Organization
University Hospital, Medical and Dental Sciences Area University Hospital Clinical Facilities Clinical Laboratory Assistant Professor
Title
Assistant Professor
OYAMA Yoko
Research Areas
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Others / Others / 血管代謝病態解析学
Research History
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Kagoshima University Medical and Dental Hospital, Medical and Dental Sciences Area Medical and Dental Hospital Clinical Facilities Clinical Laboratory Assistant Professor
2003.4 - 2017.3
Professional Memberships
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日本感染症学会
2015.10
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日本乳癌学会
2015.10
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日本内科学会
2015.10
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日本臨床検査医学会
2015.10
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日本臨床検査専門医会
2015.10
Papers
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Sarikaphuti A, Nararatwanchai T, Hashiguchi T, Ito T, Thaworanunta S, Kikuchi K, Oyama Y, Maruyama I, Tancharoen S. . Preventive effects of Morus alba L. anthocyanins on diabetes in Zucker diabetic fatty rats. . Exp Ther Med.6 ( 3 ) 689 - 695 2013.9Reviewed
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Kikuchi K, Kawahara KI, Uchikado H, Miyagi N, Kuramoto T, Miyagi T, Morimoto Y, Ito T, Tancharoen S, Miura N, Takenouchi K, Oyama Y, Shrestha B, Matsuda F, Yoshida Y, Arimura S, Mera K, Tada KI, Yoshinaga N, Maenosono R, Ohno Y, Hashiguchi T, Maruyama I, Shigemori M. . Potential of edaravone for neuroprotection in neurologic diseases that do not involve cerebral infarction. . Exp Ther Med2 ( 5 ) 771 - 775 2011.6Reviewed
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Meng X, Kawahara KI, Miyanohara H, Yoshimoto Y, Yoshinaga K, Noma S, Kikuchi K, Morimoto Y, Ito T, Oyama Y, Yoshinaga N, Shrestha B, Chandan B, Mera K, Tada KI, Miura N, Ono Y, Takenouchi K, Maenosono R, Nagasato T, Hashiguchi T, Maruyama I. . 1,5-Anhydro-D-fructose: A natural antibiotic that inhibits the growth of gram-positive bacteria and microbial biofilm formation to prevent nosocomial infection. . Exp Ther Med2 ( 4 ) 625 - 628 2011.4Reviewed
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Kikuchi K, Kawahara KI, Miyagi N, Uchikado H, Kuramoto T, Morimoto Y, Tancharoen S, Miura N, Takenouchi K, Oyama Y, Shrestha B, Matsuda F, Yoshida Y, Arimura S, Mera K, Tada KI, Yoshinaga N, Maenosono R, Ohno Y, Hashiguchi T, Maruyama I, Shigemori M. . Edaravone: A new therapeutic approach for the treatment of acute stroke. . Med Hypotheses75 ( 6 ) 583 - 585 2010.8Reviewed
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Shrestha B, Hashiguchi T, Ito T, Miura N, Takenouchi K, Oyama Y, Kawahara K, Tancharoen S, Ki-I Y, Arimura N, Yoshinaga N, Noma S, Shrestha C, Nitanda T, Kitajima S, Arimura K, Sato M, Sakamoto T, Maruyama I. . B cell-derived vascular endothelial growth factor A promotes lymphangiogenesis and high endothelial venule expansion in lymph nodes. . J Immunol. 184 ( 9 ) 4819 - 4826 2010.1Reviewed
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Oyama Y, Hashiguchi T, Taniguchi N, Tancharoen S, Uchimura T, Biswas KK, Kawahara K, Nitanda T, Umekita Y, Lotz M, Maruyama I. . High-mobility group box-1 protein promotes granulomatous nephritis in adenine-induced nephropathy. . Lab Invest.90 ( 6 ) 853 - 866 2010.1Reviewed
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Saiwichai T, Sangalangkarn V, Kawahara K, Oyama Y, Chaichalotornkul S, Narkpinit S, Harnyuttanakorn P, Singhasivanon P, Maruyama I, Tancharoen S. . Green tea extract supplement inhibition of HMGB1 release in rats exposed to cigarette smoke. . Southeast Asian J Trop Med Public Health41 ( 1 ) 250 - 258 2010.1Reviewed
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Kikuchi K, Tancharoen S, Matsuda F, Biswas KK, Ito T, Morimoto Y, Oyama Y, Takenouchi K, Miura N, Arimura N, Nawa Y, Meng X, Shrestha B, Arimura S, Iwata M, Mera K, Sameshima H, Ohno Y, Maenosono R, Tajima Y, Uchikado H, Kuramoto T, Nakayama K, Shigemori M, Yoshida Y, Hashiguchi T, Maruyama I, Kawahara K. . Edaravone attenuates cerebral ischemic injury by suppressing aquaporin-4. . Biochem Biophys Res Commun.390 ( 4 ) 1121 - 1125 2009.1Reviewed
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Kikuchi K, Kawahara K, Biswas KK, Ito T, Tancharoen S, Morimoto Y, Matsuda F, Oyama Y, Takenouchi K, Miura N, Arimura N, Nawa Y, Meng X, Shrestha B, Arimura S, Iwata M, Mera K, Sameshima H, Ohno Y, Maenosono R, Yoshida Y, Tajima Y, Uchikado H, Kuramoto T, Nakayama K, Shigemori M, Hashiguchi T, Maruyama I. . Minocycline attenuates both OGD-induced HMGB1 release and HMGB1-induced cell death in ischemic neuronal injury in PC12 cells. . Biochem Biophys Res Commun.385 ( 2 ) 132 - 136 2009.1Reviewed
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Kawahara K, Hashiguchi T, Masuda K, Saniabadi AR, Kikuchi K, Tancharoen S, Ito T, Miura N, Morimoto Y, Biswas KK, Nawa Y, Meng X, Oyama Y, Takenouchi K, Shrestha B, Sameshima H, Shimizu T, Adachi T, Adachi M, Maruyama I. . Mechanism of HMGB1 release inhibition from RAW264.7 cells by oleanolic acid in Prunus mume Sieb. et Zucc. . nt J Mol Med.23 ( 5 ) 615 - 620 2009.1Reviewed
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Kikuchi K, Kawahara K, Tancharoen S, Matusda F, Morimoto Y, Ito T, Biswas KK, Takenouchi K, Miura N, Oyama Y, Nawa Y, Arimura N, Iwata M, Tajima Y, Kuramoto T, Nakayama K, Shigemori M, Yoshida Y, Hashiguchi T, Maruyama I. . The free radical scavenger edaravone rescues rats from cerebral infarction by attenuating the release of high-mobility group box-1 in neuronal cells. . J Pharmacol Exp Ther. 329 ( 3 ) 865 - 874 2009.1Reviewed
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Kawahara K, Hashiguchi T, Kikuchi K, Tancharoen S, Miura N, Ito T, Oyama Y, Nawa Y, Biswas KK, Meng X, Morimoto Y, Shrestha B, Sameshima H, Maruyama I. . Induction of high mobility group box 1 release from serotonin-stimulated human umbilical vein endothelial cells. . Int J Mol Med. 22 ( 5 ) 639 - 644 2008.1Reviewed
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Kawahara K, Biswas KK, Unoshima M, Ito T, Kikuchi K, Morimoto Y, Iwata M, Tancharoen S, Oyama Y, Takenouchi K, Nawa Y, Arimura N, Jie MX, Shrestha B, Miura N, Shimizu T, Mera K, Arimura S, Taniguchi N, Iwasaka H, Takao S, Hashiguchi T, Maruyama I. . C-reactive protein induces high-mobility group box-1 protein release through activation of p38MAPK in macrophage RAW264.7 cells. . Cardiovasc Pathol.17 ( 3 ) 129 - 138 2008.1Reviewed
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Kawahara K, Tancharoen S, Hashiguchi T, Unoshima M, Ito T, Kikuchi K, Morimoto Y, Shimizu T, Oyama Y, Takenouchi K, Arimura S, Taniguchi N, Iwata M, Iwasaka H, Maruyama I. . Inhibition of HMGB1 by deep ocean water attenuates endotoxin-induced sepsis. . Med Hypotheses.68 ( 6 ) 1429 - 1430 2007.1Reviewed
Books
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ELISA、マルチプレックス
大山陽子、橋口照人（ Role： Joint author）
呼吸 2013.10
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高フィブリノゲン血症
大山陽子、橋口照人（ Role： Joint author）
別冊日本臨牀 血液症候群(第2版) 2013.5
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HMGB1とRAGEシグナル 生体侵襲と臓器管理 －急性期病態の理解とその対応－
大山陽子、丸山征郎（ Role： Joint author）
救急・集中治療 総合医学社 2008.1
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色調異常：血液、症状からみた血管疾患事典 血管疾患の鑑別診断
大山陽子、丸山征郎（ Role： Joint author）
Vascular Laboratory・メディカ出版 2006.1
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緊急検査と評価
大山陽子、橋口照人、丸山征郎（ Role： Joint author）
診断と治療 増刊号:救急医療 2003.1
Presentations
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大山陽子 漢方薬は自然炎症制御薬となりうるか？～DAMPsコントローラーとしての漢方～
第65回日本東洋医学会学術集会 シンポジウム「東洋医学の発想と近代医学の最前線：未病と自然炎症」 第65回日本東洋医学会学術集会 シンポジウム「東洋医学の発想と近代医学の最前線：未病と自然炎症」
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大山陽子 漢方薬は自然炎症制御薬となりうるか？～自然炎症腎炎モデルを用いた検証～
第64回日本東洋医学会学術集会 シンポジウム「免疫と漢方－関節リウマチを題材に融合治療を考える」 第64回日本東洋医学会学術集会 シンポジウム「免疫と漢方－関節リウマチを題材に融合治療を考える」
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Yoko Oyama, Teruto Hashiguchi, Noboru Taniguchi, Salunya Tancharoen, Yuko Nawa, Tomonori Uchimura, Kamal K. Biswas, Ko-ichi Kawahara, Takao Nitanda, Yoshihisa Umekita, Martin Lotz, Ikuro Maruyama High-mobility group box-1 protein promotes Granulomatous nephritis in a cycle involving monocyte chemoattractant protein - 1 International conference
ESF- JSPS Frontier Science Conference for Young Researchers ESF- JSPS Frontier Science Conference for Young Researchers
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Y. Oyama, T. Hashiguchi, N. Taniguchi, S. Tancharoen, T. Uchimura, K. Biswas, K. Kawahara, T. Nitanda, Y. Umekita, M. Lotz, I. Maruyama. High-mobility Group Box-1 Protein Promotes Granulomatous Nephritis in Adenine-induced nephropathy. International conference
The 18th International Symposium on Molecular Cell Biology of Macrophages 2010. The 18th International Symposium on Molecular Cell Biology of Macrophages 2010.
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Y. Oyama, S. Tancharoen, T. Ito, T. Hashiguchi, T. Uchimura, K. Kawahara, I. Maruyama Chinese herbal medicine "Wu Ling San" had anti-inflammatory activity in crystal induced nephritis in rats. International conference
WorldPharma 2010. WorldPharma 2010.
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Y. Oyama, T. Hashiguchi, N. Taniguchi, S. Tancharoen, Y. Nawa, T. Uchimura, K. Biswas, K. Kawahara, T. Nitanda,Y. Umekita, M. Lotz, I. Maruyama High-mobility group box-1 protein promotes Granulomatous nephritis in adenine-induced nephropathy. International conference
The 4th International HMGB1Symposium SIGNALS OF TISSUE DAMAGE. The 4th International HMGB1Symposium SIGNALS OF TISSUE DAMAGE.
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Y. Oyama, T. Hashiguchi, T. Uchimura, S. Tancharoen, K. Biswas, K. Kawahara, Y. Nawa, T. Nitanda, S. Yamada, Y. Umekita, I. Maruyama High-mobility Group Box-1 Protein Causes Granulomatous Nephritis Formation via a Vicious Cycle with Monocyte Chemoattractant Protein-1 and Tumor Necrosis Factor-a in an Experimental Model. International conference
The Third International Damage Associated Molecular Pattern Molecules (DAMPs) and Alarmins Symposium, The Third International Damage Associated Molecular Pattern Molecules (DAMPs) and Alarmins Symposium,
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Y. Oyama, S. Tancharoen, T. Ito, T. Hashiguchi, T. Uchimura, K. Kawahara, I. Maruyama An Anti-oxidant Capacity of Chinese Herbal Medicine “Wu Ling San” in Experimental Granulomatous Nephritis Model. International conference
The Ⅸth World Conference on Clinical Pharmacology and Therapeutics The Ⅸth World Conference on Clinical Pharmacology and Therapeutics
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Y. Oyama, T. Uchimura, K. Biswas, K. Kawahara, T. Hashiguchi, S. Yamada, I. Maruyama HMGB1 and MCP-1 cooperatively act as smoldering inflammatory mediators forming vicious cycle. An insight from adenine-induced chronic interstitial nephritis model in rats. International conference
EMBO Workshop on Innate Danger Signals and HMGB1 EMBO Workshop on Innate Danger Signals and HMGB1