論文 - 馬場 昌範
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Hirota Y., Okamoto M., Baba M., Suhara Y. . Potential of fat-soluble vitamins as a platform for antiviral drug development . Bioorganic and Medicinal Chemistry Letters127 130292 - 130292 2025年11月国際誌
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Samunuri R., Toyama M., Kasula M., Jha A.K., Okamoto M., Baba M., Sharon A. . Synthesis, Cytotoxicity, and Mechanistic Evaluation of 7-Deazapurine-Based Neplanocin Analogues as Selective Anti-HBV Agents . Chemistryselect10 ( 22 ) 2025年6月
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Aoki S., Tanaka T., Yokoi K., Kanbe A., Morita T., Nii M., Satoh H., Kakihana M., Otaki S., Sekiguchi S., Nakamura K., Tojo T., Baba M., Okamoto M. . Design, Synthesis, and Anti-SARS-CoV-2 Activity of Amodiaquine Analogs . Chemical and Pharmaceutical Bulletin73 ( 4 ) 355 - 368 2025年4月
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Kasula M., Toyama M., Samunuri R., Jha A.K., Okamoto M., Baba M., Sharon A. . Pyrazolo[3,4-d]pyrimidine-based neplanocin analogues identified as potential de novo pharmacophores for dual-target HBV inhibition . RSC Medicinal Chemistry16 ( 4 ) 1740 - 1745 2025年2月国際誌
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Ishikawa T., Matsumoto K., Hamada T., Koze H., Baba M., Okamoto M., Sudoh M. . In Silico Discovery of SARS-CoV-2 Main Protease Inhibitors Using Docking, Molecular Dynamics, and Fragment Molecular Orbital Calculations . Journal of Physical Chemistry B129 ( 6 ) 1740 - 1749 2025年2月
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Koze H., Sudoh M., Onitsuka S., Okamura H., Ishikawa T., Tani F., Miyata-Yabuki Y., Shirouzu M., Baba M., Okamoto M., Hamada T. . Sulfoquinovosyl diacylglycerol, a component of Holy Basil Ocimum tenuiflorum, inhibits the activity of the SARS-CoV-2 main protease and viral replication in vitro . Journal of Natural Medicines79 ( 1 ) 122 - 133 2025年1月
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Homma T, Okamoto M, Koharazawa R, Hayakawa M, Fushimi T, Tode C, Hirota Y, Osakabe N, Baba M, Suhara Y . Exploring Novel Vitamin K Derivatives with Anti-SARS-CoV-2 Activity. . ACS omega8 ( 45 ) 42248 - 42263 2023年11月査読 国際誌
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小原沢 諒人, 岡本 実佳, 本間 大暉, 早川 真由, 廣田 佳久, 馬場 昌範, 須原 義智 . 抗SARS-CoV-2活性を有するビタミンK誘導体の創製 . ビタミン97 ( 4 ) 228 - 228 2023年4月
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Baba M., Okamoto M., Toyama M., Sakakibara N., Shimojima M., Saijo M., Niwa T., Yagi Y. . Amodiaquine derivatives as inhibitors of severe fever with thrombocytopenia syndrome virus (SFTSV) replication . Antiviral Research210 105479 - 105479 2023年2月国際誌
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Kajiya T, Sawayama H, Arima E, Okamoto M, Baba M, Toyama M, Okuya K, Ozawa M, Atsuchi N, Nishi J, Suda Y . Novel RT-PCR Using Sugar Chain-Immobilized Gold-Nanoparticles Correlates Patients' Symptoms: The Follow-Up Study of COVID-19 Hospitalized Patients. . Viruses14 ( 11 ) 2577 - 2577 2022年11月査読
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Toyama M., Watashi K., Ikeda M., Yamashita A., Okamoto M., Moriishi K., Muramatsu M., Wakita T., Sharon A., Baba M. . Novel Neplanocin A Derivatives as Selective Inhibitors of Hepatitis B Virus with a Unique Mechanism of Action . Antimicrobial Agents and Chemotherapy66 ( 6 ) e0207321 2022年6月
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本間 大暉, 岡本 実佳, 馬場 昌範, 須原 義智 . 抗ウイルス活性を有する新規ビタミン誘導体の研究 . ビタミン96 ( 4 ) 189 - 189 2022年4月
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Ukawa M, Endo R, Yagi H, Tomono T, Miyata K, Shigeno K, Tobita E, Uto T, Baba M, Sakuma S . Mechanism on antigen delivery under mucosal vaccination using cell-penetrating peptides immobilized at multiple points on polymeric platforms. . International journal of pharmaceutics613 121376 - 121376 2022年2月国際誌
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Okamoto M. . Induction of E. coli-derived endonuclease MazF suppresses HIV-1 production and causes apoptosis in latently infected cells . Biochemical and Biophysical Research Communications530 ( 3 ) 597 - 602 2020年9月査読
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Yokota R. . Novel anti-CD70 antibody drug conjugate for the treatment of adult T-cell leukemia (ATL) . Anticancer Research40 ( 8 ) 4471 - 4479 2020年8月査読
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Okamoto M. . The chemokine receptor antagonist cenicriviroc inhibits the replication of SARS-CoV-2 in vitro . Antiviral Research182 104902 - 104902 2020年7月査読
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Samunuri R. . Synthesis and anti-HBV activity of carbocyclic nucleoside hybrids with salient features of entecavir and aristeromycin . RSC Medicinal Chemistry11 ( 5 ) 597 - 601 2020年5月査読
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Furukawa Y. . Successful treatment of an AIDS patient with prolonged Mycobacterium avium bacteremia, high HIV RNA, HBV infection, Kaposi's sarcoma and cytomegalovirus retinitis . Journal of Infection and Chemotherapy26 ( 2 ) 279 - 281 2020年2月招待 査読
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Tanishita S. . Cross-Protective Abilities of Hyaluronic Acid Modified with Tetraglycine- l -octaarginine as a Mucosal Adjuvant against Infection with Heterologous Influenza Viruses . Bioconjugate Chemistry30 ( 12 ) 3028 - 3037 2019年12月招待 査読
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Toyama M. . Pyrimidotriazine derivatives as selective inhibitors of HBV capsid assembly . Virus Research271 197677 - 197677 2019年10月招待 査読
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Ukawa M. . Biodegradable Hyaluronic Acid Modified with Tetraglycine- l -octaarginine as a Safe Adjuvant for Mucosal Vaccination . Molecular Pharmaceutics16 ( 3 ) 1105 - 1118 2019年3月招待 査読
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Okamoto M, Hidaka A, Toyama M, Baba M . Galectin-3 is involved in HIV-1 expression through NF-κB activation and associated with Tat in latently infected cells . Virus Research260 86 - 93 2019年1月査読
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Kumamoto H. . Synthesis, Anti-HBV, and Anti-HIV Activities of 3′-Halogenated Bis(hydroxymethyl)-cyclopentenyladenines . ACS Medicinal Chemistry Letters9 ( 12 ) 1211 - 1216 2018年12月招待 査読
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Sakurai Y, Sakakibara N, Toyama M, Baba M, Davey RA . Novel amodiaquine derivatives potently inhibit Ebola virus infection . Antiviral Research160 175 - 182 2018年12月査読
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Development of sugar chain-binding single-chain variable fragment antibody to adult T-cell leukemia cells using glyco-nanotechnology and phage display method . 163 ( 4 ) 281 - 291 2018年4月
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Effects of the Chemical Structures of Oligoarginines Conjugated to Biocompatible Polymers as a Mucosal Adjuvant on Antibody Induction in Nasal Cavities . 66 ( 4 ) 375 - 381 2018年4月
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Baba M, Toyama M, Sakakibara N, Okamoto M, Arima N, Saijo M . Establishment of an antiviral assay system and identification of severe fever with thrombocytopenia syndrome virus inhibitors . Antiviral Chemistry and Chemotherapy25 ( 3 ) 83 - 89 2017年12月査読
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Uto T. . Induction of innate and adaptive immunity with polyion complex nanoparticle adjuvant carrying human immunodeficiency virus type-1 gp120 . Journal of Biomedical Nanotechnology13 ( 7 ) 848 - 857 2017年7月
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Oyero OG, Toyama M, Mitsuhiro N, Onifade AA, Hidaka A, Okamoto M, Baba M . Selective inhibition of hepatitis C virus replication by Alpha-zam, a Nigella sativa seed formulation . African Journal of Traditional, Complementary and Alternative Medicines13 ( 6 ) 144 - 148 2016年9月査読
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Ito W, Toyama M, Okamoto M, Ikeda M, Watashi K, Wakita T, Hashimoto Y, Baba M . Isolation and characterization of hepatitis C virus resistant to a novel phenanthridinone derivative . Antiviral Chemistry and Chemotherapy24 ( 5-6 ) 148 - 154 2016年8月査読
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Uto T, Toyama M, Yoshinaga K, Baba M . Cepharanthine induces apoptosis through the mitochondria/caspase pathway in murine dendritic cells . Immunopharmacology and Immunotoxicology38 ( 3 ) 238 - 243 2016年1月査読
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Okamoto M, Hidaka A, Toyama M, Hosoya T, Yamamoto M, Hagiwara M, Baba M . Selective inhibition of HIV-1 replication by the CDK9 inhibitor FIT-039 . Antiviral Research123 1 - 4 2015年11月査読
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Uto T, Akagi T, Akashi M, Baba M . Induction of potent adaptive immunity by the novel polyion complex nanoparticles . Clinical Vaccine Immunology22 ( 5 ) 578 - 585 2015年5月査読
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Sakakibara N, Balboni G, Congiu C, Onnis V, Demizu Y, Misawa T, Kurihara M, Kato Y, Maruyama T, Toyama M, Okamoto M, Baba M . Design, synthesis, and anti-HIV-1 activity of 1-substituted 3-(3,5-dimethylbenzyl)triazine derivatives . Antiviral Chemistry and Chemotherapy24 ( 2 ) 62 - 71 2015年4月査読
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M. Toyama, H. Aoyama, R. Mukai, M. Nakamura, K. Yoshimura, M. Okamoto, T. Ohshima, Y. Hashimoto, Masanori Baba . A novel tetramethylnaphthalene derivative selectively inhibits adult T-cell leukemia (ATL) cells in vitro . Anticancer Research34 ( 4 ) 1771 - 1778 2014年4月査読
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馬場昌範 . エイズウイルス薬に関する研究の最前線 . 鹿児島大学医学部医師会報 ( 33 ) 48 - 49 2013年12月
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T. Hamasaki, M. Okamoto, Masanori Baba . Identification of novel inhibitors of human immunodeficiency virus type 1 replication by in silico screening targeting cyclin T1/Tat interaction . Antimicrobial Agents and Chemotherapy57 ( 3 ) 1323 - 1331 2013年5月査読
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M. Okamoto, H. Chono, Y. Kawano, N. Saito, H. Tsuda, K. Inoue, I. Kato, J. Mineno, Masanori Baba . Sustained inhibition of HIV-1 replication by conditional expression of the E. coli-derived endoribonuclease MazF in CD4+ T cells . Human Gene Therapy Methods24 ( 2 ) 94 - 103 2013年4月査読
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T. Uto, M. Toyama, Y. Nishi, T. Akagi, F. Shima, M. Akashi, Masanori Baba . Uptake of biodegradable poly(γ-glutamic acid) nanoparticles and antigen presentation by dendritic cells in vivo . Results in Immunology3 ( 1 ) 1 - 9 2013年1月査読
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M. Toyama, T. Hamasaki, T. Uto, H. Aoyama, M. Okamoto, Y. Hashimoto, Masanori Baba . Synergistic inhibition of HTLV-1-infected cell proliferation by combination of cepharanthine and a tetramethylnaphthalene derivative . Anticancer Research32 ( 7 ) 2639 - 2645 2012年7月査読
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P. Ordonez, T. Hamasaki, Y. Isono, N. Sakakibara, M. Ikejiri, T. Maruyama, Masanori Baba . Anti-human immunodeficiency virus type 1 activity of novel 6-substituted 1-benzyl-3-(3,5-dimethylbenzyl)uracil derivatives . Antimicrobial Agents and Chemotherapy56 ( 5 ) 2581 - 2589 2012年5月査読
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M.T. Salim, H. Aoyama, K. Sugita, K. Watashi, T. Wakita, T. Hamasaki, M. Okamoto, Y. Urata, Y. Hashimoto, Masanori Baba . Potent and selective inhibition of hepatitis C virus replication by novel phenanthridinone derivatives . Biochemical and Biophysical Research Communications415 ( 4 ) 714 - 718 2011年12月査読
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T. Uto, Y. Nishi, M. Toyama, K. Yoshinaga, Masanori Baba . Inhibitory effect of cepharanthine on dendritic cell activation and function . International Immunopharmacology11 ( 11 ) 1932 - 1938 2011年11月査読
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T. Uto, T. Akagi, M. Toyama, Y. Nishi, F. Shima, M. Akashi, Masanori Baba . Comparable activity of biodegradable nanoparticles with aluminum adjubvants: antigen uptake by dendritic cells and induction of immune response in mice . Immunology Letters140 ( 42006 ) 35 - 43 2011年10月査読
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T. Uto, T. Akagi, K. Yoshinaga, M. Toyama, M. Akashi, Masanori Baba . The induction of innate and adaptive immunity by biodegradable poly(γ-glutamic acid) nanoparticles via a TLR4 and MyD88 signaling pathway . Biomaterials32 ( 22 ) 5206 - 5212 2011年8月査読
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T. Hamasaki, M. Toyama, H. Aoyama, Y. White, M. Okamoto, N. Arima, Y. Hashimoto, Masanori Baba . Selective inhibition of HTLV-1-infected cell proliferation by a novel tetramethylnaphthalene derivative . Anticancer Research31 ( 6 ) 2241 - 2247 2011年6月査読
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M. T. A. Salim, Y. Goto, T. Hamasaki, M. Okamoto, H. Aoyama, Y. Hashimoto, S. Musiu, J. Paeshuyse, J. Neyts, M. Froeyen, P. Herdewijn, Masanori Baba . Highly potent and selective inhibition of bovine viral diarrhea virus replication by γ-carboline derivatives . Antiviral Research88 ( 3 ) 263 - 268 2010年12月査読
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T. Hamasaki, T. Uto, T. Akagi, M. Akashi, Masanori Baba . Modulation of gene expression related to Toll-like receptor signaling in dendritic cells by poly(γ-glutamic acid) nanoparticles . Clinical and Vaccine Immunology17 ( 5 ) 748 - 756 2010年5月査読
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M. T. A. Salim, M. Okamoto, S. Hosoda, H. Aoyama, Y. Hashimoto, Masanori Baba . Anti-bovine viral diarrhoea virus activity of novel diphenylmethane derivatives . Antiviral Chemistry & Chemotherapy20 ( 5 ) 193 - 200 2010年4月査読
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M. Okamoto, M. Sakai, Y. Goto, M. T. A. Salim, C. Baba, K. Goto, K. Watashi, K. Shimotohno, Masanori Baba . Anti-bovine viral diarrhea virus and hepatitis C virus activity of the cyclooxygenase inhibitor SC-560 . Antiviral Chemistry & Chemotherapy20 ( 1 ) 47 - 54 2009年9月査読
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M. Shi, X. Wang, M. Okamoto, S. Takao, Masanori Baba . Inhibition of porcine endogenous retrovirus (PERV) replication by HIV-1 gene expression inhibitors . Antiviral Research83 ( 2 ) 201 - 204 2009年8月査読
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T. Uto, T. Akagi, T. Hamasaki, M. Akashi, Masanori Baba . Modulation of innate and adaptive immunity by biodegradable nanoparticles . Immunology Letters125 ( 1 ) 46 - 52 2009年6月査読
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T. Uto, X. Wang, T. Akagi, R. Zenkyu, M. Akashi, Masanori Baba . Improvement of adaptive immunity by antigen-carrying biodegradable nanoparticles . Biochemical and Biophysical Research Communications379 ( 2 ) 600 - 604 2009年2月査読
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Masanori Baba, M. Okamoto, T. Hamasaki, S. Horai, X. Wang, Y. Ito, Y. Suda, N. Arima . Highly enhanced expression of CD70 on human T-lymphotropic virus type 1-carrying cell lines and adult T-cell leulemia cells . Journal of Virology82 ( 8 ) 3843 - 3852 2008年4月査読
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X. Wang, T. Uto, T. Akagi, M. Akashi, Masanori Baba . Poly(γ-glutamic acid) nanoparticles as an efficient antigen delivery and adjuvant system: potential for an anti-AIDS vaccine . Journal of Medical Virology80 ( 1 ) 11 - 19 2008年1月査読
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X. Wang, T. Uto, T. Akagi, M. Akashi, Masanori Baba . Induction of potent CD8+ T-cell responses by novel biodegradable nanoparticles carrying human immunodeficiency virus type 1 gp120 . Journal of Virology81 ( 18 ) 10009 - 10016 2007年9月査読
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X. Wang, K. Yamataka, M. Okamoto, S. Ikeda, Masanori Baba . Potent and selective inhibition of Tat-dependent HIV-1 replication in chronically infected cells by a novel naphtalene derivative JTK-101 . Antivral Chemistry and Chemotherapy18 ( 4 ) 201 - 211 2007年8月査読
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M. Shi, X. Wang, E. De Clercq, S. Takao, Masanori Baba . Selective inhibition of porcine endogenous retrovirus (PERV) replication in human cells by acyclic nucleoside phosphonates . Antimicrobial Agents and Chemotherapy51 ( 7 ) 2600 - 2604 2007年7月査読
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T. Uto, X. Wang, K. Sato, M. Haraguchi, T. Akagi, M. Akashi, Masanori Baba . Targeting of antigen to dendritic cells with poly(γ-glutamic acid) nanoparticles induces antigen-specific humoral and cellular immunity . The Journal of Immunology178 ( 5 ) 2979 - 2986 2007年3月査読
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Masanori Baba, H. Miyake, X. Wang, M. Okamoto, K. Takashima . Isolation and characterization of human immunodeficiency virus type 1 resistant to the small-molecule CCR5 antagonist TAK-652 . Antimicribial Agents and Chemotherapy51 ( 2 ) 707 - 715 2007年2月査読
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M. Okamoto, X. Wang, Masanori Baba . HIV-1-infected macrophages induce astrogliosis by SDF-1alpha and matrix metalloproteinases . Biochemical and Biophysical Research Communications336 ( 4 ) 1214 - 1220 2005年11月査読
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Masanori Baba, K. Takashima, H. Miyake, N. Kanzaki, K. Teshima, X. Wang, M. Shiraishi, Y. Iizawa . TAK-652 inhibits CCR5-mediated HIV-1 infection in vitro and has favorable pharmacokinetics in humans . Antimicrobial Agents and Chemotherapy49 ( 11 ) 4584 - 4591 2005年11月査読
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K. Takashima, H. Miyake, N. Kanzaki, Y. Tagawa, X. Wang, Y. Sugihara, Y. Iizawa, Masanori Baba . Highly potent inhibition of human immunodeficiency virus type 1 replication by TAK-220, an orally bioavailable small molecule CCR5 antagonist . Antimicrobial Agents and Chemotherapy49 ( 8 ) 3474 - 3482 2005年8月査読
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T. Nitanda, X. Wang, H. Kumamoto, K. Haraguchi, H. Tanaka, Y.-C. Cheng, Masanori Baba . Anti-human immunodeficiency virus type 1 activity and resistance profile of 2',3'-didehydro-3'-deoxy-4'-ethynylthymidine in vitro . Antimicrobial Agents and Chemotherapy49 ( 8 ) 3355 - 3360 2005年8月査読
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M. Kawamura, X. Wang, T. Uto, K. Sato, M. Ueno, M. Akagi, K. Hiraishi, T. Matsuyama, M. Akashi, Masanori Baba . Induction of dendritic cell-mediated immune responses against HIV-1 by antigen-capturing nanospheres in mice . Journal of Medical Virology76 ( 1 ) 7 - 15 2005年5月査読
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X. Wang, T. Uto, K. Sato, K. Ide, T. Akagi, M. Okamoto, T. Kaneko, M. Akashi, Masanori Baba . Potent activation of antigen-specific T cells by antigen-loaded nanospheres . Immunology Letters98 ( 1 ) 123 - 130 2005年4月査読
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C. Baba, K. Yanagida, T. Kanzaki, Masanori Baba . CCR5 antagonists as anti-HIV-1 agents. Part 3: Synthesis and biological evaluation of piperidine-4-carboxamide derivatives . Antiviral Chemistry & Chemotherapy16 ( 1 ) 397 - 416 2005年2月査読
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K. Yanagida, C. Baba, Masanori Baba . Inhibition of bovine viral diarrhea virus (BVDV) by mizoribine: Synergistic effect of combination with interferon-alpha . Antiviral Research64 ( 3 ) 195 - 201 2004年12月査読
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X. Wang, T. Nitanda, M. Shi, M. Okamoto, T. Furukawa, Y. Sugimoto, S. Akiyama, Masanori Baba . Induction of cellular resistance to nucleoside reverse transcriptase inhibitors by the wild-type breast cancer resistance protein . Biochemical Pharmacology68 ( 7 ) 1363 - 1370 2004年10月査読