研究者詳細 - 牧迫　飛雄馬

論文 - 牧迫　飛雄馬

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宮崎宣丞, 竹下康文, 中井雄貴, 荒木草太, 川田将之, 木山良二, 牧迫飛雄馬 . 地域在住高齢女性における歩行速度増大の戦略と歩行パラメータ,身体機能の関連 . 基礎理学療法学26 ( Suppl.1 ) 117 - 117 2024年1月

Kiuchi Yuto, Doi Takehiko, Tsutsumimoto Kota, Nakakubo Sho, Kurita Satoshi, Nishimoto Kazuhei, Makizako Hyuma, Shimada Hiroyuki . Association between dietary diversity and cognitive impairment in community-dwelling older adults(タイトル和訳中) . Geriatrics & Gerontology International24 ( 1 ) 75 - 81 2024年1月

記述言語：英語出版者・発行元：John Wiley & Sons Australia, Ltd

地域在住高齢者における摂取食品の多様性と認知機能との関連を検討するため、横断研究を実施した。2017年から2018年までの日本人高齢者8,987例(男性44.3%、平均73.9歳)を評価対象とした。ミニメンタルステート検査を用いて軽度認知障害(MCI)と全般的な認知機能低下(GCI)を評価したところ、MCIを17.1%(1538例)、GCIを8.4%(753例)に認めた。多変量ロジスティック回帰分析の結果、食品摂取多様性のある高齢者では、MCI、GCIのリスクが有意に低かった。

Akaida S., Shiratsuchi D., Tateishi M., Kuratsu R., Makizako H. . Life satisfaction and awareness of meaningful activities among middle-aged adults: A population-based study . British Journal of Occupational Therapy87 ( 9 ) 556 - 563 2024年

記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：British Journal of Occupational Therapy

Introduction: Meaningful activities have been suggested to contribute to life satisfaction. Investigating the association between the awareness of meaningful activities and life satisfaction will help us develop a population-based occupational therapy strategy. The purpose of this study was to investigate the proportion of people who were aware of meaningful activities among middle-aged adults, and the relationship between the awareness of meaningful activities and life satisfaction. Method: A cross-sectional analysis was conducted on 2698 middle-aged adults who participated in an online survey conducted in Japan by the Y-Cloud system. Participants responded to demographic questions, life satisfaction, and awareness of meaningful activities. We examined the association between the awareness of meaningful activities and life satisfaction using binomial logistic regression analysis. Results: Of the respondents, 77.4% were aware of meaningful activities. Binomial logistic regression analysis adjusted for covariates showed that the awareness of meaningful activities was significantly associated with higher life satisfaction (odds ratio, 2.97; 95% confidence interval: 2.45–3.61, p < 0.001). Conclusion: The results suggest the value of presenting that the awareness of meaningful activities should be considered in preventive population-based occupational therapy strategies for life satisfaction.

DOI： 10.1177/03080226241253110

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その他リンク： https://journals.sagepub.com/doi/full-xml/10.1177/03080226241253110

Otsuka S., Kikuchi K., Takeshita Y., Takada S., Tani A., Sakakima H., Maruyama I., Makizako H. . Relationship between physical activity and cerebral white matter hyperintensity volumes in older adults with depressive symptoms and mild memory impairment: a cross-sectional study . Frontiers in Aging Neuroscience16 1337397 2024年

記述言語：日本語出版者・発行元：Frontiers in Aging Neuroscience

Introduction: Cerebral white matter hyperintensities (WMHs) are commonly found in the aging brain and have been implicated in the initiation and severity of many central nervous system diseases. Furthermore, an increased WMH volume indicates reduced brain health in older adults. This study investigated the association between WMH volume and physical activity in older adults with depressive symptoms (DS) and mild memory impairment (MMI). Factors associated with the WMH volume were also investigated. Methods: A total of 57 individuals aged over 65 years with DS and MMI were included in this study. The participants underwent magnetic resonance imaging to quantify WMH volumes. After WMH volume was accumulated, normalized to the total intracranial volume (TIV), the percentage of WMH volume was calculated. In addition, all participants wore a triaxial accelerometer for 2 weeks, and the average daily physical activity and number of steps were measured. The levels of blood biomarkers including cortisol, interleukin-6 (IL-6), brain-derived insulin-like growth factor-1, and brain-derived neurotrophic factor were measured. Motor and cognitive functions were also assessed. Results: Faster maximum walking speed and longer time spent engaged in moderate physical activity were associated with a smaller percent of WMH volume, whereas higher serum IL-6 levels were associated with a larger percent of WMH volume. The number of steps per day, time spent engaged in low levels of physical activity, cognitive function, and all other measured biomarkers were not significantly associated with percent of WMH volume. Discussion: Higher blood inflammatory cytokine levels, shorter duration of moderate physical activity, and lower maximum walking speed were associated with a higher percent of WMH volume. Our results provide useful information for maintaining brain health in older adults at a high risk of developing dementia and may contribute to the development of preventive medicine for brain health.

DOI： 10.3389/fnagi.2024.1337397

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Shimokihara S., Tabira T., Maruta M., Makizako H., Han G., Ikeda Y., Kamasaki T., Akasaki Y., Hidaka Y., Kumura Y., Kukizaki W., Nakahara R., Matsunaga S., Medina L., Kubozono T., Ohishi M. . Smartphone Proficiency in Community-Dwelling Older Adults is Associated With Higher-Level Competence and Physical Function: A Population-Based Age-Specific Cross-Sectional Study . Journal of Applied Gerontology44 ( 1 ) 7334648241261885 - 61 2024年

記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：Journal of Applied Gerontology

With the rapid development of information and communication technology, smartphone ownership has increased among older adults. While previous research has examined the impact of smartphone use on the health of older adults, this study focuses on the less-explored relationship between smartphone use, proficiency, and health-related outcomes including higher-level competence. The study was a cross-sectional survey of 208 community-dwelling older adults who used smartphones daily. Smartphone use, including years of use and applications, was assessed and categorized by age group. Health-related outcomes were measured, including cognitive and psychological function, higher-level competence, basic daily abilities, and physical function. The results indicated that smartphone proficiency decreased with age, with older adults primarily using basic smartphone applications. Notably, higher smartphone proficiency was positively associated with higher-level competence and physical functions. The study underscores the importance of considering smartphone proficiency when assessing older adults’ life skills and physical performance in our digital society.

DOI： 10.1177/07334648241261885

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PubMed

その他リンク： https://journals.sagepub.com/doi/full-xml/10.1177/07334648241261885

Akaida S., Makizako H., Tateishi M., Shiratsuchi D., Taniguchi Y., Kiuchi Y., Kiyama R., Takenaka T., Kubozono T., Ohishi M. . Importance of Lifestyle Activities for Older Adults’ Psychosomatic Functions After Driving Cessation: Interpretation by a Mixed-Methods Study . Journal of Applied Gerontology44 ( 4 ) 7334648241277043 - 541 2024年

記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：Journal of Applied Gerontology

Older adults who cease driving are more likely to experience psychosomatic decline than those who continue driving. This mixed-methods study was intended to examine differences in psychosomatic functions depending on driving status and lifestyle activities, and factors affecting engagement in additional lifestyle activities after driving cessation. The quantitative analysis included individuals aged 60 and above. Driving status, lifestyle activities, and psychosomatic functions were assessed. For qualitative analysis, semi-structured interviews were conducted with the driving-cessation group to determine the factors affecting involvement in various lifestyle activities after driving cessation. Analysis of covariance was used for quantitative data, while text mining and qualitative inductive analysis were used for qualitative data. Older adults who engaged in more lifestyle activities walked faster than those who engaged in fewer lifestyle activities, even after driving cessation. Actively using local and personal resources may increase engagement in lifestyle activities after driving cessation.

DOI： 10.1177/07334648241277043

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その他リンク： https://journals.sagepub.com/doi/full-xml/10.1177/07334648241277043

Akaida S., Tabira T., Tateishi M., Shiratsuchi D., Shimokihara S., Kuratsu R., Akasaki Y., Hidaka Y., Makizako H. . Averting older adults' memory function decline via meaningful activities: a follow-up longitudinal study . European Geriatric Medicine15 ( 6 ) 1793 - 1801 2024年

記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：European Geriatric Medicine

Purpose: The purpose of the study was to investigate the effects of satisfaction with meaningful activities and their performance on the memory function among community-dwelling older adults 3 years later. Methods: A longitudinal analysis was conducted on 288 community-dwelling older adults aged 65 years and more who had completed the survey in 2019 and 2022 as participants in the Tarumizu Study. Meaningful activities were assessed in 2019 using the Aid for Decision-Making in Occupation Choice for activities. Satisfaction with and performance of meaningful activities were assessed, and the bottom 25% were classified into two groups: low satisfaction and low performance. Memory function was assessed using the National Center for Geriatrics and Gerontology-Functional Assessment Tool in 2019 and 2022. Changes in memory function over 3 years were analyzed by satisfaction and performance of meaningful activities. Results: Two-way analysis of variance with group (satisfaction with and performance of meaningful activities) and time (2019 and 2022) as factors showed no statistically significant group-time interaction for memory in the satisfaction with meaningful activities group (F = 1.4, p = 0.24). Meanwhile, a statistically significant group-time interaction was observed for memory in the meaningful activity performance group, indicating that high performance of meaningful activities may play a protective role against memory decline (F = 7.4, p = 0.007). Conclusion: Higher performance of meaningful activities may protect against age-related changes in memory. A careful assessment of meaningful activities, and engagement that enhances performance may be useful in designing health support against memory decline.

DOI： 10.1007/s41999-024-01044-4

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その他リンク： https://link.springer.com/article/10.1007/s41999-024-01044-4/fulltext.html

古谷直弘, 四宮明宏, 白土大成, 土方麻衣, 坂本勇斗, 武藤健人, 牧迫飛雄馬 . 胃癌・大腸癌患者における術前のPossible Sarcopeniaと術後の合併症および在院日数との関連 . 日本がん・リンパ浮腫理学療法学会誌advpub ( 0 ) 39 - 47 2024年

記述言語：日本語出版者・発行元：一般社団法人日本がん・リンパ浮腫理学療法学会

【目的】本研究の目的は、胃癌または大腸癌を有する患者の術前のPossible Sarcopenia（PS）と握力の低下、5回椅子起立時間の延長と術後の合併症の発生および在院日数との関連を検討することとした。 【方法】対象は、胃癌または大腸癌の術後に自宅退院した患者75例とした。Asian Working Group for Sarcopenia 2019に準じて術前のPS、握力の低下、5回椅子起立時間の延長を判定し、術後の合併症の発生と在院日数との関連を調査した。 【結果】術前のPSは、術後の合併症の発生と在院日数の長期化との関連が認められた。握力の低下、5回椅子起立時間の延長は、術後の合併症の発生と在院日数の長期化との関連が認められなかった。 【結論】術前のPSは、胃癌または大腸癌を有する患者の術後の合併症の発生と在院日数の長期化との関連が示唆された。

DOI： 10.60366/jjptol.jjptol-r5-a11

CiNii Research

鈴木隆雄, 鄭丞媛, 西田裕紀子, 大塚礼, 島田裕之, 牧迫飛雄馬, 金憲経, 大渕修一, 河合恒, 藤原佳典, 阿部巧, 小島成実, 平野浩彦, 増井幸恵, 稲垣宏樹, 吉田祐子, 飯島勝矢, 吉村典子, 山田実, 渡辺修一郎, 近藤克則, 村木功, 岩佐一 . 地域在宅高齢者における高次生活機能について . 応用老年学18 ( 1 ) 107 - 116 2024年

記述言語：日本語出版者・発行元：一般社団法人日本応用老年学会

日本は急速な超高齢社会を迎え，平均寿命の著しい伸びとともに，高齢者の生活機能も大きく変容し，健康水準の高い活力ある高齢者が増加している．　本研究では，我が国の地域在宅高齢者を対象とした老化に関する多数のコホート研究の統合研究（「長寿コホートの統合的研究；Integrated Longitudinal Study on Aging in Japan: ILSA-J」）で収集された高次生活機能評価指標であるJST版活動能力指標（JST-IC）を用いて，現代の地域在宅高齢者における生活活動能力の現状を報告した．JST-ICでは総合スコアおよび４項目の下位尺度（新機器利用，情報収集，生活マネジメント，社会参加）について性別および年齢階級別の平均値と標準偏差を算出した．その結果，男女間では情報収集以外の全ての項目で性差が認められ，年齢階級間では男女ともに全ての項目で有意差が認められ，加齢に伴いスコアは低下していた．本研究では，高齢者の高次生活機能の一端を明らかにし，今後の利活用に資する資料とした．

DOI： 10.60455/sagj.18.1_107

CiNii Research

Makino K., Raina P., Griffith L.E., Lee S., Harada K., Chiba I., Katayama O., Tomida K., Morikawa M., Makizako H., Shimada H. . Physical frailty and survival time after the onset of functional disability: Is there a sex difference? . Journal of the American Geriatrics Society72 ( 2 ) 399 - 409 2023年12月国際誌

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Journal of the American Geriatrics Society

Background: Physical frailty accelerates the timing of both subsequent disability and death; however, evidence regarding the impact of frailty on the period from disability onset to death and sex differences of this impact is lacking. The aim of this study was to examine the relationship among physical frailty, disability, death, and sex differences. Methods: This Japanese cohort study included 10,524 community-dwelling people aged ≥65 years. Physical frailty was operationalized by key phenotypes as per Fried's criteria (slowness, weakness, exhaustion, weight loss, and low activity) at baseline. We calculated hazard ratios (HRs) with 95% confidence intervals (CIs) for disability onset and post-disability survival according to the frailty status. Results: During a 5-year follow-up, the risk of disability onset for pre-frailty (HR: 1.74, 95% CI: 1.51–2.00) and frailty (HR: 3.27, 95% CI: 2.77–3.87) were significantly higher than that for robust people. Furthermore, among participants who developed disabilities within 5 years (n = 1481), the risk of post-disability death for pre-frailty was not different from that for robust (HR: 1.49, 95% CI: 0.99–2.24), but frailty showed a higher risk of post-disability death than did robust people. (HR: 1.75, 95% CI: 1.13–2.72). In the sex-stratified analysis, although the female group showed no association between frailty status and post-disability death (HR: 1.21, 95% CI: 0.63–2.33 in pre-frailty; HR: 1.24, 95% CI: 0.60–2.57 in frailty), the male group showed higher risk of post-disability death in both pre-frailty (HR: 1.74, 95% CI: 1.03–2.96) and frailty (HR: 2.32, 95% CI: 1.32–4.09). Conclusions: Physical frailty shortens the period from disability onset to death. Additionally, the impact of frailty on post-disability death is greater for males than for females. Our findings suggest that physical frailty is an important clinical indicator distinct from disability and that interventions to prevent and address frailty in men need further investigation.

DOI： 10.1111/jgs.18725

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Kiuchi Y., Doi T., Tsutsumimoto K., Nakakubo S., Kurita S., Nishimoto K., Makizako H., Shimada H. . Association between dietary diversity and cognitive impairment in community-dwelling older adults . Geriatrics and Gerontology International24 ( 1 ) 75 - 81 2023年12月

記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：Geriatrics and Gerontology International

Aim: The present study aimed to examine whether dietary diversity is associated with cognitive impairment, including mild cognitive impairment (MCI), in community-dwelling older Japanese adults. Methods: This cross-sectional study was carried out in a general community setting. MCI and global cognitive impairment (GCI) were assessed using the Mini-Mental State Examination and National Center for Geriatrics and Gerontology-Functional Assessment Tool, which are multicomponent neurocognitive tests that include memory attention, executive function and processing speed. Dietary diversity was assessed using the diet variety score. The diet variety score assessed the 1-week consumption frequency of 10 food groups, and either 0 or 1 point was allocated to each category based on the following responses: (i) “eat almost every day” (1 point); and (ii) “not eaten almost daily” (0 points). Older adults with a diet variety score of ≥3 points were defined as having high dietary diversity. Results: Data included 8987 older adults (mean age 73.9 ± 5.5 years; men 44.3%). The overall prevalences of MCI and GCI were 17.1% (n = 1538) and 8.4% (n = 753), respectively. The proportion of patients with a high dietary diversity was 69.9% (n = 6286). Multinomial logistic regression analysis revealed high dietary diversity was associated with MCI (OR 0.83, 95% CI 0.73–0.94) and GCI (OR 0.77, 95% CI 0.65–0.92) after adjusting for covariates. Conclusions: This study had a large sample size of older Japanese adults, and showed that high dietary diversity was associated with a lower proportion of MCI and GCI among older adults. Geriatr Gerontol Int 2024; 24: 75–81.

DOI： 10.1111/ggi.14762

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Kiuchi Y., Tsutsumimoto K., Doi T., Kurita S., Nishimoto K., Makizako H., Shimada H. . Effect of dietary diversity on incident of disability in community-dwelling older adults with sarcopenia: A 40-month follow-up longitudinal study . Maturitas179 107887 - 107887 2023年11月国際誌

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Maturitas

Background: Sarcopenia is a clinical issue in older adults that leads to serious adverse health outcomes, including disability. The present study investigated whether dietary diversity affects the incidence of disability in older adults with sarcopenia. Method: Participants were 759 Japanese older adults with sarcopenia (mean age 77.2 ± 6.0 years; 44.4 % men) who were aged ≥65 years at the time of the examination. Sarcopenia was diagnosed according to the recommendations of the European Working Group on Sarcopenia in Older People 2. Dietary diversity was assessed using a diet variety score. This diet variety score assessed the one-week consumption frequency of ten food groups, according to the following responses: “eat almost every day” (1 point), or “not eaten almost daily” (0 points). Older adults with a diet variety score of 3 or more points were defined as having high dietary diversity. Incident disability was certified by long-term care insurance (mean follow-up duration 32 months). Results: The cumulative disability incidence rates in the older adults with low dietary diversity and high dietary diversity were 23.3 % and 16.9 %, respectively. Cox proportional hazards regression analysis revealed high dietary diversity was associated with a lower risk of incident disability in older adults with sarcopenia (hazard ratio 0.66, 95 % confidence interval 0.47–0.92; p = 0.015), after adjusting for covariates. Conclusions: This longitudinal study revealed that high dietary diversity is associated with a lower risk of incident disability among sarcopenic Japanese older adults.

DOI： 10.1016/j.maturitas.2023.107887

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赤井田将真, 白土大成, 木内悠人, 立石麻奈, 牧迫飛雄馬 . 地域在住高齢女性における自動車運転の経験と認知機能の関連 . 日本作業療法学会抄録集57回 ON - 6 2023年11月

Shiratsuchi D., Makizako H., Tateishi M., Akaida S., Tagata C., Kobayashi M., Takihara T. . Association between muscle weakness and cap-grasping patterns when opening plastic bottles in community-dwelling older adults . Geriatrics and Gerontology International23 ( 10 ) 758 - 760 2023年10月

立石麻奈, 赤井田将真, 桑原祐一, 牧迫飛雄馬 . フレイル高齢者における運動教室が社会交流および運動習慣構築の促進につながった事例 . 日本老年医学会雑誌60 ( 4 ) 482 - 482 2023年10月

赤井田将真, 立石麻奈, 谷口善昭, 木内悠人, 福榮竜也, 白土大成, 愛下由香里, 窪薗琢郎, 大石充, 牧迫飛雄馬 . 自動車運転をしていない地域在住後期高齢女性における免許保有歴と認知機能の関連 . 日本老年医学会雑誌60 ( 4 ) 483 - 483 2023年10月

牧迫飛雄馬 . こころのゆとり . 日本予防理学療法学会雑誌3 ( 1 ) 1 - 1 2023年9月

Araki S., Kiyama R., Nakai Y., Kawada M., Miyazaki T., Takeshita Y., Makizako H. . Sex differences in age-related differences in joint motion during gait in community-dwelling middle-age and older individuals . Gait and Posture103 153 - 158 2023年6月国際誌

記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：Gait and Posture

Background: Walking is the most important mode of human locomotion; however, the ability to walk often decreases with age. Age-related differences in lower-limb kinematics during gait may differ depending on sex. However, the question of the compounded effects of age and sex on gait kinematics remains unsolved. Research question: The present study aimed to clarify the interaction between age and sex in differences in gait kinematics of community-dwelling middle-age and older individuals. Methods: This study included 836 community-dwelling middle-age and older adults (61.8 % female). Joint motion during comfortable gait was measured using magnetic and inertial measurement units. Hip, knee, and ankle joint angles were calculated in the sagittal plane. Participants were divided into four groups according to age: 50–59, 60–69, 70–79, and 80–89 years. The interaction of sex and age on spatiotemporal gait parameters and the peak value of joint angles was analyzed using two-way analysis of variance (ANOVA) and Tukey's post hoc test. Results: Gait speed (F = 43.92, P < 0.001), step length (F = 73.00, P < 0.001), hip extension (F = 12.89, P = 0.002), knee flexion (F = 39.99, P < 0.001), and ankle plantar flexion (F = 27.43, P < 0.001) significantly decreased with age. Significant differences according to sex were observed in all parameters except gait speed. Significant age and sex interaction effects were observed for knee flexion (F = 4.97, P = 0.002) and ankle dorsiflexion (F = 4.04, P = 0.007). Significance: A significant interaction effect of age and sex was observed for peak angle of knee flexion and ankle dorsiflexion during gait. In particular, the knee flexion angle among females during gait began to decrease from 60 years of age, and the decreasing trend was faster and more prominent than that among males.

DOI： 10.1016/j.gaitpost.2023.05.009

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Muto K., Shiratsuchi D., Nanbu K., Sakamoto H., Furuya N., Nakamura K., Yushi M., Tsujita N., Makizako H. . Ability to walk 10 m within the first week of stroke predicts independent outdoor walking and destination . Journal of Stroke and Cerebrovascular Diseases32 ( 8 ) 107145 - 107145 2023年5月国際誌

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Journal of Stroke and Cerebrovascular Diseases

Objectives: We aimed to determine if achieving a 10-m walk target within the first week of stroke onset correlates with independent outdoor walking at discharge and discharge to home for patients with stroke. Materials and methods: This study included 226 patients transferred to the subacute rehabilitation hospital (SRH) between January 2018 and March 2021. Data obtained from hospital records included age, sex, stroke type, lesion side, body mass index, presence of acute treatment, length of days from onset to physical therapy intervention, National Institutes of Health Stroke Scale, length of hospital stay, Functional Independence Measure score, and the ability to complete the 10 m walk target within the first week of stroke onset. The primary outcomes were independent outdoor walking ability and discharge destination from the SRH. A logistic regression analysis was performed to determine if the 10 m walking ability correlated with the outdoor walking ability and discharge destination. Results: Compared with the inability to walk 10 m, walking 10 m independently walking within the first week of stroke onset correlated with the ability to walk independently outdoors at discharge (odds ratio [OR]: 4.38, p = 0.003) and being discharged home (OR: 4.52, p = 0.002), whereas, walking 10 m with assistance was associated with being discharged home (OR: 3.09, p = 0.043). Conclusions: The ability to walk 10 m within the first week of stroke onset may be a helpful marker for prognosis.

DOI： 10.1016/j.jstrokecerebrovasdis.2023.107145

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PubMed

鈴木隆雄, 西田裕紀子, 牧迫飛雄馬, 鄭丞媛, 島田裕之, 大塚礼, 阿部巧 . 地域在住高齢者の健康関連変数の2007年から2017年の推移長寿コホートの総合的研究(ILSA-J) . 日本老年医学会雑誌60 ( Suppl. ) 177 - 178 2023年5月

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