Updated on 2024/10/18

写真a

 
GODAI Kohei
 
Organization
University Hospital, Medical and Dental Sciences Area University Hospital Clinical Facilities Surgical Center Associate Professor
Title
Associate Professor

Degree

  • Doctor of Philosophy in Medical Science ( 2018.9   Kagoshima University )

Research Interests

  • Anesthesiology

  • Pain Clinic

  • Chronic Pain

Research Areas

  • Life Science / Anesthesiology  / Anesthesiology

  • Life Science / Neuroscience-general  / Pain Clinic, Chronic Pain, Glia

Education

  • Kagoshima University   Graduate School of Medical and Dental Sciences

    - 2018.9

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    Country: Japan

Research History

  • Kagoshima University   Kagoshima University Hospital, Operating Room   Lecturer

    2023.4

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    Country:Japan

  • Kagoshima University   Research Field in Medicine and Health Sciences, Medical and Dental Sciences Area Graduate School of Medical and Dental Sciences Advanced Therapeutics Course Functional Biology and Pharmacology   Assistant Professor

    2020.1 - 2023.3

  • Kagoshima University   Medical and Dental Hospital, Medical and Dental Sciences Area Medical and Dental Hospital Clinical Center Anesthesia and Critical Care Center   Assistant Professor

    2018.4 - 2019.12

Professional Memberships

  • Japanese Society of Anesthesiologists

    2010.4

  • Japan Society of Pain Clinicians

    2012.4

Committee Memberships

  • 日本麻酔科学会   第8麻酔全般ワーキンググループ サテライトメンバー  

    2023.3   

Studying abroad experiences

  • 2014.6 - 2016.5   University of Miami,   Research Scholar

Qualification acquired

  • 日本専門医機構認定麻酔科専門医

  • 日本ペインクリニック学会認定ペインクリニック専門医

  • Doctor

 

Papers

  • Onitsuka K, Godai K, Tanoue S, Sakurai E, Nakahara M, Koriyama C, Matsunaga A .  Incidence, outcomes, and risk factors of postlaparoscopic subcutaneous emphysema. .  Canadian Journal of Anesthesia   2024.10Incidence, outcomes, and risk factors of postlaparoscopic subcutaneous emphysema. Reviewed

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    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: https://doi.org/10.1007/s12630-024-02859-2

    Other Link: https://link.springer.com/article/10.1007/s12630-024-02859-2

  • Godai K, Moriyama T .  Heme oxygenase-1 in the spinal cord plays crucial roles in the analgesic effects of pregabalin and gabapentin in a spared nerve-injury mouse model. .  Neuroscience Letters767   136310   2021.10Reviewed

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    Authorship:Lead author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.neulet.2021.136310

    DOI: 10.1016/j.neulet.2021.136310

    Scopus

    PubMed

  • Godai K, Takahashi K, Kashiwagi Y, Liu CH, Yi H, Liu S, Dong C, Lubarsky DA, Hao S .  Ryanodine Receptor to Mitochondrial Reactive Oxygen Species Pathway Plays an Important Role in Chronic Human Immunodeficiency Virus gp120MN-Induced Neuropathic Pain in Rats. .  ANESTHESIA & ANALGESIA129 ( 1 ) 276 - 286   2018.11Ryanodine Receptor to Mitochondrial Reactive Oxygen Species Pathway Plays an Important Role in Chronic Human Immunodeficiency Virus gp120MN-Induced Neuropathic Pain in Rats.Reviewed

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:International Anesthesia Research Society  

    BACKGROUND:
    Chronic pain is one of the most common complaints in patients with human immunodeficiency virus (HIV)-associated sensory neuropathy. Ryanodine receptor (RyR) and mitochondrial oxidative stress are involved in neuropathic pain induced by nerve injury. Here, we investigated the role of RyR and mitochondrial superoxide in neuropathic pain induced by repeated intrathecal HIV glycoprotein 120 (gp120) injection.

    METHODS:
    Recombinant HIV glycoprotein gp120MN was intrathecally administered to induce neuropathic pain. Mechanical threshold was tested using von Frey filaments. Peripheral nerve fiber was assessed by the quantification of the intraepidermal nerve fiber density in the skin of the hindpaw. The expression of spinal RyR was examined using Western blots. Colocalization of RyR with neuronal nuclei (NeuN; neuron marker), glial fibrillary acidic protein (GFAP; astrocyte marker), or ionizing calcium-binding adaptor molecule 1 (Iba1; microglia marker) in the spinal cord was examined using immunohistochemistry. MitoSox-positive profiles (a mitochondrial-targeted fluorescent superoxide indicator) were examined. The antiallodynic effects of intrathecal administration of RyR antagonist, dantrolene (a clinical drug for malignant hyperthermia management), or selective mitochondrial superoxide scavenger, Mito-Tempol, were evaluated in the model.

    RESULTS:
    We found that repeated but not single intrathecal injection of recombinant protein gp120 induced persistent mechanical allodynia. Intraepidermal nerve fibers in repeated gp120 group was lower than that in sham at 2 weeks, and the difference in means (95% confidence interval) was 8.495 (4.79-12.20), P = .0014. Repeated gp120 increased expression of RyR, and the difference in means (95% confidence interval) was 1.50 (0.504-2.495), P = .007. Repeated gp120 also increased mitochondrial superoxide cell number in the spinal cord, and the difference in means (95% confidence interval) was 6.99 (5.99-8.00), P < .0001. Inhibition of spinal RyR or selective mitochondrial superoxide scavenger dose dependently reduced mechanical allodynia induced by repeated gp120 injection. RyR and mitochondrial superoxide were colocalized in the neuron, but not glia. Intrathecal injection of RyR inhibitor lowered mitochondrial superoxide in the spinal cord dorsal horn in the gp120 neuropathic pain model.

    CONCLUSIONS:
    These data suggest that repeated intrathecal HIV gp120 injection induced an acute to chronic pain translation in rats, and that neuronal RyR and mitochondrial superoxide in the spinal cord dorsal horn played an important role in the HIV neuropathic pain model. The current results provide evidence for a novel approach to understanding the molecular mechanisms of HIV chronic pain and treating chronic pain in patients with HIV.

    DOI: 10.1213/ANE.0000000000003916

    PubMed

  • Godai K, Kanmura Y .  Heme oxygenase-1 inducer and carbon monoxide-releasing molecule enhance the effects of gabapentinoids by modulating glial activation during neuropathic pain in mice. .  PAIN Reports3 ( 5 ) e677   2018.8Reviewed

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:International Association for the Study of Pain  

    DOI: 10.1097/PR9.0000000000000677

    Scopus

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  • Godai K, Hasegawa-Moriyama M, Matsunaga A, Kanmura Y .  Phenylephrine does not improve oxygenation during one-lung ventilation: A randomized, double-blind, cross-over study .  PLOS ONE   2018.4Phenylephrine does not improve oxygenation during one-lung ventilation: A randomized, double-blind, cross-over studyReviewed

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1371/journal.pone.0195576

    PubMed

  • Godai K, Moriyama T, Kanmura Y .  Comparison of the MultiViewScope Stylet Scope and the direct laryngoscope with the Miller blade for the intubation in normal and difficult pediatric airways: A randomized, crossover, manikin study. .  PLoS One15 ( 8 ) e0237593   2020.8Reviewed

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:PLoS ONE  

    Abstract
    Background
    Managing difficult pediatric airway is challenging. The MultiViewScope (MVS) Stylet Scope is reported to be useful in difficult pediatric airway. In this randomized crossover study, we compared the effectiveness of the MVS Stylet Scope to a standard direct laryngoscope with Miller #1 blade in simulated normal and difficult airways.

    Methods
    Fifteen expert anesthesiologists and Fifteen anesthesiology residents participated in the study. Participants were asked to perform intubation with the Airsim Baby manikin first, and then with the Airsim Pierre Robin manikin. Participants in each group used the intubation devices in a randomized order. The primary outcome was the time of successful intubation. The secondary outcomes were the force exerted on the incisors during intubation, Cormack–Lehane scale, the difficulty of intubation.

    Results
    There were no differences between MVS Stylet Scope and Direct laryngoscope in the time of successful intubation by the expert anesthesiologists or the anesthesiology residents in a normal or difficult pediatric airway. MVS Stylet Scope significantly improved the force exerted on the incisors during intubation in the expert anesthesiologists or the anesthesiology residents in a normal or difficult pediatric airway. MVS Stylet Scope significantly improved Cormack–Lehane scale, and the difficulty of intubation with difficult pediatric airway situation in both expert anesthesiologists and anesthesiology residents.

    Conclusions
    Although less forces on the incisors and improved view of glottis were observed with the MVS Stylet Scope, MVS Stylet Scope did not shorten the time of intubation. The results of this study mean that the MVS Stylet Scope may be a less invasive airway devise than the direct laryngoscope with the Miller blade in the pediatric airway management. For the next step, we need to evaluate the MVS Stylet Scope in the real patients as an observational study.

    DOI: 10.1371/journal.pone.0237593

    Scopus

    PubMed

    Other Link: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0237593

  • Godai K, Matsunaga A, Kanmura Y .  The effects of hemodynamic management using the trend of the perfusion index and pulse pressure variation on tissue perfusion: a randomized pilot study. .  JA Clinical Reports5 ( 1 ) 72   2019.11The effects of hemodynamic management using the trend of the perfusion index and pulse pressure variation on tissue perfusion: a randomized pilot study.Reviewed

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:the Japanese Society of Anesthesiologists  

    Background
    Intraoperative hemodynamic management is challenging because precise assessment of the adequacy of the intravascular volume is difficult during surgery. Perfusion index (PI) has been shown to reflect changes in peripheral circulation perfusion. Pulse pressure variation (PPV) reflects the preload responsiveness. The hypothesis of this study was that hemodynamic management using the trend of the PI and PPV would improve tissue perfusion.

    Methods
    This was a prospective, randomized, parallel design, single-blind, single-center pilot study. Patients undergoing elective open gynecological surgery requiring a direct arterial line were included. The patients were randomly allocated to two groups. The intervention group received hemodynamic management using the trend of the PI and PPV in an effort to improve tissue perfusion. The control group received hemodynamic management at the discretion of the anesthesia care provider. The primary outcome was the peak lactate level during surgery. The secondary outcomes were the duration of hypotension, intraoperative fluid balance, intraoperative urine output, and postoperative complication rate. Statistical analysis was performed using Student’s t test and Fisher’s exact test. A P value of < 0.05 was considered statistically significant.

    Results
    Although the intervention significantly decreased the duration of hypotension and intraoperative fluid balance, the peak lactate level was not different between the intervention group and the control group. Intraoperative urine output and postoperative complication rate were not different between the groups.

    Conclusion
    Hemodynamic management using the trend of the PI and PPV does not improve tissue perfusion in patients undergoing open gynecological surgery.

    Trial registration
    This trial was prospectively registered on a publicly accessible database (UMIN Clinical Trials Registry ID: UMIN 000026957. Registered 12 April 2017, https://upload.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000030916).

    DOI: 10.1186/s40981-019-0291-5

    PubMed

    Other Link: https://jaclinicalreports.springeropen.com/articles/10.1186/s40981-019-0291-5

  • Godai K, Hasegawa-Moriyama M, Kurimoto T, Saito T, Yamada T, Sato T, Kojima M, Kanmura Y .  Peripheral administration of morphine attenuates postincisional pain by regulating macrophage polarization through COX-2-dependent pathway .  Molecular Pain   2014.1Peripheral administration of morphine attenuates postincisional pain by regulating macrophage polarization through COX-2-dependent pathwayReviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1186/1744-8069-10-36

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  • Godai K, Hasegawa-Moriyama M, Kuniyoshi T, Matsunaga A, Kanmura Y .  Increased carboxyhemoglobin level during liver resection with inflow occlusion .  Journal of Anesthesia   2012.11Increased carboxyhemoglobin level during liver resection with inflow occlusionReviewed

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:日本麻酔科学会  

    DOI: 10.1007/s00540-012-1513-4

    PubMed

  • Hasegawa-Moriyama M, Kuniyoshi T, Nakama M, Godai K, Kojima M, Kuwaki T, Kanmura Y .  Peroxisome proliferator-activated receptor-gamma agonist rosiglitazone attenuates inflammatory pain through the induction of heme oxygenase-1 in macrophages .  PAIN   2013.4Peroxisome proliferator-activated receptor-gamma agonist rosiglitazone attenuates inflammatory pain through the induction of heme oxygenase-1 in macrophagesReviewed

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:International Association for the Study of Pain  

    DOI: 10.1016/j.pain.2013.04.039

    PubMed

  • Hasegawa-Moriyama M, Ohnou T, Godai K, Kurimoto T, Nakama M, Kanmura Y .  Peroxisome proliferator-activated receptor-gamma agonist rosiglitazone attenuates postincisional pain by regulating macrophage polarization .  Biochemical and Biophysical Research Communications   2012.8Peroxisome proliferator-activated receptor-gamma agonist rosiglitazone attenuates postincisional pain by regulating macrophage polarizationReviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.bbrc.2012.08.039

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  • Kuroki C, Godai K, Hasegawa-Moriyama M, Kuniyoshi T, Matsunaga A, Kanmura Y, Kuwaki T .  Perfusion index as a possible predictor for postanesthetic shivering .  Journal of Anesthesia   2013.6Perfusion index as a possible predictor for postanesthetic shiveringReviewed

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:日本麻酔科学会  

    DOI: 10.1007/s00540-013-1658-9

    PubMed

  • Godai K .  Anaesthesia recommendations for Schwartz-Jampel syndrome. .  Anesthesiology & Intensive care64   S313 - S318   2023.9Reviewed

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    Authorship:Lead author   Language:English   Publishing type:Research paper (other academic)  

    DOI: 10.19224/ai2023.S313

    Scopus

  • Hagihara S, Abe Y, Godai K, Kamijima K, Enohata K, and Matsunaga A .  Successful neurolytic thoracic sympathetic ganglion block using C-arm fluoroscopic cone-beam computed tomography in patients with postmastectomy pain syndrome: a report of 3 cases. .  JA Clinical Reports9   48   2023.8Reviewed

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    Language:English   Publishing type:Research paper (other academic)  

    DOI: https://doi.org/10.1186/s40981-023-00639-3

  • 榎畑京, 五代幸平, 萩原信太郎 .  X線透視・超音波二重ガイド下仙腸関節枝高周波熱凝固が有用だった仙腸関節症の2症例. .  ペインクリニック44 ( 1 ) 72 - 75   2023.1X線透視・超音波二重ガイド下仙腸関節枝高周波熱凝固が有用だった仙腸関節症の2症例.Reviewed

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    Language:Japanese   Publishing type:Research paper (other academic)  

  • Hagihara S, Nakagawa M, Matsubara K, Godai K, Kamijima K, Abe Y .  Successful annuloplasty using the cone-beam computed tomography-assisted radiofrequency thermocoagulation system in a patient with severe vertebral deformity: a case report. .  JA clinical reports8 ( 1 ) 63   2022.8Successful annuloplasty using the cone-beam computed tomography-assisted radiofrequency thermocoagulation system in a patient with severe vertebral deformity: a case report.Reviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1186/s40981-022-00554-z

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  • Godai K .  Anaesthesia recommendations for Pallister-Hall syndrome. .  Anesthesiology & Intensive care63   S242 - S247   2022.7Reviewed

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    Authorship:Lead author   Language:English   Publishing type:Research paper (other academic)  

    DOI: 10.19224/ai2022.S242

    Scopus

  • Tashiro S. .  Successful intrathecal neurolytic block for the management of cancer pain in a 10-year-old child: a case report .  JA Clinical Reports7 ( 1 ) 33   2021.12Reviewed

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    Publisher:JA Clinical Reports  

    DOI: 10.1186/s40981-021-00438-8

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  • Mukaihara K, Godai K, Moriyama T .  Tracheal varicose veins associated with Klippel-Trenaunay syndrome .  Anesthesiology135   1121   2021.10Tracheal varicose veins associated with Klippel-Trenaunay syndromeReviewed

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    Authorship:Corresponding author   Language:English  

    DOI: 10.1097/ALN.0000000000004016

  • Godai K .  Blood pressure, one of the most important factors is missing in the analysis of the association between intraoperative oliguria and acute kidney injury. .  ANESTHESIA & ANALGESIA128   e81   2019.5Blood pressure, one of the most important factors is missing in the analysis of the association between intraoperative oliguria and acute kidney injury.Reviewed

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:International Anesthesia Research Society  

    DOI: 10.1213/ANE.0000000000004081

  • Godai K .  Comment on “Schwartz–Jampel syndrome: Is risk of malignant hyperthermia the same as that of the general population? .  Saudi Journal of Anaesthesia13 ( 2 ) 147 - 148   2019.3Comment on “Schwartz–Jampel syndrome: Is risk of malignant hyperthermia the same as that of the general population?Reviewed

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:Saudi Anaesthetic Association  

    DOI: 10.4103/sja.SJA_650_18

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  • Godai K, Hasegawa-Moriyama M, Matsunaga A, Kanmura Y .  Phenylephrine does not improve oxygenation during one-lung ventilation: A randomized, double-blind, cross-over study. .  PLoS ONE   2018.9Phenylephrine does not improve oxygenation during one-lung ventilation: A randomized, double-blind, cross-over study. Reviewed

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    Language:English   Publishing type:Doctoral thesis  

    DOI: 10.1371/journal.pone.0195576

  • Matsuo K, Godai K, and Kanmura Y .  Anesthetic management of meningioma resection under motor evoked potential monitoring in a patient with a history of propofol infusion syndrome .  The Japanese Journal of Anesthesiology   2018.6Anesthetic management of meningioma resection under motor evoked potential monitoring in a patient with a history of propofol infusion syndromeReviewed

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

  • Oe Y, Godai K, Masuda M, Kanmura Y .  Difficult airway associated with bifid glottis and coexistent subglottic stenosis in a patient with Pallister-Hall Syndrome: A case report .  JA Clinical Reports4 ( 1 ) 20   2018.2Difficult airway associated with bifid glottis and coexistent subglottic stenosis in a patient with Pallister-Hall Syndrome: A case reportReviewed

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:日本麻酔科学会  

    DOI: 10.1186/s40981-018-0158-1

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  • Godai K .  Anaesthesia recommendations for patients suffering from Miller-Dieker syndrome .  Anästhesiologie & Intensivmedizin58 ( 10 ) S591 - S596   2017.10Reviewed

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:Anasthesiologie und Intensivmedizin  

    DOI: 10.19224/ ai2017.S591

    Scopus

  • Godai K .  Schwartz–Jampel syndrome is not related to malignant hyperthermia .  JA Clinical Reports3 ( 1 ) 32   2017.6Schwartz–Jampel syndrome is not related to malignant hyperthermiaReviewed

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:日本麻酔科学会  

    DOI: 10.1186/s40981-017-0104-7

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  • Godai K .  Ultra-low dose spinal anaesthesia for hip fracture surgery .  Anaesthesia   2016.12Ultra-low dose spinal anaesthesia for hip fracture surgeryReviewed

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/anae.13770

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  • Mukaihara K, Godai K, Yamada T, Hasegawa-Moriyama M, Kanmura Y .  Successful airway management using a MultiViewScope handle with a stylet scope in a patient with Schwartz–Jampel Syndrome .  JA Clinical Reports   2016.11Successful airway management using a MultiViewScope handle with a stylet scope in a patient with Schwartz–Jampel SyndromeReviewed

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:日本麻酔科学会  

    DOI: 10.1186/s40981-016-0062-5

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  • Godai K, Tashiro S, Kiyonaga N, Sonoda T, Ohnou T, Kanmura Y .  A patient with adhesive capsulitis, who described upper limb pain with radiation to forearm .  Journal of Japan Society of Pain Clinicians   2016.11A patient with adhesive capsulitis, who described upper limb pain with radiation to forearmReviewed

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    Authorship:Lead author   Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:Japan Society of Pain Clinicians  

    DOI: 10.11321/jjspc.16-0010

  • Nagamine Y, Godai K, Oki H, Kanmura Y .  Management of a centenarian who underwent emergency laparoscopic cholecystectomy under general anesthesia with subcostal transversus abdominis plane block .  JA Clinical Reports   2016.9Management of a centenarian who underwent emergency laparoscopic cholecystectomy under general anesthesia with subcostal transversus abdominis plane blockReviewed

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:日本麻酔科学会  

    DOI: 10.1186/s40981-016-0050-9

  • Hasegawa-Moriyama M, Godai K, Yamada T, Matsunaga A, Kanmura Y .  Ligation of the internal jugular vein increased regional cerebral oxygen saturation but decreased the bispectral index in a 72-year-old man: a case report. .  JA Clinical Reports   2016.1Ligation of the internal jugular vein increased regional cerebral oxygen saturation but decreased the bispectral index in a 72-year-old man: a case report.Reviewed

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:日本麻酔科学会  

    DOI: 10.1186/s40981-015-0027-0

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  • Wakiguchi C, Godai K, Mukaihara K, Ohnou T, Kuniyoshi T, Masuda M, Kanmura Y .  Management of general anesthesia in a child with Miller–Dieker syndrome: a case report .  JA Clinical Reports   2015.9Management of general anesthesia in a child with Miller–Dieker syndrome: a case reportReviewed

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    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:日本麻酔科学会  

    DOI: 10.1186/s40981-015-0017-2

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  • Godai K .  Carbon monoxide has antinociceptive effects in rodent models of pain .  Pediatric Anesthesia   2015.4Carbon monoxide has antinociceptive effects in rodent models of painReviewed

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/pan.12638

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  • Godai K*, Hasegawa-Moriyama M, Unoki K, Uchida Y, Kuniyoshi T, Matsunaga A, Kanmura Y .  Suspected intraoperative formation of left atrial thrombus in a patient with atrial fibrillation receiving bridging anticoagulation therapy .  Journal of Anesthesia   2013.1Suspected intraoperative formation of left atrial thrombus in a patient with atrial fibrillation receiving bridging anticoagulation therapyReviewed

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:日本麻酔科学会  

    DOI: 10.1007/s00540-013-1664-y

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  • Godai K, Hasegawa-Moriyama M, Masuda M, Matsunaga A, Isowaki S, Kanmura Y .  Rapid development of airway edema during tracheal intubation in a patient with Kniest dysplasia .  Anesthesia and Resuscitation   2012.6Rapid development of airway edema during tracheal intubation in a patient with Kniest dysplasiaReviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

  • Godai K, Hasegawa-Moriyama M, Kuniyoshi T, Kakoi T, Ikoma K, Isowaki S, Matsunaga A, Kanmura Y .  Three cases of suspected sugammadex-induced hypersensitivity reactions .  British Journal of Anaesthesia   2012.5Three cases of suspected sugammadex-induced hypersensitivity reactionsReviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1093/bja/aes137

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Books

  • Life Support and Anesthesia Vol.31 No.8

    ( Role: Contributor)

    2024.8 

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    Responsible for pages:735-7   Language:Japanese Book type:Scholarly book

  • Q&A循環管理:麻酔科専門医が答える74の疑問

    五代幸平( Role: Joint author ,  第Ⅳ章 肝臓 1. 肝血流 Q1. 肝血流の調節は?)

    克誠堂  2024.6  ( ISBN:978-4-7719-0588-7

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    Total pages:183   Responsible for pages:56-8   Language:Japanese Book type:Textbook, survey, introduction

  • Q&A循環管理:麻酔科専門医が答える74の疑問

    五代幸平( Role: Joint author ,  第Ⅳ章 肝臓 1. 肝血流 Q2. 肝血流に対する麻酔薬の影響は?)

    克誠堂  2024.6  ( ISBN:978-4-7719-0588-7

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    Total pages:183   Responsible for pages:58-9   Language:Japanese Book type:Textbook, survey, introduction

  • Q&A循環管理:麻酔科専門医が答える74の疑問

    五代幸平( Role: Joint author ,  第Ⅳ章 肝臓 1. 肝血流 Q3. 肝血流の測定法は?)

    克誠堂  2024.6  ( ISBN:978-4-7719-0588-7

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    Total pages:183   Responsible for pages:59-61   Language:Japanese Book type:Textbook, survey, introduction

  • Life Support and Anesthesia Vol.30 No.11

    ( Role: Contributor)

    2023.11 

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    Responsible for pages:1181-217   Language:Japanese Book type:Scholarly book

  • Life Support and Anesthesia Vol.30 No.9

    ( Role: Contributor)

    2023.9 

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    Responsible for pages:925-47   Language:Japanese Book type:Scholarly book

  • Life Support and Anesthesia Vol.30 No.8

    ( Role: Contributor)

    2023.8 

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    Responsible for pages:831-4   Language:Japanese Book type:Scholarly book

  • Life Support and Anesthesia Vol.30 No.4

    ( Role: Contributor)

    2023.4 

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    Responsible for pages:456-9   Language:Japanese Book type:Scholarly book

  • Life Support and Anesthesia Vol.30 No.3

    ( Role: Contributor)

    2023.3 

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    Responsible for pages:312-5   Language:Japanese Book type:Scholarly book

  • Life Support and Anesthesia Vol.30 No.2

    ( Role: Contributor)

    2023.2 

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    Responsible for pages:229-30   Language:Japanese Book type:Scholarly book

  • Life Support and Anesthesia Vol.29 No.11

    ( Role: Contributor)

    2022.11 

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    Responsible for pages:1104-1107   Language:Japanese Book type:Scholarly book

  • Life Support and Anesthesia Vol.29 No.4

    Harimochi S, Godai K( Role: Contributor)

    2022.4 

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    Responsible for pages:316-318   Language:Japanese Book type:Scholarly book

  • 研修医になったら必ずこの手技を身に付けてください。改訂版

    五代幸平( Role: Contributor ,  第1章. 注射、採血、穿刺のこれだけは身につけてください。5. 動脈採血. )

    羊土社  2022.4  ( ISBN:978-4-7581-2389-1

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    Responsible for pages:49-55   Language:Japanese Book type:Scholarly book

  • OGS NOW basic No.4 Let's Start Benign Tumor Surgery from Tomorrow: for Beginners and Mentors

    Godai Kohei, Kanmura Yuichi( Role: Joint author ,  Anesthesia for gynecologic benign tumor surgery)

    Medical View CO., Ltd.  2020.12 

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    Total pages:160   Responsible for pages:18-27   Language:Japanese Book type:Scholarly book

  • LiSA 周術期管理を核とした総合誌[リサ] Life Support and Anesthesia Vol.26 No.12 (12月号)

    五代 幸平( Role: Contributor ,  症例カンファレンス: 統合失調症と肥満がある妊婦の予定帝王切開術, 症例提示, キーポイント解説, 本症例における周術期管理の実際)

    メディカル・サイエンス・インターナショナル  2019.12 

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    Responsible for pages:1191-3, 1206-9   Language:Japanese Book type:Scholarly book

  • LiSA 周術期管理を核とした総合誌[リサ] Life Support and Anesthesia Vol.26 No.5 (5月号)

    五代 幸平( Role: Contributor ,  症例カンファレンス: 左不全麻痺を有する認知症患者の骨接合術, 症例提示, キーポイント解説, 本症例における周術期管理の実際)

    メディカル・サイエンス・インターナショナル  2019.5 

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    Responsible for pages:415-7, 428-30   Language:Japanese Book type:Scholarly book

  • 麻酔科研修ノート 改訂第3版

    五代幸平( Role: Contributor)

    診断と治療社  2018.12 

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    Responsible for pages:546-9   Language:Japanese Book type:Scholarly book

  • LiSA 周術期管理を核とした総合誌[リサ] Life Support and Anesthesia Vol.25 No.4 (4月号).

    五代幸平( Role: Contributor ,  症例カンファレンス: 気管支喘息とコントロール不良の甲状腺機能亢進症を有する卵巣癌患者, PLAN3: 原疾患や合併症のみに着眼せず 患者をトータルにとらえよう)

    メディカル・サイエンス・インターナショナル  2018.4 

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    Responsible for pages:185-187   Language:Japanese Book type:Scholarly book

  • 麻酔偶発症AtoZ

    五代幸平, 上村裕一( Role: Contributor ,  1. 全身麻酔 2) 肺・縦隔手術および呼吸器系偶発症 a. 診療科特有のもの. 肺水腫)

    文光堂  2017.6 

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    Responsible for pages:88-89   Language:Japanese Book type:Scholarly book

  • 麻酔偶発症AtoZ

    五代幸平, 上村裕一( Role: Contributor ,  1. 全身麻酔 5) 腹腔鏡下手術の偶発症 a. 診療科特有のもの. 腹壁膿瘍)

    文光堂  2017.6 

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    Responsible for pages:152-153   Language:Japanese Book type:Scholarly book

  • 研修医になったら必ずこの手技を身に付けてください。

    五代幸平( Role: Contributor ,  第1章. 注射、採血、穿刺のこれだけは身につけてください。5. 動脈採血. )

    羊土社  2017.4 

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    Responsible for pages:49-56   Language:Japanese Book type:Scholarly book

  • LiSA 麻酔を核とした総合誌[リサ] Life Support and Anesthesia Vol.24 No.3 (3月号)

    五代幸平( Role: Contributor ,  腎動脈近位の腹部大動脈瘤手術)

    メディカル・サイエンス・インターナショナル  2017.3 

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    Responsible for pages:256-160   Language:Japanese Book type:Scholarly book

  • 気道管理の疑問 Q&A 70

    五代幸平( Role: Contributor ,  Q58. 手術中に酸素飽和度が低下したら何を疑うべきでしょうか?またどのように対処すればよいですか?)

    中外医学社  2016.11 

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    Responsible for pages:177-179   Language:Japanese Book type:Scholarly book

  • 気道管理の疑問 Q&A 70

    五代幸平( Role: Contributor ,  Q60. 手術中に気道内圧が低下したら何を疑いますか?対処法についても教えてください.)

    中外医学社  2016.11 

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    Responsible for pages:182-183   Language:Japanese Book type:Scholarly book

  • 気道管理の疑問 Q&A 70

    五代幸平( Role: Contributor ,  Q59. 手術中に気道内圧が上昇したら何を考えますか?どう対処すればよいでしょうか?)

    中外医学社  2016.11 

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    Responsible for pages:180-181   Language:Japanese Book type:Scholarly book

  • 新・麻酔科研修の素朴な疑問に答えます

    五代幸平( Role: Contributor ,  047. 臓器血流の自己調節メカニズムはどのようなものか?)

    メディカル・サイエンス・インターナショナル  2016.9 

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    Responsible for pages:147-150   Language:Japanese Book type:Scholarly book

  • LiSA 麻酔を核とした総合誌[リサ] Life Support and Anesthesia Vol.23 No.8 (8月号)

    五代幸平( Role: Contributor ,  ようこそマイアミへ!)

    メディカル・サイエンス・インターナショナル  2016.8 

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    Responsible for pages:694-965   Language:Japanese Book type:Scholarly book

  • 麻酔科クリニカルクエスチョン101

    五代幸平, 松永明( Role: Contributor ,  Q12 モニター心電図はどのような誘導を用いるべきか?)

    診断と治療社  2016.5 

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    Responsible for pages:27-28   Language:Japanese Book type:Scholarly book

  • 麻酔科クリニカルクエスチョン101

    五代幸平, 松永明( Role: Contributor ,  Q15 動脈カテーテルの合併症にはどのようなものがあるか?)

    診断と治療社  2016.5 

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    Responsible for pages:33-34   Language:Japanese Book type:Scholarly book

  • LiSA 麻酔を核とした総合誌[リサ] Life Support and Anesthesia Vol.21 No.10 (10月号).

    五代幸平, 松永明( Role: Contributor ,  臓器血流の自己調節メカニズム)

    メディカル・サイエンス・インターナショナル  2014.10 

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    Responsible for pages:960-961   Language:Japanese Book type:Scholarly book

  • LiSA 麻酔を核とした総合誌[リサ] Life Support and Anesthesia Vol.21 No.10 (10月号).

    五代幸平, 松永明( Role: Contributor ,  自己調節能がある臓器とない臓器の違いは何か)

    メディカル・サイエンス・インターナショナル  2014.10 

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    Responsible for pages:962-963   Language:Japanese Book type:Scholarly book

  • LiSAコレクション症例で学ぶ新しい周術期の輸液管理

    五代幸平( Role: Contributor ,  総論2. 輸液管理とアウトカム)

    メディカル・サイエンス・インターナショナル  2014.8 

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    Responsible for pages:14-19   Language:Japanese Book type:Scholarly book

  • レジデントノート Vol.16 No.1 (4月号)

    五代幸平( Role: Contributor ,  動脈採血の基本とトラブルシューティング. )

    羊土社  2014.4 

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    Responsible for pages:37-44   Language:Japanese Book type:Scholarly book

  • LiSA collection, Ultrasound-guided Peripheral Nerve Blocks in 24 cases

    ( Role: Contributor ,  Case 22, Caudal blocks in patients undergoing orchiopexy)

    Medical Science International  2013.5 

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MISC

  • 最新の術中輸液管理:術中循環管理に関連する最新の知見 Invited

    五代幸平

    外科と代謝・栄養   58 ( 4 )   104 - 108   2024.8

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    Authorship:Lead author, Corresponding author   Language:Japanese  

  • Current understanding of the mechanism for postoperative pain

    Kohei Godai

    Pain Clinic   15 ( 8 )   1027 - 1034   2020.8

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media)   Publisher:Shinko Trading Company Ltd., Publication Department of Medical Books  

Presentations

  • Kohei Godai   Calcium channel α2δ ligands, from basic research to clinical applications   Invited International conference

    37th scientific meeting of The Pain Society of Busan⋅Ulsan⋅Kyungnam (BUK-Pain)  2019.8  The Pain Society of Busan⋅Ulsan⋅Kyungnam

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    Event date: 2019.8

    Language:English   Presentation type:Oral presentation (invited, special)  

    Venue:Busan   Country:Korea, Republic of  

  • 五代幸平   レミマゾラムの効果的な使い方ー非エキスパートでTIVA好きな麻酔科医の場合ーレミマゾラムの上手な使い方   Invited

    全身麻酔領域WEBセミナー  2024.6  ムンディファーマ株式会社

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    Event date: 2024.6

    Language:Japanese   Presentation type:Public lecture, seminar, tutorial, course, or other speech  

    Country:Japan  

  • 五代幸平   レミマゾラムの上手な使い方   Invited

    第34回九州歯科麻酔シンポジウム  2024.2  日本歯科麻酔学会

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    Event date: 2024.2

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Venue:鹿児島   Country:Japan  

  • 五代幸平   末梢性神経障害性疼痛のメカニズムーミクログリアに着目してー   Invited

    日本麻酔科学会 第69回学術集会  2022.6  日本麻酔科学会

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    Event date: 2022.6

    Language:Japanese   Presentation type:Symposium, workshop panel (nominated)  

    Venue:神戸  

  • 五代 幸平   その痛み我慢しないでください~ペインクリニックという選択肢~   Invited

    第2回三星会(鹿屋高校同窓会)医療部会  2017.8  三星会(鹿屋高校同窓会)医療部会

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    Event date: 2017.8

    Language:Japanese   Presentation type:Public lecture, seminar, tutorial, course, or other speech  

    Venue:鹿児島県鹿屋市   Country:Japan  

  • 五代 幸平   海外に目を向けよう:研究留学のススメ Let's research abroad!   Invited

    日本麻酔科学会 第63回学術集会  2016.5  日本麻酔科学会

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    Event date: 2016.5

    Language:Japanese   Presentation type:Symposium, workshop panel (nominated)  

    Venue:福岡   Country:Japan  

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Awards

  • Best Reviewers in Journal of Anesthesia

    2024.6   Japanese Society of Anesthesiologists  

    Kohei Godai

  • Best Reviewers in JA Clinical Reports

    2024.6   Japanese Society of Anesthesiologists  

    Kohei Godai

  • 第39回日本循環制御医学会総会会長賞

    2019.6   日本循環制御医学会   巨大前縦隔腫瘍により気管分岐部を圧排し起座呼吸をきたした症例に対する全身麻酔下心タンポナーデ解除術の経験

    五代幸平, 松尾敬介, 馬場敬太, 大納哲也, 上村裕一

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    Award type:Award from Japanese society, conference, symposium, etc.  Country:Japan

    第39回日本循環制御医学会総会における学会賞・セッション 症例報告(1)の部

Research Projects

  • Caチャネルα2δリガンドのHO-1/グリア細胞を介した鎮痛機序の解明

    2023.4 - 2026.3

    科学研究費補助金  基盤研究(C)

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    Authorship:Principal investigator 

    神経障害性疼痛治療薬は慢性痛患者では鎮痛効果が現れるのに数日を要するのに対して、神経障害性疼痛モデル動物においては投与後1時間程度で鎮痛効果を認める。そのため、神経損傷の急性期と慢性期の違いにより疼痛メカニズムが異なっている可能性がある。神経障害性疼痛の慢性期において急性期に認められる脊髄後角のミクログリア集積とα2δサブユニットの発現増加がどのように変化し、その変化がα2δリガンドや三環系抗うつ薬、SNRIといった神経障害性疼痛治療薬の鎮痛効果にもたらす影響を明らかとする。

  • Do the mechanisms of pain change in the spinal dorsal horn during chronic phase of neuropathic pain?

    2020.4 - 2023.3

    Grant-in-Aid for Scientific Research  Grant-in-Aid for Early-Career Scientists

  • 慢性疼痛における痛覚伝導路でのヘム・オキシゲナーゼの鎮痛・発痛効果の検討

    2017.4 - 2020.3

    科学研究費補助金  若手研究(B)

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    本研究は慢性痛におけるヘム・オキシゲナーゼ-1 (HO-1)及びヘム・オキシゲナーゼ-2 (HO-2)の鎮痛もしくは発痛作用を、痛覚の伝導路である脊髄後角・後根神経節・末梢神経において解明するものである。