Gao Qinghua, Minobe Etsuko, Kameyama Masaki*, Xu Jianjun* .  Purification of insoluble GST-fused and GST-cleaved Cav1.2 channel fragment by denaturation and renaturation. .  Protein Expression and Purification160   7 - 10   2019.3Reviewed

Li J, Yu Z, Xu J, Feng R, Gao Q, Boczek T, Liu J, Li Z, Wang Q, Lei M, Gong J, Hu H, Minobe E, Ji HL, Kameyama M, Guo F .  The Effect of Ca2+, Lobe-Specificity, and CaMKII on CaM Binding to Nav1.1 .  Int J Mol Sci19 ( 9 )   2018.8Reviewed

Lei M, Xu J*, Gao Q, Minobe E, Kameyama M, Hao L* .  PKA phosphorylation of Cav1.2 channel modulates the interaction of calmodulin with the C terminal tail of the channel. .  J Pharmacol Sci137 ( 2 ) 187 - 194   2018.6Reviewed

Wu M, Takemoto M, Luo H, Xu JJ, Lu MH, Kameyama M, Takumi T, Song WJ .  A novel role of the antitumor agent tricyclodecan-9-yl-xanthogenate as an open channel blocker of KCNQ1/KCNE1 .  European Journal of Pharmacology 824   99 - 107   2018.4Reviewed

Lyu L, Gao Q, Xu J, Minobe E, Zhu T, Kameyama M .  A new interaction between proximal and distal C-terminus of Cav1.2 channels. .  Journal of Pharmacological Sciences   2017.3Reviewed

Chang Seok Lee, Amy D. Hanna, Hui Wang, Adan Dagnino-Acosta, Aditya D. Joshi, Mark Knoblauch, Yan Xia, Dimitra K. Georgiou, Jianjun Xu, Cheng Long, Hisayuki Amano, Corey Reynolds, Keke Dong, John C. Martin, William R. Lagor, George G. Rodney, Ergun Sahin, Caroline Sewry & Susan L. Hamilton .  A chemical chaperone improves muscle function in mice with a RyR1 mutation. .  Nature Communication   2017.3Reviewed

Yu L, Xu J, Minobe E, Kameyama A, Yang L, Feng R, Hao L, Kameyama M. .  Role of protein phosphatases in the run down of guinea pig cardiac Cav1.2 Ca2+ channels. .  American Journal of Physiology Cell Physiology310 ( 10 ) C773 - C779   2016.5Reviewed

Xu J, Yu L, Minobe E, Lu L, Lei M, Kameyama M. .  PKA and phosphatases attached to the Ca(V)1.2 channel regulate channel activity in cell-free patches. .  American Journal of Physiology Cell Physiology310 ( 2 ) C136 - C141   2016.1Reviewed

Sun Y, Xu J, Minobe E, Shimoara S, Hao L, Kameyama M. .  Regulation of the Cav1.2 cardiac channel by redox via modulation of CaM interaction with the channel. .  Journal of Pharmacological Sciences128 ( 3 ) 137 - 143   2015.7Reviewed

Shu-yuan Liu, Jian-jun Xu, Etsuko Minobe, Qing-hua Gao, Rui Feng, Mei-mi Zhao, Feng Guo, Lei Yang, Li-ying Hao, Masaki Kameyama .  Nucleotides maintain the activity of Cav1.2 channels in guinea-pig ventricular myocytes. .  Biochemical and Biophysical Research Communications460 ( 3 ) 813 - 818   2015.5Reviewed

Minobe E, Maeda S, Xu J, Hao L, Kameyama A, Kameyama M. .  A new phosphorylation site in cardiac L-type Ca2+ channels (Cav1.2) responsible for its cAMP-mediated modulation. .  Am J Physiol Cell Physiol306 ( 9 ) C856 - C863   2014.12Reviewed

Shao D, Zhao M, Xu J, Feng R, Guo F, Hu H, Sun X, Gao Q, He G, Sun W, Wang H, Yu L, Liu S, Zhu Y, Minobe E, Zhu T, Kameyama M, Hao L. .  The individual N- and C-lobes of calmodulin tether to the Cav1.2 channel and rescue the channel activity from run-down in ventricular myocytes of guinea-pig heart. .  FEBS Lett588 ( 21 ) 3855 - 3861   2014.11Reviewed

Lee CS, Georgiou DK, Dagnino-Acosta A, Xu J, Ismailov II, Knoblauch M, Monroe TO, Ji R, Hanna AD, Joshi AD, Long C, Oakes J, Tran T, Corona BT, Lorca S, Ingalls CP, Narkar VA, Lanner JT, Bayle JH, Durham WJ, Hamilton SL. .  Ligands for FKBP12 increase Ca2+ influx and protein synthesis to improve skeletal muscle function .  J Biol Chem289 ( 37 ) 25556 - 25570   2014.9Reviewed

Feng R, Xu J, Minobe E, Kameyama A, Yang L, Yu L, Hao L, Kameyama M. .  Adenosine triphosphate regulates the activity of guinea pig Cav1.2 channel by direct binding to the channel in a dose-dependent manner. .  Am J Physiol Cell Physiol   2014.2Reviewed

Yang L, Xu J, Minobe E, Yu L, Feng R, Kameyama A, Yazawa K, Kameyama M. .  Mechanisms underlying the modulation of L-type Ca2+ channel by hydrogen peroxide in guinea pig ventricular myocytes. .  J Physiol Sci.   2013.7Reviewed

Han DY, Minobe E, Wang WY, Guo F, Xu JJ, Hao LY, Kameyama M. .  Calmodulin- and Ca2+-dependent facilitation and inactivation of the Cav1.2 Ca2+ channels in guinea-pig ventricular myocytes. .  J Pharmacol Sci.112 ( 3 ) 310 - 319   2010Reviewed

Hao LY, Wang WY, Minobe E, Han DY, Xu JJ, Kameyama A, Kameyama M. .  The distinct roles of calmodulin and calmodulin kinase II in the reversal of run-down of L-type Ca2+ channels in guinea-pig ventricular myocytes. .  J Pharmacol Sci.111 ( 4 ) 416 - 425   2009Reviewed

Hao LY, Xu JJ, Minobe E, Kameyama A, Kameyama M. .  Calmodulin kinase II activation is required for the maintenance of basal activity of L-type Ca2+ channels in guinea-pig ventricular myocytes. .  J Pharmacol Sci.108 ( 3 ) 290 - 300   2008Reviewed

Nie HG, Hao LY, Xu JJ, Minobe E, Kameyama A, Kameyama M. .  Distinct roles of CaM and Ca(2+)/CaM -dependent protein kinase II in Ca(2+) -dependent facilitation and inactivation of cardiac L -type Ca2+ channels. .  J Physiol Sci.57 ( 3 ) 167 - 173   2007Reviewed

Minobe E, Hao LY, Saud ZA, Xu JJ, Kameyama A, Maki M, Jewell KK, Parr T, Bardsley RG, Kameyama M. .  A region of calpastatin domain L that reprimes cardiac L-type Ca2+ channels. .  Biochem Biophys Res Commun.348 ( 1 ) 288 - 288   2006.1Reviewed

Zhou FW, Xu JJ, Zhao Y, LeDoux MS, Zhou FM. .  Opposite functions of histamine H1 and H2 receptors and H3 receptor in substantia nigra pars reticulata. .  J Neurophysiol.96 ( 3 ) 1581 - 1581   2006Reviewed

Jian-Jun Xu, Li-Ying Hao, Asako Kameyama, Masaki Kameyama .  Calmodulin reverses rundown of L-type Ca(2+) channels in guinea pig ventricular myocytes. .  American Journal of Physiology Cell Physiology287 ( 6 ) C1717 - C1724   2004.11Reviewed

Liu Shuyuan, Xu Jianjun, Minobe Etsuko, Kameyama Asako, Hao Liying and Kameyama Masaki   The role of nucleotides in regulation of cardiac Cav1.2 channel  

日本生理学大会  日本生理学大会

Shao Dongxue, Xu Jianjun, Zhao Meimi, Sun Yu, Minobe Etsuko, He Guilin, Feng Rui, Hu Huiyuan, Sun Xuefei, Guo Feng, Kameyama Masaki, and Hao Liying   The Lobe-specific interaction of calmodulin with cardiac Cav1.2 channel  

日本生理学大会  日本生理学大会

Rui Feng, Shuyuan Liu, Jian-jun Xu, Etsuko Minobe, Asako Kameyama,Li-ying Hao and Masaki Kameyama1   Properties of the ATP-binding site responsible for regulation of cardiac Ca2+ channels  

西日本生理学会  西日本生理学会

Xu Jianjun, Minobe Etsuko, Yang Lei, Yu Lifeng, Yazawa Kazuto, Kameyama A & Kameyama Masaki   PKA modulates Ca2+ channel activity induced by calmodulin in guinea-pig ventricular myocytes  

日本生理学大会  日本生理学大会

Yu LF, Xu JJ, Minobe E, Yang L, Kameyama A, Yazawa K, Hao LY & Kameyama M   Phospjorylation state determines calmodulin-induced activity of Cav1.2 Ca2+ channels  

西日本生理学会  西日本生理学会

Minobe E, Maeda S, Xu JJ, Hao LY, Feng R, Yazawa K, Kameyama A and Kameyama M.   Multiple funtional phosphorylation sites of protein kinase A in the C-terminal tail of Cav1.2 channel.  

日本生理学大会  日本生理学大会

Yang L, Xu JJ, Minobe E, Feng R, Kameyama A, Yazawa K and Kameyama M.   Mechanism underlying the modulation of L-type Ca2+ channel by hydrogen peroxide in guinea-pig ventricular myocytes.  

日本生理学大会  日本生理学大会

Kameyama M, Minobe E, Asmara H, Saud ZA, Han DY, Xu JJ, Kameyama A, Hao LY.   Multiple molecules of calmodulin are involved in the regulation of Cav1.2 channel.   International conference

Japan-Korea Joint Symposium  Japan-Korea Joint Symposium

Yang L, Xu JJ, Minobe E, Feng R, Kameyama A, Yazawa K and Kameyama M.   CaMKII-dependent and independent facilitation of L-type Ca2+ channels by hydrogen peroxide inguinea-pig ventricular myocytes.  

西日本生理学会  西日本生理学会

Yang L, Xu JJ, Minobe E, Feng R, Kameyama A. Yazawa, K and Kameyama M.   Facilitation of L-type Ca2+ channels by hydrogen peroxide in guinea-pig ventricular myocytes.   International conference

The 5th biennial meeting of society for free radical research-Asia  The 5th biennial meeting of society for free radical research-Asia

Xu JJ, Zahangir A, Liu Y, Yang L, Minobe E, Kameyama A, Yazawa K, Hao LY and Kameyama M.   Both PKA-mediated phosphorylation and calmodulin interaction are required for basal activity of cardiac L-type Ca2+ channel.  

日本生理学会大会  日本生理学会大会

蓑部悦子、森誠之、徐建軍、亀山正樹   カルモジュリンをリンクさせたCav1.2型Ca2+チャネルのCa2+依存性調節  

生理学研究所研究会  生理学研究所研究会

Xu JJ, Zahangir A, Liu Y, Yang L, Minobe E, Kameyama A, Yazawa K, Hao LY and Kameyama M.   PKA-mediated phosphorylation modulates the interaction of calmodulin with cardiac Cav1.2 Ca2+ channel.   International conference

The 9th Japan-Korea Joint Symposium on Brain Sciences, and Cardiac and Smooth Muscles  The 9th Japan-Korea Joint Symposium on Brain Sciences, and Cardiac and Smooth Muscles

Joshi AD, Ji RR, Xu JJ, Long C and Hamilton SL.   Role of Oxidative Stress, Autophagy and Apoptosis in the I4895T RyR1 Knockin Mice.   International conference

Annual Meeting of the American Biophysical Society  Annual Meeting of the American Biophysical Society

Long C, Xu JJ, Lanner J, Dong KK and Hamilton SL.   Regulation of E-C Coupling Via TβRI and FKBP12.   International conference

Annual Meeting of the American Biophysical Society  Annual Meeting of the American Biophysical Society

Lanner JT, Long C, Xu JJ, Baker MR and Hamilton SL   AICAR Prevents Heat-Induced Death in Mice with Malignant Hyperthermia.   International conference

Annual Meeting of the American Biophysical Society  Annual Meeting of the American Biophysical Society

Long C, Durham W, Xu JJ, Ji RR, Dong KK, Yang GJ, Wu GY and Hamilton SL   Biphasic Effects of FKBP12 on RyR1 Activity.   International conference

Annual Meeting of the American Biophysical Society  Annual Meeting of the American Biophysical Society

Xu JJ, Ji RR, Long C, Durham W, Cheng Q, Dong KK, Yang GJ and Hamilton SL   Muscle from mice heterozygous for a mutation that abolishes FKBP12 binding to RyR1 fatigue more slowly than wild type muscle.   International conference

Annual Meeting of the American Biophysical Society  Annual Meeting of the American Biophysical Society