Hiramoto H, Dansako H, Takeda M, Satoh S, Wakita T, Ikeda M, Kato N. .  Annexin A1 negatively regulates viral RNA replication of hepatitis C virus. .  Acta Medica Okayama69 ( 2 ) 71 - 78   2015.1Annexin A1 negatively regulates viral RNA replication of hepatitis C virus.Reviewed

Hara Y, Yanatori I, Ikeda M, Kiyokage E, Nishina S, Tomiyama Y, Toida K, Kishi F, Kato N, Imamura M, Chayama K, Hino K. .  Hepatitis C virus core protein suppr 1 esses mitophagy by interacting with Parkin in the context of mitochondrial depolarization. .  Amer J Pathol184 ( 11 ) 3026 - 3039   2014.1Hepatitis C virus core protein suppr 1 esses mitophagy by interacting with Parkin in the context of mitochondrial depolarization.Reviewed

Matsuno K, Ueda Y, Fukuda M, Onoda K, Waki M, Ikeda M, Kato N, Miyachi H .  Synthesis and inhibitory activity on hepatitis C virus RNA replication of 4-(1,1,1,3,3,3-hexafluoro-2-hydroxy-2-propyl)aniline analogs .  Bioorg Med Chem Lett.24 ( 17 ) 4276 - 4280   2014.1Synthesis and inhibitory activity on hepatitis C virus RNA replication of 4-(1,1,1,3,3,3-hexafluoro-2-hydroxy-2-propyl)aniline analogsReviewed

Dansako H, Hiramoto H, Ikeda M, Wakita T, Kato N. .  Rab18 is required for viral assembly of hepatitis C virus through trafficking of the core protein to lipid droplets .  Virology462-463   166 - 174   2014.1Rab18 is required for viral assembly of hepatitis C virus through trafficking of the core protein to lipid dropletsReviewed

Ueda Y, Mori K, Satoh S, Dansako H, Ikeda M, Kato N .  Anti-HCV activity of the Chinese medicinal fungus Cordyceps militaris .  Biochem Biophys Res Commun447 ( 2 ) 341 - 345   2014.1Anti-HCV activity of the Chinese medicinal fungus Cordyceps militarisReviewed

Kato N, Sejima H, Ueda Y, Mori K, Satoh S, Dansako H, Ikeda M. .  Genetic characterization of hepatitis C virus in long-term RNA replication using Li23 cell culture systems. .  PLoS ONE9 ( 3 ) e91156   2014.1Genetic characterization of hepatitis C virus in long-term RNA replication using Li23 cell culture systems.Reviewed

Shinohara Y, Imajo K, Yoneda M, Tomeno W, Ogawa Y, Fujita K, Kirikoshi H, Takahashi J, Funakoshi K, Ikeda M, Kato N, Nakajima A, Saito S .  Hepatic triglyceride lipase plays an essential role in changing the lipid metabolism in genotype 1b hepatitis C virus replicon cells and hepatitis C patients .  Hepatol. Res.43 ( 11 ) 1190 - 1198   2013.1Hepatic triglyceride lipase plays an essential role in changing the lipid metabolism in genotype 1b hepatitis C virus replicon cells and hepatitis C patientsReviewed

Tanaka T, Kuroda K, Ikeda M, Kato N, Shimizu K, Makishima M .  Direct targeting of proteins to lipid droplets demonstrated by time-lapse live cell imaging .  J Bioscience and Bioengineering116 ( 5 ) 620 - 623   2013.1Direct targeting of proteins to lipid droplets demonstrated by time-lapse live cell imagingReviewed

Shinohara Y, Imajo K, Yoneda M, Tomeno W, Ogawa Y, Kirikoshi H, Funakoshi K, Ikeda M, Kato N, Nakajima A, Saito S .  Unfolded protein response pathways regulate Hepatitis C virus replication via modulation of autophagy .  Biochem Biophys Res Commun432   326 - 332   2013.1Unfolded protein response pathways regulate Hepatitis C virus replication via modulation of autophagyReviewed

Mori K, Hiraoka O, Ikeda M, Ariumi Y, Hiramoto A, Wataya Y, Kato N .  Adenosine kinase is a key determinant for the anti-HCV activity of ribavirin .  Hepatology58 ( 4 ) 1236 - 1244   2013.1Adenosine kinase is a key determinant for the anti-HCV activity of ribavirinReviewed

Kuroki M, Ariumi Y, Hijikata M, Ikeda M, Dansako H, Wakita T, Shimotohno K, Kato N. .  PML tumor suppressor protein is required for HCV production .  Biochem. Biophys. Res. Commun430   592 - 597   2013.1PML tumor suppressor protein is required for HCV productionReviewed

Tanaka T, Kuroda K, Ikeda M, Wakita T, Kato N, Makishima M .  Hepatitis C virus NS4B targets lipid droplets through hydrophobic residues in the amphipathic helices .  J. Lipid Res54   881 - 892   2013.1Hepatitis C virus NS4B targets lipid droplets through hydrophobic residues in the amphipathic helicesReviewed

Sato A, Saito Y, Sugiyama K, Sakasegawa N, Muramatsu T, Fukuda S, Yoneya M, Kimura M, Ebinuma H, Hibi T, Ikeda M, Kato N, Saito H .  Suppressive effect of the histone deacetylase inhibitor, suberoylanilide hydroxamic acid (SAHA), on hepatitis C virus replication via epigenetic changes in host cells .  J. Cell. Biochem.114 ( 9 ) 1987 - 1996   2013.1Suppressive effect of the histone deacetylase inhibitor, suberoylanilide hydroxamic acid (SAHA), on hepatitis C virus replication via epigenetic changes in host cellsReviewed

Shen H, Yamashita A, Nakakoshi M, Yokoe H, Sudo M, Kasai H, Tanaka T, Fujimoto Y, Ikeda M, Kato N, Sakamoto N, Shindo H, Maekawa S, Enomoto N, Tsubuki M, Moriishi K .  Inhibitory effects of caffeic acid phenethyl ester derivatives on replication of hepatitis C virus .  PLoS ONE8 ( 12 ) e82299   2013.1Inhibitory effects of caffeic acid phenethyl ester derivatives on replication of hepatitis C virusReviewed

Ban S, Ueda Y, Ohashi M, Matsuno K, Ikeda M, Kato N, Miyachi H .  Peroxisome proliferator-activated receptor delta antagonists inhibit hepatitis C virus RNA replication .  Bioorg. Med. Chem. Letters23 ( 17 ) 4774 - 4778   2013.1Peroxisome proliferator-activated receptor delta antagonists inhibit hepatitis C virus RNA replicationReviewed

Ueda Y, Takeda M, Mori K, Dansako H, Wakita T, Kim HS, Sato A, Wataya Y, Ikeda M, Kato N .  New preclinical antimalarial drugs potently inhibit hepatitis C virus genotype 1b RNA replication .  PLoS ONE8 ( 8 ) e72519   2013.1New preclinical antimalarial drugs potently inhibit hepatitis C virus genotype 1b RNA replicationReviewed

Fujimoto Y, Salam KA, Furuta A, Matsuda Y, Fujita O, Tani H, Ikeda M, Kato N, Sakamoto N, MaekawaS, Enomoto N, de Voogd NJ, Nakakoshi M, Tsubuki M, Sekiguchi Y, Tsuneda S, Akimitsu N, Noda N, Yamashita A, Tanaka J, Moriishi K .  Inhibition of both protease and helicase activities of hepatitis 1 C virus NS3 by an ethyl acetate extract of marine sponge Amphimedon sp .  PLoS One7   e48685   2012.1Inhibition of both protease and helicase activities of hepatitis 1 C virus NS3 by an ethyl acetate extract of marine sponge Amphimedon spReviewed

Sejima H, Mori K, Ariumi Y, Ikeda M, Kato N .  Identification of host genes showing differential expression profiles with cell-based long-term replication of hepatitis C virus RNA .  Virus Res167 ( 1 ) 74 - 85   2012.1Identification of host genes showing differential expression profiles with cell-based long-term replication of hepatitis C virus RNAReviewed

Yamashita A, Salam KA, Furuta A, Matsuda Y, Fujita O, Tani H, Fujita Y, Fujimoto Y, Ikeda M, Kato N, Sakamoto N, Maekawa S, Enomoto N, Nakakoshi M, Tsubuki M, Sekiguchi Y, Tsuneda S, Akimitsu N, Noda N, Tanaka J, Moriishi K .  Inhibition of hepatitis C virus replication and viral helicase byethyl acetate extract of the marine feather star Alloeocomatella polycladia .  Mar. Drugs10   744 - 761   2012.1Inhibition of hepatitis C virus replication and viral helicase byethyl acetate extract of the marine feather star Alloeocomatella polycladiaReviewed

Takeda M, Ikeda M, Ariumi Y, Wakita T, Kato N. .  Development of hepatitis C virus production reporter assay systems using two different hepatoma cell lines .  J. Gen. Virol.93 ( 7 ) 1422 - 1431   2012.1Development of hepatitis C virus production reporter assay systems using two different hepatoma cell linesReviewed

Takeshita S, Ichikawa T, Taura N, Miyaaki H, Matsuzaki T, Otani M, Muraoka T, Akiyama M, Miuma S, Ozawa E, Ikeda M, Kato N, Isomoto H, Takeshima F, Nakao K .  Geranylgeranylacetone has anti-hepatitis C virus activity via activation of mTOR in human hepatoma cells .  J. Gastroenterol47 ( 2 ) 195 - 202   2012.1Geranylgeranylacetone has anti-hepatitis C virus activity via activation of mTOR in human hepatoma cellsReviewed

Iikura M, Furihata T, Mizuguchi M, Nagai M, Ikeda M, Kato N, Tsubota A, Chiba K .  ENT1, a ribavirin transporter, plays a pivotal role in antiviral efficacy of ribavirin in a hepatitis C virus replication cell system .  Antimicrob. Agents Chemother.56 ( 3 ) 1407 - 1413   2012.1ENT1, a ribavirin transporter, plays a pivotal role in antiviral efficacy of ribavirin in a hepatitis C virus replication cell systemReviewed

Mori K, Ueda Y, Ariumi Y, Dansako H, Ikeda M, Kato N .  Development of a drug assay system with hepatitis C virus genome derived from a patientwith acute hepatitis C .  Virus Genes44 ( 3 ) 374 - 381   2012.1Development of a drug assay system with hepatitis C virus genome derived from a patientwith acute hepatitis CReviewed

Takeda M, Ikeda M, Mori K, Yano M, Ariumi Y, Dansako H, Wakita T, Kato N .  Raloxifene inhibits hepatitis C virus infection and replication .  FEBS Open Bio2 ( 279 ) 283   2012.1Raloxifene inhibits hepatitis C virus infection and replicationReviewed