Updated on 2021/04/23

写真a

 
HOU De-Xing
 
Organization
Research Field in Agriculture, Agriculture, Fisheries and Veterinary Medicine Area Faculty of Agriculture Department of Food Science and Biotechnology Professor
Research Field in Agriculture, Agriculture, Fisheries and Veterinary Medicine Area United Graduate School of Agricultural Sciences
Title
Professor

Degree

  • Doctor of Agriculture ( 1991.3   Kagoshima University )

  • Doctor of Pharmacoloy ( 2006.6   The University of Tokyo )

Research Interests

  • Functional Foods

  • Nutrigenomics

  • Phytochemicals

  • Gut microbiome. Food & Health

  • Metabolic syndrome

  • 食と健康

Research Areas

  • Life Science / Food sciences  / Food Function Science

  • Life Science / Pharmacology  / Pharmacological actions and molecular mechanisms of Natural compounds

  • Life Science / Applied molecular and cellular biology  / Cell signaling transduction, expression and regulation of genes

Education

  • Kagoshima University

    1986.4 - 1988.3

  • Kagoshima University

    1988.4 - 1991.3

Research History

  • Kagoshima University   Professor

    1997.11

  • Kagoshima University   Professor

    1997.11

Professional Memberships

  • 日本フードファクター学会

    2012.4

  • 日本農芸化学会

    2001.4

  • 日本食品科学工学学会

    2000.4

  • 日本栄養・食糧学会

    2000.4

  • 日本黒酢研究会

    2013.4

  • 日本栄養・食糧学会

    2001.10

  • 日本分子生物学会

    1993.4

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Committee Memberships

  • 日本フードファクター学会   理事  

    2012.4 - 2020.3   

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    Committee type:Other

    日本フードファクター学会

  • 日本食品科学工学会   評議員  

    2016.4 - 2018.3   

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    Committee type:Other

    日本食品科学工学会

  • 日本農芸化学会九州支部会   評議員  

    2012.4   

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    Committee type:Other

    日本農芸化学会九州支部会

  • 日本食糧栄養学会九州支部会   参与  

    2012.4   

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    日本食糧栄養学会九州支部会

  • 日本食品科学工学学会   九州支部副支部長  

    2020.4 - 2022.3   

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    Committee type:Academic society

  • 鹿児島県工業技術センター研究開発推進会議委員   委員  

    2014.4 - 2016.3   

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    Committee type:Other

    鹿児島県工業技術センター

  • 農林水産・食品産業科学技術研究推進事業シーズ創出ステージ   書面審査委員  

    2014.3 - 2014.4   

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    (公益社団)農林水産・食品産業技術振興会

  • 「機能性を持つ農林水産物・食品開発プロジェクト」における外部公募研究課題の外部審査員   外部審査員  

    2013.6   

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    一般財団法人 食品需給研究センター

  • 日本黒酢研究会   理事  

    2013.4   

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  • 健康長寿のまちづくり推進事業に係る戦略会議委員   委員  

    2012.11   

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    Committee type:Other

    南さつま市

  • 西日本機能性食品開発研究会実行委員会   委員  

    2012.4 - 2016.3   

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    西日本機能性食品開発研究会

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Studying abroad experiences

  • 2006.10 - 2007.3   Cornell Univ., Pittsuberg Univ., NIH-NCI  

 

Papers

  • De-Xing Hou, Hiroshi Akimaru, Shunsuke Ishii .  Trans-activation by the Drosophila myb gene product requires a Drosophila homologue of CBP .  FEBS Letters413 ( 1 ) 60 - 64   1997.8Trans-activation by the Drosophila myb gene product requires a Drosophila homologue of CBPReviewed

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  • Hiroshi Akimaru, De-Xing Hou, Shunsuke Ishii .  Drosophila CBP is required for dorsal-dependent twist gene expression .  Nature Genetics17 ( 2 ) 211 - 214   1997.10Drosophila CBP is required for dorsal-dependent twist gene expressionReviewed

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  • De-Xing Hou*, Keiko Kai, Jian-Jian Li, Shigang Lin, Norihiko Terahara, Mika Wakamatsu, Makoto Fujii, Mattew R. Young, Nancy Colburn .  Anthocyanidins inhibit activator protein-1 activity and cell transformation: structure-Activity relationship and molecular mechanisms .  Carcinogenesis25 ( 1 ) 29 - 36   2004.1Anthocyanidins inhibit activator protein-1 activity and cell transformation: structure-Activity relationship and molecular mechanismsReviewed

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  • De-Xing Hou*, Takashi Yanagita, Takuhiro Uto, Satoko Masuzaki, Makoto Fujii .  Anthocyanidins inhibit cyclooxygenase-2 expression in LPS-evoked macrophages: Structure-activity relationship and molecular mechanisms involved. .  Biochemical Pharmacology70 ( 3 ) 417 - 425   2005.8Anthocyanidins inhibit cyclooxygenase-2 expression in LPS-evoked macrophages: Structure-activity relationship and molecular mechanisms involved.Reviewed

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  • De-Xing Hou*, Dong Luo, Shunsuke Tanigawa,Fumio Hashimoto, Takuhiro Uto, Satoko Masuzaki, Makoto Fujii, Yusuke Sakata. .  Prodelphinidin B-4 3’-O-gallate, a tea polyphenol, is involved in the inhibition of COX-2 and iNOS via the downregulation of TAK1-NF-kB pathway .  Biochemical Pharmacology74 ( 5 ) 742 - 751   2007.9Prodelphinidin B-4 3’-O-gallate, a tea polyphenol, is involved in the inhibition of COX-2 and iNOS via the downregulation of TAK1-NF-kB pathwayReviewed

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  • Shunsuke Tanigawa, Makoto Fujii, De-Xing Hou* .  Action of Nrf2 and Keap1 in ARE-mediated NQO1 expression by quercetin .  Free Radical Biology and Medicine42 ( 11 ) 1690 - 1703   2007.6Action of Nrf2 and Keap1 in ARE-mediated NQO1 expression by quercetinReviewed

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  • Tanigawa S, Lee CH, Lin CS, Ku CC, Hasegawa H, Qin S, Kawahara A, Korenori Y, Miyamori K, Noguchi M, Lee LH, Lin YC, Steve Lin CL, Nakamura Y, Jin C, Yamaguchi N, Eckner R, Hou DX*, Yokoyama KK .  Jun dimerization protein 2 is a critical component ofthe Nrf2/MafK complex regulating the response to ROS homeostasis .  Cell Death Dis. 4 ( e921 )   2013.12Jun dimerization protein 2 is a critical component ofthe Nrf2/MafK complex regulating the response to ROS homeostasisReviewed

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  • Hou DX*, Korenori Y, Tanigawa S, Yamada-Kato T, Nagai M, He X and He JH .  Dynamics of Nrf2 and Keap1 in ARE-mediated NQO1 expression by Wasabi 6-(methylsulfinyl)hexyl isothiocyanate .  J Agric Food Chem59 ( 22 ) 11975 - 11982   2011.12Dynamics of Nrf2 and Keap1 in ARE-mediated NQO1 expression by Wasabi 6-(methylsulfinyl)hexyl isothiocyanateReviewed

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  • Ameliorative effects and molecular mechanisms of vine tea on Western diet-induced NAFLD .  Food and Function11 ( 7 ) 5976 - 5991   2020.8Ameliorative effects and molecular mechanisms of vine tea on Western diet-induced NAFLDReviewed

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  • Wu S, Yano S, Hisanaga A, He X, He J, Sakao K, Hou DX* .  Polyphenols from Lonicera caerulea L. berry attenuate experimental nonalcoholic steatohepatitis by inhibiting proinflammatory cytokines productions and lipid peroxidation .  Mol Nutr Food Res.61 ( 4 )   2017.4Polyphenols from Lonicera caerulea L. berry attenuate experimental nonalcoholic steatohepatitis by inhibiting proinflammatory cytokines productions and lipid peroxidationInvited Reviewed

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  • Qin S, Hou DX* .  Multiple regulations of Keap1/Nrf2 system by dietary phytochemicals .  Mol. Nutr. Food Res60   1731- - 1755   2016.7Multiple regulations of Keap1/Nrf2 system by dietary phytochemicalsReviewed

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  • You S, Nakanishi E, Kuwata H, Chen J, Nakasone Y, He X, He J, Liu X, Zhang S, Zhang B, Hou DX*. .  Inhibitory effects and molecular mechanisms of garlic organosulfur compounds on the production of inflammatory mediators .  Mol Nutr Food Res57 ( 11 ) 2049 - 2060   2013.11Inhibitory effects and molecular mechanisms of garlic organosulfur compounds on the production of inflammatory mediatorsReviewed

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  • Hou DX*, Masuzaki S, Tanigawa S,Hashimoto F, Chen J, Sogo T,Fujii M. .  Oolong tea theasinensins attenuate cyclooxygenase-2 expression in lipopolysaccharide (LPS)-activated mouse macrophages: Structure-activity relationship and molecular mechanisms .  J. Agri. Food Chem.58   12735 - 12743   2010.11Oolong tea theasinensins attenuate cyclooxygenase-2 expression in lipopolysaccharide (LPS)-activated mouse macrophages: Structure-activity relationship and molecular mechanismsReviewed

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  • Masahiro Okada, Hiroshi Akimaru, De-Xing Hou, Tomomi Takahashi, Shunsuke Ishii .  Myb controls G2/M progression by inducing cyclin B expression in the Drosophila eye imaginal disc .  The EMBO Journal21 ( 4 ) 675 - 684   2002.4Myb controls G2/M progression by inducing cyclin B expression in the Drosophila eye imaginal discReviewed

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  • Hiroshi Akimaru, Y Chen, Ping Dai, De-Xing Hou, M Nonaka, SM Smolik, S Armstrong, RH Goodman, Shunsuke Ishii .  Drosophila CBP is a co-activator of cubitus interruptus in hedgehog signalling .  Nature386 ( 6626 ) 735 - 738   1997.4Drosophila CBP is a co-activator of cubitus interruptus in hedgehog signallingReviewed

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  • Isao Okunishi, Yousuke Miura, Yo Nakamura,, Yoshitada Hira, De-Xing Hou .  Isao Okunishi, Yousuke Miura, Yo Nakamura,, Yoshitada Hira, De-Xing Hou: Assessment of mutagenicity, acute and sub-acute toxicity and human trial safety of wasabi leaf extract powder .  Food Science and Technology Research   2021.1Isao Okunishi, Yousuke Miura, Yo Nakamura,, Yoshitada Hira, De-Xing Hou: Assessment of mutagenicity, acute and sub-acute toxicity and human trial safety of wasabi leaf extract powderReviewed

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  • Hironobu Nakano, Shusong Wu, Kozue Sakao, Taichi Hara, Jianhua He, Santos Garcia, Kalidas Shetty and De-Xing Hou .  Bilberry Anthocyanins Ameliorate NAFLD by Improving Dyslipidemia and Gut Microbiome Dysbiosis. .  Nutrients   2020.10Bilberry Anthocyanins Ameliorate NAFLD by Improving Dyslipidemia and Gut Microbiome Dysbiosis.Invited Reviewed

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  • Isao Okunishi, Tomoe Yamada-Kato, Jiro Saito, De-Xing Hou .  Isao Okunishi, Tomoe Yamada-Kato, Jiro Saito, De-Xing Hou: Safety evaluation of 6-(methylsulfinyl) hexyl isothiocyanate (6-MSITC) and Wasabi sulfinyl, a 6-MSITC containing supplement. .  Food Science and Technology Research.   2020.10Isao Okunishi, Tomoe Yamada-Kato, Jiro Saito, De-Xing Hou: Safety evaluation of 6-(methylsulfinyl) hexyl isothiocyanate (6-MSITC) and Wasabi sulfinyl, a 6-MSITC containing supplement.Reviewed

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  • Ruizhi Hu, Ziyu He, Ming Liu, Jijun Tan, Hongfu Zhang, De-Xing Hou, Jianhua He1and Shusong Wu .  Dietary protocatechuic acid ameliorates inflammation and up-regulates intestinal tight junction proteins by modulating gut microbiota in LPS-challenged piglets. .  Journal of Animal Science and Biotechnology   2020.9Dietary protocatechuic acid ameliorates inflammation and up-regulates intestinal tight junction proteins by modulating gut microbiota in LPS-challenged piglets. Reviewed

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  • Xupeng Yuan, Jiahao Yan, Ruizhi Hu, Yanli Li, Ying Wang, Hui Chen, De-Xing Hou, Jianhua He, Shusong Wu .  Modulation of Gut Microbiota and Oxidative Status by β-Carotene in Late Pregnant Sows .  Front in Nutrition14 ( 7 )   2020.7Modulation of Gut Microbiota and Oxidative Status by β-Carotene in Late Pregnant SowsInternational coauthorship

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    DOI: 10.3389/fnut.2020.61

  • Zhu-Ying Liu, Xiao-Long Wang, Shu-Qi Ou, De-Xing Hou, Jian-Hua He .  Sanguinarine modulate gut microbiome and intestinal morphology to enhance growth performance in broilers. .  PLOS ONE   2020.6Sanguinarine modulate gut microbiome and intestinal morphology to enhance growth performance in broilers. Reviewed

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  • Chen K, Nakasone Y, Xie K, Sakao K, Hou DX .  Modulation of Allicin-Free Garlic on Gut Microbiome .  Molecules   2020.2Modulation of Allicin-Free Garlic on Gut MicrobiomeReviewed

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  • Li R, Hou G, Jiang X, Song Z, Fan Z, Hou DX, He X .  Different dietary protein sources in low protein diets regulate colonic microbiota and barrier function in a piglet model .  Food and Function   2019.10Different dietary protein sources in low protein diets regulate colonic microbiota and barrier function in a piglet modelInvited Reviewed

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  • Xie K, He X, Chen K, Chen J, Sakao K, Hou DX .  Antioxidant Properties of a Traditional Vine Tea, Ampelopsis grossedentata .  Antioxidants (Basel)   2019.8Antioxidant Properties of a Traditional Vine Tea, Ampelopsis grossedentataInvited Reviewed

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  • Chen J, Li Y, Liu F, Hou DX, Xu J, Zhao X, Yang F, Feng X .  Prodigiosin Promotes Nrf2 Activation to Inhibit Oxidative Stress Induced by Microcystin-LR in HepG2 Cells .  Toxins (Basel)   2019.7Prodigiosin Promotes Nrf2 Activation to Inhibit Oxidative Stress Induced by Microcystin-LR in HepG2 CellsReviewed

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  • Li R, Chang L, Hou G, Song Z, Fan Z, He X, Hou DX .  Colonic Microbiota and Metabolites Response to Different Dietary Protein Sources in a Piglet Model .  Frontiers in Nutrition   2019.6Colonic Microbiota and Metabolites Response to Different Dietary Protein Sources in a Piglet ModelReviewed

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  • Chen K, Xie K, Liu Z, Nakasone Y, Sakao K, Hossain A, Hou DX .  Preventive Effects and Mechanisms of Garlic on Dyslipidemia and Gut Microbiome Dysbiosis .  Nutrients   2019.5Preventive Effects and Mechanisms of Garlic on Dyslipidemia and Gut Microbiome DysbiosisInvited Reviewed

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  • Li R, Hou G, Song Z, Wu C, Zhao X, Xiang X. Fan Z, Hou DX, He X .  Effects of different protein sources completely replacing fishmeal in low protein diet on growth performance, intestinal digestive physiology, and nitrogen digestion and metabolism in nursery pigs .  Japanese Society of Animal Science   2019.5Effects of different protein sources completely replacing fishmeal in low protein diet on growth performance, intestinal digestive physiology, and nitrogen digestion and metabolism in nursery pigsReviewed

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  • Yano S, Wu S, Sakao K, Hou DX .  Involvement of ERK1/2-mediated ELK1/CHOP/DR5 pathway in 6-(methylsulfinyl)hexyl isothiocyanate-induced apoptosis of colorectal cancer cells .  Biosci Biotechnol Biochem   2019.5Involvement of ERK1/2-mediated ELK1/CHOP/DR5 pathway in 6-(methylsulfinyl)hexyl isothiocyanate-induced apoptosis of colorectal cancer cellsReviewed

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  • Kinjo Y, Takahashi M, Hirose N, Mizu M, Hou DX, Wada K .  Anti-stress and Antioxidant Effects of Non Centrifuged Cane Sugar, Kokuto, in Restraint-Stressed Mice .  Journal of Oleo Science   2019.2Anti-stress and Antioxidant Effects of Non Centrifuged Cane Sugar, Kokuto, in Restraint-Stressed MiceReviewed

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  • Li T, Li Q, Wu W, Li Y, Hou DX, Xu H, Zheng B, Zeng S, Shan Y, Lu X, Deng F, Qin S .  Lotus seed skin proanthocyanidin extract exhibits potent antioxidant property via activation of the Nrf2-ARE pathway .  Acta Biochimica et Biophysicca Sinica (Shanghai)   2019.1Lotus seed skin proanthocyanidin extract exhibits potent antioxidant property via activation of the Nrf2-ARE pathwayReviewed

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  • Zhang H, Zheng W, Feng X, Yang F, Qin H, Wu S, Hou DX, Chen J .  Nrf2-ARE Signaling Acts as Master Pathway for the Cellular Antioxidant Activity of Fisetin .  Molecules   2019Nrf2-ARE Signaling Acts as Master Pathway for the Cellular Antioxidant Activity of FisetinReviewed

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  • 章超, 村上愛, 坂尾こず枝, 久永絢美, 河野邦晃, 岩井謙一, 髙瀬良和, 侯德興 .  サツマイモ焼酎チャーガスピリッツの抗炎症機能の解析 .  日本醸造協会誌   2018.12サツマイモ焼酎チャーガスピリッツの抗炎症機能の解析Reviewed

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  • Liu Z, Wang X, Ou S, Arowolo MA, Hou DX, He J .  Effects of Achyranthes bidentata Polysaccharides on Intestinal Morphology, Immune Response, and Gut Microbiome in Yellow Broiler Chickens Challenged with Escherichia coli K88 .  Polymers (Basel)   2018.12Effects of Achyranthes bidentata Polysaccharides on Intestinal Morphology, Immune Response, and Gut Microbiome in Yellow Broiler Chickens Challenged with Escherichia coli K88Invited Reviewed

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  • Wu S, Hu R, Nakano H, Chen K, Liu M, He X, Zhang H, He J, Hou DX .  Modulation of Gut Microbiota by Lonicera caerulea L. Berry Polyphenols in a Mouse Model of Fatty Liver Induced by High Fat Diet .  Molecules   2018.12Modulation of Gut Microbiota by Lonicera caerulea L. Berry Polyphenols in a Mouse Model of Fatty Liver Induced by High Fat DietInvited Reviewed

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  • Jesmin Akter, Md. Zahorul Islam, Md. Amzad Hossain, Shinsuke Kawabata, Kensaku Takara, Ha Thi Thanh Nguyen, De-Xing Hou .  Endothelium- independent and calcium channel-dependent relaxation of the porcine cerebral artery by different species and strains of turmeric .  Journal of Traditional and Complementary Medicine   2018.5Endothelium- independent and calcium channel-dependent relaxation of the porcine cerebral artery by different species and strains of turmericReviewed

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  • Yano S, Wu SS, Sakao K, Hou DX .  Wasabi 6-MSITC induces apoptosis in human colorectal cancer cells through p53-independent mitochondrial dysfunction pathway .  BioFactors   2018.4Wasabi 6-MSITC induces apoptosis in human colorectal cancer cells through p53-independent mitochondrial dysfunction pathwayReviewed

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  • Jesmin Akter, Md. Amzad Hossain, Ayako Sano, Kensaku Takara, Md. Zahorul Islam, and De-Xing Hou .  Antifungal activity of various species and strains of turmeric (Curcuma spp.) against Fusarium solani sensu lato .  Pharmaceutical Chemistry Journal   2018.4Antifungal activity of various species and strains of turmeric (Curcuma spp.) against Fusarium solani sensu latoReviewed

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  • Jesmin Akter, Md. Zahorul Islam, Kensaku Takara, Md. Amzad Hossain, Shinichi Gima and De-Xing Hou .  Plant growth inhibitors in turmeric (Curcuma longa) and their effects on Bidens pilosa .  Weed Biology and Management.   2018.3 Plant growth inhibitors in turmeric (Curcuma longa) and their effects on Bidens pilosaReviewed

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  • Li R, Song Z, Zhao J, Huo D, Fan Z, Hou DX, He X .  Dietary L-theanine alleviated lipopolysaccharide-induced immunological stress in yellow-feathered broilers .  Anim Nutr.   2018.3Dietary L-theanine alleviated lipopolysaccharide-induced immunological stress in yellow-feathered broilersInvited Reviewed

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  • Liu M, Tan J, He Z, He X, Hou DX, He J, Wu S .  Inhibitory effect of blue honeysuckle extract on high-fat-diet-induced fatty liver in mice .  Anim Nutr.   2018.3Inhibitory effect of blue honeysuckle extract on high-fat-diet-induced fatty liver in miceReviewed

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  • esmin Akter, Md. Amzad Hossain, Kensaku Takara, Md. Zahorul Islam, De-Xing Hou .  Antioxidant activity of different species and varieties of turmeric (Curcuma spp): Isolation of active compounds .  Comparative Biochemistry and Physiology, Part C   2018Antioxidant activity of different species and varieties of turmeric (Curcuma spp): Isolation of active compoundsReviewed

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  • Wu S, Yano S, Jihua Chen, Hisanaga A, Sakao K, He X, He J, Hou DX* .  Polyphenols from Lonicera caerulea L. Berry Inhibit LPS-induced Inflammation through Dual Modulation of Inflammatory and Antioxidant Mediators .  J. Agric. Food Chem. 65 ( 25 ) 5133 - 5141   2017.6Polyphenols from Lonicera caerulea L. Berry Inhibit LPS-induced Inflammation through Dual Modulation of Inflammatory and Antioxidant MediatorsReviewed

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  • Qian Lin, Jianfei Zhao, Kun Xie, Yushi Wang, Guili Hu, Guitao Jiang, Qiuzhong Dai , Zhiyong Fan, Jianhua He, Xi He, De-Xing Hou* .  Magnolol additive as a replacer of antibiotic enhances the growth performance of Linwu ducks. .  Animal Nutrition   2017.3Magnolol additive as a replacer of antibiotic enhances the growth performance of Linwu ducks.Reviewed

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  • Takahara M, Kinjo Y, Uechi S, Hirose N, Mizu M, Hou DX, Wada K .  Effects of oral intake of noncentrifugal cane brown sugar, Kokuto, on mental stress in humans .  J Japan Assoc. Food Preservation Science43 ( 3 ) 123 - 132   2017.3Effects of oral intake of noncentrifugal cane brown sugar, Kokuto, on mental stress in humansReviewed

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  • Trio PZ, Kawahara A, Tanigawa S, Sakao K, Hou DX* .  DNA microarray profiling highlights Nrf2-mediated chemoprevention targeted by wasabi-derived isothiocyanates in HepG2 cells .  Nutr Cancer69 ( 1 ) 105 - 116   2017.2DNA microarray profiling highlights Nrf2-mediated chemoprevention targeted by wasabi-derived isothiocyanates in HepG2 cellsReviewed

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  • Mukai R, Matsui N, Fujikura Y, Matsumoto N, Hou DX, Kanzaki N, Shibata H, Horikawa M, Iwasa K, Hirasaka K, Nikawa T, Terao J .  Preventive effect of dietary quercetin on disuse muscle atrophy by targeting mitochondria in denervated mice .  J Nutr Biochem. 31   67 - 76   2016.5Preventive effect of dietary quercetin on disuse muscle atrophy by targeting mitochondria in denervated miceReviewed

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  • Hisanaga A, Mukai R, Sakao K, Terao J, Hou DX. .  Anti-inflammatory effects and molecular mechanisms of 8-prenyl quercetin .  Mol Nutr Food Res.60 ( 5 ) 1020 - 1032   2016.5Anti-inflammatory effects and molecular mechanisms of 8-prenyl quercetinReviewed

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  • Nguyen HT, Nguyen HT, Islam MZ, Obi T, Pothinuch P, Zar PP, Hou DX, Van Nguyen T, Nguyen TM, Van Dao C, Shiraishi M, Miyamoto A .  Pharmacological characteristics of Artemisia vulgaris L. in isolated porcine basilar artery .  J Ethnopharmacol. 182   16 - 26   2016.3Pharmacological characteristics of Artemisia vulgaris L. in isolated porcine basilar arteryReviewed

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  • Wu SS, He X, Wu XS, Qin S, He JH, Zhang SR, Hou DX* .  Inhibitory effects of blue honeysuckle (Loniceracaerulea L) on adjuvant-induced arthritis in rats: Crosstalk of anti-inflammatory and antioxidant effects .  Journal of Functional Foods17   514 - 523   2015.5 Inhibitory effects of blue honeysuckle (Loniceracaerulea L) on adjuvant-induced arthritis in rats: Crosstalk of anti-inflammatory and antioxidant effectsReviewed

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  • Sogo T, Terahara N, Hisanaga A, Kumamoto T, Yamashiro T, Wu S, Sakao K, Hou DX* .  Anti-inflammatory activity and molecular mechanism of delphinidin 3-sambubioside, a Hibiscus anthocyanin .  Biofactors41 ( 1 ) 58 - 65   2015.1Anti-inflammatory activity and molecular mechanism of delphinidin 3-sambubioside, a Hibiscus anthocyaninReviewed

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  • Sogo T, Kumamoto T, Ishida H, Hisanaga A, Sakao K, Terahara N, Wada K, Hou DX* .  Comparison of the Inhibitory Effects of Delphinidin and Its Glycosides on Cell Transformation .  Planta Medica 81 ( 1 ) 26 - 31   2015.1Comparison of the Inhibitory Effects of Delphinidin and Its Glycosides on Cell TransformationReviewed

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  • Abe N, Hou DX, Munemasa S, Murata Y, Nakamura Y .  Nuclear factor-kappaB sensitizes to benzyl isothiocyanate-induced antiproliferation in p53-deficient colorectal cancer cells .  Cell Death Dis.5 ( e1534 )   2014.12Nuclear factor-kappaB sensitizes to benzyl isothiocyanate-induced antiproliferation in p53-deficient colorectal cancer cellsReviewed

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  • Hisanaga A, Ishida H, Sakao K, Sogo T, Kumamoto T, Hashimoto F and Hou DX .  Anti-inflammatory activity and molecular mechanism of Oolong tea theasinensin. .  Food & Function5 ( 8 ) 1891 - 1897   2014.8Anti-inflammatory activity and molecular mechanism of Oolong tea theasinensin.Reviewed

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  • Zar PPK, Morishita A, Hashimoto F, Sakao K, Fujii M, Wada K, Hou DX .  Anti-inflammatory effects and molecularmechanisms of loquat (Eriobotrya japonica) tea .  J Funct Food6   523 - 533   2014.1Anti-inflammatory effects and molecularmechanisms of loquat (Eriobotrya japonica) teaReviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

  • Korenori Y, Tanigawa S, Kumamoto T, Qin S, Miyamori K, Nagai M and Hou DX .  Modulation of Nrf2/Keap1 System by Wasabi 6-Methylthiohexyl Isothiocyanate in ARE-mediated NQO1 Expression .  Mol Nutr Food Res57 ( 4 ) 854 - 864   2013.4Modulation of Nrf2/Keap1 System by Wasabi 6-Methylthiohexyl Isothiocyanate in ARE-mediated NQO1 ExpressionReviewed

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  • Qin S, Chen J, Tanigawa S and Hou DX .  Microarray and pathway analysis highlight Nrf2/ARE-mediated expression profiling by polyphenolic myricetin .  Mol Nutr Food Res57 ( 3 ) 435 - 446   2013.3Microarray and pathway analysis highlight Nrf2/ARE-mediated expression profiling by polyphenolic myricetinReviewed

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  • Kumamoto T, Fujii M, Hou DX*. .  Akt is a direct target for myricetin to inhibit cell transformation. .  Molecular and Cellular Biochemistry332 ( 42006 ) 33 - 41   2009.12Akt is a direct target for myricetin to inhibit cell transformation.Reviewed

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  • De-Xing Hou*, Satoko Masuzaki, Fumio Hashimoto, Takuhiro Uto, Shunsuke Tanigawa, Makoto Fujii, Yusuke Sakata .  Green tea proanthocyanidins inhibit cyclooxygenase-2 expression in LPS-activated mouse macrophages: molecular mechanisms and structure-activity relationship. .  Archives of Biochemistry and Biophysics460 ( 1 ) 67 - 74   2007.4Green tea proanthocyanidins inhibit cyclooxygenase-2 expression in LPS-activated mouse macrophages: molecular mechanisms and structure-activity relationship.Reviewed

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  • De-Xing Hou*, Xuhui Tong, Norihiko Terahara, Dong Luo, Makoto Fujii .  Delphinidin 3-sambubioside, a Hibiscus anthocyanin, induces apoptosis in human leukemia cells through reactive oxygen species-mediated mitochondrial pathway .  Archives of Biochemistry and Biophysics440 ( 1 ) 101 - 109   2005.8Delphinidin 3-sambubioside, a Hibiscus anthocyanin, induces apoptosis in human leukemia cells through reactive oxygen species-mediated mitochondrial pathwayReviewed

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  • Xuhui Tong, Shigang Lin, Makoto Fujii, De-Xing Hou* .  Molecular mechanisms of echinocystic acid-induced apoptosis in HepG2 cells .  Biochemical and Biophysical Research Communications321 ( 3 ) 539 - 546   2004.8Molecular mechanisms of echinocystic acid-induced apoptosis in HepG2 cellsReviewed

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  • De-Xing Hou*, Takuhiro Uto, Xuhui Tong, Takeshi Takeshita, Izumi Imamura, Takeshi Ose, Makoto Fujii .  Involvement of reactive oxygen species-independent mitochondrial pathway in gossypol-induced apoptosis .  Archives of Biochemistry and Biophysics428 ( 2 ) 179 - 187   2004.8Involvement of reactive oxygen species-independent mitochondrial pathway in gossypol-induced apoptosisReviewed

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  • De-Xing Hou*, Takeshi Ose, Shigang Lin, Kazuhiro Harazono, Izumi Imamura, Mayumi Kubo, Takuhiro Uto, Norihiko Terahara, Makoto Yoshimoto, Makoto Fujii .  Anthocyanidins induce apoptosis in human promyelocytic leukemia cells: Structure-activity relationship and mechanisms involved .  International Journal of Oncology23 ( 3 ) 705 - 712   2003.9Anthocyanidins induce apoptosis in human promyelocytic leukemia cells: Structure-activity relationship and mechanisms involvedReviewed

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  • De-Xing Hou*, Masahiro Fukuda, Makoto Fujii, Yoko Fuke .  Transcriptional regulation of nicotinamide adenine dinucleotide phosphate: quinone oxidoreductase in murine hepatoma cells by 6-(methylsufinyl) hexyl isothiocyanate, an active principle of wasabi (#IEutrema Wasabi Maxim#I.) .  Cancer Letters161 ( 2 ) 195 - 200   2000.12Transcriptional regulation of nicotinamide adenine dinucleotide phosphate: quinone oxidoreductase in murine hepatoma cells by 6-(methylsufinyl) hexyl isothiocyanate, an active principle of wasabi (#IEutrema Wasabi Maxim#I.)Reviewed

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  • Ping Dai, Hiroshi Akimaru, Yasunori Tanaka, De-Xing Hou, Takashi Yasukawa,Chie Kanei-Ishii, Tomomi Takahashi, Shunsuke Ishii .  CBP as a transcriptional coactivator of c-Myb .  Genes and Development10 ( 5 ) 528 - 540   1996.3CBP as a transcriptional coactivator of c-MybReviewed

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  • Eiichi Soeda, De-Xing Hou, Kazutoyo Osoegawa, Yasuo Atsuchi, Tetsushi Yamagata, Takanori Shimogawa, Haruo Kishida, Eiichi Soeda, Ssaishi Okano, Ilya Chumakov .  Cosmid assembly and anchoring to human chromosome 21 .  Genomics25 ( 1 ) 73 - 84   1995.1Cosmid assembly and anchoring to human chromosome 21Reviewed

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  • De-Xing Hou, Yoshizane Maeda, Shin Okamoto, Tsutomu Hashiguchi .  Structural difference of chymotrypsinogens forming chymotrypsin variants in Japanese quail. .  Biochemical Genetics28 ( 11月12日 ) 571 - 576   1990.12Structural difference of chymotrypsinogens forming chymotrypsin variants in Japanese quail.Reviewed

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  • De-Xing Hou, Yoshizane Maeda, Shin Okamoto, Tsutomu Hashiguchi .  Purification and characterization of chymotrypsinogen from pancreas of Japanese quail (Coturnix coturnix japonica). .  Comparative Biochemistry and Physiology B97 ( 4 ) 761 - 766   1990.4Purification and characterization of chymotrypsinogen from pancreas of Japanese quail (Coturnix coturnix japonica).Reviewed

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  • De-Xing Hou, Yoshizane Maeda, Shin Okamoto, Tsutomu Hashiguchi .  Genetic studies on pancreatic proteinase in Japanese quail. .  Biochemical Genetics27 ( 7月8日 ) 469 - 479   1989.8Genetic studies on pancreatic proteinase in Japanese quail.Reviewed

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Books

  • Functional Foods and Biotechnology: Biotransformation and Analysis of Functional Foods and Ingredients

    Si Qin, Chenghao LV, De-Xing Hou( Role: Joint author)

    CRC Press  2020.5 

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    Responsible for pages:295-326   Language:English Book type:Scholarly book

  • Asian Berries: Health Benefits

    Shusong Wu, De-Xing Hou( Role: Joint author)

    CRC Press  2020.11 

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    Responsible for pages:327-342   Language:English Book type:Scholarly book

  • 非栄養素の分子栄養学

    侯 德興( Role: Joint author)

    建帛社出版  2017.5 

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    Language:Japanese Book type:Scholarly book

  • 鹿児島の食環境と健康食材

    侯 德興、中野隆之、橋本文雄、藤井 信( Role: Joint author)

    南方新聞出版  2016.3 

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    Language:Japanese Book type:General book, introductory book for general audience

  • Molecular Basis for Cancer Chemopreventive Effects of Anthocyans

    Hou DX( Role: Sole author)

    Lambert Academic Publishing, Germany. ISBN: 978-3-659-15016-6   2012.8 

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    Language:English Book type:Scholarly book

  • アントシアニンとがん予防

    侯 徳興( Role: Sole author)

    アントシアニンの科学 -生理機能・製品開発も新展開 -(建帛社)  2009.4 

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    Language:Japanese Book type:Scholarly book

  • Cancer-Preventive Effects and Molecular Actions of Anthocyanins

    De-Xing Hou( Role: Sole author)

    NUTRIGENOMICS AND PROTEOMICS IN HEALTH AND DISEASE - Food Factors and Gene Interactions (WILEY-BLACKWELL)  2009.1 

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    Language:English Book type:Scholarly book

  • Anthocyans and Chemoprevention: Evidence from Cellular Investigations.

    De-Xing Hou* ( Role: Joint author)

    Functional Food and Health. American Chemistry Society Press.  2008.12 

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    Language:English Book type:Scholarly book

  • 植物色素研究法

    侯 徳興( Role: Sole author)

    大阪公立大学共同出版会発行  2004.3 

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    Language:Japanese Book type:Scholarly book

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MISC

  • The Effects and Mechanisms of Cyanidin-3-Glucoside and Its Phenolic Metabolites in Maintaining Intestinal Integrity Reviewed

    Tan J, Li Y, Hou DX, Wu S

    Antioxidants (Basel)   2019.10

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    Language:English   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

  • The Biofunctions of Phytochemicals and Their Applications in Farm Animals: The Nrf2/Keap1 System as a Target Reviewed

    Qin S, Hou DX*

    Engineering   2017.12

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    Language:English   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

  • ポリフェノールの機能発現に関わる分子標的 Reviewed

    隈元拓馬、久永絢美、侯 徳興*

    オレオサイエンス   17 ( 10 )   497 - 504   2017.10

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

  • Multiple regulations of Keap1/Nrf2 system by dietary phytochemicals

    Si Qin, De-Xing Hou

    Mol. Nutr. Food Res.   60   1731 - 1755   2016.6

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (bulletin of university, research institution)  

  • アントシアニンのがん予防機能について Reviewed

    侯 徳興

    Functional Food   8 ( 2 )   93 - 98   2014.9

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  • 果実・果汁飲料と機能性成分(20):ビワ茶の健康維持機能 Reviewed

    侯 徳興

    食品と容器   55 ( 8 )   476 - 481   2014.7

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

  • Chemopreventive functions and molecular mechanisms of garlic organosulfur compounds. Reviewed

    Trio PZ, You S, He X, He J, Sakao K, Hou DX.

    Food Funct.   5 ( 5 )   833 - 844   2014.4

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  • Flavonoids as protein kinase inhibitors for cancer chemoprevention: direct binding and molecular modeling Reviewed

    Hou DX*, Kumamoto T.

    Antioxidants and Redox Signaling   13 ( 5 )   691 - 719   2010.9

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  • Molecular mechanisms behind the chemopreventive effects of anthocyanidins (Review) Reviewed

    De-Xing Hou*, Makoto Fujii, Norihiko Terahara, Makoto Yoshimoto

    Journal of Biomedicine and Biotechnology   4 ( 5 )   321 - 325   2004.10

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  • Potential mechanisms of cancer chemoprevention by anthocyanins (Review) Reviewed

    De-Xing Hou*

    Current Molecular Medicine   3 ( 2 )   149 - 159   2003.3

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Presentations

  • 山下智代、坂尾こず枝、賀喜、侯德興   脂質代謝および腸内細菌叢におけるローズマリーの影響に関する研究   International conference

    日本栄養・食糧学会九州・沖縄支部大会 (オンライン開催) 

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    Event date: 2020.11

    Language:Japanese   Presentation type:Oral presentation (general)  

  • De-Xing Hou   Innovation of local food resources for human health: From lab bench studies to healthy table   Invited International conference

    Online International Symposium of FSMILE 2020-Current Trends on Food Processing, Safety and Nutrition. 

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    Event date: 2020.11

    Language:English   Presentation type:Oral presentation (invited, special)  

  • Keyu Chen, Kozue Sakao, De-Xing Hou   Garlic as potential prebiotics to prevent gut microbiota dysbiosis and dyslipidemia   International conference

    Online International Symposium of FSMILE 2020-Current Trends on Food Processing, Safety and Nutrition. 

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    Event date: 2020.11

    Language:English   Presentation type:Oral presentation (general)  

  • Keyu Chen, Kozue Sakao, De-Xing Hou   Preventive Effects and Mechanisms of Garlic on Dyslipidemia and Gut Microbiome Dysbiosis  

    日本農芸化学会2020大会 

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    Event date: 2020.3

    Language:English   Presentation type:Poster presentation  

  • Kun Xie, Kozue Sakao, De-Xing Hou   The regulation effects of Ampelopsis Grossedentata Derived dihydromyricetin on bile acids secretion and microbiota metabolites in metabolic syndrome   International conference

    日本農芸化学会2020大会 

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    Event date: 2020.3

    Language:English   Presentation type:Oral presentation (general)  

  • De-Xing Hou   Protein kinases as molecular targets for cancer chemopreventionProtein kinases as molecular targets for cancer chemoprevention by dietary polyphenols   Invited International conference

    International Conference for Food Factors 2019 (ICoFF2019) 

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    Event date: 2019.12

    Language:English   Presentation type:Oral presentation (invited, special)  

  • Xu-Chi Pan, Keyu Chen, Kun Xie, Kozue Sakao, De-Xing Hou   Wasabi 6-methylthiohexyl isothiocyanate enhances Sirtuin 1 expression by modulating AMPK and Nrf2 pathways   International conference

    International Conference for Food Factors 2019 (ICoFF2019) 

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    Event date: 2019.12

    Language:English   Presentation type:Poster presentation  

  • Keyu Chen, Kun Xie, Kozue Sakao, De-Xing Hou   Preventive effect of allicin-free garlic on gut microbiome dysbiosis   International conference

    . International Conference for Food Factors 2019 (ICoFF2019) 

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    Event date: 2019.12

    Language:English   Presentation type:Poster presentation  

  • Kun Xie, Keyu Chen, Xi He, Kozue Sakao, De-Xing Hou   The regulation effects of Ampelopsis Grossedentata Derived dihydromyricetin on bile acids secretion and microbiota metabolites in metabolic syndrome   International conference

    International Conference for Food Factors 2019 (ICoFF2019) 

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    Event date: 2019.12

    Language:English   Presentation type:Poster presentation  

  • 侯 徳興   植物色素研究会第31回集会. アントシアニンパラドックスの解明に挑む:腸内細菌がキープレーヤー?   Invited International conference

    植物色素研究会第31回集会 

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    Event date: 2019.11

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

  • De-Xing Hou   Melioration Effects and Mechanisms of Garlic on Dyslipidemia and Gut Microbiome Dysbiosis   International conference

    Food for Health International Conference 2019 (FOHIC2019) 

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    Event date: 2019.10

    Language:English   Presentation type:Oral presentation (invited, special)  

    Venue:Wroclaw, Poland  

  • De-Xing Hou   Protein Kinases as Molecular Targets for Cancer Chemoprevention by Dietary Polyphenols   Invited International conference

    Asia Pacific Nutrigenomics Nutrigenetics Organisation (APNNO2018)Biennial Conference 

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    Event date: 2018.12

    Language:English   Presentation type:Oral presentation (invited, special)  

  • De-Xing Hou   Local food resources for human health: From lab bench studies to healthy table innovations   Invited International conference

    Latin Food 2018 

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    Event date: 2018.11

    Language:English   Presentation type:Oral presentation (keynote)  

  • Keyu Chen, Kozue Sakao, De-Xing Hou   Garlic supplements as potential prebiotics for gut microbiome   International conference

    Latin Food 2018 

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    Event date: 2018.11

    Language:English   Presentation type:Poster presentation  

    Venue:Marriott puerto Vallarta Resort & Spa, Mexico. Mexico  

  • Kun Xie, Xi He, Kozue Sakao, De-Xing Hou   The preventive effects and mechanisms of Ampelopsis grossedentata (Vine tea) on metabolic syndrome and gut dysbiosis   International conference

    Latin Food 2018 

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    Event date: 2018.11

    Language:English   Presentation type:Oral presentation (general)  

    Venue:Marriott puerto Vallarta Resort & Spa, Mexico  

  • Hironobu Nakano, Shusong Wu, Kozue Sakao, De-Xing Hou   Preventive effects and mechanisms of non-alcoholic fatty liver disease (NAFLD) by bilberry   International conference

    Latin Food 2018 

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    Event date: 2018.11

    Language:English   Presentation type:Oral presentation (general)  

  • 楢本 龍之介、高山 耕二、坂尾 こず枝、侯 德興   メタボローム解析による薩摩黒鴨の肉質特徴の解明   International conference

    平成30年度日本栄養・食糧学会 九州・沖縄支部大会 

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    Event date: 2018.11

    Language:Japanese   Presentation type:Oral presentation (general)  

  • 新村 麻弥、木戸 めぐみ、坂尾 こず枝、侯 德興   調理加工における黒豆の機能性の変化に関する研究   International conference

    平成30年度日本栄養・食糧学会 九州・沖縄支部大会 

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    Event date: 2018.11

    Language:Japanese   Presentation type:Oral presentation (general)  

  • 栗田 志保, 久永 絢美, 伍 樹松, 矢野 敏史, 坂尾 こず枝, 橋本 文雄, 侯 德興   茶プルプロガリンの抗炎症機能及び細胞内分子機構に関する研究   International conference

    第23回日本フードファクター学会学術集会 

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    Event date: 2018.9

    Language:Japanese   Presentation type:Poster presentation  

  • De-Xing Hou   Anthocyanins food innovation: from lab bench to healthy dining table   Invited International conference

    International Conference on Food Science and Health 2018 (ICFSH2018) 

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    Event date: 2018.9

    Language:English   Presentation type:Oral presentation (invited, special)  

  • De-Xing Hou   The preventive effects and molecular mechanisms of berry polyphenols in experimental nonalcoholic steatohepatitis (NASH).   Invited International conference

    256th Anerican Chemistry Society (ACS) National Meeting  Anerican Chemistry Society (ACS)

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    Event date: 2018.8

    Language:English   Presentation type:Oral presentation (invited, special)  

  • 中野拓宜、伍樹松、坂尾こず枝、侯 徳興   ビルベリーによる非アルコール性脂肪性肝炎の予防効果及び作用機構   International conference

    第22回日本フードファクター学会大会  日本フードファクター学会

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    Event date: 2017.12

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:藤沢  

  • Hou DX   A systematic project from animal meat production, meat processing, nutritional and functional assessment to human health   Invited International conference

    Food for Health International Conference 2017 (FOHIC2017)  FOHIC

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    Event date: 2017.10

    Language:English   Presentation type:Oral presentation (invited, special)  

  • Yuki Shioiridani, De-Xing Hou, Kozue Sakao   Structure activity relationship of flavonoids derivatives against HCT116 human colon carcinoma   International conference

    Food for Health International Conference 2017 (FOHIC2017)  FOHIC

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    Event date: 2017.10

    Language:English   Presentation type:Poster presentation  

    Venue:Changsha, China  

  • Shohei Minami, De-Xing Hou, Kozue Sakao   Differential inhibition effect of colon cancer by quercetin and acetylated quercetin   International conference

    Food for Health International Conference 2017 (FOHIC2017)  FOHIC

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    Event date: 2017.10

    Language:English   Presentation type:Poster presentation  

    Venue:Changsha, China  

  • Rei Takada, De-Xing Hou, Kozue Sakao   Synthesis of quercetin derivatives and determination of their anti-tumor activity in HCT116 human colon carcinoma   International conference

    Food for Health International Conference 2017 (FOHIC2017)  FOHIC

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    Event date: 2017.10

    Language:English   Presentation type:Poster presentation  

    Venue:Changsha, China  

  • Keyu Chen, Yumi Hatada, Kozue Sakao, Shusong Wu, Fumio Hashimoto, De-Xing Hou   Ganoderma lucidum as a chemosensitizer to improve the anti-cancer effects in human colon cancer cells   International conference

    Food for Health International Conference 2017 (FOHIC2017)  FOHIC

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    Event date: 2017.10

    Language:English   Presentation type:Poster presentation  

    Venue:Changsha, China  

  • Shiho Kurita, Ayami Hisanaga, Shusong Wu, Satoshi Yano, Kozue Sakao, Fumio Hashimoto, De-Xing Hou   Anti-inflammatory effects and the molecular mechanisms of tea purpurogallin   International conference

    Food for Health International Conference 2017 (FOHIC2017)  FOHIC

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    Event date: 2017.10

    Language:English   Presentation type:Poster presentation  

    Venue:Changsha, China  

  • Ai Murakami, Kozue Sakao, Cho Sho Kuniaki Kawano, Kenichi Iwai, Yoshikazu Takase, De-Xing Hou   Anticancer Activity of Cordyceps Militaris Spirits in HCT-116 Colon Cancer Cells   International conference

    Food for Health International Conference 2017 (FOHIC2017)  FOHIC

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    Event date: 2017.10

    Language:English   Presentation type:Poster presentation  

    Venue:Changsha, China  

  • Hou DX   Polyphenols from Lonicera caerulea L. berry ameliorate experimental nonalcoholic steatohepatitis (NASH) through dual modulation of antioxidant and in?ammatory mediators   Invited International conference

    8th International Conference on Polyphenols and Health (ICPH2017).  ICPH

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    Event date: 2017.10

    Language:English   Presentation type:Oral presentation (invited, special)  

    Venue:Quebec, Canada  

  • 章 超、坂尾こず枝、村上 愛、河野邦晃、 岩井謙一、髙瀬良和、侯 徳興   サツマイモ焼酎のチャーガスピリッツの機能性解析   International conference

    日本食品科学工学会第64回大会  日本食品科学工学会

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    Event date: 2017.8

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:藤沢  

  • 侯 徳興   DNA マイクロアレイから見えたイソチオシアネート化合物の生体調節機能、シンポジウムS12 「食と遺伝子発現」   Invited

    第71回日本栄養・食糧学会大会  日本栄養・食糧学会

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    Event date: 2017.5

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Venue:沖縄  

  • 村上 愛、坂尾 こず枝、章 超、髙瀬良和、岩井謙一、侯 德興   サツマイモ焼酎により作製したチャーガスピリッツの抗炎症能解析  

    第71回日本栄養・食糧学会大会  日本栄養・食糧学会

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    Event date: 2017.5

    Language:Japanese   Presentation type:Poster presentation  

    Venue:沖縄  

  • 矢野敏史、坂尾こず枝、侯徳興   ワサビ機能性成分の抗癌作用および抗癌剤との併用効果の解析  

    日本農芸化学会2017年度大会  日本農芸化学会

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    Event date: 2017.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:京都  

  • Hou DX   Anthocyanin foods: from lab bench to kitchen table   International conference

    The International Conference on Bioscience 2016  ICB Society

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    Event date: 2016.7

    Language:English   Presentation type:Oral presentation (invited, special)  

    Venue:Bali, Indonesia  

  • Hou DX   The Beneficial Effects of Food Factors on Neuronal Signaling and Function in Aging   International conference

    The 10th International Symposium for Aging (ISA)  ISA Society

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    Event date: 2016.7

    Language:English   Presentation type:Oral presentation (keynote)  

    Venue:Gwangju, Korea  

  • Hou DX   Dynamic modulation of Nrf2/Keap1 system by nutraceuticals   International conference

    Pacifichem 2015  Pacifichem Society

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    Event date: 2015.12

    Language:English   Presentation type:Oral presentation (general)  

    Venue:Hawaii, USA  

  • Hou DX   Garlic and health benefit: insights into the molecular mechanisms   Invited International conference

    International Conference of Food Factor 2015 (ICoFF2015)  ICoFF Society

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    Event date: 2015.11

    Language:English   Presentation type:Oral presentation (invited, special)  

    Venue: Soul, Korea  

  • Noridomi K, Sakao K, Hou DX   Terpene-induced program cell death in human colon cancer cells: Structure-activity relationship and mechanisms   International conference

    International Conference on Polyphenols and Health (ICPH 2015)  ICoFF Society

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    Event date: 2015.11

    Language:English   Presentation type:Oral presentation (general)  

    Venue: Soul, Korea  

  • Yano Y, Sakao K, Hou DX   Wasabi 6-MSITC as a chemosensitizer to improve the anti-cancer effects in human colon cancer cells   International conference

    International Conference on Polyphenols and Health (ICPH 2015)  ICoFF Society

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    Event date: 2015.11

    Language:English   Presentation type:Poster presentation  

    Venue: Soul, Korea  

  • Sakao K, Hou DX   Quercetin derivatives induced p53 independent apoptosis in HCT116 human colon carcinoma   International conference

    International Conference on Polyphenols and Health (ICPH 2015)  ICPH

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    Event date: 2015.10

    Language:English   Presentation type:Poster presentation  

    Venue:Tours, France  

  • Wu SS, He X, Sakao K, Hou DX   Protective Effects and Mechanisms of Blue Honeysuckle on Nonalcoholic Steatohepatitis in Mice Model   International conference

    International Conference of Food Factor 2015 (ICoFF2015)  ICoFF Society

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    Event date: 2015.10

    Language:English   Presentation type:Poster presentation  

    Venue: Soul, Korea  

  • 章超、坂尾こず枝、廣眞梨子、髙瀬良和、岩井謙一、侯徳興   芋焼酎のチャーガスピリッツの機能性解析   International conference

    第67回日本生物工学会大会  日本生物工学会

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    Event date: 2015.10

    Language:Japanese   Presentation type:Poster presentation  

    Venue:鹿児島  

  • 章超、坂尾こず枝、廣眞梨子、髙瀬良和、岩井謙一、侯徳興   サツマイモ焼酎のチャーガスピリッツの抽出物の抗炎症効果について  

    平成27年度日本醸造学会大会 

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    Event date: 2015.10

    Language:Japanese   Presentation type:Oral presentation (general)  

  • Hou DX   From food function, agricultural production to health dining table: Anthocyanin as a case.   Invited International conference

    1st NDSU Annual Conference on Food for Health  North Dakota State University, USA

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    Event date: 2015.7

    Language:English   Presentation type:Oral presentation (invited, special)  

    Venue:Fargo, North Dakota  

  • Hou DX   Dietary polyphenols target protein kinases for cancer chemoprevention   Invited International conference

    Cancer Prevention: Fulfilled Promises, Translational Challenges and Future Directions  Gdansk University

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    Event date: 2015.6

    Language:English   Presentation type:Oral presentation (invited, special)  

    Venue:Gdansk, Poland  

  • Sakao K, Hou DX   Apoptosis induction of Quercetin derivatives in human colon carcinoma cells:   Invited International conference

    International Symposium on Current Advances in Radiobiology, Stem Cells and Cancer Research 

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    Event date: 2015.2

    Language:English   Presentation type:Poster presentation  

    Venue:New Delhi, India  

  • 矢野 敏史、坂尾 こず枝、侯 徳興   MEK1/2は死のシグナルとしてワサビ6-MSITCによるアポトーシスやオートファジーに働く  

    第19回日本フードファクター学会  第19回日本フードファクター学会

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    Event date: 2014.11

    Language:Japanese  

    Venue:鹿児島  

    国内学会

  • Hou DX   Nutrigenomics of Natural Bioactive Compounds: from gene expression profiling to molecule targeting   International conference

    5th Annual Conference of American Council for Medicinally Active Plants  5th Annual Conference of American Council for Medicinally Active Plants

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    Event date: 2014.6

    Language:English  

    Venue:Fargo, North Dakota, USA  

    国際学会

  • 章 超、坂尾 こず枝、小野 友愛、髙瀬 良和、岩井 謙一、侯 徳興   サツマイモ焼酎の冬虫夏草スピリッツの抽出物によるHL-60細胞のアポトーシス誘導  

    日本農芸化学会2014年度大会  日本農芸化学会2014年度大会

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    Event date: 2014.3

    Language:Japanese  

    Venue:東京  

    国内学会

  • Hou DX   Garlic organosulfur compounds as a potential anti-inflammatory agent: molecular and animal evidence   International conference

    Antioxidants and redox process in health - Bilateral Meeting of Brazil-Japan  Antioxidants and redox process in health - Bilateral Meeting of Brazil-Japan

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    Event date: 2013.10

    Language:English  

    Venue:Sao Paulo, Brazil.  

    国際学会

  • Hou DX   Dynamic Modulation of Nrf2/Keap1 System by Polyphenols   International conference

    VI International Conference on Polyphenols and Health (VI ICPH)  VI International Conference on Polyphenols and Health (VI ICPH)

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    Event date: 2013.10

    Language:English  

    Venue:Buenos Aires, Argentina  

    国際学会

  • Hou DX   Inhibitory effect and mechanism of blue honeysuckle on adjuvant-induced arthritis   International conference

    7th International Workshop on Anthocyanins - IWA 2013  7th International Workshop on Anthocyanins - IWA 2013

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    Event date: 2013.9

    Language:English  

    Venue:Porto, Portugul  

    国際学会

  • 松井 直子、向井 理恵、侯 徳興、河村 知志、根本 尚夫、二川 健、寺尾 純二   酸化ストレス上昇を伴う廃用性筋萎縮に対する抗酸化プレニルケルセチンの効果  

    第67回日本栄養・食糧学会大会  第67回日本栄養・食糧学会大会

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    Event date: 2013.5

    Language:Japanese  

    Venue:名古屋  

    国内学会

  • Hou DX   Nutrigenomics of phytochemicals: From expression profiling, cell signaling to molecule targeting   International conference

    中国 第11回動物栄養学会  中国 第11回動物栄養学会

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    Event date: 2012.10

    Language:English  

    Venue:中国 長沙  

    国際学会

  • Hou DX   Molecular basis for flavonoids: from gene expression profiling to molecule targeting   International conference

    13th Congress of the International Society for Ethnopharmacology  13th Congress of the International Society for Ethnopharmacology

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    Event date: 2012.9

    Language:English  

    Venue:オーストリア、グラッズ  

    国際学会

  • 侯 徳興   ポリフェノールとプロテインキナーゼのケミカルバイオロジー  

    農芸化学会西日本支部定例会  農芸化学会西日本支部定例会

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    Event date: 2012.6

    Language:Japanese  

    Venue:福岡  

    国内学会

  • 侯 徳興   アントシアニンとアンチエイジング  

    第28回臨床フリーラジカル会議-フリ-ラジカルとアンチエイジング  第28回臨床フリーラジカル会議-フリ-ラジカルとアンチエイジング

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    Event date: 2012.1

    Language:Japanese  

    Venue:京都  

    国内学会

  • 侯 徳興   鹿児島の機能性食材およびその魅力  

    アジアの酒食連携シンポジウム  アジアの酒食連携シンポジウム

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    Event date: 2011.12

    Language:Japanese  

    Venue:鹿児島  

    その他

  • 侯 徳興   焼酎粕及びその処理物の免疫増強能  

    かごしま「食と健康」フォーラム2011  かごしま「食と健康」フォーラム2011

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    Event date: 2011.12

    Language:Japanese  

    Venue:鹿児島  

    その他

  • Hou DX   The selectivity and impact of polyphenols-protein kinases interactions for chemoprevention   International conference

    International Conference of Food Factor 2011  International Conference of Food Factor 2011

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    Event date: 2011.11

    Language:English  

    Venue:台湾  

    国際学会

  • Hou DX   The impact of dietary polyphenols as protein kinase modulators   International conference

    2011 Annual Conference of International Society for Nutraceuticals and Functional Foods (2011 ISNFF)  2011 Annual Conference of International Society for Nutraceuticals and Functional Foods (2011 ISNFF)

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    Event date: 2011.11

    Language:English  

    Venue:札幌  

    国際学会

  • Hou DX   Polyphenols act as protein kinase inhibitors to mediate cellular signaling for chemoprevention   International conference

    2010 International Symposium on Nature Bioactive Products: Advance in Human Health and Animal Performance  2010 International Symposium on Nature Bioactive Products: Advance in Human Health and Animal Performance

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    Event date: 2010.9

    Language:English  

    Venue:中国、長沙  

    国際学会

  • 侯 徳興、益崎智子、石田寿子、谷川俊祐、橋本文雄、藤井 信   茶テアシネシンによるCOX-2遺伝子発現の制御機構  

    第64回日本栄養・食糧学会大会  第64回日本栄養・食糧学会大会

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    Event date: 2010.5

    Language:Japanese  

    Venue:徳島  

    国内学会

  • 坂尾 こず枝、藤井 信、侯 徳興   化学修飾によるケルセチンの構造活性の解析  

    日本農芸化学会2010大会  日本農芸化学会2010大会

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    Event date: 2010.3

    Language:Japanese  

    Venue:東京  

    国内学会

  • Hou DX   Flavonoids as anti-inflammatory compounds: Targeting signaling and molecules.   International conference

    Inflammation 2010: Inflammatory cell signaling mechanisms.  Inflammation 2010: Inflammatory cell signaling mechanisms.

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    Event date: 2010.1

    Language:English  

    Venue:Luxembourg  

    国際学会

  • Hou DX   Molecular Basis Underlying Cancer Chemoprevention of Natural Products: From Signaling Network to Gene Expression Profiling  

    The 2nd Joint Meeting of Kagoshima University (Japan) Chosun University (Korea) on Relationship between Protein Activity Control and Natural Products  The 2nd Joint Meeting of Kagoshima University (Japan) Chosun University (Korea) on Relationship between Protein Activity Control and Natural Products

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    Event date: 2009.9

    Language:Japanese  

    Venue:Gwangju, Korea  

    研究会

  • 侯 徳興、陳 継華、 藤井 信   DNAマイクロアレイを用いたワサビ6-MSITC抗炎症作用の標的遺伝子の同定  

    第63回日本栄養・食糧学会大会  第63回日本栄養・食糧学会大会

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    Event date: 2009.5

    Language:Japanese  

    Venue:長崎  

    国内学会

  • Hou DX   Anti-inflammation activity of 6-(methylsulfinyl) hexyl isothiocyanate, an active ingredient in Japanese wasabi: COX-2 as a target.   International conference

    Italian-Japanese Joint Symposium: Natural products and functional foods  Italian-Japanese Joint Symposium: Natural products and functional foods

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    Event date: 2008.6

    Language:English  

    Venue:イタリア、サレルノ  

    国際学会

  • 侯 徳興, 谷川俊祐、藤井 信   ポリフェノールのタンパク質ユビキチン化に及ぼす影響:ケルセチンを例として  

    第62回日本栄養・食糧学会大会  第62回日本栄養・食糧学会大会

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    Event date: 2008.5

    Language:Japanese  

    Venue:埼玉  

    国内学会

  • Hou DX   Bilberry anthocyanins and biological activities   International conference

    3rd International Conference on Polyphenols and Health (ICPH2007)  3rd International Conference on Polyphenols and Health (ICPH2007)

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    Event date: 2007.11

    Language:English  

    Venue:京都  

    国際学会

  • Hou DX   Anthocyanins and health: chemopreventive activities and molecular targets   International conference

    3rd ICPH Satellite Symposium in Kagoshima (SSK)  3rd ICPH Satellite Symposium in Kagoshima (SSK)

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    Event date: 2007.11

    Language:English  

    Venue:鹿児島  

    国際学会

  • Hou DX   Anthocyanins-more than nature’s color: Chemopreventive activities and molecular targets   International conference

    12th World Congress on Advances in Oncology  12th World Congress on Advances in Oncology

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    Event date: 2007.10

    Language:English  

    Venue:ギリシア  

    国際学会

  • Hou DX   アントシアニンとヒトの健康:細胞研究よりのエビデンス(Anthocyans and human health: evidence from cellular investigations)   International conference

    第232回米国化学会および展覧会(American Chemical Society: 232nd National Meeting & Exposition )  第232回米国化学会および展覧会(American Chemical Society: 232nd National Meeting & Exposition )

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    Event date: 2006.9

    Language:English  

    Venue:米国  

    国際学会

  • Hou DX   Wasabi 6-(methylsulfinyl)hexyl isothiocyanate, a chemopreventive compound, modulates the expression of cyclooxygenase-2 and inducible nitric oxide synthase in LPS-stimulated mouse macrophages   International conference

    第20回国際生化学、分子生物学大会(20th IUBMB International Congress of Biochemistry and Molecular Biology)(20th IUBMB International Congress of Biochemistry and Molecular Biology)  第20回国際生化学、分子生物学大会(20th IUBMB International Congress of Biochemistry and Molecular Biology)(20th IUBMB International Congress of Biochemistry and Molecular Biology)

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    Event date: 2006.6

    Language:English  

    Venue:京都  

    国際学会

  • Hou DX   食品機能成分のニュートリゲノミックス:アントシアニンを例として(Nutrigenomics of bioactive food components: the case of anthocyans )   International conference

    国際シンポジウム:食品・栄養ゲノミックスのパラダイム・シフト(The international Symposium Paradigm Shift: Foodomics/Nutrigenomics 2006)  国際シンポジウム:食品・栄養ゲノミックスのパラダイム・シフト(The international Symposium Paradigm Shift: Foodomics/Nutrigenomics 2006)

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    Event date: 2006.2

    Language:English  

    Venue:韓国  

    国際学会

  • Hou DX   Apoptosis induction by nutraceutical compounds: targeting reactive oxygen species (ROS) and mitochondria.   International conference

    Pacifichem2005  Pacifichem2005

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    Event date: 2005.12

    Language:English  

    Venue:米国  

    国際学会

  • 侯 徳興、柳田崇至、宇都 拓洋、益﨑智子、藤井 信   アントシアニジンのCOX-2遺伝子発現抑制: 構造と活性の関係およびその分子機構  

    第27回日本分子生物学会  第27回日本分子生物学会

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    Event date: 2005.12

    Language:Japanese  

    Venue:福岡  

    国内学会

  • Hou DX   Molecular Characterization of Cancer Chemopreventive Effects of Anthocyanins.   International conference

    6th International Conference and Exhibition on Nutraceuticals and Functional Foods.  6th International Conference and Exhibition on Nutraceuticals and Functional Foods.

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    Event date: 2005.10

    Language:English  

    Venue:米国  

    国際学会

  • 侯徳興   COX-2 遺伝子を用いた食品非栄養素の抗炎症・抗癌能の分子機構の解析.  

    第59回日本栄養・食糧学会大会  第59回日本栄養・食糧学会大会

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    Event date: 2005.5

    Language:Japanese  

    Venue:東京  

    国内学会

  • Hou DX   ポリフェノール化合物による癌細胞アポトーシスの誘導およびその分子機構:活性酸素とミトコンドリアの関与(Molecular Mechanism of Apoptosis Induction by Polyphenolic Compounds: Targeting Reactive Oxygen Species (ROS) and Mitochondria)   International conference

    世界抗感染学大会(World Conference on Dosing of Antiinfectives)  世界抗感染学大会(World Conference on Dosing of Antiinfectives)

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    Event date: 2004.9

    Language:English  

    Venue:ドイツ  

    国際学会

  • Hou DX   レインによる癌細胞のアポトーシスは活性酸素非依存のミトコンドリア死の経路が含まれている(Involvement of Reactive Oxygen Species-independent Mitochondrial Death Pathway in Rhein-induced Apoptosis)   International conference

    2004年アジア太平洋地区国際腫瘍生物学・医学大会および第21回国際腫瘍標識物学術会議(Asia-Pacific Conference of Tumor Biology and Medicine, 2004; 21st International Academy of Tumor Marker Oncology Conference)  2004年アジア太平洋地区国際腫瘍生物学・医学大会および第21回国際腫瘍標識物学術会議(Asia-Pacific Conference of Tumor Biology and Medicine, 2004; 21st International Academy of Tumor Marker Oncology Conference)

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    Event date: 2004.8

    Language:English  

    Venue:中国  

    国際学会

  • Hou DX   アントシアニンは、がんの化学予防作用を有するか? - 分子作用機構の紹介( ChemoprevenDo Anthocyanins Contribute toCancerChemoprevention? - Introduction to Molecular Evidence - )   International conference

    3rd International Workshop on Anthocyanins, IWA2004(第3回アントシアニン国際ワークショップ)  3rd International Workshop on Anthocyanins, IWA2004(第3回アントシアニン国際ワークショップ)

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    Event date: 2004.1

    Language:English  

    Venue:オーストラリア  

    国際学会

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Awards

  • 2020年度日本農芸化学会西日本支部奨励賞(学生)

    2021.2   日本農芸化学会  

  • Preventive effects and mechanisms of non-alcoholic fatty liver disease (NAFLD) by bilberry

    2018.11   Latin Food 2018"-Oral presentation Award by"Latin Food " International Society  

    Hironobu Nakano, Shusong Wu, Kozue Sakao, De-Xing Hou,

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    Award type:Award from international society, conference, symposium, etc.  Country:Mexico

  • Mol Nutr Food Res 雑誌優秀論文賞

    2017.4   Mol Nutr Food Res雑誌編集長  

    Wu S, Yano S, Hisanaga A, He X, He J, Sakao K, Hou DX

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    Award type:Honored in official journal of a scientific society, scientific journal  Country:Germany

  • Poster Presentation Award of Food for Health International Conference (FOHIC2016).

    2016.3   Food for Health International Society  

    Ayami Hisanaga, Rie Mukai, Kozue Sakao, Junji Terao, De-Xing Hou

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    Award type:Award from international society, conference, symposium, etc.  Country:Japan

  • Oral Presentation Award of Food for Health International Conference (FOHIC2016).

    2016.3   Food for Health International Society  

    Shusong Wu1, Kozue Sakao, De-Xing Hou

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    Award type:International academic award (Japan or overseas)  Country:Japan

  • Oral Presentation Award of Food for Health International Conference (FOHIC2016).

    2016.3   Food for Health International Society   Wasabi 6-MSITC induced apoptotic cell death of human colon cancer by triggering ERK1/2-mediated autophagic flux inhibition.

    Satoshi Yano, Kozue Sakao, Taichi Hara, and De-Xing Hou

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    Award type:Award from international society, conference, symposium, etc.  Country:Japan

  • 第20回日本フードファクター学会大会 Young Investigator Award (YIA) 賞

    2015.12   日本フードファクター学会  

    Wu SS, He X, Sakao K, Hou DX

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    Award type:International academic award (Japan or overseas)  Country:Japan

  • 第20回日本フードファクター学会大会 Young Investigator Award (YIA) 賞

    2015.12   日本フードファクター学会   Wasabi 6-MSITC as a chemosensitizer to improve the anti-cancer effects in human colon cancer cells

    Yano S. Sakao K, Hou DX

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    Award type:Award from Japanese society, conference, symposium, etc.  Country:Japan

  • Poster Award of International Conference of Food Factor 2015 (ICoFF2015)

    2015.11   ICoFF   Protective Effects and Mechanisms of Blue Honeysuckle on Nonalcoholic Steatohepatitis in Mice Model

    Wu SS, He X, Sakao K, Hou DX

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    Award type:Award from international society, conference, symposium, etc.  Country:Korea, Republic of

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Research Projects

  • 腸内細菌叢等の解析による奄美伝統野菜「ハンダマ」の健康維持機能の解明

    2021.4 - 2022.3

    公益財団法人 飯島藤十郎記念食品科学振興財団  公益財団法人 飯島藤十郎記念食品科学振興財団 学術研究助成金 

    侯 徳興

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    Grant type:Competitive

    Grant amount:\2000000

  • アントシアニンパラドックス解明に挑む: アントシアニンと腸内細菌の相互作用の研究

    2020.4 - 2023.3

    科学研究費補助金  基盤研究(C)

  • ニンニクによる腸内細菌叢失調及び脂質代謝異常症の予防効果並びに作用機構解明に関する研究

    2020.4 - 2021.3

    飯島藤十郎記念食品科学振興財団  飯島藤十郎記念食品科学振興財団 

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    Grant type:Competitive

  • 医福食農連携」による鹿児島県産 農畜水産物等の消費拡大に向けた高付加価値食品の開発

    2016.4 - 2019.3

    農林水産省  革新的技術開発・緊急展開事業(うち地域戦略プロジェクト) 

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    Grant type:Competitive

    医福食農連携」による鹿児島県産 農畜水産物等の消費拡大に向けた高付加価値食品の開発

 

Social Activities

  • ウェルネスかごしまへの誘い ~鹿児島黒食材と九州シェフズクラブとの饗宴

    Role(s): Lecturer

    鹿児島県  2019.9

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    Audience: Teachers, Researchesrs, General, Company, Civic organization, Governmental agency, Media

  • 国際交流~「33年間から見た私なりの日中交流」

    Role(s): Lecturer

    鹿児島県日中友好協会  2019.7

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    Audience: Teachers, General, Civic organization, Governmental agency

Academic Activities

  • JSoFF2014

    Role(s): Planning, management, etc., Supervision (editorial), Review, evaluation, Planning/Implementing academic research, Save/Restore

    Chair of JSoFF2014  2014.11

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    Type:Academic society, research group, etc. 

  • Food for Health International Conference 2017 (FOHIC2017) International contribution

    Role(s): Planning, management, etc., Panel moderator, session chair, etc., Supervision (editorial), Review, evaluation, Planning/Implementing academic research, Peer review, Save/Restore

    Co-chair  2017.10

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    Type:Competition, symposium, etc. 

  • Food for Health International Conference 2016 (FOHIC2016) International contribution

    Role(s): Planning, management, etc., Panel moderator, session chair, etc., Supervision (editorial), Review, evaluation, Save/Restore

    Chair of FOHIC2016  2016.3

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    Type:Competition, symposium, etc. 

  • International Conference for Food Factors 2019 (ICoFF2019) International contribution

    Role(s): Panel moderator, session chair, etc., Supervision (editorial), Save/Restore

    2019.12

     More details

    Type:Academic society, research group, etc. 

  • Food for Health International Conference 2019 (FOHIC2019)

    Role(s): Planning, management, etc., Panel moderator, session chair, etc., Supervision (editorial), Review, evaluation, Planning/Implementing academic research, Peer review, Save/Restore

    Chairman of FOHIS  2019.10

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    Type:Competition, symposium, etc. 

  • Food for Health International Conference 2018 (FOHIC2018)

    Role(s): Planning, management, etc., Panel moderator, session chair, etc., Supervision (editorial), Review, evaluation, Planning/Implementing academic research, Peer review, Save/Restore

    Chairman of FOHIS  2018.11

     More details

    Type:Competition, symposium, etc. 

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