Faculty Profiles - MAKIZAKO Hyuma

Papers - MAKIZAKO Hyuma

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Ayano Tezuka, Takuro Kubozono, Yuichi Akasaki, Shin Kawasoe, Satoko Ojima, Satoshi Yamaguchi, Koji Higuchi, Hyuma Makizako, So Kuwahata, Toshihiro Takenaka, Mayuka Maeda, Seisuke Fujiwara, Mitsuru Ohishi . Impact of frailty and daily living functioning on home blood pressure measurement status. . Blood pressure monitoring 2025International journal

Language：Japanese Publishing type：Research paper (scientific journal)

OBJECTIVE: Home blood pressure (BP) measurement is important for adequate BP control in patients with hypertension. BP targets for frail older adults need to be determined on an individual basis. This study aimed to examine the effect of frailty on home BP measurement status. METHODS: This study enrolled 682 older participants from a community cohort study conducted in Tarumizu City in 2019. We explained that home BP monitors could be lent free of charge to participants who wished to measure their BP at home. We evaluated frailty and daily living functions, such as technology usage, information practice, life management, and social engagement. We investigated how these indicators were associated with the desire to borrow home BP monitors and adherence to home BP measurements. RESULTS: A total of 304 participants agreed to borrow the home BP monitors. Multivariable logistic analysis revealed that the presence of frailty, low technology usage, and information practice were negatively associated with borrowing a home BP monitor, independent of age, sex, BMI, smoking history, and the presence of hypertension, diabetes, and dyslipidaemia. In contrast, the presence of prefrailty and frailty was positively associated with daily home BP measurements, independent of age, sex, BMI, smoking history, presence of hypertension, diabetes, and dyslipidaemia. CONCLUSION: Frailty is associated with a lower desire to monitor home BP, but is associated with higher adherence to home BP monitoring once it is initiated.

DOI： 10.1097/MBP.0000000000000767

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PubMed

Kikuchi K., Takada S., Otsuka S., Nakanishi K., Sakakima H., Makizako H., Tahara N., Uchikado H., Shiomi N., Ooba S., Matsumoto N., Nishiwaki M. . Agricultural or gardening physical activity may slow neurovascular aging and prevent stroke and dementia: an experimental and cross-sectional study . Frontiers in Aging Neuroscience17 1676259 2025

Language：Japanese Publisher：Frontiers in Aging Neuroscience

Background: Agricultural or gardening activity (also known as hobby farming) is a simple strategy that may be effective for maintaining health and preventing lifestyle-related diseases. However, its preventive effect on the development of conditions associated with neurovascular aging (e.g., stroke and dementia) remains unclear. Objective: To comprehensively investigate the preventive role of regular agricultural or gardening physical activity (AGPA) in neurovascular aging and its underlying mechanisms using two approaches. Methods: We conducted an experimental study in which we assessed arterial stiffness, cognitive performance (Flanker and Stroop tests), and circulating biomarkers (e.g., plasmin-α2-plasmin inhibitor complexes, nitric oxide, brain-derived neurotrophic factor) in 12 male students (average age: 22 ± 1 years) before and after three 40-min interventions (resting, cycling, and simulated AGPA) under controlled conditions. We also conducted a cross-sectional study, in which we recruited 161 (79 in the AGPA group and 82 in the control group) hospital-based older individuals (average age: 78 ± 5 years) and assessed their history of stroke, cognitive function, and brain magnetic resonance imaging (MRI) findings. Results: In the experimental study, simulated AGPA reduced arterial stiffness, improved executive cognitive function, and elevated circulating plasmin-α2-plasmin inhibitor complexes, nitric oxide, and brain-derived neurotrophic factor. Brain MRI-assessed cerebral white matter hyperintensities caused by reduced blood flow to brain tissue and stroke prevalence were lower, and cognitive scores (as assessed by the Hasegawa Dementia Scale-Revised) were higher in the AGPA group than in the control group. Conclusion: Our findings suggest that regular AGPA is associated with markers of slower neurovascular aging in older individuals. AGPA induces a combination of general physical activity-related and specific AGPA-related effects; moreover, it may offer similar or even greater benefits than physical activity alone. Therefore, habitual AGPA may serve as an effective preventive strategy for neurovascular aging.

DOI： 10.3389/fnagi.2025.1676259

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伊香孝則, 白土大成, 赤井田将真, 三宅悠斗, 立石麻奈, 倉津諒大, 牧迫飛雄馬 . 一過性のバーチャルリアリティ運動が実行機能と脳血流変化に与える影響 . 理学療法かごしま4 ( 0 ) 23 - 30 2025

Language：Japanese Publisher：公益社団法人鹿児島県理学療法士協会

本研究は，健常な若年成人において，コントロール条件，実運動条件，バーチャルリアリティ（以下，VR）運動条件の3条件を実施し，条件前後での実行機能課題中における脳血流変化および実行機能課題成績の変化を比較検討することを目的とした。14名（平均年齢22.4 ± 1.7歳）を対象に，各条件の実施前後でタブレット端末を用いたストループ課題と近赤外線分光法による前頭前野の脳血流変化を測定した。各条件の実施前後におけるストループ課題の完遂時間は，コントロール条件（p ＝0.005），実運動条件（p = 0.031），VR運動条件（p = 0.022）のすべての条件で有意に短縮したが，有意な脳血流の変化は認めなかった。学習効果がみられた4名を除外した追加解析では，有意な脳血流の変化は認めなかったが，VR運動条件のみストループ課題の完遂時間が有意に短縮した（p = 0.022）。実運動条件，VR運動条件に
おいて各条件前後での実行機能課題中の脳血流変化は認められなかったが，一過性のVR運動が実行機能の改善に有益である可能性が示唆された。

DOI： 10.57357/ptkagoshima.4.0_23

CiNii Research

宮崎宣丞, 竹下康文, 荒木草太, 中島将武, 福田将史, 井上真, 川俣洸翔, 末永卓也, 平田晃士, 國分秀真, 川田将之, 木山良二, 牧迫飛雄馬 . 地域在住者における加齢に伴う歩き始めの歩行戦略の変化 . 基礎理学療法学28 ( Supplement ) S2-1 - S2-1 2025

Daijo Shiratsuchi, Yoshiaki Taniguchi, Shoma Akaida, Mana Tateishi, Yuto Kiuchi, Ryota Kuratsu, Hyuma Makizako . Influence of exercise and dietary habits on the association of alpha‐actinin‐3 gene polymorphisms with physical function and body composition in community‐dwelling individuals aged 60 years and older . Geriatrics & Gerontology International25 ( 2 ) 173 - 181 2024.12

Language：English Publishing type：Research paper (scientific journal) Publisher：Wiley

Aim

Alpha‐actinin 3 (ACTN3) is associated with diminished physical function and muscle mass in older individuals. However, the effects of lifestyle on this relationship remain unclear. This study explored whether the association between ACTN3 polymorphisms and physical function and body composition varied based on exercise and dietary habits.

Methods

A longitudinal analysis of 197 community‐dwelling individuals aged 60 years and older (mean age 72.5 ± 5.9 years, 60.9% women) in the Tarumizu study provided data on ACTN3 gene polymorphisms, with surveys completed in 2019 and 2022 (mean follow‐up 1156 ± 80.0 days). Physical performance (grip strength, walking speed) and body composition (body weight, appendicular skeletal muscle mass [ASMM], and fat mass) were assessed. Genetic polymorphisms were analyzed in oral mucosa samples and categorized into type R allele carriers and type XX alleles (homozygous for minor alleles). Median values determined exercise habits (≤4 days/week or ≥5 days/week) and dietary habits based on high‐protein‐food frequency scores.

Results

The proportion of type XX genetic polymorphism was 26.4%. Two‐way repeated‐measures analysis of covariance showed a significant interaction between genetic polymorphism and time for ASMM (F = 10.552, P = 0.002) in the ≤4 days/week exercise habits group. Significant interactions were observed in grip strength (F = 7.013, P = 0.009) and ASMM (F = 5.347, P = 0.023) for the ≤11 score high‐protein‐intake group.

Conclusions

This association may contribute to accelerated age‐related changes in physical performance and body composition, particularly among individuals with type XX genetic polymorphism who have low exercise habits and a limited intake of high‐protein foods. Geriatr Gerontol Int 2024; ••: ••–••.

DOI： 10.1111/ggi.15042

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Yoshihiko Akasaki, Takayuki Tabira, Michio Maruta, Hyuma Makizako, Suguru Shimokihara, Yuma Hidaka, Taishiro Kamasaki, Wataru Kukizako, Takuro Kubozono, Mitsuru Ohishi . Subjective Memory Complaints Related to Satisfaction With Meaningful Activities Among Community-Dwelling Older Adults . Cureus16 ( 11 ) e73433 2024.11International journal

Language：English Publishing type：Research paper (scientific journal) Publisher：Springer Science and Business Media LLC

Objective This study explores the relationship between subjective memory complaints (SMC) and satisfaction with meaningful activities among community-dwelling older adults. Methods Data were analyzed from 539 older adults without cognitive decline (mean age 74.6 ± 6.1 years, 65.0% female) who participated in a community-based health check survey (Tarumizu Study, 2019). SMC was assessed using four questionnaires, and SMC was determined when at least one of the four questionnaires was applicable. From the Aid for Decision-making in Occupation Choice (ADOC), participants selected meaningful activities. Satisfaction with these selected activities was also evaluated. Satisfaction levels were compared between participants with and without SMC, and the relationship between SMC and satisfaction with meaningful activities was analyzed using multivariate analyses. Results The prevalence of SMC was 63.2% (n = 339). Participants with SMC reported lower satisfaction with meaningful activities compared to those without SMC (p = 0.012). Notably, participants who responded positively to SMC-2 ("Do you forget where you have left things more than you used to?") (p = 0.027) and SMC-4 ("Do other people find you forgetful?") (p = 0.004) had significantly lower satisfaction with meaningful activities. Logistic regression analyses revealed a significant relationship between SMC and satisfaction with meaningful activities after adjusting for covariates (OR, 0.79; 95% CI, 0.633-0.996; p = 0.046). Conclusions There is a relationship between SMC and satisfaction with meaningful activities among community-dwelling older adults. Participation in and satisfaction with meaningful activities may play a role in developing effective support for individuals with SMC.

DOI： 10.7759/cureus.73433

PubMed

Tateishi Mana, Akaida Shoma, Taniguchi Yoshiaki, Kiuchi Yuto, Shiratsuchi Daijo, Makizako Hyuma . The difference in effect between individual exercise and collective exercise in older adults with frailty-A randomized controlled trial- . Nippon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics61 ( 4 ) 447 - 455 2024.10

Language：Japanese Publishing type：Research paper (scientific journal) Publisher：The Japan Geriatrics Society

Aim: To examine the influence of exercises, including individual and collective exercises, on older adults with frail and prefrail.Methods: We enrolled 21 older adults with pre-frail and frail (77.1±3.3 years, 90.5% women). The participants were randomly divided into 2 groups: an individual group (n=11) and a collective group (n=10). They performed exercises for 90 minutes once a week for 12 weeks. The individual groups underwent a multi-component exercise program that included strength training using a training machine. The collective group underwent a multi-component exercise program that included strength training in a chair. We evaluated body composition and physical and cognitive functions. These functions were compared before and after the intervention in each group, and the rates of change in the evaluated items were compared between the 2 groups.Results: In the individual group, after the intervention, BMI (p=0.03) and fat mass (p<0.01) decreased, and the 5 Stand Test (p<0.01) and walking speed (p=0.02) improved. In the collective group, the intervention, 5 Stand Test (p<0.01) and information processing (p=0.03) improved after the intervention. Furthermore, the rate of improvement in the 5 Stand Test was higher in the individual group than in the collective group (p<0.01). Conclusions: In the individual exercise group, the physical function improved and fat mass decreased. The cognitive function improved in the collective exercise group. These findings could serve as the basis for formulating an effective exercise program for frail older adults.

DOI： 10.3143/geriatrics.61.447

Daijo Shiratsuchi, Yoshiaki Taniguchi, Yuto Kiuchi, Shoma Akaida, Hyuma Makizako . Association of alpha-actinin-3 genotype with muscle mass and physical function in community-dwelling older adults . European Geriatric Medicine16 ( 1 ) 15 - 22 2024.10International journal

Language：Japanese Publishing type：Research paper (scientific journal) Publisher：Springer Science and Business Media LLC

Abstract

Purpose

Polymorphisms (rs1815739; R577X) in the gene encoding alpha-actinin-3 (ACTN3) are thought to be associated with body composition and physical function in older people and athletes. RR homozygotes are associated with greater expression of ACTN3 protein in muscle than the X-allele carriers. We aimed to investigate the association between ACTN3 R577X polymorphism and appendicular skeletal muscle mass, walking speed, and muscle strength in older adults.

Methods

A cross-sectional analysis was performed on 265 community-dwelling older adults (mean age 74.0 ± 5.8 years, 63.4% female) who provided data on ACTN3 gene polymorphisms and completed surveys in the Tarumizu study conducted between 2018 and 2019. Genetic polymorphisms were categorized as RR homozygous and X allele. Muscle mass was assessed using the appendicular skeletal muscle mass index (ASMI), and physical function was assessed based on walking speed and relative muscle strength. Those in the bottom 25% for each sex were considered “low” and the association with ACTN3 genotype was examined.

Results

Considering ACTN3 polymorphism, 72 participants were RR homozygotes (27.2%) and 193 were X-allele carriers (72.8%). After adjusting for potential confounders, RR homozygosity was associated with not having low muscle mass (odds ratio 0.39, 95% confidence interval 0.19–0.82, p = 0.013) but not with low walking speed and muscle strength.

Conclusion

The association between ACTN3 genotype and physical function in community-dwelling older adults is not clear; however, it is considered to be associated with muscle mass.

DOI： 10.1007/s41999-024-01080-0

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Other Link： https://link.springer.com/article/10.1007/s41999-024-01080-0/fulltext.html

Yuto Kiuchi, Kota Tsutsumimoto, Kazuhei Nishimoto, Yuka Misu, Tomoka Ohata, Hyuma Makizako, Hiroyuki Shimada . Effect of eating alone and depression symptoms on incident disability among community-dwelling older adults . Nutrition129 112599 - 112599 2024.10International journal

Language：Japanese Publishing type：Research paper (scientific journal) Publisher：Elsevier BV

OBJECTIVES: The intent of the present study was to elucidate the association of eating alone and depressive symptoms with the development of disability among community-dwelling older adults, using a longitudinal study. METHOD: Participants included 4648 Japanese older adults (mean age 73.8 ± 5.4 years; 44.3% men) aged ≥ 65 years at the time of the examination. Eating status was divided into two categories: "Eating with others at least once a day" and "Other." The 15-item Geriatric Depression Scale was used to measure depressive symptoms. Incident disability was certified by long-term care insurance (median duration: 36 months). RESULTS: During a median follow-up at 36 months, 8.0% of the participants developed an incident disability. Adjusted for covariates, the participants who ate alone were associated with a higher hazard ratio of incident disability compared to those who ate with others (hazard ratio: 1.36, 95% confidence interval: 1.05-1.75). However, adjusted for the covariate depressive symptoms, eating alone was not significantly associated with incident disability. Structural equation models revealed that the indirect model confirmed eating alone habits were associated with disability via depressive symptoms. CONCLUSIONS: This study confirmed that eating alone was associated with an incident disability after adjusting for the covariates. Furthermore, the present study suggests an indirect relationship between eating alone and incident disability via depressive symptoms, the result of the structural equation model.

DOI： 10.1016/j.nut.2024.112599

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立石麻奈, 赤井田将真, 谷口善昭, 木内悠人, 白土大成, 牧迫飛雄馬 . フレイル高齢者に対する個別運動と集団運動による効果の相違の検証　ランダム化比較試験 . 日本老年医学会雑誌61 ( 4 ) 447 - 455 2024.10

Language：Japanese Publisher：(一社)日本老年医学会

目的:フレイルの予防・改善を目的とした運動介入において個別運動または集団運動といった運動の実施形態の違いは異なった効果をもたらすことが考えられる.本研究は地域在住のフレイルおよびプレフレイル高齢者を対象に運動介入形態の違い(個別または集団)が心身機能に及ぼす影響を明らかにすることを目的とした.方法:フレイルまたはプレフレイルを有する高齢者21名(平均77.1±3.3歳,女性90.5%)を個別群11名と集団群10名にランダムに割りつけ,週1回90分の運動を12週間実施した.個別群はトレーニングマシンを使用して行う筋力トレーニングを含むマルチコンポーネント運動プログラム,集団群は椅子座位中心,自重での筋力トレーニングを含むマルチコンポーネント運動プログラムを実施した.評価項目は身体組成,身体機能,認知機能とした.介入前後の比較および,群間における変化率の比較を行った.結果:介入前後の比較において個別群でBMI(p=0.03),体脂肪量(p<0.01)で有意な減少が認められ,5回立ち座り(p<0.01),歩行速度(p=0.02)が有意に改善した.集団群では,5回立ち座り(p<0.01),情報処理機能(p=0.03)で有意な改善が認められた.群間における変化率の比較では5回立ち座りにおいて個別群は集団群と比較して有意な改善が認められた(p=0.01).結論:運動の実施形態に関わらず,身体機能の改善が示され,個別群のみでBMI,体脂肪量の減少,集団群のみで認知機能の改善がみられた.フレイルおよびプレフレイル高齢者における運動介入において運動の実施形態による効果の特性を考慮することは,個人の背景に則した運動プログラム作成の一助になりうる.(著者抄録)

白土大成, 赤井田将真, 三宅悠斗, 竹中俊宏, 窪薗琢郎, 大石充, 大塚礼, 牧迫飛雄馬 . 地域在住高齢者におけるフレイルおよび内在的能力と主観的健康感の関連 . 日本サルコペニア・フレイル学会雑誌8 ( Suppl. ) 175 - 175 2024.10

Hyuma Makizako, Shoma Akaida, Mana Tateishi, Daijo Shiratsuchi, Ryoji Kiyama, Takuro Kubozono, Toshihiro Takenaka, Mitsuru Ohishi . A Three-Year Longitudinal Follow-Up Study: Does Mild Cognitive Impairment Accelerate Age-Related Changes in Physical Function and Body Composition? . Cureus16 ( 9 ) e68605 2024.9International journal

Language：English Publishing type：Research paper (scientific journal) Publisher：Springer Science and Business Media LLC

Age-related declines in physical function, body composition, and cognitive function are interrelated. This prospective study aimed to examine the impact of mild cognitive impairment (MCI) on age-related changes in physical function and body composition among community-dwelling older adults. We analyzed data from 180 older adults (aged ≥70 years) who completed a longitudinal assessment of physical function and body composition in the community. Physical function included grip strength and time taken to walk 10 m at normal and maximum pace. Body composition assessments calculated the body mass index (BMI) and appendicular skeletal muscle index (ASMI) using bioelectrical impedance analysis at baseline and three-year follow-up assessments. MCI was defined as values below the age- and education-adjusted reference threshold in several tests, including memory, attention, executive function, and processing speed. Participants were divided into the MCI and non-MCI groups based on their MCI status at baseline. A two-way repeated-measures analysis of covariance (ANCOVA), adjusting for age and gender, was used to analyze the group (MCI and non-MCI) by time (baseline and three-year follow-up) interaction. Thirty participants (16.7%) had MCI at baseline. The repeated-measures ANCOVA indicated that no variables had significant group by time interactions. Stratified analyses by gender (repeated-measures ANCOVA, adjusted for age) confirmed a significant group by time interaction on BMI (F=5.63, p=0.02) and ASMI (F=6.33, p=0.01) among women. Older women with MCI may experience a greater impact of the acceleration of shrinking and age-related decline in muscle mass. The close associations of MCI with shrinking and muscle mass loss have important implications for targeting interventions among MCI women.

DOI： 10.7759/cureus.68605

PubMed

古谷直弘, 四宮明宏, 白土大成, 土方麻衣, 坂本勇斗, 武藤健人, 牧迫飛雄馬 . 胃癌・大腸癌患者における術前のPossible Sarcopeniaと術後の合併症および在院日数との関連　後ろ向き観察研究 . 日本がん・リンパ浮腫理学療法学会誌2 39 - 47 2024.9

Language：Japanese Publisher：(一社)日本がん・リンパ浮腫理学療法学会

【目的】本研究の目的は、胃癌または大腸癌を有する患者の術前のPossible Sarcopenia(PS)と握力の低下、5回椅子起立時間の延長と術後の合併症の発生および在院日数との関連を検討することとした。【方法】対象は、胃癌または大腸癌の術後に自宅退院した患者75例とした。Asian Working Group for Sarco-penia 2019に準じて術前のPS、握力の低下、5回椅子起立時間の延長を判定し、術後の合併症の発生と在院日数との関連を調査した。【結果】術前のPSは、術後の合併症の発生と在院日数の長期化との関連が認められた。握力の低下、5回椅子起立時間の延長は、術後の合併症の発生と在院日数の長期化との関連が認められなかった。【結論】術前のPSは、胃癌または大腸癌を有する患者の術後の合併症の発生と在院日数の長期化との関連が示唆された。(著者抄録)

Tomoya Ishigaki, Shogo Misu, Toshinori Miyashita, Daisuke Matsumoto, Midori Kamiya, Akio Okamae, Tatsuya Ogawa, Hikaru Ihira, Yoshiaki Taniguchi, Takeshi Ohnuma, Tomohisa Chibana, Natsu Morikawa, Tome Ikezoe, Hyuma Makizako . Effects of Walking-Only Intervention on Physical Function, Fall-Related Outcomes, and Health-Related Quality of Life in Community-Dwelling Older Adults: A Systematic Review and Meta-Analysis. . Journal of aging and physical activity33 ( 1 ) 1 - 13 2024.8Reviewed International journal

Language：English Publishing type：Research paper (scientific journal)

This study aimed to determine the effects of walking-only intervention (walking was the only exercise in which people participated) on physical function, fall-related outcomes, and health-related quality of life in community-dwelling older adults. We conducted a systematic search across five electronic databases, assessing risk of bias using Minds Manual for Guideline Development. Meta-analyses were performed, and pooled standardized mean differences were calculated. Nine studies (a total of 1,309 participants) were included, showing that walking-only interventions improved walking endurance (standardized mean difference: 1.11, 95% confidence interval: [0.08, 2.15]) and health-related quality of life (standardized mean difference: 0.71, 95% confidence interval: [0.18, 1.25]). However, there were no significant improvements in other outcomes. The certainty of the evidence based on the Grading of Recommendations, Assessment, Development, and Evaluation approach for all outcomes was graded as very low, primarily due to significant inconsistency and imprecision. Our results suggest that walking-only intervention can be effective for enhancing walking endurance and health-related quality of life for community-dwelling older adults. Further studies are required to investigate the effects of walking-only intervention. This need stems from the limited number of randomized controlled trials, heterogeneous intervention settings and results, and the very low certainty of the evidence.

DOI： 10.1123/japa.2023-0183

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PubMed

鈴木隆雄, 鄭丞媛, 西田裕紀子, 大塚礼, 島田裕之, 牧迫飛雄馬, 金憲経, 大渕修一, 河合恒, 藤原佳典, 阿部巧, 小島成実, 平野浩彦, 増井幸恵, 稲垣宏樹, 吉田祐子, 飯島勝矢, 吉村典子, 山田実, 渡辺修一郎, 近藤克則, 村木功, 岩佐一 . 地域在宅高齢者における高次生活機能について　ILSA-JにおけるJST版活動能力指標の分析から . 応用老年学18 ( 1 ) 107 - 116 2024.8

Language：Japanese Publisher：(一社)日本応用老年学会

日本は急速な超高齢社会を迎え,平均寿命の著しい伸びとともに,高齢者の生活機能も大きく変容し,健康水準の高い活力ある高齢者が増加している.本研究では,我が国の地域在宅高齢者を対象とした老化に関する多数のコホート研究の統合研究(「長寿コホートの統合的研究;Integrated Longitudinal Study on Aging in Japan:ILSA-J」)で収集された高次生活機能評価指標であるJST版活動能力指標(JST-IC)を用いて,現代の地域在宅高齢者における生活活動能力の現状を報告した.JST-ICでは総合スコアおよび4項目の下位尺度(新機器利用,情報収集,生活マネジメント,社会参加)について性別および年齢階級別の平均値と標準偏差を算出した.その結果,男女間では情報収集以外の全ての項目で性差が認められ,年齢階級間では男女ともに全ての項目で有意差が認められ,加齢に伴いスコアは低下していた.本研究では,高齢者の高次生活機能の一端を明らかにし,今後の利活用に資する資料とした.(著者抄録)

鈴木隆雄, JEONG Seungwon, 鈴木隆雄, JEONG Seungwon, 西田裕紀子, 大塚礼, 島田裕之, 牧迫飛雄馬, KIM Hunkyung, KIM Hunkyung, 大渕修一, 河合恒, 藤原佳典, 阿部巧, 小島成実, 平野浩彦, 増井幸恵, 稲垣宏樹, 吉田祐子, 飯島勝矢, 飯島勝矢, 吉村典子, 山田実, 渡辺修一郎, 近藤克則, 近藤克則, 村木功, 岩佐一 . High Level of Functional Capacity Assessed by Japan Science and Technology Agency Index of Competence among Community-Dwelling Older Adults in Japan: Findings from the ILSA-J integrated Cohort Study. . 応用老年学18 ( 1 ) 107 - 116 2024.8

鈴木隆雄, 鄭丞媛, 西田裕紀子, 大塚礼, 島田裕之, 牧迫飛雄馬, 金憲経, 大渕修一, 河合恒, 藤原佳典, 阿部巧, 小島成実, 平野浩彦, 増井幸恵, 稲垣宏樹, 吉田祐子, 飯島勝矢, 吉村典子, 山田実, 渡辺修一郎, 近藤克則, 村木功, 岩佐一 . 地域在宅高齢者における高次生活機能について ILSA-JにおけるJST版活動能力指標の分析から . 応用老年学18 ( 1 ) 107 - 116 2024.8

Language：Japanese Publisher：(一社)日本応用老年学会

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Yuto Kiuchi, Hyuma Makizako, Mika Kimura, Yuki Nakai, Yoshiaki Taniguchi, Shoma Akaida, Mana Tateishi, Takuro Kubozono, Toshihiro Takenaka, Hiroyuki Shimada, Mitsuru Ohishi . Association of combined low physical activity and low dietary diversity with mild cognitive impairment among community-dwelling Japanese older adults. . Annals of geriatric medicine and research28 ( 4 ) 453 - 459 2024.7International journal

Language：English Publishing type：Research paper (scientific journal)

OBJECTIVE: This study aimed to investigate the potential association between the combination of low physical activity and low dietary diversity with mild cognitive impairment (MCI) in older Japanese adults. METHODS: Data from 600 older adults (mean age 74.1 ± 6.4 years; 62.0% women) were analyzed. We evaluated dietary variety based on the Food Frequency Score (FFS) (maximum 30 points) by assessing the one-week consumption frequencies of ten foods. An FFS of ≤ 16 indicated low dietary diversity. We assessed MCI using the National Center for Geriatrics and Gerontology (NCGG) Functional Assessment Tool. Physical activity levels was determined based on participant responses to two questions: "Do you engage in moderate levels of physical exercise or sports aimed at health?" and "Do you engage in low levels of physical exercise aimed at health?". Participants who responded "No" to both questions were classified as having low physical activity levels. We classified the participants into robust, low-dietary diversity, low-physical activity, and coexistence groups. RESULTS: The overall prevalence of MCI was 20.7%, with rates in the robust, low dietary diversity, low physical activity, and coexistence groups of 17.7%, 24.7%, 25.0%, and 41.9%, respectively. Multiple logistic regression analysis revealed that low dietary diversity and physical activity were associated with MCI in older adults (odds ratio [OR] 2.80, 95% confidence interval [CI] 1.22-6.28). CONCLUSIONS: The results of the present study demonstrated the association of the co-occurrence of low dietary diversity and low physical activity with MCI. Older adults with both risk factors may require early detection, as well as physical activity and dietary interventions.

DOI： 10.4235/agmr.24.0080

Scopus

PubMed

Tatsuya Fukuei, Shoma Akaida, Yoshiaki Taniguchi, Daijo Shiratsuchi, Yuto Kiuchi, Mana Tateishi, Yukari Aishita, Ryota Kuratsu, Hyuma Makizako . Associations between driving status, frequency of transport use after driving cessation, and social frailty among middle-aged and older people aged 60 years and older . Annals of Geriatric Medicine and Research28 ( 4 ) 437 - 444 2024.7International journal

Language：English Publishing type：Research paper (scientific journal) Publisher：The Korean Geriatrics Society

BACKGROUND: The use of transport other than cars is a modifiable factor in the association between driving cessation and social frailty. Clarifying this relationship may serve as a new preventive measure against social frailty among current non-drivers. This study examined the potential association of driving status and transport use with social frailty, as well as between the frequency of transport use and social frailty, among current non-drivers. METHODS: This study included 977 middle-aged and older adults (average age, 65.3±4.8 years). The participants were classified as transport users (more than a few times a week) and transport non-users (less than a few times a month). Based on driving status and transport use, the groups were further classified into current driver, current non-driver/transport user, and current non-driver/transport non-user groups. The relationships between driving status, transport use, and social frailty were examined using multiple logistic regression. RESULTS: The current non-driver group and the transport non-user group were significant association with a higher social frailty. The current non-driver/transport user group showed no association with social frailty compared with the current driver group. The odds ratio for the social frailty rate for The current non-driver/transport non-user group was 2.14 (95% confidence interval, 1.25-3.73). CONCLUSIONS: Participants who neither drive nor take transport showed significant associations with increased social frailty. Compared with current driver/transport use, current non-driver/transport non-use was associated with social frailty.

DOI： 10.4235/agmr.24.0071

Scopus

PubMed

Hyuma Makizako, Shoma Akaida, Daijo Shiratsuchi, Mana Tateishi . Are middle-aged and older adult users of physical activity monitors more physically active and at a lower risk of locomotive syndrome? Cross-sectional Web-based Online Survey . Annals of Geriatric Medicine and Research28 ( 3 ) 323 - 329 2024.5International journal

Language：English Publishing type：Research paper (scientific journal) Publisher：The Korean Geriatrics Society

BACKGROUND: Physical inactivity is a risk factor for locomotive syndromes and functional limitations in middle-aged and older adults. Therefore, strategies to promote physical activity should be considered. This study investigated whether users of physical activity monitors were more physically active and exhibited a lower risk of locomotive syndrome, compared with non-users. METHODS: We analyzed data from 742 Japanese adults aged 60-79 years. The participants were surveyed for their use of physical activity monitors in their daily lives. We also assessed the prevalence of locomotive syndrome. RESULTS: We observed significantly higher physical activity levels in users compared with non-users. Moreover, the use of a physical activity monitor was significantly associated with decreased odds of locomotive syndrome (adjusted odds ratio [aOR]=0.48). Significantly lower risk of locomotive syndrome were observed in individuals who had used a monitor for >2 years (aOR=0.42) or had set a personal step goal (aOR=0.32). CONCLUSION: Physical activity monitoring may increase engagement in physical activity-associated behavior. Therefore, monitoring could serve as a useful tool to promote physical health in middle-aged and older adults.

DOI： 10.4235/agmr.24.0040

Scopus

PubMed

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