Updated on 2024/10/11

写真a

 
OKAMURA Hiroaki
 
Organization
Research Field in Science, Science and Engineering Area Graduate School of Science and Engineering (Science) Department of Science Chemistry Program Professor
Title
Professor

Degree

  • Ph. D. ( 1995.1   Kyushu University )

Research Interests

  • 不斉合成

  • Organic synthesis

  • Organic chemistry

Research Areas

  • Nanotechnology/Materials / Synthetic organic chemistry

Education

  • Kyushu University

    1988.4 - 1992.3

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    Country: Japan

  • Kyushu University   Chemistry

    1983.4 - 1988.3

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    Country: Japan

Research History

  • Kagoshima University   Research Field in Science, Science and Engineering Area Graduate School of Science and Engineering (Science) Department of Science Chemistry Program   Professor

    2020.4

  • Kagoshima University

    1992.4

  • Kagoshima University   Research Field in Science, Science and Engineering Area Graduate School of Science and Engineering (Science) Chemistry and Bioscience Course   Professor

    1992.4 - 2020.3

Professional Memberships

  • 有機合成化学協会

    2015.10

  • 日本化学会

    2015.10

  • 香料・テルペンおよび精油化学に関する討論会

    2012.4

 

Papers

  • Matsuyama K., Inoue T., Muroga T., Arima N., Doe M., Tani F., Ookawa Y., Okamoto Y., Onitsuka S., Okamura H., Iwagawa T., Hamada T. .  New halogenated C<inf>15</inf> acetogenins from Okinawan sea hare Aplysia dactylomela .  Tetrahedron120   2022.8

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    Language:Japanese   Publisher:Tetrahedron  

    Two new C15 acetogenins 1 and 2, along with four known sesquiterpenes isolaurenisol (3), laurokamurene D (4), itomanol (5), and acetylelatol (6), were isolated from sea hare Aplysia dactylomela. The structures, including the relative stereochemistries, of 1 and 2 were determined based on spectroscopic evidence. Finally, the in vitro cytotoxicities of the six compounds against S1T cells, an adult T-cell leukemia cell line, were evaluated.

    DOI: 10.1016/j.tet.2022.132889

    Scopus

  • Hamada T. .  Two cytotoxic squalene-derived polyethers from the Japanese red alga Chondria armata .  Natural Product Research35 ( 23 ) 1 - 6   2020

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    Language:Japanese   Publisher:Natural Product Research  

    The red alga Chondria armata is known to produce and contain a rich diversity of secondary metabolites, such as domoic acid-related alkaloids and triterpene polyethers. Our investigation on red alga C. armata from Kagoshima coast, Japan, resulted in the isolation of two new triterpene polyethers, bandokorols A (1) and B (2). The structures of these compounds were determined based on spectroscopic data such as infrared (FTIR), 1H-NMR, APT, 1H–1H-COSY, HSQC, HMBC, NOESY and FAB mass spectrometry (HRFABMS). The anticancer potentials of these compounds were tested against adult T-cell leukaemia (ATL), S1T cells and their IC50 values are reported here.

    DOI: 10.1080/14786419.2020.1777411

    Scopus

    PubMed

  • Satoaki Onitsuka, Toshiyuki Hamada, Hiroaki Okamura .  Preparation of antimicrobial gold and silver nanoparticles from tea leaf extracts .  Colloids and Surfaces B: Biointerfaces173 ( 1 ) 242 - 248   2019.1Reviewed

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:Elsevier B.V.  

    DOI: 10.1016/j.colsurfb.2018.09.055

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    PubMed

  • Hamada T. .  Aaptamine-related alkaloid from the marine sponge aaptos aaptos .  Natural Product Communications14 ( 9 ) 1 - 3   2019

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    Publisher:Natural Product Communications  

    DOI: 10.1177/1934578X19863935

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  • Maeda K. .  Total Synthesis of the Claimed Structure of (±)-Hyptinin and Structural Revision of Natural Hyptinin .  Journal of Natural Products80 ( 5 ) 1446 - 1449   2017.5Invited Reviewed

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:Journal of Natural Products  

    DOI: 10.1021/acs.jnatprod.6b01116

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    PubMed

  • Darwish Mahmoud Ibrahiem Mohieeldin, Takenoshita Yuto, Hamada Toshiyuki, Onitsuka Satoaki, Kurawaki Junich, Okamura Hiroaki .  Spontaneous Preparation of Highly Stable Gold Nanoparticle Stabilized with <i>ω</i>-Sulfonylated Alkylsulfanylaniline .  日本油化学会誌66 ( 12 ) 1349 - 1354   2017

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    Publisher:公益社団法人 日本油化学会  

    <p>Preparation, characterization, and stability evaluation of gold nanoparticles stabilized by <i>ω-</i>sulfonylated alkylsulfanylaniline have been described. The particle solution was obtained by the spontaneous reaction of HAuCl<sub>4</sub> and <i>ω</i>-sulfonylated alkylsulfanylaniline in boiling water. It showed a deep red color, owing to surface plasmon resonance of the resulting gold nanoparticles. The size and shape of the nanoparticles were pH-dependent, and pH 8 was found to be the most suitable condition to prepare stable nanoparticles with an average size of 11.2 ± 5.9 nm. The resulting particle solution was stable for a wide range of pH (3–13) and in phosphate-buffered saline (PBS) solution. The nanoparticles were storable as dried powder for at least two weeks, and were redispersible in water or PBS to give almost the same absorption spectra as the freshly prepared solution. Nanoparticle modification was achieved by simply adding thiol molecules to the particle solution.</p>

    DOI: 10.5650/jos.ess17151

    Scopus

    PubMed

  • Ryuji Ohira, Toshiyuki Hamada, Satoaki Onitsuka, and Hiroaki Okamura .  Base-catalyzed Asymmetric Diels-Alder Reaction of N-Nosyl-3-hydroxy-2-pyridone with a Chiral Acrylate, and Its Application to the Synthesis of Aminocarbasugars .  GSTF Journal of Chemical Sciences2 ( 1 ) 16 - 20   2015.10Reviewed

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:Global Science and Technology Forum  

    A base-catalyzed asymmetric Diels-Alder reaction of N-sulfonylated 3-hydroxy-2-pyridone and a chiral acrylate has been developed. In the presence of a catalytic amount of cinchona alkaloid, the reaction proceeded smoothly in aqueous tetrahydrofuran and gave a highly functionalized bicyclolactam in good yield with up to 91% diastereoselectivity (de). Absolute configuration of the
    adduct was established as 1R, 4S, 8R, based on transformation to compounds with known configuration. Its
    synthetic utility was demonstrated by preparing 2- epivalidamine, 2,3-epivalidamine, and an enantiomer of a
    Tamiflu intermediate, in short steps.

    DOI: 10.5176/2339-5060_2.1.16

  • Yuji Koyanagi, Toshiyuki Hamada, Tetsuo Iwagawa, and Hiroaki Okamura .  Asymmetric Synthesis of Ampelomin A and ent-Epiampelomin A .  J. Oleo Science・日本油化学会64 ( 4 ) 449 - 454   2015.4Asymmetric Synthesis of Ampelomin A and ent-Epiampelomin AReviewed

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  • Takuya Ishida, Yukina Takahashi, Hiroaki Okamura, Junichi Kurawaki, Sunao Yamada .  Vibrational spectroscopic characterization of 4-acylamidobenzenethiol-stabilized gold nanoparticles .  Vibrational Spectroscopy73   10 - 14   2014.1Vibrational spectroscopic characterization of 4-acylamidobenzenethiol-stabilized gold nanoparticlesReviewed

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  • H. Okamura, F. Urabe, T. Hamada, and T. Iwagawa .  Base-catalyzed Asymmetric Diels-Alder Reaction of 3-Hydroxy-2-Pyrone and Simple Aryl Vinyl Sulfoxide: Asymmetric Synthesis of Carbaketopyranoses .  Bulletin of the Chemical Society of Japan85 ( 5 ) 631 - 633   2012.5Base-catalyzed Asymmetric Diels-Alder Reaction of 3-Hydroxy-2-Pyrone and Simple Aryl Vinyl Sulfoxide: Asymmetric Synthesis of CarbaketopyranosesReviewed

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  • 岡村浩昭、岩川哲夫、濱田季之 .  ジエンの活性化を基盤とする触媒的Diels-Alder反応の開発と生理活性シクロヘキセンオキシド類およびカルバ糖類合成への応用 .  有機合成化学協会誌, vol. 70, 227-23970 ( 3 ) 227 - 239   2012.3ジエンの活性化を基盤とする触媒的Diels-Alder反応の開発と生理活性シクロヘキセンオキシド類およびカルバ糖類合成への応用Reviewed

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

  • Kwati Leonard, Bashir Ahmmad, Hiroaki Okamura, Junichi Kurawaki .  In situ green synthesis of biocompatible ginseng capped gold nanoparticles with remarkable stability .  COLLOIDS AND SURFACES B-BIOINTERFACES82 ( 2 ) 391 - 396   2011.2In situ green synthesis of biocompatible ginseng capped gold nanoparticles with remarkable stabilityReviewed

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  • Hiroaki Okamura, Junich Kurawaki, Tetsuo Iwagawa, Toshiyuki Hamada, Masatake Kawashima .  One-step Preparation of Gold Nanoparticles Using 4-Acylamindothiophenol as a Reductive Stabilizer .  Chemistry Letters39   1258 - 1260   2010.12One-step Preparation of Gold Nanoparticles Using 4-Acylamindothiophenol as a Reductive StabilizerReviewed

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  • Kwati Leonarda, Masatake Kawashima, Hiroaki Okamura, Junichi Kurawaki .  One-pot sonochemical synthesis of dendron-stabilized gold nanoparticles as promising nano-hybrid with potential impact in biological application .  Materials Letters64   2240 - 2244   2010.10One-pot sonochemical synthesis of dendron-stabilized gold nanoparticles as promising nano-hybrid with potential impact in biological applicationReviewed

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  • Miyabi Hirashima, Kazuo Tsuda, Toshiyuki Hamada, Hiroaki Okamura, Tatsuhiko Furukawa, Shin-ichi Akiyama, Yusuke Tajitsu, Ryuji Ikeda, Masaharu Komatsu, Matsumi Doe, Yoshiki Morimoto, Motoo Shiro, Rob W. M. van Soest, Kaoru Takemura, Tetsuo Iwagawa .  Cytotoxic Isomalabaricane Derivatives and a Monocyclic Triterpene Glycoside from the Sponge Rhabdastrella globostellata .  JOURNAL OF NATURAL PRODUCTS73 ( 9 ) 1512 - 1518   2010.9Cytotoxic Isomalabaricane Derivatives and a Monocyclic Triterpene Glycoside from the Sponge Rhabdastrella globostellataReviewed

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  • H. Okamura, H. Iiji, T. Hamada, T. Iwagawa and H. Furuno .  Diels-Alder Reaction of alpha-Tropolone and Electron-Deficient Dienophiles prompted by Et3N or Silica Gel: A new Synthetic Method of Highly Functionalized Homobarrelenone Derivatives .  Tetrahedron65   10709 - 10714   2009.12Diels-Alder Reaction of alpha-Tropolone and Electron-Deficient Dienophiles prompted by Et3N or Silica Gel: A new Synthetic Method of Highly Functionalized Homobarrelenone DerivativesReviewed

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  • Tetsuo Iwagawa, Miho Miyazaki, Yukiko Yokogawa, Hiroaki Okamura, Munehiro Nakatani, Matsumi Doe, Yoshiki Morimoto, and Kaoru Takemura .  Aplysinopsin Dimers from a Stony Coral. Tubastraea aurea .  Heterocycles75 ( 8 ) 2023 - 2028   2008.8Aplysinopsin Dimers from a Stony Coral. Tubastraea aureaReviewed

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  • Kipassa, N. T. , Okamura, H., Kina,K., Hamada,T., Iwagawa, T. .  Efficient Short Step Synthesis of Corey’s Tamiflu Intermediate .  Org. Lett.10   815 - 816   2008.2Efficient Short Step Synthesis of Corey’s Tamiflu IntermediateReviewed

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  • Kipassa, N. T., Iwagawa, T., Okamura, H., Doe, M., Morimoto, Y., and Nakatani, M. .  Limonoids from the stem bark of Cedrela odorata .  Phytochemistry69   1782 - 1785   2008.1Limonoids from the stem bark of Cedrela odorataReviewed

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  • Kipassa, N. T., Okamura, H., Doe, M., Morimoto, Y., Iwagawa, T., Nakatani, M. .  Three new Mexicanolides from the root bark of Entandrophragma Angolense .  Heterocycles75 ( 1 ) 157 - 164   2008.1Three new Mexicanolides from the root bark of Entandrophragma AngolenseReviewed

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  • Okamura, H., Nagaike, H., Kipassa, NT., Iwagawa, T., Nakatani, M .  Total synthesof (+/-)-2-epi-validamine .  Heterocycles68 ( 12 ) 2587 - 2594   2006.12Total synthesof (+/-)-2-epi-validamineReviewed

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  • Iwagawa, T., Hashimoto, K., Okamura, H., Kurawaki, J., Nakatani, M., Hou, DX., Fujii, M., Doe, M., Morimoto, Y., Takemura, K .  Biscembranes from the soft coral Sarcophyton glaucum .  J. Nat. Prod.69 ( 8 ) 1130 - 1133   2006.8Biscembranes from the soft coral Sarcophyton glaucumReviewed

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  • Iwagawa, T., Babazono, K., Okamura, H., Nakatani, M., Doe, M., Morimoto, Y., Shiro, M., Takemura, K .  Briviolides, new briarane diterpenes from a gorgonian Briareum sp. .  Heterocycles65 ( 9 ) 2083 - 2093   2005.9Briviolides, new briarane diterpenes from a gorgonian Briareum sp.Reviewed

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  • Cho, GY., Okamura, H., Bolm, C. .  Synthesis and palladium-catalyzed coupling reactions of enantiopure p-bromophenyl methyl sulfoximine .  J. Org. Chem70 ( 6 ) 2346 - 2349   2005.3Synthesis and palladium-catalyzed coupling reactions of enantiopure p-bromophenyl methyl sulfoximineReviewed

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  • Iwagawa, T., Eguchi, S., Okamura, H., Nakatani, M. & Hase, T. .  New Phenylpropanoid Diglycosides from Viburnum furucatum .  South Pacific Studies25 ( 1 ) 1 - 5   2004.12New Phenylpropanoid Diglycosides from Viburnum furucatumReviewed

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  • Okamura, H., Bolm, C .  Sulfoximines: Synthesand catalytic applications .  Chem. Lett.33 ( 5 ) 482 - 487   2004.5Sulfoximines: Synthesand catalytic applicationsReviewed

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  • Okamura, H., Bolm, C. .  Rhodium-catalyzed imination of sulfoxides and sulfides: Efficient preparation of N-unsubstituted sulfoximines and sulfilimines .  Org. Lett.6 ( 8 ) 1305 - 1307   2004.4Rhodium-catalyzed imination of sulfoxides and sulfides: Efficient preparation of N-unsubstituted sulfoximines and sulfiliminesReviewed

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  • Saad, MMG., Iwagawa, Tetsuoetsuo, Okamura Hiroaki, Doe, Matsumi, Nakatani, Munehiro .  Three new mexicanolides from the stem bark of Swietenia mahogani JACQ. .  Heterocycles 63   389 - 399   2004.2Three new mexicanolides from the stem bark of Swietenia mahogani JACQ.Reviewed

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  • Bolm, Carsten, Okamura Hiroaki, Verrucci, Marinera .  Palladium-catalyzed intramolecular alpha-arylation of sulfoximines .  J. Organomet. Chem.687   444 - 450   2003.12Palladium-catalyzed intramolecular alpha-arylation of sulfoximinesReviewed

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  • Okamura Hiroaki, Shimizu, Hideki, Yamashita, Naomi, Iwagawa, Tetsuoetsuo, Nakatani, Munehiro .  Total synthesof (+)-epiepoformin and (-)-phyllostine .  Tetrahedron 59   10159 - 10164   2003.12Total synthesof (+)-epiepoformin and (-)-phyllostineReviewed

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  • Iwagawa, Tetsuoetsuo, Nishitani, N., Kurosaki, S., Okamura Hiroaki, Nakatani, Munehirounehiro, Doe, Matsumi, Takemura, K .  Briarlides, briarane diterpenes from a Gorgonian Briareum sp. .  J. Nat. Prod.66   1412 - 1415   2003.11Briarlides, briarane diterpenes from a Gorgonian Briareum sp.Reviewed

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  • Bolm, Carsten, Verrucci, Marinera, Simic, Oliver, Cozzi, PG., Raabe, G., Okamura Hiroaki .  A new class of C-1-symmetric monosulfoximine ligands for enantioselective hetero Diels-Alder reactions .  Chem. Commun.22   2826 - 2827   2003.6A new class of C-1-symmetric monosulfoximine ligands for enantioselective hetero Diels-Alder reactionsReviewed

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  • Iwagawa, Tetsuoetsuo, Miyazaki, M., Okamura Hiroaki, Nakatani, Munehirounehiro, Doe, Matsumi, Takemura, K .  Three novel bis(indole) alkaloids from a stony coral, Tubastraea sp. .  Tetrahedron Lett.44   2533 - 2535   2003.3Three novel bis(indole) alkaloids from a stony coral, Tubastraea sp.Reviewed

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  • Nakatani, Munehirounehiro, Maeda, S., Higashi, K., Kurawaki, J., Okamura Hiroaki, Iwagawa, Tetsuo .  Three new eremophilenolides from Ligularia hiberniflorum (Makino) Kitam. .  Heterocycles 60   373 - 378   2003.2Three new eremophilenolides from Ligularia hiberniflorum (Makino) Kitam.Reviewed

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  • Nakatani, Munehirounehiro, Abdelgaleil, SAM., Kassem, SMI., Takezaki, K., Okamura Hiroaki, Iwagawa, Tetsuoetsuo, Doe, Masumi .  Three new modified limonoids from Khaya senegalensis .  J. Nat. Prod.65   1219 - 1221   2002.8Three new modified limonoids from Khaya senegalensis Reviewed

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  • Shimizu, Hideki, Okamura Hiroaki, Yamashita, Naomi, Iwagawa, Tetsuoetsuo, Nakatani, Munehiro .  Synthesof (+)-epiepoformin using the base-catalyzed Diels-Alder., reaction of 3-hydroxy-2-pyrone .  Tetrahedron Lett.42   8649 - 8651   2001.12Synthesof (+)-epiepoformin using the base-catalyzed Diels-Alder., reaction of 3-hydroxy-2-pyroneReviewed

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  • Nakatani, Munehirounehiro, Abdelgaleil, SAM., Kurawaki, Junichi, Okamura Hiroaki, Iwagawa, Tetsuoetsuo, Doe, Masumi .  Antifeedant rings B and D opened limonoids from Khaya senegalensis .  J. Nat. Prod.64   1261 - 1265   2001.10Antifeedant rings B and D opened limonoids from Khaya senegalensis Reviewed

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  • Shimizu, Hideki, Okamura Hiroaki, Iwagawa, Tetsuoetsuo, Nakatani, Munehiro .  Asymmetric synthesof (-)- and (+)-eutipoxide B using a., base-catalyzed Diels-Alder reaction .  Tetrahedron 57   1903 - 1908   2001.3Asymmetric synthesof (-)- and (+)-eutipoxide B using a., base-catalyzed Diels-Alder reactionReviewed

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  • Abdelgaleil, SAM., Okamura Hiroaki, Iwagawa, Tetsuoetsuo, Sato, A., Miyahara, I., Doe, Matsumi, Nakatani, Munehiro .  Khayanolides, rearranged phragmalin limonoid antifeedants from Khaya., senegalensis .  Tetrahedron 39   119 - 126   2001.1Khayanolides, rearranged phragmalin limonoid antifeedants from Khaya., senegalensisReviewed

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  • Abdelgaleil, SAM., Okamura Hiroaki, Iwagawa, Tetsuoetsuo, Doe, Matsumi, Nakatani, Munehiro .  Novel rings B,D-secolimonoids from the stem bark of Khaya senegalensis .  Heterocycles 53   2233   2000.10Novel rings B,D-secolimonoids from the stem bark of Khaya senegalensisReviewed

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  • Okamura Hiroaki, Nagaike, H., Iwagawa, Tetsuoetsuo, Nakatani, Munehiro .  A base-catalyzed Diels-Alder reaction of N-tosyl-3-hydroxy-2-pyridone .  Tetrahedron Lett.41   8317 - 8321   2000.10A base-catalyzed Diels-Alder reaction of N-tosyl-3-hydroxy-2-pyridoneReviewed

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  • Iwagawa, Tetsuoetsuo, Kaneko, M., Okamura Hiroaki, Nakatani, Munehirounehiro, van Soest, RWM., Shiro, M .  A new quinolizidine alkaloid from the Papua New Guinean sponge., Xestospongia exigua .  J. Nat. Prod.63   1310 - 1311   2000.9A new quinolizidine alkaloid from the Papua New Guinean sponge., Xestospongia exiguaReviewed

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  • Iwagawa, Tetsuoetsuo, Hirose, T., Takayama, K., Okamura Hiroaki, Nakatani, Munehirounehiro, Doe, Matsumi, Takemura, K .  Violides N-P, new briarane diterpenes from a Gorgonacean Briareum sp. .  Heterocycles 53   1789   2000.8Violides N-P, new briarane diterpenes from a Gorgonacean Briareum sp.Reviewed

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  • Nakatani, Munehirounehiro, Abdelgaleil, SAM., Okamura Hiroaki, Iwagawa, Tetsuoetsuo, Sato, A., Doe, M .  Khayanolides A and B, new rearranged phragmalin limonoid antifeedants., from Khaya senegalensis .  Tetrahedron Lett.39   6473 - 6477   2000.8Khayanolides A and B, new rearranged phragmalin limonoid antifeedants., from Khaya senegalensisReviewed

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  • Okamura Hiroaki, Shimizu, H., Nakamura, Y., Iwagawa, Tetsuoetsuo, Nakatani, Munehiro .  Asymmetric synthesof the key intermediate of an SP antagonist., RPR107880 using a base-catalyzed Diels-Alder reaction .  Tetrahedron Lett.41   4147 - 4150   2000.5Asymmetric synthesof the key intermediate of an SP antagonist., RPR107880 using a base-catalyzed Diels-Alder reactionReviewed

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  • Iwagawa, Tetsuoetsuo, Nakamura, K., Hirose, T., Okamura Hiroaki, Nakatani, Munehiro .  New xenicane diterpenes isolated from the acetone extract of the soft., coral Xenia florida .  J. Nat. Prod.63   468 - 472   2000.4New xenicane diterpenes isolated from the acetone extract of the soft., coral Xenia floridaReviewed

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  • Nakatani, Munehirounehiro, Fukuman, Y., Sakumoto, T., Yamashita, N., Okamura Hiroaki, Iwagawa, Tetsuo .  Nimbolinins, C-seco limonoids from the fruits of Melia toosendan .  Heterocycles 53   689   2000.3Nimbolinins, C-seco limonoids from the fruits of Melia toosendanReviewed

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  • Iwagawa, Tetsuoetsuo, Takayama, K., Okamura Hiroaki, Nakatani, Munehirounehiro, Doe, Matsumi, Takemura, K., Shiro, M .  New briarane diterpenes from Briareum sp., collected at Bonotsu,., Kagoshima prefecture. 3. Cytotoxic briarane diterpenes from a., gorgonacean Briareum sp. .  Heterocycles 51   2619 - 2625   1999.11New briarane diterpenes from Briareum sp., collected at Bonotsu,., Kagoshima prefecture. 3. Cytotoxic briarane diterpenes from a., gorgonacean Briareum sp.Reviewed

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  • Nakatani, Munehirounehiro, Simokoro, M., Zhou, JB., Okamura Hiroaki, Iwagawa, Tetsuoetsuo, Tadera, K., Nakayama, N., Naoki, H .  Limonoids from Melia toosendan .  Phytochemistry 52   709 - 714   1999.10Limonoids from Melia toosendan Reviewed

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  • Iwagawa, Tetsuoetsuo, Takayama, K., Okamura Hiroaki, Nakatani, Munehirounehiro, Doe, H .  New briarane diterpenes from a gorgonacean Briareum sp. .  Heterocycles 51   1653   1999.7New briarane diterpenes from a gorgonacean Briareum sp.Reviewed

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  • Iwagawa, Tetsuoetsuo, Nakashima, R., Takayama, K., Okamura Hiroaki, Nakatani, Munehirounehiro, Doe, Matsumi, Shibata, K .  New cembranes from the soft coral Sarcophyton species .  J. Nat. Prod.62   1046 - 1049   1999.7New cembranes from the soft coral Sarcophyton species Reviewed

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  • Okamura Hiroaki, Iwagawa, Tetsuoetsuo, Nakatani, Munehiro .  Development of base catalyzed Diels-Alder reaction of., 3-hydroxy-2-pyrone and application to synthesof biologically active., compounds .  J. Synth. Org. Chem. Jpn.57   84 - 91   1999.2Development of base catalyzed Diels-Alder reaction of., 3-hydroxy-2-pyrone and application to synthesof biologically active., compoundsReviewed

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  • Nakatani, Munehirounehiro, Huang, RC., Okamura Hiroaki, Iwagawa, Tetsuoetsuo, Tadera, K .  Degraded limonoids from Melia azedarach .  Phytochemistry 49   1773 - 1776   1998.11Degraded limonoids from Melia azedarach Reviewed

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  • Iwagawa, Tetsuoetsuo, Kaneko, M., Okamura Hiroaki, Nakatani, Munehirounehiro, van Soest, RWM .  New alkaloids from the Papua New Guinean sponge Agelas nakamurai .  J. Nat. Prod.61   1310 - 1312   1998.10New alkaloids from the Papua New Guinean sponge Agelas nakamurai Reviewed

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  • Okamura Hiroaki, Morishige, K., Iwagawa, Tetsuoetsuo, Nakatani, Munehiro .  Asymmetric base-catalyzed Diels-Alder reaction of 3-hydroxy-2-pyrone., with chiral acrylate derivatives .  Tetrahedron Lett.39   1211 - 1214   1998.3Asymmetric base-catalyzed Diels-Alder reaction of 3-hydroxy-2-pyrone., with chiral acrylate derivativesReviewed

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  • Iwagawa, Tetsuoetsuo, Takenoshita, N., Okamura Hiroaki, Nakatani, Munehirounehiro, Doye, M., Shibata, K., Shiro, M .  New briarane diterpenes from a gorgonacean Briareum sp. .  Heterocycles 48   123 - 128   1998.1New briarane diterpenes from a gorgonacean Briareum sp.Reviewed

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  • Okamura Hiroaki, Yamauchi, Keiko, Miyawaki, Keiji, Iwagawa, Tetsuoetsuo, Nakatani, Munehiro .  Synthesand biological activities of degraded limonoids,., (+/-)-fraxinellonone and its related compounds .  Tetrahedron Lett.38   263 - 266   1997.1Synthesand biological activities of degraded limonoids,., (+/-)-fraxinellonone and its related compoundsReviewed

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  • Iwagawa, Tetsuoetsuo, Nakamura, S., Okamura Hiroaki, Nakatani, Munehiro .  Ichthyotoxic cembranoids from the soft coral, Sarcophyton sp .  Bull. Chem. Soc. Jpn.69   3543 - 3549   1996.12Ichthyotoxic cembranoids from the soft coral, Sarcophyton spReviewed

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  • Iwagawa, Tetsuoetsuo, Masuda, T., Okamura Hiroaki, Nakatani, Munehiro .  New xenia diterpenoids from a Xenia species of a soft coral .  Tetrahedron 52   13121 - 13128   1996.10New xenia diterpenoids from a Xenia species of a soft coral Reviewed

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  • Huang, RC., Tadera, K., Yagi, F., Minami, Y., Okamura Hiroaki, Iwagawa, Tetsuoetsuo, Nakatani, Munehiro .  Limonoids from Melia azedarach .  Phytochemistry 43   581 - 583   1996.10Limonoids from Melia azedarach Reviewed

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  • Iwagawa, Tetsuoetsuo, Amano, Y., Okamura Hiroaki, Nakatani, Munehirounehiro, Hase, Tsunao .  New xenia diterpenoids from Xenia sp Collected at Bonotsu, Kagoshima., prefecture .4. New xenia diterpenoids from a soft coral Xenia species .  Heterocycles 43   1271 - 1277   1996.6New xenia diterpenoids from Xenia sp Collected at Bonotsu, Kagoshima., prefecture .4. New xenia diterpenoids from a soft coral Xenia speciesReviewed

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  • Okamura Hiroaki, Nakamura, Yasuko, Iwagawa, Tetsuoetsuo, Nakatani, Munehiro .  Asymmetric base-catalyzed Diels-Alder reaction of 3-hydroxy-2-pyrone., with N-methylmaleimide .  Chem. Lett.   193 - 194   1996.3Asymmetric base-catalyzed Diels-Alder reaction of 3-hydroxy-2-pyrone., with N-methylmaleimideReviewed

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  • Nakatani, Munehirounehiro, Zhou, JB., Nakayama, N., Okamura Hiroaki, Iwagawa, Tetsuo .  Nimbolidins C-E, limonoid antifeedants from Melia toosendan .  Phytochemistry 41   739 - 743   1996.2Nimbolidins C-E, limonoid antifeedants from Melia toosendanReviewed

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  • Zhou, JB., Okamura Hiroaki, Iwagawa, Tetsuoetsuo, Nakatani, Munehiro .  Limonoid antifeedants from Melia toosendan .  Phytochemistry 41   117 - 120   1996.1Limonoid antifeedants from Melia toosendan Reviewed

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  • Zhou, JB., Okamura Hiroaki, Iwagawa, Tetsuoetsuo, Nakamura, Y., Nakayama, N., Tadera, K., Nakatani, Munehiro .  Trichilinins B and C, two new limonoids from Melia toosendan .  Heterocycles 41   2795 - 2798   1995.12Trichilinins B and C, two new limonoids from Melia toosendanReviewed

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  • Okamura Hiroaki, Iwagawa, Tetsuoetsuo, Nakatani, Munehiro .  A revised structure of chloranthalactone F and chloranthalactone A., photodimer .  Bull. Chem. Soc. Jpn.68   3465 - 3467   1995.12A revised structure of chloranthalactone F and chloranthalactone A., photodimerReviewed

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  • Nakatani, Munehirounehiro, Huang, RC., Okamura Hiroaki, Iwagawa, Tetsuoetsuo, Tadera, K .  SALANNAL, A NEW LIMONOID FROM MELIA AZEDARACH LINN .  Chem. Lett.   995 - 996   1995.11SALANNAL, A NEW LIMONOID FROM MELIA AZEDARACH LINNReviewed

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  • Nakatani, Munehirounehiro, Huang, RC., Okamura Hiroaki, Iwagawa, Tetsuoetsuo, Tadera, K., Naoki, H .  THREE NEW ANTIFEEDING MELIACARPININS FROM CHINESE MELIA-AZEDARACH LINN .  Tetrahedron 51   11731 - 11736   1995.10THREE NEW ANTIFEEDING MELIACARPININS FROM CHINESE MELIA-AZEDARACH LINNReviewed

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  • Okamura Hiroaki, Iwagawa, Tetsuoetsuo, Nakatani, Munehiro .  A BASE-CATALYZED DIELS-ALDER REACTION OF 3-HYDROXY-2-PYRONE .  Tetrahedron Lett.36   5939 - 5942   1995.8A BASE-CATALYZED DIELS-ALDER REACTION OF 3-HYDROXY-2-PYRONEReviewed

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  • Iwagawa, Tetsuoetsuo, Nakamura , S., Masuda, T., Okamura Hiroaki, Nakatani, Munehirounehiro, Shiro, M. .  IRREGULAR CEMBRANOIDS CONTAINING A 13-MEMBERED CARBOCYCLIC SKELETON., ISOLATED FROM A SOFT CORAL, SARCOPHYTON SPECIES .  Tetrahedron 51   5291 - 5298   1995.5IRREGULAR CEMBRANOIDS CONTAINING A 13-MEMBERED CARBOCYCLIC SKELETON., ISOLATED FROM A SOFT CORAL, SARCOPHYTON SPECIESReviewed

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  • HUANG, RC., Okamura Hiroaki, Iwagawa, Tetsuoetsuo, TADERA, K., Nakatani, Munehiro .  AZEDARACHIN-C, A LIMONOID ANTIFEEDANT FROM MELIA-AZEDARACH .  Phytochemistry 38   593 - 594   1995.2AZEDARACHIN-C, A LIMONOID ANTIFEEDANT FROM MELIA-AZEDARACHReviewed

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  • Iwagawa, Tetsuoetsuo, Shibata Yasushi., Okamura Hiroaki, Nakatani, Munehirounehiro, Shiro, M. .  NOVEL CEMBRANOIDS WITH A 13-MEMBERED CARBOCYCLIC SKELETON FROM A SOFT., CORAL, SARCOPHYTON SPECIES .  Tetrahedron Lett.35   8415 - 8416   1994.11NOVEL CEMBRANOIDS WITH A 13-MEMBERED CARBOCYCLIC SKELETON FROM A SOFT., CORAL, SARCOPHYTON SPECIESReviewed

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  • Nakatani, Munehirounehiro, Zhou, JB., Iwagawa, Tetsuoetsuo, Okamura, Hiroaki .  ISOLATION OF 2 LIMONOID ANTIFEEDANTS FROM MELIA-TOOSENDAN .  Heterocycles 38   2407 - 2410   1994.11ISOLATION OF 2 LIMONOID ANTIFEEDANTS FROM MELIA-TOOSENDANReviewed

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  • Huanng, RC., Okamura Hiroaki, Iwagawa, Tetsuoetsuo, Nakatani, Munehiro .  THE STRUCTURES OF AZEDARACHINS, LIMONOID ANTIFEEDANTS FROM CHINESE., MELIA-AZEDARACH LINN .  Bull. Chem. Soc. Jpn.67   2468 - 2472   1994.9THE STRUCTURES OF AZEDARACHINS, LIMONOID ANTIFEEDANTS FROM CHINESE., MELIA-AZEDARACH LINNReviewed

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  • Okamura Hiroaki, Nakashima Nobuyuki, Iwagawa, Tetsuoetsuo, Nakayama Noriyuki., Nakatani, Munehiro .  THE STRUCTURES OF 2 LINDENANE SESQUITERPENE GLUCOSIDES FROM CHLORANTHUS., GLAB .  Chem. Lett.   1541 - 1542   1994.8THE STRUCTURES OF 2 LINDENANE SESQUITERPENE GLUCOSIDES FROM CHLORANTHUS., GLABReviewed

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  • Nakatani, Munehirounehiro, Huanng, RC, Okamura Hiroaki, Naoki, H., Iwagawa, Tetsuo .  LIMONOID ANTIFEEDANTS FROM CHINESE MELIA-AZEDARACH .  Phytochemistry 36   39 - 41   1994.5LIMONOID ANTIFEEDANTS FROM CHINESE MELIA-AZEDARACHReviewed

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  • Nakatani, Munehirounehiro, ARIKAWA, S., Okamura Hiroaki, Iwagawa, Tetsuo .  ISOLATION OF A NEW INSECT ANTIFEEDING AZADIRACHTIN DERIVATIVE FROM., OKINAWAN MELIA-AZEDARACH LINN .  Heterocycles 38   327 - 331   1994.2ISOLATION OF A NEW INSECT ANTIFEEDING AZADIRACHTIN DERIVATIVE FROM., OKINAWAN MELIA-AZEDARACH LINNReviewed

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  • Nakatani, Munehirounehiro, Huanng, RC., Okamura Hiroaki, Iwagawa, Tetsuo .  THE STRUCTURE OF A NEW ANTIFEEDING MELIACARPININ FROM CHINES., MELIA-AZEDARACH-L .  Chem. Lett.   2125 - 2128   1993.12THE STRUCTURE OF A NEW ANTIFEEDING MELIACARPININ FROM CHINES., MELIA-AZEDARACH-LReviewed

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  • Okamura Hiroaki, Kuroda Satoru, Ikegami Satoshi, Tomita Kenji, Sugimoto Yuich, Sagaguchi Seiji, Ito Yuji, Katsuki Tsutomu, Yamagushi Masaru .  A FORMAL SYNTHESOF APLYSIATOXIN - ENANTIOSELECTIVE SYNTHESOF., KISHI ALDEHYDE .  Tetrahedron 49   10531 - 10554   1993.11A FORMAL SYNTHESOF APLYSIATOXIN - ENANTIOSELECTIVE SYNTHESOF., KISHI ALDEHYDEReviewed

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  • Ikegami Satoru, Okamura Hiroaki, Kuroda Satoshi, Katsuki Tsutomu, Yamagushi Masaru .  STEREOSELECTIVE SYNTHESOF (+/-)-IRELAND ALCOHOL USING., TITANIUM-MEDIATED [2,3]WITTIG REARRANGEMENT PRODUCT AS A STARTING., MATERIAL .  Bull. Chem. Soc. Jpn.65   1841 - 1848   1992.7STEREOSELECTIVE SYNTHESOF (+/-)-IRELAND ALCOHOL USING., TITANIUM-MEDIATED [2,3]WITTIG REARRANGEMENT PRODUCT AS A STARTING., MATERIALReviewed

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  • Itou, Katsuji, Kimura, Yuichi, Okamura Hiroaki, Katsuki Tsutomu .  ENANTIOSELECTIVE ADDITION OF DIETHYLZINC TO ALDEHYDES IN THE PRESENCE., OF CHIRAL TITANIUM REAGENT MODIFIED WITH N-SULFONYLATED AMINO ALCOHOL .  Synlett.   573 - 574   1992.7ENANTIOSELECTIVE ADDITION OF DIETHYLZINC TO ALDEHYDES IN THE PRESENCE., OF CHIRAL TITANIUM REAGENT MODIFIED WITH N-SULFONYLATED AMINO ALCOHOLReviewed

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  • Okamura Hiroaki, Kuroda Satoru, Ikegami Satoshi, Sugimoto Yuich, Sagaguchi Seiji, Ito Yuji, Katsuki Tsutomu, Yamagushi Masaru .  SYNTHESOF APLYSIATOXIN - STEREOSELECTIVE SYNTHESOF KEY FRAGMENTS .  Tetrahedron Lett.32   5137 - 5140   1991.9SYNTHESOF APLYSIATOXIN - STEREOSELECTIVE SYNTHESOF KEY FRAGMENTSReviewed

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  • Okamura Hiroaki, Kuroda Satoru, Ikegami Satoshi, Ito Yuji, Katsuki Tsutomu, Yamagushi Masaru .  A FORMAL TOTAL SYNTHESOF APLYSIATOXIN .  Tetrahedron Lett.32   5141 - 5142   1991.9A FORMAL TOTAL SYNTHESOF APLYSIATOXIN Reviewed

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MISC

  • カルバ糖 Reviewed

    岡村浩昭

    有機合成化学協会誌   70 ( 3 )   285 - 285   2012.3

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Presentations

  • 西村直樹,濱田季之,鬼束聡明,岡村浩昭   N-Boc-3-ヒドロキシ-2-ピリドンの合成及び塩基触媒 Diels-Alder 反応への応用  

    第53回複素環化学討論会  2024.10 

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    Event date: 2024.10

    Language:Japanese  

  • R. Takegawa, S. Onitsuka, T. Hamada, J. Kurawaki, H. Okamura   Spontaneous Formation of Gold Glyconanoparticles by Direct Reaction of ω-Glycosilated Alkylsulfanylanilines and HAuCl4   International conference

    17th International Symposium on Small Particles and Inorganic Clusters (ISSPIC-XVII)  17th International Symposium on Small Particles and Inorganic Clusters (ISSPIC-XVII)

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    Event date: 2014.9

    Language:English  

    Venue:福岡  

    国際学会

  • 岡村浩昭   塩基触媒Diels-Alder反応を利用した有機合成  

    第57回香料・精油・テルペン化学に関する討論会  第57回香料・精油・テルペン化学に関する討論会

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    Event date: 2013.10

    Language:Japanese  

    Venue:埼玉  

    国内学会

  • 岡村浩昭,置鮎佑太,竹川竜一,蔵脇淳一   金ナノ粒子表面上に機能性分子のみを高度に集積する方法の開発  

    ナノ学会第11回大会  ナノ学会第11回大会

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    Event date: 2013.5

    Language:Japanese  

    Venue:東京  

    国内学会

  • 置鮎佑太、岡村浩昭、蔵脇淳一、岩川哲夫、濱田季之   単糖および二糖-金ナノ粒子複合体の一段階調製法の開発  

    第92回日本化学会年会  第92回日本化学会年会

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    Event date: 2012.3

    Language:Japanese  

    Venue:神奈川  

    国内学会

  • 三原侑一郎、岡村浩昭、蔵脇淳一、岩川哲夫、濱田季之   PEG-ベンゼンチオール界面活性剤のミセル形成を利用した金ナノ粒子の調製  

    第92回日本化学会年会  第92回日本化学会年会

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    Event date: 2012.3

    Language:Japanese  

    Venue:神奈川  

    国内学会

  • 江崎寛輝、岡村浩昭、濱田季之、岩川哲夫   3-ヒドロキシ-2-ピロンの塩基触媒Diels-Alder反応を鍵反応とするcarba-pyranose類の不斉合成  

    第41回複素環化学討論会  第41回複素環化学討論会

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    Event date: 2011.10

    Language:Japanese  

    Venue:熊本  

    国内学会

  • 小柳祐二、岡村浩昭、濱田季之、岩川哲夫   3-ヒドロキシ-2-ピロンの塩基触媒Diels-Alder反応を鍵反応としたAmpelomin類およびGabosine類の不斉合成  

    第41回複素環化学討論会  第41回複素環化学討論会

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    Event date: 2011.10

    Language:Japanese  

    Venue:熊本  

    国内学会

  • 岡村浩昭、蔵脇淳一   ベンゼンチオール誘導体を利用した金ナノ粒子の簡便な調製法の開発  

    ナノ学会第9回大会  ナノ学会第9回大会

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    Event date: 2011.6

    Language:Japanese  

    Venue:北海道  

    国内学会

  • 置鮎 佑太・岡村 浩昭・蔵脇 淳一・濱田 季之・岩川 哲夫   糖を含む還元性安定化剤を用いた糖 - 金ナノ粒子複合体の一段階合成法  

    日本化学会第91春季年会(2011)  日本化学会第91春季年会(2011)

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    Event date: 2011.3

    Language:Japanese  

    Venue:日本、神奈川  

    国内学会

  • 岡村浩昭   依頼講演 カルバ糖類縁体の立体選択的合成  

    2010年日本化学会西日本大会  2010年日本化学会西日本大会

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    Event date: 2010.11

    Language:Japanese  

    Venue:日本、熊本  

    国内学会

  • 西 一駿、宮内奈緒美、岡村浩昭、岩川哲夫、濵田季之   奄美大島近海産ツブツブコイボウミウシPhyllidiopsisfissuratus に含まれる生物活性物質  

    2010年日本化学会西日本大会  2010年日本化学会西日本大会

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    Event date: 2010.11

    Language:Japanese  

    Venue:日本、熊本  

    国内学会

  • 前田祐一、岡村浩昭、岩川哲夫、濱田季之   奄美大島産海綿由来の生物活性物質の探索  

    2010年日本化学会西日本大会  2010年日本化学会西日本大会

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    Event date: 2010.11

    Language:Japanese  

    Venue:日本、熊本  

    国内学会

  • 山下雅史、岡村浩昭、岩川哲夫、濵田季之   日本近海産海洋無脊椎動物由来の生物活性物質の探索  

    2010年日本化学会西日本大会  2010年日本化学会西日本大会

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    Event date: 2010.11

    Language:Japanese  

    国内学会

  • 瀬座義哉、岡村浩昭、濱田季之、岩川哲夫   シクロヘキサジエノン由来の新規キラルビルディングブロックの開発  

    2010年日本化学会西日本大会  2010年日本化学会西日本大会

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    Event date: 2010.11

    Language:Japanese  

    国内学会

  • 江崎寛輝、岡村浩昭、濱田季之、岩川哲夫   塩基触媒Diels-Alder 反応を鍵反応とするcarbapyranose 類の不斉合成  

    2010年日本化学会西日本大会  2010年日本化学会西日本大会

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    Event date: 2010.11

    Language:Japanese  

    Venue:日本、熊本  

    国内学会

  • 小柳祐二、岡村浩昭、濱田季之、岩川哲夫   塩基触媒Diels-Alder 反応を用いたGabosine 類およびAmpelomin 類の不斉合成  

    2010年日本化学会西日本大会  2010年日本化学会西日本大会

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    Event date: 2010.11

    Language:Japanese  

    Venue:日本、熊本  

    国内学会

  • 石田拓也、是松季公子、Kwati Leonard、岡村弘昭、蔵脇 淳   新奇な樹状分子デンドロンを用いた金ナノ粒子・金ナノロッドの創製   International conference

    2010年日本化学会西日本大会  2010年日本化学会西日本大会

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    Event date: 2010.11

    Language:English  

    Venue:日本、熊本  

    国際学会

  • 置鮎 佑太・岡村 浩昭・蔵脇 淳一・濱田 季之・岩川 哲夫   ジヒドロキシ脂肪酸由来の還元性安定化剤を利用した金ナノ粒子の簡便な調製法の開発  

    2010年日本化学会西日本大会  2010年日本化学会西日本大会

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    Event date: 2010.11

    Language:Japanese  

    Venue:日本、熊本  

    国内学会

  • 瀬座義哉、岡村浩昭   塩基触媒Diels-Alder反応を用いた生理活性化合物の効率的合成法の開発  

    第20回万有シンポジウム福岡  第20回万有シンポジウム福岡

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    Event date: 2010.5

    Language:Japanese  

    Venue:日本、福岡  

    国内学会

  • Kwati Leonard, 蔵脇淳一, 岡浩昭, 川島正毅,秋山 毅,山田 淳   新規な金ナノ粒子/ジヒドロキシ脂肪酸由来デンドロン複合体の創製とキャラクタリゼーション  

    第8回ナノ学会  第8回ナノ学会

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    Event date: 2010.5

    Language:Japanese  

    Venue:日本、愛知  

    国内学会

  • 喜納兼吾、岡村浩昭   塩基触媒Diels-Alder反応を利用したシクロヘキセンオキシド類の合成研究  

    第44回化学関連支部合同九州大会  第44回化学関連支部合同九州大会

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    Event date: 2007.7

    Language:Japanese  

    Venue:福岡  

    国内学会

  • 田代順也、田中綾子、岡村浩昭   スルホキシイミンをリンカーとするpseudo-ペプチドの合成  

    第44回化学関連支部合同九州大会  第44回化学関連支部合同九州大会

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    Event date: 2007.7

    Language:Japanese  

    Venue:福岡  

    国内学会

  • Kipassa, N. T., 岡村浩昭, 岩川哲夫   塩基触媒Diels-Alder反応を利用したpseudo-アミノ糖の合成とタミフルの効率的な合成法の研究  

    第17回万有福岡シンポジウム  第17回万有福岡シンポジウム

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    Event date: 2007.5

    Language:Japanese  

    Venue:福岡  

    国内学会

  • 岡村浩昭   塩基触媒環化付加反応を利用した天然物合成  

    万有ミニシンポジウム長崎  万有ミニシンポジウム長崎

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    Event date: 2006.10

    Language:Japanese  

    Venue:長崎伊王島リゾート  

    国内学会

  • ○迫間ひとみ、岡村浩昭、岩川哲夫、中谷宗弘   ロジウム触媒を用いたスルフィドおよびスルホキシドのイミノ化反応  

    第85回日本化学会年会  第85回日本化学会年会

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    Event date: 2005.3

    Language:Japanese  

    Venue:神奈川大学  

    国内学会

  • 岡村浩昭   ロジウム触媒を用いたスルフィドおよびスルホキシドのイミノ化反応  

    日本化学会  日本化学会

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    Event date: 2005.3

    Language:Japanese  

    Venue:日本  

    国内学会

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Research Projects

  • 抗菌・防かび・抗ウイルス性を付与できる画期的塗布剤の開発~酸化亜鉛ナノ粒子上への抗菌剤の集積化による機能強化と物性の改良

    2019.9 - 2020.8

    政府機関  一般受託研究 

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    塗るだけで抗菌・防かび・抗ウイルス性を付与できる塗布剤の開発を行う。抗菌・防かび・抗ウイルス性のポリヘキサメチレンビグアニド(PHMB)-酸化亜鉛ナノ粒子複合体を塗料等に添加することで、使途の広い機能性塗布剤とする。