Papers - KOSAI Ken-ichiro
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Taro Kamisasanuki, Saori Tokushige, Hiroto Terasaki, Ngin Cin Khai,Yuqing Wang, Taiji Sakamoto, Ken-ichiro Kosai. . Targeting CD9 produces stimulus-independent antiangiogenic effects predominantly in activated endothelial cells during angiogenesis: A novel antiangiogenic therapy . Biochem Biophys Res Commun16 ( 413 ) 128 - 135 2011.9Reviewed
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Yoshiharu Horikawa, Yuqing Wang, Satoshi Nagano, Jun-ichi Kamizono, Minako Ikeda, Setsuro Komiya, Ken-ichiro Kosai. . Assessment of an altered E1B promoter on the specificity and potency of triple-regulated conditionally replicating adenoviruses: implications for the generation of ideal m-CRAs . Cancer Gene Therapy18 ( 10 ) 724 - 733 2011.8Reviewed
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Ken-ichi Murakami, Tatsuru Kaji, Ryuichi Shimono, Yoshihiro Hayashida, Hiroshi Matsufuji, Shinichiro Tsuyama, Rie Maezono, Ken-ichiro Kosai, Hideo Takamatsu. . Therapeutic effects of vitamin A on experimental cholestatic rats with hepatic fibrosis . Pediatr Surg Int27 ( 6 ) 863 - 870 2011.8Reviewed
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Ngin Cin Khai, Kouichi Sakamoto, Hideo Takamatsu, Hiroshi Matsufuji, Ken-ichiro Kosai. . Recombinant soluble form of HB-EGF protein therapy drastically inhibits Fas-mediated fulminant hepatic failure: Implications in clinical application . Hepatol Res41 ( 6 ) 594 - 596 2011.2Reviewed
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Yasunori Okabe, Akira Kusanaga, Tomoyuki Takahashi, Chiaki Mitsumasu, Yoshinaka Murai, Eiichiro Tanaka, Hideo Higashi, Toyojiro Matsuishi, Ken-ichiro Kosai. . Neural Development of Methyl-CpG-Binding Protein 2 Null Embryonic Stem Cells: A System for Studying Rett Syndrome . Brain Res1360 ( 11 ) 17 - 27 2010.11Reviewed
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Miyata S, Takemura G, Kosai KI, Takahashi T, Esaki M, Li L, Kanamori H, Maruyama R, Goto K, Tsujimoto A, Takeyama T, Kawaguchi T, Ohno T, Nishigaki K, Fujiwara T, Fujiwara H, Minatoguchi S. . Anti-Fas Gene Therapy Prevents Doxorubicin-induced Acute Cardiotoxicity through Mechanisms Independent of Apoptosis . Am J Pathol176 ( 2 ) 687 - 698 2010.2Reviewed
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Li L, Okada H, Takemura G, Kosai KI, Kanamori H, Esaki M, Takahashi T, Goto K, Tsujimoto A, Maruyama R, Kawamura I, Kawaguchi T, Takeyama T, Fujiwara T, Fujiwara H, Minatoguchi S. . Postinfarction gene therapy with adenoviral vector expressing decorin mitigates cardiac remodeling and dysfunction . Am J Physiol Heart Circ Physiol97 ( 4 ) 1504 - 1513 2009.8Reviewed
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Umeno H, Chitose S, Murofushi Y, Kosai K, Sato K, Kawahara A, Nakashima T. . Efficacy of autologous fat injection laryngoplasty with an adenoviral vector expressing hepatocyte growth factor in a canine model . J Laryngol Otol123 ( 31 ) 24 - 29 2009.5Reviewed
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Okada H, Takemura G, Kosai K, Tsujimoto A, Esaki M, Takahashi T, Nagano S, Kanamori H, Miyata S, Li Y, Ohno T, Maruyama R, Ogino A, Li L, Nakagawa M, Nagashima K, Fujiwara T, Fujiwara H, Minatoguchi S. . Combined therapy with cardioprotective cytokine administration and antiapoptotic gene transfer in postinfarction heart failure . Am J Physiol Heart Circ Physiol296 ( 3 ) 616 - 626 2009.1Reviewed
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Kondo T, Takemura G, Kosai K, Ohno T, Takahashi T, Esaki M, Goto K, Maruyama R, Murata I, Minatoguchi S, Fujiwara T, Fujiwara H. . Application of an adenoviral vector encoding soluble transforming growth factor-beta type II receptor to the treatment of diabetic nephropathy in mice . Clin Exp Pharmacol Physiol35 ( 11 ) 1288 - 1293 2008.10Reviewed
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Esaki M, Takemura G, Kosai KI, Takahashi T, Miyata S, Li L, Goto K, Maruyama R, Okada H, Kanamori, H, Ogino A, Ushikoshi H, Minatoguchi S, Fujiwara T, Fujiwara H. . Treatment with an adenoviral vector encoding hepatosyte growth factor mitigates established cardiac dysfunction in doxorubicin -induced cardiomyopathy . Am J Physiol Heart Circ Physiol294 ( 2 ) 1048 - 1057 2007.12Reviewed
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Chen XH, Minatoguchi S, Kosai K, Yuge K, Takahashi T, Arai M, Wang N, Misao Y, Lu C, Onogi H, Kobayashi H, Yasuda S, Ezaki M, Ushikoshi H, Takemura G, Fujiwara T, Fujiwara H. . In vivo hepatocyte growth factor gene transfer reduces myocardial ischemiareperfusion injury through its multiple actions . J Card Fail13 ( 10 ) 874 - 883 2007.12Reviewed
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Takahashi T, Kawai T, Ushikoshi H, Nagano S, Oshika H, Inoue M, Kunisada T, Takemura G, Fujiwara H, Kosai K. . Identification and isolation of embryonic stem cell-derived target cells by adenoviral conditional targeting . Mol Ther14 673 - 683 2006.11Reviewed
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Murofushi Y, Nagano S, Kamizono J, Takahashi T, Fujiwara H, Komiya S, Matsuishi T, and Kosai K. . Cell cycle-specific changes in hTERT promoter activity in normal and cancerous cells in adenoviral gene therapy: A promising implication of telomerase-dependent targeted cancer gene therapy . Int J Oncol29 681 - 688 2006.9Reviewed
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Khai NC, Takahashi T, Ushikoshi H, Nagano S, Yuge K, Esaki M, Kawai T, Goto K, Murofushi Y, Fujiwara T, Fujiwara H, Kosai K. . In vivo hepatic HB-EGF gene transduction inhibits Fas-induced liver injury and induces liver regeneration in mice: A comparative study to HGF . J. Hepatol44 1046 - 1054 2006.6Reviewed
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Misao Y, Takemura G, Arai M, Sato S, Suzuki K, Miyata S, Kosai K, Minatoguchi S, Fujiwara T, Fujiwara H. . Bone marrow-derived myocyte-like cells and regulation of repair-related cytokines after bone marrow cell transplantation . Cardiovasc Res69 476 - 490 2006.2Reviewed
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Kagawa T., Takemura G., Kosai K., Murata I., Ohno T., Takahashi T., Esaki M., Maruyama R., Fujiwara T., Ohashi H., Fujiwara H. . Hepatocyte growth factor gene therapy slows down the progression of diabetic nephropathy in db/db mice . Nephron Physiol102 92 - 102 2006.2Reviewed
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Kuge H, Ohashi K, Yokoyama T, Kanehiro H, Hisanaga M, Koyama F, Bumgardner GL, Kosai K, Nakajima Y. . Genetic modification of hepatocytes towards hepatocyte transplantation and liver tissue engineering . Cell Transplant15 1 - 12 2006Reviewed
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Yuge K, Takahashi T, Nagano S, Terazaki Y, Murofushi Y, Ushikoshi H, Kawai T, Khai NC, Nakamura T, Fujiwara H, Kosai K. . Adenoviral Gene Transduction of Hepatocyte Growth Factor Elicits Inhibitory Effects for Hepatoma . Int J Oncol27 77 - 85 2005.7Reviewed
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Kamizono J, Nagano S, Murofushi Y, Komiya S, Fujiwara H, Matsuishi T, Kosai K. . Survivin-responsive conditionally replicating adenovirus exhibits cancer-specific and efficient viral replication . Cancer Res65 5284 - 5291 2005.6Reviewed