-
Takasaki I, Nakamura K, Shimodaira A, Watanabe A, Du Nguyen H, Okada T, Toyooka N, Miyata A, Kurihara T
.
The novel small-molecule antagonist of PAC1 receptor attenuates formalin-induced inflammatory pain behaviors in mice.
.
J Pharmacol Sci.139
129
-
32
2018年12月査読
-
Kambe Y, Yokai M, Takasaki I, Kurihara T
.
Spinal astrocyte-neuron lactate shuttle contributes to the PACAP/PAC1 receptor-induced nociceptive behaviors.
.
bioRxiv
2018年5月
-
Takasaki I, Watanabe A, Yokai M, Watanabe Y, Hayakawa, D, Nagashima, R, Fukuchi, M, Okada, T, Toyooka, N, Miyata, A, Gouda H, Kurihara T
.
In silico screening identified novel small-molecule antagonists of PAC1 receptor.
.
Journal of Pharmacology and Experimental Therapeutics
2018年査読
-
Aizawa F, Ogaki Y, Kyoya N, Nishinaka T, Nakamoto K, Kurihara T, Hirasawa A, Miyata A, Tokuyama S.
.
The Deletion of GPR40/FFAR1 Signaling Damages Maternal Care and Emotional Function in Female Mice.
.
Biol Pharm Bull.40
(
8
)
1255
-
1259
2017年8月査読
-
Nakamoto K, Aizawa F, Miyagi K, Yamashita T, Mankura M, Koyama Y, Kasuya F, Hirasawa A, Kurihara T, Miyata A, Tokuyama S.
.
Dysfunctional GPR40/FFAR1 signaling exacerbates pain behavior in mice.
.
PLoS One
2017年7月査読
-
Yuki N, Chan AC, Wong AHY, Inoue T, Yokai M, Kurihara T, Devaux JJ, Wilder-Smith E.
.
Acute painful autoimmune neuropathy: A variant of Guillain-Barré syndrome. Muscle Nerve.
.
Muscle Nerve
2017年7月査読
-
Fuka Aizawa, Takashi Nishinaka, Takuya Yamashita, Kazuo Nakamoto, Takashi Kurihara, Akira Hirasawa, Fumiyo Kasuya, Atsuro Miyata, Shogo Tokuyama.
.
GPR40/FFAR1 deficient mice increase noradrenaline levels in the brain and exhibit abnormal behavior.
.
Journal of Pharmacological Sciences132
249
-
254
2016年11月査読
-
Yokai, M., Kurihara, T. & Miyata, A.
.
Spinal astrocytic activation contributes to both induction and maintenance of pituitary adenylate cyclase-activating polypeptide type 1 receptor-induced long-lasting mechanical allodynia in mice.
.
Molecular Pain
2016年5月査読
-
Ohnou, T., Yokai, M., Kurihara, T., Hasegawa-Moriyama, M., Shimizu, T., Kanmura, Y. & Miyata, A.
.
Pituitary adenylate cyclase-activating polypeptide type 1 receptor signaling evokes long-lasting nociceptive behaviors through the activation of spinal astrocytes in mice.
.
Journal of Pharmacological Sciences
2016年2月査読
-
Karki P., Kurihara T., Nakamachi T., Watanabe J., Asada T., Oyoshi T., Shioda S., Yoshimura M., Arita K., Miyata A.
.
Attenuation of inflammatory and neuropathic pain behaviors in mice through activation of free fatty acid receptor GPR40.
.
Molecular Pain11
6-
2015年2月査読
-
Kurihara, T., Sakurai, E., Toyomoto, M., Kii, I., Kawamoto, D., Asada, T., Tanabe, T., Yoshimura, M., Hagiwara, M. & Miyata, A.
.
Alleviation of behavioral hypersensitivity in mouse models of inflammatory pain with two structurally different casein kinase 1 (CK1) inhibitors.
.
Molecular Pain10
17
2014年3月査読
-
Hanada, T., Kurihara, T., Tokudome, M., Tokimura, H., Arita, K. & Miyata, A.
.
Development and pharmacological verification of a new mouse model of central post-stroke pain.
.
Neurosci. Res.78
72
-
80
2014年1月査読
-
Miura, A., Kambe, Y., Inoue, K., Tatsukawa, H., Kurihara, T., Griffin, M., Kojima, S. & Miyata, A.
.
Pituitary adenylate cyclase-activating polypeptide type 1 receptor (PAC1) gene is suppressed by transglutaminase 2 activation.
.
Journal of Biological Chemistry288
32720
-
32730
2013年11月査読
-
Miura, A., Odahara, N., Tominaga, A., Inoue, K., Kambe, Y., Kurihara, T. & Miyata, A.
.
Regulatory mechanism of PAC1 gene expression via Sp1 by nerve growth factor in PC12 cells.
.
FEBS Lett586
1731
-
1735
2012年1月査読
-
Kondo, D., Saegusa, H., Yabe, R., Takasaki, I., Kurihara, T., Zong, S., Tanabe, T.
.
Peripheral-type benzodiazepine receptor antagonistis effective in relieving neuropathic pain.
.
J. Pharmacol. Sci.110
55
-
63
2009年査読
-
Sakurai, E., Kurihara, T., Kouchi, K., Saegusa, H., Zong, S., Tanabe, T.
.
Upregulation of casein kinase 1ε in dorsal root ganglia and spinal cord after mouse spinal nerve injury contributes to neuropathic pain.
.
Mol. Pain5
74
2009年査読
-
Kondo, D., Yabe, R., Kurihara, T., Saegusa, H., Zong, S. , Tanabe, T.
.
Progesteron receptor anatagonist is effective in relieving neuropathic pain.
.
Eur. J. Pharmacol.541
44
-
48
2006年査読
-
Takasaki, I., Kurihara, T., Saegusa, H., Zong, S., Tanabe, T.
.
Effects of glucocorticoid receptor antagonists on allodynia and hyperalgesia in mouse model of neuropathic pain.
.
Eur. J. Pharmacol.524
80
-
83
2005年査読
-
Yokoyama, K., Kurihara, T., Saegusa, H., Zong, S., Makita, K., Tanabe, T.
.
Blocking the R-type (Cav2.3) Ca2+ channel enhanced morphine analgesia and reduced morphine tolerance.
.
Eur. J. Neurosci.20
3516
-
3519
2004年査読
-
Kurihara T., Nonaka, T. , Tanabe, T.
.
Acetic acid-conditioning stimulus induces long-lasting antinociception of somatic inflammatory pain.
.
Pharmacol. Biochem. Behavior74
841
-
849
2003年査読
-
Yokoyama, K., Kurihara, T., Makita, K. , Tanabe, T.
.
Plastic change of N-type Ca channel expression after preconditioning is responsible for prostaglandin E2-induced long-lasting allodynia.
.
Anesthesiology99
1364
-
1370
2003年査読
-
Abe M., Kurihara T., Han, W., Shinomiya, K. , Tanabe, T.
.
Changes in expression of voltage-dependent ion channel subunits in dorsal root ganglia of rats with radicular injury and pain.
.
Spine27
(
4
)
1517
-
1525
2002年査読
-
Sakashita, Y., Kurihara, T., Uchida, D., Tastuno, I., Yamamoto, T.
.
Involvement of PACAP receptor in primary afferent fibre-evoked responses of ventral roots in the neonatal rat spinal cord.
.
British Journal of Pharmacology132
1769
-
1776
2001年査読
-
Ogasawara, M., Kurihara, T., Hu, Q. , Tanabe, T.
.
Characterization of acute somatosensory pain transmission in P/Q-type Ca2+ channel mutant mice, leaner.
.
FEBS Lett.508
181
-
186
2001年査読
-
Saegusa, H., Kurihara, T., Zong, S., Kazuno, A., Matsuda, Y., Nonaka, T., Han, W., Toriyama, H., Tanabe, T. (H. Saegusa and T. Kurihara contributed equally to this work)
.
Suppression of inflammatory and neuropathic pain symptoms in mice lacking the N-type Ca2+ channel.
.
The EMBO Journal20
2349
-
2356
2001年査読
-
Saegusa, H., Kurihara, T., Zong, S., Minowa, O., Kazuno, A., Han, W., Matsuda, Y., Yamanaka, H., Osanai, M., Noda, T., Tanabe, T.
.
Altered pain responses in mice lacking α1E subunit of the voltage-dependent Ca2+ channel.
.
Proc. Natl. Acad. Sci. USA97
6132
-
6137
2000年査読
-
Kurihara, T., Yoshioka, K.
.
The excitatory and inhibitory modulation of primary afferent fibre-evoked responses of ventral roots in the neonatal rat spinal cord exerted by nitric oxide.
.
British Journal of Pharmacology118
1743
-
1753
1996年査読
-
Otsuka, M., Yoshioka, K., Yanagisawa, M., Suzuki, H., Zhao, F-Y., Guo, J.-Z., Hosoki, R. , Kurihara, T.
.
Use of NK1 receptor antagonists in the exploration of physiological functions of substance P and neurokinin A.
.
Canadian Journal of Physiology and Pharmacology73
903
-
907
1995年査読
-
Kurihara, T., Yoshioka,K., Otsuka, M.
.
Tachykininergic slow depolarization of motoneurones evoked by descending fibres in the neonatal rat spinal cord.
.
The Journal of Physiology (London)485
787
-
796
1995年査読
-
Suzuki, H., Yoshioka, K., Yanagisawa, M., Urayama, O., Kurihara, T., Hosoki, R., Saito, K., Otsuka, M.
.
Involvement of enzymatic degradation in the inactivation of tachykinin neurotransmitters in neonatal rat spinal cord.
.
British Journal of Pharmacology113
310
-
316
1994年査読
-
Kurihara, T., Suzuki, H., Yanagisawa, M., Yoshioka, K.
.
Muscarinic excitatory and inhibitory mechanisms involved in afferent fibre-evoked depolarization of motoneurones in the neonatal rat spinal cord.
.
British Journal of Pharmacology110
61
-
70
1993年査読
-
Yanagisawa, M., Yoshioka, K., Kurihara, T., Saito, K., Seno, N., Suzuki, H., Hosoki, R. , Otsuka, M.
.
Enzymatic inactivation of tachykinin neurotransmitters in the isolated spinal cord of the newborn rat.
.
Neuroscience Research15
289
-
292
1992年査読
