日本獣医学会

2015.10

2. Koudatsu, S., Masatani, T., Konishi, R., Asada, M., Hakimi, H., Kurokawa, Y., Tomioku, K., Kaneko, O., Fujita, A. .  Glycosphingolipid GM3 is localized in both exoplasmic and cytoplasmic leaflets of Plasmodium falciparum malaria parasite plasma membrane. .  Sci. Rep.11 ( 1 ) 14890   2021.7Glycosphingolipid GM3 is localized in both exoplasmic and cytoplasmic leaflets of Plasmodium falciparum malaria parasite plasma membrane.Reviewed

3. Kurokawa, Y., Konishi, R., Yoshida, A., Tomioku, K., Tanabe, K., Fujita, A. .  The distribution of phosphatidylinositol 4,5-bisphosphate in the budding yeast plasma membrane. .  Histochem. Cell Biol.156 ( 2 ) 109 - 121   2021.5The distribution of phosphatidylinositol 4,5-bisphosphate in the budding yeast plasma membrane.Reviewed

Rikako Konishi, Yuna Kurokawa, Kanna Tomioku, Tatsunori Masatani, Xuenan Xuan, Akikazu Fujita .  Raft microdomain localized in the luminal leaflet of inner membrane complex of living Toxoplasma gondii .  Eur. J. Cell Biol.100   151149   2021.1Raft microdomain localized in the luminal leaflet of inner membrane complex of living Toxoplasma gondiiReviewed

Microautophagy in the yeast vacuole depends on the activities of phosphatidylinositol 4-kinases, Stt4p and Pik1p .  Biochim. Biophys. Acta. Biomembrane.1862   183416   2020.7Microautophagy in the yeast vacuole depends on the activities of phosphatidylinositol 4-kinases, Stt4p and Pik1pReviewed

1. Kurokawa, Y., Masatani, T., Konishi R, Tomioku, K., Xuan, X., Fujita, A. .  Nanoscale analysis reveals no domain formation of glycosylphosphatidylinositol-anchored protein SAG1 in the plasma membrane of living Toxoplasma gondii. .  Histochem. Cell Biol.   2019.9Nanoscale analysis reveals no domain formation of glycosylphosphatidylinositol-anchored protein SAG1 in the plasma membrane of living Toxoplasma gondii.Reviewed

3. Kurokawa, Y., Konishi, R., Yoshida, A., Fujii, E., Tomioku, K., Futagami, T., Tamaki, H., Tanabe, K., Fujita, A. .  Essential and distinct roles of phosphatidylinositol 4-kinases, Pik1p and Stt4p, in yeast autophagy. .  Biochim. Biophys. Acta. Mol. Cell Biol. Lipids. 1864   1214 - 1225   2019.9Essential and distinct roles of phosphatidylinositol 4-kinases, Pik1p and Stt4p, in yeast autophagy.Reviewed

Kurokawa Y, Konishi R, Yoshida A, Tomioku K, Futagami T, Tamaki H, Tanabe K, Fujita A .  Essential and distinct roles of phosphatidylinositol 4-kinases, Pik1p and Stt4p, in yeast autophagy. .  Biochimica et biophysica acta. Molecular and cell biology of lipids1864 ( 9 ) 1214 - 1225   2019.9Essential and distinct roles of phosphatidylinositol 4-kinases, Pik1p and Stt4p, in yeast autophagy.

2. Tsuji, T., Cheng, J., Tatematsu, T., Ebata, A., Kamikawa, H., Fujita, A., Gyobu, S., Segawa, K., Arai, H., Taguchi, T., Nagata, S., Fujimoto, T. .  Predominant localization of phosphatidylserine at the cytoplasmic leaflet of the ER, and its TMEM16K-dependent redistribution. .  Proc. Natl. Acad. Sci. U S A.116   13368 - 13373   2019.7Predominant localization of phosphatidylserine at the cytoplasmic leaflet of the ER, and its TMEM16K-dependent redistribution.Reviewed

4. Kurokawa, Y., Yoshida, A., Fujii, E., Tomioku, K., Hayashi, H., Tanabe, K., Fujita, A. .  Phosphatidylinositol 4-phosphate on Rab7-positive autophagosomes revealed by the freeze-fracture replica labeling. .  Traffic20   82 - 95   2019.1Phosphatidylinositol 4-phosphate on Rab7-positive autophagosomes revealed by the freeze-fracture replica labeling.Reviewed

5. Tsuji, T., Fujita, A., Fujimoto, T. .  Immunoelectron Microscopy of Gangliosides. .  Methods Mol. Biol.1804   231 - 239   2018.11Reviewed

1. Tomioku, K.N., Shigekuni, M., Hayashi, H., Yoshida, A., Futagami, T., Tamaki, H., Tanabe, K., Fujita, A. .  Nanoscale domain formation of phosphatidylinositol 4-phosphate in the plasma and vacuolar membranes of living yeast cells. .  Eur. J. Cell Biol.97   269 - 278   2018.3Reviewed

Yoshida A, Hayashi H, Tanabe K, Fujita A .  Segregation of phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate into distinct microdomains on the endosome membrane .  Biochim Biophys Acta1859 ( 10 ) 1880 - 1890   2017.7Segregation of phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate into distinct microdomains on the endosome membraneReviewed

Yoshida, A., Shigekuni, M., Tanabe, K., Fujita, A. .  Nanoscale analysis reveals agonist-sensitive and heterogeneous pools of phosphatidylinositol 4-phosphate in the plasma membrane. .  Biochim. Biophys. Acta. 1858 ( 6 ) 1298 - 1305   2016.3Nanoscale analysis reveals agonist-sensitive and heterogeneous pools of phosphatidylinositol 4-phosphate in the plasma membrane.Reviewed

Henry, Y., Morikawa, Y., Oe, N., Ikeda, N., Fujita, A., Takei, K., Minogue, S., Tatabe, K. .  PtdIns4KIIα generates endosomal PtdIns(4)P and is required for receptor sorting at early endosomes. .  Mol. Biol. Cell27 ( 6 ) 990 - 1001   2016.1PtdIns4KIIα generates endosomal PtdIns(4)P and is required for receptor sorting at early endosomes.Reviewed

Fujita, A., Inanobe, A., Hibino, H., Nielsen, S., Ottersen, OP., Kurachi, Y. .  Clustering of Kir4.1 at the specialized compartments of the lateral membrane in ependymal cells of rat brain .  Cell Tissue Res359 ( 2 ) 627 - 634   2015.12Clustering of Kir4.1 at the specialized compartments of the lateral membrane in ependymal cells of rat brainReviewed

Cheng, J., Fujita, A., Yamamoto, H., Tatematsu, T., Kakuta, S., Obara, K., Ohsumi, Y., Fujimoto, T. .  Yeast and mammalian autophagosomes exhibit distinct phosphatidylinositol 3-phosphate asymmetries. .  Nat. Commun.5   3207   2014.2Yeast and mammalian autophagosomes exhibit distinct phosphatidylinositol 3-phosphate asymmetries.Reviewed

Fujita, A., Fujimoto, T., Ozato-Sakurai, N., Suzuki, H. .  A method for efficient observation of intracellular membranes of monolayer culture cells by quick-freeze and freeze-fracture electron microscopy. .  J. Electron. Microsc. (Tokyo)61 ( 6 ) 441 - 446   2012.11A method for efficient observation of intracellular membranes of monolayer culture cells by quick-freeze and freeze-fracture electron microscopy.Reviewed

Ozato-Sakurai, N., Fujita, A., Fujimoto, T. .  The distribution of phosphatidy linositol 4,5-bisphosphate in acinar cells of rat pancreas revealed with the freeze-fracture replica labeling method. .  PLoS One. 6   e23567   2011.8The distribution of phosphatidy linositol 4,5-bisphosphate in acinar cells of rat pancreas revealed with the freeze-fracture replica labeling method.Reviewed

Kawai, Y., Hamazaki, Y., Fujita, H., Fujita, A., Sato, T., Furuse, M., Fujimoto, T., Jetten, A.M., Agata, Y., Minato, N. .  Claudin-4 induction by E-protein activity in later stages of CD4/8 double-positive thymocytes to increase positive selection efficiency. .  Proc. Natl. Acad. Sci. U S A. 108   4075 - 4080   2011.3Claudin-4 induction by E-protein activity in later stages of CD4/8 double-positive thymocytes to increase positive selection efficiency.Reviewed

Fujita, A., Cheng, J., Fujimoto, T. .  Quantitative electron microscopy for the nanoscale analysis of membrane lipid distribution. .  Nat. Protoc. 5   661 - 669   2010.3Quantitative electron microscopy for the nanoscale analysis of membrane lipid distribution. Reviewed

Fujita, A., Fujimoto T. .  High resolution molecular localization by freeze-fracture replica labeling. .  Methods Mol. Biol.657   205 - 216   2010High resolution molecular localization by freeze-fracture replica labeling.Reviewed

Cheng, J., Fujita, A., Ohsaki, Y., Suzuki, M., Shinohara, Y., Fujimoto, T. .  Quantitative electron microscopy shows uniform incorporation of triglycerides into existing lipid droplets. .  Histochem. Cell Biol.132   281 - 291   2009.6Quantitative electron microscopy shows uniform incorporation of triglycerides into existing lipid droplets. Reviewed

Fujita, A., Cheng, J., Tauchi-Sato, K., Takenawa, T., Fujimoto, T. .  A distinct pool of phosphatidylinositol 4,5-bisphosphate in caveolae revealed by a nanoscale labeling technique. .  Proc. Natl. Acad. Sci. U S A. 106   9256 - 9261   2009.6A distinct pool of phosphatidylinositol 4,5-bisphosphate in caveolae revealed by a nanoscale labeling technique.Reviewed

Fujita, A., Cheng, J., Fujimoto, T. .  Segregation of GM1 and GM3 clusters in the cell membrane depends on the intact actin cytoskeleton. .  Biochim. Biophys. Acta. 1791   388 - 396   2009.1Segregation of GM1 and GM3 clusters in the cell membrane depends on the intact actin cytoskeleton.Reviewed

Ohsaki, Y., Cheng, J., Suzuki, M., Fujita, A., Fujimoto, T. .  Lipid droplets are arrested in the ER membrane by tight binding of lipidated apolipoprotein B-100. .  J. Cell Sci. 121   2415 - 2422   2008.7Lipid droplets are arrested in the ER membrane by tight binding of lipidated apolipoprotein B-100. Reviewed

Kurahashi, M., Niwa, Y., Cheng, J., Ohsaki, Y., Fujita, A., Goto, H., Fujimoto, T., Torihashi, S. .  Platelet-derived growth factor signals play critical roles in differentiation of longitudinal smooth muscle cells in mouse embryonic gut. .  Neurogastroenterol. Motil. 20   521 - 531   2008.5Platelet-derived growth factor signals play critical roles in differentiation of longitudinal smooth muscle cells in mouse embryonic gut.Reviewed

Nakajima, H., Goto, H., Azuma, Y.T., Fujita, A., Takeuchi, T. .  Functional interactions between the SK2 channel and the nicotinic acetylcholine receptor in enteric neurons of the guinea pig ileum. .  J. Neurochem. 103   2428 - 2438   2007.12Functional interactions between the SK2 channel and the nicotinic acetylcholine receptor in enteric neurons of the guinea pig ileum. Reviewed

Fujita, A., Fujimoto, T. .  Quantitative retention of membrane lipids in the freeze-fracture replica. .  Histochem. Cell Biol. 128   385 - 389   2007.9Quantitative retention of membrane lipids in the freeze-fracture replica. Reviewed

Nakajima, H., Amano, W., Fujita, A., Fukuhara, A., Azuma, Y.T., Hata, F., Inui, T., Takeuchi, T. .  The active site cysteine of the proapoptotic protein glyceraldehyde-3-phosphate dehydrogenase is essential in oxidative stress-induced aggregation and cell death. .  J. Biol. Chem. 282   26562 - 26574   2007.9The active site cysteine of the proapoptotic protein glyceraldehyde-3-phosphate dehydrogenase is essential in oxidative stress-induced aggregation and cell death. Reviewed

Fujita, A., Cheng, J., Hirakawa, M., Furukawa, K., Kusunoki, S., Fujimoto, T. .  Gangliosides GM1 and GM3 in the living cell membrane form clusters susceptible to cholesterol depletion and chilling. .  Mol. Biol. Cell. 18   2112 - 2122   2007.6Gangliosides GM1 and GM3 in the living cell membrane form clusters susceptible to cholesterol depletion and chilling. Reviewed

Tsuiki, E., Fujita, A., Ohsaki, Y., Cheng, J., Irie, T., Yoshikawa, K., Senoo, H., Mishima, K., Kitaoka, T., Fujimoto, T. .  All-trans-retinol generated by rhodopsin photobleaching induces rapid recruitment of TIP47 to lipid droplets in the retinal pigment epithelium. Invest. .  Ophthalmol. Vis. Sci. 48   2858 - 2867   2007.6All-trans-retinol generated by rhodopsin photobleaching induces rapid recruitment of TIP47 to lipid droplets in the retinal pigment epithelium. Invest. Reviewed

Cheng, J., Ohsaki, Y., Tauchi-Sato, K., Fujita, A., Fujimoto, T. .  Cholesterol depletion induces autophagy. .  Biochem. Biophys. Res. Comm.351   246 - 252   2006.10Cholesterol depletion induces autophagy. Reviewed

Ohsaki, Y., Cheng, J., Fujita, A., Tokumoto, T., Fujimoto, T. .  Cytoplasmic lipid droplets are sites of convergence of proteasomal and autophagic degradation of apolipoprotein .  B. Mol. Biol. Cell. 17   2674 - 2683   2006.6Cytoplasmic lipid droplets are sites of convergence of proteasomal and autophagic degradation of apolipoprotein Reviewed

Mukai, K., Takeuchi, T., Toyoshima, M., Satoh, Y., Fujita, A., Shintani, N., Hashimoto, H., Baba, A., Hata, F. .  PACAP- and PHI-mediated sustained relaxation in circular muscle of gastric fundus: findings obtained in PACAP knockout mice. .  Regul. Pept. 133   54 - 61   2006.1PACAP- and PHI-mediated sustained relaxation in circular muscle of gastric fundus: findings obtained in PACAP knockout mice. Reviewed

Takeuchi, T., Fujinami, K., Goto, H., Fujita, A., Taketo, M.M., Manabe, T., Matsui, M., Hata, F. .  Roles of M2 and M4 muscarinic receptors in regulating acetylcholine release from myenteric neurons of mouse ileum. .  J. Neurophysiol. 93   2841 - 2848   2005.5Roles of M2 and M4 muscarinic receptors in regulating acetylcholine release from myenteric neurons of mouse ileum. Reviewed

Okishio, Y., Takeuchi, T., Fujita, A., Suenaga, K., Fujinami, K., Munakata, S., Hata, F. .  Examination of the role of cholinergic myenteric neurons with the impairment of neural reflexes in the ileum of c-kit mutant mice. .  J. Smooth Muscle Res.41   49 - 60   2005.2Examination of the role of cholinergic myenteric neurons with the impairment of neural reflexes in the ileum of c-kit mutant mice.Reviewed

Kirkham, M., Fujita, A., Chadda, R., Nixon, S.J., Kurzchalia, T.V., Sharma, D.K., Pagano, R.E., Hancock, J.F., Mayor, S., Parton, R.G. .  Ultrastructural identification of uncoated caveolin-independent early endocytic vehicles. .  J. Cell Biol.168   465 - 476   2005.1Ultrastructural identification of uncoated caveolin-independent early endocytic vehicles. Reviewed

Okishio, Y., Takeuchi, T., Fujita, A., Suenaga, K., Fujinami, K., Munakata, S., Takewaki, T. , Hata, F. .  Ascending contraction and descending relaxation in the distal colon of mice lacking interstitial cells of Cajal. .  J. Smooth Muscle Res. 41   163 - 174   2005.1Ascending contraction and descending relaxation in the distal colon of mice lacking interstitial cells of Cajal. Reviewed

Waseda, K., Takeuchi, T., Ohta, M., Okishio, Y., Fujita, A., Hata, F., Takewaki, T. .  Participation of ATP in nonadrenergic, noncholinergic relaxation of longitudinal muscle of wistar rat jejunum. .  J. Pharmacol. Sci. 97   91 - 100   2005.1 Participation of ATP in nonadrenergic, noncholinergic relaxation of longitudinal muscle of wistar rat jejunum. Reviewed

Fujita, A., Okishio, Y., Fujinami, K., Nakagawa, M., Takeuchi, T., Takewaki, T., Hata, F. .  Role of the interstitial cells distributed in the myenteric plexus in neural reflexes in the mouse ileum. .  J. Pharmacol. Sci.96   483 - 492   2004.12Role of the interstitial cells distributed in the myenteric plexus in neural reflexes in the mouse ileum. Reviewed

Hibino, H., Fujita, A., Iwai, K., Yamada, M., Kurachi, Y. .  Differential assembly of inwardly rectifying K+ channel subunits, Kir4.1 and Kir5.1, in brain astrocytes. .  J. Biol. Chem. 279   44065 - 44073   2004.10Differential assembly of inwardly rectifying K+ channel subunits, Kir4.1 and Kir5.1, in brain astrocytes. Reviewed

Takeuchi, T., Kushida, M., Hirayama, N., Kitayama, M., Fujita, A., Hata, F. .  Mechanisms involved in carbachol-induced Ca2+ sensitization of contractile elements in rat proximal and distal colon. .  Br. J. Pharmacol. 142   657 - 666   2004.6Mechanisms involved in carbachol-induced Ca2+ sensitization of contractile elements in rat proximal and distal colon. Reviewed

Takeuchi. T., Fujinami, K., Fujita, A., Okishio, Y., Takewaki, T., Hata, F. .  Essential role of the interstitial cells of Cajal in nitric oxide-mediated relaxation of longitudinal muscle of the mouse ileum. .  J. Pharmacol. Sci. 95   71 - 80   2004.5Essential role of the interstitial cells of Cajal in nitric oxide-mediated relaxation of longitudinal muscle of the mouse ileum. Reviewed

Takeuchi, T., Yamazaki, Y., Negoro, T., Fujinami, K., Mukai, K., Fujita, A., Takewaki, T., Hata, F. .  Changes in mechanism of PACAP-induced relaxation in longitudinal muscle of the distal colon of Wistar rats with age. .  Regul. Pept. 118   1 - 9   2004.4Changes in mechanism of PACAP-induced relaxation in longitudinal muscle of the distal colon of Wistar rats with age. Reviewed

Takeuchi, T., Kushida, M., Kitayama, M., Fujita, A., Hata, F. .  Origin of ATP for Ca2+-induced contraction in the guinea-pig femoral artery. .  Naunyn. Schmiedebergs Arch. Pharmacol. 369   350 - 357   2004.3 Origin of ATP for Ca2+-induced contraction in the guinea-pig femoral artery. Reviewed

Hibino, H., Higashi-Shingai, K., Fujita, A., Iwai, K., Ishii, M., Kurachi, Y. .  Expression of an inwardly rectifying K+ channel, Kir5.1, in specific types of fibrocytes in the cochlear lateral wall suggests its functional importance in the establishment of endocochlear potential. .  Eur. J. Neurosci. 19   76 - 84   2004.1Expression of an inwardly rectifying K+ channel, Kir5.1, in specific types of fibrocytes in the cochlear lateral wall suggests its functional importance in the establishment of endocochlear potential.Reviewed

藤田 秋一，置塩 豊，竹内 正吉，畑 文明 .  マウス腸管運動調節におけるカハールの介在細胞の役割 .  日薬理誌123   170 - 178   2004マウス腸管運動調節におけるカハールの介在細胞の役割Reviewed

Kushida, M., Takeuchi, T., Fujita, A., Hata, F. .  Dependence of Ca2+-induced contraction on ATP in alpha-toxin-permeabilized preparations of rat femoral artery. .  J. Pharmacol. Sci. 93   171 - 179   2003.10Dependence of Ca2+-induced contraction on ATP in alpha-toxin-permeabilized preparations of rat femoral artery. Reviewed

Ishii, M., Fujita, A., Iwai, K., Kusaka, S., Higashi, K., Inanobe, A., Hibino, H., Kurachi, Y. .  Differential expression and distribution of Kir5.1 and Kir4.1 inwardly rectifying K+ channels in retina. .  Am. J. Physiol. Cell Physiol.285   C260 - C267   2003.8Differential expression and distribution of Kir5.1 and Kir4.1 inwardly rectifying K+ channels in retina.Reviewed

Takeuchi, T., Kitayama, M., Kushida, M., Fujita, A., Hata, F. .  Essential role of ATP synthesized by creatine kinase in contraction of alpha-toxin permeabilized preparations of tonic type smooth muscle. .  J. Pharmacol. Sci. 92   374 - 380   2003.8Essential role of ATP synthesized by creatine kinase in contraction of alpha-toxin permeabilized preparations of tonic type smooth muscle. Reviewed

Fujita, A., Takeuchi, T., Hanai, J., Hata, F. .  Expression of the small conductance Ca2+-activated K+ channel, SK3, in the olfactory ensheating glial cells of rat brain. .  Cell Tiss. Res.313   187 - 193   2003.8Expression of the small conductance Ca2+-activated K+ channel, SK3, in the olfactory ensheating glial cells of rat brain.Reviewed

Fujita, A., Takeuchi, T., Hanai, J., Hata, F. .  Localization of Ca2+-activated K+ channel, SK3, in fibroblast-like cells forming gap junctions with smooth muscle cells in the mouse small intestine. .  J. Pharmacol. Sci.92   35 - 42   2003.5Localization of Ca2+-activated K+ channel, SK3, in fibroblast-like cells forming gap junctions with smooth muscle cells in the mouse small intestine. Reviewed

Takeuchi, T., Fujita, A., Kushida, M., Hata, F. .  The site where newly synthesized ATP is necessary for tension development in alpha-toxin permeabilized preparations of rat proximal colon. .  J. Pharmacol. Sci.91   277 - 284   2003.4The site where newly synthesized ATP is necessary for tension development in alpha-toxin permeabilized preparations of rat proximal colon. Reviewed

Chachin, M., Yamada, M., Fujita, A., Matsuoka, T., Matsushita, K., Kurachi, Y. .  Nateglinide, a D-phenylalanine derivative lacking either a sulfonylurea or benzamido moiety, specifically inhibits pancreatic β-cell-type KATP channels. .  J. Pharmacol. Exp. Ther. 304, 1025-1032, Mar, 2003.304   1025 - 1032   2003.3Nateglinide, a D-phenylalanine derivative lacking either a sulfonylurea or benzamido moiety, specifically inhibits pancreatic β-cell-type KATP channels. Reviewed

Yamaji, M., Ohta, M., Yamazaki, Y., Fujinami, K., Fujita, A., Takeuchi, T., Hata, F., Takewaki, T. .  A possible role of neurotensin in NANC relaxation of longitudinal muscle of the jejunum and ileum of Wistar rats. .  Br. J. Pharmacol. 137   629 - 636   2002.11A possible role of neurotensin in NANC relaxation of longitudinal muscle of the jejunum and ileum of Wistar rats. Reviewed

Mukai, K., Satoh, Y., Fujita, A., Takeuchi, T., Shintani, N., Hashimoto, H., Baba, A., Hata, F. .  PAC1 receptor-mediated relaxation of longitudinal muscle of the mouse proximal colon. .  Jpn. J. Pharmacol. 90   97 - 100   2002.9PAC1 receptor-mediated relaxation of longitudinal muscle of the mouse proximal colon.Reviewed

Inanobe, A., Fujita, A., Ito, M., Tomoike, H., Inageda, K., Kurachi, Y. .  Inward rectifier K+ channel Kir2.3 is localized at the postsynaptic membrane of excitatory synapses. .  Am. J. Physiol. Cell Physiol. 282   C1396 - C1403   2002.6Inward rectifier K+ channel Kir2.3 is localized at the postsynaptic membrane of excitatory synapses. Reviewed

Fujita, A., Horio, Y., Higashi, K., Mouri, T., Hata, F., Takeguchi, N., Kurachi, Y. .  Specific localization of an inwardly rectifying K+ channel, Kir4.1, at the apical membrane of rat gastric parietal cells; its possible involvement in K+ recycling for the H+/K+-pump. .  J. Physiol. (Lond) 540   85 - 92   2002.4Specific localization of an inwardly rectifying K+ channel, Kir4.1, at the apical membrane of rat gastric parietal cells; its possible involvement in K+ recycling for the H+/K+-pump.Reviewed

Tanemoto, M., Fujita, A., Higashi, K., Kurachi, Y. .  PSD-95 mediates formation of a functional homomeric Kir5.1 channel in the brain. .  Neuron34   387 - 397   2002.4PSD-95 mediates formation of a functional homomeric Kir5.1 channel in the brain.Reviewed

Matsushita, K., Kinoshita, K., Matsuoka, T., Fujita, A., Fujikado, T., Tano, Y., Nakamura, H., Kurachi, Y. .  Intramolecular interaction of SUR2 subtypes for intracellular ADP-Induced differential control of KATP channels. .  Circ. Res.90   554 - 561   2002.3Intramolecular interaction of SUR2 subtypes for intracellular ADP-Induced differential control of KATP channels. Reviewed

Takeuchi, T., Sumiyoshi, M., Kitayama, M., Hirayama, N., Fujita, A., Hata, F. .  Origin of Ca2+ necessary for carbachol-induced contraction in longitudinal muscle of the proximal colon of rats. .  Jpn. J. Pharmacol.87   309 - 317   2001.12Origin of Ca2+ necessary for carbachol-induced contraction in longitudinal muscle of the proximal colon of rats. Reviewed

Fujita, A., Takeuchi, T., Saitoh, N., Hanai, J., Hata, F. .  Expression of Ca2+-activated K+ channels, SK3, in the interstitial cells of Cajal in the gastrointestinal tract. .  Am. J. Physiol. Cell Physiol. 281   C1727 - C1733   2001.11Expression of Ca2+-activated K+ channels, SK3, in the interstitial cells of Cajal in the gastrointestinal tract. Reviewed

Fujita, A., Hattori,Y., Takeuchi, T., Kamata, Y., Hata, F. .  NGF induces neurite outgrowth via a decrease in phosphorylation of myosin light chain in PC12 cells. .  Neuroreport12   3599 - 3602   2001.11NGF induces neurite outgrowth via a decrease in phosphorylation of myosin light chain in PC12 cells.Reviewed

Satoh, Y., Uchida, M., Fujita, A., Nishio, H., Takeuchi, T., Hata, F. .  Possible role of orexin A in NANC inhibitory response of longitudinal muscle of the mouse small intestine. .  Eur. J. Pharmacol. 428   337 - 342   2001.10Possible role of orexin A in NANC inhibitory response of longitudinal muscle of the mouse small intestine. Reviewed

Higashi, K., Fujita, A., Inanobe, A., Tanemoto, M., Doi, K., Kubo, T., Kurachi, Y. .  An inwardly rectifying K+ channel, Kir4.1, expressed in astrocytes surrounds synapses and blood vessels in brain. .  Am. J. Physiol. Cell Physiol.281   C922 - C931   2001.9An inwardly rectifying K+ channel, Kir4.1, expressed in astrocytes surrounds synapses and blood vessels in brain. Reviewed

Takeuchi, T., Fujita, A., Roumy, M., Zajac, J-M., Hata, F. .  Effect of 1Dme, a neuropeptide FF analog, on acetylcholine release from myenteric plexus of guinea pig ileum. .  Jpn. J. Pharmacol. ( 86 ) 417 - 422   2001.8Effect of 1Dme, a neuropeptide FF analog, on acetylcholine release from myenteric plexus of guinea pig ileum. Reviewed

Takeuchi, T., Sugimoto, K., Morimoto, H., Fujita, A., Hata, F. .  Mechanism of a nitric oxide donor, NOR1-induced relaxation in longitudinal muscle of rat proximal colon. .  Jpn. J. Pharmacol. 86   390 - 398   2001.8Mechanism of a nitric oxide donor, NOR1-induced relaxation in longitudinal muscle of rat proximal colon.Reviewed

Kusaka, S., Inanobe, A., Fujita, A., Makino, Y., Tanemoto, M., Matsushita, K., Tano, K., Kurachi, Y. .  Functional Kir7.1 channels localized at the root of apical processes in rat retinal pigment epithelium. .  J. Physiol. (Lond)531   27 - 36   2001.2Functional Kir7.1 channels localized at the root of apical processes in rat retinal pigment epithelium. Reviewed

Matsuoka, T., Matsushita, K., Katayama, Y., Fujita, A., Inageda, K., Tanemoto, M., Inanobe, A., Yamashita, S., Matsuzawa, Y., Kurachi, Y. .  C-terminal tails of sulfonylurea receptors control ADP-induced activation and diazoxide modulation of ATP-sensitive K+ channels. .  Circ. Res. 87   873 - 880   2000.11C-terminal tails of sulfonylurea receptors control ADP-induced activation and diazoxide modulation of ATP-sensitive K+ channels.Reviewed

Takeuchi, T., Negoro, T., Yamaji, M., Yamazaki, Y., Fujita, A., Nishio, H., Takewaki, T., Takatsuji, K., Hata, F. .  Increase in participation of vasoactive intestinal peptide in relaxation of the distal colon of wistar rats with age. .  Br. J. Pharmacol. 131   942 - 948   2000.11Increase in participation of vasoactive intestinal peptide in relaxation of the distal colon of wistar rats with age.Reviewed

Katayama, Y., Fujita, A., Ohe, T., Findlay, I., Kurachi, Y. .  Inhibitory effects of vesnarinone on cloned cardiac delayed rectifier K+ channels expressed in a mammalian cell line. .  J. Pharmacol. Exp. Ther. 294   339 - 346   2000.7Inhibitory effects of vesnarinone on cloned cardiac delayed rectifier K+ channels expressed in a mammalian cell line. Reviewed

Hibino, H., Inanobe, A., Tanemoto, M., Fujita, A., Doi, K., Kubo, T., Hata, Y., Takai, Y., Kurachi, Y. .  Anchoring proteins confer G protein sensitivity to an inward-rectifier K+ channel through the GK domain. .  EMBO J. 19   78 - 83   2000.1Anchoring proteins confer G protein sensitivity to an inward-rectifier K+ channel through the GK domain. Reviewed

Inanobe, A., Horio, Y., Fujita, A., Tanemoto, M., Hibino, H., Inageda, K., Kurachi, Y. .  Molecular cloning and characterization of a novel splicing variant of the Kir3.2 subunit predominantly expressed in mouse testis. .  J. Physiol. (Lond) 521   19 - 30   1999.11Molecular cloning and characterization of a novel splicing variant of the Kir3.2 subunit predominantly expressed in mouse testis. Reviewed

Fujita, A., Horio, Y., Nielsen, S., Nagelhus, E.A., Hata, F., Ottersen, O.P., Kurachi, Y. .  High-resolution immunogold cytochemistry indicates that AQP4 is concentrated along the basal membrane of parietal cell in rat stomach. .  FEBS Let. 459   305 - 309   1999.10High-resolution immunogold cytochemistry indicates that AQP4 is concentrated along the basal membrane of parietal cell in rat stomach. Reviewed

Kusaka, S., Horio, Y., Fujita, A., Matsushita, K., Inanobe, A., Gotow, T., Uchiyama, Y., Tano, Y., Kurachi, Y. .  Expression and polarized distribution of an inwardly rectifying K+ channel, Kir4.1, in rat retinal pigment epithelium. .  J. Physiol. (Lond) 520   373 - 381   1999.10Expression and polarized distribution of an inwardly rectifying K+ channel, Kir4.1, in rat retinal pigment epithelium. Reviewed

Hibino, H., Horio, Y., Fujita, A., Inanobe, A., Doi, K., Gotow, T., Uchiyama, Y., Kubo, T., Kurachi, Y. .  Expression of an inwardly rectifying K+ channel, Kir4.1, in the satelite cells of rat cochlear ganglia. .  Am. J. Physiol. Cell Physiol.277   C638 - C644   1999.10Expression of an inwardly rectifying K+ channel, Kir4.1, in the satelite cells of rat cochlear ganglia. Reviewed

Repunte, V.P., Nakamura, H., Fujita, A., Horio, Y., Findlay, I., Pott, L., Kurachi, Y. .  Extracellular links in Kir subunits control the unitary conductance of SUR/Kir6.0 ion channels. .  EMBO J.18   3317 - 3324   1999.6Extracellular links in Kir subunits control the unitary conductance of SUR/Kir6.0 ion channels. Reviewed

Nagelhus, E.A., Horio, Y., Inanobe, A., Fujita, A., Haug, F-M., Nielsen, S., Kurachi, Y., Ottersen, O.P. .  Immunogold evidence suggests that coupling of K+ siphoning and water transport in rat retinal Muller cells is mediated by a coenrichment of Kir4.1 and AQP4 in specific membrane domains. .  Glia26   47 - 54   1999.3Immunogold evidence suggests that coupling of K+ siphoning and water transport in rat retinal Muller cells is mediated by a coenrichment of Kir4.1 and AQP4 in specific membrane domains. Reviewed

Murahashi, T., Fujita, A., Kitazawa, T. .  Ca2+-induced Ca2+ desensitization of myosin light chain phosphrylation and contraction in phasic smooth muscle. .  Mol. Cell. Biochem. 190   91 - 98   1999.1Ca2+-induced Ca2+ desensitization of myosin light chain phosphrylation and contraction in phasic smooth muscle. Reviewed

Kim, D., Fujita, A., Horio, Y., Kurachi, Y. .  Cloning and functional expression of a novel cardiac two-pore background K+ channel (cTBAK-1). .  Circ. Res. 82   513 - 518   1998.3Cloning and functional expression of a novel cardiac two-pore background K+ channel (cTBAK-1). Reviewed

Fujita, A., Takeuchi, T., Ishii,T., Nishio, H., Hata, F. .  Cooperation of ATP and norepinephrine in inducing contraction in guinea pig vas deferens is not associated with change in intracellular Ca2+ level. .  Jpn. J. Pharmacol. 70   273 - 276   1996.3Cooperation of ATP and norepinephrine in inducing contraction in guinea pig vas deferens is not associated with change in intracellular Ca2+ level. Reviewed

Takeuchi, T., Fujita, A., Ishii, T., Nishio, H., Hata, F. .  Necessity of newly synthesized ATP by creatine kinase for contraction permeabilized longitudinal muscle preparations of rat proximal colon. .  J. Pharmacol. Exper. Ther.275   429 - 434   1995.10Necessity of newly synthesized ATP by creatine kinase for contraction permeabilized longitudinal muscle preparations of rat proximal colon. Reviewed

Fujita, A., Takeuchi, T., Nakajima, H., Nishio, H., Hata, F. .  Involvement of heterotrimeric GTP-binding protein and rho protein, but not protein kinase C, in agonist-induced Ca2+ sensitization of skinned muscle of guinea pig vas deferens. .  J. Pharmacol. Exper. Ther.274   555 - 561   1995.7Involvement of heterotrimeric GTP-binding protein and rho protein, but not protein kinase C, in agonist-induced Ca2+ sensitization of skinned muscle of guinea pig vas deferens. Reviewed

Nagao, T., Fujita, A., Takeuchi, T., Hata, F. .  Changes in neuronal contribution to contractile responses of vas deferens of young and adult guinea pigs. .  J. Auton. Nerv. Syst.50   87 - 92   1994.12Changes in neuronal contribution to contractile responses of vas deferens of young and adult guinea pigs.Reviewed

Maehara, T., Fujita, A., Suthamnatpong, N., Takeuchi, T., Hata, F. .  Differences in relaxant effects of cyclic GMP on skinned muscle preparations from the proximal and distal colon of rats. .  Eur. J. Pharmacol.261   163 - 170   1994.8Differences in relaxant effects of cyclic GMP on skinned muscle preparations from the proximal and distal colon of rats.Reviewed

Fujita, A., Takeuchi, T., Hata, F., Yagasaki, O. .  Role of PGE2 in neurotransmission from pre- to post-ganglionic hypogastric nerves of guinea pigs. .  Jpn. J. Pharmacol.58   61 - 66   1992.1Role of PGE2 in neurotransmission from pre- to post-ganglionic hypogastric nerves of guinea pigs.Reviewed

免疫電顕法

藤本 豊士，藤田 秋一（ Role： Joint author）

「組織細胞化学2006」，日本組織細胞化学会編，学際企画，京都  2006 

SDS処理凍結割断レプリカ標識法（藤本法）

藤田 秋一，藤本 豊士（ Role： Joint author）

「染色・バイオイメージング実験ハンドブック」，高田邦昭，斉藤尚亮，川上速人 編, 羊土社，東京  2006 

超薄切片を用いた免疫電顕法

藤田 秋一，藤本 豊士（ Role： Joint author）

「組織細胞化学2005」，日本組織細胞化学会編，学際企画，京都  2005 

カリウムイオン

倉智 嘉久，藤田 秋一（ Role： Joint author）

「NEW薬理学」田中千賀子，加藤隆一 編，南光堂，東京  2001 

チャネル遺伝子発現システムとその解析法

藤田 秋一，藤田 聡，倉智 嘉久（ Role： Joint author）

「新パッチクランプ実験技術法」，岡田泰伸 編，吉岡書店，京都  2001 

膜電流系の受容体機構

藤田 秋一，倉智 嘉久（ Role： Joint author）

「新不整脈」，井上博 編，南光堂，東京  2001 

Regulation of Ion Channels by Membrane Proteins

Fujita, A., Hibino, H. and Kurachi, Y.（ Role： Joint author）

THE CELL PHYSIOLOGY SOURCE BOOK, Third Edition, edited by Sperelakis, N. ,Academic Press, San Diego  2000 

膜の構造と透過性

倉智 嘉久，藤田 秋一（ Role： Joint author）

『分子・細胞の生物学II-細胞』石川春律，高井義美，月田承一郎 編，「現代医学の基礎」，岩波書店，東京  2000 

The Inward Rectifying K+ channels in heart

Tanemoto, M., Fujita, A. and Kurachi, Y. （ Role： Joint author）

PHYSIOLOGY AND PATHOLOGY OF THE HEART, Fourth Edition, edited by Terzic, A. And Kurachi, Y., Kluwer Academic Publishers, Boston  2000 

Inward rectifying and ATP-sensitive K+ channels in the ventricular myocardium. Potassium channels in cardiovascular biology, edited by Archer, S.L. and Rush, N.J.

Fujita, A. and Kurachi, Y.（ Role： Joint author）

Plenum Press, New York  1999 

神経細胞イオンチャネル・受容体と細胞内分布

倉智 嘉久、藤田 秋一（ Role： Joint author）

「神経精神疾患理解のための病態生理」中村重信 編，神経精神疾患state of arts，医学のあゆみ，医歯薬出版社，東京  1999 

電子顕微鏡を用いた細胞内取込み現象の可視化

藤田 秋一

顕微鏡   41   57 - 60   2006

膜4回貫通型Two-pore domain K+ チャネル

藤田 秋一

「イオンチャネルの最前線」、倉智嘉久 編，医学のあゆみ   201   1043 - 1048   2002

チャネル・トランスポートのstructure-functionと薬物設計

藤田 秋一，松岡 哲郎，松下 賢治，倉智 嘉久

日薬理誌   118   177 - 186   2001

チャネル遺伝子発現システムとその解析法

藤田 秋一，藤田 聡，倉智 嘉久

「新パッチクランプ実験技術法」，岡田泰伸 編，吉岡書店、京都   260 - 272   2001

SAP family proteins. Reviewed

Fujita, A. and Kurachi, Y.

Biochem. Biophy. Res. Comm.   269   1 - 6   2000

イオンチャネルの概念と最近の動向

倉智 嘉久，藤田 秋一

「チャネロパチー」，岡本幸市 編，CLINICAL NEUROSCIENCE   18   256 - 261   2000

K+チャネル作用薬

倉智 嘉久，藤田 秋一

「最先端創薬」，長尾拓ほか編，蛋白質核酸酵素   45   1023 - 1031   2000

Molecular Aspects of KATP channels in the Cardiovascular System and K+ channel openers. Basic and Therapeutic Relevance of K+ channel Regulation, edited by A.C. Sartorelli, W.C. Bowman, M.J. Curtis and S.G. Amara, Reviewed

Fujita, A. and Kurachi, Y.

Pharmacol. Therapeut   85   39 - 53   2000

ATP感受性カリウムチャネル

藤田 秋一，倉智嘉久

脳の科学   20   101 - 103   1998

イオンチャネルカップル受容体

藤田 秋一，倉智嘉久

内分泌・糖尿病科   7   301 - 307   1998

藤田秋一，程晶磊，藤本豊士   免疫電顕法を用いたホスホイノシタイドの微細局在  

日本平滑筋学会総会  日本平滑筋学会総会

山口 優希, 黒川 夕奈, 向達 汐美, 福田 佳代子, 正谷 達謄, 藤田 秋一   酵母細胞でのautophagosome膜およびautophagic body膜における膜脂質の微細分布解析  

日本生化学会大会プログラム・講演要旨集  2021.11  (公社)日本生化学会

黒川 夕奈, 小西 里可子, 富奥 甘奈, 藤田 秋一   急速凍結・凍結割断レプリカ標識(QF-FRL)法を用いた酵母細胞膜におけるPI(4,5)P2の局在解析による、PI(4、5)P2生成の制御機構の解明  

日本生化学会大会プログラム・講演要旨集  2021.11  (公社)日本生化学会

向達 汐美, 正谷 達謄, 小西 里可子, 黒川 夕奈, 山口 優希, 富奥 甘奈, 福田 佳代子, ハキミ・ハッサン , 麻田 正仁, 金子 修, 藤田 秋一   ヒトmalaria原虫Plasmodium falciparumの細胞膜ではラフト主成分の糖脂質GM3は内葉と外葉の両方に局在する  

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向達 汐美, 正谷 達謄, 小西 里可子, 黒川 夕奈, 山口 優希, 富奥 甘奈, 福田 佳代子, ハキミ・ハッサン , 麻田 正仁, 金子 修, 藤田 秋一   ヒトmalaria原虫Plasmodium falciparumでのラフト主成分の糖脂質GM3の局在  

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