Updated on 2024/10/04

写真a

 
TADASUKE OOKA, Ph.D.
 
Organization
Research Field in Medicine and Health Sciences, Medical and Dental Sciences Area Graduate School of Medical and Dental Sciences Health Research Course Infection and Immunity Associate Professor
Title
Associate Professor
Profile
1. Pathogenesis of emerging enteropathogen, #IEscherichia albertii#IR 2. Molecular epidemiology of pathogenic bacteria 3. Comparative genomics of pathogenic bacteria 4. Mechanism of horizontal gene transfer of virulence factors

Degree

  • 博士(医学) ( 2002.3   宮崎医科大学 )

Research Interests

  • phathogenesis

  • bacterial genomics

  • Escherichia albertii

  • pathogen

Research Areas

  • Life Science / Bacteriology

  • Life Science / Bacteriology  / Infectious diseases, pathogenic bacteria, genome, virulence mechanism

Education

  • Miyazaki Medical College

    - 2002.3

      More details

    Country: Japan

Research History

  • Kagoshima University   Research Field in Medicine and Health Sciences, Medical and Dental Sciences Area Graduate School of Medical and Dental Sciences Health Research Course Infection and Immunity   Associate Professor   Ph.D.

    2020.6 - 2025.5

  • たちばな医療専門学校   非常勤講師(兼任)

    2016.4

      More details

    Country:Japan

  • Kagoshima University   Research Field in Medicine and Health Sciences, Medical and Dental Sciences Area Graduate School of Medical and Dental Sciences Health Research Course Infection and Immunity   Lecturer

    2015.4 - 2020.5

  • 日南学園高等学校   田野看護専攻科   非常勤講師(兼任)

    2009.4 - 2013.3

      More details

    Country:Japan

  • 国立大学法人宮崎大学   医学部医学科感染症学講座微生物学分野   助教

    2007.4 - 2015.3

      More details

    Country:Japan

  • 宮崎看護専門学校   非常勤講師(兼任)

    2007.4 - 2015.3

      More details

    Country:Japan

  • 国立大学法人宮崎大学   医学部医学科感染症学講座微生物学分野   助手

    2004.4 - 2007.3

      More details

    Country:Japan

  •   医学部感染症学講座微生物病学分野   助手

    2003.10 - 2004.3

      More details

    Country:Japan

  •   医学部感染症学講座微生物病学分野   助手

    2003.5 - 2003.9

      More details

    Country:Japan

▼display all

Professional Memberships

  • 日本感染症学会

    2015.4

  • 日本食品微生物学会

    2012.8

  • 腸管出血性大腸菌感染症研究会

    2010.7

  • 日本ゲノム微生物学会

    2007.1 - 2016.3

  • 日本細菌学会

    2003.4

Committee Memberships

  • 毒素シンポジウム   運営委員  

    2024.1 - 2027.12   

      More details

    Committee type:Academic society

  • 日本学術振興会   科学研究費委員会専門委員  

    2018.12 - 2021.11   

 

Papers

  • Prevalence and characterization of Clostridium tetani strains in Amami islands .      2024Prevalence and characterization of Clostridium tetani strains in Amami islands

     More details

    Authorship:Lead author   Language:Japanese   Publishing type:Research paper (bulletin of university, research institution)  

  • Mizuno S, Tsukamura Y, Nishio S, Ishida T, Hasegawa D, Kosaka Y, Ooka T, Nishi J, Kasai M. .  Catheter-related bloodstream infection caused by Tsukamurella tyrosinosolvens identified by secA1sequencing in an immunocompromised child: a case report. .  Annals of Clinical Microbiology and Antimicrobials22 ( 1 ) 97   2023.11Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1186/s12941-023-00651-6

  • 大岡唯祐, 藺牟田直子, 西 順一郎, 森田喜紀, 今村真理, 重久朋史, 上野伸広, 相星壮吾, 山本真実, 新川奈緒美, 川村英樹, 馬場洋一, 柿澤広美, 伊藤 武, 後藤恭宏, 林 哲也 .  2018年のSalmonella enterica serovar Oranienburg菌血症集積事例株と同一クローン由来株による新たな感染事例と各地の食品取り扱い従事者からの同クローンの分離 .  病原微生物検出情報44   127 - 128   2023.8Reviewed

     More details

    Authorship:Lead author   Language:Japanese   Publishing type:Research paper (scientific journal)  

  • Koji Ichiki, Tadasuke Ooka, Tetsuhiro Shinkawa, Sakura Inoue, Maiko Hayashida, Daisuke Nakamura, Masaki Akimoto, Makoto Yoshimitsu, Hideki Kawamura, Masatoshi Nakamura, Yuki Obama, Yasuhiro Gotoh, Tetsuya Hayashi, Junichiro Nishi, Kenji Ishitsuka .  Genomic and phylogenetic characterization of Elizabethkingia anophelis strains: The first two cases of life-threatening infection in Japan .  Journal of infection and chemotherapy29 ( 4 ) 376 - 383   2023.1Reviewed International journal

     More details

    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    OBJECTIVE: Elizabethkingia anophelis causes meningitis, bloodstream infections, and respiratory infections in immunocompromised individuals. We examined two E. anophelis strains isolated from the first life-threatening cases caused by this species in Japan to determine the phylogenetic origin and genomic features of them. METHODS: We performed whole genome-based analysis to clarify the genetic relationship for the two strains (EK0004 and EK0079) and Elizabethkingia sp. strains isolated from worldwide and to characterize the genomic features such as the prevalence of virulence- and antimicrobial resistance (AMR)-related genes. PATIENTS: A 29-year-old man with hepatosplenic T-cell lymphoma and a 52-year-old man with systemic lupus erythematosus developed fatal bacteremia and meningitis due to E. anophelis, respectively. RESULTS: Two strains, EK0004 and EK0079, were genetically different but most closely related to the strains isolated from the largest outbreak in Wisconsin, USA from 2015 to 2016, and the strain isolated from cerebrospinal fluid of a patient in Florida, USA in 1982, respectively. The two strains contained AMR-related genes such as those encoding for an extended-spectrum β-lactamase and multiple metallo-β-lactamases and several virulence-related genes such as capsular polysaccharide synthesis gene clusters. CONCLUSIONS: Although further functional analyses are required to understand the virulence of these clones, these finding suggests that enough caution of E. anophelis infection in immunocompromised patients is required since the number of infections by this species is increasing outside Japan.

    DOI: 10.1016/j.jiac.2023.01.005

    PubMed

  • Tadasuke Ooka, Yasuhiro Gotoh, Shigeki Hatanaka, Miyuki Yoshimori, Kazutaka Nishitarumizu, Kanami Kojo, Hiroki Kosakamoto, Koji Sameshima, Yoichi Kuroki, Naomi Chibana, Yuriko Doi, Shuji Yoshino, Tetsuya Harada, Kazuko Seto, Tetsuya Ikeda, Hiroaki Miyanohara, Koichiro Nakayama, Mutsuyo Gokuden, Naoko Imuta, Hideki Kawamura, Yoshitoshi Ogura, Tetsuya Hayashi, Junichiro Nishi .  A Salmonella enterica serovar Oranienburg clone caused a cluster of bacteremia cases in persons with no recognizable underlying diseases in Japan. .  Open Forum Infectious Diseases10 ( 1 ) ofac695   2022.12Reviewed International journal

     More details

    Authorship:Lead author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    BACKGROUND: Salmonella enterica subspecies enterica serovar Oranienburg (SO) is a foodborne pathogen but rarely causes systemic infections such as bacteremia. Between July and September 2018, bacteremia cases caused by SO were identified in 12 persons without any underlying medical conditions in the southern Kyushu area of Japan. METHODS: Randomly amplified polymorphic DNA (RAPD) analysis was performed to investigate the genetic similarity of the 12 bacteremia-related strains and other Japanese isolates. Furthermore, a series of whole-genome sequence (WGS)-based phylogenetic analyses was performed with a global SO strain set (n = 1648). RESULTS: The resolution power of RAPD was insufficient to investigate the genetic similarity between the bacteremia-related strains and other strains. WGS-based phylogenetic analyses revealed that the bacteremia-related strains formed a tight cluster along with 2 strains isolated from asymptomatic carriers in 2018 in the same area, with a maximum within-cluster single-nucleotide polymorphism (SNP) distance of 11. While several strains isolated in the United States and the United Kingdom were found to be closely related to the bacteremia-related strains, 2 strains isolated in 2016 in the southern Kyushu area were most closely related, with SNP distances of 4-11 and 5-10, and had the same plasmids as the bacteremia-related strains. CONCLUSIONS: The 12 bacteremia cases identified were caused by a single SO clone. As none of the bacteremia patients had any underlying diseases, this clone may be prone to cause bacteremia. Although further analyses are required to understand its virulence, particular attention should be given to this clone and its close relatives in the surveillance of nontyphoidal salmonellae.

    DOI: 10.1093/ofid/ofac695

    PubMed

  • Sakura Arai, Tadasuke Ooka, Mizuha Shibata, Yuhki Nagai, Yuki Tokoi, Hiromi Nagaoka, Rika Maeda, Akihiko Tsuchiya, Yuka Kojima, Kenji Ohya, Takahiro Ohnishi, Noriko Konishi, Kayoko Ohtsuka, Yukiko Hara-Kudo .  Development of a novel real-time polymerase chain reaction assay to detect Escherichia albertii in chicken meat .  Foodborne Pathogens and Disease19 ( 12 ) 823 - 829   2022.12Reviewed International journal

     More details

    Language:English   Publishing type:Research paper (scientific journal)   Publisher:Mary Ann Liebert at Mary Ann Liebert, Inc.  

    DOI: 10.1089/fpd.2022.0042

  • Koji Nakae, Tadasuke Ooka, Koichi Murakami, Yukiko Hara-Kudo, Naoko Imuta, Yasuhiro Gotoh, Yoshitoshi Ogura, Tetsuya Hayashi, Yasuhiro Okamoto, and Junichiro Nishi .  Diversification of Escherichia albertii H-antigens and development of H-Genotyping PCR .  Frontiers in Microbiology12   737979 - 737979   2021.11Reviewed International journal

     More details

    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    Escherichia albertii is a recently recognized human enteropathogen that is closely related to Escherichia coli. As E. albertii sometimes causes outbreaks of gastroenteritis, rapid strain typing systems, such as the O- and H-serotyping systems widely used for E. coli, will be useful for outbreak investigation and surveillance. Although an O-genotyping system has recently been developed, the diversity of E. albertii H-antigens (flagellins) encoded by fliC genes remains to be systematically investigated, and no H-serotyping or genotyping system is currently available. Here, we analyzed the fliC genes of 243 genome-sequenced E. albertii strains and identified 73 sequence types, which were grouped into four clearly distinguishable types designated E. albertii H-genotypes 1-4 (EAHg1-EAHg4). Although there was a clear sign of intraspecies transfer of fliC genes in E. albertii, none of the four E. albertii H-genotypes (EAHgs) were closely related to any of the 53 known E. coli H-antigens, indicating the absence or rare occurrence of interspecies transfer of fliC genes between the two species. Although the analysis of more E. albertii strains will be required to confirm the low level of variation in their fliC genes, this finding suggests that E. albertii may exist in limited natural hosts or environments and/or that the flagella of E. albertii may function in a limited stage(s) in their life cycle. Based on the fliC sequences of the four EAHgs, we developed a multiplex PCR-based H-genotyping system for E. albertii (EAH-genotyping PCR), which will be useful for epidemiological studies of E. albertii infections.

    DOI: 10.3389/fmicb.2021.737979

    PubMed

  • YAHIRO Shunsuke, HARADA Seiya, OBARA Atsumi, IMUTA Naoko, OOKA Tadasuke, Nishi Junichiro .  A Survey of the Intestinal Carriage Rate of <i>Enterobacterales</i> Resistant to β-lactam Antibiotics in Kumamoto Prefecture .  Kansenshogaku Zasshi97 ( 5 ) 153 - 161   2023.9Reviewed

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:The Japanese Association for Infectious Diseases  

    <p>In order to investigate the spread of intestinal carriage of β-lactam antibiotics-resistant <i>Enterobacterales</i> (BLARE) in Kumamoto prefecture, we attempted to isolate them from 1,434 fecal samples received at our laboratory between April 2015 and March 2020, and 354 drug-resistant strains were isolated from 340 (23.7%) samples.</p><p>Of these, 343 (96.9%) strains were <i>Escherichia coli</i>, and ESBL-producing <i>E. coli</i> accounted for 305 (86.2%) of the 343 strains.</p><p>Furthermore, 133 (43.6%) of the strains were identified as belonging to the <i>E. coli</i> O25b-ST131 pandemic clonal group which has spread worldwide; thus, expansion of this clonal group was suggested as being one of the causes of the increase in the intestinal carriage rate of drug-resistant bacteria in kumamoto prefecture.</p><p>All of the ESBL producers isolated in this study were found to carry the <i>bla</i><sub>CTX-M</sub> gene: 210 (67.7%) strains carried the <i>bla</i><sub>CTX-M-9</sub> gene, 80 (25.8%) carried the <i>bla</i><sub>CTX-M-1</sub> gene, and 13 (4.2%) carried both the <i>bla</i><sub>CTX-M-1</sub> and <i>bla</i><sub>CTX-M-9</sub> genes, etc.</p><p>In addition, when the BLARE isolates were sorted by the types of facility from which the specimens were received, the isolation rate from infant facilities was particularly high, exceeding 35%, and horizontal transmission of several serotypes of ESBL-producing <i>E. coli</i> were detected at multiple facilities. Based on our findings, we suggest that infant facilities may be one of the most important reservoirs of ESBL producers.</p>

    DOI: 10.11150/kansenshogakuzasshi.e21037

  • Hideki Kawamura, Naoko Imuta, Tadasuke Ooka, Akari Shigemi, Masatoshi Nakamura, Kimiko Mougi, Yuki Obama, Ryuko Fukuyama, Syoko Arimura, Nao Murata, Hiroyuki Tominaga, Hiromi Sasaki, Satoshi Nagano, Noboru Taniguchi, Junichiro Nishi .  Impact of control measures including decolonization and hand hygiene for orthopaedic surgical site infection caused by methicillin-resistant Staphylococcus aureus at a Japanese tertiary-care hospital: evaluation of the transmission process by epidemiological and molecular analyses. .  Journal of Hospital InfectionS0195-6701(23)   00240-2   2023.7Impact of control measures including decolonization and hand hygiene for orthopaedic surgical site infection caused by methicillin-resistant Staphylococcus aureus at a Japanese tertiary-care hospital: evaluation of the transmission process by epidemiological and molecular analyses.Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: https://doi.org/10.1016/j.jhin.2023.07.011

  • Keiji Nakamura, Kazuko Seto, Kenichi Lee, Tadasuke Ooka, Yasuhiro Gotoh, Itsuki Taniguchi, Yoshitoshi Ogura, Jacques Georges Mainil, Denis Piérard, Tetsuya Harada, Yoshiki Etoh, Saori Ueda, Mitsuhiro Hamasaki, Junko Isobe, Keiko Kimata, Hiroshi Narimatsu, Jun Yatsuyanagi, Makoto Ohnishi, Sunao Iyoda, Tetsuya Hayashi .  Global population structure, genomic diversity and carbohydrate fermentation characteristics of clonal complex 119 (CC119), an understudied Shiga toxin-producing E. coli (STEC) lineage including O165:H25 and O172:H25. .  Microbial Genomics9 ( 3 ) 000959   2023.3Reviewed International coauthorship International journal

     More details

    Language:English   Publishing type:Research paper (scientific journal)   Publisher:Microbiology Society  

    <jats:p>Among Shiga toxin (Stx)-producing <jats:italic>
    <jats:named-content content-type="species">
    <jats:ext-link xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="uri" xlink:href="http://doi.org/10.1601/nm.3093" xlink:type="simple">Escherichia coli</jats:ext-link>
    </jats:named-content>
    </jats:italic> (STEC) strains of various serotypes, O157:H7 and five major non-O157 STEC (O26:H11, O111:H8, O103:H2, O121:H19 and O145:H28) can be selectively isolated by using tellurite-containing media. While human infections by O165:H25 STEC strains have been reported worldwide, their detection and isolation are not easy, as they are not resistant to tellurite. Systematic whole-genome sequencing (WGS) analyses have not yet been conducted. Here, we defined O165:H25 strains and their close relatives, including O172:H25 strains, as clonal complex 119 (CC119) and performed a global WGS analysis of the major lineage of CC119, called CC119 <jats:italic>sensu stricto</jats:italic> (CC119ss), by using 202 CC119ss strains, including 90 strains sequenced in this study. Detailed comparisons of 13 closed genomes, including 7 obtained in this study, and systematic analyses of Stx phage genomes in 50 strains covering the entire CC119ss lineage, were also conducted. These analyses revealed that the Stx2a phage, the locus of enterocyte effacement (LEE) encoding a type III secretion system (T3SS), many prophages encoding T3SS effectors, and the virulence plasmid were acquired by the common ancestor of CC119ss and have been stably maintained in this lineage, while unusual exchanges of Stx1a and Stx2c phages were found at a single integration site. Although the genome sequences of Stx2a phages were highly conserved, CC119ss strains exhibited notable variation in Stx2 production levels. Further analyses revealed the lack of SpLE1-like elements carrying the tellurite resistance genes in CC119ss and defects in rhamnose, sucrose, salicin and dulcitol fermentation. The genetic backgrounds underlying these defects were also clarified.</jats:p>

    DOI: 10.1099/mgen.0.000959

  • Yusuke Nomoto, Yuko Higashi, Youhei Uchida, Kazuyasu Fujii, Tadasuke Ooka, Takuro Kanekura .  Disseminated cutaneous sporotrichosis with intravascular granuloma .  The Journal of Dermatology49 ( 9 ) 301 - 302   2022.9Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/1346-8138.16429

  • Ruriko Nishida, Keiji Nakamura, Itsuki Taniguchi, Kazunori Murase, Tadasuke Ooka, Yoshitoshi Ogura, Yasuhiro Gotoh, Takehiko Itoh, Atsushi Toyoda, Jacques Georges Mainil, Denis Piérard, Kazuko Seto, Tetsuya Harada, Junko Isobe, Keiko Kimata, Yoshiki Etoh, Mitsuhiro Hamasaki, Hiroshi Narimatsu, Jun Yatsuyanagi, Mitsuhiro Kameyama, Yuko Matsumoto, Yuhki Nagai, Jun Kawase, Eiji Yokoyama, Kazuhiko Ishikawa, Takayuki Shiomoto, Kenichi Lee, Dongchon Kang, Koichi Akashi, Makoto Ohnishi, Sunao Iyoda and Tetsuya Hayashi .  The global population structure and evolutionary history of the acquisition of major virulence factor-encoding genetic elements in Shiga toxin-producing Escherichia coli O121:H19 .  Microbial Genomics7 ( 12 ) 000716   2021.12The global population structure and evolutionary history of the acquisition of major virulence factor-encoding genetic elements in Shiga toxin-producing Escherichia coli O121:H19Reviewed International coauthorship International journal

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    Shiga toxin (Stx)-producing Escherichia coli (STEC) are foodborne pathogens causing serious diseases, such as haemorrhagic colitis and haemolytic uraemic syndrome. Although O157:H7 STEC strains have been the most prevalent, incidences of STEC infections by several other serotypes have recently increased. O121:H19 STEC is one of these major non-O157 STECs, but systematic whole genome sequence (WGS) analyses have not yet been conducted on this STEC. Here, we performed a global WGS analysis of 638 O121:H19 strains, including 143 sequenced in this study, and a detailed comparison of 11 complete genomes, including four obtained in this study. By serotype-wide WGS analysis, we found that O121:H19 strains were divided into four lineages, including major and second major lineages (named L1 and L3, respectively), and that the locus of enterocyte effacement (LEE) encoding a type III secretion system (T3SS) was acquired by the common ancestor of O121:H19. Analyses of 11 complete genomes belonging to L1 or L3 revealed remarkable interlineage differences in the prophage pool and prophage-encoded T3SS effector repertoire, independent acquisition of virulence plasmids by the two lineages, and high conservation in the prophage repertoire, including that for Stx2a phages in lineage L1. Further sequence determination of complete Stx2a phage genomes of 49 strains confirmed that Stx2a phages in lineage L1 are highly conserved short-tailed phages, while those in lineage L3 are long-tailed lambda-like phages with notable genomic diversity, suggesting that an Stx2a phage was acquired by the common ancestor of L1 and has been stably maintained. Consistent with these genomic features of Stx2a phages, most lineage L1 strains produced much higher levels of Stx2a than lineage L3 strains. Altogether, this study provides a global phylogenetic overview of O121:H19 STEC and shows the interlineage genomic differences and the highly conserved genomic features of the major lineage within this serotype of STEC.

    DOI: 10.1099/mgen.0.000716

    PubMed

  • Sakura Arai, Satoko Yamaya, Kayoko Ohtsuka, Noriko Konishi, Hiromi Obata, Tadasuke Ooka, Shouhei Hirose, Akemi Kai, Yukiko Hara-Kudo .  Detection of Escherichia albertii in retail oysters .  Journal of Food Protection   2021.9Detection of Escherichia albertii in retail oystersReviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.4315/JFP-21-222

  • Nguyen Thi Thu Huong, Atsushi Iguchi, Ritsuko Ohata, Hisahiro Kawai, Tadasuke Ooka, Hiroshi Nakajima, Sunao Iyoda .  Distribution of novel Og-types in Shiga toxin-producing Escherichia coli isolated from healthy cattle .  Journal of Clinical Microbiology59 ( 3 ) e02624-20   2020.12Distribution of novel Og-types in Shiga toxin-producing Escherichia coli isolated from healthy cattleReviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)   Publisher:American Society for Microbiology  

    DOI: 10.1128/JCM.02624-20

  • Ja-Young Lee, Hidehisa Shimizu, Masahito Hagio, Satoru Fukiya, Masamichi Watanabe, Yasutake Tanaka, Ga-Hyun Joe, Hitoshi Iwaya, Reika Yoshitsugu, Keidai Kikuchi, Misaki Tsuji, Nanako Baba, Takuma Nose, Koji Tada, Taketo Hanai, Shota Hori, Akari Takeuchi, Yumiko Furukawa, Bungo Shirouchi, Masao Sato, Tadasuke Ooka, Yoshitoshi Ogura, Tetsuya Hayashi, Atsushi Yokota, and Satoshi Ishizuka .  12α-hydroxylated bile acid induces hepatic steatosis with dysbiosis in rats .  BBA Molecular and Cell Biology of Lipids1865 ( 12 ) 158811   2020.1212α-hydroxylated bile acid induces hepatic steatosis with dysbiosis in ratsReviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.bbalip.2020.158811

  • Fabiano T Romão, Fernando Henrique Martins, Rodrigo Tavanelli Hernandes, Tadasuke Ooka, Fernanda Fernandes Dos Santos, Denise Yamamoto, Alexis Bonfim-Melo, Tetsuya Hayashi, Waldir P Elias, Vanessa Sperandio, Tânia Aparecida Tardelli Gomes .  Genomic properties and temporal analysis of the interaction of an invasive Escherichia albertii with epithelial cells .  Frontiers Cellular and Infection Microbiology10   571088   2020.12Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3389/fcimb.2020.571088

  • 上村 晃秀, 眞鍋 佳月, 山本 真実, 岩切 忠文, 濱田 結花, 本田 俊郎, 川村 英樹, 藺牟田 直子, 大岡 唯祐, 西 順一郎 .  薬剤耐性菌検索体制の整備に関する研究(第III報) .  鹿児島県環境保健センター所報 ( 21 ) 65 - 68   2020.12薬剤耐性菌検索体制の整備に関する研究(第III報)

     More details

    Language:Japanese   Publishing type:Research paper (bulletin of university, research institution)  

  • 佐藤空見子,永井章子,小原準,遠藤千春,林哲也,大岡唯祐,瀬戸順次,村上光一 .  山形県内と畜場搬入豚のEscherichia albertii保菌状況及びその疫学的特徴 .  日本獣医師会雑誌73 ( 5 ) 265 - 273   2020.6山形県内と畜場搬入豚のEscherichia albertii保菌状況及びその疫学的特徴Reviewed

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:日本獣医師会  

    DOI: 10.12935/jvma.73.265

  • Tetsuya Ikeda, Toshie Shinagawa, Takuya Ito, Yuta Ohno, Akiko Kubo, Junichiro Nishi, Yasuhiro Gotoh, Yoshitoshi Ogura, Tadasuke Ooka, Tetsuya Hayashi .  Hypoosmotic stress induces flagellar biosynthesis and swimming motility in Escherichia albertii. .  Communications Biology3   87   2020.2Hypoosmotic stress induces flagellar biosynthesis and swimming motility in Escherichia albertii.Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)   Publisher:Springer Nature  

    DOI: 10.1038/s42003-020-0816-5

  • Keiji Nakamura, Kazunori Murase, Mitsuhiko P Sato, Atsushi Toyoda, Takehiko Itoh, Jacques Georges Mainil, Denis Piérard, Shuji Yoshino, Keiko Kimata, Junko Isobe, Kazuko Seto, Yoshiki Etoh, Hiroshi Narimatsu, Shioko Saito, Jun Yatsuyanagi, Kenichi Lee, Sunao Iyoda, Makoto Ohnishi, Tadasuke Ooka, Yasuhiro Gotoh, Yoshitoshi Ogura, Tetsuya Hayashi .  Differential dynamics and impacts of prophages and plasmids on the pangenome and virulence factor repertoires of STEC O145:H28 .  Microbial Genomics   2020.1Differential dynamics and impacts of prophages and plasmids on the pangenome and virulence factor repertoires of STEC O145:H28Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)   Publisher:Microbiology Society  

    DOI: 10.1099/mgen.0.000323

  • Toshiaki Kawabata, Yoichi Tenokuchi, Hiroki Yamakuchi, Hirotsugu Sameshima, Hirosuke Katayama, Takeshi Ota, Masatomo Tokunaga, Tomoko Takezaki, Suehiro Tamae, Toru Nakamura, Bin Chang, Yuichi Kodama, Naoko Imuta, Tadasuke Ooka, Yasuhiro Okamoto, Shigeru Suga, Junichiro Nish .  Concurrent Bacteremia Due to Non-vaccine Serotype 24F Pneumococcus in Twins: A Rapid Increase in Serotype 24F-invasive Pneumococcal Disease and its High Invasive Potential. .  The Pediatric Infectious Disease Journal39 ( 1 ) 85 - 87   2020.1Concurrent Bacteremia Due to Non-vaccine Serotype 24F Pneumococcus in Twins: A Rapid Increase in Serotype 24F-invasive Pneumococcal Disease and its High Invasive Potential.Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)   Publisher:Wolters Kluwer  

    DOI: 10.1097/INF.0000000000002508

  • Kentaro Kasama, Hiromi Fujita, Seigo Yamamoto, Tadasuke Ooka, Yasuhiro Gotoh, Yoshitoshi Ogura, Shuji Ando, and Tetsuya Hayashi .  Genomic features of Rickettsia heilongjiangensis revealed by intraspecies comparison and detailed comparison with Rickettsia japonica. .  Frontiers in Microbiology10   2787   2019.12Genomic features of Rickettsia heilongjiangensis revealed by intraspecies comparison and detailed comparison with Rickettsia japonica.Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)   Publisher:Frontiers Media S.A.  

    DOI: 10.3389/fmicb.2019.02787

  • Toshinobu Imashioya, Yuichi Kodama, Tadasuke Ooka, Shunsuke Nakagawa, Takuro Nishikawa, Takayuki Tanabe, Yasuhiro Okamoto, Naoko Imuta, Mari Kirishima, Akihide Tanimoto, Toyoyasu Koriyama, Junichiro Nishi, Yoshifumi Kawano .  Liver abscess due to Sterigmatomyces halophilus in a boy with acute lymphoblastic leukemiaSterigmatomyces halophilus .  Journal of Infection and Chemotherapy25 ( 12 ) 1047 - 1049   2019.12Liver abscess due to Sterigmatomyces halophilus in a boy with acute lymphoblastic leukemiaSterigmatomyces halophilusReviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.jiac.2019.05.021

  • Tadasuke Ooka, Kazuko Seto, Yoshitoshi Ogura, Keiji Nakamura, Atsushi Iguchi, Yasuhiro Gotoh, Mikiko Honda, Yoshiki Etoh, Tetsuya Ikeda, Wakana Sugitani, Takayuki Konno, Kimiko Kawano, Naoko Imuta, Kiyotaka Yoshiie, Yukiko Hara-Kudo, Koichi Murakami, Tetsuya Hayashi, Junichiro Nishi .  O-antigen biosynthesis gene clusters of Escherichia albertii: their diversity and similarity to E. coli gene clusters and the development of an O-genotyping method. .  Microbial Genomics   2019.11Reviewed

     More details

    Authorship:Lead author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:Microbiology Society  

    DOI: 10.1099/mgen.0.000314

  • Kanako Masuda, Tadasuke Ooka, Hiroko Akita, Takahiro Hiratsuka, Shinichi Takao, Mami Fukada, Kaori Inoue, Mikiko Honda, Junko Toda, Wakana Sugitani, Hiroshi Narimatsu, Taisei Ishioka, Shinichiro Hirai, Tsuyoshi Sekizuka, Makoto Kuroda, Yukio Morita, Tetsuya Hayashi, Hirokazu Kimura, Kazunori Oishi, Makoto Ohnishi, Shuji Fujimoto, Koichi Murakami .  Epidemiological Aspects of Escherichia albertii Outbreaks in Japan and Genetic Characteristics of the Causative Pathogen. .  Foodborne Pathogens and Disease17 ( 2 ) 144 - 150   2019.10Invited Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)   Publisher:Mary Ann Liebert at Mary Ann Liebert, Inc.  

    DOI: 10.1089/fpd.2019.2654

  • Yoko Arimizu, Yumi Kirino, Mitsuhiko P. Sato, Koichi Uno, Toshio Sato, Yasuhiro Gotoh, Frédéric Auvray, Hubert Brugere, Eric Oswald, Jacques G. Mainil, Kelly S. Anklam, Dörte Döpfer, Shuji Yoshino, Tadasuke Ooka, Yasuhiro Tanizawa, Yasukazu Nakamura, Atsushi Iguchi, Tomoko Morita-Ishihara, Makoto Ohnishi, Koichi Akashi, Tetsuya Hayashi, Yoshitoshi Ogura .  Large-scale genome analysis of bovine commensal Escherichia coli revealed that bovine-adapted E. coli lineages are serving as evolutionary sources of the emergence of human intestinal pathogenic strains .  Genome Research29 ( 9 ) 1495 - 1505   2019.8Large-scale genome analysis of bovine commensal Escherichia coli revealed that bovine-adapted E. coli lineages are serving as evolutionary sources of the emergence of human intestinal pathogenic strainsReviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)   Publisher:Cold Spring Harbor Laboratory Press  

    DOI: 10.1101/gr.249268.119.

  • 畠中成己、吉森みゆき、西垂水和隆、岩元ゆかり、小坂元博揮、鮫島幸二、古城圭馴美、内門 一、奥 章三、黒木暢一、松浦良樹、知花なおみ、上地修裕、田中直子、山下淳一、土井由利子、外城秀己、和田香織、下原美智子、宇田 英典、吉野修司、宮原聖奈、杉本貴之、中山浩一郎、御供田睦代、大坪充寛、後藤恭宏、小椋義俊、林 哲也、川村英樹、藺牟田直子、大岡唯祐、西 順一郎 .  鹿児島市を中心としたSalmonella enterica serovar Oranienburg 菌血症の集積 .  病原微生物検出情報40 ( 5 ) 91 - 92   2019.5Reviewed

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:国立感染症研究所  

  • Mauricio P. Lima, Denise Yamamoto, Ana Carolina de Mello Santos, Tadasuke Ooka, Rodrigo T. Hernandes, Mônica A. M. Vieira, Fernanda Fernandes dos Santos, Rosa Maria Silva, Tetsuya Hayashi, and Tânia A. T. Gomes .  Phenotypic characterization and virulence-related properties of Escherichia albertii strains isolated from children with diarrhea in Brazil. .  Pathogens and DIsease77 ( 2 ) ftz014   2019.3Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)   Publisher:OXFORD ACADEMIC  

    DOI: 10.1093/femspd/ftz014

  • Kazue Nakanaga, Yoshitoshi Ogura, Atsushi Toyoda, Mitsunori Yoshida, Hanako Fukano, Nagatoshi Fujiwara, Yuji Miyamoto, Noboru Nakata, Yuko Kazumi, Shinji Maeda, Tadasuke Ooka, Kazunari Tanigawa, Masamichi Goto, Satoshi Mitarai, Koichi Suzuki, Norihisa Ishii, Manabu Ato, Tetsuya Hayashi, and Yoshihiko Hoshino .  Naturally occurring a loss of a giant plasmid from Mycobacterium ulcerans subsp. shinshuense makes it non-pathogenic. .  Scientific Reports8 ( 1 ) 8218   2018.5Naturally occurring a loss of a giant plasmid from Mycobacterium ulcerans subsp. shinshuense makes it non-pathogenic.Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)   Publisher:Springer Nature  

    DOI: 10.1038/s41598-018-26425-1

  • Fabiano Romão, Rodrigo Hernandes, Tadasuke Ooka, Tetsuya Hayashi, Vanessa Sperandio, and Tania Gomes .  Complete Genome Sequence of Escherichia albertii Strain 1551-2, a Potential Extra and Intracellular Pathogen .  Genome announcements6 ( 9 ) e00075-18   2018.3Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)   Publisher:American Society for Microbiology  

    DOI: 10.1128/genomeA.00085-18

  • Yoshitoshi Ogura, Yasuhiro Gotoh, Takehiko Itoh, Mitsuhiko P. Sato, Kazuko Seto, Shyuji Yoshino, Junko Isobe, Yoshiki Etoh, Mariko Kurogi, Keiko Kimata, Eriko Maeda, Denis Piérard, Masahiro Kusumoto, Masato Akiba, Kiyoshi Tominaga, Yumi Kirino, Yuki Kato, Katsuhiko Shirahige, Tadasuke Ooka, Nozomi Ishijima, Ken-ichi Lee, Sunao Iyoda, Jacques Georges Mainil, Tetsuya Hayashi .  Population structure of Escherichia coli O26 : H11 with recent and repeated stx2 acquisition in multiple lineages. .  Microbial Genomics3   2017.11Population structure of Escherichia coli O26 : H11 with recent and repeated stx2 acquisition in multiple lineages.Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)   Publisher:MIcrobiology Society  

    DOI: 10.1099/mgen.0.000141

  • Yohsuke Ogawa, Kazumasa Shiraiwa, Yoshitoshi Ogura, Tadasuke Ooka, Sayaka Nishikawa, Masahiro Eguchi, Tetsuya Hayashi, Yoshihiro Shimoji .  Clonal Lineages of Erysipelothrix rhusiopathiae Responsible for Acute Swine Erysipelas in Japan Identified by Using Genome-Wide Single-Nucleotide Polymorphism Analysis. .  Applied and Environmental Microbiology83 ( 11 ) e00130-17   2017.5Clonal Lineages of Erysipelothrix rhusiopathiae Responsible for Acute Swine Erysipelas in Japan Identified by Using Genome-Wide Single-Nucleotide Polymorphism Analysis.Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)   Publisher:American Society for Microbiology  

    DOI: 10.1128/AEM.00130-17

  • Arzuba Akter, Tadasuke Ooka, Yasuhiro Gotoh, Seigo Yamamoto, Hiromi Fujita, Fumio Terasoma, Kouji Kida, Masakatsu Taira, Fumiko Nakadouzono, Mutsuyo Gokuden, Manabu Hirano, Mamoru Miyashiro, Kouichi Inari, Yukie Shimazu, Kenji Tabara, Atsushi Toyoda, Dai Yoshimura, Takehiko Itoh, Tomokazu Kitano, Mitsuhiko P. Sato, Keisuke Katsura, Shakhinur Islam Mondal, Yoshitoshi Ogura, Shuji Ando, Tetsuya Hayashi .  Extremely low genomic diversity of Rickettsia japonica distributed in Japan .  Genome Biology and Evolution9 ( 1 ) 124 - 133   2016.12Reviewed

     More details

    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1093/gbe/evw304

  • Shakhinur Mondal, Md Islam, Akira Sawaguchi, Md Asadulghani, Tadasuke Ooka, Yasuhiro Gotoh, Yasuhiro Kasahara, Yoshitoshi Ogura, and Tetsuya Hayashi .  Genes essential for the morphogenesis of the Shiga toxin 2-transducing phage from Escherichia coli O157:H7 .  Scientific Reports6   39036   2016.12Genes essential for the morphogenesis of the Shiga toxin 2-transducing phage from Escherichia coli O157:H7Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1038/srep39036

  • Mitsunori Yoshida, Kazue Nakanaga, Yoshitoshi Ogura, Atsushi Toyoda, Tadasuke Ooka, Yuko Kazumi, Satoshi Mitarai, Norihisa Ishii, Tetsuya Hayashi, Yoshihiko Hoshino .  The complete Genome Sequence of Mycobacterium " shinshuense ", a subspecies of M. ulcerans .  Genome Announcements   2016.8The complete Genome Sequence of Mycobacterium " shinshuense ", a subspecies of M. ulceransReviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Naoko Imuta, Tadasuke Ooka, Kazuko Seto, Ryuji Kawahara, Toyoyasu Koriyama, Tsuyoshi Kojyo, Atsushi Iguchi, Koichi Tokuda, Hideki Kawamura, Kiyotaka Yoshiie, Yoshitoshi Ogura, Tetsuya Hayashi, and Junichiro Nishi .  Phylogenetic analysis of enteroaggregative Escherichia coli (EAEC) isolated in Japan revealed the emergence of CTX-M-14-producing EAEC O25:H4 clones related to ST131 .  Journal of Clinical Microbiology   2016.6Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)   Publisher:American Society for Microbiology  

    DOI: 10.1128/JCM.00711-16

  • 村上光一, 伊豫田淳, 大西真, 深田真美, 増田加奈子, 前田詠里子, 麻生嶋七美, 成松浩志, 緒方喜久代, 戸田純子, 原田誠也, 大岡唯祐, 林哲也 他 .  Vero毒素産生株が散見される新興感染症原因菌 Escherichia albertiiについて .  病原微生物検出情報 (IASR)37 ( 5 ) 98 - 100   2016.5Invited

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:国立感染症研究所  

  • Bruna G. Garcia, Tadasuke Ooka, Yasuhiro Gotoh, Mônica A.M. Vieira, Denise Yamamoto, Yoshitoshi Ogura, Dennys M. Girão, Suely C.F. Sampaio, Alexis Bonfim Melo, Kinue Irino, Tetsuya Hayashi, Tânia A.T. Gomes .  Genetic relatedness and virulence properties of enteropathogenic Escherichia coli strains of serotype O119:H6 expressing localized adherence or localized and aggregative adherence-like patterns on HeLa cells .  International Journal of Medical Microbiology306   152 - 164   2016.2Genetic relatedness and virulence properties of enteropathogenic Escherichia coli strains of serotype O119:H6 expressing localized adherence or localized and aggregative adherence-like patterns on HeLa cellsReviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: doi:10.1016/j.ijmm.2016.02.008

  • Tadasuke Ooka, Yoshitoshi Ogura, Keisuke Katsura, Kazuko Seto, Hideki Kobayashi, Kimiko Kawano, Eisuke Tokuoka, Masato Furukawa, Seiya Harada, Shuji Yoshino, Junji Seto, Tetsuya Ikeda, Keiji Yamaguchi, Kazunori Murase, Yasuhiro Gotoh, Naoko Imuta, Junichiro Nishi, Tânia A Gomes, Lothar Beutin, Tetsuya Hayashi .  Defining the genome features of Escherichia albertii, an emerging enteropathogen closely related to Escherichia coli. .  Genome Biology and Evolution7 ( 12 ) 3170 - 3179   2015.12Reviewed

     More details

    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:Oxford Journals  

    Escherichia albertii is a recently recognized close relative of E. coli. This emerging enteropathogen possesses a type III secretion system (T3SS) encoded by the locus of enterocyte effacement (LEE), similar to enteropathogenic and enterohemorrhagic E. coli (EPEC and EHEC). Shiga toxin-producing strains have also been identified. The genomic features of E. albertii, particularly differences from other Escherichia species, have not yet been well clarified. Here, we sequenced the genome of 29 E. albertii strains (3 complete and 26 draft sequences) isolated from multiple sources and performed intra-species and intra-genus genomic comparisons. The sizes of the E. albertii genomes range from 4.5 Mb to 5.1 Mb, smaller than those of E. coli strains. Intra-species genomic comparisons identified five phylogroups of E. albertii. Intra-genus genomic comparison revealed that the possible core genome of E. albertii comprises 3,250 genes, whereas that of the genus Escherichia comprises 1,345 genes. Our analysis further revealed several unique or notable genetic features of E. albertii, including those responsible for known biochemical features and virulence factors and a possibly active second T3SS known as ETT2 (E. coli T3SS 2) that is inactivated in E. coli. Although this organism has been observed to be non-motile in vitro, genes for flagellar biosynthesis are fully conserved; chemotaxis-related genes have been selectively deleted. Based on these results, we have developed a nested PCR system to directly detect E. albertii. Our data define the genomic features of E. albertii and provide a valuable basis for future studies of this important emerging enteropathogen.

    DOI: 10.1093/gbe/evv211

  • Yoshitoshi Ogura, Shakhinur Islam Mondal, Md Rakibul Islam, Toshihiro Mako, Kokichi Arisawa, Keisuke Katsura, Tadasuke Ooka, Yasuhiro Gotoh, Kazunori Murase, Makoto Ohnishi, and Tetsuya Hayashi .  The Shiga toxin 2 production level in enterohemorrhagic Escherichia coli O157:H7 is correlated with the subtypes of toxin-encoding phage .  Scientific Reports5   16663   2015.11The Shiga toxin 2 production level in enterohemorrhagic Escherichia coli O157:H7 is correlated with the subtypes of toxin-encoding phageReviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)   Publisher:Nature Publishing Group  

  • Masahiro Kusumoto, Dai Fukamizu, Yoshitoshi Ogura, Eiji Yoshida, Fumiko Yamamoto, Taketoshi Iwata, Tadasuke Ooka, Masato Akiba, Tetsuya Hayashi .  The lineage-specific distribution of IS-excision enhancer in enterotoxigenic Escherichia coli isolated from swine. .  Applied and Environmental Microbiology80 ( 4 ) 1394 - 1402   2014.2The lineage-specific distribution of IS-excision enhancer in enterotoxigenic Escherichia coli isolated from swine.Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Atsushi Hinenoya, Kensuke Shima, Masahiro Asakura, Kazuhiko Nishimura, Teizo Tsukamoto, Tadasuke Ooka, Tetsuya Hayashi, T. Ramamurthy, S. Faruque, Shinji Yamasaki .  Molecular characterization of cytolethal distending toxin gene-positive Escherichia coli from healthy cattle and swine in Nara, Japan. .  BMC Microbiology14   97 - 97   2014Molecular characterization of cytolethal distending toxin gene-positive Escherichia coli from healthy cattle and swine in Nara, Japan.Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Koichi Murakami, Yoshiki Etoh, Eriko Tanaka, Sachiko Ichihara, Kazumi Horikawa, Kimiko Kawano, Tadasuke Ooka, Yoshiaki Kawamura, Kenichiro Ito .  Shiga toxin 2f-producing Escherichia albertii from a symptomatic human. .  Japanese Journal of Infectious Diseases67   204 - 208   2014Shiga toxin 2f-producing Escherichia albertii from a symptomatic human.Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Atsushi Iguchi, Y. Nagaya, E. Pradel, Tadasuke Ooka, Yoshitoshi Ogura, K.Katsura, Ken Kurokawa, Kenshiro Oshima, Masahira Hattori, Julian Parkhill, M. Sebaihia, S. Coulthurst, N. Gotoh, N.R. Thomson, J.J. Ewbank, Tetsuya Hayashi .  Genome evolution and plasticity of Serratia marcescens, an important multidrug resistant nosocomial pathogen. .  Genome Biology and Evolution6 ( 8 ) 2096 - 2110   2014Genome evolution and plasticity of Serratia marcescens, an important multidrug resistant nosocomial pathogen. Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Tadasuke Ooka, Eisuke Tokuoka, Masato Furukawa, Tetsuya Nagamura, Yoshitoshi Ogura, Kokichi Aisawa, Seiya Harada, Tetsuya Hayashi .  Human gastroenteritis outbreak associated with Escherichia albertii, Japan. .  Emerging Infectious Diseases19 ( 1 ) 144 - 146   2013Reviewed

     More details

    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3201/eid1901.120646

  • Tadasuke Ooka, Kazuko Seto, Kimiko Kawano, Hideki Kobayashi, Yoshiki Etoh, Sachiko Ichihara, Akiko Kaneko, Junko Isobe, Keiji Yamaguchi, Kazumi Horikawa, Tania Gomes, Annik Linden, Marjorie Bardiau, Jacques Mainil, Lothar Beutin, Yoshitoshi Ogura, Tetsuya Hayashi .  Clinical significance of Escherichia albertii. .  Emerging Infectious Diseases18 ( 3 ) 488 - 492   2012.3Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3201/eid1803.111401

  • Kazunori Murase, Tadasuke Ooka, Atsushi Iguchi, Yoshitoshi Ogura, Keisuke Nakayama, Md. Asadulghani, Md. R. Islam, Hirotaka Hiyoshi, Toshio Kodama, L. Beutin, Tetsuya Hayashi .  Hemolysin E- and enterohemolysin-derived hemolytic activity of O55/O157 strains and other Escherichia coli lineages. .  Microbiology158   746 - 758   2012.3Hemolysin E- and enterohemolysin-derived hemolytic activity of O55/O157 strains and other Escherichia coli lineages.Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Md. R. Islam, Yoshitoshi Ogura, Md. Asdulghani, Tadasuke Ooka, Kazunori Murase, Yasuhiro Gotoh, Tetsuya Hayashi .  A sensitive and simple plaque formation method for the Stx2 phage of Escherichia coli O157:H7, which does not form plaques in the standard plating procedure. .  Plasmid67 ( 3 ) 227 - 235   2012.1A sensitive and simple plaque formation method for the Stx2 phage of Escherichia coli O157:H7, which does not form plaques in the standard plating procedure.Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Naoko Saito, Ayumi Hida, Yuri Koide, Tadasuke Ooka, Yaeko Ichikawa, Jun Shimizu, Akitake Mukasa, Hirofumi Nakatomi, Shuji Hatakeyama, Tetsuya Hayashi, Shoji Tsuji .  Culture-negative brain abscess with Streptococcus intermedius infection with diagnosis established by direct nucleotide sequence analysis of the 16S ribosomal RNA gene. .  Internal Medicine51 ( 2 ) 211 - 216   2012.1Culture-negative brain abscess with Streptococcus intermedius infection with diagnosis established by direct nucleotide sequence analysis of the 16S ribosomal RNA gene.Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Atsushi Yokota, Satoru Fukiya, Tadasuke Ooka, Yoshitoshi Ogura, Tetsuya Hayashi, Satoshi Ishizuka .  Is bile acid a determinant of the gut microbiota on a high-fat diet? .  Gut Microbes3 ( 5 ) 455 - 459   2012Is bile acid a determinant of the gut microbiota on a high-fat diet?Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • K.B.M. Saiful Islam , Satoru Fukiya, Masahito Hagio, Nobuyuki Fujii, Satoshi Ishizuka, Tadasuke Ooka, Yoshitoshi Ogura, Tetsuya Hayashi, Atsushi Yokota .  Bile acid is a host factor that regulates the composition of the cecal microbiota in rats. .  Gastroenterology141 ( 5 ) 1773 - 1781   2011.10Bile acid is a host factor that regulates the composition of the cecal microbiota in rats.Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Jacques G. Mainil, Marjorie Bardiau, Tadasuke Ooka, Yoshitoshi Ogura, Kazunori Murase, Yoshiki Etoh, Sachiko Ichihara, Kazumi Horikawa, G. Buvens, D. Pierard, Takehiko Itoh, Tetsuya Hayashi .  IS621-based multiplex PCR printing method of O26 enterohaemorrhagic and enteropathogenic Escherichia coli isolated from humans and cattle. .  Journal of Applied Microbiology111   773 - 786   2011.9IS621-based multiplex PCR printing method of O26 enterohaemorrhagic and enteropathogenic Escherichia coli isolated from humans and cattle.Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Yohsuke Ogawa, Tadasuke Ooka, Fang Shi, Yoshitoshi Ogura, Keisuke Nakayama, Tetsuya Hayashi, Yoshihiko Shimoji .  The genome of Erysipelothrix rhusiopathiae, the causative agent of swine erysipelas, reveals new insights into the evolution of Firmicutes and the organism's intracellular adaptations. .  Journal of Bacteriology193 ( 12 ) 2959 - 2971   2011.6The genome of Erysipelothrix rhusiopathiae, the causative agent of swine erysipelas, reveals new insights into the evolution of Firmicutes and the organism's intracellular adaptations.Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Masahiro Kusumoto, Tadasuke Ooka, Yosuke Nishiya, Yoshitoshi Ogura, Takashi Saito, Yasuhiko Sekine, Taketoshi Iwata, Masato Akiba, Tetsuya Hayashi .  IS-excision enhancer removes transposable elements from bacterial genomes and induces various genomic deletions. .  Nature Communication2   152   2011IS-excision enhancer removes transposable elements from bacterial genomes and induces various genomic deletions.Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Tomomi Kuwahara, Yoshitoshi Ogura, Kenshiro Oshima, Ken Kurokawa, Tadasuke Ooka, Hideki Hirakawa, Takehiko Itoh, Haruyuki Nakayama-Imaohji, Minoru Ichimura, Kikuji Itoh, Chieko Ishifune, Yoichi Maekawa, Koji Yasutomo, Masahira Hattori, Tetsuya Hayashi .  The lifestyle of the segmented filamentous bacterium: a nonculturable gut-associated immunostimulating microbe inferred by whole-genome sequencing. .  DNA Research18   293 - 301   2011The lifestyle of the segmented filamentous bacterium: a nonculturable gut-associated immunostimulating microbe inferred by whole-genome sequencing.Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Hilo Yen, Tadasuke Ooka, Atsushi Iguchi, Tetsuya Hayashi, Nakaba Sugimoto, Toru Tobe .  NleC, a type III secretion protease, compromises NF-κB activation by targeting p65/RelA. .  PLoS Pathogen6 ( 12 ) e1001 231   2010.12NleC, a type III secretion protease, compromises NF-κB activation by targeting p65/RelA.Reviewed

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)  

  • Takahisa Yano, Kyaw Kyaw Moe, Kazuko Yamazaki, Tadasuke Ooka, Tetsuya Hayashi, Naoaki Misawa .  Identification of candidate pathogens of papillomatous digital dermatitis in dairy cattle from quantitative 16S rRNA clonal analysis. .  Veterinary Microbiology134   352 - 362   2010.7Identification of candidate pathogens of papillomatous digital dermatitis in dairy cattle from quantitative 16S rRNA clonal analysis.Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Yoshitoshi Ogura, Tadasuke Ooka, Atsushi Iguchi, Hidehiro Toh, Md. Asadulghani, Kenshiro Oshima, Toshio Kodama, Hiroyuki Abe, Keisuke Nakayama, Ken Kurokawa, Toru Tobe, Masahira Hattori, Tetsuya Hayashi .  Comparative genomics reveal the mechanism of the parallel evolution of O157 and non-O157 enterohemorrhagic Escherichia coli. .  Proceedings of the National Academy of Sciences106 ( 42 ) 17939 - 17944   2009.10Comparative genomics reveal the mechanism of the parallel evolution of O157 and non-O157 enterohemorrhagic Escherichia coli.Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Tadasuke Ooka, Jun Terajima, Masahiro Kusumoto, Atsushi Iguchi, Ken Kurokawa, Yoshitoshi Ogura, Asadulghani, Keisuke Nakayama, Kazunori Murase, Makoto Ohnishi, Sunao Iyoda, Haruo Watanabe, Tetsuya Hayashi .  Development of a multiplex PCR-based rapid typing method for enterohemorrhagic Escherichia coli O157 strains. .  Journal of Clinical Microbiology47 ( 9 ) 2888 - 2894   2009.9Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Tadasuke Ooka, Yoshitoshi Ogura, Asadulghani, Makoto Ohnishi, Keisuke Nakayama, Jun Terajima, Haruo Watanabe, Tetsuya Hayashi .  Inference of the impact of insertion sequence (IS) elements on bacterial genome diversification through analysis of small-size structural polymorphisms in Escherichia coli O157 genomes. .  Genome Research19   1809 - 1816   2009.6Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Md. Asadulghani, Yoshitoshi Ogura, Tadasuke Ooka, Takehiko Itoh, Akira Sawaguchi, Atsushi Iguchi, Keisuke Nakayama, Tetsuya Hayashi .  The defective prophage pool of Escherichia coli O157: prophage-prophage interactions potentiate horizontal transfer of virulence determinants. .  Plos Pathogens5 ( 5 ) e1000408   2009.5The defective prophage pool of Escherichia coli O157: prophage-prophage interactions potentiate horizontal transfer of virulence determinants.Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Atsushi Iguchi, N.R. Thomson, Yoshitoshi Ogura, D. Saunders, Tadasuke Ooka, I.R. Henderson, D. Harris, Asadulghani, Ken Kurokawa, P. Dean, B. Kenny, M.A. Quail, S. Thurston, G. Dougan, Tetsuya Hayashi, J. Parkhill, G. Frankel .  The complete genome sequence and comparative genome analysis of enteropathogenic E. coli O127:H6 strain E2348/69. .  Journal of Bacteriology191 ( 1 ) 347 - 354   2009.1The complete genome sequence and comparative genome analysis of enteropathogenic E. coli O127:H6 strain E2348/69.Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • E. Loukiadis, Rika Nobe, S. Herold, C. Tramuta, Yoshitoshi Ogura, Tadasuke Ooka, S. Morabito, M. Kerouredan, H. Brugere, H. Schmidt, Tetsuya Hayashi, E. Oswald .  Distribution, functional expression genetic organization of Cif, a phage-encoded type III-secreted effector from enteropathogenic and enterohaemorragic Escherichia coli. .  Journal of Bacteriology190 ( 1 ) 275 - 285   2008.1Distribution, functional expression genetic organization of Cif, a phage-encoded type III-secreted effector from enteropathogenic and enterohaemorragic Escherichia coli.Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • L. Bai, S. Schukker, A. Whale, A. Mousnier, O. Marches, L. Wang, Tadasuke Ooka, R. Heuschkel, J.B. Kaper, T.S.K. Gomes, J. Xu, A.D. Phillips, G. Frankel .  Enteropathogenic Escherichia coli (EPEC) O125:H6 triggers attaching and effacing lesions on human intestinal biopsies independently of Nck. .  Infection and Immunity76 ( 1 ) 361 - 368   2008.1Enteropathogenic Escherichia coli (EPEC) O125:H6 triggers attaching and effacing lesions on human intestinal biopsies independently of Nck.Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Tadasuke Ooka, Vieira MA, Yoshitoshi Ogura, Beutin L, Ragione RL, P. M. van Diemen, Stevens MP, Aktan I, Cawthraw S, Best A, Hernandes RT, Krause G, Gomes TA, Tetsuya Hayashi T, Frankel G .  Characterization of tccP2 carried by atypical enteropathogenic Escherichia coli. .  FEMS Microbiology Letters271   126 - 135   2007Characterization of tccP2 carried by atypical enteropathogenic Escherichia coli.Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Yoshitoshi Ogura, Tadasuke Ooka, A. Whale, J. Garmendia, L. Beutin, S. Tennant, G. Krause, S. Morabito, I. Chinen, Toru Tobe, Hiroyuki Abe, R. Tozzoli, A. Caprioli, M. Rivas, RR. Browne, Tetsuya Hayashi, G. Frankel .  TccP2 of O157:H7 and non-O157 Enterohemorrhagic Escherichia coli (EHEC): challenging the dogma of EHEC-induced actin polymerization. .  Infection and Immunity75   604 - 612   2007TccP2 of O157:H7 and non-O157 Enterohemorrhagic Escherichia coli (EHEC): challenging the dogma of EHEC-induced actin polymerization.Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • A. Whale, RT. Hernandes, Tadasuke Ooka, G. Krause, S. Schuller, J. Garmendia, L. Crowther, MA. Vieira, Yoshitoshi Ogura, AD. Phillips, L. Beutin, TA. Gomes, Tetsuya Hayashi, G. Frankel .  TccP2-mediated subversion of actin dynamics by EPEC 2 - a distinct evolutionary lineage of enteropathogenic Escherichia coli. .  Microbiology153   1743 - 1755   2007TccP2-mediated subversion of actin dynamics by EPEC 2 - a distinct evolutionary lineage of enteropathogenic Escherichia coli.Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Yoshitoshi Ogura, Tadasuke Ooka, Asadulghani, Jun Terajima, J-P. Nougayrede, Ken Kurokawa, Kousuke Tashiro, Toru Tobe, Keisuke Nakayama, Satoru Kuhara, E. Oswald, Haruo Watanabe, Tetsuya Hayashi .  Extensive genomic diversity and selective conservation of virulence-determinants in enterohaemorrhagic Escherichia coli strains of O157 and non-O157 serotypes. .  Genome Biology8 ( 7 ) R138   2007Extensive genomic diversity and selective conservation of virulence-determinants in enterohaemorrhagic Escherichia coli strains of O157 and non-O157 serotypes.Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

▼display all

Books

  • 細菌ゲノム解析の進歩

    大岡唯祐, 林哲也( Role: Joint author)

    日本臨床 増刊号 遺伝子診断学(第2版)-遺伝子診断の進歩とゲノム治療の展望-  2010.8 

     More details

    Language:Japanese Book type:Scholarly book

  • Genomic view on the evolution of enterohemorrhagic Escherichia coli.

    Tetsuya Hayashi, Tadasuke Ooka, Yoshitoshi Ogura, Asadulghani( Role: Joint author)

    Evolutionary Biology of Bacterial and Fungal Pathogens. AMS Press.  2007 

     More details

    Language:English Book type:Scholarly book

MISC

  • Escherichia albertii pathogenesis Reviewed

    Tania Gomes, Tadasuke Ooka, Rodrigo Hernandes, Denise Yamamoto, Tetsuya Hayashi

    EcoSal Plus   9 ( 1 )   2020.6

     More details

    Language:English   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)   Publisher:America Society for Microbiology  

    DOI: 10.1128/ecosalplus.ESP-0015-2019

  • 新興下痢症起因菌Escherichia albertiiの特徴

    大岡唯祐

    食品衛生研究   70 ( 10 )   19 - 35   2020.10

     More details

    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)   Publisher:公益財団法人日本食品衛生協会  

  • Emerging enteropathogen, Escherichia albertii

    Tadasuke Ooka

    Japanese Journal of Food Microbiology   34 ( 3 )   151 - 157   2017.9

     More details

    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)   Publisher:Japanese Society of Food Microbiology  

  • Bacterial genome analysis using Next generation sequencing technology: Current situation, problems, and future prospects.

    Tadasuke Ooka

    ANTIBIOTICS & CHEMOTHERAPY   33 ( 7 )   2017.6

     More details

    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)   Publisher:Iyaku(Medicine and Drug) Journa Co., Ltd.  

  • 鹿大・ベストティーチャー賞「わかりやすい講義」の秘密 Invited

    m3 Doctors LIFESTYLE   2023.11

  • ポリマイクロバイアル感染症としての牛趾皮膚炎の病態解明

    三澤尚明, 谷口喬子, 大岡唯祐, 後藤恭宏, 林 哲也

    家畜感染症学会誌   9 ( 4 )   139 - 145   2020.12

     More details

    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)   Publisher:家畜感染症学会  

  • 腸管出血性大腸菌O111の進化と病原性

    小椋義俊, 大岡唯祐, 林哲也

    神経内科・科学評論社   76 ( 2 )   155 - 163   2012.1

     More details

    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

  • ゲノム解析から見えてきた腸管出血性大腸菌の毒素及び病原因子の新知見

    小椋義俊, 大岡唯祐, 林哲也

    化学療法の領域   25 ( 5 )   767 - 777   2009

     More details

    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

  • 大腸菌O157のゲノム研究とその応用

    大岡唯祐, 小椋義俊, 林哲也

    臨床微生物迅速診断研究会誌(JARMAM)   16 ( 2 )   179 - 181   2005

     More details

    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

  • 腸管出血性大腸菌のゲノムの特徴

    大岡唯祐, 小椋義俊, 林哲也

    化学療法の領域   20 ( 9 )   1328 - 1333   2004.1

     More details

    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

▼display all

Presentations

  • 大岡唯祐、後藤恭宏、馬場洋一、柿澤広美、山本真実、新川奈緒美、 相星壮吾、伊藤武、林哲也、西順一郎   2018年に発生したSalmonella enterica serovar Oranienburg菌血症集積事例由来株の全国的蔓延  

    第44回日本食品微生物学会学術総会  2023.9  日本食品微生物学会

     More details

    Event date: 2023.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:堺市(大阪府)   Country:Japan  

  • 川合菜加、中西典子、西 順一郎、大岡唯祐   Acanthamoeba castellaniiにおけるEscherichia albertiiの細胞内生存能  

    第44回日本食品微生物学会学術総会  2023.9  日本食品微生物学会

     More details

    Event date: 2023.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:堺市(大阪府)   Country:Japan  

  • 大岡唯祐   Escherichia albertiiの病原性とゲノム特性について   Invited

    衛生微生物技術協議会第43回研究会  2023.7  衛生微生物技術協議会

     More details

    Event date: 2023.7

    Language:Japanese   Presentation type:Symposium, workshop panel (nominated)  

    Venue:じゅうろくプラザ(岐阜県岐阜市)   Country:Japan  

  • The identification and prevalence of the astA variants in Escherichia coli.  

    2023.3  Japanese Society for Bacteriology

     More details

    Event date: 2023.3

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  • Tadasuke Ooka, Naoko Imuta, Tetsuya Hayashi, and Junichiro Nishi   Prevalence and Divergence of intimin/Tir/TccP Variants in Escherichia albertii  

    The 95th Annual Meeting of Japanese Society for Bacteriology  2022.3  Japanese Society for Bacteriology

     More details

    Event date: 2022.3

    Language:Japanese   Presentation type:Oral presentation (general)  

  • 大岡唯祐   新興下痢症起因菌Escherichia albertiiによる最近の食中毒の状況と検査法   Invited

    令和2年度鹿児島県獣医公衆衛生講習会  鹿児島県獣医師会

     More details

    Event date: 2020.11

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Venue:マリンパレスかごしま  

  • 大岡唯祐、勢戸和子、小椋義俊、井口純、中村佳司、後藤恭宏、藺牟田直子、本田己喜子、池田徹也、杉谷和加奈、今野貴之、河野喜美子、工藤由起子、村上光一、林哲也、西順一郎   新興下痢症起因菌Escherichia albertiiのO抗原合成系の多様性と遺伝子タイピング法の開発  

    第23回腸管出血性大腸菌感染症研究会  腸管出血性大腸菌研究会

     More details

    Event date: 2019.11

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:愛媛県医師会館  

  • 大岡唯祐、藺牟田直子、後藤恭宏、小椋義俊、吉野修司、中山浩一郎、御供田睦代、林哲也、西順一郎   鹿児島市を中心としたSalmonella enterica serovar Oranienburgによる菌血症多発事例  

    第72回日本細菌学会九州支部総会  日本細菌学会九州支部

     More details

    Event date: 2019.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:熊本市国際交流会館  

  • 大岡唯祐   新興下痢症起因菌Escherichia albertiiのゲノム研究と検査法への応用   Invited

    令和元年度鹿児島県食品衛生監視機動班技術研修会  鹿児島県くらし保健福祉部生活衛生課

     More details

    Event date: 2019.6

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Venue:鹿児島県環境保健センター  

  • 大岡唯祐, 李謙一, 桂啓介, 伊豫田淳, 藺牟田直子, 林哲也, 大西真, 西順一郎   腸管出血性大腸菌O111用IS-printing systemの開発  

    第22回腸管出血性大腸菌感染症研究会  腸管出血性大腸菌感染症研究会

     More details

    Event date: 2018.11

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:国立感染症研究所、東京  

  • 大岡唯祐   新興下痢症起因菌Escherichia albertiiのゲノム研究と検査法への応用   Invited

    平成30年度地研近畿支部細菌部会研究会  地方衛生研究所全国協議会近畿支部

     More details

    Event date: 2018.11

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Venue:和歌山市役所  

  • 大岡唯祐、勢戸和子、小椋義俊、桂啓介、井口純、藺牟田直子、本田己喜子、池田徹也、杉谷和加奈、今野貴之、河野喜美子、村上光一、 西順一郎、林哲也   新興下痢症起因菌Escherichia albertiiのO抗原遺伝子タイピング法の開発  

    日本食品微生物学会第39回学術総会  日本食品微生物学会

     More details

    Event date: 2018.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:大阪  

  • 新興下痢症起因菌Escherichia albertiiの細菌学的特徴とゲノム特性   新興下痢症起因菌Escherichia albertiiの細菌学的特徴とゲノム特性   Invited

    第71回日本細菌学会九州支部総会 

     More details

    Event date: 2018.9

    Language:Japanese   Presentation type:Symposium, workshop panel (nominated)  

    Venue:北九州市  

  • Tadasuke Ooka, Islam Md. Rakibul, Shoko Ochiai, Yoshitoshi Ogura, Kazuko Seto, Junko Isobe, Tetsuya Ikeda, Junji Seto, Yasuhiro Gotoh, Junichiro Nishi, Tetsuya Hayashi   Genomic comparison of Stx2f phages from Escherichia coli and Escherichia albertii   International conference

    10th International Symposium on Shiga Toxin (Verocytotoxin) Producing Escherichia Coli Infections 

     More details

    Event date: 2018.5

    Language:English   Presentation type:Poster presentation  

    Venue:Congress Centre (Florence, Italy)  

  • 大岡唯祐、村上光一、勢戸和子、小椋義俊、藺牟田直子、吉家清貴、林哲也、西順一郎   PCRによる新興下痢症起因菌Escherichia albertiiの O抗原タイピング法の開発  

    第91回日本細菌学会総会  日本細菌学会

     More details

    Event date: 2018.3

    Language:Japanese   Presentation type:Poster presentation  

    Venue:福岡国際会議場  

  • 大岡唯祐、藺牟田直子、郡山豊泰、古城剛、宮之原弘晃、吉家清貴、西順一郎   鹿児島県における下痢症患児分離株からのEscherichia albertiiの同定およびその特徴  

    第20回腸管出血性大腸菌感染症研究会  腸管出血性大腸菌感染症研究会

     More details

    Event date: 2016.11

    Language:English   Presentation type:Oral presentation (general)  

    Venue:富山県民共生センターサンフォルテ(富山市)  

  • 大岡唯祐, 藺牟田直子, 吉家清貴, 西順一郎   新興ヒト下痢症起因菌Escherichia albertiiの家畜等からの感染リスク調査  

    第90回日本感染症学会  日本感染症学会

     More details

    Event date: 2016.4

    Language:Japanese   Presentation type:Poster presentation  

    Venue:仙台国際センター(宮城)  

  • The genetic diversity of the O-antigen gene cluster in E. albertii, an emerging enteropathogen  

    The 89th Annual Meeting of Japanese Society for Bacteriology  Japanese Society for Bacteriology

     More details

    Event date: 2016.3

    Language:Japanese   Presentation type:Poster presentation  

  • 藺牟田直子、大岡唯祐、吉家清貴、西順一郎   下痢症患児由来大腸菌における腸管凝集性大腸菌EAECとESBL産生大腸菌の動向  

    第89回日本細菌学会総会  日本細菌学会

     More details

    Event date: 2016.3

    Language:Japanese   Presentation type:Poster presentation  

    Venue:大阪  

  • 吉家清貴、大岡唯祐、藺牟田直子、西順一郎   生活環境空気中の浮遊薬剤耐性菌  

    第89回日本細菌学会総会  日本細菌学会

     More details

    Event date: 2016.3

    Language:Japanese   Presentation type:Poster presentation  

    Venue:大阪  

  • 後藤恭宏、小椋義俊、大岡唯祐、矢野貴久、大島健志朗、服部正平、三澤尚明、林哲也   Treponema phagedenisのゲノム進化と適応  

    第89回日本細菌学会総会  日本細菌学会

     More details

    Event date: 2016.3

    Language:Japanese   Presentation type:Poster presentation  

    Venue:大阪  

  • 西田留梨子、村瀬一典、後藤恭宏、大岡唯祐、中島遥子、片平雄之、伊豫田淳、大西真、小椋義俊、林哲也   腸管出血性大腸菌O121:H19の比較ゲノム解析  

    第89回日本細菌学会総会  日本細菌学会

     More details

    Event date: 2016.3

    Language:Japanese   Presentation type:Poster presentation  

    Venue:大阪  

  • 中島遥子、西田留梨子、大岡唯祐、大西真、吉野修司、片平雄之、後藤恭宏、林哲也、小椋義俊   腸管出血性大腸菌出現プロセスの解明を目的としたウシ/ヒト由来大腸菌の大規模比較解析  

    第89回日本細菌学会総会  日本細菌学会

     More details

    Event date: 2016.3

    Language:Japanese   Presentation type:Poster presentation  

    Venue:大阪  

  • Tadasuke Ooka   Genomic diversity and evolutionary insights of Escherichia albertii, an emerging enteropathogen closely related to Escherichia coli   International conference

    SMBE Satellite Workshop on Genome Evolution in Pathogen Transmission and Disease 

     More details

    Event date: 2016.2

    Language:English   Presentation type:Poster presentation  

    Venue:Shiga Lake Hotel, Shiga Kogen, Japan  

  • 大岡唯祐、勢戸和子、磯部順子、瀬戸順次、池田徹也、 藺牟田直子、西順一郎   志賀毒素サブタイプStx2f転換ファージの構造比較及び種間伝播に関する解析  

    第85回感染症学会西日本地方会  日本感染症学会

     More details

    Event date: 2015.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:奈良  

  • Monica A. M. Vieira, Bruna G. Garcia, Tadasuke Ooka, Suely C. Sampaio, Tetsuya Hayashi, Tania A. T. Gomes   Distribution of the pilS gene encoding the pilin of a type IV pilus among typical enteropathogenic Escherichia coli strains presenting localized or localized and aggregative adherence patterns   International conference

    VTEC2015 

     More details

    Event date: 2015.9

    Language:English   Presentation type:Poster presentation  

    Venue:ボストン(アメリカ)  

  • 大岡唯祐、勢戸和子、磯部順子、瀬戸順次、池田徹也、 藺牟田直子、小椋義俊、西順一郎、林哲也   EHECおよびE. albertiiにおけるStx2f転換ファージの解析  

    第19回腸管出血性大腸菌感染症研究会  腸管出血性大腸菌感染症研究会

     More details

    Event date: 2015.7

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:東京  

  • 大岡唯祐、勢戸和子   新興下痢原性病原菌Escherichia albertiiのゲノム解析と疫学ツールの開発  

    第89回日本感染症学会総会・学術講演会  第89回日本感染症学会総会・学術講演会

     More details

    Event date: 2015.4

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:京都  

    国内学会

  • 緒方喜久代,大岡唯祐,成松浩志,林哲也   湧き水を原因としたEscherichia albertiiによる食中毒  

    第87回日本細菌学会総会(ワークショップ)  第87回日本細菌学会総会(ワークショップ)

     More details

    Event date: 2015.3

    Language:Japanese  

    Venue:東京  

    国内学会

  • Naoko Imuta, Tadasuke Ooka, Kazuko Seto, Kiyotaka Yoshiie, Yoshitoshi Ogura, Tetsuya Hayashi, Junichiro Nishi   Genetic heterogenity of AggR-positive enteroaggregative Escherichia coli (EAEC)  

    第88回日本細菌学会総会  第88回日本細菌学会総会

     More details

    Event date: 2015.3

    Language:Japanese  

    Venue:岐阜  

    国内学会

  • 大岡唯祐、勢戸和子、後藤恭宏、小椋義俊、林哲也   新規下痢原性病原菌Escherichia albertiiのゲノム特性  

    第88回日本細菌学会総会  第88回日本細菌学会総会

     More details

    Event date: 2015.3

    Language:Japanese  

    Venue:岐阜  

    国内学会

  • 藺牟田直子,大岡唯祐,勢戸和子,徳田浩一, 吉家清貴,小椋義俊,林 哲也,西 順一郎   腸管凝集性大腸菌(EAEC)の遺伝的多様性  

    第67回日本細菌学会九州支部総会  第67回日本細菌学会九州支部総会

     More details

    Event date: 2014.9

    Language:Japanese  

    Venue:鹿児島  

    国内学会

  • 大岡唯祐,勢戸和子,小野英俊,河野喜美子,小林秀樹,吉野修司,瀬戸順次,山口敬治,古川真斗,徳岡英亮,井口純,藺牟田直子,原田誠也,西順一郎,桂啓介,小椋義俊,林哲也   新興病原体Escherichia albertiiのゲノムおよび疫学解析  

    第35回日本食品微生物学会総会  第35回日本食品微生物学会総会

     More details

    Event date: 2014.9

    Language:Japanese  

    Venue:大阪  

    国内学会

  • 大岡唯祐、林哲也   人獣共通新興病原体Escherichia albertiiのゲノムの特徴と診断疫学マーカーの開発  

    第157回日本獣医学会学術集会 微生物学分科会企画シンポジウム  第157回日本獣医学会学術集会 微生物学分科会企画シンポジウム

     More details

    Event date: 2014.9

    Language:Japanese  

    Venue:北海道  

    国内学会

  • 緒方喜久代,大岡唯祐,成松浩志,林哲也   湧き水を原因としたEscherichia albertiiによる食中毒  

    第87回日本細菌学会総会(ワークショップ)  第87回日本細菌学会総会(ワークショップ)

     More details

    Event date: 2014.3

    Language:Japanese  

    Venue:東京  

    国内学会

  • 藺牟田直子, 大岡唯祐, 吉家清貴, 小椋義俊, 林哲也, 西順一郎   ESBL産生腸管凝集性大腸菌(EAEC)の分子疫学解析  

    第87回日本細菌学会総会  第87回日本細菌学会総会

     More details

    Event date: 2014.3

    Language:Japanese  

    Venue:東京  

    国内学会

  • 原田誠也, 大岡唯祐, 林哲也   熊本県で発生したEscherichia albertii食中毒2事例について  

    第87回日本細菌学会総会(ワークショップ)  第87回日本細菌学会総会(ワークショップ)

     More details

    Event date: 2014.3

    Language:Japanese  

    Venue:東京  

    国内学会

  • Arzuba Akter, Tadasuke Ooka, Seigo Yamamoto, Keisuke Katsura, Yoshitoshi Ogura, Tetsuya Hayashi   Comparative genome analysis of Spotted fever group Rickettsia in Japan.  

    第8回日本ゲノム微生物学会年会  第8回日本ゲノム微生物学会年会

     More details

    Event date: 2014.3

    Language:Japanese  

    Venue:東京  

    国内学会

  • Arzuba Akter, Ooka T, Yamamoto S, Katsura K, Ogura Y, and Hayashi T   Comparative genome analysis of Spotted fever group Rickettsia in Japan ; R. japonica and R. heilongjiangensis.  

    第8回日本ゲノム微生物学会年会  第8回日本ゲノム微生物学会年会

     More details

    Event date: 2014.3

    Language:Japanese  

    Venue:東京  

    国内学会

  • 大岡唯祐   腸管出血性大腸菌O157の型別ツールIS-printing system:開発と実用化までの道のり  

    第87回日本細菌学会総会(ワークショップ)  第87回日本細菌学会総会(ワークショップ)

     More details

    Event date: 2014.3

    Language:Japanese  

    Venue:東京  

    国内学会

  • 古川真斗,福司山郁恵,奥田将之,松尾繁,郷博臣,大岡唯祐,林哲也,原田誠也   熊本県で発生したEscherichia albertiiによる食中毒事例について  

    第34回日本食品微生物学会学術総会  第34回日本食品微生物学会学術総会

     More details

    Event date: 2013.10

    Language:Japanese  

    Venue:東京  

    国内学会

  • 大岡唯祐, 桂啓介, 小椋義俊, Arzuba Akter, 北野智一, 後藤恭宏, 山本正悟, 林哲也   日本紅斑熱リケッチアRickettsia japonica及び紅斑熱群リケッチアR. heilongjiangensisのゲノム及びゲノム比較解析  

    第66回日本細菌学会九州支部総会  第66回日本細菌学会九州支部総会

     More details

    Event date: 2013.9

    Language:Japanese  

    Venue:長崎  

    国内学会

  • Ooka T, Seto K, Kawano K, Kobayashi H, Etoh Y, Ichihara S, Kaneko N, Isobe J, Yamaguchi K, Horikawa K, Gomes TA, Linden A, Bardiau M, Mainil JG, Beutin L, Ogura Y, Hayashi T   Significant prevalence of Escherichia albertii among the strains identified as enteropathogenic and enterohemorrhagic E. coli and the presence of Shiga toxin-producing E. albertii strains.   International conference

    VTEC 2012: 8th International Symposium on Shiga Toxin (Verocytotoxin) producing Escherichia coli infections  VTEC 2012: 8th International Symposium on Shiga Toxin (Verocytotoxin) producing Escherichia coli infections

     More details

    Event date: 2012.5

    Language:English  

    Venue:Amsterdam  

    国際学会

  • 大岡唯祐, 勢戸和子, 磯部順子, 山口敬治, 瀬戸順次, 小椋義俊, 林哲也   志賀毒素バリアントStx2fの伝播様式の解析  

    第85回日本細菌学会総会  第85回日本細菌学会総会

     More details

    Event date: 2012.3

    Language:Japanese  

    Venue:長崎  

    国内学会

  • 大岡唯祐,小椋義俊,中山恵介,小林秀樹,林哲也   腸管出血性大腸菌(EHEC)及び腸管病原性大腸菌(EPEC)における3型分泌系(T3SS)の進化  

    第83回日本細菌学会総会  第83回日本細菌学会総会

     More details

    Event date: 2010.3

    Language:Japanese  

    Venue:神奈川  

    国内学会

  • 大岡唯祐   新規遺伝子解析法について.IS-printing Systemによる遺伝子解析  

    厚生労働科研「食品由来感染症調査における分子疫学手法に関する研究」班研修会  厚生労働科研「食品由来感染症調査における分子疫学手法に関する研究」班研修会

     More details

    Event date: 2010.2

    Language:Japanese  

    Venue:熊本  

    その他

  • 大岡唯祐,小椋義俊,井口純,Asadulghani,中山恵介,小林秀樹,寺嶋淳,渡邉治雄,林哲也   腸管出血性大腸菌(EHEC)及び腸管病原性大腸菌(EPEC)におけるLEE領域の多様性解析  

    第82回日本細菌学会総会  第82回日本細菌学会総会

     More details

    Event date: 2009.3

    Language:Japanese  

    Venue:愛知  

    国内学会

  • 大岡唯祐,小椋義俊,中山恵介,寺嶋淳,渡辺治雄,林哲也   腸管出血性大腸菌O157の小規模ゲノム構造多型に関する詳細な解析  

    第81回日本細菌学会総会  第81回日本細菌学会総会

     More details

    Event date: 2008.3

    Language:Japanese  

    Venue:京都  

    国内学会

  • 大岡唯祐,小椋義俊,井口純,Asadulghani,中山恵介,戸邉亨,寺嶋淳,渡邊治雄,林哲也   non-O157 EHECゲノムにおけるIS分布の解析  

    第80回日本細菌学会総会  第80回日本細菌学会総会

     More details

    Event date: 2007.3

    Language:Japanese  

    Venue:大阪  

    国内学会

  • Ooka T, Ogura Y, Nakayama K, Kurokawa K, Ohnishi M, Terajima J, Watanabe H, Hayashi T   The mechanism of genomic diversification in Enterohemorrhagic E. coli O157:H7.   International conference

    VTEC 2006 Melbourne (6th International Symposium on Shiga Toxin (Verocytotoxin)-Producing Escherichia coli Infections)  VTEC 2006 Melbourne (6th International Symposium on Shiga Toxin (Verocytotoxin)-Producing Escherichia coli Infections)

     More details

    Event date: 2006.10

    Language:English  

    Venue:Melbourne  

    国際学会

  • 大岡唯祐,小椋義俊,中山恵介,黒川顕,寺嶋淳,渡辺治雄,林哲也   IS分布を利用したマルチプレックスPCRによる迅速なO157菌株識別システムの開発  

    第79回日本細菌学会総会  第79回日本細菌学会総会

     More details

    Event date: 2006.3

    Language:Japanese  

    Venue:石川  

    国内学会

  • 大岡唯祐   九州地区における食品由来感染症の拡大防止・予防に関する取組み.O157新規遺伝子解析法IS-printing Systemに関する研修  

    厚生労働科研「広域における食品由来感染症を迅速に探知するために必要な情報に関する研究」班研修会  厚生労働科研「広域における食品由来感染症を迅速に探知するために必要な情報に関する研究」班研修会

     More details

    Event date: 2006.1

    Language:Japanese  

    Venue:宮崎  

    その他

  • 大岡唯祐   大腸菌O157のゲノム研究とその応用  

    第18回臨床微生物迅速診断研究会総会  第18回臨床微生物迅速診断研究会総会

     More details

    Event date: 2005.6

    Language:Japanese  

    Venue:長野  

    国内学会

  • 大岡唯祐,小椋義俊,大西真,中山恵介,森本拓也,林哲也   O157株間のゲノム構造多型に関する網羅的な解析  

    第78回日本細菌学会総会  第78回日本細菌学会総会

     More details

    Event date: 2005.4

    Language:Japanese  

    Venue:東京  

    国内学会

  • 大岡唯祐,大西真,寺嶋淳,小椋義俊,中山恵介,渡辺治雄,林哲也   マルチプレックスPCRを用いた迅速なO157菌株識別システムの開発  

    第77回日本細菌学会総会  第77回日本細菌学会総会

     More details

    Event date: 2004.4

    Language:Japanese  

    Venue:大阪  

    国内学会

  • Ooka T, Seto K, Kawano K, Kobayashi H, Ichihara S, Etoh Y, Horikawa K, Ogura Y, Hayashi T   Phylogenetic and intimin-subtype analysis of eae -positive E. coli strains.   International conference

    US-Japan Cooperative Medical Science Program, 45th Annual Joint Panel Meeting on Cholera and Other Bacterial Enteric Infections Panel  US-Japan Cooperative Medical Science Program, 45th Annual Joint Panel Meeting on Cholera and Other Bacterial Enteric Infections Panel

     More details

    Language:English  

    Venue:Kyoto  

    国際学会

  • 小野英俊, 大岡唯祐, 林哲也   鶏、豚及び牛におけるEsherichia albertii保菌調査  

    平成25年度獣医学術九州地区学会  平成25年度獣医学術九州地区学会

     More details

    Language:Japanese  

    Venue:大分  

    国内学会

  • 有村 尚子, 川村 英樹, 稲森 彩, 茂見 茜里, 藺牟田 直子, 西 順一郎, 福山 竜子, 舞木 公子, 大岡 唯祐   2剤耐性アシネトバクター検出を契機に全病院的な経管栄養・ティーサーバー管理の改善を図った事例  

    日本環境感染学会総会プログラム・抄録集  2023.6  (一社)日本環境感染学会

     More details

    Language:Japanese  

▼display all

Intellectual Property

  • 微生物の識別方法、及び該方法に使用するプライマー並びに識別キット

    大岡 唯祐、林 哲也

     More details

    Applicant:東洋紡株式会社、国立大学法人宮崎大学

    Announcement no:2008-005837  Date announced:2008.1

    Patent/Registration no:5110423  Date registered:2012.10 

    Country of applicant:Domestic  

Awards

  • 令和4年度鹿児島大学ベストティーチャー賞

    2023.8   鹿児島大学  

     More details

    Country:Japan

  • 令和4年度 鹿児島大学医学部医学科 最優秀ベストティーチャー賞

    2023.5   鹿児島大学医学部医学科  

     More details

    Country:Japan

Research Projects

  • 新興下痢症起因菌Escherichia albertiiの集団感染および水環境からの感染リスク解析

    Grant number:24K13415  2024.4 - 2027.3

    日本学術振興会  科学研究費助成事業(学術研究助成基金助成金)  基盤研究(C)(一般)

      More details

    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\4550000 ( Direct Cost: \3500000 、 Indirect Cost:\1050000 )

  • Research on development of testing methods for diarrheagenic Escherichia coli causing foodborne infections, and promotion of preventive measures against the infections

    Grant number:24KA1002  2024.4 - 2027.3

      More details

    Authorship:Coinvestigator(s)  Grant type:Competitive

    Grant amount:\3900000 ( Direct Cost: \3000000 、 Indirect Cost:\900000 )

  • 新たな人獣共通感染症の発生に備えた事前リスク評価

    Grant number:21455165  2021.4

    農林水産省  安全な農畜水産物安定供給のための包括的レギュラトリーサイエンス研究推進委託事業 

    大岡唯祐

      More details

    Authorship:Coinvestigator(s)  Grant type:Competitive

    Grant amount:\6000000 ( Direct Cost: \4200000 、 Indirect Cost:\1800000 )

  • 食中毒原因細菌の検査法の整備のための研究(食品の安全確保推進研究事業)

    Grant number:21KA1006  2021.4 - 2024.3

    厚生労働省  科学技術振興調整費  令和3年度厚生労働科学研究費補助金

    大岡唯祐

      More details

    Authorship:Coinvestigator(s)  Grant type:Competitive

    Grant amount:\9379000 ( Direct Cost: \7217000 、 Indirect Cost:\2162000 )

  • Escherichia albertiiのアメーバへの感染・増殖機構の解明

    Grant number:20K07498  2020.4 - 2023.3

    日本学術振興会  科学研究費補助金  基盤研究(C)

    大岡 唯祐

      More details

    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\4420000 ( Direct Cost: \3400000 、 Indirect Cost:\1020000 )

  • 食品中の食中毒細菌の制御法の確立のための研究(食品の安全確保推進研究事業)

    Grant number:H30-食品-一般-001  2018.4 - 2021.3

    厚生労働省  科学技術振興調整費 

      More details

    Authorship:Coinvestigator(s)  Grant type:Competitive

    Grant amount:\8239000 ( Direct Cost: \6338000 、 Indirect Cost:\1901000 )

  • 食品由来が疑われる有症事案に係る調査(食中毒調査)の迅速化・高度化に関する研究(食品の安全確保推進研究事業)

    Grant number:H29-食品-一般-001  2017.4 - 2020.3

    厚生労働省  科学技術振興調整費 

    大岡唯祐

      More details

    Authorship:Coinvestigator(s)  Grant type:Competitive

    Grant amount:\5676000 ( Direct Cost: \4154000 、 Indirect Cost:\1522000 )

  • 新興病原菌Escherichia albertiiの種特性と病原機構の解明(代表)

    Grant number:16K08781  2016.4 - 2019.3

    科学研究費補助金  基盤研究(C)

    大岡唯祐

      More details

    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\4810000 ( Direct Cost: \3700000 、 Indirect Cost:\1110000 )

  • 新興病原体Escherichia albertiiの疫学および病原性の解明(代表)

    Grant number:25460539  2013.4 - 2016.3

    科学研究費補助金  基盤研究(C)

      More details

    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\3900000 ( Direct Cost: \2730000 、 Indirect Cost:\1170000 )

  • 新規病原菌種Escherichia albertii:ゲノム情報に基づく診断疫学マーカーの確立とヒト及び動物における腸内常在性の解明

    2012.4 - 2014.3

    その他機関  公益財団法人黒住医学研究振興財団 

      More details

    Authorship:Principal investigator  Grant type:Competitive

  • 新規下痢原性病原菌Escherichia albertiiのゲノム及び病原性解析(代表)

    Grant number:23790480  2011.4 - 2013.3

    科学研究費補助金  若手研究(B)

      More details

    Grant type:Competitive

  • 腸管出血性大腸菌の新規DNA修復機構の同定と機能解析(代表)

    Grant number:20790338  2008.4 - 2010.3

    科学研究費補助金  若手研究(B)

      More details

    Authorship:Principal investigator  Grant type:Competitive

  • 小児腸管内バイオフィルム形成大腸菌が薬剤耐性遺伝子の水平伝播を促進する機構の解明

    Grant number:20K08161  2020.4 - 2023.3

    文部科学省  科学研究費助成事業  基盤研究(C)

    西 順一郎, 藺牟田 直子, 児玉 祐一, 大岡 唯祐

      More details

    Authorship:Coinvestigator(s)  Grant type:Competitive

    Grant amount:\300000 ( Direct Cost: \3400000 、 Indirect Cost:\1020000 )

  • 新興下痢起因菌Escherichia albertiiのヒトに対する感染リスクの解析と病原株鑑別法の開発

    2019.2

    民間財団等  公益信託 児玉記念基礎医学助成基金平成30年度助成金  

      More details

    Grant type:Competitive

  • Escherichia albertiiの性状に関する解析

    2017.2

    地方自治体  国内共同研究 

  • 新興下痢起因菌Escherichia albertiiのヒトに対する感染リスクの解析と病原株鑑別法の開発

    2016.8 - 2017.8

    民間財団等  公益信託 児玉記念基礎医学助成基金平成28年度助成金 

      More details

    Grant type:Competitive

  • 大腸菌およびその近縁菌種のゲノム比較と病原機構に関する研究

    2016.4 - 2023.3

    地方自治体  国内共同研究 

      More details

    腸管出血性大腸菌(EHEC)と腸管病原性大腸菌(EPEC)、腸管凝集性大腸菌(EAEC)などの病原性大腸菌とEscherichia albertiiなどの大腸菌近縁菌種について、病原性関連因子を中心として既知の腸管病原菌とのゲノム比較解析を行う。さらに、個々の菌が持つ病原因子とその病原機構への関わりを調べることにより、各菌の病原性の全体像を明らかにする。

  • 大腸菌関連菌種のゲノム比較と病原機構に関する研究

    2015.10 - 2020.9

    地方自治体  国内共同研究 

      More details

    大腸菌関連菌種についてゲノム比較解析および病原性解析を行い、病原因子のレパートリーを含むゲノム進化とその病原機構を明らかにする。

  • 腸管病原性大腸菌およびEscherichia albertiiに関するゲノムおよび病原性解析

    2012.6

    国際共同研究 

  • 新世代DNA塩基配列決定技術を用いた大腸菌pan-genomeの解明(分担)

    2008.4 - 2011.3

    科学研究費補助金  基盤研究(B)

  • 腸管の粘膜表層に常在する細菌群のゲノム解析(分担)

    2006.4 - 2008.3

    科学研究費補助金  基盤研究(B)

  • 腸管出血性大腸菌を中心とした腸管感染菌の病原性ゲノム基盤の解明と臨床応用(分担)

    2005.4 - 2009.3

    科学研究費補助金  特定領域研究

  • 全ゲノム情報に基づいた恙虫病病原体の病原性解析とその臨床応用に関する研究(分担)

    2005.4 - 2007.3

    地方自治体  宮崎県戦略的地域科学技術振興事業補助金 

      More details

    Grant type:Competitive

▼display all

 

Teaching Experience

  • Microbiology

    2016
    Institution:Kagoshima University

     More details

    Level:Undergraduate (specialized)  Country:Japan

  • 自主研究(選択)

    2022
    Institution:鹿児島大学

  • 人間と微生物

    2019
    Institution:鹿児島大学

     More details

    Level:Undergraduate (specialized)  Country:Japan

  • 自主研究(必修)

    2019
    Institution:鹿児島大学

     More details

    Country:Japan

  • 感染と生体防御

    2017
    Institution:鹿児島大学

     More details

    Level:Postgraduate  Country:Japan

  • 微生物学特講

    2020
    Institution:鹿児島大学

     More details

    Level:Postgraduate  Country:Japan

  • 感染症

    2016
    Institution:鹿児島大学

     More details

    Level:Undergraduate (specialized)  Country:Japan

  • 生命科学

    2020
    Institution:鹿児島大学

     More details

    Level:Undergraduate (specialized)  Country:Japan

  • 微生物学

    2004
    -
    2014
    Institution:宮崎大学医学部

     More details

    Level:Undergraduate (specialized)  Country:Japan

  • 微生物学

    2019
    Institution:たちばな医療専門学校

  • 感染と免疫

    Institution:宮崎学園短期大学

  • 微生物学

  • 微生物学

    2023.4

     More details

    Country:Japan

  • 微生物学

     More details

    Country:Japan

▼display all

 

Social Activities

  • 第3回下痢原性大腸菌等遺伝子検査法講習会

    Role(s): Lecturer

    宮崎大学  2024.8

  • 進路懇談会

    Role(s): Lecturer

    鳳凰高等学校  2024.7

  • 第2回下痢原性大腸菌等遺伝子検査法講習会

    Role(s): Lecturer

    日本食品微生物学会  2024.7

  • Nodal Person for FABA in Japan

    Role(s): Organizing member

    The Federation of Asian Biotech Associations (FABA)  2024.4

  • 進路懇談会

    Role(s): Lecturer

    学校法人希望が丘学園 鳳凰高等学校  生徒との進路懇談会  2023.11

  • 第1回下痢原性大腸菌等遺伝子検査法講習会

    Role(s): Lecturer

    宮崎大学  2023.8

  • Escherichia albertiiの病原性とゲノム特性について

    Role(s): Lecturer

    衛生微生物技術協議会  衛生微生物技術協議会第43回研究会  2023.7

  • 令和2年度鹿児島県獣医公衆衛生講習会

    Role(s): Lecturer

    (公社)鹿児島県獣医師会  マリンパレスかごしま(マリンホール)  2020.11

     More details

    Audience: Scientific, Governmental agency

    Type:Lecture

  • 令和元年度鹿児島県食品衛生監視機動班技術研修会

    Role(s): Lecturer

    鹿児島県くらし保健福祉部生活衛生課  鹿児島県環境保健センター  2019.6

     More details

    Audience: Scientific, Governmental agency

    Type:Lecture

  • 平成30年度地研近畿支部細菌部会研究会

    Role(s): Lecturer

    地方衛生研究所全国協議会近畿支部  和歌山市役所  2018.11

     More details

    Audience: Researchesrs, Governmental agency

    Type:Lecture

  • 平成30年度第6回環保研セミナー

    Role(s): Lecturer

    神戸市環境保健研究所  神戸市環境保健研究所  2018.9

     More details

    Audience: Researchesrs, Governmental agency

    Type:Seminar, workshop

  • たちばな医療専門学校

    Role(s): Lecturer

    2016.4

     More details

    Audience: General

    Type:Other

▼display all

Media Coverage

  • 「先生と学生、机を並べて研究」双方のメリットは Internet

    m3.com  m3.comDoctors LIFESTYLE  https://www.m3.com/lifestyle/1174110  2023.11

     More details

    Author:Other 

  • 鹿大・ベストティーチャー賞「わかりやすい講義」の秘密 Internet

    m3.com  m3.comDoctors LIFESTYLE  https://www.m3.com/lifestyle/1174109  2023.11

     More details

    Author:Other