研究者詳細 - 吉田　昌弘

論文 - 吉田　昌弘

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Jaya Hardi, Tristan Tijsseling, Hayato Takase, Masahiro Yoshida, Koichiro Shiomori and Hideki Matsune . Chitosan-tripolyphosphate-tannic acid cryogels as a biocompatible adsorbent for the removal of Cu2+ ions . Royal Society Open Science12 ( 8 ) Article ID:242274 2025年7月査読

亀澤美晴、田尻隼、日高美好、高木斗志彦、佐々木浩之、高坂明宏、岩森勝茂、大角義浩、武井孝行、吉田昌弘 . 近赤外吸収色素を固定化したナノカプセルの粒子径制御 . 化学工学論文集51 ( 3 ) 43 - 47 2025年3月査読

佐用拓海、丸本颯人、西尾憲悟、後藤啓太、福田一石、清水康智、川崎剛美、大角義浩、高瀬隼、武井孝行、吉田昌弘 . メラミン-ホルムアルデヒド壁在を有する中空マイクロカプセルの製造ならびに特性評価 . 科学・技術研究14 ( 1 ) 1 - 6 2025年2月査読

草野奈央、吉永拓真、清山史朗、吉田昌弘、武井孝行 . ベイズ最適化を利用したコアセルベーションマイクロカプセル調製条件の効率的最適化 . 化学工学論文集51 ( 3 ) 64 - 67 2025年査読

田尻隼、日高美好、高木斗志彦、佐々木浩之、高坂明宏、岩森勝茂、大角義浩、武井孝行、吉田昌弘 . 機能性色素を固定化したナノ粒子の調製技術に関する基礎研究 . 粉体工学会誌62 ( 11 ) 640 - 644 2025年

Hosokawa, Y., Goshima, T., Kai, T., Kobaru, S., Ohzuno, Y., Nii, S., Kiyoyama, S., Yoshida, M., and Takei, T. . Preparation of alginate hydrogel beads on a superhydrophobic surface with calcium salt powder to enhance the mechanical strength and encapsulation efficiency of ingredients . 17 ( 6027 ) 2024年12月査読

Yamashita,Y.,YPhzuno,Y.,Yoshida,M.,and Takei,T. . Autoclaving achieves pH-neutralization,hydrogelation,and sterilization of chitosan hydrogels in one step . Biomedical EngineeringMacromol ( 4 ) 376 - 386 2024年5月査読

伊藤拓人, 松元駿知, 吉塚和治, 吉田昌弘, 武井孝行 . ポリエチレングリコールによるリチウム吸着剤内包カプセルの多孔質化およびリチウム吸着特性への影響調査 . 化学工学論文集50 ( 2 ) 57 - 63 2024年3月査読

記述言語：日本語出版者・発行元：公益社団法人化学工学会

<p>本報では，サイズの小さなリチウム吸着剤を疎水性高分子からなるカプセルに内包することで，ハンドリング性を向上させることを第一の目的とした．さらに，ポリエチレングリコール（PEG）を利用してカプセルを多孔質化し，リチウム吸着特性を向上させることを第二の目的とした．ハンセン溶解度パラメーターをもとにカプセルの壁材として選択したポリメタクリル酸メチル（PMMA）樹脂は強度に優れている．しかし，PMMAは物質透過性に乏しいので，PEGを含ませ，カプセル固化後にPEGを除去することでカプセルを多孔質化した．この細孔により，吸着剤内包カプセルのリチウム吸着性能の低下が抑制できることが示された．</p>

DOI： 10.1252/kakoronbunshu.50.57

Scopus

Shiomori K., Matsune H., Inda N.I., Kiyoyama S., Takei T., Yoshida M. . Extraction properties of Cu(II) from aqueous solution with PVA/Alg cross-linked gel microcapsules immobilizing fine droplets of phenolic oxime extractant . AIP Conference Proceedings2719 2023年5月査読

記述言語：日本語出版者・発行元：AIP Conference Proceedings

Crosslinked-gel microcapsules immobilized small droplets of phenolic oxime extractant, 1-(2-hydroxy-5-nonylphenyl) ethanone oxime (LIX84-I) were prepared from O/W emulsion using falling-drop method followed by crosslinking of sodium alginate (Na-Alg) by Ca2+ ion and crosslinking of polyvinyl alcohol (PVA) by glutaraldehyde. A lot of fine droplets of LIX84-I were successfully immobilized in the microcapsules. The LIX84-I contents in the microcapsules increased with an increase in the LIX84-I amounts to the aqueous phase. The maximum extracted amounts of Cu(II) increased linearly with the LIX84-I contents with a slope of 1/2 which means two molecules of LIX84-I react with one Cu(II) ion. The extraction rate was not significantly affected by the size of the extractant droplets dispersed in the microcapsules. The microcapsules could be used repeatedly for the extraction and back-extraction of Cu(II).

DOI： 10.1063/5.0133362

Scopus

Yamashita Y., Ohzuno Y., Saito Y., Fujiwara Y., Yoshida M., Takei T. . Autoclaving-Triggered Hydrogelation of Chitosan-Gluconic acid Conjugate Aqueous Solution for Wound Healing . Gels9 ( 4 ) 2023年4月査読

記述言語：日本語出版者・発行元：Gels

Moist wound healing is known to heal wounds faster than dry wound healing. Hydrogel wound dressings are suitable for moist wound healing because of their hyperhydrous structure. Chitosan, a natural polymer, promotes wound healing by stimulating inflammatory cells and releasing bioactive compounds. Therefore, chitosan hydrogel has great potential as a wound dressing. In our previous study, physically crosslinked chitosan hydrogels were successfully prepared solely by freeze-thawing of chitosan-gluconic acid conjugate (CG) aqueous solution without using any toxic additives. Furthermore, the CG hydrogels could be sterilized by autoclaving (steam sterilization). In this study, we showed that autoclaving (121 °C, 20 min) of a CG aqueous solution simultaneously achieved gelation of the solution and sterilization of the hydrogel. Hydrogelation of CG aqueous solution by autoclaving is also physically crosslinking without any toxic additives. Further, we showed that the CG hydrogels retained favorable biological properties of the CG hydrogels prepared by freeze-thawing and subsequent autoclaving. These results indicated that CG hydrogels prepared by autoclaving were promising as wound dressings.

DOI： 10.3390/gels9040280

Scopus

PubMed

Takei T., Tomimatsu R., Matsumoto T., Sreejith K.R., Nguyen N.T., Yoshida M. . Hydrophobically Modified Gelatin Particles for Production of Liquid Marbles . Polymers14 ( 22 ) 2022年11月査読

記述言語：日本語出版者・発行元：Polymers

The unique properties and morphology of liquid marbles (LMs) make them potentially useful for various applications. Non-edible hydrophobic organic polymer particles are widely used to prepare LMs. It is necessary to increase the variety of LM particles to extend their use into food and pharmaceuticals. Herein, we focus on hydrophobically modified gelatin (HMG) as a base material for the particles. The surface tension of HMG decreased as the length of alkyl chains incorporated into the gelatin and the degree of substitution (DS) of the alkyl chains increased. HMG with a surface tension of less than 37.5 mN/m (determined using equations based on the Young–Dupré equation and Kaelble–Uy theory) successfully formed LMs of water. The minimum surface tension of a liquid in which it was possible to form LMs using HMG particles was approximately 53 mN/m. We also showed that the liquid-over-solid spreading coefficient (Formula presented.) is a potential new factor for predicting if particles can form LMs. The HMG particles and the new system for predicting LM formation could expand the use of LMs in food and pharmaceuticals.

DOI： 10.3390/polym14224849

Scopus

PubMed

Novel hydrophobically modified agarose cryogels fabricated using dimethyl sulfoxide . Journal of Bioscience and Bioengineering133 ( 4 ) 390 - 395 2022年4月査読

Evans Courtney, Morimitsu Yuto, Nishi Rikako, Yoshida Masahiro, Takei Takayuki . ジメチルスルホキシドを用いて作成された新規疎水性修飾アガロースクリオゲル(Novel hydrophobically modified agarose cryogels fabricated using dimethyl sulfoxide) . Journal of Bioscience and Bioengineering133 ( 4 ) 390 - 395 2022年4月査読

記述言語：英語出版者・発行元：(公社)日本生物工学会

疎水性修飾アガロース(HMA)の作成の新しい方法を報告した。アガロースのヒドロキシル基を活性化することにより、活性化ヒドロキシル基と脂肪アルデヒドのアミンの結合を介して疎水性修飾を作成した。HMAは水に不溶性で、ジメチルスルホキシドを用いてクリオゲルを作成する新しい方法を開発した。HMAクリオゲルの試験によって、HMAクリオゲルは未修飾アガロースクリオゲルよりも疎水性色素を多く吸着でき、HMAクリオゲルからの疎水性色素の遊離を調節できることが示された。以上より、この方法で作成したHMAクリオゲルは薬物送達システム(DDS)として使用できると考えられた。

Evans C, Morimitsu Y, Nishi R, Yoshida M, Takei T . Novel hydrophobically modified agarose cryogels fabricated using dimethyl sulfoxide. . Journal of bioscience and bioengineering133 ( 4 ) 390 - 395 2022年4月査読

Takumi Shibata, Ryohei Ashitani, Masahiro Yoshida, and Takayuki Takei . Novel flow microreactor with blood capillary network-like microchannels . Studies in Science and Technology10 ( 2 ) 147 - 150 2021年12月査読

Courtney Evans, Yuto Morimitsu, Tsubasa Hisadome, Futo Inomoto, Masahiro Yoshida, Takayuki Takei . Optimized hydrophobically modified chitosan cryogels for strength and drug delivery systems . Journal of Bioscience and Bioengineering132 ( 1 ) 81 - 87 2021年7月査読

Evans C., Morimitsu Y., Hisadome T., Inomoto F., Yoshida M., Takei T. . Optimized hydrophobically modified chitosan cryogels for strength and drug delivery systems . Journal of Bioscience and Bioengineering132 ( 1 ) 81 - 87 2021年7月

記述言語：日本語出版者・発行元：Journal of Bioscience and Bioengineering

This research reports the success of the fabrication of hydrophobically modified chitosan cryogel. Chitosan was modified with alkyl groups through reductive animation. By varying the alkyl chain length and the substitution degree, the resulting cryogel could be optimized for strength, and the adsorption and release of hydrophobic dye, a model for hydrophobic medicines. By optimizing these attributes, the hydrogel was found to have the potential as a biomedical material.

DOI： 10.1016/j.jbiosc.2021.03.008

Scopus

PubMed

Kouji HARAMAKI, Yoshihiro OHZUNO, Shiro KIYOYAMA, Koichiro SHIOMORI,Yasuo HATATE, Takayuki TAKEI and Masahiro YOSHIDA . Effect of maintaining activity by addition of sugars for microencapsulated thatch-degrading microorganism . Studies in Science and Technology10 ( 1 ) 37 - 40 2021年6月査読

塩盛弘一郎、松根英樹、清山史朗、武井孝行、吉田昌弘、馬越大 . Recent developments of microcapsules and polymer particles for separation medium . Journal of Physics: Conference Series1763 ( 1 ) 2021年2月

記述言語：日本語出版者・発行元：Journal of Physics: Conference Series

Microcapsules and porous polymer particles containing extractants, which are functional molecules to extract target ions or molecules by specific interaction using in solvent extraction process, are expected to be an effective separation medium of various substances from aqueous solution in hydrometallurgical process of harmful or valuable metals and in environmental protection processes from various pollutants. The preparation method, encapsulating materials and application area of these materials has been developed and extended in recent years. Recent topics of this field was been presented. The research on the polymeric particles for separation medium investigated by authors was introduced and showed the structural effect of the polymeric particles containing extractant on the separation performance of metal ion and chiral separation of amino acids by porous particles impregnated with phospholipids.

DOI： 10.1088/1742-6596/1763/1/012011

Scopus

服巻晃志、大角義浩、清山史朗、塩盛弘一郎、幡手泰雄、吉田昌弘 . カプセル化したサッチ分解菌の糖類添加による活性維持の効果 . 科学と技術研究 2021年査読

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論文 - 吉田　昌弘