Life Science / Molecular biology

日本農芸化学会

2015.10

THE JAPANESE SOCIETY FOR IMMUNOLOGY

JAPANESE SOCIETY FOR BACTERIOLOGY

JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY

日本インターフェロン・サイトカイン学会

Sayaka Iizasa, Ei'ichi Iizasa, Keiichi Watanabe, Yukio Nagano .  Transcriptome analysis reveals key roles of AtLBR-2 in LPS-induced defense responses in plants .  BMC Genomics18 ( 1 ) 995   2017.12Transcriptome analysis reveals key roles of AtLBR-2 in LPS-induced defense responses in plants

Ei'ichi Iizasa, Takayuki Uematsu, Yasushi Chuma, Hideyasu Kiyohara, Mio Kutobta, Masayuki Umemura, Goro Matsuzaki, Sho Yamasaki, Hiromitsu Hara .  Two distinct ITAM-coupled receptors recognize mycobacterial mycolic acid-containing lipids and differently regulate immune responses .  CYTOKINE100   26 - 27   2017.12

Phongsisay V., Iizasa E., Hara H., and Yoshida Y. .  Pertussis toxin targets the innate immunity through DAP12, FcRγ, and MyD88 adaptor proteins. .  Immunobiology222 ( 4 ) 664 - 671   2017.4Pertussis toxin targets the innate immunity through DAP12, FcRγ, and MyD88 adaptor proteins.Reviewed

Vongsavanh Phongsisay, Ei'ichi Ilizasa, Hiromitsu Hara, Hiroki Yoshida .  Pertussis toxin targets the innate immunity through DAP12, FcR gamma, and MyD88 adaptor proteins .  IMMUNOBIOLOGY222 ( 4 ) 664 - 671   2017.4Pertussis toxin targets the innate immunity through DAP12, FcR gamma, and MyD88 adaptor proteins

Iizasa S., Iizasa E., Matsuzaki S., Tanaka H., Kodama Y., Watanabe K., and Nagano Y. .  Arabidopsis LBP/BPI related-1 and -2 bind to LPS directly and regulate PR1 expression .  Scientific reports   2016.6Arabidopsis LBP/BPI related-1 and -2 bind to LPS directly and regulate PR1 expressionReviewed

Uematsu T, Iizasa E, Kobayashi N, Yoshida H, Hara H. .  Loss of CARD9-mediated innate activation attenuates severe influenza pneumonia without compromising host viral immunity. .  Scientific reports   2015.12Loss of CARD9-mediated innate activation attenuates severe influenza pneumonia without compromising host viral immunity.Reviewed

永野幸生、飯笹英一 .  相同組換えで色々できちゃうDNAクローニング .  生物工学会誌   2015.10相同組換えで色々できちゃうDNAクローニングInvited Reviewed

Phongsisay V, Iizasa E, Hara H, Yoshida H. .  Evidence for TLR4 and FcRγ-CARD9 activation by cholera toxin B subunit and its direct bindings to TREM2 and LMIR5 receptors. .  molecular immunology   2015.5Evidence for TLR4 and FcRγ-CARD9 activation by cholera toxin B subunit and its direct bindings to TREM2 and LMIR5 receptors.Reviewed

Phongsisay V., Iizasa E., Hara H., and Yamasaki S. .  3-O-sulfo-β-d-galactose moiety of endogenous sulfoglycolipids is a potential ligand for immunoglobulin-like receptor LMIR5 .  Molecular immunology63 ( 2 ) 595 - 599   2015.23-O-sulfo-β-d-galactose moiety of endogenous sulfoglycolipids is a potential ligand for immunoglobulin-like receptor LMIR5Reviewed

Yasukawa S., Miyazaki Y., Yoshii C., Nakaya M., Ozaki N., Toda S., Kuroda E., Ishibashi K., Yasuda T., Natsuaki Y., Mi-ichi F., Iizasa E., Nakahara T., Yamazaki M., Kabashima K., Iwakura Y., Takai T., Saito T., Kurosaki T., Malissen B., Ohno N., Furue M., Yoshida H., and Hara H*. .  An ITAM-Syk-CARD9 signalling axis triggers contact hypersensitivity by stimulating IL-1 production in dendritic cells .  Nature Communications5   3755   2014An ITAM-Syk-CARD9 signalling axis triggers contact hypersensitivity by stimulating IL-1 production in dendritic cellsReviewed

Phongsisay V., Iizasa E., Hara H., and Yamasaki S .  LMIR5 extracellular domain activates myeloid cells through Toll-like receptor 4 .  Molecular immunology62   169 - 177   2014LMIR5 extracellular domain activates myeloid cells through Toll-like receptor 4Reviewed

Iizasa E., Mitsutomi M., and Nagano Y .  Direct binding of a plant LysM receptor-like kinase, LysM RLK1/CERK1, to chitin in vitro .  Journal of Biological Chemistry285   2996 - 3004   2010.1Direct binding of a plant LysM receptor-like kinase, LysM RLK1/CERK1, to chitin in vitroReviewed

Hara H.,Iizasa E., Nakaya M., and Yoshida H. .  L-CBM signaling in lymphocyte development and function, .  Journal of Blood Medicine1   93 - 104   2010.1L-CBM signaling in lymphocyte development and function,Reviewed

Nagano Y., Takao S., Kudo T., Iizasa E., and Anai T .  Yeast-based recombineering of DNA fragments into plant transformation vectors by one-step transformation .  Plant Cell Reports26   2111 - 2117   2007Yeast-based recombineering of DNA fragments into plant transformation vectors by one-step transformationReviewed

Iizasa E. and Nagano Y. .  Highly efficient yeast-based in vivo DNA cloning of multiple DNA fragments and the simultaneous construction of yeast/ Escherichia coli shuttle vectors .  Biotechniques40   75 - 83   2006.1Highly efficient yeast-based in vivo DNA cloning of multiple DNA fragments and the simultaneous construction of yeast/ Escherichia coli shuttle vectorsReviewed

飯笹 英一, 三山英夫, 豊永憲司, 原博満   ITAM-Card9経路のGM-CSF受容体シグナルへの関与  

第８４回インターフェロン・サイトカイン学会  2019.8 

Iizasa E, Uematsu T, Chuma Y, Kiyohara H, Kubota M, Umemura M, Matsuzaki G, Yamasaki S, Hara H   The function of a DAP12-associated receptor recognizing mycobacterial lipids  

日米医学協力計画 抗酸菌専門部会 第52回日米合同部会  2018.3 

Iizasa E, Uematsu T, Chuma Y, Kiyohara H, Kubota M, Umemura M, Matsuzaki G, Yamasaki S, Hara H   Two distinct ITAM-coupled receptors recognize mycobacterial mycolic acid-containing lipids and differently regulate immune responses  

The 5th Annual Meeting of the International Cytokine and Interferon Society  2017.10 

Iizasa E, Uematsu T, Chuma Y, Kiyohara H, Kubota M, Umemura M, Matsuzaki G, Yamasaki S, Hara H   Two ITAM-coupled receptors recognizing Mycobacterial mycolic acid-containing lipids and having the different roles  

The 46th Annual Meeting of the Japanese Society for Immunology  2017.12 

飯笹英一, 中馬康志, 植松崇之, 久保田未央, 川口博明, 梅村正幸, 豊永憲司, 清原秀泰, 矢野郁也, Marco Colonna, 杉田昌彦, 松崎吾朗, 山崎晶, 吉田裕樹, 原博満   TREM2は非糖鎖付加ミコール酸を認識し、マクロファージの抗酸菌免疫応答を抑制する  

第８５回日本インターフェロン・サイトカイン学会  2021.5 

〇 Ei'ichi Iizasa, Hideo Mitsuyama, Yuki Oyamada, Hiromasa Inoue, Hiromitsu Hara   Card9 is crucial for bone marrow-derived inflammatory macrophage differentiation induced by GM-CSF  

The 50th Annual Meeting of the Japanese Society for Immunology  2021.12 

Th2型免疫応答誘導に関わるキチン受容体およびシグナル分子の同定

2017.4 - 2019.3

日本学術振興会  科学研究費助成事業 若手研究B 

飯笹 英一

敗血症におけるTREM1Lの同定

2015.12 - 2017.12

GSKジャパン  GSKジャパン若手研究助成 

敗血症におけるTREM1リガンドの探索

2015.9 - 2017.3

グラクソ・スミスクライン株式会社  2015年度GSKジャパン研究助成 

飯笹 英一

哺乳類におけるキチン受容体の同定

2015.4 - 2016.3

民間財団等  笹川科学研究助成 

結核菌を認識する新規骨髄系ITAMRの同定

2014.4 - 2017.3

科学研究費補助金  若手研究(B)

自然免疫におけるCard9シグナル伝達経路の解明

2011.4 - 2014.3

科学研究費補助金  特別研究員(PD)研究奨励費

ロイシンリッチリピート受容体キナーゼとそのリガンドの相互作用機構の解明

2007.4 - 2010.3

科学研究費補助金  特別研究員(DC1)研究奨励費