Updated on 2025/10/15

写真a

 
MISUMI Wakako
 
Organization
Research Field in Veterinary Medicine, Agriculture, Fisheries and Veterinary Medicine Area Joint faculty of Veterinary Medicine Assistant Professor
Title
Assistant Professor

Degree

  • Doctor of Veterinary Medicine ( 2025.3   Kagoshima University )

Research Interests

  • 薬剤耐性菌

  • 家畜の細菌性疾病

  • 細菌学

  • 家畜衛生学

Research Areas

  • Life Science / Veterinary medical science

Education

  • Rakuno Gakuen University

    2008.4 - 2014.3

Research History

  • Kagoshima University   Assistant Professor

    2025.8

  • 鹿児島県   曽於家畜保健衛生所   技術主査

    2022.4 - 2025.7

  • 鹿児島県   鹿児島中央家畜保健衛生所   獣医務技師

    2016.4 - 2022.3

  • 鹿児島県   姶良家畜保健衛生所   獣医務技師

    2014.4 - 2016.3

Professional Memberships

  • 日本細菌学会

    2017.10

  • 日本獣医学会

    2017.5

Qualification acquired

  • Veterinarian

 

Papers

  • Misumi W., Magome A., Okuhama E., Uchimura E., Tamamura-Andoh Y., Watanabe Y., Kusumoto M. .  CTX-M-55-type ESBL-producing fluoroquinolone-resistant Escherichia coli sequence type 23 repeatedly caused avian colibacillosis in Kagoshima Prefecture, Japan .  Journal of Global Antimicrobial Resistance35   325 - 331   2023.12Reviewed International journal

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    Authorship：Lead author   Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：Journal of Global Antimicrobial Resistance  

    Objectives: The production of expanded-spectrum beta-lactamases (ESBLs) and fluoroquinolone resistance in Enterobacteriaceae has become a global concern. The aim of this study was to investigate the spread of ESBL-producing and fluoroquinolone-resistant avian pathogenic Escherichia coli (APEC) in Kagoshima, a prefecture with the largest amount of poultry in Japan. Methods: The antimicrobial susceptibility and genetic characteristics of 228 APEC strains isolated from 57 farms in Kagoshima Prefecture, Japan, between 2005 and 2017 were analysed. Information about the companies with hatcheries connected to the farms was also collected, and the epidemiologic relatedness of APEC strains and the processes of adopting chicks were compared. Results: Seven CTX-M-type ESBL genes, bla<inf>CTX-M-1</inf>, bla<inf>CTX-M-2</inf>, bla<inf>CTX-M-14</inf>, bla<inf>CTX-M-15</inf>, bla<inf>CTX-M-25</inf>, bla<inf>CTX-M-55</inf>, and bla<inf>CTX-M-65</inf>, were found in 60 (26.3%) of the 228 APEC strains. The ciprofloxacin-resistant strains belonged to 10 different sequence types (ST10, ST23, ST93, ST155, ST156, ST350, ST359, ST602, ST648, and ST9479), and the two ST602 strains showed remarkably high ciprofloxacin resistance (MIC: 128 µg/mL) and had amino acid mutations in GyrA (S83L and D87N), ParC (S80I), and ParE (E460A). A CTX-M-55-type ESBL-producing fluoroquinolone-resistant Og78-ST23 strain was isolated multiple times over two years on a farm. Furthermore, epidemiologically closely related strains were isolated from different farms that used the same common hatcheries. Conclusions: APEC is often transferred from hatcheries to farms via healthy chicks, and the prudent use of antimicrobials and careful monitoring of resistant strains on poultry farms and hatcheries are important in preventing the selection and spread of high-risk APEC strains such as CTX-M-55-type ESBL-producing Og78-ST23.

    DOI： 10.1016/j.jgar.2023.10.015

    Scopus

  • Misumi Wakako, Funamori Taruho, Hamada Kyohei, Iwamoto Jiro, Fujisono Shoichiro, Chitose Kenichi, Kusumoto Masahiro .  Association between antimicrobial treatment and resistance of pathogenic Escherichia coli isolated from diseased swine in Kagoshima Prefecture, Japan .  The Journal of Veterinary Medical Science83 ( 3 ) 358 - 369   2021.3Reviewed

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    Language：English  

  • 猜都勇介、北原尚英、三角和華子、伊藤弘貴、松林誠、笹井和美、芝原友幸 .  子豚の小腸及び大腸パラフィン包埋切片を用いたTritrichomonas foetusの遺伝子学的同定及び粘膜固有層への侵入の特徴 .  日本獣医師会雑誌73 ( 8 ) 449 - 456   2020.9Reviewed

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  • Wakako Misumi, Daisuke Okada, Yoshimasa Hirashima, Shoichiro Fujisono, Masahiro Kusumoto .  Helcococcus kunzii Isolated from an Aborted Bovine Fetus .  Journal of the Japan Veterinary Medical Association72 ( 11 ) 686 - 690   2019.12Reviewed

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    Authorship：Lead author,　Corresponding author   Language：Japanese   Publishing type：Research paper (scientific journal)  

    DOI： 10.12935/jvma.72.686

  • Ueno Y, Teratani C, Misumi W, Hoshinoo K, Takamatsu D, Tagawa Y, Katsuda K. .  A Predominant Clonal Thromboembolic Meningoencephalitis Group of Histophilus somni Assigned by Major Outer Membrane Protein Gene Sequencing and Pulsed-Field Gel Electrophoresis .  Frontiers in Veterinary Science5   221 - 221   2018.9Reviewed International journal

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  • Wakako Misumi, Toshifumi Fukushima, Tadatsune Okuno, Yoshimasa Hirashima, Shoichiro Fujisono, Taketoshi Iwata .  Survey of the spread of Brachyspira hyodysenteriae in pigs and the environment of a pig farm in Kagoshima .  Brachyspira8 ( 1 ) 16 - 29   2018.6Reviewed

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    Authorship：Lead author,　Corresponding author   Language：Japanese   Publishing type：Research paper (scientific journal)  

  • Yuichi Ueno, Emi Yoshida, Wakako Misumi, Eri Watando, Kenta Suzuki, Yuko Hirai, Masatoshi Okura, Makoto Osaki, Ken Katsuda, Daisuke Takamatsu .  Population structure and antimicrobial susceptibility of Paenibacillus larvae isolates from American foulbrood cases in Apis mellifera in Japan .  Environmental Microbiology Reports10 ( 2 ) 210 - 216   2018.2Reviewed International journal

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1111/1758-2229.12623

  • Wakako Misumi, Yoko Tanaka, Shoichi Shibata, Takeshi Onitsuka and Kenshi Matsud .  Control of Dermanyssus gallinae Infestation with Cardboard Traps and the Susceptibility of the Mites to Acaricide .  Journal of the Japanese Society on Poultry Diseases52 ( 2 ) 106 - 110   2016.8Reviewed

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    Authorship：Lead author,　Corresponding author   Language：Japanese   Publishing type：Research paper (conference, symposium, etc.)  

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Awards

  • 九州地区学会長賞

    2018.10   日本獣医師会  

  • 大会長賞

    2018.7   ブラキスピラ学会  

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    Award type：Award from Japanese society, conference, symposium, etc. 

  • 優秀発表賞

    2015.10   鶏病研究会  

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    Award type：Award from Japanese society, conference, symposium, etc.