Updated on 2021/03/23

写真a

 
SAHARA Hisashi
 
Organization
Research Field in Integrated Studies, Integrated Arts and Sciences Area Center for Advanced Biomedical Science and Swine Research, Institute for Research Promotion Organ Replacement and Xenotransplantation Surgery Associate Professor
Title
Associate Professor

Degree

  • 博士(医学) ( 2011.1   京都大学 )

Research Interests

  • 虚血再灌流傷害

  • 異種移植

  • 肺移植

  • ミニブタ

Research History

  • Kagoshima University   Associate Professor

    2012.4

Professional Memberships

  • 日本臓器保存生物医学会

    2010.5

  • 国際移植学会

    2008.6

  • 国際異種移植学会

    2008.6

  • アメリカ移植学会

    2006.10

  • 国際心肺移植学会

    2005.2

  • 日本外科学会

    1995.2

  • 日本呼吸器外科学会

    1995.2

  • 日本胸部外科学会

    1995.2

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Papers

  • Murokawa T, Sahara H, Sekijima M, Pomposelli T, Iwanaga T, Ichinari Y, Shimizu A, Yamada K. .  The protective effects of carbon monoxide against hepatic warm ischemia-reperfusion injury in MHC-inbred miniature swine. .  #IJ Gastrointest Surg#IR24 ( 5 ) 974 - 982   2020.5The protective effects of carbon monoxide against hepatic warm ischemia-reperfusion injury in MHC-inbred miniature swine.Reviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s11605-019-04283-0

  • Watanabe H, Ariyoshi Y, Pomposelli T, Takeuchi K, Ekanayake-Alper DK, Boyd LK, Arn SJ, Hawley RJ, Sahara H, Shimizu A, Ayares D, Lorber MI, Sykes M, Sachs DH, Yamada K. .  Intra-bone bone marrow transplantation from hCD47 transgenic pigs to baboons prolongs chimerism to >60 days and promotes increased porcine lung transplant survival. .  #IXenotransplantation#IR27 ( 1 ) e12552   2020.1Intra-bone bone marrow transplantation from hCD47 transgenic pigs to baboons prolongs chimerism to >60 days and promotes increased porcine lung transplant survival. Reviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/xen.12552

  • Sekijima M, Sahara H, Shimizu A, Iwanaga T, Murokawa T, Ariyoshi Y, Pomposelli T, Khosravi Maharlooei M, Sykes M, Yamada K. .  Preparation of hybrid porcine thymus containing non-human primate thymic epithelial cells in miniature swine. .  #IXenotransplantation#IR26 ( 6 ) e12543   2019.11Preparation of hybrid porcine thymus containing non-human primate thymic epithelial cells in miniature swine.Reviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/xen.12543

  • Wakamatsu M, Yamanouchi H, Sahara H, Iwanaga T, Kuroda R, Yamamoto A, Minami Y, Sekijima M, Yamada K, Kajiya K. .  Catechin and caffeine contents in green tea at different harvest periods and their metabolism in miniature swine. .  #IFood Science & Nutrition#IR7 ( 8 ) 2769 - 2778   2019.7Catechin and caffeine contents in green tea at different harvest periods and their metabolism in miniature swine. Reviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/fsn3.1143

  • Watanabe H, Sahara H, Nomura S, Tanabe T, Ekanayake-Alper DK, Boyd LK, Louras NJ, Asfour A, Danton MA, Ho SH, Arn SJ, Hawley RJ, Shimizu A, Nagayasu T, Ayares D, Lorber MI, Sykes M, Sachs DH, Yamada K. .  GalT-KO pig lungs are highly susceptible to acute vascular rejection in baboons, which may be mitigated by transgenic expression of hCD47 on porcine blood vessels. .  #IXenotransplantation#IR25 ( 5 ) e12391   2018.9GalT-KO pig lungs are highly susceptible to acute vascular rejection in baboons, which may be mitigated by transgenic expression of hCD47 on porcine blood vessels. Reviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/xen.12391

  • Sahara H, Sekijima M, Ariyoshi Y, Kawai A, Miura K, Waki S, Nathan L, Tomita Y, Iwanaga T, Nakano K, Matsunari H, Date H, Nagashima H, Shimizu A, Yamada K. .  Effects of carbon monoxide on early dysfunction and microangiopathy following GalT-KO porcine pulmonary xenotransplantation in cynomolgus monkeys .  #IXenotransplantation#IR25 ( 1 )   2018.1Effects of carbon monoxide on early dysfunction and microangiopathy following GalT-KO porcine pulmonary xenotransplantation in cynomolgus monkeysReviewed

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  • Sahara H, Watanabe H, Pomposelli T, Yamada K. .  Lung xenotransplantation .  #ICurr Opin Organ Transplant#IR22 ( 6 ) 541 - 548   2017.12Lung xenotransplantationReviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1097/MOT.0000000000000465

  • Sekijima M, Sahara H, Miki K, Villani V, Ariyoshi Y, Iwanaga T, Tomita Y, Yamada K. .  Hydrogen sulfide prevents renal ischemia-reperfusion injury in CLAWN miniature swine. .  #IJ Surg Res#IR219   165 - 172   2017.11Hydrogen sulfide prevents renal ischemia-reperfusion injury in CLAWN miniature swine.Reviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 110.1016/j.jss.2017.05.123.

  • Tanabe T, Watanabe H, Shah JA, Sahara H, Shimizu A, Nomura S, Asfour A, Danton M, Boyd L, Dardenne Meyers A, Ekanayake-Alper DK, Sachs DH, Yamada K. .  Role of intrinsic (graft) versus extrinsic (host) factors in the growth of transplanted organs following allogeneic and xenogeneic transplantation. .  #IAmerican Journal of Transplantation#IR17 ( 7 ) 1778 - 1790   2017.7Role of intrinsic (graft) versus extrinsic (host) factors in the growth of transplanted organs following allogeneic and xenogeneic transplantation. Reviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/ajt.14210

  • Miura K, Sahara H, Waki S, Kawai A, Sekijima M, Kobayashi T, Zhang Z, Wakai T, Shimizu A, Yamada K. .  Development of the intestinal transplantation model with major histocompatibility complex inbred CLAWN miniature swine. .  #ITransplantation Proceedings#IR48 ( 4 ) 1315 - 1319   2016.5Development of the intestinal transplantation model with major histocompatibility complex inbred CLAWN miniature swine. Reviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.transproceed.2016.01.023.

  • Miura K, Sahara H, Sekijima M, Kawai A, Waki S, Nishimura H, Setoyama K, Clayman ES, Shimizu A, Yamada K. .  Protective effect of neutralization of the extracellular high-mobility group box-1 on renal ischemia-reperfusion injury in miniature swine. .  #ITransplantation#IR98 ( 9 ) 937 - 943   2014.11Protective effect of neutralization of the extracellular high-mobility group box-1 on renal ischemia-reperfusion injury in miniature swine.Reviewed

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  • Sekijima, M. Waki, S. Sahara, H. Tasaki, M. Wilkinson, R. A. Villani, V. Shimatsu, Y. Nakano, K. Matsunari, H. Nagashima, H. Fishman, J. A. Shimizu, A. Yamada, K .  Results of life-supporting GalT-KO kidneys in cynomolgus monkeys using two different sources of GalT-KO swine. .  #ITransplantation#IR98 ( 4 ) 419 - 426   2014.8Results of life-supporting GalT-KO kidneys in cynomolgus monkeys using two different sources of GalT-KO swine. Reviewed

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  • Shimatsu Y, Yamada K, Horii W, Hirakata A, Sakamoto Y, Waki S, Sano J, Saitoh T, Sahara H, Shimizu A, Yazawa H, Sachs DH, Nunoya T .  Production of cloned NIBS (Nippon Institute for Biological Science) and α-1, 3-galactosyltransferase knockout MGH miniature pigs by somatic cell nuclear transfer using the NIBS breed as surrogates .  #IXenotransplantation#IR20 ( 3 ) 157 - 164   2013.1Production of cloned NIBS (Nippon Institute for Biological Science) and α-1, 3-galactosyltransferase knockout MGH miniature pigs by somatic cell nuclear transfer using the NIBS breed as surrogatesReviewed

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

  • 佐原寿史、脇 詩織、関島光裕、三浦宏平、河合昭浩、清水 章、山田和彦 .  常温体外肺循環回路(EVLP)下での一酸化炭素吸入によるミニブタ移植肺への効果. .  #I今日の移植#IR25 ( 6 ) 495 - 499   2012.12常温体外肺循環回路(EVLP)下での一酸化炭素吸入によるミニブタ移植肺への効果.

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  • Oku M, Okumi M, Shimizu A, Sahara H, Setoyama K, Nishimura H, Sada M, Scalea J, Ido A, Tsubouchi H, Yamada K .  Hepatocyte growth factor sustains Tregs and prolongs the survival of kidney allografts in MHC-inbred CLAWN-miniature swine. .  #ITransplantation#IR93 ( 2 ) 148 - 155   2012.1Hepatocyte growth factor sustains Tregs and prolongs the survival of kidney allografts in MHC-inbred CLAWN-miniature swine. Reviewed

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  • Veillette GR, Sahara H, Meltzer AJ, Weiss MJ, Iwamoto Y, Kim KM, Rosengard BR, Allan JS, Houser SL, Sachs DH, Benichou G, Madsen JC .  Autoimmune sensitization to cardiac myosin leads to acute rejection of cardiac allografts in miniature swine. .  #ITransplantation#IR91 ( 11 ) 1187 - 1191   2011.6Autoimmune sensitization to cardiac myosin leads to acute rejection of cardiac allografts in miniature swine. Reviewed

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  • Sahara H, Shimizu A, Setoyama K, Oku M, Okumi M, Nishimura H, Oriyanhan W, Tasaki M, Scalea J, Wada H, Bando T, Date H, Yamada K .  Beneficial effects of perioperative low-dose inhalation of carbon monoxide on pulmonary allograft survival in MHC-inbred CLAWN miniature swine .  #ITransplantation#IR90 ( 12 ) 1336 - 1343   2010.12Beneficial effects of perioperative low-dose inhalation of carbon monoxide on pulmonary allograft survival in MHC-inbred CLAWN miniature swineReviewed

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  • Sahara H, Shimizu A, Setoyama K, Okumi M, Oku M, Samelson-Jones E, Yamada K .  Carbon monoxide reduces pulmonary ischemia-reperfusion injury in miniature swine. .  #IJ Thorac Cardiovasc Surg#IR139 ( 6 ) 1594 - 1601   2010.6Carbon monoxide reduces pulmonary ischemia-reperfusion injury in miniature swine.Reviewed

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  • Sakai H, Nakano Y, Muro S, Hirai T, Takubo Y, Oku Y, Hamakawa H, Takahashi A, Sato T, Chen F, Sahara H, Fujinaga T, Sato K, Sonobe M, Shoji T, Miyahara R,Okubo K, Bando T, Hirata T, Date H, Mishima M .  Age-related changes in the trachea in healthy adults .  #IAdv Exp Med Biol#IR662   115 - 120   2010Age-related changes in the trachea in healthy adultsReviewed

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  • Weiss MJ, Guenther DA, Mezrich JD, Sahara H, Ng CY, Meltzer AJ, Sayre JK, Cochrane ME, Pujara AC, Houser SL, Sachs DH, Rosengard BR, Allan JS, Benichou G, Madsen JC .  The indirect alloresponse impairs the induction but not maintenance of tolerance to MHC class I-disparate allografts .  #IAm J Transplant#IR9 ( 1 ) 105 - 113   2009.1The indirect alloresponse impairs the induction but not maintenance of tolerance to MHC class I-disparate allograftsReviewed

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MISC

  • 腎移植の現況と残された課題. 異種移植のヒトへの応用.

    関島光裕, 佐原寿史, 山田和彦

    #I腎と透析#IR   87 ( 1 )   128 - 131   2019.1

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

  • 夢ではなくなった異種臓器移植と免疫寛容誘導戦略の重要性 :独自の免疫寛容誘導療法による異種移植の臨床応用への試み

    山田和彦, 佐原寿史, 関島光裕

    #IOrgan Biology#IR   25 ( 2 )   169 - 175   2018.6

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

  • 【糖尿病と腎疾患2015】糖尿病性腎症の病理と基礎研究の最前線. 新たな膵臓、膵ラ氏島移植による糖尿病性腎症の制御

    山田和彦, 佐原寿史, 関島光裕

    #I腎と透析#IR   78 ( 6 )   131 - 137   2015.6

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

  • 【毒ガス?いいえ治療薬です】新たな治療薬としての一酸化炭素への期待.

    佐原寿史, 関島光裕, 山田和彦

    #I臨床麻酔#IR   39 ( 6 )   855 - 864   2015.6

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  • 異種移植は前臨床大動物実験成果としてすでに数ヵ月から年単位の臓器生着に至っている

    佐原寿史, 松本慎一, 山田和彦

    #IOrgan Biology#IR   22 ( 1 )   23 - 30   2015.1

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  • 【移植医療の未来像-次の半世紀へ向けて-】異種移植の未来動向

    佐原寿史, 関島光裕, 山田和彦

    #I移植#IR   50 ( 1 )   323 - 330   2015.1

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  • 【腎移植にかかわる医療従事者の役割と最新の知識】 異種間移植の展望

    山田和彦, 佐原寿史, 関島光裕

    #I腎と透析#IR   78 ( 1 )   139 - 146   2015.1

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

  • 【移植・再生医学最前線】移植医療の現状と展望. 異種移植. 臨床応用をめざした前臨床研究の進歩

    佐原寿史, 山田和彦

    #I消化器外科#IR   37 ( 8 )   1279 - 1285   2014.8

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

  • 【移植医療の新たな展開】異種移植はどこまできたか

    佐原寿史, 山田和彦

    #IMedical Science Digest#IR   40 ( 12 )   582 - 585   2014.6

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  • 大動物を用いた前臨床虚血再灌流障害モデルの作製とマージナルドナー活用戦略

    山田和彦, 佐原寿史

    #IOrgan Biology#IR   20 ( 2 )   122 - 130   2014.1

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  • ドナーに対する一酸化炭素吸入療法による移植肺生着延長効果-前臨床ミニブタモデルを用いた新たな臓器保存方法への発展

    佐原寿史, 山田和彦

    #IOrgan Biology#IR   19 ( 1 )   25 - 28   2012.1

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  • 【臓器移植の新時代】 研究の新しい展開 異種臓器移植の臨床応用をめざして: 前臨床異種移植はここまで進んでいる

    山田和彦, 佐原寿史

    #I医学のあゆみ#IR   237 ( 5 )   559 - 566   2011.5

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Presentations

  • 佐原寿史.   ワークショップ 呼吸器1「肺移植における抗HLA抗体と抗体関連拒絶反応」「抗体関連拒絶反応を理解するための大動物モデル確立の重要性」  

    第73回日本胸部外科学会定期学術集会.  

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    Event date: 2020.10

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:名古屋市  

  • Sahara H, Sekijima M, Iwanaga T, Ichinari Y, Shimizu A.   Upregulation of intragraft inflammatory cytokine is associated with pulmonary allograft rejection in MHC-inbred CLAWN miniature swine.   International conference

    International Society for Heart and Lung Transplantation 40th Annual Meeting 

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    Event date: 2020.4

    Language:English   Presentation type:Poster presentation  

    Venue:Montreal  

  • 佐原寿史.   シンポジウム「前臨床異種肺移植研究の現状と課題」   Invited

    第22回日本異種移植研究会.  

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    Event date: 2020.2

    Language:Japanese   Presentation type:Symposium, workshop panel (nominated)  

    Venue:仙台市  

  • 佐原寿史, 関島光裕, 岩永健裕, 市成ゆりか, 清水 章, 山田和彦.   MHC 確立ミニブタを用いた慢性移植実験系の意義.  

    第72回日本胸部外科学会定期学術集会.  

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    Event date: 2019.10 - 2019.11

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:京都市  

  • 関島光裕, 佐原寿史, 岩永健裕, 市成ゆりか, 山田和彦.   慢性評価を可能とするブタ同所性肝移植モデル-MHC確立CLAWN系ミニブタを用いた前臨床研究-.  

    第7回日本先進医工学ブタ研究会.  

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    Event date: 2019.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:今治市  

  • 関島光裕, 佐原寿史, 有吉勇一, 室川剛廣, 岩永健裕, 市成ゆりか, 清水 章, 山田和彦.   MHC確立CLAWNミニブタを用いた長期生存ブタ同所性肝移植モデルの確立.  

    第55回日本移植学会総会.  

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    Event date: 2019.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:広島市  

  • 関島光裕, 佐原寿史, 近藤晃, 佐多荘司郎, 持田康子, 永野武志, 尊田和徳, 白石幸三, 山田和彦.   短期留置型および永久留置型カテーテル透析における脱血不全と再循環率の検討..  

    第23回日本アクセス研究会学術集会・総会.  

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    Event date: 2019.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:横浜市  

  • Ariyoshi Y, Takeuchi K, Pomposelli T, Ekanayake-Alper D, Schuetz C, Sahara H, Arn S, Boyd L, Estime E, Arn S, Ayares D, Lorber M, Sykes M, Sachs D, Yamada K.   Newly-revealed antibody targets lead to the early loss of triple knockout pig kidneys in a pig to baboon model.   International conference

    American Transplant Congress 2019 

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    Event date: 2019.6

    Language:English   Presentation type:Oral presentation (general)  

    Venue:Boston  

  • Sahara H, Ariyoshi Y, Sekijima M, Iwanaga T, Shimizu A, Yamada K.   Effects of static subnormothermic preservation of extended warm ischemic porcine kidneys assessed by ex-vivo Machine perfusion and renal transplant model.   International conference

    American Transplant Congress 2019 

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    Event date: 2019.6

    Language:English   Presentation type:Oral presentation (general)  

    Venue:Boston  

  • 山田和彦, 佐原寿史, 関島光裕, 渡邉洋之助, 有吉勇一, 竹内和博   シンポジウム「What additional genes should be altered and what immunologic strategy should be included for successful clinical xeno transplantation」  

    第21回日本異種移植研究会 

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    Event date: 2019.2

    Language:Japanese   Presentation type:Symposium, workshop panel (nominated)  

    Venue:沖縄県  

  • 関島光裕, 佐原寿史, 室川剛廣, 有吉勇一, 岩永健裕, 市成ゆりか, 山田和彦.   ブタ・霊長類間異種免疫寛容を目指したハイブリッド胸腺の確立とその有用性.  

    第21回日本異種移植研究会.  

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    Event date: 2019.2

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:那覇市  

  • 佐原寿史   スポンサードセミナー1「異種肺移植成績向上を目指した挑戦 ~日米における前臨床異種移植実験から見えてきた課題」  

    第35回日本肺および心肺移植研究会 

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    Event date: 2019.1

    Language:Japanese   Presentation type:Symposium, workshop panel (nominated)  

    Venue:長崎県  

  • 関島光裕, 佐原寿史, 山田和彦, 尊田和徳, 白石幸三.   当施設におけるヘパリン共有結合型e-PTFE人工血管と従来型e-PTFE人工血管との開存率の比較・検討.  

    第21回日本アクセス研究会学術集会・総会 

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    Event date: 2018.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:三島市  

  • 佐原寿史, 関島光裕, 室川剛廣, 岩永健裕, 市成ゆりか, 山田和彦   シンポジウ2「医療用ブタの産業化にまつわる課題」「固形臓器の異種移植の展望」.  

    第6回日本先進医工学ブタ研究会 

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    Event date: 2018.10

    Language:Japanese   Presentation type:Symposium, workshop panel (nominated)  

    Venue:静岡県  

  • 関島光裕, 佐原寿史, 小川勇一, 三木克幸, 室川剛廣, 三浦宏平, 岩永健裕, 市成ゆりか, 渕之上昌平, 清水 章, 山田和彦.   肝・小腸移植による新たな免疫寛容誘導戦略の確立-MHC確立クラウン系ミニブタを用いた評価.  

    第6回日本先進医工学ブタ研究会.  

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    Event date: 2018.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:三島市  

  • 関島光裕, 佐原寿史, 小川勇一, 三木克幸, 室川剛廣, 三浦宏平, 岩永健裕, 市成ゆりか, 渕之上昌平, 清水 章, 山田和彦   MHC確立クラウン系ミニブタを用いた肝・小腸移植モデルにおける免疫寛容誘導の確立.  

    第54回日本移植学会総会.  

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    Event date: 2018.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:東京  

  • 関島光裕, 佐原寿史, 有吉勇一, 室川剛廣, 岩永健裕, 市成ゆりか, 清水 章, 山田和彦.   ブタ・霊長類間異種免疫寛容を目指したハイブリッド胸腺の確立とその有用性.  

    第54回日本移植学会総会.  

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    Event date: 2018.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:東京  

  • Murokawa T, Sahara H, Sekijima M, Iwanaga T, Ariyoshi Y, Ichinari Y, Shimizu A, Yamada K.   Inhalation of carbon monoxide protects liver against warm ischemia-reperfusion injury in CLAWN miniature swine.   International conference

    TTS2018 (27th International Congress of The Transplantation Society) 

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    Event date: 2018.6 - 2018.7

    Language:English   Presentation type:Oral presentation (general)  

    Venue:Madrid  

  • Sekijima M, Ariyoshi Y, Sahara H, Kawai A, Iwanaga T, Murokawa T, Ichinari Y, Shimizu A, Kusaka M, Yamada K.   Effects of static subnormothermic preservation on extended warm ischemic porcine kidneys assessed by normothermic machine perfusion and renal transplantation.   International conference

    TTS2018 (27th International Congress of The Transplantation Society) 

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    Event date: 2018.6 - 2018.7

    Language:English   Presentation type:Oral presentation (general)  

    Venue:Madrid  

  • Sahara H, Sekijima M, Murokawa T, Iwanaga T, Ariyoshi Y, Ichinari Y, Shimizu A, Yamada K.   Induction of tolerance to fully allogeneic pulmonary allograft by adenosine A2A receptor agonist in MHC-defined CLAWN miniature swine.   International conference

    TTS2018 (27th International Congress of The Transplantation Society) 

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    Event date: 2018.6 - 2018.7

    Language:English   Presentation type:Oral presentation (general)  

    Venue:Madrid  

  • Watanabe H, Nomura S, Sahara H, Pomposelli T, Ariyoshi Y, Boyd KL, Ekanayake-Alper D, Tanabe T, Glor H, Arn S, Hawley RJ, Shimizu A, Ayares D, Lorber M, Sykes M, Sachs DH, Yamada K.   Transgenic expression of hCD47 on vessels in porcine GalTKO lung grafts in baboons may mitigate acute vascular rejection in baboons: Up to 13 days graft survival in baboons.   International conference

    TTS2018 (27th International Congress of The Transplantation Society) 

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    Event date: 2018.6 - 2018.7

    Language:English   Presentation type:Oral presentation (general)  

    Venue:Madrid  

  • Murokawa T, Sahara H, Sekijima M, Iwanaga T, Ariyoshi Y, Ichinari Y, Shimizu A, Yamada K.   Carbon monoxide can ameliorate hepatic warm ischemia-reperfusion injury in a preclinical miniature swine model.   International conference

    ILTS (International Liver Transplantation Society) 2018 Annual Congress 

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    Event date: 2018.5

    Language:English   Presentation type:Poster presentation  

    Venue:Lisbon  

  • 佐原寿史, 関島光裕, 室川剛廣, 岩永健裕, 市成ゆりか, 清水 章, 山田和彦.   MHC確立クラウン系ミニブタを用いた慢性肺移植実験基礎モデル.  

    第35回日本呼吸器外科学会定期学術集会.  

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    Event date: 2018.5

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:千葉市  

  • Sekijima M, Hachisuka K, Ide H, Morita S, Masaki N, Sata S, Sonda K, Shiraishi K, Sahara H, Yamada K.   Effect of heparin bonded e-polytetrafluoroethylene (e-PTFE) grafts (PROPARTENR) on the improvement of long-term patency rates in hemodialysis patients.   International conference

    Vascular Access for Hemodialysis Symposium2018 

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    Event date: 2018.5

    Language:English   Presentation type:Poster presentation  

    Venue: New Orleans  

  • 山田和彦, 佐原寿史.   独自免疫寛容誘導療法を用いたブタ・ヒヒ間異種腎・異種肺移植-6か月以上の正常ブタ腎機能とブタ特異的免疫無反応ならびに世界最長のブタ肺生着.  

    第20回日本異種移植研究会 

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    Event date: 2018.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:大阪市  

  • 関島光裕, 井出大志, 佐多荘司郎, 佐原寿史, 山田和彦, 尊田和徳, 白石幸三.   ACUSEALR を用いた静脈?静脈バイパス術における当院の取り組みとその成果.  

    第23回バスキュラーアクセスインターベンション治療(VAIVT)研究会 

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    Event date: 2018.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:東京  

  • Sahara H, Sekijima M, Iwanaga T, Murokawa T, Ariyoshi Y, Ichinari Y, Shimizu A, Yamada K.   The beneficial role of adenosine A2A receptor agonist on tolerance induction to fully allogeneic pulmonary allograft in large animal model.   International conference

    The 15th Congress of the Asian Society of Transplantation 

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    Event date: 2017.11

    Language:English   Presentation type:Poster presentation  

    Venue:Cebu, Philippines  

  • Sekijima M, Kawai A, Ariyoshi Y, Sahara H, Iwanaga T, Murokawa T, Ichinari Y, Shimizu A, Kusaka M, Yamada K   Beneficial effects of static subnormothermic preservation of extended warm ischemic kidneys assessed by ex-vivo machine perfusion and orthotopic renal transplant model in CLAWN miniature swine.   International conference

    The 15th Congress of the Asian Society of Transplantation 

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    Event date: 2017.11

    Language:English   Presentation type:Poster presentation  

    Venue:Cebu, Philippines  

  • Murokawa T, Sahara H, Sekijima M, Iwanaga T, Ariyoshi Y, Ichinari Y, Shimizu A, Yamada K   Effects of exogenous administration of carbon monoxide on ameliorating hepatic warm ischemia-reperfusion injury in CLAWN miniature swine.   International conference

    The 15th Congress of the Asian Society of Transplantation 

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    Event date: 2017.11

    Language:English   Presentation type:Poster presentation  

    Venue:Cebu, Philippines  

  • Iwanaga T, Sahara H, Sekijima M, Murokawa T, Ariyoshi Y, Ichinari Y, Shimizu A, Yamada K   MHC-defined CLAWN miniature as a valuable model for preclinical translational research in transplantation.   International conference

    The 15th Congress of the Asian Society of Transplantation 

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    Event date: 2017.11

    Language:English   Presentation type:Oral presentation (general)  

    Venue:Cebu, Philippines  

  • 山田和彦, 佐原寿史, 関島光裕   シンポジウム7「異種移植」「夢ではなくなった異種臓器移植と免疫寛容誘導戦略の重要性」  

    第44回日本臓器保存生物医学会学術集会 

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    Event date: 2017.11

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:大阪市  

  • 佐原寿史, 関島光裕, 室川剛廣, 岩永健裕, 市成ゆりか, 清水章, 山田和彦.   MHC確立クラウン系ミニブタを用いた慢性肺移植実験基礎モデル.  

    第35回日本呼吸器外科学会定期学術集会. 

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    Event date: 2017.11

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:千葉市  

  • 佐原寿史, 関島光裕, 山田和彦   シンポジウム7「異種移植」「世界最長の GalT-KO ブタ・霊長類間異種移植肺生着への道のりと今後の課題」  

    第44回日本臓器保存生物医学会学術集会 

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    Event date: 2017.11

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:大阪市  

  • Sahara H.   招待講演Session 2: Regenerative biomedical research using Minipig: Translational transplantation research using MHC-defined CLAWN miniature swine.   Invited International conference

    2017 KIT Minipig International Forum 

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    Event date: 2017.10

    Language:Japanese   Presentation type:Symposium, workshop panel (nominated)  

    Venue:Korea  

  • 佐原寿史, 関島光裕, 室川剛廣, 有吉勇一, 岩永健裕, 市成ゆりか, 清水 章, 山田和彦   シンポジウム3「創薬・医療機器開発におけるブタの利用」「クラウン系ミニブタを用いた産学共同医療機器開発前臨床研究から実用化への展望」.  

    第5回日本先進医工学ブタ研究会 

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    Event date: 2017.10

    Language:Japanese   Presentation type:Symposium, workshop panel (nominated)  

    Venue:静岡県  

  • 山田和彦, 佐原寿史, 関島光裕, 室川剛廣, 有吉勇一, 岩永健裕, 市成ゆりか, 清水 章.   シンポジウム1「異種移植・再生医療研究領域での研究開発と課題」「先進医工学ブタを用いた異種移植・再生医療研究の進展」.  

    第5回日本先進医工学ブタ研究会 

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    Event date: 2017.10

    Language:Japanese   Presentation type:Symposium, workshop panel (nominated)  

    Venue:静岡県  

  • 関島光裕, 棈松昌彦, 佐原寿史, 岩永健裕, 脇 詩織, 室川剛廣, 三浦直樹, 市成ゆりか, 小宮節郎, 山田和彦.   クラウン系ミニブタ脊髄損傷モデル.  

    第5回日本先進医工学ブタ研究会 

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    Event date: 2017.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:三島市  

  • 室川剛廣, 佐原寿史, 関島光裕, 岩永健裕, 有吉勇一, 市成ゆりか, 清水 章, 山田和彦.   肝温虚血再灌流障害に対する一酸化炭素吸入の有効性~クラウン系ミニブタを用いた前臨床研究.  

    第5回日本先進医工学ブタ研究会 

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    Event date: 2017.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:三島市  

  • 佐原寿史, 渡邊洋之助, 土肥良一郎, 清水 章, 永安 武, 山田和彦   GalT-KOブタ・霊長類間異種肺移植の成績向上.  

    第70回日本胸部外科学会定期学術集会 

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    Event date: 2017.9

    Language:Japanese   Presentation type:Poster presentation  

    Venue:札幌市  

  • Watanabe H, Sahara H, Nomura S, Tanabe T, Doi R, Ekanayake-Alper D, Boyd L, Danton M, Arn J, Hawley J, Shimizu A, Lorber M, Sykes M, Sachs D, Yamada K.   Histologically proven survival of porcine lung xenografts in baboons for up to 10 days using double transgenic hCD47/hCD55 GalT-KO donors.   International conference

    14th Congress IXA (International Xenotransplantation Association 2017) 

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    Event date: 2017.9

    Language:English   Presentation type:Oral presentation (general)  

    Venue:Baltimore  

  • Yamada K, Tanabe T, Lanaspa M, Watanabe H, Rivard C, Sekijima M, Shah J, Tasaki M, Sahara H, Shimizu A, Sachs D, Johnson R.   The roles of CD80 upregulation and human CD47 expression on glomerular podocytes in development of proteinuria following pig-to baboon renal xenotransplantation.   International conference

    14th Congress IXA (International Xenotransplantation Association 2017) 

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    Event date: 2017.9

    Language:English   Presentation type:Oral presentation (general)  

    Venue:Baltimore  

  • 佐原寿史, 岩永健裕, 瀬戸山健太郎, 関島光裕, 室川剛廣, 有吉勇一, 市成ゆりか, 山田和彦   シンポジウム「実験動物としてのブタ-最新の応用例から動物福祉まで-」「MHC確立クラウン系ミニブタを用いた前臨床同種・異種移植研究の実際」  

    第160回日本獣医学会学術集会 

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    Event date: 2017.9

    Language:Japanese   Presentation type:Symposium, workshop panel (nominated)  

    Venue:鹿児島市  

  • 室川剛廣, 佐原寿史, 関島光裕, 岩永健裕, 有吉勇一, 市成ゆりか, 清水 章, 山田和彦   クラウン系ミニブタを用いた肝虚血再灌流障害(IRI)に対する一酸化炭素(CO)の有効性評価.  

    第53回日本移植学会総会 

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    Event date: 2017.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:旭川市  

  • 関島光裕, 有吉勇一, 佐原寿史, 岩永健裕, 室川剛廣, 市成ゆりか, 清水 章, 山田和彦   MHC確立クラウン系ミニブタを用いた慢性大動物移植実験による常温灌流保存法(NMP法: Normothermic Machine Perfusion)の有効性評価  

    第53回日本移植学会総会 

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    Event date: 2017.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:旭川市  

  • 山田和彦, 田邉 起, 佐原寿史, 関島光裕, 田﨑正行   臓器横断的シンポジウム7「移植後における免疫寛容の誘導」「独自の胸腺移植併用による異種腎移植と遺伝子改変による6か月以上のブタ・ヒヒ間正常異種腎機能と免疫学的抗体ドナー無反応の達成」  

    第53回日本移植学会総会 

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    Event date: 2017.9

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:旭川市  

  • 佐原寿史, 岩永健裕, 関島光裕, 有吉勇一, 室川剛廣, 市成ゆりか, 清水 章, 山田和彦   臓器横断的シンポジウム7「移植後における免疫寛容の誘導」「MHC確立クラウン系ミニブタ脳死肺移植モデルを用いた新たな免疫寛容誘導戦略」  

    第53回日本移植学会総会 

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    Event date: 2017.9

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:旭川市  

  • 佐原寿史, 関島光裕, 室川剛廣, 岩永健裕, 市成ゆりか, 山田和彦   MHC確立クラウンミニブタを用いたアデノシンA2A受容体アゴニスト(CGS21680)投与による移植肺免疫寛容誘導.  

    第34回日本呼吸器外科学会総会 

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    Event date: 2017.5

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:福岡市  

  • Ariyoshi Y, Sekijima M, Sahara H, Murokawa T, Shimizu A, Yamada K   Beneficial effects of hydrogen sulfide (H2S) on renal ischemia-reperfusion Injury (IRI) in CLAWN miniature swine.   International conference

    AUA2017 

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    Event date: 2017.5

    Language:English   Presentation type:Poster presentation  

    Venue:Boston  

  • Sahara H, Sekijima M, Murokawa T, Ariyoshi Y, Iwanaga T, Ichinari Y, Shimizu A, Yamada K   Successful induction of tolerance of fully allogeneic lung graft with adenosine A2A receptor (A2AR) agonist in MHC-defined CLAWN miniature swine.   International conference

    American Transplant Congress 2017 

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    Event date: 2017.4 - 2017.5

    Language:English   Presentation type:Oral presentation (general)  

    Venue:Chicago  

  • Ariyoshi Y, Sekijima M, Sahara H, Murokawa T, Shimizu A, Yamada K   Beneficial effects of hydrogen sulfide (H2S) on renal ischemia-reperfusion Injury (IRI) in CLAWN miniature swine.   International conference

    American Transplant Congress 2017 

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    Event date: 2017.4 - 2017.5

    Language:English   Presentation type:Poster presentation  

    Venue:Chicago  

  • Sahara H, Sekijima M, Murokawa T, Ariyoshi Y, Iwanaga T, Ichinari Y, Shimizu A, Yamada K   Effect of perioperative treatment with adenosine A2A receptor agonist on pulmonary allograft survival in MHC-inbred CLAWN miniature swine.   International conference

    International Society for Heart and Lung Transplantation 37th Annual Meeting 

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    Event date: 2017.4

    Language:English   Presentation type:Oral presentation (general)  

    Venue:San Diego  

  • 佐原寿史, 関島光裕, 室川剛廣, 有吉勇一, 岩永健裕, 市成ゆりか, 齋藤敏樹, 中野和明, 松成ひとみ, 長嶋比呂志, 山田和彦   シンポジウム1「先端医療技術の開発」「臨床実施を目指したミニブタ・霊長類間前臨床異種移植研究の推進.  

    第4回日本先進医工学ブタ研究会 

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    Event date: 2016.10

    Language:Japanese   Presentation type:Symposium, workshop panel (nominated)  

    Venue:東京都  

  • 有吉勇一、佐原寿史、関島光裕、室川剛廣、岩永健裕、市成ゆりか、山田和彦   温虚血腎に対する移植前常温持続灌流の有用性-MHC確立クラウン系ミニブタを用いた慢性腎移植.  

    第4回日本先進医工学ブタ研究会 

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    Event date: 2016.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:静岡県  

  • 室川剛廣、佐原寿史、関島光裕、有吉勇一、岩永健裕、市成ゆりか、清水章、山田和彦   MHC確立クラウン系ミニブタを用いた肝移植モデルの確立.  

    第4回日本先進医工学ブタ研究会 

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    Event date: 2016.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:静岡県  

  • 佐原寿史、関島光裕、室川剛廣、有吉勇一、岩永健裕、市成ゆりか、清水 章、山田和彦   MHC確立クラウン系ミニブタを用いた前臨床肺移植実験モデル展開  

    第69回日本胸部外科学会定期学術集会 

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    Event date: 2016.9 - 2016.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:岡山市  

  • Ariyoshi Y, Sahara H, Sekijima M, Murokawa T, Iwanaga T, Ichinari Y, Shimizu A, Yamada K   Effects of brain death (BD) or cardiac death (DCD) on allogeneic lung graft survival in preclinical MHC-inbred CLAWN miniature swine.   International conference

    26th International Congress of the Transplantation Society 

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    Event date: 2016.8

    Language:English   Presentation type:Oral presentation (general)  

    Venue:Hong Kong  

    国際学会

  • Sekijima M, Sahara H, Morita S, Ogawa Y, Miki K, Murokawa T, Iwanaga T, Ichinari Y, Shimizu A, Yamada K   Hydrogen sulfide prevents the kidney from ischemia ?reperfusion injury in CLAWN miniature swine.   International conference

    26th International Congress of the Transplantation Society 

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    Event date: 2016.8

    Language:English   Presentation type:Poster presentation  

    Venue:Hong Kong  

    国際学会

  • Sahara H, Nagashima H, Sekijima M, Murokawa T, Iwanaga T, Ariyoshi Y, Ichinari Y, Nakano K, Matsunari H, Shimizu A, Yamada K   Carbon monoxide reduces acute pulmonary dysfunction in GalT-KO pig-to-cynomolgus monkey orthotopic lung transplantation.   International conference

    26th International Congress of the Transplantation Society 

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    Event date: 2016.8

    Language:English   Presentation type:Oral presentation (general)  

    Venue:Hong Kong  

    国際学会

  • Murokawa T, Sahara H, Iwanaga T, Sekijima M, Ariyoshi Y, Ichinari Y, Shimizu A, Yamada K   DNA-typed, MHC-inbred CLAWN miniature swine represent a highly-valuable species for the development of preclinical translational research in transplantation and regenerative medicine.   International conference

    26th International Congress of the Transplantation Society 

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    Event date: 2016.8

    Language:English   Presentation type:Oral presentation (general)  

    Venue:Hong Kong  

    国際学会

  • Waki S, Sahara H, Mitsui K, Sekijima M, Murokawa T, Iwanaga T, Ichinari Y, Kosai K, Yamada K   Efficacious combination of substrate and medium for feeder-free culture of naive porcine iPS.   International conference

    26th International Congress of the Transplantation Society 

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    Event date: 2016.8

    Language:English   Presentation type:Poster presentation  

    Venue:Hong Kong  

    国際学会

  • 佐原寿史、関島光裕、室川剛廣、岩永健裕、市成ゆりか、山田和彦   前臨床異種肺移植実験の課題と展開  

    第33回日本呼吸器外科学会総会 

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    Event date: 2016.5

    Language:Japanese   Presentation type:Poster presentation  

    Venue:京都  

  • Sahara H, Sekijima M, Iwanaga T, Ichinari Y, Shimizu A, Yamada K   MHC-inbred CLAWN miniature swine as preclinical large animal model for lung transplantation.   International conference

    International Society for Heart and Lung Transplantation 36th Annual Meeting 

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    Event date: 2016.4

    Language:English   Presentation type:Oral presentation (general)  

    Venue:Washington DC  

  • 佐原寿史、関島光裕、三浦宏平、河合昭浩、田﨑正行、岩永健裕、清水 章、山田和彦   前臨床異種移植実験の進歩と今後の展開  

    第116回日本外科学会定期学術集会 

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    Event date: 2016.4

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:大阪  

  • 関島光裕、佐原寿史、山田和彦   シンポジウム10. Translational Research. 「硫化水素による新規腎臓保護戦略:臨床応用に向けた大動物実験」  

    第49回日本臨床腎移植学会 

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    Event date: 2016.3

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:米子市  

  • 佐原寿史, 渡邊洋之助, 田邉起, 野村俊一郎, 清水章, 山田和彦   GalT-KOブタ・ヒヒ間異種肺移植―早期異種移植肺廃絶の回避とその生着.  

    第19回日本異種移植研究会 

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    Event date: 2016.2

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:京都市  

  • 佐原寿史、関島光裕、三浦宏平、河合昭浩、田﨑正行、岩永健裕、清水 章、山田和彦   前臨床異種移植実験の進歩と今後の展開  

    第18回日本異種移植研究会 

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    Event date: 2016.2

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:長崎市  

  • 関島光裕、佐原寿史、室川剛廣、岩永健裕、市成ゆりか、山田和彦   ブタ-ヒヒ異種腎移植モデルにおけるporcine-CMV感染の早期拒絶反応に対する影響  

    第18回日本異種移植研究会 

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    Event date: 2016.2

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:長崎市  

  • 田邉 起、室川剛廣、関島光裕、渡邉洋之助、佐原寿史、山田和彦   ブタ・霊長類間異種腎移植:蛋白尿とCD80 up-regulation  

    第18回日本異種移植研究会 

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    Event date: 2016.2

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:長崎市  

  • Sahara H, Waki S, Mitsui K, Sekijima M, Iwanaga T, Ichinari Y, Kosai K, Yamada K   Establishment of feeder free culture of naive state of porcine iPS cells   International conference

    IPITA - IXA - CTS 2015 Joint Congress 

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    Event date: 2015.11

    Language:English   Presentation type:Oral presentation (general)  

    Venue:Melbourne  

  • Sahara H, Nagashima H, Sekijima M, Ichinari Y, Iwanaga T, Nakano K, Matsunari H, Date H, Shimizu A, Yamada K   Effects and mechanisms of carbon monoxide on reducing hyperacute dysfunction and microangiopathy in GalT-KO pulmonary xenotransplantation   International conference

    IPITA - IXA - CTS 2015 Joint Congress 

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    Event date: 2015.11

    Language:English   Presentation type:Oral presentation (general)  

    Venue:Melbourne  

  • 関島光裕、佐原寿史、山田和彦   シンポジウム (3).前臨床ブタ・霊長類間移植成績向上戦略:遺伝子改変ブタ+新規免疫抑制療法+ドナーブタサイトメガロウィルス(pCMV)排除による 90 日間以上の異種移植腎生着  

    第42回日本臓器保存生物医学会学術集会 

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    Event date: 2015.11

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:盛岡市  

  • 小林 篤、大原絵里、三浦清豊、徳長 靖、山崎 彬、佐原寿史、山田和彦   シンポジウム3「畜産研究から実験用ブタへの橋渡しおよび応用研究」高圧下過冷却状態での革新的臓器保存法-前臨床クラウン系ミニブタモデルを用いた産学共同前臨床研究  

    第3回日本先進医工学ブタ研究会 

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    Event date: 2015.10

    Language:Japanese   Presentation type:Symposium, workshop panel (nominated)  

    Venue:東京都  

  • 佐原寿史、関島光裕、岩永健裕、市成ゆりか、山田和彦   シンポジウム5「実験用ブタを用いた各種応用研究」Medical Gasを用いた新たな移植医療:硫化水素の有用性  

    第3回日本先進医工学ブタ研究会 

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    Event date: 2015.10

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:東京都  

  • 関島光裕、佐原寿史、田﨑正行、岩永健裕、市成ゆりか、清水 章、山田和彦   シンポジウム4「遺伝子改変ブタの開発と研究応用」ミニブタ・霊長類間異種移植成績を向上させるためには  

    第3回日本先進医工学ブタ研究会 

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    Event date: 2015.10

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:東京都  

  • 佐原寿史、関島光裕、三浦宏平、河合昭浩、脇 詩織、岩永健裕、市成ゆりか、清水 章、山田和彦   臓器横断的ワークショップ1「臓器移植における新規技術・機器の導入」高圧下過冷却状態での革新的臓器保存法-前臨床クラウン系ミニブタモデルによる開発  

    第51回日本移植学会総会 

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    Event date: 2015.10

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:熊本市  

  • Yamada K, Sekijima M, Kawai A, Sahara H, Shimizu A   Chimeric thymus versus antigen presenting thymus for the induction of tolerance: donors DCs in vascularized thymus grafts play an essential role in the induction of tolerance.   International conference

    The 14th Congress of the Asian Society of Transplantation 

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    Event date: 2015.8

    Language:English   Presentation type:Oral presentation (general)  

    Venue:Singapore  

  • Sahara H, Iwanaga T, Sekijima M, Waki S, Ichinari Y, Shimizu A, Yamada K   MHC-inbred CLAWN miniature swine as preclinical large animal model for transplantation.   International conference

    The 14th Congress of the Asian Society of Transplantation 

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    Event date: 2015.8

    Language:English   Presentation type:Poster presentation  

    Venue:Singapore  

  • Sekijima M, Tasaki M, Sahara H, Shimizu A, Yamada K   Thymic transplantation to determine mechanisms of thymic involution: Insulin-like growth factor 1 receptor and forkhead box protein N1 in the thymus play a role in maintaining the juvenile thymus.   International conference

    The 14th Congress of the Asian Society of Transplantation 

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    Event date: 2015.8

    Language:English   Presentation type:Oral presentation (general)  

    Venue:Singapore  

  • Sahara H, Sekijima M, Ichinari Y, Iwanaga T, Waki S, Shimizu A, Yamada K   Beneficial effects of hydrogen sulfide on reducing ischemia-reperfusion injury and prolonging pulmonary allograft survival of fully MHC-disparate lung in CLAWN miniature swine.   International conference

    The 14th Congress of the Asian Society of Transplantation 

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    Event date: 2015.8

    Language:English   Presentation type:Oral presentation (general)  

    Venue:Singapore  

  • Sahara H, Nagashima H, Sekijima M, Miura K, Kawai A, Waki S, Nakano K, Matsunari H, Date H, Shimizu A, Yamada K   Carbon monoxide attenuates hyperacute dysfunction and microangiopathy in GalT‐KO pulmonary xenotransplantation.   International conference

    International Society for Heart and Lung Transplantation 35th Annual Meeting 

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    Event date: 2015.4

    Language:English   Presentation type:Poster presentation  

    Venue:Nice  

  • Sahara H, Sekijima M, Waki S, Ichinari Y, Shimizu A, Yamada K   Hydrogen sulfide (H2S) prevents ischemia‐reperfusion injury (IRI) and prolongs survival of the fully MHC‐disparate lung graft in CLAWN miniature swine.   International conference

    International Society for Heart and Lung Transplantation 35th Annual Meeting 

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    Event date: 2015.4

    Language:English   Presentation type:Oral presentation (general)  

    Venue:Nice  

  • 佐原寿史、山田和彦   「医用ミニブタを用いた前臨床研究」クラウンミニブタを用いた移植モデルとMedical Gas  

    先進医用ミニブタの開発と前臨床研究拠点プロジェクト第3回シンポジウム  先進医用ミニブタの開発と前臨床研究拠点プロジェクト第3回シンポジウム

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    Event date: 2015.3

    Language:Japanese   Presentation type:Symposium, workshop panel (nominated)  

    Venue:鹿児島  

    研究会

  • 関島光裕、佐原寿史、山田和彦   膵島移植シンポジウム.Induction of tolerance by composite islet-kidney grafts in non-human primates.  

    第42回日本膵・膵島移植研究会 

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    Event date: 2015.3

    Language:English   Presentation type:Symposium, workshop panel (public)  

    Venue:東京都  

  • 佐原寿史、山田和彦   シンポジウム(7)「異種移植」.前臨床異種移植研究の進歩と課題  

    第41回日本臓器保存生物医学会学術集会  第41回日本臓器保存生物医学会学術集会

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    Event date: 2014.11

    Language:Japanese   Presentation type:Symposium, workshop panel (nominated)  

    Venue:大阪  

    国内学会

  • 佐原寿史、山田和彦   シンポジウム「医薬品および医療機器開発へのブタの活用と今後」.前臨床移植実験としての異種移植研究の進歩と課題  

    第2回日本先進医工学ブタ研究会  第2回日本先進医工学ブタ研究会

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    Event date: 2014.10

    Language:Japanese   Presentation type:Symposium, workshop panel (nominated)  

    Venue:三島  

    研究会

  • 脇 詩織、佐原寿史、関島光裕、市成ゆりか、三井 薫、三浦直樹、瀬戸山健太郎、棈松昌彦、山田和彦   移植医療の新規開発を目指したMHC確立クラウン系ミニブタを用いた前臨床移植実験  

    第2回日本先進医工学ブタ研究会 

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    Event date: 2014.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:三島市  

  • 関島光裕、佐原寿史、脇 詩織、市成ゆりか、清水 章、山田和彦   シンポジウム「医薬品および医療機器開発へのブタの活用と今後」.移植医療の新規開発を目指したMHC確立クラウン系ミニブタを用いた前臨床移植実験   International conference

    第2回日本先進医工学ブタ研究会 

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    Event date: 2014.10

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:三島市  

  • Sahara H, Miura K, Waki S, Kawai A, Shimizu A, Yamada K.   Establishment of clinically applicable strategy of CO therapy - Beneficial effects of inhaled carbon monoxide to brain-dead donors on prolonging pulmonary allograft survival in MHC-inbred CLAWN miniature swine.   International conference

    World Transplant Congress 2014 

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    Event date: 2014.7

    Language:English   Presentation type:Oral presentation (general)  

    Venue:アメリカ合衆国  

    国際学会

  • Sahara H, Miura K, Waki S, Kawai A, Shimizu A, Yamada K.   Hydrogen sulfide therapy prolongs survival of the fully MHC-disparate lung graft from brain-dead donors in CLAWN miniature swine.   International conference

    World Transplant Congress 2014 

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    Event date: 2014.7

    Language:English   Presentation type:Poster presentation  

    Venue:アメリカ合衆国  

    国際学会

  • 佐原寿史、山田和彦   シンポジウム「肺移植の現況と将来展」GalT-KOブタ・カニクイザル間異種肺移植実験の現状 - 異種腎臓移植との比較による治療標的の解明と対策  

    第31回日本呼吸器外科学会総会  第31回日本呼吸器外科学会総会

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    Event date: 2014.5

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:東京  

    国内学会

  • 佐原寿史、三浦宏平、河合昭浩、脇 詩織、清水 章、山田和彦   MHC確立ミニブタ肺移植モデルを用いた新規ドナー臓器保護剤としての硫化水素の可能性評価   Invited

    第31回日本呼吸器外科学会総会 

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    Event date: 2014.5

    Language:Japanese   Presentation type:Oral presentation (general)  

  • 佐原寿史   MHC確立クラウンミニブタによる新規治療・医療機器開発を目指す前臨床試験  

    BIO tech 2014 アカデミーフォーラム  BIO tech 2014 アカデミーフォーラム

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    Event date: 2014.5

    Language:Japanese   Presentation type:Public lecture, seminar, tutorial, course, or other speech  

    Venue:東京  

    その他

  • Sahara H, Miura K, Kawai A, Waki S, Shimizu A, Yamada K   Medical gas (carbon monoxide, hydrogen sulfide) therapy prolongs survival of the fully MHC-disparate lung graft from brain-dead donors in miniature swine.   International conference

    International Society for Heart and Lung Transplantation 34th Annual Meeting  International Society for Heart and Lung Transplantation 34th Annual Meeting

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    Event date: 2014.4

    Language:English   Presentation type:Oral presentation (general)  

    Venue:アメリカ  

    国際学会

  • 三浦宏平、佐原寿史、河合昭浩、脇 詩織、清水 章、山田和彦   MHC 確立クラウンミニブタ小腸移植手技の工夫   Invited

    第114回日本外科学会定期学術集会 

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    Event date: 2014.4

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:京都  

  • 佐原寿史、岩永健裕、山田和彦   シンポジウム2「各系統実験用ブタ紹介」MHC確立クラウン系ミニブタを用いた同種移植実験  

    第1回日本先進医工学ブタ研究会  第1回日本先進医工学ブタ研究会

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    Event date: 2013.11

    Language:Japanese   Presentation type:Symposium, workshop panel (nominated)  

    Venue:大阪  

    研究会

  • Sahara H, Nagashima H, Miura K, Waki S, Kawai A, Nakano K, Matsunari H, Arai Y, Sekijima M, Tasaki M, Setoyama K, Shimizu A, Date H, Yamada K   Attenuation of hyperacute dysfunction and microangiopathy by the treatment of carbon monoxide in GalT-KO pulmonary xenotransplantation.   International conference

    12th Congress IXA (International Xenotransplantation Association 2013)  12th Congress IXA (International Xenotransplantation Association 2013)

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    Event date: 2013.11

    Language:English   Presentation type:Oral presentation (general)  

    Venue:大阪  

    国際学会

  • Sahara H, Yamada K   Symposium. Recent progress in major research laboratories in East Asia - Preclinical Study - “Preclinical large animal xenotransplantation projects in Kagoshima”.   International conference

    The 2nd Symposium of the East Asia Xenotransplantation Association   The 2nd Symposium of the East Asia Xenotransplantation Association

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    Event date: 2013.11

    Language:English   Presentation type:Symposium, workshop panel (nominated)  

    Venue:大阪  

    国際学会

  • 佐原寿史、三浦宏平、河合昭浩、脇詩織 清水 章、山田和彦   MHC確立クラウンミニブタを用いた肺移植実験系によるドナーコンディションと移植後成績の評価およびドナー臓器保護に基づく新規治療法の開発  

    第66回日本胸部外科学会定期学術集会 

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    Event date: 2013.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:仙台市  

  • 佐原寿史、三浦宏平、河合昭浩、脇詩織 清水 章、山田和彦   ドナー臓器修復に基づく新たな移植成績向上戦略のMHC確立クラウンミニブタ肺移植モデルによる評価と有用性   Invited

    第49回日本移植学会総会 

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    Event date: 2013.9 - 2015.9

    Language:Japanese   Presentation type:Poster presentation  

    Venue:京都市  

  • 河合昭浩、佐原寿史、関島光裕、三浦宏平、脇詩織、清水章、山田和彦   MHC確立ミニブタ前臨床腎移植モデルを用いた温虚血障害腎に対する常温臓器保存の有効性の検討  

    第49回日本移植学会総会 

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    Event date: 2013.9

    Language:Japanese   Presentation type:Poster presentation  

  • 脇詩織、佐原寿史、三浦宏平、河合昭浩、田崎正行、清水章、山田和彦   GalT-KOブタ・霊長類間異種腎臓移植の拒絶反応におけるブタサイトメガロウィルス(pCMV)の関与  

    第49回日本移植学会総会 

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    Event date: 2013.9

    Language:Japanese   Presentation type:Poster presentation  

    Venue:京都市  

  • 三浦宏平、佐原寿史、脇詩織、河合昭浩、清水章、山田和彦   脳死ドナーに対する一酸化炭素(CO)吸入によるMHC完全不適合クラウンミニブタ移植肺生着延長効果   Invited

    第49回日本移植学会総会 

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    Event date: 2013.9

    Language:Japanese   Presentation type:Poster presentation  

    Venue:京都市  

  • Sahara H, Nagashima H, Sekijima M, Tasaki M, Setoyama K, Matsunari H, Nakano K, Date H, Shimizu A, Yamada K   Attenuation of hyperacute dysfunction and coagulopathy in GalT-KO pulmonary xenotransplantation.   International conference

    The 13th Congress of the Asian Society of Transplantation  The 13th Congress of the Asian Society of Transplantation

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    Event date: 2013.9

    Language:English   Presentation type:Poster presentation  

    Venue:京都  

    国際学会

  • Sahara H, Miura K, Kawai A, Waki S, Okumi M, Sekijima M, Tasaki M, Oku M, Nishimura H, Shimizu A, Yamada K   MHC-inbred CLAWN miniature swine is a highly valuable preclinical model for transplantation and regenerative medicine.   International conference

    The 13th Congress of the Asian Society of Transplantation  The 13th Congress of the Asian Society of Transplantation

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    Event date: 2013.9

    Language:English   Presentation type:Oral presentation (general)  

    Venue:京都  

    国際学会

  • Miura K, Sahara H, Waki S, Kawai A, Shimizu A, Yamada K   Beneficial effects of inhaled carbon monoxide (CO) to brain-dead (BD) donors on prolonging pulmonary allograft survival in MHC-inbred CLAWN miniature swine.   International conference

    The 13th Congress of the Asian Society of Transplantation  The 13th Congress of the Asian Society of Transplantation

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    Event date: 2013.9

    Language:English   Presentation type:Poster presentation  

    Venue:京都  

    国際学会

  • Kawai A, Sahara H, Sekijima M, Miura K, Waki S, Shimizu A, Yamada K   Potential benefit of subnormothermic preservation for transplanting kidneys which experience extended warm ischemic time in large animal model.   International conference

    The 13th Congress of the Asian Society of Transplantation  The 13th Congress of the Asian Society of Transplantation

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    Event date: 2013.9

    Language:English   Presentation type:Poster presentation  

    Venue:京都  

    国際学会

  • 佐原寿史、三浦宏平、河合昭浩、脇詩織、清水 章、山田和彦   ドナー臓器修復に基づく新たな移植成績向上戦略のMHC確立クラウンミニブタ肺移植モデルによる評価と有用性  

    第49回日本移植学会総会  第49回日本移植学会総会

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    Event date: 2013.9

    Language:Japanese  

    Venue:京都  

    国内学会

  • Sahara H, Miura K, Kawai A, Waki S, Sekijima M, Shimizu A, Yamada K   Carbon monoxide (CO) inhalation prolongs survival of the fully MHC-disparate lung graft from brain death donors in miniature swine.   International conference

    International Society for Heart and Lung Transplantation 33rd Annual Meeting  International Society for Heart and Lung Transplantation 33rd Annual Meeting

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    Event date: 2013.4

    Language:English   Presentation type:Poster presentation  

    Venue:アメリカ  

    国際学会

  • 山田和彦、佐原寿史   シンポジウム4「臓器保存から臓器蘇生へ-温度を考える」Strategies to reduce ischemia-reperfusion injury (IRI) for expansion of usage of marginal donor organs in a preclinical large animal model of CLAWN miniature swine   Invited

    第39回日本低温医学会総会 

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    Event date: 2012.11

    Language:Japanese   Presentation type:Symposium, workshop panel (nominated)  

  • 山田和彦、佐原寿史   教育講演Ⅱ.大動物を用いた前臨床虚血再灌流傷害モデルの作成とマージナルドナー臓器活用戦略   Invited

    第39回日本臓器保存生物医学会学術集会 

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    Event date: 2012.11

    Language:Japanese   Presentation type:Symposium, workshop panel (nominated)  

    Venue:福島市  

  • 佐原寿史、関島光裕、田﨑正行、奥見雅由、屋万栄、西村博昭、瀬戸山健太郎、三浦宏平、河合昭浩、脇詩織、清水章、山田和彦   虚血再灌流障害が移植肺長期生着に及ぼす影響のMHC適合間ミニブタ肺移植モデルによる検討  

    第65回日本胸部外科学会定期学術集会  第65回日本胸部外科学会定期学術集会

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    Event date: 2012.10

    Language:Japanese  

    Venue:福岡  

    国内学会

  • 佐原寿史、関島光裕、田﨑正行、三浦宏平、河合昭浩、脇 詩織、長嶋比呂志、伊達洋至、清水 章、山田和彦   ワークショップ【臓器移植に対する先端研究-次世代の実現を目指す戦略-】臓器特異性に基づく新たな異種免疫反応制御戦略-前臨床ブタ・サル移植モデルによる検討.  

    第48回日本移植学会総会  第48回日本移植学会総会

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    Event date: 2012.9

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:名古屋  

    国内学会

  • Sahara H, Shimizu A, Sekijima M, Setoyama K, Oku M, Nishimura H, Yamada K   High-Mobility Group Box-1 as a novel therapeutic target for reducing pulmonary ischemia-reperfusion injury in CLAWN miniature swine.   International conference

    24th International Congress of the Transplantation Society  24th International Congress of the Transplantation Society

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    Event date: 2012.7

    Language:English   Presentation type:Poster presentation  

    Venue:ドイツ  

    国際学会

  • Sahara H, Sekijima M, Tasaki M, Oku M, Nishimura H, Iwanaga T, Iwanaga T, Sekijima A, Setoyama K, Shimizu A, Yamada K   Carbon monoxide administered only to the donor is sufficient to prolong pulmonary allograft survival across a fully MHC-mismatched barrier in CLAWN miniature swine.   International conference

    24th International Congress of the Transplantation Society  24th International Congress of the Transplantation Society

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    Event date: 2012.7

    Language:English   Presentation type:Oral presentation (general)  

    Venue:ドイツ  

    国際学会

  • Sahara H, Nagashima H, Sekijima M, Tasaki M, Setoyama K, Matsunari H, Nakano K, Date H, Shimizu A, Yamada K   Attenuation of hyperacute dysfunction and coagulopathy in GalT-KO pulmonary xenotransplantation.   International conference

    24th International Congress of the Transplantation Society  24th International Congress of the Transplantation Society

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    Event date: 2012.7

    Language:English   Presentation type:Oral presentation (general)  

    Venue:ドイツ  

    国際学会

  • Sekijima M, Sahara H, Nishimura H, Oku M, Shimizu A, Yamada K   High-mobility group box-1 release induced by renal warm ischemia mediates progression of ischemia-reperfusion injury in miniature swine.   International conference

    24th International Congress of the Transplantation Society  24th International Congress of the Transplantation Society

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    Event date: 2012.7

    Language:English   Presentation type:Oral presentation (general)  

    Venue:ドイツ  

    国際学会

  • Sekijima M, Sahara H, Shimizu A, Iwanaga T, Iwanaga T, Oku M, Yamada K.   Effects of static subnormothermic preservation following warm ischemia on ischemia-reperfusion injury and long-term outcome of the renal allograft in CLAWN miniature swine.   International conference

    24th International Congress of the Transplantation Society  24th International Congress of the Transplantation Society

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    Event date: 2012.7

    Language:English   Presentation type:Oral presentation (general)  

    Venue:ドイツ  

    国際学会

  • 佐原寿史、清水 章、関島光裕、田﨑正行、瀬戸山健太郎、長嶋比呂志、伊達洋至、山田和彦   GalT-KOブタ肺による急性期グラフト機能不全抑制効果の体外循環肺移植モデルによる評価  

    第29回日本呼吸器外科学会総会  第29回日本呼吸器外科学会総会

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    Event date: 2012.5

    Language:Japanese  

    Venue:秋田  

    国内学会

  • Sahara H, Shimizu A, Sekijima M, Setoyama K, Oku M, Nishimura H, Yamada K   Protective effect of anti-high-mobility group box-1 (HMGB1) antibody on pulmonary ischemia-reperfusion injury in miniature swine.   International conference

    International Society for Heart and Lung Transplantation 32nd Annual Meeting  International Society for Heart and Lung Transplantation 32nd Annual Meeting

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    Event date: 2012.4

    Language:English   Presentation type:Oral presentation (general)  

    Venue:チェコ  

    国際学会

  • Sahara H, Shimizu A, Tasaki M, Sekijima M, Oku M, Nishimura H, Iwamoto E, Setoyama K, Yamada K   Donor preconditioning with carbon monoxide (CO) prolongs lung graft survival in miniature swine.   International conference

    International Society for Heart and Lung Transplantation 32nd Annual Meeting  International Society for Heart and Lung Transplantation 32nd Annual Meeting

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    Event date: 2012.4

    Language:English   Presentation type:Oral presentation (general)  

    Venue:チェコ  

    国際学会

  • 佐原寿史、関島光裕、田﨑正行、屋万栄、瀬戸山健太郎、清水章、山田和彦   平成 22 年度日本臓器保存生物医学会研究奨励賞 受賞記念講演 「移植肺生着延長に寄与するドナー臓器保護方法としての一酸化炭素(CO)投与療法-前臨床ミニブタモデルを用いた新たな臓器保存方法への発展」  

    第38回日本臓器保存生物医学会学術集会  第38回日本臓器保存生物医学会学術集会

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    Event date: 2011.11

    Language:Japanese   Presentation type:Symposium, workshop panel (nominated)  

    Venue:仙台  

    国内学会

  • Sahara H, Nagashima H, Sekijima M, Tasaki M, Setoyama K, Matsunari H, Nakano K, Date H, Shimizu A, Yamada K   Prevention of hyper-acute pulmonary xenograft dysfunction using GalT-KO swine in an ex-vivo lung perfusion model   International conference

    CTS (Cell Transplant Society) -IXA (International Xenotransplantation Association) 2011 Joint Congress  CTS (Cell Transplant Society) -IXA (International Xenotransplantation Association) 2011 Joint Congress

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    Event date: 2011.10

    Language:English   Presentation type:Oral presentation (general)  

    Venue:アメリカ合衆国  

    国際学会

  • Tasaki M, Sahara H, Okitsu T, Oku M, Nishimura H, Sekijima M, Setoyama K, Shimizu A, Yamada K   Prolongation of xenoegeneic islet function using an HGF-based immunosuppressive regimen in a CLAWN miniature swine-to-cynomologous monkey model   International conference

    CTS (Cell Transplant Society) -IXA (International Xenotransplantation Association) 2011 Joint Congress  CTS (Cell Transplant Society) -IXA (International Xenotransplantation Association) 2011 Joint Congress

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    Event date: 2011.10

    Language:English   Presentation type:Oral presentation (general)  

    Venue:アメリカ合衆国  

    国際学会

  • 佐原寿史、清水 章、関島光裕、田﨑正行、瀬戸山健太郎、長嶋比呂志、伊達洋至、山田和彦   体外循環回路を用いたEx-vivo GalT-KOブタ肺移植モデルによる急性期グラフト機能不全抑制効果の評価  

    第64回日本胸部外科学会定期学術集会 

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    Event date: 2011.10

    Language:Japanese   Presentation type:Oral presentation (general)  

  • 佐原寿史、長嶋比呂志、齋藤敏樹、島津美樹、伊達洋至、清水 章、山田和彦   シンポジウム2.次世代の移植医療に向けて:先端技術を応用した移植医療の開発 「臨床応用を目指したブタ・サル間異種移植実験」  

    第47回日本移植学会総会  第47回日本移植学会総会

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    Event date: 2011.10

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:仙台  

    国内学会

  • Iwanaga T, Sahara H, Okumi M, Iwanaga T, Tasaki M, Sekijima M, Tottori J, Yamada K   MHC-inbred CLAWN miniature swine: a highly valuable preclinical model for transplantation   International conference

    12th Congress of the Asian Society of Transplantation  12th Congress of the Asian Society of Transplantation

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    Event date: 2011.9

    Language:English   Presentation type:Oral presentation (general)  

    Venue:韓国  

    国際学会

  • Iwamoto E, Sahara H, Nishimura H, Sekijima M, Sekijima A, Oku M, Scalea J, Shimizu A, Yamada K   Anti-high-mobility group box-1 antibody reduces renal ischemia-reperfusion injury in miniature swine   International conference

    12th Congress of the Asian Society of Transplantation  12th Congress of the Asian Society of Transplantation

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    Event date: 2011.9

    Language:English   Presentation type:Oral presentation (general)  

    Venue:韓国  

    国際学会

  • Sekijima M, Tasaki M, Sahara H, Shimizu A, Oku M, Nishimura H, Scalea J, Tsubouchi H, Yamada K   Xenogeneic islet transplantation using an HGF-based immunosuppressive regimen in a CLAWN miniature swine-to-cynomologous monkey model   International conference

    12th Congress of the Asian Society of Transplantation  12th Congress of the Asian Society of Transplantation

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    Event date: 2011.9

    Language:English   Presentation type:Oral presentation (general)  

    Venue:韓国  

    国際学会

  • Sekijima M, Sahara H, Oku M, Shimizu A, Okumi M, Nishimura H, Scalea J, Tsubouchi H, Yamada K   Hepatocyte growth factor sustains Tregs and prolongs the survival of kidney allografts in MHC-inbred CLAWN-miniature swine   International conference

    12th Congress of the Asian Society of Transplantation  12th Congress of the Asian Society of Transplantation

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    Event date: 2011.9

    Language:English   Presentation type:Oral presentation (general)  

    Venue:韓国  

    国際学会

  • Sahara H, Shimizu A, Tasaki M, Sekijima M, Oku M, Nishimura H, Iwamoto E, Setoyama K, Yamada K   Donor preconditioning with carbon monoxide prevents pulmonary allograft injury and prolongs survival in miniature swine   International conference

    12th Congress of the Asian Society of Transplantation  12th Congress of the Asian Society of Transplantation

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    Event date: 2011.9

    Language:English   Presentation type:Poster presentation  

    Venue:韓国  

    国際学会

  • Sahara H, Shimizu A, Setoyama K, Oku M, Nishimura H, Yamada K   Protective effect of neutralization of the extracellular high-mobility group box-1 on pulmonary ischemia-reperfusion injury in miniature swine   International conference

    12th Congress of the Asian Society of Transplantation  12th Congress of the Asian Society of Transplantation

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    Event date: 2011.9

    Language:English   Presentation type:Oral presentation (general)  

    Venue:韓国  

    国際学会

  • 佐原寿史、田﨑正行、屋 万栄、関島光裕、瀬戸山健太郎、清水 章、山田和彦   ドナー一酸化炭素吸入のみでのミニブタ移植肺生着延長効果  

    第28回日本呼吸器外科学会総会 

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    Event date: 2011.5

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:別府市  

  • Sahara H, Shimizu A, Tasaki M, Oku M, Nishimura N, Setoyama K, Yamada K   Treatment of only the donor with carbon monoxide (CO) prolongs pulmonary allograft survival in miniature swine   International conference

    International Society for Heart and Lung Transplantation 31st Annual Meeting  International Society for Heart and Lung Transplantation 31st Annual Meeting

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    Event date: 2011.4

    Language:English   Presentation type:Poster presentation  

    Venue:アメリカ合衆国  

    国際学会

  • 佐原寿史、田﨑正行、西村博昭、屋 万栄、瀬戸山健太郎、清水 章、山田和彦   一酸化炭素(CO)吸入療法によるミニブタ移植肺生着延長効果:臨床応用を目指した治療戦略  

    第63回日本胸部外科学会定期学術集会 

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    Event date: 2010.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:大阪市  

  • 佐原寿史、屋 万栄、田﨑正行、西村博昭、瀬戸山健太郎、Oriyanhan Wunimenghe、奥見雅由、清水 章、山田和彦   「ワークショップ5.移植免疫における新たな試み」MHC確立クラウン系ミニブタ大動物同種移植モデルを用いた移植免疫学的機序にに基づく新たな治療戦略の確立  

    第46回日本移植学会総会  第46回日本移植学会総会

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    Event date: 2010.10

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:京都  

    国内学会

  • 山田和彦、島津美樹、田﨑正行、堀井 渉、西村博昭、齋藤敏樹、佐原寿史、布谷鉄夫   国内初のミニブタ(NIBS系)をクローン胚移植用レシピエントとしたGalT-KOミニブタの作出とGalT-KOブタ・サル異種間腎移植  

    第46回日本移植学会総会 

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    Event date: 2010.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:京都市  

  • 田﨑正行、西村博昭、興津 輝、屋 万栄、佐原寿史、山田和彦   ブタ・サル異種間膵島移植:クラウンブタ膵島異種移植後2ヶ月間の正常血糖維持  

    第46回日本移植学会総会 

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    Event date: 2010.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:京都市  

  • Sahara H, Yamada K   Symposium 3. Basic, kidney, liver. Translational research of carbon monoxide (CO) therapy for prolonging pulmonary allograft survival using MHC-inbred CLAWN miniature swine   International conference

    The 8th Japan-Korea Transplantation Forum  The 8th Japan-Korea Transplantation Forum

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    Event date: 2010.10

    Language:English   Presentation type:Symposium, workshop panel (public)  

    Venue:京都  

    国際学会

  • Yamada K, Nishimura H, Sahara H, Okitsu T, Setoyama K, Oku M, Tasaki M, Wunimenghe O, Griesemer A, Tsubouchi H, Shimizu A   Hepatocyte growth factor regimen in a life supporting xenoegeneic islet transplantation CLAWN miniature swine-to-cynomolgus monkey model   International conference

    XXIII International Congress of the Transplantation Society  XXIII International Congress of the Transplantation Society

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    Event date: 2010.8

    Language:English   Presentation type:Oral presentation (general)  

    Venue:カナダ  

    国際学会

  • Sahara H, Oku M, Setoyama K, Tasaki M, Nishimura H, Oriyanhan W, Okumi M, Shimizu A, Yamada K   Anti-high mobility group box-1 antibodies reduce pulmonary ischemia reperfusion injury in miniature swine   International conference

    XXIII International Congress of the Transplantation Society  XXIII International Congress of the Transplantation Society

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    Event date: 2010.8

    Language:English   Presentation type:Oral presentation (general)  

    Venue:カナダ  

    国際学会

  • Sahara H, Tasaki M, Setoyama K, Nishimura H, Oku M, Shimizu A, Yamada K   Beneficial effects of perioperative low-dose inhalation of carbon monoxide on pulmonary allograft survival in MHC-inbred CLAWN miniature swine   International conference

    XXIII International Congress of the Transplantation Society  XXIII International Congress of the Transplantation Society

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    Event date: 2010.8

    Language:English   Presentation type:Oral presentation (general)  

    Venue:カナダ  

    国際学会

  • 佐原寿史   招待講演:肺移植の臨床及び最先端研究の紹介  

    日本移植者協議会第53回移植セミナー  日本移植者協議会第53回移植セミナー

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    Event date: 2010.7

    Language:Japanese   Presentation type:Public lecture, seminar, tutorial, course, or other speech  

    Venue:鹿児島  

    研究会

  • 佐藤寿彦、阪井宏彰、陳 豊史、佐原寿史、藤永卓司、庄司 剛、園部 誠、宮原 亮、板東 徹、大久保憲一、伊達洋至   「シンポジウム2.間質性肺炎合併肺癌の手術」間質性肺炎合併肺癌の手術 間質性肺炎合併肺癌手術症例の検討  

    第27回日本呼吸器外科学会総会  第27回日本呼吸器外科学会総会

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    Event date: 2010.5

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:仙台  

    国内学会

  • 佐原寿史、瀬戸山健太郎、西村 博昭、田﨑正行、屋 万栄、清水 章、山田和彦   移植肺生着延長効果を目指した至適一酸化炭素(CO)吸入療法のミニブタ肺移植モデルによる検討   International conference

    第27回日本呼吸器外科学会総会 

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    Event date: 2010.5

    Language:Japanese   Presentation type:Poster presentation  

    Venue:仙台市  

  • 藤永卓司、中島大輔、阪本 仁、石川将史、森川洋匡、山田 徹、高橋鮎子、里田直樹、佐藤寿彦、陳 豊史、佐原寿史、庄司 剛、園部 誠、阪井宏彰、宮原 亮、大久保憲一、板東 徹、伊達洋至   造血幹細胞移植後閉塞性細気管支炎に対して施行した生体肺移植症例の検討   International conference

    第27回日本呼吸器外科学会総会 

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    Event date: 2010.5

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:仙台市  

  • Sahara H, Setoyama K, Nishimura H, Oriyanhan W, Shimizu A, Yamada K   Carbon monoxide (CO) prolongs survival of pulmonary allografts in MHC-inbred CLAWN miniature swine   International conference

    International Society for Heart and Lung Transplantation 30th Annual Meeting  International Society for Heart and Lung Transplantation 30th Annual Meeting

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    Event date: 2010.4

    Language:English   Presentation type:Oral presentation (general)  

    Venue:アメリカ合衆国  

    国際学会

  • 佐原寿史   シンポジウム:MHC確立クラウン系ミニブタを用いた移植実験-すでにここまで進んでいる  

    先進医用ミニブタの開発と前臨床研究拠点プロジェクト第1回シンポジウム  先進医用ミニブタの開発と前臨床研究拠点プロジェクト第1回シンポジウム

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    Event date: 2010.2

    Language:Japanese   Presentation type:Symposium, workshop panel (nominated)  

    Venue:鹿児島  

    研究会

  • Oriyanhan W, Nishimura H, Okitsu T, Setoyama K, Sahara H, Oku M, Tsubouchi H, Ishikawa Y, Shimizu A, Yamada K   Life supporting xenogeneic islet transplantation with a regimen including hepatocyte growth factor in a clawn miniature swine-to-cynomologous monkey   International conference

    Joint Meeting of the International Pancreas and Islet Transplant Association (IPITA) and the International Xenotransplantation Association (IXA)  Joint Meeting of the International Pancreas and Islet Transplant Association (IPITA) and the International Xenotransplantation Association (IXA)

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    Event date: 2009.10

    Language:English   Presentation type:Oral presentation (general)  

    Venue:イタリア  

    国際学会

  • 佐原寿史、瀬戸山健太郎、西村博昭、W. Oriyanhan、屋 万栄、奥見雅由、清水 章、山田和彦   「シンポジウム心・肺移植における長期生着阻害因子とその対策」移植肺生着阻害因子としてのMHC差異・虚血再灌流障害(IRI)及び一酸化炭素(CO)吸入を用いた拒絶抑制効果-MHC確立ミニブタ肺移植モデルによる検討  

    第45回日本移植学会総会  第45回日本移植学会総会

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    Event date: 2009.9

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:東京  

    国内学会

  • 山田和彦、石川義典、佐原寿史   「特別シンポジウム:臓器移植における免疫寛容の誘導」 膵島移植免疫寛容誘導の独自戦略:Strategy to induce tolerance to islets  

    第45回日本移植学会総会  第45回日本移植学会総会

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    Event date: 2009.9

    Language:Japanese   Presentation type:Symposium, workshop panel (nominated)  

    Venue:東京  

    国内学会

  • Nishimura H, Oku M, Sahara H, Okumi M, Griesemer A, Shimizu A, Yamada K   Hepatocyte growth factor prolongs allograft survival with maintenance of Treg population in MHC-inbred CLAWN miniature swine   International conference

    American Transplant Congress 2009  American Transplant Congress 2009

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    Event date: 2009.5 - 2009.6

    Language:English   Presentation type:Oral presentation (general)  

    Venue:アメリカ合衆国  

    国際学会

  • Nishimura H, Oku M, Okumi M, Sahara H, Setoyama K, Oriyanhan W, Shimizu A, Yamada K   Hepatocyte growth factor prolongs allograft survival with maintenance of Treg population in MHC-inbred CLAWN miniature swine   International conference

    104th American Urological Association Annual Meeting  104th American Urological Association Annual Meeting

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    Event date: 2009.4

    Language:English  

    Venue:アメリカ合衆国  

    国際学会

  • Sahara H, Oku M, Okumi M, Setoyama K, Shimizu A, Yamada K   Carbon monoxide inhalation reduces pulmonary ischemia-reperfusion injury in miniature swine   International conference

    International Society for Heart and Lung Transplantation 28th Annual Meeting and Scientific Sessions  International Society for Heart and Lung Transplantation 28th Annual Meeting and Scientific Sessions

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    Event date: 2009.4

    Language:English  

    Venue:フランス  

    国際学会

  • 佐原寿史, 奥見雅由, 屋 万栄, 瀬戸山健太郎, 西村博昭, Oriyanhan W, 清水 章, 山田和彦   「シンポジウム」クラウン系ミニブタモデルを用いた一酸化炭素吸入の肺虚血再灌流障害抑制効果及び HMGB1に焦点をあてた作用機序の解明一早期臨床応用を目指した大動物モデルによる検討とその発展.  

    第35回日本臓器保存生物医学会定期学術集会 

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    Event date: 2008.11

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:東京  

    国内学会

  • Oku M, Okumi M, Sahara H, Griesemer A, Tsubouchi H, Shimizu A, Yamada K   Hepatocyte growth factor sustains the Treg population and prolongs survival of kidney allografts in MHC-inbred CLAWN miniature swine.   International conference

    The American Society of Nephrology Renal Week 2008 

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    Event date: 2008.11

    Language:English   Presentation type:Oral presentation (general)  

    Venue:アメリカ合衆国  

    国際学会

  • Oku M, Okumi M, Sahara H, Tsubouchi H, Shimizu A, Sada M, Yamada K   Maintenance of Treg population and prolongation of allograft survival by hepatocyte growth factor in MHC-inbred CLAWN miniature swine.   International conference

    XXII International Congress of the Transplantation Society 

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    Event date: 2008.8

    Language:English   Presentation type:Oral presentation (general)  

    Venue:オーストラリア  

    国際学会

  • Sahara H, Oku M, Okumi M, Setoyama K, Shimizu A, Yamada K   Beneficial effects of carbon monoxide on ischemia-reperfusion injury of lung in miniature swine.   International conference

    XXII International Congress of the Transplantation Society 

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    Event date: 2008.8

    Language:English   Presentation type:Poster presentation  

    Venue:オーストラリア  

    国際学会

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