Life Science / Oral pathobiological science

Life Science / Tumor biology

Life Science / Virology

Life Science / Oral pathobiological science

Life Science / Oral biological science

Life Science / Molecular biology

Life Science / Experimental pathology

Hiroshima University   Hiroshima University Hospital   Researcher

2019.1 - 2021.3

Hiroshima University   Graduate school of Biomedical Sciences   Assistant Professor

2014.1 - 2018.12

Hiroshima University   Graduate school of Biomedical Sciences   Researcher

2011.10 - 2013.10

Hiroshima University   Graduate school of Biomedical Sciences   Research Assistant

2008.10 - 2011.9

University of Medicine and Pharmacy at Ho Chi Minh city   Oral Pathology   Lecturer

2006.10 - 2008.9

奥 康伸, Nguyen Phuong Thao, 嶋 香織, 下拾石 雄大, 笹平 智則 .  細胞質内のTCF19転座はHNSCCにおけるDNA損傷修復を阻害する(Cytoplasmic TCF19 translocation impairs DNA damage repair in HNSCC) .  日本病理学会会誌112 ( 1 ) 387 - 387   2023.3細胞質内のTCF19転座はHNSCCにおけるDNA損傷修復を阻害する(Cytoplasmic TCF19 translocation impairs DNA damage repair in HNSCC)

冨嶋 彩未, Nguyen Phuong Thao, 嶋 香織, 下拾石 雄大, 笹平 智則 .  口腔癌におけるMCTP1とMCTP2の機能的な差異についての検討 .  日本病理学会会誌112 ( 1 ) 388 - 388   2023.3口腔癌におけるMCTP1とMCTP2の機能的な差異についての検討

嶋 香織, Nguyen Phuong Thao, 下拾石 雄大, 笹平 智則 .  口腔扁平上皮癌におけるMETTL5発現と機能の解析 .  日本病理学会会誌112 ( 1 ) 289 - 290   2023.3口腔扁平上皮癌におけるMETTL5発現と機能の解析

Nguyen Phuong Thao, 嶋 香織, 下拾石 雄大, 笹平 智則 .  KPNA7の増幅および過剰発現がHNSCCの腫瘍浸潤免疫細胞に及ぼす影響(Impacts of KPNA7 amplification and overexpression on tumor infiltrating immune cells of HNSCCs) .  日本病理学会会誌112 ( 1 ) 291 - 291   2023.3KPNA7の増幅および過剰発現がHNSCCの腫瘍浸潤免疫細胞に及ぼす影響(Impacts of KPNA7 amplification and overexpression on tumor infiltrating immune cells of HNSCCs)

Hoang Trong Hung, Phuong Thao Nguyen, Nam Cong Nhat Huynh, Tam Thi Thanh Nguyen, Trang Thi Huyen Tu, Michael George Botelho, Lan Van Nguyen, Kaori Shima, Tomonori Sasahira .  Reliability of online dental final exams in the pre and post COVID-19 era: A comparative study .  PLOS ONE   2023 Reliability of online dental final exams in the pre and post COVID-19 era: A comparative studyReviewed International coauthorship

Kaori Shima, Phuong Thao Nguyen, Yudai Shimojukkoku, Tomonori Sasahira .  Two cases of primordial odontogenic tumor in the maxilla .  Japanese Journal of Diagnostic Pathology40 ( 3 ) 265 - 271   2023Two cases of primordial odontogenic tumor in the maxillaReviewed

Kaori Shima, Phuong Thao Nguyen, Yudai Shimojukkoku, Yuka Kajiya, Tomonori Sasahira .  Solitary circumscribed neuroma of the upper lip: A case report .  Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology   2023Solitary circumscribed neuroma of the upper lip: A case report

Nguyen PT, Kanno K, Pham QT, Kikuchi Y, Kakimoto M, Kobayashi T, Otani Y, Kishikawa N, Miyauchi M, Arihiro K, Ito M, Tazuma S .  Senescent hepatic stellate cells caused by deoxycholic acid modulates malignant behavior of hepatocellular carcinoma .  Journal of Cancer Research and Clinical Oncology146   3255 - 3268   2021Senescent hepatic stellate cells caused by deoxycholic acid modulates malignant behavior of hepatocellular carcinomaReviewed

Kobayashi T, Kanno K, Nguyen PT, Sugiyama A, Kawahara A, Otani Y, Kishikawa N, Ito M, Tazuma S .  Periostin antisense oligonucleotide prevents hepatic steatosis and fibrosis in a mouse model of non-alcoholic steatohepatitis .  Journal of Gastroenterology and Hepatology35   2140 - 2150   2020.12Periostin antisense oligonucleotide prevents hepatic steatosis and fibrosis in a mouse model of non-alcoholic steatohepatitisReviewed

Ohigashi T, Kanno K, Sugiyama A, Nguyen PT, Kishikawa N, Otani Y, Kobayashi T, Matsuo H, Tazuma S .  Protective effect of phosphatidylcholine on lysophosphatidylcholine-induced cellular senescence in cholangiocyte .  J Hepatobiliary Pacreat Sci26   568 - 577   2019.12Protective effect of phosphatidylcholine on lysophosphatidylcholine-induced cellular senescence in cholangiocyteReviewed

Kobayashi T, Kanno K, Nguyen PT, Kishikawa N, Tazuma S .  Molecular mechanism in which periostin induces hepatic steatosis in vivo and in vitro .  Hepatology70   1286 - 1286   2019.5Molecular mechanism in which periostin induces hepatic steatosis in vivo and in vitroReviewed

Nguyen PT, Kanno K, Pham T, Kobayashi T, Tazuma S .  Deoxycholic acid-Induced senescent hepatic stellate cell promote malignant behaviors of hepatocellular carcinogenesis .  Gastroenterology156   2019.5Deoxycholic acid-Induced senescent hepatic stellate cell promote malignant behaviors of hepatocellular carcinogenesisReviewed

Chea C, Miyauchi M, Inubushi T, Okamoto K, Haing S, Nguyen PT, Imanaka H, Takata T .  Bovine lactoferrin reverses programming of epithelial-to-mesenchymal transition in oral squamous cell carcinoma .  Biochem Biophys Res Commun502   142 - 147   2018.12Bovine lactoferrin reverses programming of epithelial-to-mesenchymal transition in oral squamous cell carcinomaReviewed

Nguyen PT, Nguyen D, Chea C, Miyauchi M, Fujii M, Takata T .  Interaction between N-cadherin and decoy receptor-2 regulates apoptosis in head and neck cancer .  Oncotarget9   31516 - 31530   2018.7Interaction between N-cadherin and decoy receptor-2 regulates apoptosis in head and neck cancerReviewed

Kobayashi T, Kanno K, Sugiyama A, Nguyen PT, Kishikawa N, Otani Y, Tazuma S .  Periostin Antisense Oligonucleotide Prevents Hepatic Steatosis and Fibrosis in Mice: A novel strategy for Nonalcoholic Steatohepatitis Treatment .  Hepatology68   2018.5Periostin Antisense Oligonucleotide Prevents Hepatic Steatosis and Fibrosis in Mice: A novel strategy for Nonalcoholic Steatohepatitis TreatmentReviewed

Oka H, Ishida Y, Hong G, Nguyen PT .  Perceptions of dental students in Japanese national universities about studying abroad .  Eur J Dent Educ22   e1 - e6   2018.2Perceptions of dental students in Japanese national universities about studying abroadReviewed International coauthorship

Chea C, Miyauchi M, Inubushi T, N, Subarnbhesaj A, Nguyen PT, Shestha M, Haing S, Ohta K, Takata T .  Molecular mechanism of inhibitory effects of bovine lactoferrin on the growth of oral squamous cell carcinoma .  PLOS ONE13   e0191683   2018.1Molecular mechanism of inhibitory effects of bovine lactoferrin on the growth of oral squamous cell carcinomaReviewed

Subarnbhesaj A, Miyauchi M, Mikuriya A, Nguyen PT, Chanbora C, Ayunintyas NF, Fujita M, Niida S, Takata T .  Roles of VEGF-Flt-1 signaling in malignant behaviors of oral squamous cell carcinoma .  PLOS ONE12   e0187092   2017.11Roles of VEGF-Flt-1 signaling in malignant behaviors of oral squamous cell carcinomaReviewed

Subarnbhesaj A, Miyauchi M, Chea C, Nurina FA, Nguyen PT, Takata T .  Role of VEGF-Flt-1 Signaling in Oral Cancer Progression .  Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology119   136 - 137   2015.3Role of VEGF-Flt-1 Signaling in Oral Cancer ProgressionReviewed

Nguyen PT, Subarnbhesaj A, Miyauchi M, Ogawa I, Takata T .  The FGFR1 inhibitor PD173074 reduces osteoclastogenesis in gingival squamous cell carcinoma .  Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology119   172 - 172   2015.3The FGFR1 inhibitor PD173074 reduces osteoclastogenesis in gingival squamous cell carcinomaReviewed

Nguyen PT, Tsunematsu T, Yanagisawa S, Kudo Y, Miyauchi M, Kamata N, Takata T .  The FGFR-1 inhibitor PD173074 induces mesenchymal-epithelial transition through the transcription factor AP- 1 .  British Journal Cancer109   2248 - 2258   2013.10The FGFR-1 inhibitor PD173074 induces mesenchymal-epithelial transition through the transcription factor AP- 1Reviewed

Yasusei Kudo , Shinji Iizuka, Maki Yoshida, Phuong Thao Nguyen, Samadarani B S M Siriwardena, Takaaki Tsunematsu, Mariko Ohbayashi, Toshinori Ando, Daijiro Hatakeyama, Toshiyuki Shibata, Keiichi Koizumi, Masahiro Maeda, Naozumi Ishimaru, Ikuko Ogawa, Takashi Takata .  Periostin Directly and Indirectly Promotes Tumor Lymphangiogenesis of Head and Neck Cancer .  PLOS ONE7   1 - 14   2012.8Periostin Directly and Indirectly Promotes Tumor Lymphangiogenesis of Head and Neck CancerReviewed

Nguyen PT, Kudo Y, Yoshida M, Takata T .  N-cadherin expression is involved in malignant behavior of head and neck cancer in relation to epithelial- mesenchymal transition .  Histol Histopathol 26   147 - 156   2011.2N-cadherin expression is involved in malignant behavior of head and neck cancer in relation to epithelial- mesenchymal transitionReviewed

Nguyen PT, Kudo Y, Yoshida M, Iizuka S, Ogawa I, Takata T .  N-cadherin expression is correlated with metastasis of spindle cell carcinoma of head and neck region .  Journal of Oral Pathology and Medicine 40   77 - 82   2011.1N-cadherin expression is correlated with metastasis of spindle cell carcinoma of head and neck regionReviewed

SL Priebe, J Aleksejūnienė, C Zed, S Dharamsi, DHQ Thinh, NT Hong, TTK Cuc, Nguyen PT .  Oral squamous cell carcinoma and cultural oral risk habits in Vietnam .  International Journal of Dental Hygiene8   159 - 168   2010.8Oral squamous cell carcinoma and cultural oral risk habits in VietnamReviewed International coauthorship

Yudai Shimojukkoku, Phuong Thao Nguyen, Kaori Shima, Takayuki Ishida, Tomonori Sasahira   Functional analysis of EGR-1 as a tumor suppressor gene in oral squamous cell carcinoma  

The 65th Annual meeting of The Society of Basic Dental Medicine  2023.9  The Society of Basic Dental Medicine

Phuong Thao Nguyen, Kaori Shima, Yudai Shimojukkoku, Yuka Kajiya, Tomonori Sasahira   Amplication of the nuclear import receptor KPNA7 is associated with poor overall survival in head and neck cancer  

The 82th Annual Meeting of The Japanese Cancer Association  2023.9  The Japanese Cancer Association

Kaori Shima, Phuong Thao Nguyen, Yudai Shimojukkoku, Tomonori Sasahira   Analysis of METTL5, a m6A methyltransferase, expression in oral squamous cell carcinoma  

The 65th Annual Meeting of The Society of Basic Dental Medicine  2023.9  The Society of Basic Dental Medicine

Shima K, Nguyen PT, Shimojukkoku Y, Sasahira T   Analysis of METTL5 expression and function in oral squamous cell carcinoma.  

The 112th annual meeting of The Japanese Society Pathology   2023.4  The Japanese Society Pathology

Nguyen PT, Shima K, Shimojukkoku Y, Sasahira T   Impacts of KPNA7 amplification and overexpression on tumor infiltrating immune cells of HNSCCs  

The 112th annual meeting of The Japanese Society Pathology   2023.4  The Japanese Society Pathology

Tomishima A, Nguyen PT, Shima K, Shimojukkoku Y, Sasahira T   The roles of MCTP2 in oral squamous cell carcinoma.  

The 112th annual meeting of The Japanese Society Pathology   2023.4  The Japanese Society Pathology

Oku Y, Nguyen PT, Shima K, Shimojukkoku Y, Sasahira T   Cytoplasmic TCF19 translocation impairs DNA damage repair in HNSCC.  

The 112th annual meeting of The Japanese Society Pathology   2023.4  The Japanese Society Pathology

Nguyen PT, Shima K, Shimojukkoku Y, Sasahira T.   EPS8L3 mediates YAP nuclear translocation and promotes liver tumorigenesis.  

The 112th annual meeting of The Japanese Society Pathology   2023.4  The Japanese Society Pathology

Nguyen PT, Shima K, Sasahira T   New insights into YAP nuclear translocation to promote liver tumorigenesis   International conference

The 81st annual meeting of Japanese Cancer Association   2022.9  Japanese Cancer Association

Nguyen PT, Kanno K, Pham QT, Kobayashi T, Miyauchi M, Arihiro K, Tazuma S, Ito M   Senescent hepatic stellate cells caused by deoxycholic acid modulates malignant behavior of hepatocellular carcinoma   International conference

The 43rd annual meeting of The molecular Biology Society in Japan  2020  The molecular Biology Society in Japan

Nguyen PT, Tazuma S, Otani Y, Ito M   Contributions of hepatic stellate cells into hepatocellular carcinoma   International conference

The 79th annual meeting of Japanese Cancer Association  2020  Japanese Cancer Association

Juraev J, Matsumoto M, Kanno K, Nguyen PT, Tazuma S   Geographic distribution of X-Ray, CT and MRI devices: a comparison between Japan and Uzbekistan   International conference

Wonca  2019  World Organization of Family Doctors

Nguyen PT, Kanno K, Pham QT, Kobayashi T, Tazuma S.   Deoxycholic acid-induced senescent hepatic stellate cells generate inflammatory tumor microenvironment that drives progression in hepatocellular carcinoma  

The 41st Bile acid meeting   2019 

Kobayashi T, Kanno K, Sugiyama A, Nguyen PT, Kishikawa N, Otani Y, Tazuma S   Molecular mechanism in which periostin induces hepatic steatosis in vivo and in vitro   International conference

71st Annual Meeting of American Association for the Study of Liver Disease   2019  American Association for the study of liver diseases

Nguyen PT, Kanno K, Pham T, Kobayashi T, Kishikawa N, Otani Y, Tazuma S   Deoxycholic acid-Induced senescent hepatic stellate cell promote malignant behaviors of hepatocellular carcinogenesis: Implication to Underlying Mechanisms of Metabolic Syndrome-Based Fatty liver and carcinogenesis   International conference

120th Annual Meeting of American Gastroenterological Association   2019  American Gastroenterological Association

Nguyen PT, Kanno K, Pham T, Kobayashi T, Tazuma S   Deoxycholic acid-induced senescent hepatic stellate cells promote invasion and metastasis of hepatocellular carcinoma cells  

The 40th Bile acid meeting  2018  Japanese Bile Acid Association

Ohigashi T, Kanno K, Sugiyama A, Nguyen PT, Kishikawa N, Otani Y, Kobayashi T, Matsuo H, Tazuma S   Protective effect of phosphatidylcholine on lypophosphatidylcholine-induced cellular senescence in cholangiocyte  

The 40th Bile acid meeting   2018 

Nguyen PT, Miyauchi M, Fujii M   The role of molecular triad PlGF/ Flt1/ MMP1 in bone invasion of gingival squamous cell carcinoma.   International conference

The 76th annual meeting of Japanese Cancer Association   2017  Japanese Cancer Asssociation

Kobayashi T, Kanno K, Sugiyama A, Nguyen PT, Kishikawa N, Otani Y, Tazuma S   Periostin Antisense Oligonucleotide Prevents Hepatic Steatosis and Fibrosis in Mice: A novel strategy for Nonalcoholic Steatohepatitis Treatment   International conference

70th Annual Meeting of American Association for the Study of Liver Disease   2017  American Association for the study of liver diseases

Nguyen PT, Nguyen D, Miyauchi M, Fujii M, Takata T.   Overexpression of N-cadherin induces anti-apoptosis effects on cancer cells through TRAIL receptors and caspase pathway   International conference

The 27th Annual Meeting of the Japanese Society of Oral Pathology  2016  the Japanese Society of Oral Pathology

Oka H, Maretaningtias DA, Nguyen PT, Kato K, Nikawa H, Sugiyama M, Sugai M   An assessment of educational program for undergraduate dental students with Japanese-English dual linguistic education system at Hiroshima University (the third and the fourth year)   International conference

The 17th Ottawa Conference  2016  The University of British Columbia

Nguyen PT, Miyauchi M, Fujii M   Interaction between N-cadherin and DcR-2 induces anti-apoptosis through activation of ERK and inhibition of p65   International conference

The 75th annual meeting of Japanese Cancer Association   2016  Japanese Cancer Association

Oka H, Nguyen PT, Kato K   The current status of instruction and curricular content in forensic odontology in Asian countries. Results from the pilot questionnaire survey   Invited International conference

Annual meeting of South East Asia Association for Dental Education   2015 

Oka H, Nguyen PT, Kato K   Undergraduate forensic dental education in Japan   Invited International conference

The 2nd International Symposium   2015 

Oka H, Suardita K, Nguyen PT, Takata T   Assessment of Japanese-English dual linguistic education system at HUD-Study on the factors students expect for the present lectures / practices  

The 33rd annual academic meeting of Japanese Dental Education Association   2014  Japanese Dental Education Association

Nguyen PT, Subarnbhesaj A, Miyauchi M, Ogawa I, Takata T   The FGFR1 inhibitor PD173074 reduces osteoclastognesis in gingival squamous cell carcinoma   International conference

The 17th International Congress on Oral Pathology and Medicine   2014  International Association of Oral and Maxillofacial Pathologists

Subarnbhesaj A, Miyauchi M, Inubushi T, Chanbra C, Nguyen PT, Takata T   Role of VEGF-Flt1- signaling in oral cancer progression.   International conference

The 17th International Congress on Oral Pathology and Medicine   2014  International Association of Oral and Maxillofacial Pathologists

Subarnbhesaj A, Miyauchi M, Inubushi T, Chanbra C, Ayuningtyas NF, Nguyen PT, Takata T   Role of VEGF-Flt-1 signaling in malignant behaviors of oral cancer   International conference

The 30th Meeting of International Academy of Pathology   2014  International Academy of Pathology

Mikuriya A, Subarnbhesaj A, Miyauchi M, Nguyen PT, Takata T   Role of VEGF-Flt-1 signaling in bone invasion of oral cancer.  

The 62nd annual meeting of Japanese association of dental research   2014  Japanese Association for Dental Research

Sugai M, Oka H, Suardita K, Nguyen PT, Takata T, Kato K, Nikawa H   Assessment of Japanese-English dual linguistic education system at HUD-Feedbacks from the lecturers about present conditions and handling  

The 33rd Annual Academic Meeting of Japanese Dental Education Association   2014  Japanese Dental Education Association

Subarnhesaj A, Miyauchi M, Inubushi T, Chanbora C, Nguyen PT, Takata T   The importance of VEGF-Flt-1 pathway in oral cancer progression   International conference

The 5th Hiroshima Conference on Education and Science in Dentistry  2013  Hiroshima University

Nguyen PT, Tsunematsu T, Yanagisawa S, Kudo Y, Miyauchi M, Kamata N, Takata T   The FGFR-1 inhibitor PD173074 induces mesenchymal-epithelial transition through transcription factor AP-1   International conference

The 5th Hiroshima Conference on Education and Science in Dentistry   2013  Hiroshima University

Nguyen PT, Inubushi T, Tsunematsu T, Kudo Y, Kamata N, Ogawa I, Takata T   FGFR-1 inhibitor PD173074 induces mesenchymal-epithelial transition through suppression of AP-1 in Head and Neck squamous cell carcinoma   International conference

The 23rd Annual Meeting of the Japanese Society of Oral Pathology   2012  The Japanese Society of Oral Pathology

Nguyen PT, Inubushi T, Tsunematsu T, Kudo Y, Kamata N, Ogawa I, Takata T.   FGFR-1 inhibitor PD173074 induces mesenchymal-epithelial transition through suppression of AP-1 in Head and Neck squamous cell carcinoma   International conference

Mechanism & models of Cancer Meeting   2012  Cold Spring Harbor Laboratory

Ohbayashi M, Nguyen PT, Kudo Y, Yoshida M, Miyauchi M, Ogawa I, Takata T   N-cadherin expression is involved in malignant behavior of head and neck cancer in relation to epithelial-mesenchymal transition   International conference

The 15h International Congress on Oral Pathology and Medicine   2010  International Association of Oral and Maxillofacial Pathologists

Tomishima A, Nguyen PT, Shima K, Shimojukkoku Y, Sasahira T   The roles of MCTP2 in oral squamous cell carcinoma  

The 112th annual meeting of The Japanese Society Pathology  2023.4 

Nguyen PT, Shima K, Sasahira T   New insights into YAP nuclear translocation to promote liver tumorigenesis  

The 81st annual meeting of Japanese Cancer Association  2022.9 

Nguyen PT, Shima K, Shimojukkoku Y, Sasahira T   Impacts of KPNA7 amplification and overexpression on tumor infiltrating immune cells of HNSCCs  

The 112th annual meeting of The Japanese Society Pathology  2023.4 

Nguyen PT, Shima K, Shimojukkoku Y, Sasahira T   EPS8L3 mediates YAP nuclear translocation and promotes liver tumorigenesis.  

The 112th annual meeting of The Japanese Society Pathology  2023.4 

Oku Y, Nguyen PT, Shima K, Shimojukkoku Y, Sasahira T   Cytoplasmic TCF19 translocation impairs DNA damage repair in HNSCC.  

The 112th annual meeting of The Japanese Society Pathology  2023.4 

Shima K, Nguyen PT, Shimojukkoku Y, Sasahira T   Analysis of METTL5 expression and function in oral squamous cell carcinoma.  

The 112th annual meeting of The Japanese Society Pathology  2023.4 

下拾石 雄大, Phuong Thao NGUYEN, 嶋 香織, 石田喬之, 笹平智則   Functional analysis of EGR-1 as a tumor suppressor gene in oral squamous cell carcinoma  

第65回歯科基礎医学会  2023.9 

Kaori Shima, Phuong Thao Nguyen, Yudai Shimojukkoku, Tomonori Sasahira   Analysis of METTL5, a m6A methyltransferase, expression in oral squamous cell carcinoma  

第65回歯科基礎医学会  2023.9 

Thao Nguyen, Kaori Shima, Yudai Shimojukkoku, Yuka Kajiya, Tomonori Sasahira   Amplication of the nuclear import receptor KPNA7 is associated with poor overall survival in head and neck cancer  

第82回日本癌学会  2023.9 

EPS8L3 mediates YAP nuclear translocation and promotes liver tumorigenesis

Grant number：21K15401  2021.4 - 2024.3

Japan Society for the promotion of science  Grants-in-Aid for Scientific Research  Early Career Research

Periodontitis induced alterations of gut microbial metabolite promotes liver cancer through senescence

Grant number：19K18963  2019.4 - 2021.3

Japan Society for the promotion of science  Grants-in-Aid for Scientific Research  Early Career Research

NGUYEN THAO

Association of periodontitis and liver diseases

2017 - 2018

Hiroshima University 

Study on development of novel therapy targeting N-cadherin for oral cancer

2011.10 - 2013.10

Japan Society for the promotion of science