Organization
Research Field in Medicine and Health Sciences, Medical and Dental Sciences Area Graduate School of Medical and Dental Sciences Advanced Therapeutics Course Oncology Assistant Professor
Title
Assistant Professor
Taiji Hamada
Degree
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Doctor (philosophy in medical science) ( 2015.8 Kagoshima University )
Research Interests
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genome editing
Research Areas
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Life Science / Molecular biology
Research History
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Kagoshima University Research Field in Medicine and Health Sciences, Medical and Dental Sciences Area Graduate School of Medical and Dental Sciences Advanced Therapeutics Course Oncology Assistant Professor
2018.1
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Kagoshima University Research Field in Medicine and Health Sciences, Medical and Dental Sciences Area Graduate School of Medical and Dental Sciences Advanced Therapeutics Course Oncology
2013.12 - 2017.12
Professional Memberships
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The Japanese Society for Genome Editing
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The Molecular Biology Society of Japan
Papers
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Kitazono I, Hamada T, Yoshimura T, Kirishima M, Yokoyama S, Akahane T, Tanimoto A . PCP4/PEP19 downregulates neurite outgrowth via transcriptional regulation of Ascl1 and NeuroD1 expression in human neuroblastoma M17 cells. . Laboratory investigation; a journal of technical methods and pathology100 ( 12 ) 1551 - 1563 2020.12PCP4/PEP19 downregulates neurite outgrowth via transcriptional regulation of Ascl1 and NeuroD1 expression in human neuroblastoma M17 cells.
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Nayuta Higa, Toshiaki Akahane, Seiya Yokoyama, Hajime Yonezawa, Hiroyuki Uchida, Tomoko Takajo, Mari Kirishima, Taiji Hamada, Kei Matsuo, Shingo Fujio, Tomoko Hanada, Hiroshi Hosoyama, Masanori Yonenaga, Akihisa Sakamoto, Tsubasa Hiraki, Akihide Tanimoto, Koji Yoshimoto. . A tailored next-generation sequencing panel identified distinct subtypes of wildtype IDH and TERT promoter glioblastomas. . Cancer Science 2020.8A tailored next-generation sequencing panel identified distinct subtypes of wildtype IDH and TERT promoter glioblastomas.Reviewed
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Ikumi Kitazono, Taiji Hamada, Takuya Yoshimura, Mari Kirishima, Seiya Yokoyama, Toshiaki Akahane, Akihide Tanimoto. . PCP4/PEP19 downregulates neurite outgrowth via transcriptional regulation of Ascl1 and NeuroD1 expression in human neuroblastoma M17 cells. . Laboratory Investigation 2020.7PCP4/PEP19 downregulates neurite outgrowth via transcriptional regulation of Ascl1 and NeuroD1 expression in human neuroblastoma M17 cells.Reviewed
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Yokoyama S, Hamada T, Higashi M, Matsuo K, Maemura K, Kurahara H, Horinouchi M, Hiraki T, Sugimoto T, Akahane T, Yonezawa S, Kornmann M, Batra SK, Hollingsworth MA, Tanimoto A . Predicted Prognosis of Patients with Pancreatic Cancer by Machine Learning. . Clinical cancer research : an official journal of the American Association for Cancer Research26 ( 10 ) 2411 - 2421 2020.5Predicted Prognosis of Patients with Pancreatic Cancer by Machine Learning.
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Seiya Yokoyama, Taiji Hamada, Michiyo Higashi, Kei Matsuo, Kosei Maemura, Hiroshi Kurahara, Michiko Horinouchi, Tsubasa Hiraki, Tomoyuki Sugimoto, Toshiaki Akahane, Suguru Yonezawa, Marko Kornmann, Surinder K Batra, Michael A Hollingsworth, Akihide Tanimoto. . Predicted Prognosis of Patients With Pancreatic Cancer by Machine Learning. . Clinical Cancer Research 2020.5Predicted Prognosis of Patients With Pancreatic Cancer by Machine Learning.Reviewed
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Guo X, Noguchi H, Ishii N, Homma T, Hamada T, Hiraki T, Zhang J, Matsuo K, Yokoyama S, Ishibashi H, Fukushige T, Kanekura T, Fujii J, Uramoto H, Tanimoto A, Yamada S . The Association of Peroxiredoxin 4 with the Initiation and Progression of Hepatocellular Carcinoma. . Antioxidants & redox signaling30 ( 10 ) 1271 - 1284 2019.4The Association of Peroxiredoxin 4 with the Initiation and Progression of Hepatocellular Carcinoma.
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Akahane T, Yamaguchi T, Kato Y, Yokoyama S, Hamada T, Nishida Y, Higashi M, Nishihara H, Suzuki S, Ueno S, Tanimoto A . Comprehensive validation of liquid-based cytology specimens for next-generation sequencing in cancer genome analysis. . PloS one14 ( 6 ) e0217724 2019Comprehensive validation of liquid-based cytology specimens for next-generation sequencing in cancer genome analysis.Invited Reviewed
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Zhang J, Guo X, Hamada T, Yokoyama S, Nakamura Y, Zheng J, Kurose N, Ishigaki Y, Uramoto H, Tanimoto A, Yamada S . Protective Effects of Peroxiredoxin 4 (PRDX4) on Cholestatic Liver Injury. . International journal of molecular sciences19 ( 9 ) 2018.8Protective Effects of Peroxiredoxin 4 (PRDX4) on Cholestatic Liver Injury.
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Onishi S, Kaji T, Yamada W, Nakame K, Machigashira S, Kawano M, Yano K, Harumatsu T, Yamada K, Masuya R, Kawano T, Mukai M, Hamada T, Souda M, Yoshioka T, Tanimoto A, Ieiri S . Ghrelin stimulates intestinal adaptation following massive small bowel resection in parenterally fed rats. . Peptides106 59 - 67 2018.8Ghrelin stimulates intestinal adaptation following massive small bowel resection in parenterally fed rats.
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Honjo K, Hamada T, Yoshimura T, Yokoyama S, Yamada S, Tan YQ, Leung LK, Nakamura N, Ohi Y, Higashi M, Tanimoto A . PCP4/PEP19 upregulates aromatase gene expression via CYP19A1 promoter I.1 in human breast cancer SK-BR-3 cells. . Oncotarget9 ( 51 ) 29619 - 29633 2018.7PCP4/PEP19 upregulates aromatase gene expression via CYP19A1 promoter I.1 in human breast cancer SK-BR-3 cells.Invited Reviewed
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Yamada S, Kawaguchi H, Yamada T, Guo X, Matsuo K, Hamada T, Miura N, Tasaki T, Tanimoto A . Cholic Acid Enhances Visceral Adiposity, Atherosclerosis and Nonalcoholic Fatty Liver Disease in Microminipigs. . Journal of atherosclerosis and thrombosis24 ( 11 ) 1150 - 1166 2017.11Cholic Acid Enhances Visceral Adiposity, Atherosclerosis and Nonalcoholic Fatty Liver Disease in Microminipigs.
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Yokoyama S, Higashi M, Tsutsumida H, Wakimoto J, Hamada T, Wiest E, Matsuo K, Kitazono I, Goto Y, Guo X, Hamada T, Yamada S, Hiraki T, Yonezawa S, Batra SK, Hollingsworth MA, Tanimoto A . TET1-mediated DNA hypomethylation regulates the expression of MUC4 in lung cancer. . Genes & cancer8 ( 3-4 ) 517 - 527 2017.3TET1-mediated DNA hypomethylation regulates the expression of MUC4 in lung cancer.
Research Projects
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乳癌を標的とした新規アロマターゼ阻害剤の開発に向けた基盤研究
2018.4 - 2021.3
科学研究費補助金 基盤研究(C)