研究者詳細 - 大脇　哲洋

講演・口頭発表等 - 大脇　哲洋

分割表示 638 件中 581 - 600 件目／全件表示 >>

喜島祐子, 吉中平次, 大脇哲洋, 愛甲孝 . PS-175-5 腋窩郭清後ドレナージ量の検討 : 腋窩リンパ節郭清ラットモデルに対する低脂肪ダイエット . 日本外科学会雑誌 2004年3月一般社団法人日本外科学会

内門泰斗, 奥村浩, 松本正隆, 大脇哲洋, 佐々木健, 喜多芳昭, 尾本至, 瀬戸山徹郎, 有上貴明, 上之園芳一, 石神純也, 喜島裕子, 盛真一郎, 新地洋之, 上野真一, 夏越祥次 . PS-167-4 超高齢者の食道癌に対する外科治療の選択(PS ポスターセッション,第113回日本外科学会定期学術集会) . 日本外科学会雑誌 2013年3月一般社団法人日本外科学会

浦田正和, 奥村浩, 喜多芳昭, 内門泰斗, 佐々木健, 尾本至, 田上聖徳, 盛真一郎, 大脇哲洋, 石神純也, 夏越祥次 . PS-129-7 食道表在性癌におけるFDG-PETの有用性の評価(PS-129 食道悪性-1,ポスターセッション,第114回日本外科学会定期学術集会) . 日本外科学会雑誌 2014年3月一般社団法人日本外科学会

佐々木健, 奥村浩, 内門泰斗, 喜多芳昭, 松本正隆, 大脇哲洋, 石神純也, 夏越祥次 . PS-123-2 超音波内視鏡およびFDG-PET/CTによる食道癌術前リンパ節転移診断能の比較検討(PS-123 食道画像診断,ポスターセッション,第112回日本外科学会定期学術集会) . 日本外科学会雑誌 2012年3月一般社団法人日本外科学会

尾本至, 松本正隆, 内門泰斗, 喜多芳昭, 櫻井俊秀, 佐々木健, 川崎洋太, 瀬戸山徹郎, 奥村浩, 大脇哲洋, 石神純也, 上野真一, 夏越祥次 . PS-087-3 食道扁平上皮癌の転移リンパ節におけるリンパ管新生(PS-087 ポスターセッション(87)食道:基礎-4,第111回日本外科学会定期学術集会) . 日本外科学会雑誌 2011年5月一般社団法人日本外科学会

中条哲浩, 有馬豪男, 平田宗嗣, 溝口資夫, 喜島祐子, 大脇哲洋, 白尾一定, 中野静雄, 石神純也, 吉中平次, 夏越祥次 . PS-075-3 甲状腺腫瘍に対する新しい内視鏡手術(PS-075 ポスターセッション(75)甲状腺,第111回日本外科学会定期学術集会) . 日本外科学会雑誌 2011年5月一般社団法人日本外科学会

内門泰斗, 奥村浩, 松本正隆, 喜多芳昭, 大脇哲洋, 尾本至, 佐々木健, 瀬戸山徹郎, 有上貴明, 上之園芳一, 石神純也, 新地洋之, 上野真一, 夏越祥次 . PS-062-4 食道癌と同時性重複癌の治療についての検討(PS-062 食道悪性-3,第112回日本外科学会定期学術集会) . 日本外科学会雑誌 2012年3月一般社団法人日本外科学会

大脇哲洋, 奥村浩, 内門泰斗, 尾本至, 佐々木建, 松本正隆, 南幸次, 川崎洋太, 石神純也, 根路銘安仁, 夏越祥次 . PS-023-3 インシデント解析に見る外科医に求められる危機対応能力(PS-023 医療安全・教育,ポスターセッション,第114回日本外科学会定期学術集会) . 日本外科学会雑誌 2014年3月一般社団法人日本外科学会

石神純也, 有上貴明, 上之園芳一, 萩原貴彦, 内門泰斗, 喜多芳昭, 佐々木健, 原口尚士, 奥村浩, 大脇哲洋, 夏越祥次 . PS-009-3 stageIV胃癌の化学療法後の手術 : 根治切除はどこまで可能か(PS-009 胃手術適応-1,ポスターセッション,第112回日本外科学会定期学術集会) . 日本外科学会雑誌 2012年3月一般社団法人日本外科学会

大脇哲洋, 吉中平次, 夏越祥次, 松本正隆, 奥村浩, 中野静雄, 愛甲孝 . PS-007-3 血中濃度からみた侵襲の大きな消化器外科手術における予防的抗菌薬投与 . 日本外科学会雑誌 2004年3月一般社団法人日本外科学会

肥後直倫, 内角泰斗, 奥村浩, 松本正隆, 大脇哲洋, 喜多芳昭, 佐々木健, 瀬戸山徹郎, 尾本至, 石神純也, 有上貴明, 上之園芳一, 新地洋之, 上野真一, 夏越祥次 . PS-003-7 Low dose Docetaxel/5FU (Low dose DF)を併用した透析未導入の慢性腎不全食道癌患者に対する根治的化学放射線療法の検討(PS-003 食道化学療法-1,ポスターセッション,第112回日本外科学会定期学術集会) . 日本外科学会雑誌 2012年3月一般社団法人日本外科学会

Natsugoe S., Matsumoto M., Okumura H., Ikeda M., Ishigami S., Owaki T., Takao S., Aikou T. . Prognostic factors in patients with submucosal esophageal cancer . Journal of Gastrointestinal Surgery 2004年7月 Journal of Gastrointestinal Surgery

記述言語：日本語

The detection rate of early-stage esophageal cancer has increased recently. Various types of treatment including endoscopic mucosal resection, blunt dissection, and esophagectomy with extended lymphadenectomy are employed in patients with submucosal esophageal cancer. The purpose of the present study was to analyze prognostic factors in patients with submucosal esophageal cancer. Univariate analysis showed that lymph node metastasis, subdivision of tumor depth, and lymphatic invasion were correlated with prognosis, whereas sex, age, tumor location, surgical procedure, adjuvant therapy, histologic findings, and venous invasion did not affect prognosis. Multivariate analysis demonstrated lymph node metastasis to be the only significant prognostic factor in submucosal esophageal cancer. Although subdivisions of tumor depth did not reach significance as prognostic factors, lymph node metastasis was strongly related to tumor depth. To select the individualized treatment in patients with submucosal esophageal cancer, accurate diagnosis of lymph node metastasis necessitates a combination of imaging methods such as endoscopic ultrasound-guided fine-needle aspiration, computed tomography, and positron emission tomography. © 2004 The Society for Surgery of the Alimentary Tract.

DOI： 10.1016/j.gassur.2004.02.004

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PubMed

Okumura H., Uchikado Y., Matsumoto M., Owaki T., Kita Y., Omoto I., Sasaki K., Sakurai T., Setoyama T., Nabeki B., Matsushita D., Ishigami S., Hiraki Y., Nakajo M., Natsugoe S. . Prognostic factors in esophageal squamous cell carcinoma patients treated with neoadjuvant chemoradiation therapy . International Journal of Clinical Oncology 2013年4月 International Journal of Clinical Oncology

記述言語：日本語

Background: Definitive evaluation of surgical specimens obtained after neoadjuvant chemoradiation therapy (CRT) is important for assessing additional treatment or prognosis in patients with esophageal squamous cell carcinoma (ESCC). In this study, we examined the histological prognostic factors for ESCC patients treated with CRT and determined an appropriate strategy for their evaluation. Patients and methods: The present study involved 38 consecutive ESCC patients who underwent CRT followed by curative operation. CRT consisted of 5-fluorouracil plus cisplatin and 40 Gy of radiation. We examined histological variables as follows: CRT effect on primary tumor (T-effect: T-effective/T-ineffective), tumor depth (pT), lymph node metastases (pN: pN0/N1), number of lymph node metastases (number-pN), lymphatic invasion, and venous invasion. Univariate and multivariate analyses were performed to examine the independent prognostic factors. Survivals and mode of recurrence were then evaluated according to the independent prognostic factors. Results: In the univariate analyses, T-effect, pN, number-pN, lymphatic invasion, and venous invasion were found to be prognostic factors with p < 0.01, and pT was a factor with p < 0.05. In the multivariate analysis, pN and T-effect were independent prognostic factors. The five-year survival rate of pN0 patients was more than 75%, even though the T-effect was poor. The 5-year survival rate of patients judged as pN1/T-effective was 50%, whereas all of the pN1/T-ineffective patients died within 2 years with relapse disease. Conclusion: The evaluation method using both pN status and T-effect is useful for assessing prognosis of ESCC patients treated with neoadjuvant CRT. © 2012 Japan Society of Clinical Oncology.

DOI： 10.1007/s10147-012-0383-y

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PubMed

OKUMURA Hiroshi, UCHIKADO Yasuto, MATSUMOTO Masataka, OWAKI Tetsuhiro, KITA Yoshiaki, OMOTO Itaru, SASAKI Ken, SAKURAI Toshihide, SETOYAMA Tetsuro, NABEKI Bunpei, MATSUSHITA Daisuke, ISHIGAMI Sumiya, HIRAKI Yoshiyuki, NAKAJO Masayuki, NATSUGOE Shoji . Prognostic factors in esophageal squamous cell carcinoma patients treated with neoadjuvant chemoradiation therapy . 2013年4月

Arigami T., Uchikado Y., Omoto I., Sasaki K., Kita Y., Owaki T., Yanagita S., Mori S., Kurahara H., Okumura H., Maemura K., Natsugoe S. . Primary tumor score based on tumor depth and length predicts prognosis in esophageal squamous cell carcinoma . Anticancer Research 2018年9月 Anticancer Research

記述言語：日本語

Aim: To examine the depth of tumor invasion and tumor length and assess the clinical impact of the primary tumor score (PTS), based on a combination of tumor invasion and tumor length, in patients with esophageal squamous cell carcinoma (ESCC). Patients and Methods: A total of 237 patients with ESCC were classified into three PTS groups based on cut-off values for deeper tumor invasion (pT2-T4) and greater tumor length (≥44 mm). A PTS of 2 indicated the presence of both of these abnormalities, 1 indicated one of these abnormalities, and 0 indicated neither abnormality. Results: PTS was significantly positively correlated with depth of tumor invasion, lymph node metastasis, lymphovascular invasion, and stage (all p<0.001). The prognosis differed significantly among the three groups based on PTS (p<0.0001). Multivariate analysis demonstrated that PTS was an independent prognostic factor (p=0.0004). Conclusion: PTS has a clinical utility as a prognostic predictor in patients with ESCC.

DOI： 10.21873/anticanres.12876

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PubMed

Owaki T., Kijima Y., Yoshinaka H., Hirata M., Okumura H., Ishigami S., Nerome Y., Takezaki T., Natsugoe S. . Present status of endoscopic mastectomy for breast cancer . World Journal of Clinical Oncology 2015年6月 World Journal of Clinical Oncology

記述言語：日本語

Endoscopy is now being used for breast cancer surgery. Though it is used for mastectomy, lymph node dissection, and breast reconstruction, its prime use is for mastectomy. Because an incision can be placed inconspicuously in the axillary site, a relatively large Abstract Endoscopy is now being used for breast cancer surgery. Though it is used for mastectomy, lymph node dissection, and breast reconstruction, its prime use is for mastectomy. Because an incision can be placed inconspicuously in the axillary site, a relatively large incision can be created. A retractor with an endoscope, CO<inf>2</inf>, and an abrasion device with the endoscope are used for operation space security. It is extremely rare that an endoscope is used for lymph node dissection. For breast reconstruction, it may be used for latissimus muscle flap making, but an endoscope is rarely used for other reconstructions. Endoscopic mastectomy is limited to certain institutions and practiced hands, and it has not been significantly developed in breast cancer surgery. On the other hand, endoscopic surgery may be used widely in breast reconstruction. With respect to the spread of robotic surgery, many factors remain uncertain.

DOI： 10.5306/wjco.v6.i3.25

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PubMed

Takatori H., Natsugoe S., Okumura H., Matsumoto M., Ishigami S., Owaki T., Aikou T. . Predictive value of COX-2 for the effect of chemoradiotherapy on esophageal squamous cell carcinoma. . Oncology reports 2005年4月 Oncology reports

記述言語：日本語

Cyclooxygenase-2 (COX-2) displays anti-apoptotic functions related to angiogenesis or blocking of bcl-2 functions. COX-2 overexpression has been found in various human malignancies, including esophageal squamous cell carcinoma (ESCC). The present study examined correlations between expression of COX-2 mRNA and ESCC responses to chemoradiotherapy (CRT). Expression of COX-2 mRNA obtained from 29 biopsy specimens before CRT was quantified using reverse transcriptase-polymerase chain reaction (RT-PCR) using Sybr Green I on the Roche LightCycler system. CRT comprised 5-fluorouracil plus cisplatin and 40 Gy of radiation. Mean COX-2 mRNA score was significantly higher in tumors (1222) than in normal epithelium (50; p=0.05). Expression of COX-2 mRNA was high in 14 patients, low in 8 and absent in 7. The effective response to CRT was achieved in 18 patients. Mean COX-2 mRNA score was significantly higher in ineffective cases (2910) than in effective cases (190; p<0.05). CRT was more effective in patients with low COX-2 mRNA expression than in those with high expression. COX-2 mRNA expression in biopsy specimens was closely related to CRT effectiveness. Examination of COX-2 mRNA expression is useful for predicting the effect of CRT in patients with ESCC.

DOI： 10.3892/or.13.4.697

Scopus

Takatori H, Natsugoe S, Okumura H, Matsumoto M, Ishigami S, Owaki T, Aikou T . Predictive value of COX-2 for the effect of chemoradiotherapy on esophageal squamous cell carcinoma. . Oncology reports 2005年4月

東泰志, 夏越祥次, 中別府良昭, 大脇哲洋, 中野静雄, 中条哲浩, 松本正隆, 石神純也, 帆北修一, 馬場政道, 吉中平次, 高尾尊身, 中條政敬, 愛甲孝 . PP582 Sentinel lymph node navigation surgeryに関する基礎的・臨床的検討 : 各臓器の特異性について . 日本外科学会雑誌 2001年3月一般社団法人日本外科学会

馬場政道, 上之園芳一, 馬場道宏, 大脇哲洋, 中野静雄, 草野力, 夏越祥次, 愛甲孝 . PP219058 食道癌術後のフォローアップシステムと延命との関連 . 日本消化器外科学会雑誌 2001年7月一般社団法人日本消化器外科学会

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<大脇 哲洋>

講演・口頭発表等 - 大脇 哲洋

<大脇　哲洋>

講演・口頭発表等 - 大脇　哲洋