Updated on 2024/03/26

写真a

 
TAGAWA Yoshiaki
 
Organization
Research Field in Medicine and Health Sciences, Medical and Dental Sciences Area Graduate School of Medical and Dental Sciences Advanced Therapeutics Course Neurology Professor
Title
Professor
External link

Degree

  • 博士(医学)(京都大学) ( 1999.7   京都大学 )

Research Interests

  • Neuroscience

Research Areas

  • Life Science / Neuroscience-general

Education

  • Kyoto University

    1994.4 - 1997.11

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    Country: Japan

  • Kyoto University

    1988.4 - 1994.3

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    Country: Japan

Professional Memberships

  • 日本生理学会

    2017.7

  • 日本神経科学会

    2004.4

  • 北米神経科学会(Society for Neuroscience)

    1999.4

Studying abroad experiences

  • 2000.10 - 2004.2   アメリカハーバード大学(Harvard Medical School)   研究員

Qualification acquired

  • Doctor

 

Papers

  • Yuta Tezuka†, Kenta M Hagihara†, Kenichi Ohki, Tomoo Hirano, Yoshiaki Tagawa .  Developmental stage-specific spontaneous activity contributes to callosal axon projections .  eLife11 ( e72435 ) 1 - 15   2022.8Developmental stage-specific spontaneous activity contributes to callosal axon projectionsReviewed

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    Authorship:Last author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: https://doi.org/10.7554/eLife.72435

  • Nao Nakagawa-Tamagawa, Emi Kirino, Kohtaroh Sugao, Hidetaka Nagata, Yoshiaki Tagawa .  Involvement of Calcium-Dependent Pathway and β Subunit-Interaction in Neuronal Migration and Callosal Projection Deficits Caused by the Cav1.2 I1166T Mutation in Developing Mouse Neocortex .  Frontiers in Neuroscience15 ( 747951 ) 1 - 13   2021.12Reviewed

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    Authorship:Last author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: https://doi.org/10.3389/fnins.2021.747951

  • Kenta M Hagihara, Ayako Wendy Ishikawa, Yumiko Yoshimura, Yoshiaki Tagawa, Kenichi Ohki .  Long-Range Interhemispheric Projection Neurons Show Biased Response Properties and Fine-Scale Local Subnetworks in Mouse Visual Cortex .  Cerebral Cortex31 ( 2 ) 1307 - 1315   2021.1Invited Reviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1093/cercor/bhaa297

    Scopus

    PubMed

    Other Link: https://pubmed.ncbi.nlm.nih.gov/33063102/

  • Bando Y, Irie K, Shimomura T, Umeshima H, Kushida Y, Kengaku M, Fujiyoshi Y, Hirano T, & Tagawa Y. .  Control of spontaneous Ca2+ transients is critical for neuronal maturation in the developing neocortex. .  Cerebral Cortex26 ( 1 ) 106 - 117   2016.1Control of spontaneous Ca2+ transients is critical for neuronal maturation in the developing neocortex.Reviewed

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1093/cercor/bhu180

    PubMed

  • Hagihara KM, Murakami T, Yoshida T, Tagawa Y, Ohki K. .  Neuronal activity is not required for the initial formation and maturation of visual selectivity. .  Nature Neuroscience18 ( 12 ) 1780 - 1788   2015.12Neuronal activity is not required for the initial formation and maturation of visual selectivity.Reviewed

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1038/nn.4155

    PubMed

  • Bando Y, Hirano T, Tagawa Y. .  Dysfunction of KCNK potassium channels impairs neuronal migration in the developing mouse cerebral cortex. .  Cerebral Cortex24 ( 4 ) 1017 - 1029   2014.4Dysfunction of KCNK potassium channels impairs neuronal migration in the developing mouse cerebral cortex. Reviewed

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1093/cercor/bhs387

    PubMed

  • Hayashi Y, Tagawa Y, Yawata S, Nakanishi S, Funabiki K. .  Spatio-temporal control of neural activity in vivo using fluorescence microendoscopy. .  European Journal of Neuroscience36 ( 6 ) 2722 - 2732   2012.9Spatio-temporal control of neural activity in vivo using fluorescence microendoscopy.Reviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/j.1460-9568.2012.08191.x

    PubMed

  • Mizuno H, Hirano T, Tagawa Y. .  Pre-synaptic and post-synaptic neuronal activity supports the axon development of callosal projection neurons during different post-natal periods in the cerebral cortex. .  European Journal of Neuroscience31 ( 3 ) 410 - 424   2010.2Pre-synaptic and post-synaptic neuronal activity supports the axon development of callosal projection neurons during different post-natal periods in the cerebral cortex.Reviewed

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/j.1460-9568.2009.07070.x

    PubMed

  • Ageta-Ishihara N, Takemoto-Kimura S, Nonaka M, Adachi-Morishima A, Suzuki K, Kamijo S, Fujii H, Mano T, Blaeser F, Chatila TA, Mizuno H, Hirano T, Tagawa Y, Okuno H, Bito H. .  Control of cortical axon elongation by a GABA-driven Ca2+/calmodulin-dependent protein kinase cascade. .  The Journal of Neuroscience29 ( 43 ) 13720 - 13729   2009.10Control of cortical axon elongation by a GABA-driven Ca2+/calmodulin-dependent protein kinase cascade.Reviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1523/JNEUROSCI.3018-09.2009

    PubMed

  • Mizuno H, Hirano T, Tagawa Y. .  Evidence for activity-dependent cortical wiring: Formation of interhemispheric connections in neonatal mouse visual cortex requires projection neuron activity. .  The Journal of Neuroscience27 ( 25 ) 6760 - 6770   2007.6Evidence for activity-dependent cortical wiring: Formation of interhemispheric connections in neonatal mouse visual cortex requires projection neuron activity.Reviewed

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1523/JNEUROSCI.1215-07.2007

    PubMed

  • Tagawa Y, Kanold PO, Majdan M, & Shatz CJ. .  Multiple periods of functional ocular dominance plasticity in mouse visual cortex. .  Nature Neuroscience8 ( 3 ) 380 - 388   2005.3Multiple periods of functional ocular dominance plasticity in mouse visual cortex.Reviewed

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1038/nn1410

    PubMed

  • Tagawa Y, Sawai H, Ueda Y, Tauchi M, Nakanishi S. .  Immunohistological studies of metabotropic glutamate receptor-subtype 6-deficient mice show no abnormality of retinal cell organization and ganglion cell maturation. .  The Journal of Neuroscience19 ( 7 ) 2568 - 2579   1999.7Immunohistological studies of metabotropic glutamate receptor-subtype 6-deficient mice show no abnormality of retinal cell organization and ganglion cell maturation.Reviewed

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    Language:English   Publishing type:Doctoral thesis  

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  • Tagawa Y, Sawai H, Ueda Y, Tauchi M, & Nakanishi S. .  Immunohistological studies of metabotropic glutamate receptor-subtype 6-deficient mice show no abnormality of retinal cell organization and ganglion cell maturation. .  The Journal of Neuroscience19 ( 7 ) 2568 - 2579   1999.4Immunohistological studies of metabotropic glutamate receptor-subtype 6-deficient mice show no abnormality of retinal cell organization and ganglion cell maturation.Reviewed

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    PubMed

  • Hashimoto T, Inazawa J, Okamoto N, Tagawa Y, Bessho Y, Honda Y, & Nakanishi S. .  The whole nucleotide sequence and chromosomal localization of the gene for human metabotropic glutamate receptor subtype 6. .  European Journal of Neuroscience9   1226 - 1235   1997.6The whole nucleotide sequence and chromosomal localization of the gene for human metabotropic glutamate receptor subtype 6.Reviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

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  • Masu M, Iwakabe H, Tagawa Y, Miyoshi T, Yamashita M, Fukuda Y, Sasaki H, Hiroi K, Nakamura Y, Shigemoto R, Takada M, Nakamura K, Nakao K, Katsuki M, & Nakanishi S. .  Specific deficit of the ON response in visual transmission by targeted disruption of the mGluR6 gene. .  Cell80 ( 5 ) 757 - 765   1995.3Specific deficit of the ON response in visual transmission by targeted disruption of the mGluR6 gene.Reviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

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  • Sasai Y, Kageyama R, Tagawa Y, Shigemoto R, & Nakanishi S. .  Two mammalian helix-loop-helix factors structurally related to Drosophila hairy and Enhancer of split. .  Genes & Development 6   2620 - 2634   1992.12Two mammalian helix-loop-helix factors structurally related to Drosophila hairy and Enhancer of split.Reviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

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Books

  • Principles of Neurobiology

    Li Qun Luo( Role: Joint translator ,  Wiring of the visual system)

    Garland Science  2017.8 

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    Total pages:736   Responsible for pages:p169-210   Language:Japanese Book type:Textbook, survey, introduction

MISC

  • In utero 遺伝子導入法について Invited

    田川 義晃

    LABIO21   89   8 - 10   2023.5

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    Authorship:Lead author, Last author, Corresponding author   Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)   Publisher:日本実験動物協会  

  • Construction of visual circuits by spontaneous neuronal activity

    Yoshiaki Tagawa

    70 ( 1 )   23 - 27   2019.2

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media)  

  • 【脳神経回路のダイナミクスから探る脳の発達・疾患・老化】自発神経活動と視覚系神経回路のスクラップ&ビルド

    田川 義晃

    生体の科学   70 ( 1 )   23 - 27   2019.2

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    Publisher:(公財)金原一郎記念医学医療振興財団  

  • Activity-dependent callosal axon projections in neonatal mouse cerebral cortex. Reviewed

    Tagawa Y & Hirano T.

    Neural Plasticity   2012 ( 797295 )   1 - 10   2012.10

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    Language:English   Publishing type:Article, review, commentary, editorial, etc. (bulletin of university, research institution)  

    DOI: 10.1155/2012/797295

    PubMed

  • Activity-dependent development of interhemispheric connections in the visual cortex. Reviewed

    Tagawa Y, Mizuno H, Hirano T.

    Reviews in the Neurosciences   19 ( 1 )   19 - 28   2008.2

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    Language:English   Publishing type:Article, review, commentary, editorial, etc. (bulletin of university, research institution)  

    PubMed

Presentations

  • Yoshiaki Tagawa   Activity-dependent callosal axon projections in the developing neocortex  

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    Event date: 2019.8

    Language:Japanese   Presentation type:Oral presentation (general)  

  • Yoshiaki Tagawa et al.,   Activity-dependent formation and restoration of callosal axon projections in developing neocortex   Invited International conference

    Principles of Neocortical Development and Evolution  東京都医学総合研究所

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    Event date: 2019.7

    Language:English   Presentation type:Poster presentation  

    Venue:東京都医学総合研究所  

  • Yoshiaki Tagawa, Yuta Tezuka, Kenta Hagihara, Kenichi Ohki, Tomoo Hirano   Activity-dependent formation and restoration of callosal axon projections in developing neocortex.   International conference

    FAOPS Congress in conjunction with the 96th Annual meeting of the Physiological Society of Japan. 

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    Event date: 2019.3

    Language:English   Presentation type:Poster presentation  

  • Yoshiaki Tagawa   Activity-dependent callosal axon projections in the developing neocortex.   Invited International conference

    National Institute of Genetics

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    Event date: 2018.12

    Language:English   Presentation type:Oral presentation (invited, special)  

    Venue:National Institute of Genetics  

  • Activity-dependent callosal axon projections in developing neocortex  

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    Event date: 2018.11

    Language:Japanese   Presentation type:Oral presentation (general)  

  • Yoshiaki Tagawa   Activity-dependent formation and restoration of callosal axon projections in developing neocortex   International conference

    Cold Spring Harbor Asia meeting  Cold Spring Harbor Asia

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    Event date: 2018.9

    Language:English   Presentation type:Poster presentation  

  • 田川義晃   自発神経活動による大脳神経回路の形成機構   Invited

    生理学研究所「情動研究会」  生理学研究所

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    Event date: 2018.9

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Venue:愛知県岡崎市  

  • 田川義晃   マウス大脳の マクロな領域間投射と局所回路をつなぐ構築ロジック  

    鹿児島神経科学研究会 

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    Event date: 2018.6

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:鹿児島県指宿市  

  • 田川義晃   神経活動による大脳神経回路の形成   Invited

    鹿児島神経科学研究会  鹿児島神経科学研究会

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    Event date: 2017.9

    Language:Japanese   Presentation type:Symposium, workshop panel (nominated)  

    Venue:鹿児島大学  

  • Activity-dependent formation and restoration of callosal axon projections in the developing mouse neocortex.   Invited

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    Event date: 2017.8

    Language:English   Presentation type:Oral presentation (general)  

  • Tagawa Y   New approaches to research and development for generation and regeneration of neural circuits   Invited International conference

    Neuroscience2017 

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    Event date: 2017.7

    Language:English   Presentation type:Symposium, workshop panel (public)  

    Venue:Makuhari Messe  

  • Tagawa Yoshiaki, Tezuka Yuta, Hagihara Kenta, Ohki Kenichi, Hirano Tomoo   発達期の新皮質における脳梁軸索投射の活動依存的形成と回復(Activity-dependent formation and restoration of callosal axon projections in developing neocortex)  

    The Journal of Physiological Sciences  2019.6  (一社)日本生理学会

  • 中川 直, 水野 秀信, 田川 義晃   脳梁投射軸索のダイナミクスに関するtime-lapseイメージング(Time-lapse imaging of callosal axon projection dynamics in vivo)  

    日本生理学雑誌  2021.2  (一社)日本生理学会

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Research Projects

  • 神経活動に依存したスクラップアンドビルドによる大脳長距離神経回路の形成

    2019.4 - 2021.3

    科学研究費補助金  新学術領域研究

  • 自発神経活動に依存した大脳長距離軸索投射の形成・再編・再生

    2017.4 - 2019.3

    科学研究費補助金  新学術領域研究

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    2016.7 - 2017.6

    民間企業  国内共同研究 

  • 同期・非同期の自発神経活動による大脳皮質神経回路の形成とその障害

    2016.4 - 2019.3

    科学研究費補助金  基盤研究(C)

  • 哺乳期マウスの神経活動操作・記録実験による生後初期神経活動の役割の解明

    2013.4 - 2015.3

    科学研究費補助金  新学術領域研究

  • 活動依存的メカニズムに基づく大脳皮質長距離軸索投射の再建

    2011.4 - 2014.3

    科学研究費補助金  基盤研究(C)

  • 皮質2/3層興奮性細胞の特徴的な形態・機能獲得における神経活動の役割

    2011.4 - 2013.3

    科学研究費補助金  新学術領域研究

  • 大脳皮質の機能的神経回路の構築原理の解明

    2010.10 - 2016.3

    文部科学省  特色ある大学教育支援プログラム 

    大木研一、田川義晃

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    Grant type:Competitive

  • 大脳皮質の層特異的回路網構築における神経活動の役割

    2009.4 - 2011.3

    科学研究費補助金  若手研究(B)

  • Cross-modal可塑性における代謝型グルタミン酸受容体の役割の解明

    2006.4 - 2009.3

    科学研究費補助金  若手研究(B)

  • 神経ネットワークにおけるグルタミン酸受容体結合蛋白質の役割の解明

    2000.4 - 2001.3

    科学研究費補助金  基盤研究(C)

    田川義晃、金子鋭

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