcopenia: A 40-month follow-up longitudinal study . Maturitas179 107887 - 107887 2023年11月国際誌

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Maturitas

Background: Sarcopenia is a clinical issue in older adults that leads to serious adverse health outcomes, including disability. The present study investigated whether dietary diversity affects the incidence of disability in older adults with sarcopenia. Method: Participants were 759 Japanese older adults with sarcopenia (mean age 77.2 ± 6.0 years; 44.4 % men) who were aged ≥65 years at the time of the examination. Sarcopenia was diagnosed according to the recommendations of the European Working Group on Sarcopenia in Older People 2. Dietary diversity was assessed using a diet variety score. This diet variety score assessed the one-week consumption frequency of ten food groups, according to the following responses: “eat almost every day” (1 point), or “not eaten almost daily” (0 points). Older adults with a diet variety score of 3 or more points were defined as having high dietary diversity. Incident disability was certified by long-term care insurance (mean follow-up duration 32 months). Results: The cumulative disability incidence rates in the older adults with low dietary diversity and high dietary diversity were 23.3 % and 16.9 %, respectively. Cox proportional hazards regression analysis revealed high dietary diversity was associated with a lower risk of incident disability in older adults with sarcopenia (hazard ratio 0.66, 95 % confidence interval 0.47–0.92; p = 0.015), after adjusting for covariates. Conclusions: This longitudinal study revealed that high dietary diversity is associated with a lower risk of incident disability among sarcopenic Japanese older adults.

DOI： 10.1016/j.maturitas.2023.107887

Scopus

PubMed

赤井田将真, 白土大成, 木内悠人, 立石麻奈, 牧迫飛雄馬 . 地域在住高齢女性における自動車運転の経験と認知機能の関連 . 日本作業療法学会抄録集57回 ON - 6 2023年11月

Shiratsuchi D., Makizako H., Tateishi M., Akaida S., Tagata C., Kobayashi M., Takihara T. . Association between muscle weakness and cap-grasping patterns when opening plastic bottles in community-dwelling older adults . Geriatrics and Gerontology International23 ( 10 ) 758 - 760 2023年10月

立石麻奈, 赤井田将真, 桑原祐一, 牧迫飛雄馬 . フレイル高齢者における運動教室が社会交流および運動習慣構築の促進につながった事例 . 日本老年医学会雑誌60 ( 4 ) 482 - 482 2023年10月

赤井田将真, 立石麻奈, 谷口善昭, 木内悠人, 福榮竜也, 白土大成, 愛下由香里, 窪薗琢郎, 大石充, 牧迫飛雄馬 . 自動車運転をしていない地域在住後期高齢女性における免許保有歴と認知機能の関連 . 日本老年医学会雑誌60 ( 4 ) 483 - 483 2023年10月

牧迫飛雄馬 . こころのゆとり . 日本予防理学療法学会雑誌3 ( 1 ) 1 - 1 2023年9月

牧迫飛雄馬 . 特集によせて . 日本サルコペニア・フレイル学会誌7 ( 1 ) 4 - 4 2023年6月

Araki S., Kiyama R., Nakai Y., Kawada M., Miyazaki T., Takeshita Y., Makizako H. . Sex differences in age-related differences in joint motion during gait in community-dwelling middle-age and older individuals . Gait and Posture103 153 - 158 2023年6月国際誌

記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：Gait and Posture

Background: Walking is the most important mode of human locomotion; however, the ability to walk often decreases with age. Age-related differences in lower-limb kinematics during gait may differ depending on sex. However, the question of the compounded effects of age and sex on gait kinematics remains unsolved. Research question: The present study aimed to clarify the interaction between age and sex in differences in gait kinematics of community-dwelling middle-age and older individuals. Methods: This study included 836 community-dwelling middle-age and older adults (61.8 % female). Joint motion during comfortable gait was measured using magnetic and inertial measurement units. Hip, knee, and ankle joint angles were calculated in the sagittal plane. Participants were divided into four groups according to age: 50–59, 60–69, 70–79, and 80–89 years. The interaction of sex and age on spatiotemporal gait parameters and the peak value of joint angles was analyzed using two-way analysis of variance (ANOVA) and Tukey's post hoc test. Results: Gait speed (F = 43.92, P < 0.001), step length (F = 73.00, P < 0.001), hip extension (F = 12.89, P = 0.002), knee flexion (F = 39.99, P < 0.001), and ankle plantar flexion (F = 27.43, P < 0.001) significantly decreased with age. Significant differences according to sex were observed in all parameters except gait speed. Significant age and sex interaction effects were observed for knee flexion (F = 4.97, P = 0.002) and ankle dorsiflexion (F = 4.04, P = 0.007). Significance: A significant interaction effect of age and sex was observed for peak angle of knee flexion and ankle dorsiflexion during gait. In particular, the knee flexion angle among females during gait began to decrease from 60 years of age, and the decreasing trend was faster and more prominent than that among males.

DOI： 10.1016/j.gaitpost.2023.05.009

Scopus

PubMed

Muto K., Shiratsuchi D., Nanbu K., Sakamoto H., Furuya N., Nakamura K., Yushi M., Tsujita N., Makizako H. . Ability to walk 10 m within the first week of stroke predicts independent outdoor walking and destination . Journal of Stroke and Cerebrovascular Diseases32 ( 8 ) 107145 - 107145 2023年5月国際誌

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Journal of Stroke and Cerebrovascular Diseases

Objectives: We aimed to determine if achieving a 10-m walk target within the first week of stroke onset correlates with independent outdoor walking at discharge and discharge to home for patients with stroke. Materials and methods: This study included 226 patients transferred to the subacute rehabilitation hospital (SRH) between January 2018 and March 2021. Data obtained from hospital records included age, sex, stroke type, lesion side, body mass index, presence of acute treatment, length of days from onset to physical therapy intervention, National Institutes of Health Stroke Scale, length of hospital stay, Functional Independence Measure score, and the ability to complete the 10 m walk target within the first week of stroke onset. The primary outcomes were independent outdoor walking ability and discharge destination from the SRH. A logistic regression analysis was performed to determine if the 10 m walking ability correlated with the outdoor walking ability and discharge destination. Results: Compared with the inability to walk 10 m, walking 10 m independently walking within the first week of stroke onset correlated with the ability to walk independently outdoors at discharge (odds ratio [OR]: 4.38, p = 0.003) and being discharged home (OR: 4.52, p = 0.002), whereas, walking 10 m with assistance was associated with being discharged home (OR: 3.09, p = 0.043). Conclusions: The ability to walk 10 m within the first week of stroke onset may be a helpful marker for prognosis.

DOI： 10.1016/j.jstrokecerebrovasdis.2023.107145

Scopus

PubMed

鈴木隆雄, 西田裕紀子, 牧迫飛雄馬, 鄭丞媛, 島田裕之, 大塚礼, 阿部巧 . 地域在住高齢者の健康関連変数の2007年から2017年の推移長寿コホートの総合的研究(ILSA-J) . 日本老年医学会雑誌60 ( Suppl. ) 177 - 178 2023年5月

大塚礼, 西田裕紀子, 牧迫飛雄馬, 鄭丞媛, 阿部巧, 島田裕之, 鈴木隆雄, 藤原佳典, 大渕修一, 鈴木宏幸, 岩崎正則, 小島成実, 飯島勝矢, 吉村典子, 渡辺修一郎, 山田実, 村木功, 近藤克則, 新村健 . 地域在住高齢者のサルコペニア頻度の2012年から2017年の推移長寿コホートの総合的研究(ILSA-J) . 日本老年医学会雑誌60 ( Suppl. ) 49 - 50 2023年5月

白土大成, 谷口善昭, 赤井田将真, 立石麻奈, 木内悠人, 愛下由香里, 福榮竜也, 倉津諒大, 牧迫飛雄馬 . 地域在住高齢者におけるペットボトル開栓時のキャップ把持パターンと筋力低下の関連性 . 日本老年医学会雑誌60 ( Suppl. ) 177 - 177 2023年5月

倉津諒大, 谷口善昭, 木内悠人, 赤井田将真, 白土大成, 立石麻奈, 福榮竜也, 愛下由香里, 牧迫飛雄馬 . 地域在住高齢者におけるMotoric cognitive risk syndromeと転倒恐怖感との関連 . 日本老年医学会雑誌60 ( Suppl. ) 158 - 159 2023年5月

赤井田将真, 立石麻奈, 谷口善昭, 白土大成, 木内悠人, 窪薗琢郎, 大石充, 牧迫飛雄馬 . 地域在住中高齢者の自動車運転実施状況および生活活動と身体機能,筋量との関連 . 日本老年医学会雑誌60 ( Suppl. ) 136 - 136 2023年5月

牧迫飛雄馬, 赤井田将真, 立石麻奈, 白土大成, 谷口善昭, 竹中俊宏, 窪薗琢郎, 大石充 . α-アクチニン3遺伝子多型が身体機能の加齢変化に及ぼす影響 3年間の縦断観察研究 . 日本老年医学会雑誌60 ( Suppl. ) 145 - 146 2023年5月

Hidaka Yuma, Tabira Takayuki, Maruta Michio, Makizako Hyuma, Ikeda Yuriko, Nakamura Atsushi, Han Gwanghee, Miyata Hironori, Shimokihara Suguru, Akasaki Yoshihiko, Kamasaki Taishiro, Kubozono Takuro, Ohishi Mitsuru . Relationship between grave visitation and apathy among community-dwelling older adults(タイトル和訳中) . Psychogeriatrics23 ( 3 ) 401 - 410 2023年5月

記述言語：英語出版者・発行元：John Wiley & Sons Australia, Ltd

垂水研究に参加した高齢者を対象として、墓参りと抑うつ症状およびアパシーとの関連を調べた。評価項目は高齢者うつ尺度、墓参りに関する項目(墓参りの有無、頻度、移動時間、移動手段、供花)などとした。高齢者を墓参状況により、頻繁群240名(週1回以上、平均74.9±6.4歳、女性170名)、不定期群346名(週1回未満、平均73.8±6.4歳、女性195名)、非墓参群52名(墓参せず、平均74.6±7.1歳、女性32名)に分けて検討した。その結果、非墓参群は墓参群と比較して、アパシー有病率が有意に高かった。潜在的共変量調整後のポアソン回帰分析の結果、非墓参群はアパシーと有意に関連していた。以上のように、高齢者において墓参りをしないこととアパシーには有意な関連があることが示された。

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