Updated on 2023/10/23

写真a

 
SAKIMOTO Hitoshi
 
Organization
University Hospital, Medical and Dental Sciences Area University Hospital Clinical Center Mental Care Center Assistant Professor
Title
Assistant Professor

Degree

  • 博士(医学) ( 2017.3   鹿児島大学 )

Research History

  • Kagoshima University   Medical and Dental Hospital, Medical and Dental Sciences Area Medical and Dental Hospital Clinical Center Mental Care Center   Assistant Professor

    2018.4

  • Kagoshima University   Medical and Dental Hospital, Medical and Dental Sciences Area Medical and Dental Hospital Clinical Center Mental Care Center   Assistant Professor

    2018.1 - 2018.3

 

Papers

  • Sakimoto Hitoshi, Urata Yuka, Ishizuka Takanori, Kimotsuki Hiroshi, Kasugai Motofumi, Fukuhara Ryuji, Sano Akira, Nakamura Masayuki .  Association of auditory Charles Bonnet syndrome with increased blood flow in the nondominant Brodmann area 22(タイトル和訳中) .  Psychiatry and Clinical Neurosciences Reports2 ( 2 ) 1 of 8 - 8 of 8   2023.6Association of auditory Charles Bonnet syndrome with increased blood flow in the nondominant Brodmann area 22(タイトル和訳中)

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    Language:English   Publisher:John Wiley & Sons Australia, Ltd  

  • Arai K., Sakimoto H., Urata Y., Kariya M., Nakamura T., Ikehata T., Shimojima R., Furue N., Ishizuka T., Sano A., Nakamura M. .  Aging-Related Catatonia with Reversible Dopamine Transporter Dysfunction in Females with Depressive Symptoms: A Case Series .  American Journal of Geriatric Psychiatry   2023

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    Language:Japanese   Publisher:American Journal of Geriatric Psychiatry  

    Objectives: The authors describe five depressive patients with initially decreased striatal accumulation of dopamine transporter (DAT) single-photon emission computed tomography (SPECT), which improved in parallel with clinical symptoms. Methods: Patients who exhibited decreased striatal accumulation and recovery of DATSPECT were identified among patients with the symptoms of depression. Their clinical and neuroimaging data were reviewed. Results: Five patients were identified. All patients were presenile or senile women who presented with catatonia subsequent to symptoms of depression that remitted with treatment. DAT-SPECT showed a decreased striatal accumulation in all patients, which increased after treatment. Two patients had met the diagnostic criteria of probable dementia with Lewy bodies (DLB), but no longer did so after their symptoms improved. Conclusions: Reversible DAT dysfunction observed in this study suggests that reversible impairment of dopaminergic transmission in the striatum partly underlies catatonia. Careful consideration should be given to diagnosing DLB in patients with decreased DAT-SPECT accumulation, especially when catatonia is present.

    DOI: 10.1016/j.jagp.2023.05.009

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    PubMed

  • Ebata Naoyuki, Fukumoto Shinya, Kashima Masayuki, Watanabe Mutumi, Sakimoto Hitoshi, Ishizuka Takanori, Nakamura Masayuki .  A Study on Automatic State Estimation during Sleep by Comprehensive Image Analysis .  Transactions of Japanese Society for Medical and Biological EngineeringAnnual59 ( Abstract ) 420 - 420   2021A Study on Automatic State Estimation during Sleep by Comprehensive Image Analysis

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    Language:Japanese   Publisher:Japanese Society for Medical and Biological Engineering  

    <p>According to a survey conducted by the Ministry of Health, Labor and Welfare, one in five Japanese people say that they do not get enough rest from sleep, and there is a growing need to ensure restful sleep based on objective evaluation of sleep status. Polysomnography is a method of measuring sleep state, but it is used for medical purposes and requires many sensors such as electroencephalogram, eye movement, etc., making it difficult to measure at home on a daily basis. In this study, we aimed to develop a method for unconstrained and reliable sleep stage estimation by integrating and analyzing video information from two viewpoints. We apply machine learning to the feature extraction results of thorax motion, body movement, and apnea from the horizontal viewpoint, and the feature extraction results of nasal skin temperature from the frontal viewpoint. We confirmed the effectiveness of the proposed method through evaluation experiments.</p>

    DOI: 10.11239/jsmbe.annual59.420

  • Hitoshi Sakimoto, Masayuki Nakamura, Oomi Nagata, Akira Sanoa .  Phenotypic abnormalities in a chorea-acanthocytosis mouse model are modulated by strain background .      2017.3Phenotypic abnormalities in a chorea-acanthocytosis mouse model are modulated by strain backgroundReviewed

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    Language:English   Publishing type:Doctoral thesis  

    有棘赤血球舞踏病(Chorea-acanthocytosis; ChAc)はHuntington病類似の舞踏運動と多彩な精神症状を呈し、末梢血有棘赤血球症が成人期に発症する稀な常染色体劣性遺伝性の神経変性疾患である。我々のグループは、以前の研究でVPS13A遺伝子上のエクソン60と61を欠失する疾患変異であるEhime-欠失変異を同定し、同変異をマウスに導入することにより、ChAcモデルマウスを作成した。背景ストレインがC57BL/6、129S6、BALB/c、FVBの4系統を作成し行動実験を行った。ストレインにより表現型に差異があり、表現型の差異が生じる原因としては、マウス系統の背景遺伝子差中にChAcの症状修飾因子が存在することが示唆された。