論文 - 小原 恭子
-
Okamoto R, Ito N, Ide Y, Kitab B, Sakoda Y, Tsukiyama-Kohara K . Development of short hairpin RNA expression vectors targeting the internal ribosomal entry site of the classical swine fever virus genomic RNA. . BMC biotechnology23 ( 1 ) 37 2023年9月査読 国際誌
-
Kenzaburo Yamaji, Sadahiro Iwabuchi, Yuko Tokunaga, Shinichi Hashimoto, Daisuke Yamane, Sakiko Toyama, Risa Kono, Bouchra Kitab, Kyoko Tsukiyama-Kohara*, Yosuke Osawa, Yukiko Hayashi, Tsunekazu Hishima, Chise Tateno, Kiminori Kimura, Takeshi Okanoue, Michinori Kohara . Molecular insights of a CBP/β-catenin-signaling inhibitor on nonalcoholic steatohepatitis-induced liver fibrosis and disorder . Biomedicine & Pharmacotherapy166 115379 2023年8月査読 国際共著
-
Ushirozako G, Noda Y, Murayama N, Kawaguchi H, Tsukiyama-Kohara K, Yamazaki H, Uno Y . Newly Identified Tree Shrew Cytochrome P450 2A13 (CYP2A13) is Expressed in Liver and Lung and Encodes a Functional Drug-Metabolizing Enzyme Similar to Dog CYP2A13 and Pig CYP2A19. . Drug metabolism and disposition: the biological fate of chemicals 2023年5月査読 国際誌
-
Uno Y, Jikuya S, Noda Y, Oguchi A, Murayama N, Kawaguchi H, Tsukiyama-Kohara K, Yamazaki H . Newly identified cytochrome P450 3A genes of tree shrews and pigs are expressed and encode functional enzymes. . Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 109579 2023年5月査読 国際誌
-
Yoshida O, Akbar SMF, Imai Y, Sanada T, Tsukiyama-Kohara K, Miyazaki T, Kamishita T, Miyake T, Tokumoto Y, Hikita H, Tsuge M, Shimizu M, Al Mahtab M, Aguilar JC, Guillen G, Kohara M, Hiasa Y . Intranasal therapeutic vaccine containing HBsAg and HBcAg for patients with chronic hepatitis B; 18 months follow-up results of phase IIa clinical study. . Hepatology research : the official journal of the Japan Society of Hepatology 2023年3月査読 国際誌
-
Uno Y, Noda Y, Murayama N, Tsukiyama-Kohara K, Yamazaki H . Novel cytochrome P450 1 (CYP1) genes in tree shrews are expressed and encode functional drug-metabolizing enzymes. . Comparative biochemistry and physiology. Toxicology & pharmacology : CBP265 109534 2023年3月査読 国際誌
-
Kitab B, Tsukiyama-Kohara K . Regulatory Role of Ribonucleotide Reductase Subunit M2 in Hepatocyte Growth and Pathogenesis of Hepatitis C Virus. . International journal of molecular sciences24 ( 3 ) 2023年1月査読 国際誌
-
Kayesh MEH, Khalil I, Kohara M, Tsukiyama-Kohara K . Increasing Dengue Burden and Severe Dengue Risk in Bangladesh: An Overview. . Tropical medicine and infectious disease8 ( 1 ) 2023年1月査読 国際誌
-
Kayesh MEH, Kohara M, Tsukiyama-Kohara K . TLR agonists as vaccine adjuvants in the prevention of viral infections: an overview. . Frontiers in microbiology14 1249718 2023年査読 国際誌
-
Kayesh MEH, Kohara M, Tsukiyama-Kohara K . Epidemiology and Risk Factors for Acute Viral Hepatitis in Bangladesh: An Overview. . Microorganisms10 ( 11 ) 2022年11月査読 国際誌
-
Uno Y, Ushirozako G, Uehara S, Murayama N, Fujiki Y, Kawaguchi H, Tsukiyama-Kohara K, Yamazaki H . Newly identified tree shrew cytochrome P450 2B6 (CYP2B6) and pig CYP2B6b are functional drug-metabolising enzymes. . Xenobiotica; the fate of foreign compounds in biological systems 1 - 10 2022年11月査読 国際誌
-
Kayesh MEH, Hashem MA, Maetani F, Goto A, Nagata N, Kasori A, Imanishi T, Tsukiyama-Kohara K . Molecular Insights into Innate Immune Response in Captive Koala Peripheral Blood Mononuclear Cells Co-Infected with Multiple Koala Retrovirus Subtypes. . Pathogens (Basel, Switzerland)11 ( 8 ) 2022年8月査読 国際誌
-
Characterization of host factors associated with the internal ribosomal entry sites of foot-and-mouth disease and classical swine fever viruses. . 12 ( 1 ) 6709 2022年4月査読 国際共著
-
Kayesh MEH, Kohara M, Tsukiyama-Kohara K . An Overview of Recent Insights into the Response of TLR to SARS-CoV-2 Infection and the Potential of TLR Agonists as SARS-CoV-2 Vaccine Adjuvants. . Viruses13 ( 11 ) 2021年11月査読 国際誌
-
Kayesh MEH, Sanada T, Kohara M, Tsukiyama-Kohara K . Tree Shrew as an Emerging Small Animal Model for Human Viral Infection: A Recent Overview. . Viruses13 ( 8 ) 2021年8月査読 国際誌
-
Hashem MA, Kayesh MEH, Maetani F, Eiei T, Mochizuki K, Ochiai S, Ito A, Ito N, Sakurai H, Asai T, Tsukiyama-Kohara K . Koala retrovirus (KoRV) subtypes and their impact on captive koala (Phascolarctos cinereus) health. . Archives of virology166 ( 7 ) 1893 - 1901 2021年7月査読 国際誌
-
Makoto Saito1,*, Yasushi Itoh2,*, Fumihiko Yasui1,*, Tsubasa Munakata1, Daisuke Yamane1, Makoto Ozawa3, Risa Ito4, Takayuki Katoh4, Hirohito Ishigaki2, Misako Nakayama2, Shintaro Shichinohe2, Kenzaburo Yamaji1, Naoki Yamamoto1, Ai Ikejiri1, Tomoko Honda1, Takahiro Sanada1, Yoshihiro Sakoda5, Hiroshi Kida6, Le Thi Quynh Mai7, Yoshihiro Kawaoka8, Kazumasa Ogasawara2, Kyoko Tsukiyama-Kohara3,†, Hiroaki Suga4,†, and Michinori Kohara . Targeted macrocycles hamper hemagglutinin adsorption and fusion, and have antiviral effects in murine and macaque models of influenza . Nature Communications12 ( 1 ) 2654 2021年5月査読 国際共著
-
Abounouh K. . Blocking neddylation elicits antiviral effect against hepatitis B virus replication . Molecular Biology Reports 2021年査読 国際誌
-
Kayesh M.E.H. . Mammalian animal models for dengue virus infection: a recent overview . Archives of Virology167 ( 1 ) 31 - 44 2021年査読 国際誌
-
Takagi A, Amako Y, Yamane D, Kitab B, Tokunaga Y, El-Gohary A, Kohara M, Tsukiyama-Kohara K . Longer Poly(U) Stretches in the 3'UTR Are Essential for Replication of the Hepatitis C Virus Genotype 4a Clone in <i>in vitro</i> and <i>in vivo</i>. . Frontiers in microbiology12 764816 2021年査読 国際誌