Updated on 2024/10/03

写真a

 
Ikue Kusumoto-Yoshida
 
Organization
Research Field in Medicine and Health Sciences, Medical and Dental Sciences Area Graduate School of Medical and Dental Sciences Advanced Therapeutics Course Functional Biology and Pharmacology Assistant Professor
Title
Assistant Professor

Degree

  • Ph.D. (Medical Science) ( 2009.3   The University of Tokyo )

  • Master (Medical Science) ( 2005.3   The University of Tokyo )

  • Bachelor (Human Life and Environment) ( 2003.3   Nara Women's University )

Research Interests

  • chemogenetics

  • optogenetics

  • behavioral assay

  • insular cortex

  • Appetite

Research Areas

  • Others / Others  / 神経科学

Education

  • The University of Tokyo

    2005.4 - 2009.3

      More details

    Country: Japan

  • The University of Tokyo

    2003.4 - 2005.3

Research History

  • Kagoshima University   Assistant Professor

    2013.10

Professional Memberships

  • 日本味と匂学会

    2015.10

  • 日本生理学会

    2015.10

  • 北米神経科学会

    2015.10

  • 日本神経科学会

    2015.10

Studying abroad experiences

  • 2010.10 - 2013.9   National Institute of Health, NIDA IRP   postdoctoral fellow

 

Papers

  • Uchino E, Kusumoto-Yoshida I, Kashiwadani H, Kanmura Y, Matsunaga A, Kuwaki T .  Identification of hypothermia-inducing neurons in the preoptic area and activation of them by isoflurane anesthesia and central injection of adenosine. .  The journal of physiological sciences : JPS74 ( 1 ) 33   2024.6Identification of hypothermia-inducing neurons in the preoptic area and activation of them by isoflurane anesthesia and central injection of adenosine.

     More details

    Language:English  

    DOI: 10.1186/s12576-024-00927-2

    PubMed

  • Kaneko T, Oura A, Imai Y, Kusumoto-Yoshida I, Kanekura T, Okuno H, Kuwaki T, Kashiwadani H .  Orexin neurons play contrasting roles in itch and pain neural processing via projecting to the periaqueductal gray. .  Communications biology7 ( 1 ) 290   2024.3Orexin neurons play contrasting roles in itch and pain neural processing via projecting to the periaqueductal gray.

     More details

    Language:English  

    DOI: 10.1038/s42003-024-05997-x

    PubMed

  • Ma J, Yanase S, Udagawa L, Kuwaki T, Kusumoto-Yoshida I .  Activation of neurons in the insular cortex and lateral hypothalamus during food anticipatory period caused by food restriction in mice. .  The journal of physiological sciences : JPS73 ( 1 ) 34   2023.12Activation of neurons in the insular cortex and lateral hypothalamus during food anticipatory period caused by food restriction in mice.

     More details

    Language:English  

    DOI: 10.1186/s12576-023-00892-2

    PubMed

  • Kawashima S, Lou F, Kusumoto-Yoshida I, Hao L, Kuwaki T .  Activation of the rostral nucleus accumbens shell by optogenetics induces cataplexy-like behavior in orexin neuron-ablated mice. .  Scientific reports13 ( 1 ) 2546   2023.2Activation of the rostral nucleus accumbens shell by optogenetics induces cataplexy-like behavior in orexin neuron-ablated mice.

     More details

    Language:English  

    DOI: 10.1038/s41598-023-29488-x

    PubMed

  • Miyata K, Ikoma Y, Murata K, Kusumoto-Yoshida I, Kobayashi K, Kuwaki T, Ootsuka Y .  Multifaceted roles of orexin neurons in mediating methamphetamine-induced changes in body temperature and heart rate. .  IBRO neuroscience reports12   108 - 120   2022.6Multifaceted roles of orexin neurons in mediating methamphetamine-induced changes in body temperature and heart rate.

     More details

    Language:English  

    DOI: 10.1016/j.ibneur.2022.01.002

    PubMed

  • Jingyang Su, Zhi Li, Akira Yamashita, Ikue Kusumoto-Yoshida, Takuto Isomichi, Liying Hao, Tomoyuki Kuwaki .  Involvement of the Nucleus Accumbens in Chocolate-induced Cataplexy. .  Scientific Reports   2020Involvement of the Nucleus Accumbens in Chocolate-induced Cataplexy.Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Yoko Ikoma, Ikue Kusumoto-Yoshida, Akihiro Yamanaka, Youichirou Ootsuka and Tomoyuki Kuwaki .  Inactivation of serotonergic neurons in the rostral medullary raphe attenuates stress induced tachypnea and tachycardia in mice .  Frontiers in Physiology   2018.7Inactivation of serotonergic neurons in the rostral medullary raphe attenuates stress induced tachypnea and tachycardia in miceReviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3389/fphys.2018.00832

  • Ueda H1, Suga M1, Yagi T1, Kusumoto-Yoshida I2, Kashiwadani H2, Kuwaki T2, Miyawaki S3. .  Vagal afferent activation induces salivation and swallowing-like events in anesthetized rats. .  American journal of physiology. Regulatory, integrative and comparative physiology311 ( 5 ) 964 - 970   2016.11Vagal afferent activation induces salivation and swallowing-like events in anesthetized rats.Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1152/ajpregu.00292.2016

  • Ikue Kusumoto-Yoshida, Haixin Liu, Billy T. Chen, Alfredo Fontanini, and Antonello Bonci .  A central role for the insular cortex in mediating conditioned responses to anticipatory cues .  Proceedings of National Academy Sciences U S A.112 ( 4 ) 1190 - 1195   2015.1A central role for the insular cortex in mediating conditioned responses to anticipatory cuesReviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Komano-Inoue Sayaka, Manabe Hiroyuki, Ota Mizuho, Kusumoto-Yoshida Ikue, Yokoyama K Takeshi, Mori Kensaku, Yamaguchi Masahiro .  Top-down inputs from the olfactory cortex in the postprandial period promote elimination of granule cells in the olfactory bulb. .  European Journal of Neuroscience40 ( 5 ) 2724 - 2733   2014.7Top-down inputs from the olfactory cortex in the postprandial period promote elimination of granule cells in the olfactory bulb.Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Billy T Chen, Hau-Jie Yau, Christina Hatch, Ikue Kusumoto-Yoshida, Saemi L Cho,Woody F Hopf and Antonello Bonci .  Rescuing cocaine-induced prefrontal cortex hypoactivity prevents compulsive cocaine seeking. .  Nature496 ( 7445 ) 359 - 362   2013.4Rescuing cocaine-induced prefrontal cortex hypoactivity prevents compulsive cocaine seeking.Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Misa Yoshimoto, Ikue Yoshida and Kenju Miki .  Functional role of diverse changes in sympathetic nerve activity in regulating arterial pressure during REM sleep. .  Sleep34   1093 - 1101   2011.12Functional role of diverse changes in sympathetic nerve activity in regulating arterial pressure during REM sleep.Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Hiroyuki Manabe1, Ikue Kusumoto-Yoshida1, Mizuho Ota, and Kensaku Mori .  Olfactory cortex generates synchronized top-down inputs to the olfactory bulb during slow-wave sleep .  Journal of Neuroscience31   8123 - 8133   2011.6Olfactory cortex generates synchronized top-down inputs to the olfactory bulb during slow-wave sleepReviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Ikue Yoshida and Kensaku Mori .  Odorant category profile selectivity of olfactory cortex neurons. .  Journal of Neuroscience27   9105 - 9114   2007.9Odorant category profile selectivity of olfactory cortex neurons.Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

▼display all

MISC

  • 中枢と末梢を結びつける神経科学的アプローチー脳と体から「こころ」を探る

    楠本-吉田 郁恵

    Annual Review 神経2017   2017.1

     More details

    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media)  

  • オプトジェネティクスを用いた自律神経機能を制御する神経回路の研究 Reviewed

    楠本-吉田郁恵、生駒葉子、桑木共之

    自律神経   2015.12

     More details

    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

  • 脳における匂い感覚地図

    五十嵐啓、吉田郁恵、森憲作

    生体の科学   58 ( 4 )   300 - 307   2007.8

     More details

    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

Presentations

  • Ikue Kusumoto-Yoshida   Cortical and hypothalamic cooperation in the control of appetite  

    2023.3 

     More details

    Event date: 2023.3

    Language:English   Presentation type:Symposium, workshop panel (public)  

    Country:Japan  

  • 植田 紘貴, 菅 真有, 八木 孝和, 楠本 郁恵, 柏谷 英樹, 桑木 共之, 宮脇 正一   唾液分泌と嚥下の調節機構における内臓感覚の役割  

    日本生理学雑誌  2017.2  (一社)日本生理学会

Research Projects

  • 鼻腔炎症に起因する脳腸連関の変動及び摂食行動の変化

    2021.7

    三島海雲記念財団  共同研究 

  • 島皮質と食欲関連視床下部神経細胞群による摂食行動調節機構の解析

    2021.4 - 2024.3

    科学研究費補助金  基盤研究(C)

      More details

    Authorship:Principal investigator 

  • 島皮質が及ぼす餌予測行動発現の重要出力回路

    2016.4 - 2018.3

    科学研究費補助金  若手研究(B)

  • マウスの空腹状態依存的な食欲形成神経回路機構

    2016.4 - 2017.4

    民間財団等  上原記念生命科学財団 

      More details

    Grant type:Competitive

  • 餌予測信号に対する動物の行動反応に与えるオレキシンニューロンの影響

    2016.2 - 2017.2

    民間財団等  児玉記念基礎医学研究助成基金 

      More details

    Grant type:Competitive

  • からだと心を結ぶ中核としての島皮質の食欲調節機構解明

    2016.1 - 2018.1

    民間財団等  光科学技術研究振興財団 

      More details

    Grant type:Competitive

  • 加齢による微量栄養素知覚変化に果たす島皮質での情報処理の役割

    2015.9 - 2016.9

    民間財団等  山田養蜂場 みつばち研究助成基金 

      More details

    Grant type:Competitive

  • 大脳皮質が調節する摂食行動に対するオレキシンの役割

    2014.4 - 2016.3

    科学研究費補助金  若手研究(B)

▼display all