Updated on 2025/03/11

写真a

 
KONDO Mitsuki
 
Organization
Research Field in Veterinary Medicine, Agriculture, Fisheries and Veterinary Medicine Area Joint faculty of Veterinary Medicine Joint Department of Veterinary Medicine Assistant Professor
Title
Assistant Professor
Contact information
メールアドレス

Degree

  • ph. D ( Hokkaido University )

Research Interests

  • Xenobiotic metabolism

  • Toxicology

  • Wildlife toxicology

  • Comparative genomics

  • Genomics

Research History

  • National Institute for Environmental Studies   Biodiversity Division   Research associate

    2023 - 2024

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    Country：Japan

 

Papers

  • KONDO Mitsuki, ONUMA Manabu, NAKAYAMA Shouta M. M., OOTAWA Tomoki, ISHIZUKA Mayumi .  Current situation of lead (Pb) pollution of wild bird in Japan, focusing on wild waterfowls .  Annual Meeting of the Japanese Society of Toxicology51.1 ( 0 ) S15-2   2024

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    Language：Japanese   Publisher：The Japanese Society of Toxicology  

    <p>Lead contamination is currently a serious environmental pollution problem for wild birds. Ingestion of lead from the use of lead shotgun bullets and lead fishing tackles has been reported to cause lead pollution in various bird species worldwide, including Japan. Lead poisoning is known to cause neurological, anemia, and gastrointestinal symptoms as acute toxicity, as well as kidney damage, immunodeficiency, and reproductive disorders as chronic and sub-chronic effects. In particular, the immunodeficiency caused by lead should be considered in relation to the spread of avian influenza, of which birds are natural hosts, and should be addressed on a global scale to prevent the spread of infectious diseases. In addition, it is necessary to accurately understand the toxic effects of lead contamination, especially in species such as wild birds, where reproductive disorders and immunodeficiency can significantly reduce population size and thus have strong impact the ecosystem. While it is important to target rare and potentially important species of raptors in actual monitoring of lead contamination in wild birds, national monitoring is insufficient due to the limited sample size and regional restrictions. Therefore, monitoring of lead contamination in waterfowl such as ducks, which are relatively common throughout Japan and for which samples are easily obtained, will be useful in understanding the contamination status of wild birds. Based on this situation, we are currently analyzing organ lead concentrations in wild birds, especially waterfowl, as a foothold for accurate understanding of the toxic effects of lead contamination. In this presentation, we would like to share the current status of lead contamination in wild birds, the start-up of this project that began last fiscal year, the current status, and future prospects.</p>

    DOI： 10.14869/toxpt.51.1.0_s15-2

    CiNii Research

  • Watanabe K, Kondo M, Ikenaka Y, Nakayama SMM, Ishizuka M .  A Comparative Genomic and Phylogenetic Investigation of the Xenobiotic Metabolism Enzymes of Cytochrome P450 in Elephants Shows Loss in CYP2E and CYP4A. .  Animals : an open access journal from MDPI13 ( 12 )   2023.6Reviewed

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.3390/ani13121939

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  • Shinya S, Kawai Y, Kondo M, Nakayama SMM, Ishizuka M, Ikenaka Y .  Characteristics of cytochrome P450-dependent metabolism against acetamiprid in the musk shrew (Suncus murinus). .  Comparative biochemistry and physiology. Toxicology & pharmacology : CBP265   109537   2023.3Reviewed

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1016/j.cbpc.2022.109537

    PubMed

  • Kondo M, Ikenaka Y, Nakayama SMM, Kawai YK, Mizukawa H, Mitani Y, Nomyama K, Tanabe S, Ishizuka M .  Sulfotransferases (SULTs), enzymatic and genetic variation in Carnivora: Limited sulfation capacity in pinnipeds. .  Comparative biochemistry and physiology. Toxicology & pharmacology : CBP263   109476   2023.1Reviewed

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1016/j.cbpc.2022.109476

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  • Kondo M, Ikenaka Y, Nakayama SMM, Kawai YK, Ishizuka M .  Duplication, Loss, and Evolutionary Features of Specific UDP-Glucuronosyltransferase Genes in Carnivora (Mammalia, Laurasiatheria). .  Animals : an open access journal from MDPI12 ( 21 )   2022.10Reviewed

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.3390/ani12212954

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  • Kondo M, Ikenaka Y, Nakayama SMM, Kawai YK, Ishizuka M .  Specific Gene Duplication and Loss of Cytochrome P450 in Families 1-3 in Carnivora (Mammalia, Laurasiatheria). .  Animals : an open access journal from MDPI12 ( 20 )   2022.10Reviewed

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.3390/ani12202821

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  • Kawai YK, Shinya S, Ikenaka Y, Saengtienchai A, Kondo M, Darwish WS, Nakayama SMM, Mizukawa H, Ishizuka M .  Characterization of function and genetic feature of UDP-glucuronosyltransferase in avian species. .  Comparative biochemistry and physiology. Toxicology & pharmacology : CBP217   5 - 14   2019.3Reviewed

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1016/j.cbpc.2018.11.001

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  • Saengtienchai A, Ikenaka Y, Kawata M, Kawai Y, Takeda K, Kondo M, Bortey-Sam N, Nakayama SMM, Mizukawa H, Ishizuka M .  Comparison of xenobiotic metabolism in phase I oxidation and phase II conjugation between rats and bird species. .  Comparative biochemistry and physiology. Toxicology & pharmacology : CBP214   28 - 35   2018.12

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    Language：English  

    DOI： 10.1016/j.cbpc.2018.08.007

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  • Mitsuki Kondo, Yoshinori Ikenaka, Shouta M. M. Nakayama, Yusuke K. Kawai, Hazuki Mizukawa, Yoko Mitani, Kei Nomiyama, Shinsuke Tanabe, Mayumi Ishizuka .  Uridine Diphosphate-Glucuronosyltransferase (UGT) 2B Subfamily Interspecies Differences in Carnivores .  Toxicological Sciences158 ( 1 ) 90 - 100   2017.4Reviewed International coauthorship

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    Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

    DOI： https://doi.org/10.1093/toxsci/kfx072

  • Yoshiya Yamamura, Shintaro Nakagawa, Mitsuki Kondo, So Shinya, Rio Doya, Masashi Koide, Yared Beyene Yohannes, Yoshinori Ikenaka, Mayumi Ishizuka ,Shouta M. M. Nakayama .  Anticoagulant rodenticides exposure status among wild pit vipers (Protobothrops flavoviridis) and green anoles (Anolis carolinensis) in two Japanese Islands .  European Journal of Wildlife Research70 ( 57 )   2024.5Reviewed

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： https://doi.org/10.1007/s10344-024-01812-4

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MISC

  • ゲノム情報から探る“解毒“酵素の進化と種差 Invited

    近藤　充希

    日本内分泌かく乱物質学会　ニュースレター   27 ( 1 )   6 - 7   2024.6

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    Authorship：Lead author   Language：Japanese   Publishing type：Article, review, commentary, editorial, etc. (scientific journal)  

Presentations

  • 森田 鮎子, 近藤 充希, 渡邉 可菜実, 池中 良徳, 中山 翔太, 石塚 真由美   アジアゾウとアフリカゾウにおけるエタノール及びアシクロビルの代謝能　アルコール脱水素酵素の遺伝学的比較解析からの考察  

    日本野生動物医学会誌  2023.12  日本野生動物医学会

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    Language：Japanese  

  • 近藤 充希, 池中 良徳, 中山 翔太, 川合 佑典, 石塚 真由美   食肉目(Mammalia, Laurasiatheria)のCYP450 1-3ファミリーにおける特異的進化的特徴、特異的遺伝子の消失、重複について(Carnivora(Mammalia,Laurasiatheria) specific evolutional features and specific gene loss and duplication and in CYP450 1-3 families)  

    The Journal of Toxicological Sciences  2022.6  (一社)日本毒性学会

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    Language：Japanese  

  • 石塚 真由美, 近藤 充希, 池中 良徳, 中山 翔太   解毒の種差を探る　解毒酵素の動物種差と進化  

    The Journal of Toxicological Sciences  2023.6  (一社)日本毒性学会

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    Language：Japanese  

  • 近藤 充希, 大沼 学, 中山 翔太, 大田和 朋紀, 石塚 真由美   日本における野生鳥類の鉛汚染の現状把握　水鳥を中心に用いたサーベイランス  

    日本野生動物医学会誌  2023.12  日本野生動物医学会

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    Language：Japanese  

  • 銅谷 理緒, 中山 翔太, 中田 北斗, 近藤 充希, Zyambo Golden, Muzandu Kaampwe, Yabe John, 池中 良徳, 石塚 真由美   土地利用方法に着目した野生トカゲの重金属汚染バイオモニタリング;ザンビア共和国の鉱山跡地を例として(Wild Lizards as a Target of Heavy Metal Biomonitoring Focusing on Land Use Patterns: An Example from a Former Mining Site in Zambia)  

    The Journal of Toxicological Sciences  2022.6  (一社)日本毒性学会

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    Language：English  

  • 新屋 惣, 川合 佑典, 近藤 充希, 中山 翔太, 石塚 真由美, 池中 良徳   スンクスにおけるアセタミプリド代謝の特徴  

    The Journal of Toxicological Sciences  2022.6  (一社)日本毒性学会

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    Language：Japanese  

  • 伊藤 愛真, 近藤 充希, 池中 良徳, 田中 亜紀, 下鶴 倫人, 佐鹿 万里子, 柳川 洋二郎, 笠松 雅彦, 角川 雅俊, 中山 翔太, 石塚 真由美   ステロイドホルモンおよびその抱合体化物の血中組成における動物種差  

    日本獣医学会学術集会講演要旨集  2022.9  (公社)日本獣医学会

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    Language：Japanese  

  • 石原 清伍, 中田 北斗, John Yabe, Andrew Kataba, Kaampwe Muzandu, Golden Zyambo, 本平 航大, 銅谷 理緒, Yared Yohannes, 近藤 充希, 一瀬 貴大, 池中 良徳, 石塚 真由美, 中山 翔太   ザンビアの鉛高濃度汚染地域と低濃度汚染地域における野生ラットの鉛蓄積量及び糖代謝関連遺伝子発現量の解析  

    日本獣医学会学術集会講演要旨集  2022.9  (公社)日本獣医学会

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    Language：Japanese  

  • 近藤 充希, 大沼 学, 中山 翔太, 大田和 朋紀, 石塚 真由美   鳥の鉛中毒:国内で「今」起きている健康被害　日本における野生水鳥を中心とした鳥類の鉛汚染状況の把握  

    The Journal of Toxicological Sciences  2024.7  (一社)日本毒性学会

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    Language：Japanese  

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