論文 - 小原 恭子
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Ushirozako G, Murayama N, Tsukiyama-Kohara K, Yamazaki H, Uno Y . Novel tree shrew cytochrome P450 2Ds ( CYP2D8a and CYP2D8b ) are functional drug-metabolizing enzymes that metabolize bufuralol and dextromethorphan. . Drug metabolism and disposition: the biological fate of chemicals 2024年1月査読 国際誌
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Uno Y, Makiguchi M, Ushirozako G, Tsukiyama-Kohara K, Shimizu M, Yamazaki H . Molecular and functional characterization of flavin-containing monooxygenases (FMO1-6) in tree shrews. . Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 109835 2024年1月査読 国際誌
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Kayesh MEH, Nazneen H, Kohara M, Tsukiyama-Kohara K . An effective pan-serotype dengue vaccine and enhanced control strategies could help in reducing the severe dengue burden in Bangladesh-A perspective. . Frontiers in microbiology15 1423044 2024年査読 国際誌
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Hasan MN, Rahman MM, Husna AA, Arif M, Iwanaga T, Tsukiyama-Kohara K, Jasineviciute I, Kato D, Nakagawa T, Miura N . Elevated expression of miR-301a and its functional roles in canine oral melanoma. . Veterinary and comparative oncology 2023年12月査読 国際誌
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Uno Y, Minami Y, Tsukiyama-Kohara K, Murayama N, Yamazaki H . Identification of cytochrome P450 2C18 and 2C76 in tree shrews: P450 2C18 effectively oxidizes typical human P450 2C9/2C19 chiral substrates warfarin and omeprazole with less stereoselectivity. . Biochemical pharmacology 115990 2023年12月査読 国際誌
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Ngwe Tun MM, Nwe KM, Balingit JC, Takamatsu Y, Inoue S, Pandey BD, Urano T, Kohara M, Tsukiyama-Kohara K, Morita K . A Novel, Comprehensive A129 Mouse Model for Investigating Dengue Vaccines and Evaluating Pathogenesis. . Vaccines11 ( 12 ) 2023年12月査読 国際誌
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Kayesh MEH, Kohara M, Tsukiyama-Kohara K . Effects of neddylation on viral infection: an overview. . Archives of virology169 ( 1 ) 6 2023年12月査読 国際誌
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Akter L, Hashem MA, Rakib TM, Rashid MHO, Hossain KA, Akhter R, Utsunomiya M, Kitab B, Hifumi T, Miyoshi N, Maetani F, Tsukiyama-Kohara K . Investigation of koala retrovirus in captive koalas with pneumonia and comparative analysis of subtype distribution. . Archives of virology168 ( 12 ) 298 2023年11月査読 国際誌
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Ushirozako G, Murayama N, Tsukiyama-Kohara K, Yamazaki H, Uno Y . Tree shrew cytochrome P450 2E1 is a functional enzyme that metabolises chlorzoxazone and p-nitrophenol. . Xenobiotica; the fate of foreign compounds in biological systems 1 - 11 2023年11月査読 国際誌
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Hossain KA, Akhter R, Rashid MHO, Akter L, Utsunomiya M, Kitab B, Mm N, Hishiki T, Kohara M, Morita K, Tsukiyama-Kohara K . Suppression of dengue virus replication by the French maritime pine extract Pycnogenol®. . Virus research 199244 2023年10月査読 国際誌
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Okamoto R, Ito N, Ide Y, Kitab B, Sakoda Y, Tsukiyama-Kohara K . Development of short hairpin RNA expression vectors targeting the internal ribosomal entry site of the classical swine fever virus genomic RNA. . BMC biotechnology23 ( 1 ) 37 2023年9月査読 国際誌
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Kenzaburo Yamaji, Sadahiro Iwabuchi, Yuko Tokunaga, Shinichi Hashimoto, Daisuke Yamane, Sakiko Toyama, Risa Kono, Bouchra Kitab, Kyoko Tsukiyama-Kohara*, Yosuke Osawa, Yukiko Hayashi, Tsunekazu Hishima, Chise Tateno, Kiminori Kimura, Takeshi Okanoue, Michinori Kohara . Molecular insights of a CBP/β-catenin-signaling inhibitor on nonalcoholic steatohepatitis-induced liver fibrosis and disorder . Biomedicine & Pharmacotherapy166 115379 2023年8月査読 国際共著
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Ushirozako G, Noda Y, Murayama N, Kawaguchi H, Tsukiyama-Kohara K, Yamazaki H, Uno Y . Newly Identified Tree Shrew Cytochrome P450 2A13 (CYP2A13) is Expressed in Liver and Lung and Encodes a Functional Drug-Metabolizing Enzyme Similar to Dog CYP2A13 and Pig CYP2A19. . Drug metabolism and disposition: the biological fate of chemicals 2023年5月査読 国際誌
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Uno Y, Jikuya S, Noda Y, Oguchi A, Murayama N, Kawaguchi H, Tsukiyama-Kohara K, Yamazaki H . Newly identified cytochrome P450 3A genes of tree shrews and pigs are expressed and encode functional enzymes. . Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 109579 2023年5月査読 国際誌
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Yoshida O, Akbar SMF, Imai Y, Sanada T, Tsukiyama-Kohara K, Miyazaki T, Kamishita T, Miyake T, Tokumoto Y, Hikita H, Tsuge M, Shimizu M, Al Mahtab M, Aguilar JC, Guillen G, Kohara M, Hiasa Y . Intranasal therapeutic vaccine containing HBsAg and HBcAg for patients with chronic hepatitis B; 18 months follow-up results of phase IIa clinical study. . Hepatology research : the official journal of the Japan Society of Hepatology 2023年3月査読 国際誌
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Uno Y, Noda Y, Murayama N, Tsukiyama-Kohara K, Yamazaki H . Novel cytochrome P450 1 (CYP1) genes in tree shrews are expressed and encode functional drug-metabolizing enzymes. . Comparative biochemistry and physiology. Toxicology & pharmacology : CBP265 109534 2023年3月査読 国際誌
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Kitab B, Tsukiyama-Kohara K . Regulatory Role of Ribonucleotide Reductase Subunit M2 in Hepatocyte Growth and Pathogenesis of Hepatitis C Virus. . International journal of molecular sciences24 ( 3 ) 2023年1月査読 国際誌
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Kayesh MEH, Khalil I, Kohara M, Tsukiyama-Kohara K . Increasing Dengue Burden and Severe Dengue Risk in Bangladesh: An Overview. . Tropical medicine and infectious disease8 ( 1 ) 2023年1月査読 国際誌
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Kayesh MEH, Kohara M, Tsukiyama-Kohara K . TLR agonists as vaccine adjuvants in the prevention of viral infections: an overview. . Frontiers in microbiology14 1249718 2023年査読 国際誌
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Kayesh MEH, Kohara M, Tsukiyama-Kohara K . Epidemiology and Risk Factors for Acute Viral Hepatitis in Bangladesh: An Overview. . Microorganisms10 ( 11 ) 2022年11月査読 国際誌