Updated on 2023/04/22

写真a

 
OKAMOTO Shigehisa
 
Organization
Research Field in Agriculture, Agriculture, Fisheries and Veterinary Medicine Area Faculty of Agriculture Department of Agriculture Associate Professor
Research Field in Agriculture, Agriculture, Fisheries and Veterinary Medicine Area United Graduate School of Agricultural Sciences
Title
Associate Professor

Degree

  • 理学博士 ( 1990.3   名古屋大学 )

  • 理学修士 ( 1986.3   名古屋大学 )

Research Interests

  • Signal transduction

  • Gene expression

  • Bioactive substance

  • Plant hormone

  • Differentiation

  • Development

  • Molecular Breeding

  • 発生分化

  • 植物・微生物相互座用

  • 植物ホルモン

  • 分子育種

  • ストレス耐性

  • Phytohormone

Research Areas

  • Life Science / Plant molecular biology and physiology

Education

  • Nagoya University   Graduate School, Division of Natural Science   Biology

    - 1990

  • Nagoya University

    - 1990

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    Country： Japan

  • Nagoya University   Faculty of Science   Biology

    - 1984

  • Nagoya University   School of Science

    - 1984

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    Country： Japan

Research History

  • - 鹿児島大学農学部 准教授

    2007

  • - Associate Professor, Faculty of Agriculture, Kagoshima University

    2004

  • Kagoshima University   Research Field in Agriculture, Agriculture, Fisheries and Veterinary Medicine Area Faculty of Agriculture Department of Biochemical Science and Technology   Associate Professor

    1993.1

  • Kagoshima University

    1993.1

Professional Memberships

  • 日本園芸学会

    2015.10

  • 日本農芸化学会

    2015.10

  • 日本植物学会

    2015.10

  • 日本植物生理学会

    2015.10

  • 日本分子生物学会

    2015.10

  • 植物化学調節学会

  • 日本農芸化学会

  • 日本植物生理学会

  • 日本植物学会

  • 日本分子生物学会

  • 園芸学会

  • The Molecular Biology Society of Japan

  • The Japanese Society of Plant Physiologists

  • The Japanese Society for Horticultural Science

  • The Japanese Society for Chemical Regulation of Plants

  • The Japan Society for Bioscience

  • The Botanical Society of Japan

  • The American Society of Plant Biologists

  • American Society of Plant Biologists

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Papers

  • Kamimura Miyu, Sasaki Azusa, Otani Yui, Nakamura Yasushi, Nakamura Takako, Kuramochi Kouji, Imai Toshio, Kubo Nakao, Okamoto Shigehisa .  Methylthioacetic acid, a derivative of aroma compounds from <i>Cucumis melo</i> var. <i>conomon</i> dose-dependently triggers differentiation and apoptosis of RCM-1 human colorectal cancer cells .  The Journal of Toxicological Sciences48 ( 1 ) 25 - 35   2023.1Reviewed International journal

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    Authorship：Last author,　Corresponding author   Language：English   Publishing type：Research paper (scientific journal)   Publisher：The Japanese Society of Toxicology  

    <p>Methylthioacetic acid (MTA) is an acid-hydrolyzed derivative of a natural aroma compound, methylthioacetic acid ethyl ester isolated from <i>Cucumis melo</i> var. <i>conomon</i> (Katsura-uri, Japanese Picking Melon), and induces a villiform-like structure dome in RCM-1 human colorectal cancer cell culture. Thus far, the physiological and molecular properties of MTA-mediated dome formation remain unknown. Herein, MTA (not more than 2 mM) was demonstrated to differentiate the unorganized cell mass into the dome in RCM-1 cell culture by disclosing the correlation between dome formation and several intestinal differentiation markers such as alkaline phosphatase activity and the protein levels of dipeptidyl peptidase 4, villin, and Krüppel-like factor 4. Dome formation in RCM-1 cell culture was additively enhanced by the simultaneous administration of MTA and butyric acid (BA), suggesting that MTA directs the differentiation of RCM-1 cells, potentially through the same or similar pathway(s) shared with BA. Notably, a high dose of MTA (2 mM or more) elevated several apoptosis markers, such as DNA fragmentation, caspase-3/7 activity, and cleavage of poly(ADP-ribose) polymerase. Altogether, in addition to RCM-1 cell differentiation, MTA triggers apoptosis. These results indicate that MTA is a potential anticarcinogenic agent applicable in differentiation therapy and traditional chemotherapy against colorectal cancers.</p>

    DOI： 10.2131/jts.48.25

    DOI： 10.2131/jts.48.25

    Scopus

    PubMed

  • Nakamura T., Nakao A., Watanabe M., Ueda K., Matsuda T., Matsumoto S., Yamaguchi T., Haikata M., Kaneko A., Shirota K., Sasaki A., Okamoto S., Nakamura Y. .  Nationwide distribution of Kyo-yasai (heirloom vegetables in Kyoto) and the advantages of traditional farming methods with importance of ‘Syun’: a case of mizuna .  Journal of Ethnic Foods9 ( 1 )   2022.12Reviewed International journal

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    Language：English   Publishing type：Research paper (scientific journal)   Publisher：Journal of Ethnic Foods  

    Introduction: This study aimed to review the farming activity and the administrative measure to successfully increase the distribution of heirloom vegetable “mizuna” nationwide by examining the paradigm shift in the use of its young less-branched form for salad. We also discussed that breeding programs of the young form ironically resulted in reduction the flavor and the antimutagenicity of this vegetable. Methods: Through hearing survey, we explored reasons for the successful nationwide distribution of heirloom vegetable, mizuna. Through chemical analysis, the fragrant ingredients in mizuna, their antimutagenicity and the changes in their amount for one year were determined. Results and discussion: The primary factor for commencing the distribution of mizuna includes the new idea of using young less-branched form of mizuna as salad ingredient, which has been recognized by most who were involved in promoting the distribution of mizuna among farmers, distributors, and employees of agricultural extension section at Kyoto Prefecture office. The secondary factor is the fact that the primary factor coincides on a time axis with other two factors: the occurrence of the boom of Kyoto's heirloom vegetables and the Vegetable Management Stabilization Project found as a measure of Kyoto Prefecture. We determined three fragrant compounds in mizuna, 3-butenyl isothiocyanate, 3-phenylpropionitrile, and phenylethyl isothiocyanate, of which their antimutagenic effects were also identified. Those amounts were highest at the best harvest season called ‘Syun’ in the past because of the cold temperature of Japanese winter in traditional open-field cultivation. Conclusion: It implied that the successful nationwide distribution of mizuna resulted from the administrative measures based on the paradigm shift in the new use of mizuna for salad due to increase in demand of the vegetable in contemporary dishes. The traditional cultivation of mizuna might be suitable if wishing the flavor and antimutagenicity at the best harvest season ‘Syun’.

    DOI： 10.1186/s42779-022-00141-8

    Scopus

  • Otani Y., Kawanishi M., Kamimura M., Sasaki A., Nakamura Y., Nakamura T., Okamoto S. .  Behavior and possible function of Arabidopsis BES1/BZR1 homolog 2 in brassinosteroid signaling .  Plant Signaling and Behavior17 ( 1 ) 2084277-1 - 2084277-10   2022.7Reviewed International journal

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    Authorship：Last author,　Corresponding author   Language：English   Publishing type：Research paper (scientific journal)   Publisher：Taylor & Francis  

    Two key transcription factors (TFs) in brassinosteroid (BR) signaling BRASSINOSTEROID INSENSITIVE 1-EMS-SUPPRESSOR 1 (BES1) and BRASSINAZOLE RESISTANT 1 (BZR1), belong to a small family with four BES1/BZR1 homologs (BEH1–4). To date, in contrast to the wealth of knowledge regarding BES1 and BZR1, little is known about BEH1–4. Here, we show that BEH2 was expressed preferentially in the roots and leaf margins including serrations, which was quite different from another member BEH4, and that BRs downregulated BEH2 through a module containing GSK3-like kinases and BES1/BZR1 TFs, among which BES1, rather than BZR1, contributed to this process. In addition, BEH2 consistently existed in the nucleus, suggesting that its subcellular localization is not under BR-dependent nuclear-cytoplasmic shuttling control. Furthermore, gene ontology analysis on RNA-seq data indicated that BEH2 may be implicated in stress response and photosynthesis. These findings might assist in the future elucidation of the molecular mechanisms underlying BR signaling.

    DOI： 10.1080/15592324.2022.2084277

    Scopus

    PubMed

  • Fukui Yuri, Saito Moeko, Nakamura Natsuno, Mizuno Taichi, Sato Shuichi, Tsukuda Mayu, Nakaoka Saori, Tsuboi Keita, Sasaki Azusa, Kuramochi Kouji, Boonyaritthongchai Panida, Kaewmanee Nichapat, Thirapanmethee Krit, Chomnawang Mullika Traidej, Bongcheewin Bhanubong, Nguyen Thuy Linh, Nguyen Huong Lan Thi, Le Huong Thi, Okamoto Shigehisa, Nakamura Takako, Nakamura Yasushi, Kubo Nakao .  Classification of Southeast Asian mints (<i>Mentha</i> spp.) based on simple sequence repeat markers .  Breeding Science72 ( 2 ) 181 - 187   2022Reviewed International coauthorship International journal

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    Language：English   Publishing type：Research paper (scientific journal)   Publisher：Japanese Society of Breeding  

    <p><i>Mentha</i> is a complex genus encompassing many species as a consequence of their interspecific hybridization and polyploidy. Southeast Asian mints have been poorly distinguished though they are widely used for culinary and medical purposes. In this study, we have analyzed Southeast Asian mints and known varieties as well as a related Lamiaceae species (<i>Nepeta</i> sp.) using simple sequence repeat (SSR) markers and leaf morphology. Two types of mints were clearly distinguished based on their venation pattern and leaf shape index. We developed 12 SSR markers that allowed good amplification in the <i>Mentha</i> and another Lamiaceae species. In the SSR-based phylogram, the <i>Mentha</i> lines could be delimited into groups I–VI. The Southeast Asian mints divided into groups I and II, and the phylogram separated most of the available species, with groups I and II containing the known species <i>M.</i> × <i>cordifolia</i> and <i>M. arvensis</i>, respectively. The separation of the two groups was supported by a population structure analysis. The SSR markers developed in this study enabled the simultaneous classification of mints and will help improve our understanding of the genetic composition of known mint varieties and as yet unclassified Southeast Asian mints.</p>

    DOI： 10.1270/jsbbs.21058

    Scopus

    PubMed

  • Miyu Kamimura Azusa Sasaki Shimpei Watanabe Shiho Tanaka Akiko Fukukawa Kazuya Takeda Yasushi Nakamura Takako Nakamura Kouji Kuramochi Yui Otani Fumio Hashimoto Kanji Ishimaru Tomoaki Matsuo Shigehisa Okamoto .  Chemical and molecular bases of dome formation in human colorectal cancer cells mediated by sulphur compounds from Cucumis melo var. conomon .  FEBS openbio10 ( 12 ) 2640 - 2655   2020.10Chemical and molecular bases of dome formation in human colorectal cancer cells mediated by sulphur compounds from Cucumis melo var. conomonReviewed

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    Authorship：Corresponding author   Language：English   Publishing type：Research paper (scientific journal)  

  • Sasaki Azusa, Nakamura Yasushi, Kobayashi Yukiko, Aoi Wataru, Nakamura Takako, Shirota Koji, Suetome Noboru, Fukui Michiaki, Matsuo Tomoaki, Okamoto Shigehisa, Tashiro Yuri, Park Eun Young, Sato Kenji .  京都の伝統野菜桂ウリ(Cucumis melo var. conomon)の完熟果実の糖尿病患者への適用(Contribution of Katsura-uri(Japan's Heirloom Pickling Melon, Cucumis melo var. conomon) at the Completely Ripe Stage to Diabetes Control) .  Journal of Nutritional Science and Vitaminology66 ( 3 ) 261 - 269   2020.6京都の伝統野菜桂ウリ(Cucumis melo var. conomon)の完熟果実の糖尿病患者への適用(Contribution of Katsura-uri(Japan's Heirloom Pickling Melon, Cucumis melo var. conomon) at the Completely Ripe Stage to Diabetes Control)

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    Publisher：(公社)日本栄養・食糧学会  

    京都の伝統野菜のひとつである桂ウリ(Cucumis melo var. conomon)は,果実様の香気をもつが甘味がほとんどないため果実としての価値はなかった.これに0kcalの高甘味度甘味料で甘味を付加したジュースは,血糖値の上昇が少ない飲料として利用できる可能性がある.本研究ではその有用性を,糖尿病患者を対象として検討した.桂ウリ果実を5段階の熟度に分類して果実の特性を検討したところ,色差,破断強度,香気成分では熟度間で統計学的有意差があり,食物繊維以外の一般成分,糖では有意差はなかったことから,桂ウリは完熟(ステージ5)しても低糖を維持したまま強い果実様香気を放つ特殊な果実であることが明らかとなった.桂ウリの完熟果実をジュースとし,10名の糖尿病患者(46-75歳)が,これを240g飲用後の血糖値を測定し,対照として同量のメロンジュースを用いた.桂ウリジュース摂取後の血糖値の曲線下面積(16±5h・mg/dL)はメロンジュース摂取後(55±17h・mg/dL)よりも有意に低値であった(p<0.05).また,桂ウリジュース摂取後の血糖値の変動幅(22±5mg/dL)はメロンジュース摂取後(64±6mg/dL)よりも小さかった(p<0.05).これまで高甘味度甘味料を果実に適用する例はなかったが,桂ウリの完熟果実は高甘味度甘味料を添加すると,糖尿病患者が血糖値の上昇を気にせず飲用できるジュース用食材として有用であることが示された.(著者抄録)

  • Yui Otani,1 Yusuke Tomonaga,1 Kenya Tokushige,1 Miyu Kamimura,1 Azusa Sasaki,2 Yasushi Nakamura,3 Takako Nakamura,2 Tomoaki Matsuo1 and Shigehisa Okamoto1* .  Expression profiles of Four BES1/BZR1 homologous genes encoding bHLH transcription factors in Arabidopsis .  Journal of Pesticide Science45 ( 2 ) 95 - 104   2020.4Expression profiles of Four BES1/BZR1 homologous genes encoding bHLH transcription factors in ArabidopsisReviewed

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    Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)   Publisher：日本農薬学会  

    DOI： DOI: 10.1584/jpestics.D20-001

  • Ryohei Sato1, Azusa Sasaki2, Yuko Mori1, Mio Komai2, Shogo Kamo1, Mai Onuki1, Takafumi Seki3, Zen Kawabe1, Shu Miyajima1, Shusuke Tomoshige1, Tsuneomi Kawasaki3, Shuichi Sato2, Takako Nakamura2, Nakao Kubo2, Seiji Takeda2, Shuichi Date2, Shigehisa Okamoto4他 .  Investigation on the Epoxidation of Piperitenone, and Structure–activity Relationships of Piperitenone Oxide for Differentiation-inducing Activity .  Journal of Oleo Science   2020.4Investigation on the Epoxidation of Piperitenone, and Structure–activity Relationships of Piperitenone Oxide for Differentiation-inducing ActivityReviewed

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： doi : 10.5650/jos.ess19278

  • Sasaki A. .  Preparation of contemporary dishes and a functional drink using Japan's heirloom vegetable, Katsura-uri .  Journal of Ethnic Foods5 ( 1 ) 60 - 65   2018.3

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    Publisher：Journal of Ethnic Foods  

    DOI： 10.1016/j.jef.2017.09.001

    Scopus

  • Nakamura T. .  Protection of Kyo-yasai (heirloom vegetables in Kyoto) from extinction: a case of Sabaka-daikon (Japan's heirloom white radish, Raphanus sativus) in Maizuru, Japan .  Journal of Ethnic Foods4 ( 2 ) 103 - 109   2017.6

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    Publisher：Journal of Ethnic Foods  

    DOI： 10.1016/j.jef.2017.05.008

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  • Isamu Suzuki1, 2, Young-Man Cho1*, Tadashi Hirata1, 3, Takeshi Toyoda1, Jun-ichi Akagi1, Yasushi Nakamura4, 5, Eun Young Park4, 6#, Azusa Sasaki4, Takako Nakamura4, Shigehisa Okamoto7他 .  4-Methylthio-3-butenyl isothiocyanate (raphasatin) exerts chemopreventive effects against esophageal carcinogenesis in rats .  Journal of Toxicologic Pathology29   237 - 246   2016.74-Methylthio-3-butenyl isothiocyanate (raphasatin) exerts chemopreventive effects against esophageal carcinogenesis in ratsReviewed

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    Language：English   Publishing type：Research paper (scientific journal)   Publisher：日本毒性病理学会  

    DOI： doi: 10.1293/tox.2016-0037

  • Tomoaki Shigeta, Yuichi Zaizen, Yasushi Sugimoto, Yasushi Nakamura, Tomoaki Matsuo, Shigehisa Okamoto .  Heat shock protein 90 acts in brassinosteroid signaling through interaction with BES1/BZR1 transcription factor .  Journal of Plant Physiology178 ( 15 ) 69 - 73   2015.4Heat shock protein 90 acts in brassinosteroid signaling through interaction with BES1/BZR1 transcription factorReviewed

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  • Nakamura Y, Hasegawa Y, Shirota K, Suetome N, Nakamura T, Chomnawang M, Thirapanmethee K, Khuntayaporn P, Boonyaritthongchai P, Wongs-Aree C, Okamoto S, Shigeta T, Matsuo T, Park EY, and Sato K .  Differentiation-inducing effect of piperitenone oxide, a fragrant ingredient of spearmint (Mentha spicata), but not carvone and menthol, against human colon cancer cells. .  J. Funct. Foods8 ( C ) 62 - 67   2014.1 Differentiation-inducing effect of piperitenone oxide, a fragrant ingredient of spearmint (Mentha spicata), but not carvone and menthol, against human colon cancer cells.Reviewed

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    Language：Japanese   Publishing type：Research paper (scientific journal)  

  • Tomoaki Shigeta, Yuichi Zaizen, Tadao Asami, Shigeo Yoshida, Yasushi Nakamura, Shigehisa Okamoto, Tomoaki Matsuo, Yasushi Sugimoto .  Molecular evidence of the involvement of heat shock protein 90 in brassinosteroid signaling in Arabidopsis T87 cultured cells .  Plant Cell Reports33   499 - 510   2014.1Molecular evidence of the involvement of heat shock protein 90 in brassinosteroid signaling in Arabidopsis T87 cultured cellsReviewed

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    Language：English   Publishing type：Research paper (scientific journal)  

  • Okamura T, Umemura T, Inoue T, Tasaki M, Ishii Y, Nakamura Y, Park EY, Sato K, Matsuo T, Okamoto S, Nishikawa A, Ogawa K .  Chemopreventive Effects of 4-Methylthio-3-butenyl Isothiocyanate (Raphasatin) but Not Curcumin against Pancreatic Carcinogenesis in Hamsters .  J. Agric. Food Chem.61 ( 9 ) 2103 - 2108   2013.2Chemopreventive Effects of 4-Methylthio-3-butenyl Isothiocyanate (Raphasatin) but Not Curcumin against Pancreatic Carcinogenesis in HamstersReviewed

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    Language：English   Publishing type：Research paper (scientific journal)  

  • Yuya Yoshimitsu, Kiwamu Tanaka, Wataru Fukuda, Tadao Asami, Shigeo Yoshida, Ken-ichiro Hayashi, Yuji Kamiya, Yusuke Jikumaru, Tomoaki Shigeta, Yasushi Nakamura, Tomoaki Matsuo, and Shigehisa Okamoto* .  Transcription of DWARF4 Plays a Crucial Role in Auxin-Regulated Root Elongation in Addition to Brassinosteroid Homeostasis in Arabidopsis thaliana .  PLoS ONE・www.plosone.org6 ( 8 ) e23851   2011.8Transcription of DWARF4 Plays a Crucial Role in Auxin-Regulated Root Elongation in Addition to Brassinosteroid Homeostasis in Arabidopsis thalianaReviewed

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    Language：English   Publishing type：Research paper (scientific journal)  

  • Tomoaki Shigeta, Daisuke Yasuda, Takafumi Mori, Yuya Yoshimitsu, Yasushi Nakamura,Shigeo Yoshida, Tadao Asami, Shigehisa Okamoto, Tomoaki Matsuo .  Characterization of brassinosteroid-regulated proteins in a nuclear-enrichedfraction of Arabidopsis suspension-cultured cells .  Plant Physiology and Biochemistry49   985 - 995   2011.5Characterization of brassinosteroid-regulated proteins in a nuclear-enrichedfraction of Arabidopsis suspension-cultured cellsReviewed

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    Language：English   Publishing type：Research paper (scientific journal)  

  • Yasushi Nakamura, Shinpei Watanabe, Minami Kageyama, Keiko Shirota, Koji Shirota,Hisashi Amano, Tadahiro Kashimoto, Tomoaki Matsuo, Shigehisa Okamoto,Eun Young Park, Kenji Sato .  Antimutagenic; differentiation-inducing; and antioxidative effects of fragrantingredients in Katsura-uri (Japanese pickling melon; Cucumis melo var. conomon) .  Mutation Research703   163 - 168   2010.12Antimutagenic; differentiation-inducing; and antioxidative effects of fragrantingredients in Katsura-uri (Japanese pickling melon; Cucumis melo var. conomon)Reviewed

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    Language：English   Publishing type：Research paper (scientific journal)  

  • Yoshimitsu Y., Tanaka K., Tagawa T., Nakamura Y., Matsuo T., Okamoto S. .  Improvement of DNA/Metal Particle Adsorption in Tungsten-Based Biolistic Bombardment; Alkaline pH is Necessary for DNA Adsorption and Suppression of DNA Degradation .  Journal of Plant Biology・Springer52   524 - 532   2009.9Improvement of DNA/Metal Particle Adsorption in Tungsten-Based Biolistic Bombardment; Alkaline pH is Necessary for DNA Adsorption and Suppression of DNA DegradationReviewed

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    Language：English   Publishing type：Research paper (scientific journal)  

  • Boonyaritthongchai P., Manuwong S., Kanlayanarat S., Nakamura Y., Okamoto S., Matsuo T. .  Acceleration of senescence by high temperature treatment in Lycoris (L. traubii x L. sanguinea) leaf sections. .  Journal of the Japanese Society for Horticultural Science 77   431 - 439   2008.10Acceleration of senescence by high temperature treatment in Lycoris (L. traubii x L. sanguinea) leaf sections.Reviewed

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  • Nakamura Y, Nakayama Y, Ando H, Tanaka A, Matsuo T, Okamoto S, Upham BL, Chang CC, Trosko JE, Park EY, Sato K. .  3-Methylthiopropionic Acid Ethyl Ester, Isolated from Katsura-uri (Japanese pickling melon, Cucumis melo var. conomon), Enhanced Differentiation in Human Colon Cancer Cells. .  J Agric Food Chem56 ( 9 ) 2977 - 2984   2008.53-Methylthiopropionic Acid Ethyl Ester, Isolated from Katsura-uri (Japanese pickling melon, Cucumis melo var. conomon), Enhanced Differentiation in Human Colon Cancer Cells.Reviewed

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    Language：English   Publishing type：Research paper (scientific journal)  

  • Nakamura Y., Nakamura K., Asai Y., Wada T., Tanaka K., Matsuo T., Okamoto S., Meijer J., Kitamura Y., Nishikawa A., Park E.Y., Sato K., and Ohtsuki K. .  Comparison of the glucosinolate-myrosinase systems among daikon (Raphanus sativus, Japanese white radish) varieties. .  J. Agric. Food Chem. 56 ( 8 ) 2702 - 2707   2008.4Comparison of the glucosinolate-myrosinase systems among daikon (Raphanus sativus, Japanese white radish) varieties. Reviewed

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    Language：English   Publishing type：Research paper (scientific journal)  

  • Yanohara T, Okamoto S, Hongye Z, Nakamura Y, and Matsuo T, .  Preparation of proteins from different organs of Japanese morning glory by an in vivo electro-elution procedure .  Phytochem. Anal., 16 ( 6 ) 397 - 404   2005.11Preparation of proteins from different organs of Japanese morning glory by an in vivo electro-elution procedureReviewed

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    Language：English   Publishing type：Research paper (scientific journal)  

  • Okamoto S., Tsuruda K., Yamaguchi N., Nakamura Y., and Matsuo T. .  Effects of reducing compounds on Agrobacterium-mediated transformation of sweet potato. .  Acta Horticulturae682 ( ※ ) 411 - 418   2005.6Effects of reducing compounds on Agrobacterium-mediated transformation of sweet potato.

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    Language：English   Publishing type：Research paper (other academic)  

  • Tanaka K., Asami T., Yoshida S., Nakamura Y., Matsuo T., and Okamoto S. .  Brassinosteroid homeostasis in Arabidopsis is ensured by feedback expressions of multiple genes involved in its metabolism. .  Plant Physiol.138 ( 2 ) 1117 - 1125   2005.5Brassinosteroid homeostasis in Arabidopsis is ensured by feedback expressions of multiple genes involved in its metabolism.Reviewed

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  • Okamoto S., Tanaka K., Tsuruyama K., Nakamura Y., and Matsuo T. .  Development and evaluation of a novel experimental system to control rosette leaf initiation in Arabidopsis. .  Plant Sci. 168 ( ※ ) 37 - 44   2005.1Development and evaluation of a novel experimental system to control rosette leaf initiation in Arabidopsis. Reviewed

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  • Kwamu Tanaka, Yasushi Nakamura, Tadao Asami, Shigeo Yoshida, Tomoaki Matsuo and Shigehisa Okamoto .  Physiological Roles of brassinosteroids in early growth of Arabidopsis: brassinosteroids have a synergistic relationship with gibberellin as well as auxin in light-grown hypocotyl elongation. .  JOURNAL OF PLANT GROWTH REGULATION22 ( 3 ) 259 - 271   2003.9Physiological Roles of brassinosteroids in early growth of Arabidopsis: brassinosteroids have a synergistic relationship with gibberellin as well as auxin in light-grown hypocotyl elongation.Reviewed

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    Language：English   Publishing type：Research paper (scientific journal)  

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MISC

  • Antimutagenic and Anticarcinogenic Properties of Kyo-yasai, Heirloom Vegetables in Kyoto Reviewed

    Yasushi Nakamura, Tomoaki Matsuo, Shigehisa Okamoto,Akiyoshi Nishikawa, Toshio Imai, Eun Young Park and Kenji Sato

    Genes and Environment 30(2), 41-47, 2008-05-20   30 ( 2 )   41 - 47   2008.5

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    Language：English   Publishing type：Article, review, commentary, editorial, etc. (scientific journal)  

  • ブラシノステロイド研究の進歩と農業利用への期待

    岡本繁久、田仲究、中村考志、松尾友明

    農業および園芸   82 ( 6 )   641 - 650   2007.6

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    Language：Japanese   Publishing type：Article, review, commentary, editorial, etc. (scientific journal)  

  • ブラシノステロイドの内生量を調節するしくみ

    岡本繁久、田仲究、松尾友明

    化学と生物   45 ( 1 )   34 - 42   2007.1

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    Language：Japanese   Publishing type：Article, review, commentary, editorial, etc. (scientific journal)  

Presentations

  • Yuya Yoshimitsu, Kiwamu Tanaka, Wataru Fukuda, Tadao Asami, Shigeo Yoshida, Ken-ichiro Hayashi, Yuji Kamiya, Yusuke Jikumaru, Tomoaki Shigeta, Yasushi Nakamura, Tomoaki Matsuo, Shigehisa Okamoto   Both auxin and brassinosteroids (BRs) conotrol the transcription of DWARF4 gene encording a BR biosynthesis enzyme   International conference

    21st International Conference on Arabidopsis Research Yokohama Japan  21st International Conference on Arabidopsis Research Yokohama Japan

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    Event date： 2010.6

    Language：English  

    Venue：横浜  

    国際学会

  • Okamoto S.,Yamaguchi N.,Tanaka K.,Nakamura Y.,Matsuo T.   Molecular and genetic characterization of a CENTRORALIADIS-Like gene,PnCEL from Japanese morning glory,Pharbitis nil choisy   International conference

    International Congress of Plant Molecular Biology  International Congress of Plant Molecular Biology

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    Event date： 2006.8

    Language：English  

    Venue：オーストラリア  

    国際学会

  • Okamoto S.,Tsuruda K.,Yamaguchi N.,Nakamura Y.,Matsuo T.   Effects of reducing compounds on agrobacterium-mediated transformation of sweet poteto   International conference

    International Postharvest Symposium  International Postharvest Symposium

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    Event date： 2004.6

    Language：English  

    Venue：イタリア  

    国際学会

  • Chucheep K.,Kanlayanarat S.,Nakamura Y.,Okamoto S.,Matsuo T.   Evaluation of chilling damage in tropical vegetables with three procedures   International conference

    5th International Postharvest Symposium  5th International Postharvest Symposium

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    Event date： 2004.6

    Language：English  

    Venue：イタリア  

    国際学会

  • Matsuo T.,SatoY.,Chucheep K.,Nakamura Y.,Okamoto S.   Chemical and biological characterization of proanthocyanidins with different MW profiles prepared from several fruits and leaves   International conference

    5th International Postharvest Symposium  5th International Postharvest Symposium

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    Event date： 2004.6

    Language：English  

    Venue：イタリア  

    国際学会

  • Kiwamu Tanaka, Yasushi Nakamura, Tadao Asami, Shigeo Yoshida, Tomoaki Matsuo, Shigehisa Okamoto   Brassinosteroid homeostasis is maintained by feedback control of expression of its metabolic genes   International conference

    The International Society for Plant Molecular Biology  The International Society for Plant Molecular Biology

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    Event date： 2003.6

    Language：English  

    Venue：スペイン  

    国際学会

  • Shigehisa Okamoto, Kiwamu Tanaka, Katsuya Tsuruyama, Yasushi Nakamura, Tomoaki Matsuo   Identification of Arabidopsis Genes Expressing in Shoot Apices During Rosette Leaf Development   International conference

    The International Society for Plant Molecular Biology  The International Society for Plant Molecular Biology

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    Event date： 2003.6

    Language：English  

    Venue：スペイン  

    国際学会

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Research Projects

  • A Relationship between Phytohormones and Symbiosis in Leguminous Plants

    2005

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  • マメ科植物の共生窒素固定に植物ホルモンが果たす役割

    2005

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    ミヤコグサの根粒形成、窒素固定過程におけるブラシノステロイドの働きを明らかにする。

  • Biosynthesis, Metabolism and Signaling of Brassinosteroids

    2000

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  • 植物ホルモン・ブラシノステロイドの作用機序

    2000

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    シグナル伝達依存的なブラシノステロイドの生合成・代謝の調節機構の解明。得られた知見の農業への利用。

  • Flowering Control in Pharbitis nil

    2000

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  • 植物由来の生理活性物質に関する研究

    1999

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    京都の伝統野菜が有する抗変異源性物質の単離と作用機序の解明

  • Bioactive Substance from Vegetables

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