Updated on 2021/06/03

写真a

 
SETOYAMA Kentaro
 
Organization
Research Field in Cooperation, Integrated Arts and Sciences Area Center for Advanced Science Research and Promotion Research Support Center, Institute for Research Promotion Institute of Laboratory Animal Sciences Associate Professor
Title
Associate Professor

Degree

  • 博士(獣医学) ( 2006.9   山口大学 )

Research Interests

  • 心疾患モデル動物 再生 移植免疫

Research History

  • Kagoshima University   Associate Professor

    2012.4

  • Kagoshima University

    2003.10

Professional Memberships

  • 九州実験動物研究会

    2015.10

  • 日本実験動物学会

    2015.10

  • 日本獣医学会

    2013.4

 

Papers

  • Kiyoshi Kikuchi, Kentaro Setoyama, Seiya Takada et al .  E8002 Inhibits Peripheral Nerve Adhesion by Enhancing Fibrinolysis of l-Ascorbic Acid in a Rat Sciatic Nerve Model .  International Journal of Molecular Sciences21 ( 11 )   2020.6E8002 Inhibits Peripheral Nerve Adhesion by Enhancing Fibrinolysis of l-Ascorbic Acid in a Rat Sciatic Nerve ModelReviewed

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  • Kiyoshi Kikuchi, Kentaro Setoyama, et al. .  Uric acid enhances alteplase-mediated thrombolysis as an antioxidant. .  Scientific Reports26 ( 8 )   2018.10Uric acid enhances alteplase-mediated thrombolysis as an antioxidant.Reviewed

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  • Kiyoshi Kikuchi, Kentaro Setoyama, Takuto Terashi et al .  Application of a Novel Anti-Adhesive Membrane, E8002, in a Rat Laminectomy Model. .  International Journal of Molecular Sciences   2018.5Application of a Novel Anti-Adhesive Membrane, E8002, in a Rat Laminectomy Model.Reviewed

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  • 上村 利也, 古川 絢賀, 瀬戸山 健太郎, 町田 登 .  心室中隔の菲薄化が目立った拡張型心筋症の犬の1例 .  動物の循環器51 ( 2 ) 89 - 92   2018

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    Publisher:獣医循環器研究会  

    拡張型心筋症(DCM)は,心筋収縮能の低下による心室の収縮機能障害と内腔の拡張を特徴とし,重篤な心不全をきたす進行性かつ予後不良の心筋疾患である。DCMの原因因子としては,遺伝的因子,栄養欠乏,代謝異常,免疫異常,感染性疾患,薬物誘発性,中毒誘発性,頻拍誘発性の心筋運動低下などが挙げられている。心エコー図検査では,Mモード法で計測した左室収縮末期径(LVDs)と左室拡張末期径(LVDd)は増加し,左室内径短縮率(FS)が低下する。左室壁の運動性は広範囲に低下し,左室自由壁と心室中隔の壁厚はおおむね均一に減少するのが一般的である。今回,心エコー図検査にて心室中隔の菲薄化が特に目立った。珍しいパターンの犬のDCM症例に遭遇した。

    DOI: 10.11276/jsvc.51.89

  • Kikuchi K, Setoyama K, Kawahara KI et al .  Edaravone, a Synthetic Free Radical Scavenger, Enhances Alteplase-Mediated Thrombolysis. .  Oxidative Medicine and Cellular Longevity   2017.11Edaravone, a Synthetic Free Radical Scavenger, Enhances Alteplase-Mediated Thrombolysis.Reviewed

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  • Kyle A. Soltys, Kentaro Setoyama, Edgar N. Tafaleng, et al .  Host conditioning and rejection monitoring in hepatocyte transplantation in humans .  Journal of Hepatology66 ( 5 ) 987 - 1000   2017.5Host conditioning and rejection monitoring in hepatocyte transplantation in humansReviewed

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  • Nishikawa T, Bell A, Brooks JM, Setoyama K, Melis M, Han B, Fukumitsu K, Handa K, Tian J, Kaestner KH, Vodovotz Y, Locker J, Soto-Gutierrez A, Fox IJ. .  Resetting the transcription factor network reverses terminal chronic hepatic failure .  J Clin Invest125 ( 4 ) 1533 - 1544   2015.4Resetting the transcription factor network reverses terminal chronic hepatic failureReviewed

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  • Miura K, Sahara H, Sekijima M, Kawai A, Waki S, Nishimura H, Setoyama K, Clayman ES, Shimizu A, Yamada K .  Protective effect of neutralization of the extracellular high-mobility group box 1 on renal ischemia-reperfusion injury in miniature swine .  Transplantation98 ( 9 ) 937 - 943   2014.11Protective effect of neutralization of the extracellular high-mobility group box 1 on renal ischemia-reperfusion injury in miniature swineReviewed

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  • Setoyama K, Yannam GR, Han B, Yamamoto T, Ito R, Brooks JM, Guzman-Lepe J, Galambos C, Fong JV, Deutsch M, Quader MA, Yamanouchi K, Kabarriti R, Mehta K, Soto-Gutierrez A, Roy-Chowdhury J, Locker J, Abe M, Enke CA, Baranowska-Kortylewicz J, Solberg TD, Guha C, Fox IJ. .  A non-human primate model of human radiation-induced venocclusive liver disease and hepatocyte injury .  International Journal of Radiation Oncology Biology and Physics (in press)   2013A non-human primate model of human radiation-induced venocclusive liver disease and hepatocyte injuryReviewed

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  • Hamada N, Nishi Y, Tajiri Y, Setoyama K, Kamimura R, Miyahara K, Nuruki N, Hosoda H, Kangawa K, Kojima M .  Disrupted Regulation of Ghrelin Production Under Antihypertensive Treatment in Spontaneously Hypertensive Rats. .  Circulation Journal   2012.3Disrupted Regulation of Ghrelin Production Under Antihypertensive Treatment in Spontaneously Hypertensive Rats.Reviewed

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  • Oku M, Okumi M, Shimizu A, Sahara H, Setoyama K, Nishimura H, Sada M, Scalea J, Ido A, Sachs DH, Tsubouchi H, Yamada K .  Hepatocyte growth factor sustains T regulatory cells and prolongs the survival of kidney allografts in major histocompatibility complex-inbred CLAWN-miniature swine. .  Transplantation   2012.1Hepatocyte growth factor sustains T regulatory cells and prolongs the survival of kidney allografts in major histocompatibility complex-inbred CLAWN-miniature swine.Reviewed

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  • Hiramine K, Sata N, Ido A, Kamimura R, Setoyama K, Arai K, Nuruki N, Tanaka Y, Uto H, Tsubouchi H .  Hepatocyte growth factor improves the survival of rats with pulmonary arterial hypertension via the amelioration of pulmonary hemodynamics. .  International Journal of Molecular Medicine   2011.4Hepatocyte growth factor improves the survival of rats with pulmonary arterial hypertension via the amelioration of pulmonary hemodynamics.Reviewed

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  • Sahara H, Shimizu A, Setoyama K, Oku M, Okumi M, Nishimura H, Oriyanhan W, Tasaki M, Scalea J, Wada H, Bando T, Date H, Yamada K .  Beneficial effects of perioperative low-dose inhaled carbon monoxide on pulmonary allograft survival in MHC-inbred CLAWN miniature swine. .  Transplantation   2010.12Beneficial effects of perioperative low-dose inhaled carbon monoxide on pulmonary allograft survival in MHC-inbred CLAWN miniature swine.Reviewed

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  • Sahara H, Shimizu A, Setoyama K, Okumi M, Oku M, Samelson-Jones E, Yamada K. .  Carbon monoxide reduces pulmonary ischemia-reperfusion injury in miniature swine. .  Journal of Thoracic Cardiovascular Surgery   2010.6Carbon monoxide reduces pulmonary ischemia-reperfusion injury in miniature swine.Reviewed

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  • Ko-ichi Kawahara, Kentaro Setoyama, Kiyoshi Kikuchi, Kamal Krishna Biswas, Ryozo Kamimura, Masahiro Iwata, Takashi Ito, Yoko Morimoto, Teruto Hashiguchi Sonshin Takao, Ikuro Maruyama .  HMGB1 release in co-cultures of porcine endothelial and human T cells .  Xenotransplantation14 ( 6 ) 636 - 641   2007.11HMGB1 release in co-cultures of porcine endothelial and human T cellsReviewed

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  • Akira Yabuki, Ryozo Kamimura, Kentaro Setoyama, Junichi Tottori,Mitsuharu Matsumoto, Shusaku Suzuki .  Skin morphology of the Clawn miniature pig .  Experimental Animals56 ( 5 ) 369 - 373   2007.10Skin morphology of the Clawn miniature pigReviewed

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  • Ryozo Kamimura, Kentaro Setoyama, Akira Yabuki, Junichi Tottori, Syusaku Suzuki .  Characteristics and Gender Differences Pulmonary Hemodynamics in Clawn Miniature Pigs .  Experimental Animals56 ( 5 ) 375 - 378   2007.10Characteristics and Gender Differences Pulmonary Hemodynamics in Clawn Miniature PigsReviewed

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  • Kentaro Setoyama, Ryozo Kamimura, Makoto Fujiki, Kazuhiro Misumi, Kenkichi Miyahara, Hiroshi Sakamoto .  Effects of Olprinone on Myocardial Ischemia-Reperfusion Injury in Dogs. .  J Vet Med Sci68 ( 8 ) 865 - 868   2006.8Effects of Olprinone on Myocardial Ischemia-Reperfusion Injury in Dogs.Reviewed

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  • 上村亮三、御船弘治、矢吹映、瀬戸山健太郎、管野正美、鳥取潤一、鈴木秀作 .  低体温Clawnミニブタの血行動態とANP動態 .  九州実験動物雑誌21   21 - 25   2005.11低体温Clawnミニブタの血行動態とANP動態Reviewed

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  • Takuya Yamashita, Yukinori Moriyama, Naoyuki Sata, Naokazu Hamada, Takashi Horinouchi, Shigeru Amitani, Kenkichi Miyahara, Kentaro Setoyama, Kazuhiro Misumi, Hiroshi Sakamoto .  Discrepancy between Doppler and Catheter Measurements of Pressure Gradients across Small-size Prosthetic Valve .  Jpn J Thorac Cardiovasc Surg53   64 - 68   2005.2Discrepancy between Doppler and Catheter Measurements of Pressure Gradients across Small-size Prosthetic ValveReviewed

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  • 瀬戸山健太郎、上村亮三、藤木誠、三角一浩、坂本紘 .  塩酸オルプリノンが低体温-体外循環離脱時にビーグル犬の血行動態におよぼす影響について .  九州実験動物雑誌20   15 - 19   2004.11塩酸オルプリノンが低体温-体外循環離脱時にビーグル犬の血行動態におよぼす影響についてReviewed

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  • Takashi Horinouchi, Naoyuki Sata, Naokazu Hamada, Shigeru Amitani, Kenkichi Miyahara, Norihito Nuruki, Yasuhiro Tanaka, Kentaro Setoyama, Kazuhiro Misumi, and Hiroshi Sakamoto .  Assessment of Optimal Atrioventricular Delay Using Doppler Index in Atrioventricular Sequential Pacing .  Jpn Coll Angiol44   103 - 107   2004.3Assessment of Optimal Atrioventricular Delay Using Doppler Index in Atrioventricular Sequential PacingReviewed

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  • Kentaro Setoyama, Takeshi Shinzato, Kazuhiro Misumi, Makoto Fujiki, Hiroshi Sakamoto .  Effects of propofol-sevoflurane anesthesia on the maternal and fetal hemodynamics blood gases, and uterine activity in pregnant goats. .  J Vet Med Sci65 ( 10 ) 1075 - 1081   2003.10Effects of propofol-sevoflurane anesthesia on the maternal and fetal hemodynamics blood gases, and uterine activity in pregnant goats.Reviewed

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  • N. Miura, M. Fujiki, K. Misumi, K. Setoyama, K. Takegawa, T. Takahashi, K. Miyahara, H. Sakamoto .  Successful use of an acceleration rate response pacemaker with a transvenous steroid-eluting screw-in lead for third-degree atrioventricular block in a labrador retriever. .  J Vet Med Sci65 ( 10 ) 1101 - 1105   2003.10Successful use of an acceleration rate response pacemaker with a transvenous steroid-eluting screw-in lead for third-degree atrioventricular block in a labrador retriever.Reviewed

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  • Kentaro Setoyama, Hiromi Ota, Naoki Miura, Makoto Fujiki, Kazuhiro Misumi, Hiroshi Sakamoto .  Effects of milrinone on hemodynamics and regional blood flow in the hypoxic dog. .  J Vet Med Sci64 ( 6 ) 499 - 503   2002.6Effects of milrinone on hemodynamics and regional blood flow in the hypoxic dog.Reviewed

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Books

  • Liver and Hepatocyte Xenotransplantation

    Jiffery L Platt, Kentaro Setoyama, Ira J Fox( Role: Joint author)

    Transplantation of the Liver 3rd edition, ELSEVIER SAUNDERS  2015.1 

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    Language:English Book type:Scholarly book

Presentations

  • Setoyama Kentaro   Anesthesia of Swine  

    2019.5 

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    Event date: 2019.5

  • 佐原 寿史, 岩永 健裕, 瀬戸山 健太郎, 関島 光裕, 室川 剛廣, 有吉 勇一, 市成 ゆりか, 山田 和彦   実験動物としてのブタ-最新の応用例から動物福祉まで- MHC確立クラウン系ミニブタを用いた前臨床同種・異種移植研究の実際  

    第160回日本獣医学会学術集会  2017.8  (公社)日本獣医学会

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    Event date: 2017.9

  • 上村 利也, 古川 綾賀, 中村 麗菜, 吉井 裕太, 瀬戸山 健太郎   閉塞性肥大型心筋症が疑われた犬の1例  

    第94回日本獣医麻酔外科学会  2017.6  (一社)日本獣医麻酔外科学会

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    Event date: 2017.6

  • Govardhana R. Yannam, Bing Han, Kentaro Setoyama,Toshiyuki Yamamoto, Ryotaro Ito, Jenna M. Brooks, Jorge Guz-man-Lepe, Csaba Galambos, Jason V. Fong, Melvin Deutsch,Mubina A. Quader, Kosho Yamanouchi, Keyur Mehta, Ale-jandro Soto-Gutierrez , Jayanta Roy-Chowdhury , JosephLocker, Michio Abe, Charles A. Enke, Janina Baranowska-Kortylewicz, Timothy D. Solberg, Chandan Guha, Ira J.Fox   Tolerable limits to whole liver irradiation in non-humanprimates   International conference

    63rd Annual Meeting of the American Association for the Study of Liver Diseases  63rd Annual Meeting of the American Association for the Study of Liver Diseases

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    Event date: 2012.11

    Language:English  

    Venue:アメリカ合衆国  

    国際学会

  • Kentaro Setoyama, Ryotaro Ito, Jason V Fong, Bing Han, Masaki Nagaya, Mark Ross, Ken Fukumitsu, Roberto Gramignoli, Shawn Rosensteel, Stephen C Strom, Donna Beer Stolz, Mubina Quader, Melvin Deutsch, Kevin Baskin, Jayanta Roy Chowdhury, Chandan Guha, Alejandro Soto-Gutierrez, Ira J Fox   10-15% Donor Cell Liver Repopulation in Non-Human Primates by Low Dose Directed (Right Lobe) Radiation Therapy: A Preclinical Study   International conference

    62nd Annual Meeting of the American Association for the Study of Liver Diseases  62nd Annual Meeting of the American Association for the Study of Liver Diseases

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    Event date: 2011.11

    Language:English  

    Venue:アメリカ合衆国  

    国際学会

  • Tasaki M, Sahara H, Okitsu T, Oku M, Nishimura H, Sekijima M, Setoyama K, Shimizu A, Yamada K   Prolongation of xenoegeneic islet function using an HGF-based immunosuppressive regimen in a CLAWN miniature swine-to-cynomologous monkey model   International conference

    Prolongation of xenoegeneic islet function using an HGF-based immunosuppressive regimen in a CLAWN miniature swine-to-cynomologous monkey model  Prolongation of xenoegeneic islet function using an HGF-based immunosuppressive regimen in a CLAWN miniature swine-to-cynomologous monkey model

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    Event date: 2011.10

    Language:English  

    Venue:アメリカ合衆国  

    国際学会

  • Sahara H, Nagashima H, Sekijima M, Tasaki M, Setoyama K, Matsunari H, Nakano K, Date H, Shimizu A, Yamada K   Sahara H, Nagashima H, Sekijima M, Tasaki M, Setoyama K, Matsunari H, Nakano K, Date H, Shimizu A, Yamada K   International conference

    CTS (Cell Transplant Society) -IXA (International Xenotransplantation Association) 2011 Joint Congress.  CTS (Cell Transplant Society) -IXA (International Xenotransplantation Association) 2011 Joint Congress.

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    Event date: 2011.10

    Language:English  

    Venue:アメリカ合衆国  

    国際学会

  • Sahara H, Shimizu A, Setoyama K, Oku M, Nishimura H, Yamada K   Protective effect of neutralization of the extracellular high-mobility group box-1 on pulmonary ischemia-reperfusion injury in miniature swine.   International conference

    12th Congress of the Asian Society of Transplantation  12th Congress of the Asian Society of Transplantation

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    Event date: 2011.9

    Language:English  

    Venue:韓国  

    国際学会

  • Sahara H, Shimizu A, Tasaki M, Sekijima M, Oku M, Nishimura H, Iwamoto E, Setoyama K, Yamada K   Sahara H, Shimizu A, Tasaki M, Sekijima M, Oku M, Nishimura H, Iwamoto E, Setoyama K, Yamada K   International conference

    12th Congress of the Asian Society of Transplantation  12th Congress of the Asian Society of Transplantation

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    Event date: 2011.9

    Language:English  

    Venue:韓国  

    国際学会

  • Sahara H, Shimizu A, Tasaki M, Oku M, Nishimura H, Setoyama K, Yamada K   Treatment of only the donor with carbon monoxide (CO) prolongs pulmonary allograft survival in miniature swine   International conference

    International Society for Heart and Lung Transplantation 31st Annual Meeting  International Society for Heart and Lung Transplantation 31st Annual Meeting

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    Event date: 2011.4

    Language:English  

    Venue:アメリカ合衆国  

    国際学会

  • 佐原寿史、屋 万栄、田﨑正行、西村博昭、瀬戸山健太郎、Oriyanhan Wunimenghe、奥見雅由、清水 章、山田和彦   MHC確立クラウン系ミニブタ大動物同種移植モデルを用いた移植免疫学的機序にに基づく新たな治療戦略の確立  

    第46回日本移植学会総会  第46回日本移植学会総会

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    Event date: 2010.10

    Language:Japanese  

    Venue:大阪  

    国内学会

  • 佐原寿史、瀬戸山健太郎、西村博昭、W. Oriyanhan、屋 万栄、奥見雅由、清水 章、山田和彦   「シンポジウム心・肺移植における長期生着阻害因子とその対策」移植肺生着阻害因子としてのMHC差異・虚血再灌流障害(IRI)及び一酸化炭素(CO)吸入を用いた拒絶抑制効果-MHC確立ミニブタ肺移植モデルによる検討   International conference

    第45回日本移植学会総会  第45回日本移植学会総会

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    Event date: 2009.9

    Language:English  

    Venue:東京  

    国際学会

  • Sahara H, Oku M, Okumi M, Setoyama K, Shimizu A, Yamada K   Sahara H, Oku M, Okumi M, Setoyama K, Shimizu A, Yamada K   International conference

    International Society for Heart and Lung Transplantation 28th Annual Meeting and Scientific Sessions  International Society for Heart and Lung Transplantation 28th Annual Meeting and Scientific Sessions

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    Event date: 2009.4

    Language:English  

    Venue:フランス  

    国際学会

  • Nishimura H, Oku M, Okumi M, Sahara H, Setoyama K, Oriyanhan W, Shimizu A, Yamada K   Hepatocyte Growth Factor Prolongs Allograft Survival with Maintenance of Treg Population in MHC-inbred CLAWN Miniature Swine   International conference

    104th American Urological Association Annual Meeting  104th American Urological Association Annual Meeting

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    Event date: 2009.4

    Language:English  

    国際学会

  • 佐原寿史、奥見雅由、屋万栄、瀬戸山健太郎、上村亮三、清水章、山田和彦   MHC inbredクラウンミニブタにおけるMHC適合の相違による移植肺拒絶病変進展形式の差異  

    第43回日本移植学会総会  第43回日本移植学会総会

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    Event date: 2007.11

    Language:Japanese  

    Venue:宮城  

    国内学会

  • 奥見雅由、佐原寿史、屋万栄、瀬戸山健太郎、上村亮三、清水章、山田和彦   国産MHC inbredミニブタ同種間腎移植での慢性拒絶反応モデルの確立  

    第43会日本移植学会総会  第43会日本移植学会総会

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    Event date: 2007.11

    Language:Japanese  

    Venue:宮城  

    国内学会

  • Kiyohisa Hiramine, Naoyuki Sata, Yasuhiro Tanaka, Hirohito Tsubouchi, Kentarou Setoyama, Ryouzo Kamimura, Kou Arai, Hiroko Kariyazono, Kenkichi Miyahara   Recombinant Human Hepatocyte Growth Factor Improves Monocrotaline-Induced Pulmonary Hypertension  

    第71回日本循環器学会学術集会総会  第71回日本循環器学会学術集会総会

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    Event date: 2007.3

    Language:Japanese  

    Venue:兵庫  

    国内学会

  • Nobuyuki Murakoshi, Kentaro Yoshida, Kazuyuki Tanoue, Keisuke Kuga, Ryouzou Kamimura, Kentaro Setoyama, Yukio Sekiguchi, Iwao Yamaguchi, Kazutaka Aonuma   AAV-mediated Gene Transfer of HCN4 into Cardiac Conduction System Significantly Increases Heart Rate in the Canine Model of AV Block  

    第71回日本循環器学会学術集会総会  第71回日本循環器学会学術集会総会

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    Event date: 2007.3

    Language:Japanese  

    Venue:兵庫  

    国内学会

  • 矢吹映、上村亮三、瀬戸山健太郎、松元光春、鈴木秀作   クラウンミニブタの皮膚に関する組織学的研究  

    第24回九州実験動物研究会  第24回九州実験動物研究会

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    Event date: 2006.11

    Language:Japanese  

    Venue:山口  

    研究会

  • 瀬戸山健太郎、上村亮三、藤木誠、三角一浩、坂本紘   心筋の虚血再灌流傷害に対する塩酸オルプリノンの効果  

    第83回日本獣医循環器学会  第83回日本獣医循環器学会

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    Event date: 2005.10

    Language:Japanese  

    Venue:福岡  

    国内学会

  • 上村亮三、矢吹映、瀬戸山健太郎、松元光春、鈴木秀作   低体温モデルClawnミニブタの血行動態およびANP動態の検討  

    第138回日本獣医学会学術集会  第138回日本獣医学会学術集会

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    Event date: 2004.9

    Language:Japanese  

    Venue:北海道  

    国内学会

  • 上村亮三、瀬戸山健太郎、矢吹映、鈴木秀作   クラウンミニブタの肺動脈の分岐形態  

    第22回九州実験動物研究会  第22回九州実験動物研究会

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    Event date: 2003.11

    Language:Japanese  

    Venue:大分  

    研究会

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