General Information

写真a

Shingo Maeda


Position

Associate Professor

Research Fields, Keywords

osteoblast/chondrocyte differentiation, BMP, TGF-beta

Profile

Roles of TGF-beta family signaling in osteoblast/chondrocyte differentiation.
Roles of TGF-beta family signaling in pathogenesis of osteoarthritis or ossification of posterior longitudinal ligament of spine.

Graduating School 【 display / non-display

  • Nagasaki University, Faculty of Medicine

    University, 1994.03, Graduated, JAPAN

Graduate School 【 display / non-display

  • Kagoshima University, Graduate School, Division of Medicine

    Doctor's Course, 2001.03, Completed, JAPAN

Degree 【 display / non-display

  • Doctor (Medicine), Orthopaedic surgery, Kagoshima University, Coursework, 2001.03

Academic Career at Kagoshima Univ. 【 display / non-display

  • Kagoshima University Research Field in Medicine and Health Sciences, Medical and Dental Sciences Area Graduate School of Medical and Dental Sciences Contribution Course Medical Joint Materials(KYOCERA Medical), Associate Professor, 2009.04 -

External Career 【 display / non-display

  • Institute of Human Genetics (Jean-Marc Lalouel Lab.), University of Utah, U.S.A., , 1997.04 - 1997.12

Field of expertise (Grants-in-aid for Scientific Research classification) 【 display / non-display

  • Orthopaedic surgery

 

Papers 【 display / non-display

  • English, PEG10 counteracts signaling pathways of TGF-β and BMP to regulate growth, motility and invasion of SW1353 chondrosarcoma cells, J Bone Miner Metab, 2018.08, Yahiro Y, Maeda S, Shinohara N, Jokoji G, Sakuma D, Setoguchi T, Ishidou Y, Nagano S, Komiya S, Taniguchi N.

    DOI:10.1007/s00774-018-0946-8, Research paper (scientific journal), Peer reviewed, Multiple Authorship

  • English, TGF-β signalling and PEG10 are mutually exclusive and inhibitory in chondrosarcoma cells, Scientific Reports, vol.7 (1) (pp.13494 - ) , 2017.10, Shinohara N, Maeda S, Yahiro Y, Sakuma D, Matsuyama K, Imamura K, Kawamura I, Setoguchi T, Ishidou Y, Nagano S, Komiya S.

    DOI:10.1038/s41598-017-13994-w, Research paper (scientific journal), Peer reviewed, Multiple Authorship

  • English, Combination of Hedgehog inhibitors and standard anticancer agents synergistically prevent osteosarcoma growth, International Journal of Oncology, vol.48 (1) (pp.235 - 242) , 2016.01, Yoshinobu Saitoh, Takao Setoguchi, Masahito Nagata, Arisa Tsuru, Shunsuke Nakamura, Satoshi Nagano, Yasuhiro Ishidou, Hiroko Nagao-Kitamoto, Masahiro Yokouchi, Shingo Maeda, Akihide Tanimoto, Tatsuhiko Furukawa, Setsuro Komiya

    DOI:10.3892/ijo.2015.3236., Research paper (scientific journal), Peer reviewed, Multiple Authorship

  • English, Hairy/enhancer-of-split related with YRPW motif protein 1 promotes osteosarcoma metastasis via matrix metallopeptidase 9 expression., Br J Cancer, vol.112 (pp.1232 - 1240) , 2015.03, Tsuru A, Setoguchi T, Matsunoshita Y, Nagao-Kitamoto H, Nagano S, Yokouchi M, Maeda S, Ishidou Y, Yamamoto T, Komiya S

    Research paper (scientific journal), Peer reviewed, Multiple Authorship

  • English, GLI2 is a novel therapeutic target for metastasis of osteosarcoma, Int J Cancer, vol.136 (6) (pp.1276 - 1284) , 2015.03, Nagao-Kitamoto H, Nagata M, Nagano S, Kitamoto S, Ishidou Y, Yamamoto T, Nakamura S, Tsuru A, Abematsu M, Fujimoto Y, Yokouchi M, Kitajima S, Yoshioka T, Maeda S, Yonezawa S, Komiya S, Setoguchi T.

    Research paper (scientific journal), Peer reviewed, Multiple Authorship

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Books 【 display / non-display

  • English, Smad Transcriptional Co-activators and Co-repressors., PROTEINS AND CELL REGULATION VOLUME 5, Smad Signal Transduction: Smads in Proliferation, Differentiation and Disease.P. ten Dijke and C.-H. Heldin (eds.)・Springer, 2006, Kohei Miyazono, Shingo Maeda, Takeshi Imamura

    Scholarly Book, Multiple Authorship

Review Papers 【 display / non-display

  • English, An impact of CCN2-BMP-2 complex upon chondrocyte biology: evoking a signalling pathway bypasses ERK and Smads-, J Biochem, vol.150 (3) (pp.219 - 221) , 2011.09, Shingo Maeda

    Introduction and explanation (scientific journal), Single Author

  • English, BMP receptor signaling: transcriptional targets, regulation of signals, and signaling cross-talk., Cytokine Growth Factor Rev, vol.16 (pp.251 - 263) , 2005, Miyazono K, Maeda S, Imamura T.

    Introduction and explanation (scientific journal), Multiple Authorship