Updated on 2023/10/23

写真a

 
KEDOIN Chihiro
 
Organization
University Hospital, Medical and Dental Sciences Area University Hospital Clinical Facilities Perinatal Center Assistant Professor
Title
Assistant Professor
 

Papers

  • Nagano A., Sugita K., Harumatsu T., Nishida N., Kedoin C., Murakami M., Yano K., Onishi S., Matsukubo M., Kawano T., Muto M., Torikai M., Kaji T., Ieiri S. .  Predictive factors of bowel resection for midgut volvulus based on an analysis of bi-center experiences in southern Japan .  Pediatric Surgery International39 ( 1 ) 113   2023.12

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    Language:Japanese   Publisher:Pediatric Surgery International  

    Purpose: Midgut volvulus is an urgent disease often occurring in neonates. This study clarified the clinical features of midgut volvulus and evaluated predictors to avoid bowel resection. Methods: This bi-center retrospective study enrolled 48 patients who underwent surgery for intestinal malrotation between 2010 and 2022. Patients’ background characteristics and preoperative imaging findings were reviewed. Results: Midgut volvulus was recognized in 32 patients (66.7%), and 6 (12.5%) underwent bowel resection. Based on a receiver operating curve analysis of bowel resection, the cut-off value of the body weight at birth and at operation were 1984 g [area under the curve (AUC) 0.75, 95% confidence interval (CI) 0.52–0.99] and 2418 g (AUC 0.70, 95% CI 0.46–0.94), respectively. The cut-off value of intestinal torsion was 540° (AUC 0.76, 95% CI 0.57–0.95), and that of the time from the onset to the diagnosis was 12 h (AUC 0.85, 95% CI 0.72–0.98). For midgut volvulus with an intestinal torsion > 540°, the most sensitive preoperative imaging test was ultrasonography (75%) Patients with bloody stool tended to undergo bowel resection. Conclusions: Patients with a low body weight and bloody stool should be confirmed to have whirlpool sign by ultrasonography and scheduled for surgery as soon as possible.

    DOI: 10.1007/s00383-023-05406-0

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  • Nagano A., Harumatsu T., Sugita K., Iwamoto Y., Ogata M., Takada L., Nishida N., Kedoin C., Murakami M., Yano K., Onishi S., Yamada K., Yamada W., Kawano T., Muto M., Kaji T., Ieiri S. .  Change over time in the postoperative defecation function in female patients with anovestibular fistula at a single institution: focus on the comparison of anal transposition with anterior sagittal anorectoplasty .  Pediatric Surgery International39 ( 1 ) 266   2023.12

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    Language:Japanese   Publisher:Pediatric Surgery International  

    Purpose: Anovestibular fistula (AVF) is the most common type of ARM in female patients. The present study investigated changes over time in the postoperative defecation function of female patients with AVF. Methods: Patient data were collected from 1984 to 2021. Eighty-eight female patients with AVF were enrolled. Patients’ characteristics and the long-term outcome of defecation function were reviewed and analyzed retrospectively. The bowel function was evaluated according to the Japan Society of ARM Study Group evacuation score (ES). Results: Thirty-eight patients underwent anal transposition (AT), and 8 underwent anterior sagittal anorectoplasty (ASARP). The total evacuation score (ES) in AVF patients reached “excellent” at nine years old, regardless of the operative procedure. The constipation scores with AT showed better improvement than those with ASARP, but soiling scores in the ASARP group showed better improvement than those in the AT group. The postoperative complications did not affect the postoperative bowel function in AVF patients. Conclusion: Most patients with AVF eventually achieved a satisfactory total ES. Given the difference in defecation score transition depending on the operative procedure or postoperative complications, it may be important to perform long-term defecation management via surgical procedures.

    DOI: 10.1007/s00383-023-05554-3

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  • Sugita Koshiro, Kawano Takafumi, Murakami Masakazu, Nishida Nanako, Kedoin Chihiro, Nagano Ayaka, Yano Keisuke, Onishi Shun, Harumatsu Toshio, Yamada Koji, Yamada Waka, Matsukubo Makoto, Muto Mitsuru, Kaji Tatsuru, Ieiri Satoshi .  Feasible laparoscopic surgery for selected cases of primary adrenal neuroblastoma: Results from a comparison with open surgery at a single institution(タイトル和訳中) .  Asian Journal of Endoscopic Surgery16 ( 3 ) 473 - 481   2023.7Feasible laparoscopic surgery for selected cases of primary adrenal neuroblastoma: Results from a comparison with open surgery at a single institution(タイトル和訳中)

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    Language:English   Publisher:John Wiley & Sons Australia, Ltd  

  • Sugita K., Kawano T., Murakami M., Nanako N., Kedoin C., Nagano A., Yano K., Onishi S., Harumatsu T., Yamada K., Yamada W., Matsukubo M., Muto M., Kaji T., Ieiri S. .  Feasible laparoscopic surgery for selected cases of primary adrenal neuroblastoma: Results from a comparison with open surgery at a single institution .  Asian Journal of Endoscopic Surgery16 ( 3 ) 473 - 481   2023.7

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    Language:Japanese   Publisher:Asian Journal of Endoscopic Surgery  

    Introduction: Surgical management of neuroblastoma (NB) has been performed by open procedures for decades. However, advances in surgical devices and technology have made minimally invasive surgery safe and reproducible. In this study, we compared open and laparoscopic surgery regarding biopsy success and curative resection to determine the safety and feasibility of laparoscopic surgery for pediatric patients with adrenal NB. Methods: We reviewed the clinical data of 22 NB patients who underwent surgery from 2006 to 2021 in our institution. All patients with adrenal NB were diagnosed histologically, and we retrospectively analyzed the data. Results: The male/female ratio was 16/6. The median age was 2.5 (interquartile range: 2–4) years old, and the laterality was on the right in 13 and on the left in 9. A total of 20 patients underwent a tumor biopsy: 14 via laparotomy, five laparoscopically, and one retroperitoneally. Four patients underwent laparoscopic resection and 11 patients underwent open resection after chemotherapy. Two patients with stage LI underwent primary tumor resection laparoscopically. For curative resection in image-defined risk factor (IDRF)-negative patients, laparoscopic surgery resulted in shorter operation time, with less bleeding and an earlier oral intake. The three IDRF-single-positive patients on the liver (laparoscopic surgery: one patient) had a shorter operation time and less bleeding than the IDRF-multiple positive patients. Conclusion: Laparoscopic surgery was performed in a limited number of adrenal NB cases. A laparoscopic biopsy for adrenal NB seems to be safe and feasible to perform. Laparoscopic surgery, in carefully selected cases, permits safe and efficient resection of adrenal NB in pediatric patients.

    DOI: 10.1111/ases.13204

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  • 武藤 充, 大西 峻, 矢野 圭輔, 高田 倫, 岩元 祐実子, 緒方 将人, 祁答院 千寛, 村上 雅一, 杉田 光士郎, 春松 敏夫, 川野 孝文, 大浦 飛鳥, 東小薗 未弥子, 佐々木 文郷, 西川 拓朗, 上村 修司, 家入 里志 .  特集 今日の小児肝移植 非移植施設からみた肝移植の課題について-肝小腸異時移植症例の管理経験から- .  小児外科55 ( 6 ) 684 - 688   2023.6

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    Publisher:東京医学社  

    DOI: 10.24479/ps.0000000493

  • Matsukubo M, Muto M, Yamada K, Nishida N, Kedoin C, Matsui M, Nagano A, Murakami M, Sugita K, Yano K, Onishi S, Harumatsu T, Yamada W, Kawano T, Kaji T, Ieiri S .  Abdominal wall defect repair with component separation technique for giant omphalocele with previous relaxing incisions on the abdominal skin. .  Surgical case reports9 ( 1 ) 99   2023.6Abdominal wall defect repair with component separation technique for giant omphalocele with previous relaxing incisions on the abdominal skin.

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    DOI: 10.1186/s40792-023-01679-8

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  • Matsukubo Makoto, Muto Mitsuru, Yamada Koji, Nishida Nanako, Kedoin Chihiro, Matsui Mayu, Nagano Ayaka, Murakami Masakazu, Sugita Koshiro, Yano Keisuke, Onishi Shun, Harumatsu Toshio, Yamada Waka, Kawano Takafumi, Kaji Tatsuru, Ieiri Satoshih .  Abdominal wall defect repair with component separation technique for giant omphalocele with previous relaxing incisions on the abdominal skin(タイトル和訳中) .  Surgical Case Reports9   1 of 5 - 5 of 5   2023.6Abdominal wall defect repair with component separation technique for giant omphalocele with previous relaxing incisions on the abdominal skin(タイトル和訳中)

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    Language:English   Publisher:Springer Berlin Heidelberg  

  • Matsukubo M, Muto M, Onishi S, Nishida N, Kedoin C, Nagano A, Matsui M, Murakami M, Sugita K, Yano K, Harumatsu T, Yamada K, Yamada W, Kawano T, Kaji T, Ieiri S .  Safe and secure laparoscopy-assisted jejunostomy tube placement using a percutaneous loop needle device in an infant. .  Journal of minimal access surgery   2023.5Safe and secure laparoscopy-assisted jejunostomy tube placement using a percutaneous loop needle device in an infant.

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    DOI: 10.4103/jmas.jmas_10_23

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  • 家入 里志, 山田 耕嗣, 大西 峻, 村上 雅一, 矢野 圭輔, 岩元 祐実子, 緒方 将人, 高田 倫, 祁答院 千寛, 杉田 光士郎, 春松 敏夫, 山田 和歌, 川野 孝文, 武藤 充 .  特集 ロボット支援手術 小児外科領域における次世代手術支援ロボット開発-Soft Roboticsの可能性- .  小児外科55 ( 5 ) 525 - 531   2023.5

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    Publisher:東京医学社  

    DOI: 10.24479/ps.0000000445

  • Muto M., Murakami M., Masuya R., Fukuhara M., Shibui Y., Nishida N., Kedoin C., Nagano A., Sugita K., Yano K., Onishi S., Harumatsu T., Yamada K., Yamada W., Kawano T., Matsukubo M., Izaki T., Nakame K., Kaj T., Hirose R., Nanashima A., Ieiri S. .  Feasibility of Laparoscopic Fundoplication Without Removing the Preceding Gastrostomy in Severely Neurologically Impaired Patients: A Multicenter Evaluation of the Traction Technique .  Journal of Laparoendoscopic and Advanced Surgical Techniques33 ( 5 ) 518 - 521   2023.5

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    Language:Japanese   Publisher:Journal of Laparoendoscopic and Advanced Surgical Techniques  

    Purpose: Severely neurologically impaired patients sometimes require anti-reflux surgery with preceding gastrostomy. We apply a traction technique for laparoscopic fundoplication (LF) without gastrostomy takedown (GTD) in such cases. We conducted a multicenter review to assess the feasibility of our approach. Materials and Methods: In brief, the traction technique involves left-lateral-traction of the stomach body, right-lateral-traction of the round ligament of the liver, and elevation of the left liver lobe to create a sufficient field for manipulating the forceps. Patients who underwent LF with Nissen's procedures in 2010-2022 were retrospectively reviewed. Data were analyzed by a one-way analysis of variance. Results: The operative approaches included the traction technique (n = 16; Group 1), GTD and reconstruction (n = 5; Group 2), and LF followed by gastrostomy (n = 92; Group 3). In comparison with Group 1, significant differences were only found in pneumoperitoneum time (Group 1 versus Group 2 versus Group 3: 174.4 minutes versus 250.4 minutes versus 179.5 minutes; P = .0179). Operating time (222.7 minutes versus 303.0 minutes versus 239.7 minutes; P = .0743), duration to full-strength enteral nutrition (10.4 days versus 17.2 days versus 11.0 days; P = .0806), and length of hospital stay (17.2 days versus 31.0 days versus 18.5 days; P = .3247) were equivalent. No re-fundoplication was required in Group 1. Conclusion: The traction technique secures the operative quality and outcome of LF without GTD.

    DOI: 10.1089/lap.2022.0576

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  • 大西 峻, 西田 ななこ, 祁答院 千寛, 長野 綾香, 村上 雅一, 杉田 光士郎, 春松 敏夫, 川野 孝文, 武藤 充, 家入 里志 .  特集 どうする? 小児の便秘・下痢 便秘の原因となる器質的疾患の診断と長期的な治療戦略 Hirschsprung病 .  小児内科55 ( 3 ) 385 - 389   2023.3

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    Publisher:東京医学社  

    DOI: 10.24479/pm.0000000804

  • Onishi S., Muto M., Kedoin C., Yamada T., Ieiri S. .  Detecting congenital subglottic stenosis using ultrasonography examination .  Pediatrics International65 ( 1 ) e15579   2023.1

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    Language:Japanese   Publisher:Pediatrics International  

    DOI: 10.1111/ped.15579

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  • Masuya R., Muraji T., Harumatsu T., Machigashira S., Iwamoto Y., Ogata M., Takada L., Nishida N., Kedoin C., Nagano A., Matsui M., Murakami M., Sugita K., Yano K., Onishi S., Yamada K., Yamada W., Matsukubo M., Kawano T., Muto M., Nakame K., Kaji T., Nanashima A., Ieiri S. .  Clinical outcome and neurological development of patients with biliary atresia associated with a bleeding tendency: a single institution experience .  Surgery Today   2023

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    Language:Japanese   Publisher:Surgery Today  

    Purpose: We compared the clinical features of patients with biliary atresia (BA) associated with a bleeding tendency (BT) at the time of the diagnosis with those of patients without a bleeding tendency (NBT). Methods: The patients’ background characteristics, age in days at the first visit, Kasai portoenterostomy (KPE), and postoperative course were retrospectively analyzed. Results: Nine of the 93 BA patients (9.7%) showed a BT, including 7 with intracranial hemorrhaging (ICH), 1 with gastrointestinal bleeding, and 1 with a prothrombin time (PT) of 0%. The age at the first visit was 62 ± 12 days old for BT patients and 53 ± 27 days old for NBT patients (p = 0.4); the age at KPE was 77 ± 9 days old for BT patients and 65 ± 24 days old for NBT patients (p = 0.2); the time from the first visit to surgery was 13 ± 7 days for BT patients and 11 ± 10 days for NBT patients (p = 0.5); and the native liver survival rate was 56% for BT patients and 58% for NBT patients (p = 1), with no significant difference in any of the parameters. The neurological outcomes of survivors of ICH were favorable. Conclusions: Appropriate BT correction allowed early KPE even after ICH, resulting in native liver survival rates comparable to those of NBT patients without significant neurological complications.

    DOI: 10.1007/s00595-023-02744-3

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  • Onishi S., Kawano T., Nishida N., Kedoin C., Nagano A., Murakami M., Sugita K., Harumatsu T., Muto M., Ieiri S. .  Case report: Minimal tissue damage and low coagulation liver resection for hepatoblastoma using indocyanine green fluorescence and water-jet dissector .  Frontiers in Pediatrics11   1221596   2023

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    Language:Japanese   Publisher:Frontiers in Pediatrics  

    Near-infrared (NIR) fluorescence imaging with indocyanine green (ICG) has gained popularity in pediatric surgery as it has in general surgery. In addition, a water-jet dissector (WJD) has been successfully introduced in adult hepatic surgery. Tissue structures are dissected selectively and gently by the WJD. However, there have been no reports of hepatic resection for pediatric patients using a WJD. We applied NIR fluorescence imaging with ICG to visualize the resection line of the liver and used a WJD for liver parenchyma dissection in pediatric hepatoblastoma. The patient was a 3-year-old girl with a large liver tumor. Enhanced computed tomography revealed a liver tumor (maximum diameter: 120 mm) in the right lobe and three small lung metastases. The liver tumor was diagnosed as hepatoblastoma (PRETEXT 2) based on an open biopsy. We performed right hepatectomy after neoadjuvant chemotherapy. The right lobe was mobilized from the diaphragm, and then intraoperative ultrasound was performed to detect the localization of the tumor and its proximity to the vascular structures. We detected the right hepatic artery (RHA), right portal vein (RPV), and right hepatic vein (RHV). The middle hepatic vein was not involved. After ligation of the RHA and RPV to selectively control the right lobe inflow, ICG was administered intravenously and observed by an NIR endoscope. The resection line was clearly visualized by overlaying images in comparison to conventional demarcation line detection. Then, we used a WJD to dissect the parenchyma. Small vessels were divided from parenchymal tissue and were clearly visible. We resected them after clamping with metal clips. Finally, the RHV was transected by a linear stapler, and right hepatectomy was completed with 25 ml of blood loss. There was no postoperative hemorrhage. We performed hepaticojejunostomy because of stricture of the common bile duct on postoperative day 302. The patient was discharged after adjuvant chemotherapy. NIR imaging clearly showed the resection line. The WJD automatically separated, and thus made visible, the more resistant duct and vessel structures from the parenchyma. The combined use of NIR imaging and WJD was useful for pediatric hepatectomy.

    DOI: 10.3389/fped.2023.1221596

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  • Yano K., Muto M., Nagai T., Harumatsu T., Kedoin C., Nagano A., Matsui M., Murakami M., Sugita K., Onishi S., Yamada K., Yamada W., Matsukubo M., Kaji T., Ieiri S. .  The analgesic effect of the intravenous administration of acetaminophen for pediatric laparoscopic appendectomy: A comparison of scheduled and on-demand procedures .  Asian Journal of Endoscopic Surgery15 ( 4 ) 715 - 721   2022.10

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    Language:Japanese   Publisher:Asian Journal of Endoscopic Surgery  

    Purpose: The intravenous administration of acetaminophen (IAA) has become standard postoperative analgesic management for pediatric surgery. However, the most effective methods of IAA for postoperative acute appendicitis are unclear. We evaluated the analgesic efficacy of scheduled IAA vs on-demand IAA for postoperative acute appendicitis. Methods: Ninety-four patients who underwent laparoscopic appendectomy in our institution between January 2017 and December 2020 were enrolled. The patients were divided into two groups based on the postoperative pain control protocols. The scheduled IAA group (SA group, n = 42) was managed by scheduled IAA and additional on-demand use of pentazocine as rescue therapy. The on-demand IAA group (ODA group, n = 52) was managed by on-demand IAA as the first choice, with pentazocine as the second choice for pain control. The patients' background characteristics, operative results and postoperative outcomes were reviewed. Results: The number of times pain complaints were made per patient per day (NPPD) on postoperative days (POD) 1 and 2 was significantly lower in the SA group than in the ODA group (POD 1; 1.12 ± 1.21 vs 2.62 ± 1.89, p < 0.01; POD 2; 0.45 ± 0.86 vs. 1.31 ± 1.69, p < 0.01). According to pathological findings, NPPD was lower in the SA group than in the ODA group for both phlegmonous appendicitis (0.71 ± 1.01 vs. 2.10 ± 2.13, P <.05) and gangrenous appendicitis (1.33 ± 1.50 vs 2.94 ± 1.68, P <.01). On POD 2, the incidence of gangrenous appendicitis was significantly lower in the SA group than in the ODA group (0.57 ± 0.93 vs 1.78 ± 1.86, P <.01). Conclusions: Scheduled IAA may have favorable efficacy for postoperative pain control after emergency surgery for acute appendicitis in pediatric patients.

    DOI: 10.1111/ases.13068

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  • Murakami Masakazu, Muto Mitsuru, Nakagawa Shunsuke, Kedoin Chihiro, Matsui Mayu, Sugita Koshiro, Yano Keisuke, Onishi Shun, Harumatsu Toshio, Yamada Koji, Yamada Waka, Matsukubo Makoto, Kawano Takafumi, Kodama Yuichi, Nishikawa Takuro, Kaji Tatsuru, Okamoto Yasuhiro, Ieiri Satoshi .  上行結腸に浸潤し多発性リンパ節転移を有する巨大大網悪性リンパ腫に対する腹腔鏡下拡大切除の奏効例 高度な手技を要した小児の1例(Successful laparoscopy-assisted en bloc resection of bulky omental malignant lymphoma involving the ascending colon and multiple lymph node metastases: Report of a technically demanding case in a pediatric patient) .  Asian Journal of Endoscopic Surgery15 ( 4 ) 836 - 840   2022.10上行結腸に浸潤し多発性リンパ節転移を有する巨大大網悪性リンパ腫に対する腹腔鏡下拡大切除の奏効例 高度な手技を要した小児の1例(Successful laparoscopy-assisted en bloc resection of bulky omental malignant lymphoma involving the ascending colon and multiple lymph node metastases: Report of a technically demanding case in a pediatric patient)

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    Language:English   Publisher:John Wiley & Sons Australia, Ltd  

    症例は13歳男児で、腹痛と触知可能な腫瘤を呈し、造影CTで上行結腸に浸潤する最大径13cmの巨大腹部腫瘍を認め、バリウム注腸にて上行結腸の重度狭窄がみられた。PET-CTで多発性腹部リンパ節転移が検出され、MRIでは腫瘍は大網に起源し、T1強調像にて軽度低信号、T2強調像にて軽度高信号を呈していた。大網に生じる線維形成性小円形細胞腫瘍が考えられ、鑑別疾患としてリンパ腫、結核性腹膜炎が挙げられた。腹腔鏡下手術を行うこととし、腹腔内に進入すると右側腹部に大網を覆う巨大腫瘍を確認し、漿液性腹水がみられたが肉眼的に腹膜播種は認められなかった。腹水を採取すると悪性細胞は検出されず、転移が疑われるリンパ節の腫大を同定、巨大腫瘍は炎症性変化をきたして腹膜に癒着しており、超音波デバイスを用いて慎重に切離した。続いてリンパ節4Dと6を大網と右胃大網動脈から切離し、リンパ節202は回結腸動静脈を結紮後に切除した。さらに、回腸末端近位部に沿って回腸を15cmにわたって切離し、巨大腫瘍と横行結腸に対する摘出術を施行した。手術時間は5時間47分、出血量は20mLであった。術後の病理所見、免疫組織化学染色の結果から11q異常を伴うBurkitt様リンパ腫と確定診断を下した。術後経過は良好で、4日目に経口摂取を開始し、腫瘍融解症候群の症状なく寛解が得られている。

  • Yano Keisuke, Muto Mitsuru, Nagai Taichiro, Harumatsu Toshio, Kedoin Chihiro, Nagano Ayaka, Matsui Mayu, Murakami Masakazu, Sugita Koshiro, Onishi Shun, Yamada Koji, Yamada Waka, Matsukubo Makoto, Kaji Tatsuru, Ieiri Satoshi .  小児の腹腔鏡下虫垂切除術におけるアセトアミノフェン静注の鎮痛効果 予定投与とオンデマンド投与の比較(The analgesic effect of the intravenous administration of acetaminophen for pediatric laparoscopic appendectomy: A comparison of scheduled and on-demand procedures) .  Asian Journal of Endoscopic Surgery15 ( 4 ) 715 - 721   2022.10小児の腹腔鏡下虫垂切除術におけるアセトアミノフェン静注の鎮痛効果 予定投与とオンデマンド投与の比較(The analgesic effect of the intravenous administration of acetaminophen for pediatric laparoscopic appendectomy: A comparison of scheduled and on-demand procedures)

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    小児の腹腔鏡下虫垂切除術にみられる術後痛に対するアセトアミノフェン静注の予定投与とオンデマンド投与の有効性を比較検討した。腹腔鏡下虫垂切除術を施行された小児患者94例を静注アセトアミノフェン予定投与群(SA群)42例(平均9.31±2.31歳)とオンデマンド投与群(ODA群)52例(平均9.21±2.89歳)に分類し、両群の患者背景、手術成績、術後アウトカムを比較した。体重、白血球数、CRP、AST値、ALT値、虫垂サイズに関してSA群とODA群との間に有意差はなかった。手術時間、気腹時間、癒着の有無、病理学的診断、術後摂食開始までの期間、抗生剤投与、術後在院期間にも有意な群間差はなく、術後合併症の発症はみられなかった。術後痛に関して、術翌日、2日後ともに疼痛の訴えはSA群の方がODA群より有意に少なく、蜂巣炎性虫垂炎、壊疽性虫垂炎のいずれでも術翌日はSA群の方が疼痛を訴える患児は少なかった。このほか、静注アセトアミノフェンの投与量はSA群の方が有意に多く、救済鎮痛薬としてのペンタゾシンの投与回数に有意な群間差はなかった。小児の腹腔鏡下虫垂切除術後の疼痛に対して、静注アセトアミノフェンの予定投与は有用であることが示された。

  • Murakami M., Muto M., Nakagawa S., Kedoin C., Matsui M., Sugita K., Yano K., Onishi S., Harumatsu T., Yamada K., Yamada W., Matsukubo M., Kawano T., Kodama Y., Nishikawa T., Kaji T., Okamoto Y., Ieiri S. .  Successful laparoscopy-assisted en bloc resection of bulky omental malignant lymphoma involving the ascending colon and multiple lymph node metastases: Report of a technically demanding case in a pediatric patient .  Asian Journal of Endoscopic Surgery15 ( 4 ) 836 - 840   2022.10

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    Language:Japanese   Publisher:Asian Journal of Endoscopic Surgery  

    We herein report a 13-year-old boy with a chief complaint of abdominal pain and a palpable mass. Contrast-enhanced computed tomography (CT) scan showed an abdominal bulky tumor involving the ascending colon causing severe stenosis, with multiple abdominal lymph node metastases detected by positron emission tomography (PET)-CT. Laparoscopic radical resection with right hemicolectomy and lymph node dissection was planned. The bulky tumor was dissected from the retroperitoneum and resected en bloc with the right-side colon and omentum. The preoperatively detected metastatic lymph nodes were resected along with the tumor. A 6-cm longitudinal umbilical incision was made, and the huge tumor was removed, with functional end-to-end anastomosis performed for intestinal reconstruction. The pathological diagnosis was Burkitt-like lymphoma with 11q aberration. The postoperative course was uneventful. Laparoscopy-assisted extirpation is feasible for pediatric solid tumors involving other organs, but indications and procedures should be carefully determined based on preoperative imaging, intraoperative findings and surgeon's skills.

    DOI: 10.1111/ases.13081

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  • Onishi S., Muto M., Yamada K., Murakami M., Kedoin C., Nagano A., Matsui M., Sugita K., Yano K., Harumatsu T., Yamada W., Masuya R., Kawano T., Ieiri S. .  Feasibility of delayed anastomosis for long gap esophageal atresia in the neonatal period using internal traction and indocyanine green-guided near-infrared fluorescence .  Asian Journal of Endoscopic Surgery15 ( 4 ) 877 - 881   2022.10

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    Language:Japanese   Publisher:Asian Journal of Endoscopic Surgery  

    Introduction: Management of neonates with long gap esophageal atresia (LGEA) is one of the most challenging situations facing pediatric surgeons. Delayed anastomosis after internal traction for esophageal lengthening was reported as a useful technique for long gap cases. Additionally, the use of near-infrared (NIR) fluorescence imaging with indocyanine green (ICG) has gained popularity in pediatric surgery, especially for blood perfusion validation. We report a novel technique for safe and secure anastomosis for LGEA in the neonatal period using internal traction and ICG-guided NIR fluorescence. Patient and Surgical Technique: A pregnant woman with polyhydramnios was admitted to the department of obstetrics in our hospital. At 29 weeks of gestation, ultrasound showed mild polyhydramnios and absence of the fetal stomach. A male neonate was born at 38 weeks of gestation with 21 trisomy. EA (Gross type A) was diagnosed based on an X-ray study that showed the absence of gastric bubble with a nasogastric tube showing the “coil-up” sign. Thoracoscopic internal traction and laparoscopic gastrostomy were performed on day 4 after birth. We confirmed the distance between the upper pouch and lower pouch on X-ray. On day 16 after birth, thoracoscopic anastomosis was performed. We successfully performed esophageal anastomosis without tearing the esophageal wall. Blood perfusion of the upper and lower pouch was validated after anastomosis using ICG-guided NIR fluorescence. Conclusion: Delayed anastomosis for LGEA in the neonatal period using internal traction and ICG-guided NIR fluorescence is safe and feasible.

    DOI: 10.1111/ases.13098

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  • Onishi S., Muto M., Harumatsu T., Murakami M., Kedoin C., Matsui M., Sugita K., Yano K., Yamada K., Yamada W., Matsukubo M., Kaji T., Ieiri S. .  Intraoperative visualization of urethra using illuminating catheter in laparoscopy-assisted anorectoplasty for imperforated anus—A novel and safe technique for preventing urethral injury .  Asian Journal of Endoscopic Surgery15 ( 4 ) 867 - 871   2022.10

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    Purpose: In this study, we used a near-infrared ray catheter (NIRC) to visualize the urethral line. We herein report our intraoperative visualization technique of the urethra using an illuminating catheter in laparoscopy-assisted anorectoplasty (LAARP) for imperforated anus. Patient and surgical technique: A 3.0-kg term male neonate with anorectal malformation was delivered. An invertogram revealed the type as intermediate. Transverse colostomy was performed at the left upper abdomen. A recto-bulbar urethral fistula (RBUF) was diagnosed via distal colostogram and voiding cystourethrogram. LAARP was planned at 6 months of age. We performed the operation with four trocars. A 45° 5-mm scope was used to clearly view the deep pelvic space. Before starting rectal dissection, a 6-Fr pig-tail-type NIRC was inserted through the external opening of the urethra to visualize the urethra during the laparoscopic procedure. The catheter tip was placed in the bladder, and excretion of urine was maintained through the NIRC during the procedures. While dissecting the deep pelvic space between the posterior wall of the urethra and anterior wall of the rectum, the exact line of the urethra was clearly confirmed by overlay images of the NIRC. The RBUF was dissected safely using this innovative image-guided technique. Anoplasty was performed between the rectal stump and perineal skin. The postoperative course was uneventful. Oral intake was started on postoperative day 1. Postoperative dynamic urography showed no complications. Conclusion: An NIRC is useful for detecting the urethra during LAARP.

    DOI: 10.1111/ases.13061

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  • Yano K, Sugita K, Yamada K, Matsui M, Yamada W, Kedoin C, Murakami M, Harumatsu T, Onishi S, Kawano T, Muto M, Ieiri S .  Successful laparoscopic repair for reduction en masse of infantile inguinal hernia: a case report of this rare condition. .  Surgical case reports8 ( 1 ) 181   2022.9Successful laparoscopic repair for reduction en masse of infantile inguinal hernia: a case report of this rare condition.

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    DOI: 10.1186/s40792-022-01535-1

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  • Yano Keisuke, Sugita Koshiro, Yamada Koji, Matsui Mayu, Yamada Waka, Kedoin Chihiro, Murakami Masakazu, Harumatsu Toshio, Onishi Shun, Kawano Takafumi, Muto Mitsuru, Ieiri Satoshi .  Successful laparoscopic repair for reduction en masse of infantile inguinal hernia: a case report of this rare condition(タイトル和訳中) .  Surgical Case Reports8   1 of 5 - 5 of 5   2022.9Successful laparoscopic repair for reduction en masse of infantile inguinal hernia: a case report of this rare condition(タイトル和訳中)

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  • Muto M., Sugita K., Matsuba T., Kedoin C., Matsui M., Ikoma S., Murakami M., Yano K., Onishi S., Harumatsu T., Yamada K., Yamada W., Matsukubo M., Kawano T., Machigashira S., Torikai M., Kaji T., Ibara S., Imoto Y., Soga Y., Ieiri S. .  How should we treat representative neonatal surgical diseases with congenital heart disease? .  Pediatric Surgery International38 ( 9 ) 1235 - 1240   2022.9

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    Purpose: Representative neonatal surgical diseases are often complicated by congenital heart disease (CHD). We reviewed our decade of experience from the perspective of the prognosis and report on the management of infants with CHD. Methods: Cases with and without CHD between 2011 and 2020 were retrospectively compared. Qualitative data were analyzed using a chi-square test with Yates' correction, and quantitative data were compared using Student's t-test. Results: Of the 275 neonatal surgical cases, 36 had CHD (13.1%). Ventricular septal defect was the most common cardiac anomaly, followed by atrial septal defect. Esophageal atresia showed the highest complication rate of CHD (43.8%, 14/32) followed by duodenal atresia (38.5%, 10/26). The mortality rates of patients with and without CHD (22.2% [8/36] vs. 1.3% [3/239]) were significantly different (χ2 = 30.6, p < 0.0001). Of the eight deaths with CHD, six patients had cyanotic complex CHD. Notably, four of these patients died from progression of inappropriate hemodynamics in the remote period after definitive non-cardiac surgery. Conclusion: Considering its high-mortality, the presence of CHD, especially cyanotic heart disease, is an important issue to consider in the treatment of neonatal surgical diseases. Pediatric surgeons should be alert for changes in hemodynamics after surgery, as these may affect mortality.

    DOI: 10.1007/s00383-022-05178-z

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  • Yano K., Sugita K., Muto M., Matsukubo M., Onishi S., Kedoin C., Matsui M., Murakami M., Harumatsu T., Yamada K., Yamada W., Kumagai K., Ido A., Kaji T., Ieiri S. .  The preventive effect of recombinant human hepatocyte growth factor for hepatic steatosis in a rat model of short bowel syndrome .  Journal of Pediatric Surgery57 ( 7 ) 1286 - 1292   2022.7

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    Purpose: Short bowel syndrome (SBS) patients require total parenteral nutrition (TPN) following massive small bowel resection (SBR), which may cause intestinal failure-associated liver disease (IFALD), a life-threatening complication. Hepatocyte growth factor (HGF) acts as a potent hepatocyte mitogen with anti inflammatory and antioxidant actions. The present study evaluated the effect of recombinant human HGF (rh-HGF) on SBR and subsequent IFALD using a parentally fed rat model of SBS. Methods: Rats underwent jugular vein catheterization for continuous TPN and 90% SBR. They were divided into 2 groups: TPN alone (SBS/TPN group: n = 7) or TPN plus the intravenous administration of rh-HGF (0.3 mg/kg/day) (SBS/TPN+HGF group: n = 7). On day 7, their tissues and stool were harvested to evaluate the effects of HGF. Results: Regarding the histological findings, based on the nonalcoholic fatty liver disease (NAFLD) activity score, the SBS/TPN+HGF group showed significantly less hepatic steatosis and inflammatory cell infiltration than the SBS/TPN group (NAFLD activity score, 4.00 ± 1.83 vs. 1.00 ± 0.82; p < 0.01). The SBS/TPN+HGF group showed a higher expression of Farnesoid X receptor in the liver and lower expression of Toll-like receptor 4 in the ileum than the SBS/TPN group. Regarding the composition of the bacterial gut microbiota, Actinobacteria, Bacteroidetes and Proteobacteria were decreased in the SBS/TPN+HGF group compared with the SBS/TPN group. Conclusion: In our SBS with TPN rat model, rh-HGF administration had a preventive effect against hepatic steatosis and dysbiosis. rh-HGF may therefore be a potentially effective therapeutic agent for SBS and subsequent IFALD. Type of study: Experimental research.

    DOI: 10.1016/j.jpedsurg.2022.02.030

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  • Muto M., Onishi S., Murakami M., Kedoin C., Yano K., Harumatsu T., Yamada K., Yamada W., Kaji T., Ieiri S. .  Useful traction technique for laparoscopic fundoplication without removing proceeding gastrostomy in a neurologically impaired patient with a body deformity .  Asian Journal of Endoscopic Surgery15 ( 3 ) 697 - 699   2022.7

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    Severely neurologically impaired patients often require the creation of a gastrostomy when they develop difficulty with oral intake followed by antireflux surgery. We use a traction technique for laparoscopic fundoplication without removing the gastrostomy in such cases. Right lateral traction of the round ligament of the liver and left lateral traction of the stomach body are performed using a needle device. The left liver lobe is elevated with a liver retractor inserted via the epigastrium. This traction technique allows a sufficient surgical field for manipulating forceps to be created in cases with a gastrostomy, enabling fundoplication to be performed safely without removing the gastrostomy.

    DOI: 10.1111/ases.13028

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  • Muto Mitsuru, Onishi Shun, Murakami Masakazu, Kedoin Chihiro, Yano Keisuke, Harumatsu Toshio, Yamada Koji, Yamada Waka, Kaji Tatsuru, Ieiri Satoshi .  奇形を有する神経障害患者への胃瘻抜去を伴わない腹腔鏡下噴門形成術における有用な牽引法(Useful traction technique for laparoscopic fundoplication without removing proceeding gastrostomy in a neurologically impaired patient with a body deformity) .  Asian Journal of Endoscopic Surgery15 ( 3 ) 697 - 699   2022.7奇形を有する神経障害患者への胃瘻抜去を伴わない腹腔鏡下噴門形成術における有用な牽引法(Useful traction technique for laparoscopic fundoplication without removing proceeding gastrostomy in a neurologically impaired patient with a body deformity)

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    症例は42歳男性で、低酸素性脳症を原因とする脳性麻痺を呈しており、経口摂取が困難で腹腔鏡下胃瘻造設術を受けていた。胃食道逆流のために頻回な誤嚥性肺炎をきたし、腹腔鏡下噴門形成術を行った。四肢拘縮と側彎を考慮して斜仰臥位にて右尾側から手術を開始した。臍切開部より12mm Hassonトロカーを挿入し、気腹を8mmHgに設定した後に腹腔鏡を挿入、左手ポート(5mm)を右上腹部より挿入しニードルデバイスを用いて肝円索を2-0絹糸により右側方に牽引し、さらに胃体部を3-0モノフィラメント縫合糸を用いて左側方に牽引した。続いて、右手ポート(5mm)を胃瘻部に近接する左上腹部に挿入し、補助ポート(5mm)を左側方冠側の胃瘻近接部に留置、肝開創器を心窩部を介して挿入し肝左葉を挙上した。さらに横隔膜脚部を同定し腹部食道を露出後、脚部を縫合処理し、3-0ポリエステル非吸収性縫合糸を用いて被覆固定を行い、被覆した胃底中部と横隔膜右脚部を固定処理して手術を終了した。

  • Kedoin Chihiro, Harumatsu Toshio, Yano Keisuke, Nagano Ayaka, Matsui Mayu, Murakami Masakazu, Sugita Koshiro, Muto Mitsuru, Kaji Tatsuru, Ieiri Satoshi .  Effectiveness of Laparoscopic External Drainage of Pancreatic Pseudocyst After Traumatic Main Pancreatic Duct Disruption: A Case Report .  Journal of the Japanese Society of Pediatric Surgeons58 ( 4 ) 734 - 739   2022.6

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    Language:Japanese   Publisher:The Japanese Society of Pediatric Surgeons  

    <p>We successfully treated a case of pancreatic pseudocyst caused by type IIIb pancreatic injury via laparoscopic external drainage. [Case] A 14-year-old boy presented with abdominal pain after having his upper abdomen bruised by contact with another player’s knee during a soccer match. Magnetic resonance cholangiopancreatography (MRCP) showed complete rupture of the pancreatic body, and fluid collection was detected around it. The patient was diagnosed as having type IIIb pancreatic injury based on the classification of the Japanese Society of Trauma. We selected a non-operative management approach because the patient was hemodynamically stable. However, after conservative treatment, a pancreatic pseudocyst of 3 cm diameter was found; thus, endoscopic retrograde pancreatography (ERP) was performed on the 11th day of illness. The pancreatic duct was transected at the body of the pancreas, and a pancreatic duct stent was placed into the cyst, but it fell off after three days. After that, the pancreatic pseudocyst tended to grow and increased in size from the subdiaphragm to the lower pole of the kidney. Therefore, we performed laparoscopic external drainage on the 45th day of hospitalization. After the operation, the patient showed no abdominal symptoms, and no recurrence of cysts was recognized. [Conclusion] Laparoscopic drainage of pancreatic pseudocysts can enable the observation of the entire abdominal cavity while also facilitating safe and reliable drainage. Therefore, depending on the patient condition, laparoscopic external drainage of pancreatic pseudocysts may be considered as a treatment option.</p>

    DOI: 10.11164/jjsps.58.4_734

  • 祁答院 千寛, 春松 敏夫, 矢野 圭輔, 長野 綾香, 松井 まゆ, 村上 雅一, 杉田 光士郎, 武藤 充, 加治 建, 家入 里志 .  外傷性膵損傷後の膵仮性嚢胞に対し腹腔鏡下嚢胞開窓ドレナージが奏功した1例 .  日本小児外科学会雑誌58 ( 4 ) 734 - 739   2022.6外傷性膵損傷後の膵仮性嚢胞に対し腹腔鏡下嚢胞開窓ドレナージが奏功した1例

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    今回、IIIb型膵損傷後の膵仮性嚢胞に対し、腹腔鏡下嚢胞ドレナージが奏功した1例を経験した。【症例】症例は14歳男児。サッカーの試合中に他選手の膝で上腹部を打撲後に腹痛を訴え救急搬送された。Magnetic resonance cholangiopancreatography(MRCP)では日本外傷学会分類IIIb型の膵損傷と診断した。全身状態は安定しており保存的に加療する方針とした。しかしその後に、3cm大の膵仮性嚢胞を認め、内視鏡的逆行性膵管造影を11病日に施行した。主膵管は膵体部で断裂し、膵管ステントを嚢胞内へ留置したが数日で脱落した。その後、嚢胞は横隔膜下から腎下極に及ぶまで増大したため、入院45日目に腹腔鏡下嚢胞開窓ドレナージ術を行った。術後は腹部症状や嚢胞の再発は認めず経過している。【結語】膵仮性嚢胞に対する腹腔鏡下嚢胞ドレナージは、腹腔内の観察ができ、確実なドレナージが可能である。病態に応じて膵仮性嚢胞のドレナージ法の選択肢として検討されうると考えられた。(著者抄録)

  • 村上 雅一, 祁答院 千寛, 杉田 光士郎, 長野 綾香, 松井 まゆ, 西田 ななこ, 矢野 圭輔, 春松 敏夫, 大西 峻, 山田 耕嗣, 山田 和歌, 松久保 眞, 武藤 充, 家入 里志 .  特集 小児の便秘:最近の知見 重症心身障碍児と便秘症 .  小児外科54 ( 4 ) 376 - 380   2022.4

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    Publisher:東京医学社  

    DOI: 10.24479/ps.0000000100

  • 村上 雅一, 祁答院 千寛, 杉田 光士郎, 長野 綾香, 松井 まゆ, 西田 ななこ, 矢野 圭輔, 春松 敏夫, 大西 峻, 山田 耕嗣, 山田 和歌, 松久保 眞, 武藤 充, 家入 里志 .  【小児の便秘:最近の知見】重症心身障碍児と便秘症 .  小児外科54 ( 4 ) 376 - 380   2022.4【小児の便秘:最近の知見】重症心身障碍児と便秘症

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    過去5年間に当施設で入院診療を行った重症心身障碍児82人(男性56人、女性26人、平均年齢19.8歳)を対象として、便秘や呑気などの臨床症状と、処方されていた薬を後方視的に分析した。手術は95件行われており、噴門形成術、胃瘻造設術、気管切開術などの予定手術が81件、イレウス解除術などの緊急手術が14件であった。術前の栄養形態は半消化態栄養剤が67人で最も多く、成分栄養剤7人、消化態栄養剤1人、ミルク6人で経口摂取は1人のみであった。術前薬については漢方製剤を20人、刺激性下剤を20人、整腸剤を19人、塩類下剤を15人、浸透圧下剤を1人が使用していた。浣腸のみを含めて無投薬は33人であった。術前の腹部単純X線で宿便を認めたのは5人のみであったが、広範な小腸ガス貯留など呑気による影響と考えられる所見は44人で認められた。呑気症を背景にイレウスを繰り返した2症例を提示した。

  • Sugita Koshiro, Onishi Shun, Kedoin Chihiro, Matsui Mayu, Murakami Masakazu, Yano Keisuke, Harumatsu Toshio, Yamada Koji, Yamada Waka, Matsukubo Makoto, Muto Mitsuru, Kaji Tatsuru, Ieiri Satoshi .  インドシアニングリーンを用いた蛍光画像により腸間膜灌流を確認した腹腔鏡下Ladd法の安全性と有効性 新生児の1症例報告(A safe and effective laparoscopic Ladd's procedure technique involving the confirmation of mesenteric vascular perfusion by fluorescence imaging using indocyanine green: A case report of an infant) .  Asian Journal of Endoscopic Surgery15 ( 2 ) 410 - 414   2022.4インドシアニングリーンを用いた蛍光画像により腸間膜灌流を確認した腹腔鏡下Ladd法の安全性と有効性 新生児の1症例報告(A safe and effective laparoscopic Ladd's procedure technique involving the confirmation of mesenteric vascular perfusion by fluorescence imaging using indocyanine green: A case report of an infant)

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    症例は1歳8ヵ月の男児で、生後一時的に胆汁嘔吐をきたしたが症状は自然消失し、発達障害はみられなかった。1歳4ヵ月時、間欠的な胆汁嘔吐を認め、精査目的に当院を受診した。上部消化管造影検査で十二指腸球部から下部にかけての拡張がみられ、下部から水平部にかけての造影剤のうっ滞が生じていた。造影CTでは上腸間膜動脈と上腸間膜静脈(SMV)の配置に異常はみられなかったが、末梢部にてコークスクリュー徴候を認め、SMVの著明な狭窄と側副循環が検出された。以上の所見から中腸軸捻を伴う腸回転異常と診断し、腹腔鏡下手術を計画した。中腸軸捻を回盲部からの小腸トレースにより逆行性に解除し腸間膜根部を確認、腸間膜に重度の癒着が生じていたため、インドシアニングリーンによる蛍光ナビゲーション下に組織をクランプして灌流を図った。これにより安全な組織の切離が可能となり、腸間膜根部の開大を確認できた。腸管を非回転位に収納し脾彎曲部の結腸はBill法を用いて固定した。術後2日目に飲水、3日目に摂食が可能となり、5日目に退院となった。その後4ヵ月、軸捻やイレウスの再発は認めていない。

  • Sugita K., Onishi S., Kedoin C., Matsui M., Murakami M., Yano K., Harumatsu T., Yamada K., Yamada W., Matsukubo M., Muto M., Kaji T., Ieiri S. .  A safe and effective laparoscopic Ladd's procedure technique involving the confirmation of mesenteric vascular perfusion by fluorescence imaging using indocyanine green: A case report of an infant .  Asian Journal of Endoscopic Surgery15 ( 2 ) 410 - 414   2022.4

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    We herein report a 20-month-old boy who underwent laparoscopic Ladd's surgery. He showed intermittent bilious vomiting after birth and received a definitive diagnosis of intestinal malrotation. Laparoscopic Ladd's procedure was performed with four trocars. Midgut volvulus (180° counterclockwise) was resolved by retrogradely tracing the small intestine from the ileocecal region. After dividing Ladd's ligament, fluorescent navigation with indocyanine green was used. We decided where to dissect the mesenteries by confirming the vascular perfusion through clamping the tissue. Fibrous adhesions were gradually dissected, and it was confirmed that the mesenteric root was sufficiently broadening. Surgeons hesitate to dissect the mesenteric root in laparoscopic procedures compared with open procedures because of the narrow operative view and the risk of vascular injury. Laparoscopic Ladd's procedure using indocyanine green to confirm intestinal blood flow is safe and useful for the small working space in pediatric patients with intestinal malrotation and midgut volvulus.

    DOI: 10.1111/ases.13026

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  • Matsukubo M, Muto M, Kedoin C, Matsui M, Murakami M, Sugita K, Yano K, Onishi S, Harumatsu T, Yamada K, Yamada W, Kaji T, Ieiri S .  An unusual presentation of intestinal duplication mimicking torsion of Meckel's diverticulum: a rare report of a pediatric case. .  Surgical case reports8 ( 1 ) 53   2022.3An unusual presentation of intestinal duplication mimicking torsion of Meckel's diverticulum: a rare report of a pediatric case.

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    DOI: 10.1186/s40792-022-01409-6

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  • Matsukubo Makoto, Muto Mitsuru, Kedoin Chihiro, Matsui Mayu, Murakami Masakazu, Sugita Koshiro, Yano Keisuke, Onishi Shun, Harumatsu Toshio, Yamada Koji, Yamada Waka, Kaji Tatsuru, Ieiri Satoshi .  メッケル憩室捻転を呈した非典型的な消化管重複症 小児の稀な1症例報告(An unusual presentation of intestinal duplication mimicking torsion of Meckel's diverticulum: a rare report of a pediatric case) .  Surgical Case Reports8   1 of 6 - 6 of 6   2022.3メッケル憩室捻転を呈した非典型的な消化管重複症 小児の稀な1症例報告(An unusual presentation of intestinal duplication mimicking torsion of Meckel's diverticulum: a rare report of a pediatric case)

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    Language:English   Publisher:Springer Berlin Heidelberg  

    症例は3歳男児で、突然の腹痛を主訴に近医を受診した。ウイルス性胃腸炎と診断され、保存的治療が行われたが症状は改善しなかった。X線検査で腸管拡張とイレウスを認め、当院へ搬送された。腹部膨隆と腹部全体に圧痛を認め、特に下腹部で強い筋性防御(腹膜刺激徴候)を認めた。臨床検査で白血球数は20800/μL、C反応性蛋白質は5.79mg/dLの高値を呈した。ASTは29U/L、ALTは11U/L、総ビリルビンは0.8mg/dL、尿素窒素は8.0mg/dL、クレアチニンは0.21mg/dLであった。造影CTで構造が消化管に似た嚢胞性病変と腹水を認めた。腸管拡張またはイレウスの所見は見られなかった。消化管への血流は保持されていたため、メッケル憩室捻転の疑いで診断的腹腔鏡検査を実施した。右下腹部に黒色の管状構造を形成する嚢胞性病変が720°茎捻転していた。捻転を整復したところ、メッケル憩室捻転ではなく、消化管重複症であった。重複腸管を切除した。病理組織学的検査で切除標本は回腸壁の構成要素を有していた。術後経過は良好で、14日後に退院となった。3年後の再診で合併症は見られなかった。

  • Kawano Takafumi, Sugita Koshiro, Kedoin Chihiro, Nagano Ayaka, Matsui Mayu, Murakami Masakazu, Kawano Masato, Yano Keisuke, Onishi Shun, Harumatsu Toshio, Yamada Koji, Yamada Waka, Masuya Ryuta, Matsukubo Makoto, Muto Mitsuru, Machigashira Seiro, Nakame Kazuhiko, Mukai Motoi, Kaji Tatsuru, Ieiri Satoshi .  小児の後腹膜奇形腫 単施設の経験(Retroperitoneal teratomas in children: a single institution experience) .  Surgery Today52 ( 1 ) 144 - 150   2022.1小児の後腹膜奇形腫 単施設の経験(Retroperitoneal teratomas in children: a single institution experience)

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    単施設において、1984年4月~2017年12月に後腹膜奇形腫(RPT)の治療を行った小児患者15例(男児4例、女児11例)の治療経験を報告した。年齢は日齢6~12歳であり、15例中11例(73.3%)が1歳未満であった。すべての患者で外科的完全切除術が施行された。術中の腫瘍破裂を4例(26.7%)に、周術期の血管損傷を6例(40.0%)に認め、最終的には1例(6.7%)が腎摘出術を要した。また、手術合併症として、片側腎機能障害を3例(20.0%)に認めた。術後化学療法を施行した患者は1例のみであった。その後いずれの患者も治癒している。

  • Kawano T., Sugita K., Kedoin C., Nagano A., Matsui M., Murakami M., Kawano M., Yano K., Onishi S., Harumatsu T., Yamada K., Yamada W., Masuya R., Matsukubo M., Muto M., Machigashira S., Nakame K., Mukai M., Kaji T., Ieiri S. .  Retroperitoneal teratomas in children: a single institution experience .  Surgery Today52 ( 1 ) 144 - 150   2022.1

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    Purpose: Retroperitoneal teratomas (RPTs) are rare in infants. We report our experience of treating pediatric patients with RPTs over many years at a single institution, with the aim of developing a safe and secure operative strategy for RPTs in infants. Methods: We reviewed the medical records of patients who underwent treatment for RPTs in our institution between April, 1984 and December, 2017, to analyze their background and clinical data. The diagnosis of RPT was confirmed histologically in all patients. Results: The subjects of this retrospective analysis were 14 pediatric patients (female, n = 11; male, n = 4), ranging in age from 6 days to 12 years, 11 (73.3%) of whom were under 1 year of age. Complete surgical resection was performed in all patients. The tumor ruptured during surgery in four (26.7%) patients and perioperative vessel injuries occurred in six (40.0%) patients, resulting in nephrectomy in one (6.7%). Three (20.0%) patients suffered unilateral renal dysfunction as a surgical complication. Only one patient received postoperative chemotherapy. All patients were free of disease at the time of writing. Conclusion: Perioperative complications are not uncommon during surgery for RPTs, despite their benign nature. Preoperative imaging evaluation is important and operative management may be challenging. Because of the favorable prognosis and the frequency of adverse events in surgery, partial resection or split excision is sometimes unavoidable. Meticulous follow-up for recurrence is required for such patients.

    DOI: 10.1007/s00595-021-02327-0

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    PubMed

  • Onishi S, Yamada K, Murakami M, Kedoin C, Muto M, Ieiri S .  Co-injection of Bile and Indocyanine Green for Detecting Pancreaticobiliary Maljunction of Choledochal Cyst. .  European journal of pediatric surgery reports10 ( 1 ) e127 - e130   2022.1Co-injection of Bile and Indocyanine Green for Detecting Pancreaticobiliary Maljunction of Choledochal Cyst.

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    DOI: 10.1055/s-0042-1747913

    PubMed

  • 大西 峻, 川野 孝文, 祁答院 千寛, 松井 まゆ, 村上 雅一, 矢野 圭輔, 杉田 光士郎, 春松 敏夫, 山田 耕嗣, 山田 和歌, 松久保 眞, 武藤 充, 加治 建, 家入 里志 .  特集 小児外科疾患の家族内発生 Hirschsprung病 .  小児外科53 ( 12 ) 1281 - 1284   2021.12

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    Publisher:(株)東京医学社  

    DOI: 10.24479/j00645.2022081276

  • Onishi S, Kedoin C, Murakami M, Higa N, Yoshida A, Onitsuka K, Moriyama T, Yoshimoto K, Ieiri S .  Image-guided confirmation of a precision pull-through procedure during laparoscopically assisted anorectoplasty in an open MRI operating theater: first application in an infantile case with anorectal malformation. .  Surgical case reports7 ( 1 ) 211   2021.9Image-guided confirmation of a precision pull-through procedure during laparoscopically assisted anorectoplasty in an open MRI operating theater: first application in an infantile case with anorectal malformation.

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    DOI: 10.1186/s40792-021-01298-1

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  • Onishi Shun, Kedoin Chihiro, Murakami Masakazu, Higa Hayuta, Yoshida Akihiro, Onitsuka Kazutoshi, Moriyama Takahiro, Yoshimoto Koji, Ieiri Satoshi .  オープンMRI手術室における腹腔鏡下肛門直腸形成術中の画像ガイド下pull-through法:肛門直腸奇形を呈する乳児例への初めての適用(Image-guided confirmation of a precision pull-through procedure during laparoscopically assisted anorectoplasty in an open MRI operating theater: first application in an infantile case with anorectal malformation) .  Surgical Case Reports7   1 of 6 - 6 of 6   2021.9オープンMRI手術室における腹腔鏡下肛門直腸形成術中の画像ガイド下pull-through法:肛門直腸奇形を呈する乳児例への初めての適用(Image-guided confirmation of a precision pull-through procedure during laparoscopically assisted anorectoplasty in an open MRI operating theater: first application in an infantile case with anorectal malformation)

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    症例は正期産で出生した男児で、肛門直腸奇形を認めた。Invertogramでは中間型であり、左上腹部に横行結腸瘻を造設し、直腸球部尿道瘻(RBUF)と診断、6ヵ月時にオープンMRIによる腹腔鏡下肛門直腸形成術を行った。手術の3週前にオープンMRIシステムを用いて骨盤底を撮像し、直腸pull-through法が施行可能であると判断した。全身麻酔下に手術を開始し、臍部に縦切開を置きトロカーを挿入、気腹を確立後に右上腹部、右下腹部および臍部左側にトロカーを追加した。骨盤神経損傷を回避する目的で直腸切離を行い、その後に縫合糸を用いてRBUFを閉鎖し、ステープラーで切離後に結紮を施した。肛門形成後にオープンMRIスキャンを実施し、pull-throughされた直腸が筋複合体中心に位置することを確認した。手術時間は420分、撮像時間は40分であった。術後経過は良好で術翌日に経口摂取が可能となり、14日目のダイナミック尿路造影では合併症はなく、15日目に退院となった。3ヵ月後、結腸造影を施行して横行結腸瘻を解除する予定である。

  • Nagano A, Onishi S, Kedoin C, Matsui M, Murakami M, Sugita K, Yano K, Harumatsu T, Yamada K, Yamada W, Matsukubo M, Muto M, Kaji T, Ieiri S .  A rare case of accessory liver lobe torsion in a pediatric patient who showed recurrent epigastralgia and who was treated by elective laparoscopic resection. .  Surgical case reports7 ( 1 ) 143   2021.6A rare case of accessory liver lobe torsion in a pediatric patient who showed recurrent epigastralgia and who was treated by elective laparoscopic resection.

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    DOI: 10.1186/s40792-021-01231-6

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  • Nagano Ayaka, Onishi Shun, Kedoin Chihiro, Matsui Mayu, Murakami Masakazu, Sugita Koshiro, Yano Keisuke, Harumatsu Toshio, Yamada Koji, Yamada Waka, Matsukubo Makoto, Muto Mitsuru, Kaji Tatsuru, Ieiri Satoshi .  反復性心窩部痛を認め待機的腹腔鏡下切除術で治療した副肝葉捻転患児の稀な1症例(A rare case of accessory liver lobe torsion in a pediatric patient who showed recurrent epigastralgia and who was treated by elective laparoscopic resection) .  Surgical Case Reports7   1 of 5 - 5 of 5   2021.6反復性心窩部痛を認め待機的腹腔鏡下切除術で治療した副肝葉捻転患児の稀な1症例(A rare case of accessory liver lobe torsion in a pediatric patient who showed recurrent epigastralgia and who was treated by elective laparoscopic resection)

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    3ヵ月前から心窩部痛と嘔吐が2週毎に発生していた5歳女児症例について検討した。腹部超音波検査では肝円索付近に非血管病変が判明した。造影CTでは肝円索の右側にhyperdense lineとdisproportionate fat strandingに囲まれたlow attenuation massを認めた。腹水や出血はなく、肝円索膿瘍が示唆された。経口抗生物質投与で症状は改善し、待機的探索的腹腔鏡検査および切除術を計画した。マルチチャネルポートデバイスから臍に二つの5mmトロカール、右脇腹に一つの3mmトロカールを挿入した。腹腔の観察では肝円索に網が癒着しており、肉眼的観察では明らかな腫瘤病変は認めなかった。肝円索からの網癒着剥離術を行い、癒着形成部位を切除し、切除検体を臍創から摘出した。術後の経過は良好であった。病理学的所見では壊死性肝組織が判明し、切除組織は虚血性変化を伴った副肝葉であった。

  • 山田 耕嗣, 祁答院 千寛, 長野 綾香, 松井 まゆ, 村上 雅一, 矢野 圭輔, 杉田 光士郎, 大西 峻, 春松 敏夫, 山田 和歌, 松久保 眞, 武藤 充, 加治 建, 家入 里志 .  特集 シミュレーションとナビゲーション 腹腔鏡手術トレーニングシミュレータ .  小児外科53 ( 5 ) 499 - 503   2021.5

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    DOI: 10.24479/j00645.2021229964

  • 大西 峻, 山田 耕嗣, 祁答院 千寛, 松井 まゆ, 長野 綾香, 村上 雅一, 矢野 圭輔, 杉田 光士郎, 春松 敏夫, 山田 和歌, 松久保 眞, 武藤 充, 加治 建, 家入 里志 .  特集 シミュレーションとナビゲーション 3Dプリンターを用いた疾患型シミュレータ .  小児外科53 ( 5 ) 494 - 498   2021.5

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    DOI: 10.24479/j00645.2021229963

  • 家入 里志, 大西 峻, 祁答院 千寛, 長野 綾香, 松井 まゆ, 村上 雅一, 杉田 光士郎, 矢野 圭輔, 春松 敏夫, 山田 耕嗣, 山田 和歌, 松久保 眞, 武藤 充, 加治 建 .  特集 小児外科疾患における公費負担医療の種類と申請方法 Hirschsprung病 .  小児外科53 ( 3 ) 303 - 307   2021.3

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    DOI: 10.24479/j00645.2021163596

  • 山田 耕嗣, 祁答院 千寛, 松井 まゆ, 村上 雅一, 矢野 圭輔, 春松 敏夫, 大西 峻, 山田 和歌, 武藤 充, 加治 建, 家入 里志 .  腹腔鏡下肝管空腸吻合術シミュレータの開発 .  日本膵・胆管合流異常研究会プロシーディングス44 ( 0 ) 62 - 63   2021

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    Language:Japanese   Publisher:日本膵・胆管合流異常研究会  

    DOI: 10.34410/jspbm.44.0_62

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  • 【今日の小児肝移植】非移植施設からみた肝移植の課題について 肝小腸異時移植症例の管理経験から

    武藤 充, 大西 峻, 矢野 圭輔, 高田 倫, 岩元 祐実子, 緒方 将人, 祁答院 千寛, 村上 雅一, 杉田 光士郎, 春松 敏夫, 川野 孝文, 大浦 飛鳥, 東小薗 未弥子, 佐々木 文郷, 西川 拓朗, 上村 修司, 家入 里志

    小児外科   55 ( 6 )   684 - 688   2023.6

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  • 【ロボット支援手術】小児外科領域における次世代手術支援ロボット開発 Soft Roboticsの可能性

    家入 里志, 山田 耕嗣, 大西 峻, 村上 雅一, 矢野 圭輔, 岩元 祐実子, 緒方 将人, 高田 倫, 祁答院 千寛, 杉田 光士郎, 春松 敏夫, 山田 和歌, 川野 孝文, 武藤 充

    小児外科   55 ( 5 )   525 - 531   2023.5

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  • 【どうする?小児の便秘・下痢】便秘の原因となる器質的疾患の診断と長期的な治療戦略 Hirschsprung病

    大西 峻, 西田 ななこ, 祁答院 千寛, 長野 綾香, 村上 雅一, 杉田 光士郎, 春松 敏夫, 川野 孝文, 武藤 充, 家入 里志

    小児内科   55 ( 3 )   385 - 389   2023.3

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    <Key Points>(1)H病の術後排便機能は良好とされてきたが,詳細な検索では3割程度の患児に術後の便秘症状がみられる。(2)多くは食事療法,整腸剤,緩下剤,漢方薬,浣腸などでコントロールされるが,重度になると腹部膨満,腸閉塞,腸炎を併発する。(3)幼児期の慢性便秘のなかにもH病患児が隠れていることがあるため,薬剤治療に抵抗性でコントロール不良の症例は,小児外科に紹介のうえ精査を依頼することが望ましい。(著者抄録)

  • 鎖肛に対する腹腔鏡支援肛門直腸形成術における発光カテーテルを用いた術中尿管視覚化 尿管損傷を予防する新規の安全な手技(Intraoperative visualization of urethra using illuminating catheter in laparoscopy-assisted anorectoplasty for imperforated anus-A novel and safe technique for preventing urethral injury)

    Onishi Shun, Muto Mitsuru, Harumatsu Toshio, Murakami Masakazu, Kedoin Chihiro, Matsui Mayu, Sugita Koshiro, Yano Keisuke, Yamada Koji, Yamada Waka, Matsukubo Makoto, Kaji Tatsuru, Ieiri Satoshi

    Asian Journal of Endoscopic Surgery   15 ( 4 )   867 - 871   2022.10

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  • 内牽引とインドシアニングリーンガイド下近赤外蛍光法を用いた新生児期のlong gap食道閉鎖症に対する遅延吻合の実行可能性(Feasibility of delayed anastomosis for long gap esophageal atresia in the neonatal period using internal traction and indocyanine green-guided near-infrared fluorescence)

    Onishi Shun, Muto Mitsuru, Yamada Koji, Murakami Masakazu, Kedoin Chihiro, Nagano Ayaka, Matsui Mayu, Sugita Koshiro, Yano Keisuke, Harumatsu Toshio, Yamada Waka, Masuya Ryuta, Kawano Takafumi, Ieiri Satoshi

    Asian Journal of Endoscopic Surgery   15 ( 4 )   877 - 881   2022.10

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  • 【小児外科疾患の家族内発生】Hirschsprung病

    大西 峻, 川野 孝文, 祁答院 千寛, 松井 まゆ, 村上 雅一, 矢野 圭輔, 杉田 光士郎, 春松 敏夫, 山田 耕嗣, 山田 和歌, 松久保 眞, 武藤 充, 加治 建, 家入 里志

    小児外科   53 ( 12 )   1281 - 1284   2021.12

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  • 【シミュレーションとナビゲーション】腹腔鏡手術トレーニングシミュレータ

    山田 耕嗣, 祁答院 千寛, 長野 綾香, 松井 まゆ, 村上 雅一, 矢野 圭輔, 杉田 光士郎, 大西 峻, 春松 敏夫, 山田 和歌, 松久保 眞, 武藤 充, 加治 建, 家入 里志

    小児外科   53 ( 5 )   499 - 503   2021.5

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  • 【シミュレーションとナビゲーション】3Dプリンターを用いた疾患型シミュレータ

    大西 峻, 山田 耕嗣, 祁答院 千寛, 松井 まゆ, 長野 綾香, 村上 雅一, 矢野 圭輔, 杉田 光士郎, 春松 敏夫, 山田 和歌, 松久保 眞, 武藤 充, 加治 建, 家入 里志

    小児外科   53 ( 5 )   494 - 498   2021.5

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  • 【小児外科疾患における公費負担医療の種類と申請方法】Hirschsprung病

    家入 里志, 大西 峻, 祁答院 千寛, 長野 綾香, 松井 まゆ, 村上 雅一, 杉田 光士郎, 矢野 圭輔, 春松 敏夫, 山田 耕嗣, 山田 和歌, 松久保 眞, 武藤 充, 加治 建

    小児外科   53 ( 3 )   303 - 307   2021.3

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