Updated on 2026/09/16
マルチオミクス
THE JAPAN NEUROSCIENCE SOCIETY researchmap
Fusako Kojima, So Morishita, Shinsuke Uda, Noriko Yutsudo, Yoshihiro Ogawa, Hiroyuki Kubota . Evaluation of the insulin-dependent and -independent hypoglycemic effects and understanding their breakdown in the progression of obesity using mice . PLOS One20 ( 12 ) e0337739 - e0337739 2025.12Reviewed
Song Qi, Zixuan Liu, Keitaro Suyama, Yuichi Tsuchiya, Jedidiah Canarejo, Khanh Quoc Phan, Noriko Yutsudo, Atsushi Shimada, Takeshi Hirota, Ichiro Ieiri, Akihiro Kishimura, Takahiro Muraoka, Takeru Nose, Takeshi Mori, Yoshiki Katayama . Ligand Design with Accelerated Disulfide Formation with Serum Albumin to Extend Blood Retention . ACS Medicinal Chemistry Letters16 ( 1 ) 144 - 148 2024.12Reviewed
Noriko Yutsudo, Hiroshi Kitagawa . Involvement of chondroitin 6-sulfation in temporal lobe epilepsy . EXPERIMENTAL NEUROLOGY274 126 - 133 2015.12Reviewed
Noriko Yutsudo, Takashi Kamada, Kosuke Kajitani, Hiroko Nomaru, Atsuhisa Katogi, Yoko H. Ohnishi, Yoshinori N. Ohnishi, Kei Ichiro Takase, Sakumi Kunihiko, Hiroshi Shigeto, Yusaku Nakabeppu . Erratum FosB-null mice display impaired adult hippocampal neurogenesis and spontaneous epilepsy with depressive behavior (Neuropsychopharmacology (2013) 38 (1374-1375) DOI: 10.1038/npp.2013.56) . Neuropsychopharmacology38 ( 7 ) 1374 - 1375 2013.6Reviewed
Noriko Yutsudo, Takashi Kamada, Kosuke Kajitani, Hiroko Nomaru, Atsuhisa Katogi, Yoko H. Ohnishi, Yoshinori N. Ohnishi, Kei-ichiro Takase, Kunihiko Sakumi, Hiroshi Shigeto, Yusaku Nakabeppu . fosB-Null Mice Display Impaired Adult Hippocampal Neurogenesis and Spontaneous Epilepsy with Depressive Behavior . NEUROPSYCHOPHARMACOLOGY38 ( 5 ) 895 - 906 2013.4Reviewed
Kyota Fujita, Toshihiro Seike, Noriko Yutsudo, Mizuki Ohno, Hidetaka Yamada, Hiroo Yamaguchi, Kunihiko Sakumi, Yukiko Yamakawa, Mizuho A. Kido, Atsushi Takaki, Toshihiko Katafuchi, Yoshinori Tanaka, Yusaku Nakabeppu, Mami Noda . Hydrogen in Drinking Water Reduces Dopaminergic Neuronal Loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Mouse Model of Parkinson's Disease . PLOS ONE4 ( 9 ) e7247 2009.9Reviewed
K. Kajitani, H. Nomaru, M. Ifuku, N. Yutsudo, Y. Dan, T. Miura, D. Tsuchimoto, K. Sakumi, T. Kadoya, H. Horie, F. Poirier, M. Noda, Y. Nakabeppu . Galectin-1 promotes basal and kainate-induced proliferation of neural progenitors in the dentate gyrus of adult mouse hippocampus . CELL DEATH AND DIFFERENTIATION16 ( 3 ) 417 - 427 2009.3Reviewed
ペプチド医薬の超長期血中滞留を可能にするヒト血清アルブミンへのリガンド 脂肪酸結合ポケットとCys34の活用
江橋 勧, Qi Song, Liu Zixuan, 巣山 慶太郎, 土谷 祐一, 湯通堂 紀子, 嶋田 睦, 廣田 豪, 家入 一郎, 岸村 顕広, 野瀬 健, 森 健, 片山 佳樹
日本DDS学会学術集会プログラム予稿集 2025.6
Comprehensive analysis of gene expression profiles regulated by fosB gene in brain
Hiroko Nomaru, Yoshinori N. Ohnishi, Masaaki Hokama, Noriko Yutsudo, Yusaku Nakabeppu
NEUROSCIENCE RESEARCH 71 E121 - E121 2011
Delta FosB and/or Delta 2 Delta FosB regulate proliferation of adult hippocampal neural progenitor cells and suppress spontaneous epileptic seizures
Noriko Yutsudo, Takashi Kamada, Hiroko Nomaru, Yoko H. Ohnishi, Yoshinori N. Ohnishi, Kosuke Kajitani, Kunihiko Sakumi, Hiroshi Shigeto, Yusaku Nakabeppu
NEUROSCIENCE RESEARCH 71 E295 - E295 2011
fosB欠損マウスは成体海馬における神経新生の低下を示し、てんかんを自然発症する(fosB-null mice exhibit impaired adult hippocampal neurogenesis and spontaneous epileptic seizures)
湯通堂 紀子, 鎌田 崇嗣, 大西 陽子[本田], 大西 克典, 梶谷 康介, 作見 邦彦, 重藤 寛史, 中別府 雄作
神経化学 49 ( 2-3 ) 753 - 753 2010.8
fosB-null mice exhibit impaired adult hippocampal neurogenesis and spontaneous epileptic seizures
Yutsudo Noriko, Kamada Takashi, Honda-Ohnishi Yoko, Ohnishi Yoshinori, Kajitani Kosuke, Sakumi Kunihiko, Shigeto Hiroshi, Nakabeppu Yusaku
NEUROSCIENCE RESEARCH 68 E419 2010
Poor proliferation of neural progenitors in the dentate gyrus of hippocampus in adult fosB-null mice exhibiting increased susceptibility for spontaneous epileptic seizures
Yutsudo Noriko, Kamada Takashi, Honda-Ohnisi Yoko, Ohnishi Yoshi-Nori, Kajitani Kosuke, Sakumi Kunihiko, Shigeto Hirsohi, Nakabeppu Yusaku
NEUROSCIENCE RESEARCH 65 S251 2009
Delta FosB promotes neurogenesis in the dentate gyrus of mouse hippocampus
Noriko Yutsudo, Yoko Dhnishi-Honda, Yoshinori Dhnishi, Kunihiko Sakumi, Yusaku Nakabeppu
NEUROSCIENCE RESEARCH 61 S95 - S95 2008
Delta FosB promotes neurogenesis in the dentate gyrus of mouse hippocampus after brain damage caused by excitotoxicity
Noriko Yutsudo, Yoko Honda-Ohnishi, Yoshinori Ohnishi, Yusaku Nakabeppu
NEUROSCIENCE RESEARCH 58 S210 - S210 2007
Transcription factor Nrf2 regulates brain response to kainate-induced excitotoxicity
Dan Yukihiko, Kajitani Kosuke, Yutsudo Noriko, Itoh Ken, Yamamoto Masayuki, Nakabeppu Yusaku
NEUROSCIENCE RESEARCH 55 S137 2006
Noriko Yutsudo ΔFosB and/or Δ2ΔFosB regulate proliferation of adult hippocampal neural progenitor cells and suppress spontaneous epileptic seizures (short talk) International conference
Neurogenesis 2011 in Kobe 2011.6
Noriko Yutsudo fosB-null mice display impaired adult hippocampal neurogenesis and spontaneous epilepsy with depressive behavior
OIST Seminar 2014.5
肥満から前糖尿病段階におけるミトコンドリア代謝経路の時系列・多階層数理解析
Grant number：20K17537 2020.4 - 2022.3
日本学術振興会 科学研究費助成事業 若手研究 若手研究
湯通堂 紀子
Authorship：Principal investigator
Grant amount：\4160000 （ Direct Cost: \3200000 、 Indirect Cost：\960000 ）
インスリン抵抗性発症過程におけるミトコンドリア酸化的リン酸化の時系列オミクス解析
Grant number：18K16207 2018 - 2019
日本学術振興会 科学研究費助成事業 若手研究
Authorship：Principal investigator Grant type：Competitive
Grant amount：\4160000 （ Direct Cost: \3200000 、 Indirect Cost：\960000 ）
Regulatory mechanisms of neuronal activity by chondroitin sulfate chains
Grant number：23110003 2011.4 - 2016.3
Japan Society for the Promotion of Science Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
Kitagawa Hiroshi, TAMURA Jun-ichi, NADANAKA Satomi, MIKAMI Tadahisa, MIYATA Shinji, SATO Ban, HIRAOKA Syuichi, KITAZAWA Kazuyuki, EIRAKU Hoshiko, YUZUDOU Noriko, SIDA Miharu
Grant amount：\127270000 （ Direct Cost: \97900000 、 Indirect Cost：\29370000 ）
Chondroitin sulfate (CS), a major component of the brain extracellular matrix, is reported to play a role in controlling critical period plasticity. Digestion of CS chains has shown to restore visual cortical plasticity in adult animals, but the underlying mechanisms remain unknown. CS chain is a linear polysaccharide consisting of repeating disaccharide units that can be substituted with sulfate groups at various positions, thereby producing characteristic sulfation patterns. Thus we hypothesized that sulfation patterns of CS chains regulate the critical period plasticity. Using transgenic mouse model overexpressing chondroitin 6-sulfotransferase-1, we found that a developmental increase in the 4-sulfation/6-sulfation ratio of CS chains leads to the termination of the critical period in the mouse visual cortex. These results suggest that specific sulfation patterns of CS chains regulate the maturation of parvalbumin-expressing interneurons.
平成22年度研究助成（海外渡航費）
財団法人遺伝学普及会
