マリンバイオテクノロジー学会

2015.10

日本がん分子標的治療学会

2015.10

日本衛生学会

2015.10

Hyodo T., Honda A., Yamate S., Kubo Y., Komatsu M., Shiozaki K. .  Elucidation of the mechanism of nuclear localization of Mexican tetra Neu4 via bipartite nuclear localization signal and less conserved regions .  Biochimie212   123 - 134   2023.9Reviewed

Sahashi D., Kubo Y., Ishii M., Ikeda A., Yamasaki C., Komatsu M., Shiozaki K. .  Neu1 deficiency increases the susceptibility of zebrafish to Edwardsiella piscicida infection via lysosomal dysfunction .  Gene836   146667   2022.8Reviewed

Ikeda A., Yamasaki C., Kubo Y., Doi Y., Komamizu M., Komatsu M., Shiozaki K. .  Alteration of the neuronal and glial cell profiles in Neu1-deficient zebrafish .  Glycoconjugate Journal39 ( 4 ) 499 - 512   2022.8Reviewed

Vo L.K., Tran N.T., Kubo Y., Sahashi D., Komatsu M., Shiozaki K. .  Enhancement of Edwardsiella piscicida infection, biofilm formation, and motility caused by N-acetylneuraminate lyase .  Glycoconjugate Journal39 ( 3 ) 429 - 442   2022.6Reviewed

Tran N.T., Vo L.K., Komatsu M., Shiozaki K. .  Involvement of N-acetylneuraminate cytidylyltransferase in Edwardsiella piscicida pathogenicity .  Fish and Shellfish Immunology124   534 - 542   2022.5Reviewed

河辺 ももこ, 堀田 千穂子, 西田 拓未, 久保 友理奈, 小松 正治, 塩﨑 一弘 .  疾患モデルゼブラフィッシュを用いた糖転移ヘスペリジンの抗不安活性解析 .  応用糖質科学：日本応用糖質科学会誌12 ( 1 ) 43 - 44   2022.2

Ikeda A., Komamizu M., Hayashi A., Yamasaki C., Okada K., Kawabe M., Komatsu M., Shiozaki K. .  Neu1 deficiency induces abnormal emotional behavior in zebrafish .  Scientific Reports11 ( 1 ) 13477   2021.12

Oishi K., Morise M., Vo L.K., Tran N.T., Sahashi D., Ueda-Wakamatsu R., Nishimura W., Komatsu M., Shiozaki K. .  Host lactosylceramide enhances Edwardsiella tarda infection .  Cellular Microbiology23 ( 9 ) e13365   2021.9

Kawabe M., Hayashi A., Komatsu M., Inui A., Shiozaki K. .  Ninjinyoeito improves anxiety behavior in neuropeptide Y deficient zebrafish .  Neuropeptides87   102136   2021.6

Honda A., Hayasaka O., Mio K., Fujimura K., Kotani T., Komatsu M., Shiozaki K. .  The involvement of Nile tilapia (Oreochromis niloticus) Neu4 sialidase in neural differentiation during early ontogenesis .  Biochimie185   105 - 116   2021.6

Ryuzono, S., Takase, R., Oishi, K., Ikeda, A., Chigwechokha, P., Funahashi, A., Komatsu, M., Miyagi, T., Shiozaki, K., .  Lysosomal localization of Japanese medaka (Oryzias latipes) Neu1 sialidase and its highly conserved enzymatic profiles with human. .  Gene575   513 - 523   2016Lysosomal localization of Japanese medaka (Oryzias latipes) Neu1 sialidase and its highly conserved enzymatic profiles with human. Reviewed

Aki Funahashi, Masaharu Komatsu, Tatsuhiko Furukawa, Yuki Yoshizono, Hikari Yoshizono, Yasuhiro Orikawa, Shota Takumi, Kazuhiro Shiozaki, Seiichi Hayashi, Yoshio Kaminishi, Takao Itakura. .  Eel green fluorescent protein is associated with resistance to oxidative stress. .  Comparative Biochemistry and Physiology-part C181-182   35 - 39   2016Eel green fluorescent protein is associated with resistance to oxidative stress.Reviewed

Kazuhiro Shiozaki, Yusuke Harasaki, Midori Fukuda, Ayana Yoshinaga, Sena Ryuzono, Petros Kingstone Chigwechokha, Masaharu Komatsu and Taeko Miyagi. .  Positive regulation of myoblast differentiation by medaka Neu3b sialidase through ganglioside desialylation. .  Biochimie123   65 - 72   2016Positive regulation of myoblast differentiation by medaka Neu3b sialidase through ganglioside desialylation. Reviewed

F Moinuddin , Yoshinari Shinsato , Masaharu Komatsu , Ryoichi Mitsuo , Kentaro Minami , Masatatsu Yamamoto , Kohichi Kawahara , Hirofumi Hirano , Kazunori Arita, Tatsuhiko Furukawa .  ATP7B expression confers multidrug resistance through drug sequestration. .  Oncotarget   2016ATP7B expression confers multidrug resistance through drug sequestration.Reviewed

Ayana Yoshinaga, Natsuki Kajiya, Kazuki Oishi, Yuko Kamada, Asami Ikeda, Petros Kingstone Chigwechokha, Toshiro Kibe, Michiko Kishida, Shosei Kishida, Masaharu Komatsu, Kazuhiro Shiozaki .  NEU3 inhibitory effect of naringin suppresses cancer cell growth by attenuation of EGFR signaling through GM3 ganglioside accumulation. .  European Journal of Pharmacology   2016NEU3 inhibitory effect of naringin suppresses cancer cell growth by attenuation of EGFR signaling through GM3 ganglioside accumulation. Reviewed

Aki Funahashi, Takao Itakura, Abeer A.I. Hassanin, Masaharu Komatsu, Seiichi Hayashi, Yoshio kaminishi .  Ubiquitous distribution of fluorescent protein in muscles of four species　and two subspecies of eel (genus Anguilla). .  Journal of Genetics   2016Ubiquitous distribution of fluorescent protein in muscles of four species　and two subspecies of eel (genus Anguilla).Reviewed

Chigwechokha, P., Tabata, M., Shinyoshi, S., Oishi, K., Araki, K., Komatsu, M., Itakura, T., Shiozaki, K., .  Recombinant sialidase NanA (rNanA) cleaves alpha 2-3-linked sialic acid of host cell surface N-linked glycoprotein to promote Edwardsiella tarda infection. .  Fish Shellfish and Immunology47   34 - 45   2015Recombinant sialidase NanA (rNanA) cleaves alpha 2-3-linked sialic acid of host cell surface N-linked glycoprotein to promote Edwardsiella tarda infection.Reviewed

Shota Takumi, Satoshi Ikema,Tamami Hanyu, Yusuke Shima,Takashi Kurimoto, Kazuhiro Shiozaki, Yasumasa Sugiyama, Ho-Dong Park, Seiichi Ando, Tatsuhiko Furukawa, and Masaharu Komatsu .  Naringin attenuates the cytotoxicty of hepatotoxin microcystin-LR by the curious mechanisms to OATP1B1- and OATP1B3-expressing cells. .  Environmental Toxicology and Pharmacology39   974 - 981   2015Naringin attenuates the cytotoxicty of hepatotoxin microcystin-LR by the curious mechanisms to OATP1B1- and OATP1B3-expressing cells. Reviewed

Asami Ikeda, Hayato Ichino, Kiguchiya, S., Chigwechokha, P., Masaharu Komatsu, Kazuhiro Shiozaki. .  Evaluation and identification of potent angiotensin-I converting enzyme inhibitory peptide derived from dwarf gulper shark (Centrophorus atromarginatus). .  Journal of Food Processing and Preservation39   107 - 115   2015Evaluation and identification of potent angiotensin-I converting enzyme inhibitory peptide derived from dwarf gulper shark (Centrophorus atromarginatus). Reviewed

Satoshi Ikema, Shota Takumi, Yuta maeda, Takashi Kurimoto, Shinya Bohda, Petros Kingstone Chigwechokha, Yasumasa Sugiyama, Kazuhiro Shiozaki, Tatsuhiko Furukawa, and Masaharu Komatsu .  Okadaic acid is taken-up into the cells mediated by human hepatocytes transporter OATP1B3. .  Food and Chemical Toxicology83   229 - 236   2015Okadaic acid is taken-up into the cells mediated by human hepatocytes transporter OATP1B3.Reviewed

Hiroyuki Takano, Shota Takumi, Satoshi Ikema, Nozomi Mizoue, Yuki Hotta, Kazuhiro Shiozaki, Yasumasa Sugiyama, Tatsuhiko Furukawa, and Masaharu Komatsu .  Microcystin-LR Induces Anoikis Resistance to the Hepatocyte Uptake Transporter OATP1B3-expressing Cell Lines. .  Toxicology326   53 - 61   2014Microcystin-LR Induces Anoikis Resistance to the Hepatocyte Uptake Transporter OATP1B3-expressing Cell Lines.Reviewed

Shiozaki, K., Ryuzono, S., Matushita, N., Ikeda, A., Takeshita, K., Chigwechokha, P., Komatsu, M., Miyagi, T., .  Molecular cloning and biochemical characterization of medaka (Oryzias latipes) lysosomal neu4 sialidase. .  Fish Physiology and Biochemistry40   1461 - 1472   2014Molecular cloning and biochemical characterization of medaka (Oryzias latipes) lysosomal neu4 sialidase. Reviewed

Liqiang Xie, Tamami Hanyu, Noriko Futatsugi, Masaharu Komatsu, Alan D. Steinman, Ho-Dong Park. .  Inhibitory effect of naringin on microcystin-LR uptake in the freshwater snail Sinotaia histrica. .  Environmental Toxicology and Pharmacology38   430 - 437   2014Inhibitory effect of naringin on microcystin-LR uptake in the freshwater snail Sinotaia histrica. Reviewed

Petros Kingstone Chigwechokha, Masaharu Komatsu, Takao Itakura, Kazuhiro Shiozaki. .  Nile Tilapia Neu3 sialidases: molecular cloning, functional characterization and expression in Oreochromis niloticus. .  Gene552   155 - 164   2014Nile Tilapia Neu3 sialidases: molecular cloning, functional characterization and expression in Oreochromis niloticus. Reviewed

Masaharu Komatsu, Naoki Ichiyama, Takashi Kurimoto, Shota Takumi, Kazuhiro Shiozaki, Yasumasa Sugiyama, Tatsuhiko Furukawa, Seiichi Ando, Saki Itonori, and Hiroaki Saito .  Ceramide Aminoethylphosphonate from Jumbo flying squid Dosidicus gigas attenuates the toxicity of cyanotoxin microcystin-LR .  Fisheries Science79   313 - 320   2013.3Ceramide Aminoethylphosphonate from Jumbo flying squid Dosidicus gigas attenuates the toxicity of cyanotoxin microcystin-LR Reviewed

Kazuhiro Shiozaki, Kazuki Takeshtia, Mako Ikeda, Asami Ikeda, YusukeHarasaki, Masaharu Komatsu, Shoji Yamada, Kazunori Yamaguchi and TaekoMiyagi. .  Molecular cloning and biochemical characterization of two novel Neu3sialidases, neu3a and neu3b, from medaka (Oryzias latipes) .  Biochimie95   280 - 289   2013.1Molecular cloning and biochemical characterization of two novel Neu3sialidases, neu3a and neu3b, from medaka (Oryzias latipes)Reviewed

Yang Li, Wei Hongyi, Masaharu Komatsu, Kenichi Ishibashi, Tatsuo Ito, Takeshi Yoshikawa, and Hiroto Maeda .  Isolation and characterization of bacterial isolates algicidal against a harmful bloom-forming cyanobacterium Microsystis aeruginosa. .  Biocontrol Science17   107 - 114   2012.1Isolation and characterization of bacterial isolates algicidal against a harmful bloom-forming cyanobacterium Microsystis aeruginosa.Reviewed

Malay Choudhury, Takahiro Oku, Shoji Yamada, Masaharu Komatsu, Keita Kudoh, Takao Itakura, Seiichi Ando .  Isolation and characterization of some novel genes of apolipoprotein A-I family in Japanese eel, Anguilla japonica. .  Central European Journal of Biology6   545 - 557   2011.9Isolation and characterization of some novel genes of apolipoprotein A-I family in Japanese eel, Anguilla japonica.Reviewed

Emiko Miyahara, Makiko Nishie, Shota Takumi, Hiroaki Miyanohara, Jun-ichiro Nishi, Kiyotaka Yoshiie, Hiroshi Oda, Minoru Takeuchi, Masaharu Komatsu, Kohji Aoyama, Masahisa Horiuchi, Toru Takeuchi .  Environmental mutagens may be implicated in emergence 1 of drug-resistant microbesa .  FEMS Microbiology Letters317   109 - 116   2011.2Environmental mutagens may be implicated in emergence 1 of drug-resistant microbesaReviewed

Toyohiro Kato, Hiroaki Kawaguchi, Noriaki Miyoshi, Kohji Aoyama, Masaharu Komatsu, Masahisa Horiuchi, Hiroki Yoshida, Toru Takeuchi .  Effect of habitual exercise on renal carcinogenesis by ferric nitrilotriacetate .  Environmental Health and Preventive Medicine 16   232 - 238   2011.1Effect of habitual exercise on renal carcinogenesis by ferric nitrilotriacetate Reviewed

Shota Takumi, Masaharu Komatsu, Tatsuhiko Furukawa, Ryuji Ikeda, Tomoyuki Sumizawa, Hitomi Akenaga, Yuta Maeda, Kohji Aoyama, Koji Arizono, Seiichi Ando,and Toru Takeuchi. .  p53 plays an important role in cell fate determination after exposure to microcystin-LR. .  Environmental Health Perspectives 118   1292 - 1298   2010.11p53 plays an important role in cell fate determination after exposure to microcystin-LR.Reviewed

Miyabi Hirashima, Kazuomi Tsuda, Toshiyuki Hamada, Hiroaki Okamura, Tatsuhiko Furukawa, Shin-ichi Akiyama, Yusuke Tajitsu, Ryuji Ikeda, Masaharu Komatsu, Matsumi Doe, Yoshiki Morimoto, Motoo Shiro, Rob W.M. van Soest, Kaoru Takemura and Tetsuo Iwagawa. .  Cytotoxic Isomalabaricane Derivatives and a Monocytclic Triterpene Glycoside from the Sponge Rhabdastrella globostellata. .  Journal of Natural Products 73   1512 - 1518   2010.9Cytotoxic Isomalabaricane Derivatives and a Monocytclic Triterpene Glycoside from the Sponge Rhabdastrella globostellata.Reviewed

Kimiko Izumo, Masahisa Horiuchi, Masaharu Komatsu, Kohji Aoyama, Bandow K, Tetsuya Matsuguchi, Minoru Takeuchi, Toru Takeuchi. .  Dehydroepiandrosterone increased oxidative stress in a human cell line during differentiation. .  Free Radical Research 43   922 - 931   2009.11Dehydroepiandrosterone increased oxidative stress in a human cell line during differentiation.Reviewed

Malay Choudhury, Shoji Yamada, Masaharu Komatsu, Hideki Kishimura, and Seiichi Ando .  Homologue of mammalian apolipoprotein A-II in nonmammalian vertebrates .  Acta Biochimica et Biophysica Sinica41   370 - 378   2009.10Homologue of mammalian apolipoprotein A-II in nonmammalian vertebratesReviewed

Takahiro Oku, Akira Sugawara, Malay Choudhury, Masaharu Komatsu, Shoji Yamada, and Seiichi Ando .  Lipid and fatty acid compositions differentiate between wild and cultured Japanese eel (Anguilla japonica) .  Food Chemistry 115   436 - 440   2009.4Lipid and fatty acid compositions differentiate between wild and cultured Japanese eel (Anguilla japonica)Reviewed

Shota Takumi, Masaharu Komatsu, Kohji Aoyama, Kunimoto Watanabe, and Toru Takeuchi .  Oxygen induces mutation in a strict anaerobe, Prevotella melaninogenica. .  Free Radical Biology and Medicine.44   1857 - 1862   2008.5Oxygen induces mutation in a strict anaerobe, Prevotella melaninogenica.Reviewed

Ryuji Ikeda, Yusuke Tajitsu, Ken-ichi Iwashita, Xiao-Fang Che, Kenichi Yoshida, Mina Ushiyama, Tatsuhiko Furukawa, Masaharu Komatsu, Tatsuya Yamaguchi, Yoshihiko Shibayama, Masatatsu Yamamoto, Hong-Ye Zhao, Junko Arima, Yasuo Takeda, Shin-ichi Akiyama, and Katsushi Yamada .  Thymidine Phosphorylase Inhibits the Expression of Proapoptic Protein BNIP3 .  Biochemical and Biophysical Research Communications 370   220 - 224   2008.1Thymidine Phosphorylase Inhibits the Expression of Proapoptic Protein BNIP3 Reviewed

Q. Nong, M. Komatsu, K. Izumo, H.P. Indo, B. Xu, K. Aoyama, H.J. Majima, M. Horiuchi, K. Morimoto, T. Takeuchi .  Involvement of reactive oxygen species in microcystin-LR induced cytogenotoxicity .  Free Radical Research41   1326 - 1337   2007.12Involvement of reactive oxygen species in microcystin-LR induced cytogenotoxicityReviewed

Masaharu Komatsu, Tatsuhiko Furukawa, Ryuji Ikeda, Shota Takumi, Nong Qingqing, Kohji Aoyama, Shin-ichi Akiyama, Dietrich Keppler, and Toru Takeuchi .  Involvement of mitogen-activated protein kinase signaling pathways in microcystin-LR-induced apoptosis after its selective uptake mediated by OATP1B1 and OATP1B3 .  Toxicological Sciences97   407 - 416   2007.6Involvement of mitogen-activated protein kinase signaling pathways in microcystin-LR-induced apoptosis after its selective uptake mediated by OATP1B1 and OATP1B3Reviewed

Satsuki Owatari, Satoshi Akune, Masaharu Komatsu, Ryuji Ikeda, Stephan D. Firth, Xiao-Fang Che, Masatatsu Yamamoto, Kazutake Tsujikawa, Masaki Kitazono, Takashi Ishizawa, Toru Takeuchi, Takashi Aikou, Julian F.B. Mercer, Shin-ichi Akiyama, and Tatsuhiko F .  Copper-transporting P-type ATPase, ATP7A, confers multidrug resistance and its expression is related to resistance to SN-38 in clinical colon cancer. .  Cancer Research67   4860 - 4868   2007.5Copper-transporting P-type ATPase, ATP7A, confers multidrug resistance and its expression is related to resistance to SN-38 in clinical colon cancer.Reviewed

Koji Nakatani, Masaharu Komatsu, Toyohiro Kato, Takao Yamanaka, Hiroaki Takekura, Akira Wagatsuma, Kohji Aoyama, Baohui Xu, Takeshi Hirano, Hiroshi Kasai, Seiichi Ando, Toru Takeuchi .  Habitual exercise induced resistance to oxidative stress. .  Free Radical Research39   905 - 911   2005.9Habitual exercise induced resistance to oxidative stress.Reviewed

Katrin Letschert, Masaharu Komatsu, Johanna Hummel-Eisenbeiβ, and Dietrich Keppler .  Vectorial Transport of the Peptide CCK-8 by Double-Transfected MDCKII Cells Stably Expressing the Organic Anion Transporter OATP1B3 (OATP8) and the Export Pump ABCC2 .  Journal of Pharmacology and Experimental Therapeutics313   549 - 556   2005.5Vectorial Transport of the Peptide CCK-8 by Double-Transfected MDCKII Cells Stably Expressing the Organic Anion Transporter OATP1B3 (OATP8) and the Export Pump ABCC2Reviewed

Minyi Shi, Baohui Xu, Kazuko Azakami, Tomohiro Morikawa, Kunitomo Watanabe, Kanehisa Morimoto, Masaharu Komatsu, Kohji Aoyama, and Toru Takeuchi .  Dual role of vitamin C in an oxygen-sensitive system: discrepancy between DNA damage and cell death .  Free Radical Research39   213 - 220   2005.2Dual role of vitamin C in an oxygen-sensitive system: discrepancy between DNA damage and cell deathReviewed

Minyi Shi, Haruko Takeshita, Masaharu Komatsu, Baohui Xu, Kohji Aoyama, and Toru Takeuchi .  Generation of 8-hydroxydeoxyguanosine from DNA with rat liver homogenates .  Cancer Science96   13 - 18   2005.1Generation of 8-hydroxydeoxyguanosine from DNA with rat liver homogenatesReviewed

Masaharu Komatsu, Seiichi Ando, Shota Takumi, Tatsuhiko Furukawa, Yumiko Komatsu, Kohji Aoyama, and Toru Takeuchi .  Development of a simple screening system for phytoecdysteroids in the environmental pollutants using mammalian cell line. .  Current Topics in Pharmacology9   81 - 89   2005.1Development of a simple screening system for phytoecdysteroids in the environmental pollutants using mammalian cell line.Reviewed

Ryuji Ikeda, Tatsuhiko Furukawa, Masaki Kitazono, Kenji Ishitsuka, Hiroshi Okumura, Ayako Tani, Tomoyuki Sumizawa, Misako Haraguchi, Masaharu Komatsu, Hiroshi Uchimiya, Xiao-Qin Ren, Toshiro Motoya, Katsushi Yamada, and Shin-ichi Akiyama. .  Molecular basis for the inhibition of hypoxia-induced apoptosis by 2-deoxy-D-ribose. .  Biochemical and Biophysical Research Communications291   806 - 812   2002.4Molecular basis for the inhibition of hypoxia-induced apoptosis by 2-deoxy-D-ribose.Reviewed

Zhe-Sheng Chen, Shunji Aoki, Masaharu Komatsu, Kazumitsu Ueda, Tomoyuki Sumizawa, Tatsuhiko Furukawa, Hiroshi Okumura, Xiao-Qin Ren, Martin G. Belinsky, Kun Lee, Gary D. Kruh, Motomasa Kobayashi, and Shin-ichi Akiyama. .  Reversal of drug resistance mediated by multidrug resistance protein (MRP)1 by dual effects of Agosterol A on MRP1 function. .  International Journal of Cancer 93   107 - 113   2001.7Reversal of drug resistance mediated by multidrug resistance protein (MRP)1 by dual effects of Agosterol A on MRP1 function.Reviewed

安藤 和毅, 池田 樹生, 内匠 正太, 小松 正治   動脈硬化症の予防に有効な食品成分の探索  

日本衛生学雑誌  2024.3  (一社)日本衛生学会

芝 佳奈, 江藤 里紗, 内匠 正太, 小松 正治   柑橘類を用いたアオコ毒Microcystin-LRの細胞毒性抑制効果の検討  

日本衛生学雑誌  2024.3  (一社)日本衛生学会