Updated on 2023/10/23

写真a

 
OOGAI Yuichi
 
Organization
Research Field in Dentistry, Medical and Dental Sciences Area Graduate School of Medical and Dental Sciences Health Research Course Developmental Medicine Lecturer
Title
Lecturer

Degree

  • 博士(歯学) ( 2012.1   鹿児島大学 )

Research History

  • Kagoshima University   Lecturer

    2022.7

  • Kagoshima University

    2008.4

  • Kagoshima University   Assistant Professor

    2008.4

Professional Memberships

  • 歯科基礎医学会

    2015.5

  • 日本細菌学会

    2008.10

 

Papers

  • Tsujii T, Kawada-Matsuo M, Migita H, Ohta K, Oogai Y, Yamasaki Y, Komatsuzawa H. .  Antibacterial activity of phellodendron bark against Streptococcus mutans .  Microbiology and immunology   2020.4Antibacterial activity of phellodendron bark against Streptococcus mutansReviewed

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  • Kawada-Matsuo M, Watanabe A, Arii K, Oogai Y, Noguchi K, Miyawaki S, Hayashi T, Komatsuzawa H .  Staphylococcus Aureus Virulence Affected by an Alternative Nisin A Resistance Mechanism .  Appl Environ Microbiol .   2020.4Staphylococcus Aureus Virulence Affected by an Alternative Nisin A Resistance MechanismReviewed

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  • Yamashita T, Kawada-Matsuo M, Katsumata T, Watanabe A, Oogai Y, Nishitani Y, Miyawaki S, Komatsuzawa H. .  Antibacterial Activity of Disodium Succinoyl Glycyrrhetinate, a Derivative of Glycyrrhetinic Acid Against Streptococcus Mutans .  Microbiol immunol.   2019.1Antibacterial Activity of Disodium Succinoyl Glycyrrhetinate, a Derivative of Glycyrrhetinic Acid Against Streptococcus MutansReviewed

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  • Arii K, Kawada-Matsuo M, Oogai Y, Noguchi K, Komatsuzawa H. .  Single Mutations in BraRS Confer High Resistance Against Nisin A in Staphylococcus Aureus .  Microbiologyopen   2019.1Single Mutations in BraRS Confer High Resistance Against Nisin A in Staphylococcus AureusReviewed

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  • Oogai Y, Gotoh Y, Ogura Y, Kawada-Matsuo M, Hayashi T, Komatsuzawa H. .  Small RNA repertoires and their intraspecies variation in Aggregatibacter actinomycetemcomitans. .  DNA research   2018.4Small RNA repertoires and their intraspecies variation in Aggregatibacter actinomycetemcomitans.Invited Reviewed

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  • Oogai Y, Kawada-Matsuo M, Komatsuzawa H .  Staphylococcus aureus SrrAB Affects Susceptibility to Hydrogen Peroxide and Co-Existence with Streptococcus sanguinis. .  PLoS ONE   2017.7Staphylococcus aureus SrrAB Affects Susceptibility to Hydrogen Peroxide and Co-Existence with Streptococcus sanguinis.Reviewed

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  • Kawada-Matsuo M, Oogai Y, Komatsuzawa H. .  Sugar Allocation to Metabolic Pathways is Tightly Regulated and Affects the Virulence of Streptococcus mutans. .  Genes   2016.12Sugar Allocation to Metabolic Pathways is Tightly Regulated and Affects the Virulence of Streptococcus mutans.Reviewed

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  • Oyama K, Kawada-Matsuo M, Oogai Y, Hayashi T, Nakamura N, Komatsuzawa H. .  Antibacterial Effects of Glycyrrhetinic Acid and Its Derivatives on Staphylococcus aureus. .  PLoS ONE   2016.11Antibacterial Effects of Glycyrrhetinic Acid and Its Derivatives on Staphylococcus aureus.Reviewed

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  • Oogai Y, Yamaguchi M, Kawada-Matsuo M, Sumitomo T, Kawabata S, Komatsuzawa H. .  Lysine and Threonine Biosynthesis from Aspartate Contributes to Staphylococcus aureus Growth in Calf Serum. .  Applied and Environmental Microbiology   2016.9Lysine and Threonine Biosynthesis from Aspartate Contributes to Staphylococcus aureus Growth in Calf Serum.Reviewed

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  • Kawada-Matsuo M, Tatsuno I, Arii K, Zendo T, Oogai Y, Noguchi K, Hasegawa T, Sonomoto K, Komatsuzawa H. .  Two-Component Systems Involved in Susceptibility to Nisin A in Streptococcus pyogenes. .  Applied and Environmental Microbiology   2016.9Two-Component Systems Involved in Susceptibility to Nisin A in Streptococcus pyogenes.Reviewed

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  • Kawada-Matsuo M, Shammi F, Oogai Y, Nakamura N, Sugai M, Komatsuzawa H. .  C55 bacteriocin produced by ETB-plasmid positive Staphylococcus aureus strains is a key factor for competition with S. aureus strains. .  Microbiol Immunol.   2016.3C55 bacteriocin produced by ETB-plasmid positive Staphylococcus aureus strains is a key factor for competition with S. aureus strains.Reviewed

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  • Shimotahira N, Oogai Y, Kawada-Matsuo M, Yamada S, Fukutsuji K, Nagano K, Yoshimura F, Noguchi K, Komatsuzawa H. .  The Surface Layer of Tannerella forsythia Contributes to Serum Resistance and Oral Bacterial Coaggregation. .  Infection and immunity81 ( 4 ) 1198 - 1206   2013.4The Surface Layer of Tannerella forsythia Contributes to Serum Resistance and Oral Bacterial Coaggregation.Reviewed

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  • Fujishima K, Kawada-Matsuo M, Oogai Y, Tokuda M, Torii M, Komatsuzawa H. .  dpr and sod in Streptococcus mutans are involved in coexistence with S. sanguinis, and PerR is associated with resistance to H2O2. .  Appl Environ Microbiol795 ( 5 ) 1436 - 1443   2013.3dpr and sod in Streptococcus mutans are involved in coexistence with S. sanguinis, and PerR is associated with resistance to H2O2.Reviewed

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  • Kukita K, Kawada-Matsuo M, Oho T, Nagatomo M, Oogai Y, Hashimoto M, Suda Y, Tanaka T, Komatsuzawa H. .  Staphylococcus aureus SasA is responsible for binding to salivary agglutinin, gp340, derived from human saliva. .  Infection and Immunity   2013.2Staphylococcus aureus SasA is responsible for binding to salivary agglutinin, gp340, derived from human saliva.Reviewed

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  • Kawada-Matsuo M, Yoshida Y, Zendo T, Nagao J, Oogai Y, Nakamura Y, Sonomoto K, Nakamura N, Komatsuzawa H. .  Three distinct two-component systems are involved in resistance to the class I bacteriocins, Nukacin ISK-1 and nisin A, in Staphylococcus aureus. .  PLoS One8 ( 4 ) e69455   2013.1Three distinct two-component systems are involved in resistance to the class I bacteriocins, Nukacin ISK-1 and nisin A, in Staphylococcus aureus.Reviewed

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  • Kawada-Matsuo M, Oogai Y, Zendo T, Nagao J, Shibata Y, Yamashita Y, Ogura Y, Hayashi T, Sonomoto K, Komatsuzawa H. .  Involvement of the novel two-component NsrRS and LcrRS systems in distinct resistance pathways against nisin A and nukacin ISK-1 in Streptococcus mutans. .  Applied and Environmental Microbiology79 ( 15 ) 4751 - 4755   2013.1Involvement of the novel two-component NsrRS and LcrRS systems in distinct resistance pathways against nisin A and nukacin ISK-1 in Streptococcus mutans.Reviewed

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  • Mazda Y, Kawada-Matsuo M, Kanbara K, Oogai Y, Shibata Y, Yamashita Y, Miyawaki S, Komatsuzawa H. .  Association of CiaRH with resistance of Streptococcus mutans to antimicrobial peptides in biofilms. .  Mol Oral Microbiol. 27 ( 2 ) 124 - 135   2012.4Association of CiaRH with resistance of Streptococcus mutans to antimicrobial peptides in biofilms.Reviewed

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  • Kawada-Matsuo M, Mazda Y, Oogai Y, Kajiya M, Kawai T, Yamada S, Miyawaki S, Oho T, Komatsuzawa H. .  GlmS and NagB Regulate Amino Sugar Metabolism in Opposing Directions and Affect Streptococcus mutans Virulence. .  PLoS One   2012.3GlmS and NagB Regulate Amino Sugar Metabolism in Opposing Directions and Affect Streptococcus mutans Virulence.Reviewed

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  • Tateishi F, Hasegawa-Nakamura K, Nakamura T, Oogai Y, Komatsuzawa H, Kawamata K, Douchi T, Hatae M, Noguchi K. .  Detection of Fusobacterium nucleatum in chorionic tissues of high-risk pregnant women .  J Clin Periodontol.   2012.1Detection of Fusobacterium nucleatum in chorionic tissues of high-risk pregnant womenReviewed

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  • Yuichi Oogai, Miki Matsuo, Masahito Hashimoto, Fuminori Kato, Motoyuki Sugai, Hitoshi Komatsuzawa. .  Expressions of virulence factors in Staphylococcus aureus grown in serum. .  Applied and Environmental Microbiology   2011.9Expressions of virulence factors in Staphylococcus aureus grown in serum.Reviewed

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  • Yuma Yoshida, Miki Matsuo, Yuichi Oogai, Fuminori Kato, Norifumi Nakamura, .  Bacitracin sensing and resistance in Staphylococcus aureus. .  FEMS Microbiology Letters320 ( 1 ) 33 - 39   2011.7Bacitracin sensing and resistance in Staphylococcus aureus.Reviewed

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  • Miki Matsuo, Yuichi Oogai, Fuminori Kato, Motoyuki Sugai, Hitoshi Komatsuzawa. .  Growth-phase dependence of susceptibility to antimicrobial peptides in Staphylococcus aureus. .  Microbiology157 ( Pt6 ) 1786 - 1797   2011.6Growth-phase dependence of susceptibility to antimicrobial peptides in Staphylococcus aureus.Reviewed

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  • Miki Matsuo, Fuminori Kato, Yuichi Oogai, Toshihisa Kawai, Motoyuki Sugai, Hitoshi Komatsuzawa. .  Distinct two-component systems in methicillin-resistant Staphylococcus aureus can change the susceptibility to antimicrobial agents. .  Journal of Antimicrobial Chemotherapy65 ( 7 ) 1536 - 1537   2010.7Distinct two-component systems in methicillin-resistant Staphylococcus aureus can change the susceptibility to antimicrobial agents.Reviewed

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  • Yasunori Sasakura, Yuichi Oogai, Terumi Matsuoka, Noriyuki satoh, Satoko Awazu .  Transposon mediated transgenesis in a marine invertebrate chordate: Ciona intestinalis. .  Genome Biologyvolume 8 ( suppl. 8 ) S3   2007.10Transposon mediated transgenesis in a marine invertebrate chordate: Ciona intestinalis.Reviewed

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Presentations

  • 大貝悠一 渡邉温子 松尾美樹 小松澤均   Novel bacteriocin produced by Staphylococcus epidermidis active against nasal commensals  

    日本細菌学会総会 

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    Event date: 2020.2

    Language:English   Presentation type:Poster presentation  

  • 大貝悠一、小松澤均   Distribution and expression of insertion sequences in Aggregatibacter actinomycetemcomitans  

    第92回日本細菌学会総会 

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    Event date: 2019.4

    Language:English   Presentation type:Poster presentation  

  • 大貝悠一   Aggregatibacter actinomycetemcomitans における small RNA レパートリーとその種内多様性   Invited

    第91回日本細菌学会総会 

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    Event date: 2018.3

    Language:Japanese   Presentation type:Oral presentation (general)  

  • 大貝悠一、後藤恭宏、小椋義俊、林哲也、小松澤均   Aggregatibacter actinomycetemcomitans におけるsmall RNA の同定及び株間にお ける発現性の解析  

    第70 回 日本細菌学会九州支部総会 

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    Event date: 2017.9

    Language:Japanese   Presentation type:Oral presentation (general)  

  • 大貝悠一、後藤恭宏、小椋義俊、林哲也、小松澤均   Identification and expression analysis of small RNAs in Aggregatibacter actinomycetemcomitans  

    第90回日本細菌学会総会 

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    Event date: 2017.3

    Language:English   Presentation type:Poster presentation  

  • 大貝悠一, 小松澤均   Aggregatibacter actinomycetemcomitansにおけるsmall RNAの同定  

    第58回 歯科基礎医学会学術大会 

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    Event date: 2016.8

    Language:English   Presentation type:Poster presentation  

  • 大貝 悠一、小松澤 均   黄色ブドウ球菌のHmpはStreptococcus sanguinisの産生する過酸化水素感受性に関与する   International conference

    第98回日本細菌学会総会 

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    Event date: 2016.3

    Language:English   Presentation type:Poster presentation  

  • 大貝悠一、 小松澤均   黄色ブドウ球菌の牛血清中における病原性因子発現性及び増殖性  

    第57回歯科基礎医学会学術大会 

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    Event date: 2015.9

    Language:English   Presentation type:Poster presentation  

  • 大貝悠一 小松澤均   黄色ブドウ球菌のSrrABはStreptococcus sanguinisの産生する過酸化水素感受性に影響する  

    日本細菌学会総会  日本細菌学会総会

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    Event date: 2015.3

    Language:Japanese  

    Venue:岐阜  

    国内学会

  • Yuichi Oogai, Hitoshi Komatsuzawa   Threonine biosynthesis is important for Staphylococcus aureus growth in serum  

    日本細菌学会総会  日本細菌学会総会

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    Event date: 2014.3

    Language:Japanese  

    Venue:東京  

    国内学会

  • Yuichi Oogai and Hitoshi Komatsuzawa   Analysis of the Fur family proteins in Staphylococcus aureus  

    第86回日本細菌学会総会 

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    Event date: 2013.3

    Language:English   Presentation type:Oral presentation (general)  

  • 大貝 悠一、小松澤 均   黄色ブドウ球菌Fur様タンパク(Fur, PerR, Zur)の解析  

    第65回日本細菌学会九州支部総会 

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    Event date: 2012.8

    Language:Japanese   Presentation type:Oral presentation (general)  

  • Yuichi Oogai, Fuminori Kato, Motoyuki Sugai, Hitoshi Komatsuzawa.   Transcriptional regulator of virulence factors in Staphylococcus aureus in iron restricted condition  

    日本細菌学会総会  日本細菌学会総会

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    Event date: 2012.3

    Language:Japanese  

    Venue:長崎  

    国内学会

  • 大貝悠一、 小松澤均   黄色ブドウ球菌の血清及び鉄欠乏環境下における病原性因子発現解析  

    第4回細菌学・若手コロッセウム 

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    Event date: 2010.8

    Language:Japanese   Presentation type:Oral presentation (general)  

  • 大貝悠一、橋本雅仁、小松澤均   黄色ブドウ球菌の遊離鉄獲得を阻害する血清中因子の解析  

    第83回日本細菌学会総会  第83回日本細菌学会総会

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    Event date: 2010.3

    Language:Japanese  

    Venue:横浜  

    国内学会

  • 大貝悠一、 小松澤均   黄色ブドウ球菌の血清中における病原性因子発現解析  

    若手研究者育成のためのワークショップ〜若手コロセウム (III) at 宮崎 

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    Event date: 2009.10

    Language:Japanese   Presentation type:Oral presentation (general)  

  • Yuichi Oogai, Fuminori kato, Motoyuki Sugai, Hitoshi Komatsuzawa   Effect of iron on the expression of virulence factors of S. aureus grown in serum  

    第82回日本細菌学会総会  第82回日本細菌学会総会

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    Event date: 2009.3

    Language:Japanese  

    Venue:名古屋国際会議場  

    国内学会

  • Yuichi Oogai, Motoyuki Sugai, Hitoshi Komatsuzawa   Expression of virulence factors of Stapylococcus aureus in serum   International conference

    The 8th International Forum on Infection and Immunity  The 8th International Forum on Infection and Immunity

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    Event date: 2008.9

    Language:English  

    Venue:兵庫  

    国際学会

  • 大貝悠一、小松澤均、菅井基行   血清中における黄色ブドウ球菌の病原性因子発現解析  

    第81回日本細菌学会総会  第81回日本細菌学会総会

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    Event date: 2008.3

    Language:Japanese  

    Venue:京都  

    国内学会

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Research Projects

  • 歯周病原因菌の病原性因子及び挿入配列を制御するsmall RNAの解析

    2020.4 - 2022.3

    科学研究費補助金  基盤研究(C)

  • A.actinomycetemcomitansの産生する生理活性ペプチドの探索

    2017.4 - 2020.3

    科学研究費補助金  基盤研究(C)

  • A.actinomycetemcomitans表層タンパクの同定及び病原性解析

    2014.4 - 2017.3

    科学研究費補助金  若手研究(B)

  • 歯周病原因菌表層タンパクの新規病原性因子の同定及び解析

    2010.4 - 2011.3

    科学研究費補助金  若手研究(B)