Ishii M, Ikeda N, Miyata H, Takahashi M, Nishimura M. .  Purple Sweet Potato Leaf Extracts Suppress Adipogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells. .  Journal of Food Biochemistry   2022.1Purple Sweet Potato Leaf Extracts Suppress Adipogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells.Reviewed

Suehiro F, Komabashiri N, Masuzaki T, Ishii M, Yanagisawa T, Nishimura M .  Efficacy of bone grafting materials in preserving the alveolar ridge in a canine model. .  Dental Materials Journal   2021.12Efficacy of bone grafting materials in preserving the alveolar ridge in a canine model.Reviewed

Yanagisawa T, Ishii M, Takahashii M, Fujishima K, Nishimura M. .  Human cathelicidin antimicrobial peptide LL-37 promotes lymphangiogenesis in lymphatic endothelial cells through the ERK and Akt signaling pathways. .  Molecular Biology Reports47   6841 - 6854   2020.9Human cathelicidin antimicrobial peptide LL-37 promotes lymphangiogenesis in lymphatic endothelial cells through the ERK and Akt signaling pathways.Reviewed

Ishii M, Takahashi M, Murakami J, Yanagisawa T, Nishimura M. .  Vascular Endothelial Growth Factor-C Promotes Human Mesenchymal Stem Cell Migration via an ERK-and FAK-dependent Mechanism. .  Molecular and Cellular Biochemistry455 ( 1-2 ) 185 - 193   2018.11Vascular Endothelial Growth Factor-C Promotes Human Mesenchymal Stem Cell Migration via an ERK-and FAK-dependent Mechanism.Reviewed

Shimizu Y, Polavarapu R, Eskla KL, Pantner Y, Nicholson CK, Ishii M, Brunnhoelzl D, Mauria R, Husain A, Naqvi N, Murohara T, Calvert JW. .  Impact of Lymphangiogenesis on Cardiac Remodeling After Ischemia and Reperfusion Injury. .  Journal of the American Heart Association.7   e009565   2018.9Impact of Lymphangiogenesis on Cardiac Remodeling After Ischemia and Reperfusion Injury.Reviewed

Ishii M, Nakahara T, Araho D, Murakami J, Nishimura M. .  Glycolipids from spinach suppress LPS-induced vascular inflammation through eNOS and NK-κB signaling. .  Biomedicine & Pharmacotherapy91   111 - 120   2017.4Glycolipids from spinach suppress LPS-induced vascular inflammation through eNOS and NK-κB signaling.Reviewed

Murakami J, Ishii M, Suehiro F, Ishihata K, Nakamura N, Nishimura M. .  Vascular Endothelial Growth Factor-C Induces Osteogenic Differentiation of Human Mesenchymal Stem Cells through the ERK and RUNX2 Pathway. .  Biochemical and Biophysical Research Communications.484 ( 3 ) 710 - 718   2017.2Vascular Endothelial Growth Factor-C Induces Osteogenic Differentiation of Human Mesenchymal Stem Cells through the ERK and RUNX2 Pathway.Reviewed

Suehiro F, Ishii M, Asahina I, Murata H, Nishimura M. .  Low-serum culture with novel medium promotes maxillary/mandibular bone marrow stromal cell proliferation and osteogenic differentiation ability. .  Clinical Oral Investigations.   2017.2Low-serum culture with novel medium promotes maxillary/mandibular bone marrow stromal cell proliferation and osteogenic differentiation ability.Reviewed

Ishii M, Nakahara T, Ikeuchi S, Nishimura M. .  β-Amyrin induces angiogenesis in vascular endothelial cells through the Akt/endothelial nitric oxide synthase signaling pathway. .  Biochemical and Biophysical Research Communications467 ( 4 ) 676 - 682   2015.10β-Amyrin induces angiogenesis in vascular endothelial cells through the Akt/endothelial nitric oxide synthase signaling pathway.Reviewed

Niwa M, Numaguchi Y, Ishii M, Kuwahata T, Kondo M, Shibata R, Miyata K, Oike Y, Murohara T. .  IRAP Deficiency Attenuates Diet-induced Obesity in Mice Through Increased Energy Expenditure. .  Biochemical and Biophysical Research Communications457 ( 1 ) 12 - 18   2015.1IRAP Deficiency Attenuates Diet-induced Obesity in Mice Through Increased Energy Expenditure.Reviewed

Ishii M, Shibata R, Kondo K, Kambara T, Shimizu Y, Tanigawa T, Bando-Kureishi, Y, Nishimura M, Ouchi N, Murohara T. .  Vildagliptin stimulates endothelial cell network formation and ischemia-induced revascularization via an endothelial nitric oxide synthase-dependent mechanism. .  The Journal of Biological Chemistry.289 ( 39 ) 27235 - 27245   2014.9Vildagliptin stimulates endothelial cell network formation and ischemia-induced revascularization via an endothelial nitric oxide synthase-dependent mechanism.Reviewed

Hao CN, Shintani S, Shimizu Y, Kondo K, Ishii M, Wu H, Murohara T. .  Therapeutic Angiogenesis by Autologous Adipose-Derived Regenerative Cells: Comparison With Bone Marrow Mononuclear Cells. .  American Journal of Physiology. Heart and Circulatory Physiology.307 ( 6 ) H869 - H879   2014.9Therapeutic Angiogenesis by Autologous Adipose-Derived Regenerative Cells: Comparison With Bone Marrow Mononuclear Cells.Reviewed

Ishii M, Shibata R, Shimizu Y, Yamamoto T, Kondo K, Inoue Y, Ouchi N, Tanigawa T, Kanemura N, Ito A, Honda H, Murohara T. .  Multilayered adipose-derived regenerative cell sheets created by a novel magnetic tissue engineering method for myocardial infarction. .  International Journal of Cardiology.175 ( 3 ) 545 - 553   2014.8Multilayered adipose-derived regenerative cell sheets created by a novel magnetic tissue engineering method for myocardial infarction.Reviewed

Tanigawa T, Shibata R, Ouchi N, Kondo K, Ishii M, Katahira N, Kambara T, Inoue Y, Takahashi R, Ikeda N, Kihara S, Ueda H, Murohara T. .  Adiponectin deficiency exacerbates age-related hearing impairment. .  Cell Death & Disease5   e1189   2014.4Adiponectin deficiency exacerbates age-related hearing impairment.Reviewed

Shimizu Y, Shibata R, Ishii M, Ohashi K, Kambara T, Uemura Y, Yuasa D, Kataoka Y, Kihara S, Murohara T, Ouchi N. .  Adiponectin-mediated modulation of lymphatic vessel formation and lymphedema. .  Journal of the American Heart Association.2 ( 5 ) e000438   2013.9Adiponectin-mediated modulation of lymphatic vessel formation and lymphedema.Reviewed

Yamamoto T, Shibata R, Ishii M, Kanemura N, Kito T, Suzuki H, Miyake H, Maeda K, Tanigawa T, Ouchi N, Murohara T. .  Therapeutic Reendothelialization by Induced Pluripotent Stem Cells After Vascular Injury. .  Arteriosclerosis, Thrombosis, and Vascular Biology.33 ( 9 ) 2218 - 2221   2013.9Therapeutic Reendothelialization by Induced Pluripotent Stem Cells After Vascular Injury.Reviewed

Ogura Y, Ouchi N, Ohashi K, Shibata R, Kataoka Y, Kambara T, Kito T, Maruyama S, Yuasa D, Matsuo K, Enomoto T, Uemura Y, Miyabe M, Ishii M, Yamamoto T, Shimizu Y, Walsh K, Murohara T. .  Therapeutic Impact of Follistatin-like 1 on Myocardial Ischemic Injury in Preclinical Animal Models. .  Circulation.126 ( 14 ) 1728 - 1738   2013.8Therapeutic Impact of Follistatin-like 1 on Myocardial Ischemic Injury in Preclinical Animal Models.Reviewed

Shimizu Y, Shibata R, Shintani S, Ishii M, Murohara T .  Therapeutic Lymphangiogenesis With Implantation of Adipose-Derived Regenerative Cells. .  Journal of the American Heart Association.1 ( 4 ) e000877   2013.8Therapeutic Lymphangiogenesis With Implantation of Adipose-Derived Regenerative Cells.Reviewed

Suzuki H, Shibata R, Kito T, Yamamoto T, Ishii M, Nishio N, Ito S, Isobe K, Murohara T. .  Comparative angiogenic activities of induced pluripotent stem cells derived from young and old mice. .  PLoS One.7 ( 6 ) e39562   2013.6Comparative angiogenic activities of induced pluripotent stem cells derived from young and old mice.Reviewed

Kito T, Shibata R, Ishii M, Suzuki H, Himeno T, Kataoka Y, Yamamura Y, Yamamoto T, Nishio N, Ito S, Numaguchi Y, Tanigawa T, Yamashita JK, Ouchi N, Honda H, Isobe K, Murohara T. .  iPS cell sheets created by a novel magnetite tissue engineering method for reparative angiogenesis. .  Scientific Reports.3   1418   2013.3iPS cell sheets created by a novel magnetite tissue engineering method for reparative angiogenesis.Reviewed

Kito T, Shibata R, Kondo M, Yamamoto T, Suzuki H, Ishii M, Murohara T. .  Nifedipine Ameliorates Ischemia-Induced Revascularization in Diet-Induced Obese Mice. .  American Journal of Hypertensions.25 ( 4 ) 401 - 406   2012.4Nifedipine Ameliorates Ischemia-Induced Revascularization in Diet-Induced Obese Mice.Reviewed

Ishii M, Shibata R, Numaguchi Y, Kito T, Suzuki H, Shimizu K, Ito A, Honda H, Murohara T. .  Enhanced Angiogenesis by Transplantation of Mesenchymal Stem Cell Sheet Created by a Novel Magnetic Tissue Engineering Method. .  Arteriosclerosis, Thrombosis, and Vascular Biology.31 ( 10 ) 2210 - 2215   2011.10Enhanced Angiogenesis by Transplantation of Mesenchymal Stem Cell Sheet Created by a Novel Magnetic Tissue Engineering Method.Reviewed

Kubota R, Numaguchi Y, Ishii M, Niwa M, Okumura K, Naruse K, Murohara T. .  Ischemia-induced angiogenesis is impaired in aminopeptidase A-deficient mice via down-regulation of HIF-1α. .  Biochemical and Biophysical Research Communications.402 ( 2 ) 396 - 401   2010.11Ischemia-induced angiogenesis is impaired in aminopeptidase A-deficient mice via down-regulation of HIF-1α.Reviewed

Suzuki H, Shibata R, Kito T, Ishii M, Li P, Yoshikai T, Nishio N, Ito S, Numaguchi Y, Yamashita JK, Murohara T, Isobe K. .  Therapeutic angiogenesis by transplantation of induced pluripotent stem cell-derived Flk-1 positive cells. .  BMC Cell Biology.11 ( 1 ) 72   2010.9Therapeutic angiogenesis by transplantation of induced pluripotent stem cell-derived Flk-1 positive cells.Reviewed

Ito S, Suki B, Kume H, Numaguchi Y, Ishii M, Iwaki M, Kondo M, Naruse K, Hasegawa Y, Sokabe M. .  Actin Cytoskeleton Regulates Stretch-activated Ca2+ Influx in Human Pulmonary Microvascular Endothelial Cells. .  American Journal of Respiratory Cell and Molecular Biology.43 ( 1 ) 26 - 34   2010.7Actin Cytoskeleton Regulates Stretch-activated Ca2+ Influx in Human Pulmonary Microvascular Endothelial Cells.Reviewed

Shumiya T, Shibata R, Shimizu Y, Ishii M, Kubota R, Shintani S, Murohara T. .  Evidence for the Therapeutic Potential of ex Vivo Expanded Human Endothelial Progenitor Cells Using Autologous Serum. .  Circulation Journal.74 ( 5 ) 1006 - 1013   2010.5Evidence for the Therapeutic Potential of ex Vivo Expanded Human Endothelial Progenitor Cells Using Autologous Serum.Reviewed

Kondo K, Shibata R, Unno K, Shimano M, Ishii M, Kito T, Shintani S, Walsh K, Ouchi N, Murohara T. .  Impact of a Single Intracoronary Administration of Adiponectin on Myocardial Ischemia/Reperfusion Injury in a Pig Model. .  Circulation. Cardiovascular Interventions.3 ( 2 ) 166 - 173   2010.4Impact of a Single Intracoronary Administration of Adiponectin on Myocardial Ischemia/Reperfusion Injury in a Pig Model.Reviewed

Numaguchi Y, Ishii M, Kubota R, Morita Y, Yamamoto K, Matsushita T, Okumura K, Murohara T. .  Ablation of Angiotensin IV Receptor Attenuates Hypofibrinolysis via PAI-1 Downregulation and Reduces Occlusive Arterial Thrombosis. .  Arteriosclerosis, Thrombosis, and Vascular Biology.29 ( 12 ) 2102 - 2108   2009.12Ablation of Angiotensin IV Receptor Attenuates Hypofibrinolysis via PAI-1 Downregulation and Reduces Occlusive Arterial Thrombosis.Reviewed

Iwaki M, Morioka M, Iwata S, Numaguchi Y, Ishii M, Kondo M, Kume H, Naruse K, Sokabe M, Hasegawa Y. .  Mechanical stretch enhances IL-8 production in pulmonary microvascular endothelial cells. .  Biochemical and Biophysical Research Communications.389 ( 3 ) 531 - 536   2009.11Mechanical stretch enhances IL-8 production in pulmonary microvascular endothelial cells.Reviewed

Ishii M, Hattori A, Numaguchi Y, Ma X, Nagasaka T, Tsujimoto M, Murohara T, Kobayashi H, Mizutani S. .  The effect of recombinant aminopeptidase A (APA) on hypertension in pregnant spontaneously hypertensive rats (SHRs). .  Early Human Development.85 ( 9 ) 589 - 594   2009.9The effect of recombinant aminopeptidase A (APA) on hypertension in pregnant spontaneously hypertensive rats (SHRs).Reviewed

Ishii M, Numaguchi Y, Okumura K, Kubota R, Ma X, Murakami R, Naruse K, Murohara T. .  Mesenchymal Stem Cell-Based Gene Therapy with Prostacyclin Synthase Enhanced Neovascularization in Hindlimb Ischemia. .  Atherosclerosis.206 ( 1 ) 109 - 118   2009.9Mesenchymal Stem Cell-Based Gene Therapy with Prostacyclin Synthase Enhanced Neovascularization in Hindlimb Ischemia.Reviewed

Miura M, Numaguchi Y, Ishii M, Kubota R, Takeuchi T, Imamura A, Murakami R, Kondo T, Okumura K, Murohara T. .  Differentiation capacity of endothelial progenitorcells correlates with endothelial function in healthy young men. .  Circulation Journal.73 ( 7 ) 1324 - 1329   2009.7Differentiation capacity of endothelial progenitorcells correlates with endothelial function in healthy young men.Reviewed

Ishii M, Naruse K, Hattori A, Tsujimoto M, Ishiura S, Numaguchi Y, Murohara T, Kobayashi H, Mizutani S. .  Oxytocin Hypersensitivity in Pregnant P-LAP Deficient Mice. .  Life Sciences.84 ( 19-20 ) 668 - 672   2009.5Oxytocin Hypersensitivity in Pregnant P-LAP Deficient Mice.Reviewed

Ishii M, Hattori A, Numaguchi Y, Tsujimoto M, Ishiura S, Kobayashi H, Murohara T, Wright J W, Mizutani S. .  The Effect of Recombinant Aminopeptidase A (APA) on Hypertension in Spontaneously Hypertensive Rats (SHRs): Its Effect in Comparison with Candesartan. .  Hormon and Metabolic Research.40 ( 12 ) 887 - 891   2008.12The Effect of Recombinant Aminopeptidase A (APA) on Hypertension in Spontaneously Hypertensive Rats (SHRs): Its Effect in Comparison with Candesartan.Reviewed

Shibata R, Numaguchi Y, Matsushita K, Sone T, Kubota R, Ohashi T, Ishii M, Kihara S, Walsh K, Ouchi N, Murohara T. .  Usefulness of adiponectin to predict myocardial salvage following successful reperfusion in patients with acute myocardial infarction. .  American Journal of Cardiology.101 ( 12 ) 1712 - 1715   2008.6Usefulness of adiponectin to predict myocardial salvage following successful reperfusion in patients with acute myocardial infarction.Reviewed

Imai H, Numaguchi Y, Ishii M, Kubota R, Yokouchi K, Ogawa Y, Kondo T, Okumura K, Murohara T. .  Prostacyclin synthase gene transfer inhibits neointimal formation by suppressing PPARdelta expression. .  Atherosclerosis.195 ( 2 ) 322 - 332   2007.12Prostacyclin synthase gene transfer inhibits neointimal formation by suppressing PPARdelta expression.Reviewed

Mizutani S, Shibata K, Kikkawa F, Hattori A, Tsujimoto M, Ishii M, Kobayashi H. .  Essential role of placental leucine aminopeptidase in gynecologic malignancy. .  Expert Opinion on Therapeutic Targets.11 ( 4 ) 453 - 461   2007.4Essential role of placental leucine aminopeptidase in gynecologic malignancy.Reviewed

Yokouchi K, Numaguchi Y, Kubota R, Ishii M, Imai H, Murakami R, Ogawa Y, Kondo T, Okumura K, Ingber DE, Murohara T. .  l-Caldesmon regulates proliferation and migration of vascular smooth muscle cells and inhibits neointimal formation after angioplasty. .  Arteriosclerosis, Thrombosis, and Vascular Biology.26 ( 10 ) 2231 - 2237   2006.10l-Caldesmon regulates proliferation and migration of vascular smooth muscle cells and inhibits neointimal formation after angioplasty.Reviewed

Numaguchi Y, Sone T, Okumura K, Ishii M, Morita Y, Kubota R, Yokouchi K, Imai H, Harada M, osanai H, Kondo T, Murohata T. .  The impact of the capability of circulating progenitor cell to differentiate on myocardial salvage in patients with primary acute myocardial infarction. .  Circulation.114 ( 1 Suppl ) I114 - I119   2006.7The impact of the capability of circulating progenitor cell to differentiate on myocardial salvage in patients with primary acute myocardial infarction.Reviewed

Matsubara T, Suardita K, Ishii M, Sugiyama M, Igarashi A, Oda R, Nishimura M, Saito M, Nakagawa K, Yamanaka K, Miyazaki K, Shimizu M, Bhawal UK, Tsuji K, Nakamura K, Kato Y. .  Alveolar bone marrow as a cell source for regenerative medicine: differences between alveolar and iliac bone marrow stromal cells. .  Journal of Bone and Mineral Research.20 ( 3 ) 399 - 409   2005.3Alveolar bone marrow as a cell source for regenerative medicine: differences between alveolar and iliac bone marrow stromal cells.Reviewed

石井正和、沼口靖、窪田龍二、横内一彦、近藤隆久、室原豊明   Multilayerd Mesenchymal Stem Cell Sheet Constructed Using Magnetite Nanoparticle Improves Mice Hind Limb Ischemia  

第72回日本循環器学会総会  第72回日本循環器学会総会

石井正和、沼口靖、窪田龍二、井藤彰、室原豊明   磁性ナノ粒子を用いた間葉系幹細胞シートの下肢虚血治療への応用  

第15回日本血管生物医学会  第15回日本血管生物医学会

Ishii M, Numaguchi Y, Kubota R, Yokouchi K, Ogawa Y, Okumura K, Murohara T   Local Delivery of Bone Marrow Derived Stromal Cells Engineered to Overexpress Prostacyclin Synthase Enhanced Collateral Perfusion in Hindlimb Ischemia.   International conference

American College of Cardiology 55th Annual scientific session.  American College of Cardiology 55th Annual scientific session.

Ishii M, Hattori A, Hattori C, Numaguchi Y, Tsujimoto M, Ishiura S, Kobayashi H, Murohara T, Mizutani S.   Anti-hypertensive effect of recombinant aminopeptidase A (AP-A) in spontaneously hypertensive rats (SHRs)   International conference

The 21st Scientific Meeting of the International Society of Hypertension.  The 21st Scientific Meeting of the International Society of Hypertension.

石井正和、沼口靖、窪田龍二、横内一彦、近藤隆久、室原豊明   マウス下肢虚血モデルにおけるPGI2合成酵素と骨髄由来間葉系幹細胞を用いた強化細胞療法の有効性  

第５回日本再生医療学会  第５回日本再生医療学会

石井正和、沼口靖、窪田龍二、横内一彦、近藤隆久、室原豊明   下肢虚血モデルにおける循環調節プロスタノイドと骨髄由来間葉系幹細胞を用いたハイブリット細胞療法の有効性  

第１３回日本血管生物医学会  第１３回日本血管生物医学会