American Chemical Society

2016.2

Glyco-Nanoadjuvants: Sugar Structures on Carriers of a Small Molecule TLR7 Ligand Affect Their Immunostimulatory Activities .  ACS Appl. Bio Mater.4 ( 3 ) 2732 - 2741   2021.3Reviewed International coauthorship

Akihito Baba, Masahiro Wakao, Hiroyuki Shinchi, Michael Chan, Tomoko Hayashi, Shiyin Yao, Howard B. Cottam, Dennis A.Carson, Yasuo Suda .  Synthesis and immunostimulatory activity of sugar chain-conjugated TLR7 ligands .  Bioorganic and Medicinal Chemistry Letters30 ( 3 ) 126840   2020.2Synthesis and immunostimulatory activity of sugar chain-conjugated TLR7 ligandsReviewed

Wakao Masahiro, Shinchi Hiroyuki, Baba Akihito, Chan Michael, Hayashi Tomoko, B. Cottam Howard, A. Carson Dennis, Suda Yasuo .  Synthesis and immunostimulatory activity of TLR7 ligand conjugate .  Endotoxin and Innate Immunity23 ( 0 ) 28 - 33   2020

Hiroyuki Shinchi, Tomoya Nakamura, Hayato Ota, Shoko Nishihara, Masahiro Wakao, Yasuo Suda .  Cell profiling based on sugar chain-cell binding interaction and application to typing and quality verification of cells .  ChemBioChem20 ( 14 ) 1810 - 1816   2019.7

Yamaguchi Toru, Shinchi Hiroyuki, Moroishi Toshiro, Wakao Masahiro, Hayashi Tomoko, B. Cottam Howard, A. Carson Dennis, Suda Yasuo .  Development of Toll-like receptor 7 ligand and sugar chain immobilized gold nanoparticles for vaccine adjuvant and immunotherapy .  Endotoxin and Innate Immunity22 ( 0 ) 35 - 39   2019

Kaname Muchima, Taro Todaka, Hiroyuki Shinchi, Ayaka Sato, Arisa Tazoe, Rikiya Aramaki, Yuhei Kakitsubata, Risa Yokoyama, Naomichi Arima, Masanori Baba, Masahiro Wakao, Yuji Ito, Yasuo Suda .  Development of sugar chain-binding single chain variable fragment antibody to adult T-cell leukemia cells using glyco-nanotechnology and phage display method .  J. Biochem.163 ( 4 ) 281 - 291   2018.4Reviewed

Muchima Kaname, Todaka Taro, Shinchi Hiroyuki, Sato Ayaka, Tazoe Arisa, Aramaki Rikiya, Kakitsubata Yuhei, Yokoyama Risa, Arima Naomichi, Baba Masanori, Wakao Masahiro, Ito Yuji, Suda Yasuo .  糖鎖ナノテクノロジー及びファージディスプレイ法を用いた成人T細胞白血病に対する糖鎖結合性一本鎖抗体の開発(Development of sugar chain-binding single-chain variable fragment antibody to adult T-cell leukemia cells using glyco-nanotechnology and phage display method) .  The Journal of Biochemistry163 ( 4 ) 281 - 291   2018.4糖鎖ナノテクノロジー及びファージディスプレイ法を用いた成人T細胞白血病に対する糖鎖結合性一本鎖抗体の開発(Development of sugar chain-binding single-chain variable fragment antibody to adult T-cell leukemia cells using glyco-nanotechnology and phage display method)

Oyama Shin-ya, B. Cottam Howard, A. Carson Dennis, Suda Yasuo, Wakao Masahiro, Ahmadiiveli Alast, Kakitsubata Yuhei, Yamaguchi Toru, Shinchi Hiroyuki, Chan Michael, M. Shukla Nikunj, Hayashi Tomoko .  The study on structure-activity relationship of pyrimidoindoles TLR4 ligands .  Endotoxin and Innate Immunity21 ( 0 ) 42 - 46   2018

1) Wakao, M.; Watanabe, S.; Kurahashi, Y.; Matsuo, T.; Takeuchi, M.; Ogawa, T.; Suzuki, K.; Yumino, T.; Myogadani, T.; Saito, A.; Muta, K.; Kimura M.; Kajikawa, K.; Suda, Y. .  Structure−activity relationship studies of pyrimido[5,4‑b]indoles as selective Toll-like receptor 4 ligands .  Journal of Medicinal Chemistry60 ( 22 ) 9142 - 9161   2017.10Structure−activity relationship studies of pyrimido[5,4‑b]indoles as selective Toll-like receptor 4 ligandsReviewed

1) Wakao, M.; Watanabe, S.; Kurahashi, Y.; Matsuo, T.; Takeuchi, M.; Ogawa, T.; Suzuki, K.; Yumino, T.; Myogadani, T.; Saito, A.; Muta, K.; Kimura M.; Kajikawa, K.; Suda, Y. .  Optical Fiber-Type Sugar Chip Using Localized Surface Plasmon Resonance .  Analytical Chemistry89 ( 2 ) 1086 - 1091   2017.1Reviewed

Yuhei Kakitsubata, Rikiya Aramaki, Kyosuke Nishioka, Kyosuke, Masahiro Wakao, Yasuo Suda .  Toward the construction of dermatan sulfate (DS) partial disaccharide library: efficient synthesis of building blocks, common intermediate, and ligand conjugate of type-B DS disaccharide .  Tetrahedron Letters57 ( 10 ) 1154 - 1157   2016.3Toward the construction of dermatan sulfate (DS) partial disaccharide library: efficient synthesis of building blocks, common intermediate, and ligand conjugate of type-B DS disaccharideReviewed

Hiroyuki Shinchi, Nobuhiro Yuki, Hideharu Ishida, Koichi Hirata, Masahiro Wakao, Yasuo Suda .  Visual Detection of Human Antibodies Using Sugar Chain-Immobilized Fluorescent Nanoparticles: Application as a Point of Care Diagnostic Tool for Guillain-Barre Syndrome .  PLOS ONE10 ( 9 ) e0137966   2015.9Visual Detection of Human Antibodies Using Sugar Chain-Immobilized Fluorescent Nanoparticles: Application as a Point of Care Diagnostic Tool for Guillain-Barre SyndromeReviewed

K. Teruya, M. Wakao, M. Sato, T. Hamanaka, K. Nishizawa, Y. Funayama, Y. Sakasegawa, Y. Suda, K. Doh-Ura .  Heparinase I-specific disaccharide unit of heparin is a key structure but insufficient for exerting anti-prion activity in prion-infected cells .  Biochem. Biophys. Res. Commun.460 ( 4 ) 989 - 995   2015.5Heparinase I-specific disaccharide unit of heparin is a key structure but insufficient for exerting anti-prion activity in prion-infected cellsReviewed

K. Miyachi, M. Wakao, Y. Suda .  Syntheses of chondroitin sulfate tetrasaccharide structures containing 4,6-disulfate patterns and analysis of their interaction with glycosaminoglycan-binding protein .  Bioorg. Med. Chem. Lett. 25 ( 7 ) 1552 - 1555   2015.4Syntheses of chondroitin sulfate tetrasaccharide structures containing 4,6-disulfate patterns and analysis of their interaction with glycosaminoglycan-binding proteinReviewed

M. Wakao, R. Obata, K. Miyachi, Y. Kakitsubata, T. Kondo, C. Sakami, Y. Suda .  Synthesis of a chondroitin sulfate disaccharide library and a GAG-binding protein interaction analysis .  Bioorg. Med. Chem. Lett. 25 ( 7 ) 1407 - 1411   2015.4Synthesis of a chondroitin sulfate disaccharide library and a GAG-binding protein interaction analysisReviewed

H. Shinchi, M. Wakao, S. Nakagawa, M. Sakamoto, E. Mochizuki, T. Uematsu, S. Kuwabata, Y. Suda .  Cadmium-free sugar-chain-immobilized fluorescent nanoparticles containing low-toxicity ZnS-AgInS2 cores for probing lectine and cells .  Bioconjugate Chem.25 ( 2 ) 286 - 295   2014.2Cadmium-free sugar-chain-immobilized fluorescent nanoparticles containing low-toxicity ZnS-AgInS2 cores for probing lectine and cellsReviewed

H. Koyama, Z. Zhang,R. Ijuin, Siqin, J. Son, Y. Hatta, M. Ohta, M. Wakao, T. Hosoya, H. Doi, M. Suzuki .  Pd-0-mediated rapid coupling of methyl iodide with excess amounts of benzyl- and cinnamylboronic acid esters: efficient method for incorporation of positron-emitting C-11 radionuclide into organic frameworks by coupling between two sp(3)-hybridized carbons .  RSC Advances3 ( 24 ) 9391 - 9401   2013.6Pd-0-mediated rapid coupling of methyl iodide with excess amounts of benzyl- and cinnamylboronic acid esters: efficient method for incorporation of positron-emitting C-11 radionuclide into organic frameworks by coupling between two sp(3)-hybridized carbonsReviewed

H. Shinchi, M. Wakao, S. Nakagawa, E. Mochizuki, S. Kuwabata, Y. Suda .  Stable sugar-chain-immobilized fluorescent nanoparticles for probing lectine and cells .  Chem. Asian J.7 ( 11 ) 2678 - 2682   2012.11Stable sugar-chain-immobilized fluorescent nanoparticles for probing lectine and cellsReviewed

X. Zhang, S. Nakamura-Tsuruta, M. Haruyama, R. Yokoyama, M. Nagatomo, M. Wakao, K. Nakajima, K. Aoyama, T. Okuno, S. Morikawa, S. Hiroi, T. Kase, H. Nose, J. Nishi, M. Okamoto, M. Baba, Y. Suda .  Super high sensitive detection of viruses using sugar-chain immobilized gold nano-particles (SGNPs) .  Polymer Preprints53 ( 1 ) 671 - 672   2012.3Super high sensitive detection of viruses using sugar-chain immobilized gold nano-particles (SGNPs)Reviewed

K. Fujita, S. Sakamoto, Y. Ono, M. Wakao, Y. Suda, K. Kitahara, T. Suganuma .  Molecular cloning and characterization of a beta-L-Arabinobiosidase in Bifidobacterium longum that belongs to a novel glycoside hydrolase family .  J. Biol. Chem.286 ( 7 ) 5143 - 5150   2011.2Molecular cloning and characterization of a beta-L-Arabinobiosidase in Bifidobacterium longum that belongs to a novel glycoside hydrolase familyReviewed

藤田清貴、坂元志帆、小野祐樹、若尾雅広、隅田泰生、北原兼文、菅沼俊彦 .  ビフィズス菌由来β-L-アラビノビオシダーゼの機能解析 .  応用糖質科学1 ( 2 ) 153 - 158   2011.2ビフィズス菌由来β-L-アラビノビオシダーゼの機能解析Reviewed

E. Wijelath, M. Namekata, J. Murray, M. Furuyashiki, S.-Y. Zhang, D. Coan, M. Wakao, R. B. Harris, Y. Suda, L.-C. Wang, M. Sobel .  Multiple Mechanisms for Exogenous Heparin Modulation of Vascular Endothelial Growth Factor Activity .  J. CELLULAR BIOCHEM. 111 ( 2 ) 461 - 468   2010.10Multiple Mechanisms for Exogenous Heparin Modulation of Vascular Endothelial Growth Factor ActivityReviewed

A. Saito, M. Wakao, H. Deguchi, A. Mawatari, M. Sobel, Y. Suda .  Toward the assembly of heparin and heparan sulfate oligosaccharide libraries: efficient synthesis of uronic acid and disaccharide building blocks .  Tetrahedron66 ( 22 ) 3951 - 3962   2010.5Toward the assembly of heparin and heparan sulfate oligosaccharide libraries: efficient synthesis of uronic acid and disaccharide building blocksReviewed

N. Sasaki, T. Hirano, T. Ichimiya, M. Wakao, K. Hirano, A. Kinoshita-Toyoda, H. Toyoda, Y. Suda, S. Nishihara .  The 3'-phosphoadenosine 5'-phosphosulfate transporters, PAPST1 and 2, contribute to the maintenance and differentiation of mouse embryonic stem cells .  PLoS ONE4   e8262   2009.12The 3'-phosphoadenosine 5'-phosphosulfate transporters, PAPST1 and 2, contribute to the maintenance and differentiation of mouse embryonic stem cellsReviewed

M. Sato, Y. Ito, N. Arima, M. Baba, M. Sobel, M. Wakao, Y. Suda .  High-Sensitivity Analysis of Naturally Occurring Sugar Chains, Using a Novel Fluorescent Linker Molecule .  J. BIOCHEM.146 ( 1 ) 33 - 41   2009.7High-Sensitivity Analysis of Naturally Occurring Sugar Chains, Using a Novel Fluorescent Linker Molecule Reviewed

A. Imamura, T. Yoshikawa, T. Komori, M. Ando, H. Ando, M. Wakao, Y. Suda, H. Ishida, M. Kiso .  Design and synthesis of versatile ganglioside probes for carbohydrate microarrays .  Glycoconjugate J.25 ( 3 ) 269 - 278   2008.4Design and synthesis of versatile ganglioside probes for carbohydrate microarraysReviewed

M. Wakao, A. Saito, K. Ohishi, Y. Kishimoto, T. Nishimura, M. Sobel, Y. Suda .  Sugar Chips immobilized with synthetic sulfated disaccharides of heparin/heparan sulfate partial structure .  Bioorg. Med. Chem. Lett. 18 ( 7 ) 2499 - 2504   2008.4Sugar Chips immobilized with synthetic sulfated disaccharides of heparin/heparan sulfate partial structure Reviewed

Y. Suda, Y. Kishimoto, T. Nishimura, S. Yamashita, M. Hamamatsu, A. Saito, M. Sato, M. Wakao .  Sugar-Immobilized Gold Nano-Particles (SGNP): Novel Bioprobe for the On-Site analysis of the Oligosaccharide-Protein Interactions .  Polymer Preprints47 ( 2 ) 156 - 157   2006.9Sugar-Immobilized Gold Nano-Particles (SGNP): Novel Bioprobe for the On-Site analysis of the Oligosaccharide-Protein InteractionsReviewed

Yasuo Suda, Akio Arano, Yasuhiro Fukui, Shuhei Koshida, Masahiro Wakao, Tomoaki Nishimura,Shoichi Kusumoto, and Michael Sobel .  Immobilization and clustering of structurally defined oligosaccharides for sugar chips: An improved method for surface plasmon resonance analysis of protein-carbohydrate interactions .  Bioconj. Chem.17 ( 5 ) 1125 - 1135   2006.9Immobilization and clustering of structurally defined oligosaccharides for sugar chips: An improved method for surface plasmon resonance analysis of protein-carbohydrate interactionsReviewed

T. Hosoya, K. Sumi, H. Doi, M. Wakao, M. Suzuki .  Rapid methylation on carbon frameworks useful for the synthesis of 11CH3-incorporated PET tracers: Pd(0)-mediated rapid coupling of methyl iodide with an alkenyltributylstannane leading to a 1-methylalkene .  Org. Biomol. Chem.4 ( 3 ) 410 - 415   2006.1Rapid methylation on carbon frameworks useful for the synthesis of 11CH3-incorporated PET tracers: Pd(0)-mediated rapid coupling of methyl iodide with an alkenyltributylstannane leading to a 1-methylalkeneReviewed

20 Conventional and Easy Analysis of Virus-Binding GAG Structure Using Array-Type Sugar Chip In: Glycoscience: Biology and Medicine, Editors: Taniguchi, N., Endo, T., Hart, G.W., Seeberger, P.H., Wong, C.-H. (Eds.)

Yasuo Suda, Xu Zhang, Sachiko Nakamura-Tsuruta, Michael Sobel, Toshiomi Okuno, Masahiro Wakao（ Role： Contributor ,  Conventional and Easy Analysis of Virus-Binding GAG Structure Using Array-Type Sugar Chip）

Springer Japan  2015 

村田光紀、加藤健太郎、若尾雅広、隅田泰生、新地浩之   レクチンプルダウン法による糖鎖—レクチン間相互作用の解析  

第43回日本糖質学会年会  日本糖質学会

村田光紀、早川尚宏、若尾雅広、隅田泰生、新地浩之   金ナノ粒子をキャリアに用いたセルフ・アジュバント機能を有する組換えタンパクワクチンの開発  

日本化学会第104春季年会  日本化学会

赤池駿弥、若尾雅広、隅田泰生、新地浩之   生理的条件下で安定に分散する金ナノ粒子の合成  

日本化学会第104春季年会  日本化学会

村田光紀、下田真唯子、新村真由美、若尾雅広、隅田泰生、諸石寿朗、新地浩之   合成TLR9リガンドのα-マンノース固定化金ナノ粒子への複合化によるアジュバント効果の増強  

第96回日本生化学会大会  日本生化学会

寿福稜、新地浩之、隅田泰生、若尾雅広   TLR7リガンド-糖鎖複合体をアジュバントに用いた経鼻投与型不活化ワクチンの開発  

第96回日本生化学会大会  日本生化学会

髙山優香、東雅也、和田詩帆、新地浩之、隅田泰生、若尾雅広   TLR7リガンド-糖鎖複合体の合成と免疫増強活性評価  

第42回日本糖質学会年会  2023.9  日本糖質学会

Ryo Jufuku, Hiroyuki Shinchi, Yasuo Suda, Masahiro Wakao   Development of an ELISA-based analytical method for the interaction of sugar binding proteins using sugar-immobilized gold nanoparticles   International conference

Glyco26  IGO

Seigo Tateo, Hiroyuki Shinchi, Makoto Yoshimitsu, Yuichiro Uchida, Masahiro Wakao, Yasuo Suda   Development of sugar chain binding chimeric antigen receptor expressed natural killer cells for immunotherapy against adult T cell leukemia (ATL)   International conference

Glyco26  IGO

Koki Murata, Ryo Jufuku, Mayuko Shimoda, Mayumi Niimura, Masahiro Wakao, Yasuo Suda, Toshiro Moroishi, Hiroyuki Shinchi   Enhancement of immunostimulatory activity of CpG oligo deoxynucleotide by conjugation to α-mannose immobilized gold nanoparticles   International conference

Glyco26  IGO

和田詩帆、村田光紀、新村真由美、下田真唯子、若尾雅広、隅田泰生、諸石寿朗、新地浩之   糖鎖ナノアジュバントを用いたセルフ・アジュバント型ペプチドワクチンの免疫誘導活性  

令和５年度日本生化学会九州支部例会  2023.6  日本生化学会

赤池駿弥、若尾雅広、隅田泰生、諸石寿朗、新地浩之   TLR7リガンド・糖鎖共固定化金ナノ粒子の粒径および糖鎖構造が免疫刺激活性に与える影響  

令和５年度日本生化学会九州支部例会  2023.6  日本生化学会

村田光紀、下田真唯子、新村真由美、若尾雅広、隅田泰生、諸石寿朗、新地浩之   金ナノ粒子に固定化したTLR9リガンドのヌクレアーゼ耐性と免疫増強活性  

令和５年度日本生化学会九州支部例会  2023.6  日本生化学会

Koki Murata, Mayuko Shimoda, Mayumi Niimura, Masahiro Wakao, Yasuo Suda, Toshiro Moroishi, Hiroyuki Shinchi   Development of Glyco-Nanoadjunvats that consisted of gold nanoparticles co-immobilized with synthetic TLR9 ligand and sugar molecule  

2023.3 

Ryoma Hayase, Kensuke Sameshima, Masahiro Wakao, Yasuo Suda   Synthetic study on heparan sulfate partial disaccharide structures containing GlcNAc3S-IdoA sequence  

2023.3 

Shiho Wada, Koki Murata, Haruka Ohara, Mayumi Niimura, Mayuko Shimoda, Masahiro Wakao, Yasuo Suda, Toshiro Moroishi, Hiroyuki Shinchi   Development of novel self-adjuvanting peptide vaccine using Glyco-Nanoadjuvant  

2023.3 

新村真由美、下田真唯子、村田光紀、大原遥、竹島裕貴、Chanida Thinyakul, 原田成美、Liu S、若尾雅広、新地浩之、諸石寿朗   金ナノ粒子キャリアを用いたアジュバント・糖鎖・抗原一体型ワクチンの抗腫瘍効果  

第45回日本分子生物学会年会  2022.11  日本分子生物学会

Ryoma Hayase, Kensuke Sameshima, Masahiro Wakao, Yasuo Suda   Synthetic study on heparan sulfate partial disaccharide structures containing GlcNAc3S-IdoA sequence  

2022.3 

池田康朗、藤田直樹、若尾雅広、隅田泰生   IdoA3Sを含むデルマタン硫酸二糖構造に関する合成研究  

日本化学会第101春季年会  2021.3  日本化学会

藤田直樹、神田凌平、池田康朗、若尾雅広、隅田泰生   コンドロイチン硫酸二糖ビルディングブロックの高効率合成に関する研究  

日本化学会第101春季年会  2021.3  日本化学会

飯干寛太、若尾雅広、隅田泰生   ムチン型糖鎖コア6構造に関する合成研究   Invited

第39回日本糖質学会年会  日本糖質学会

幸勝治、新地浩之、若尾雅広、隅田泰生   TLR7リガンド・糖鎖共固定化ナノ粒子の免疫増強活性のメカニズム解析   Invited

第39回日本糖質学会年会  日本糖質学会

長友琴愛、中本憲孝、若尾雅広、隅田泰生   グルクロン酸含有ヘパラン硫酸部分四糖構造に関する合成研究   Invited

第39回日本糖質学会年会  日本糖質学会

戸田薫、飯干寛太、若尾雅広、隅田泰生   ムチン型糖鎖コア7構造に関する合成研究   Invited

第39回日本糖質学会年会  日本糖質学会

幸勝治、新地浩之、山内隆好、諸石寿朗、若尾雅広、隅田 泰生   糖鎖固定化金ナノ粒子をキャリア分子としたTLR7リガンドの免疫増強活性評価   Invited

第93回日本生化学会大会  2020.9  日本生化学会

真辺賢了、新地浩之、若尾雅広、隅田泰生   低環境負荷性糖鎖固定化蛍光性カーボンナノ粒子の開発  

令和２年度日本生化学会九州支部例会  日本生化学会

立尾清悟、伊藤美咲、新地浩之、若尾雅広、隅田泰生   成人T細胞白血病に対する光線力学療法の開発  

令和２年度日本生化学会九州支部例会  日本生化学会

中原健成、新地浩之、若尾雅広、隅田泰生   ワクチンアジュバントとしてのTLR7リガンド・糖鎖固定化金ナノ粒子  

令和２年度日本生化学会九州支部例会  日本生化学会

鮫島健介、長友琴愛、市吉賢太、若尾雅広、隅田泰生   GlcN-IdoA配列含有ヘパラン硫酸二糖部分構造に関する合成研究  

日本化学会第100春季年会  日本化学会

真辺賢了、新地浩之、若尾雅広、隅田　泰生   低環境負荷性糖鎖固定化蛍光性カーボンナノ粒子（SFCNP）の開発  

日本化学会第100春季年会  日本化学会

若尾雅広、新地浩之、隅田泰生、馬場暁士、Michael Chan、林公子、Howard B. Cottam、Dennis A. Carson   糖鎖?TLR7リガンド複合体の合成と免疫増強活性  

第25回 日本エンドトキシン・自然免疫研究会   日本エンドトキシン・自然免疫研究会

Yumi Matsubayashi, Kaito Hashiguchi, Hiroyuki Shinchi, Masahiro Wakao, Yasuo Suda   Development of single chain variable fragment antibody which recognizes sialyl Tn antigen  

NDSU-KU Joint Symposium on Biotechnology, Nanomaterials and Polymers  NDSU-KU Joint Symposium on Biotechnology, Nanomaterials and Polymers

Hirona Shimoda, Seigo Tateo, Kaname Muchima, Hiroyuki Shinchi, Masahiro Wakao, Shogo Nakano, Sohei Ito, Hiroaki Tokiwa, Yasuo Suda   Modification of sugar-chains-binding single-chain variable fragment antibody based on bioinformatics  

NDSU-KU Joint Symposium on Biotechnology, Nanomaterials and Polymers  NDSU-KU Joint Symposium on Biotechnology, Nanomaterials and Polymers

Kanta Iiboshi, Kaoru Toda, Masahiro Wakao, Yasuo Suda   Synthetic study on core structures of mucin-type O-glycan  

NDSU-KU Joint Symposium on Biotechnology, Nanomaterials and Polymers  NDSU-KU Joint Symposium on Biotechnology, Nanomaterials and Polymers

Kotomi Nagatomo, Kensuke Sameshima, Kenta Ichiyoshi, Masahiro Wakao, Yasuo Suda   Synthetic study on heparan sulfate tetrasaccharide structure that contains glucuronic acid  

NDSU-KU Joint Symposium on Biotechnology, Nanomaterials and Polymers  NDSU-KU Joint Symposium on Biotechnology, Nanomaterials and Polymers

Masaharu Yuki, Hiroyuki Shinchi, Masahiro Wakao, Yasuo Suda   Development of toll-like receptor 7 ligand and sugar chain immobilized fluorescent nanoparticles  

NDSU-KU Joint Symposium on Biotechnology, Nanomaterials and Polymers  NDSU-KU Joint Symposium on Biotechnology, Nanomaterials and Polymers

Masayuki Yada, Kaito Hashiguchi, Masahiro Wakao, Hiroyuki Shinchi, Yasuo Suda   Synthetic study on novel sialyl Tn antigen containing N-glycolylneuraminic acid  

NDSU-KU Joint Symposium on Biotechnology, Nanomaterials and Polymers  NDSU-KU Joint Symposium on Biotechnology, Nanomaterials and Polymers

Hayate Sawayama, Yuki Enjoji, Hiroyuki Shinchi, Masahiro Wakao, Yuji Ito, Yasuo Suda   Development of sugar chain binding single chain variable fragment antibody to HPV-infected cells toward molecular targeted therapy  

NDSU-KU Joint Symposium on Biotechnology, Nanomaterials and Polymers  NDSU-KU Joint Symposium on Biotechnology, Nanomaterials and Polymers

Seigo Tateo, Shogo Tokizaki, Misaki Ito, Hiroyuki Shinchi, Masahiro Wakao, Yasuo Suda   Toward diagnostic and therapeutic agent for adult T cell leukemia using fluorescent nanoparticles immobilized with sigle chain variable fragment antibody  

NDSU-KU Joint Symposium on Biotechnology, Nanomaterials and Polymers  NDSU-KU Joint Symposium on Biotechnology, Nanomaterials and Polymers

Shiho Hayashi, Takafumi Hayashi, Yuki Kinoue, Masahiro Wakao, Yasuo Suda   Synthetic study on keratin sulfate partial structure library  

NDSU-KU Joint Symposium on Biotechnology, Nanomaterials and Polymers  NDSU-KU Joint Symposium on Biotechnology, Nanomaterials and Polymers

Takuma Nakatake, Hiroyuki Shinchi, Masahiro Wakao, Yasuo Suda   Study on sulphated sugar chain-binding single chain variable fragment antibodies  

NDSU-KU Joint Symposium on Biotechnology, Nanomaterials and Polymers  NDSU-KU Joint Symposium on Biotechnology, Nanomaterials and Polymers

Yuki Enjoji, Hayate Sawayama, Hiroyuki Shinchi, Masahiro Wakao, Yuji Ito, Yasuo Suda   Development of single chain variable fragment antibodies to cell surface N-glycan on cervical cancer cell line  

NDSU-KU Joint Symposium on Biotechnology, Nanomaterials and Polymers  NDSU-KU Joint Symposium on Biotechnology, Nanomaterials and Polymers

円城寺佑貴、中竹拓馬、松林由眞、澤山颯、新地浩之、若尾雅広、伊東祐二、隅田泰生   子宮頸がん細胞表層のN-型糖鎖に結合する一本鎖抗体の開発  

第92回日本生化学会大会  日本生化学会

Takenari Nakahara, Toru Yamaguchi, Shuto Usuyama Hiroyuki Shinchi, Masahiro Wakao, Yasuo Suda   Sugar Chain and TLR Ligands Immobilized Gold Nanoparticles for Vaccine Agent  

Taiwan-Japan Bilateral Workshop 2019 (TJBW-2019)  Taiwan-Japan Bilateral Workshop 2019 (TJBW-2019)

Takafumi Hayashi, Shiho Hayashi, Yuki Kinoue, Tatsuyuki Yoshida, Masahiro Wakao, Yasuo Suda   Synthetic study on keratan sulfate partial disaccharide unit library  

Taiwan-Japan Bilateral Workshop 2019 (TJBW-2019)  Taiwan-Japan Bilateral Workshop 2019 (TJBW-2019)

Ryuho Tanaka, Shinya Oyama, Toru Yamaguchi, Hiroyuki Shinchi, Howard B. Cottam, Michael Chan, Tomoko Hayashi, Dennis A. Carson, Masahiro Wakao, Yasuo Suda   Synthetic Study on Toll-Like Receptor-4 Ligand Composed of 8-Aryl-3,5-dihydro-4H-pyrimido[5,4-b]indolone Framework  

Taiwan-Japan Bilateral Workshop 2019 (TJBW-2019)  Taiwan-Japan Bilateral Workshop 2019 (TJBW-2019)

Yoshiaki Manabe, Yurina Ata, Hiroyuki Shinchi, Masahiro Wakao, Yasuo Suda   Preparation of Sugar Chain immobilized Fluorescent Carbon Nanoparticles toward the Safer Metal-Free Analytical Tool  

Taiwan-Japan Bilateral Workshop 2019 (TJBW-2019)  Taiwan-Japan Bilateral Workshop 2019 (TJBW-2019)

Kensyke Sameshima, Kotomi Nagatomo, Kenta Ichiyoshi, Masahiro Wakao, Yasuo Suda   Synthetic Study on Heparan Sulfate Disaccharide Partial Structures Containing Iduronic Acids  

Taiwan-Japan Bilateral Workshop 2019 (TJBW-2019)  Taiwan-Japan Bilateral Workshop 2019 (TJBW-2019)

Naoki Fujita, Ryohei Kanda, Yasuaki Ikeda, Masahiro Wakao, Yasuo Suda   Synthetic Study on Chondroitin Sulfate Partial Tetrasaccharide structure with CS-T+T sequence  

Taiwan-Japan Bilateral Workshop 2019 (TJBW-2019)  Taiwan-Japan Bilateral Workshop 2019 (TJBW-2019)

Seigo Tateo, Shogo Tokizaki, Hiroyuki Shinchi, Masahiro Wakao, Yasuo Suda   Fluorescent Nanoparticle Immobilized with Single Chain Variable Fragment Antibody for the Diagnostic/Therapeutic Tools toward Adult T Cell Leukemia  

Taiwan-Japan Bilateral Workshop 2019 (TJBW-2019)  Taiwan-Japan Bilateral Workshop 2019 (TJBW-2019)

澤山颯、円城寺佑貴、新地浩之、若尾雅広、伊東祐二、隅田泰生   子宮頚がん細胞表層糖鎖特異的に結合する一本鎖抗体の探索  

第43回蛋白質と酵素の構造と機能に関する九州シンポジウム  日本生化学会

Hiroyuki Shinchi, Toru Yamaguchi, Toshiro Moroishi, Tomoko Hayashi, Howard B. Cottam, Dennis A. Carson, Masahiro Wakao, Yasuo Suda   Development of toll-like receptor 7 ligand and α-mannose immobilized gold nanoparticles toward adjuvant immunotherapy   International conference

ACS Fall 2019 National Meeting & Expo  American Chemical Society (ACS)

林志帆、林昂史、吉田龍幸、若尾雅広、隅田泰生   ケラタン硫酸二糖ユニットに関する合成研究  

第38回日本糖質学会年会  日本糖質学会

鮫島健介、長友琴愛、市吉賢太、若尾雅広、隅田泰生   イズロン酸含有ヘパラン硫酸部分二糖構造に関する合成研究  

第38回日本糖質学会年会  日本糖質学会

新地浩之、山口徹、幸勝治、臼山秀人、中原健成、立尾清悟、諸石寿朗、若尾雅広、林 公子、Howard B. Cottam、Dennis A. Carson、隅田泰生   TLR7リガンドと糖鎖を固定化した金ナノ粒子の免疫増強活性とワクチンへの応用  

第29回抗ウイルス療法学会  抗ウイルス療法学会

幸勝治、新地浩之、若尾雅広、隅田泰生   Toll様受容体7リガンド・糖鎖共固定化蛍光性ナノ粒子の開発  

平成31年度日本生化学会九州支部例会  日本生化学会

立尾清悟、時崎照吾、新地浩之、若尾雅広、隅田秦生   一本鎖抗体固定化蛍光ナノ粒子を用いた成人T細胞白血病に対する光線力学療法の開発  

平成31年度日本生化学会九州支部例会  日本生化学会

橋口海斗、矢田将之、飯干寛太、若尾雅広、隅田泰生   N-グリコリルノイラミン酸含有シアリルTn抗原糖鎖の合成と相互作用解析  

日本化学会第99春季年会  日本化学会

山口徹、新地浩之、若尾雅広、林公子、Cottam Howard, Carson Dennis, 隅田泰生   新規アジュバントとしてのTLR7リガンド・糖鎖固定化金ナノ粒子の開発  

第24回 日本エンドトキシン・自然免疫研究会   日本エンドトキシン・自然免疫研究会

Masayuki Yada, Kaito Hashiguchi, Kanta Iiboshi, Masahiro Wakao, Hiroyuki Shinchi, Yasuo Suda   Synthetic study on Neu5Gc2-6GalNAc1-Ser, N-glycolylneuraminic acid containing Sialyl Tn antigen  

KU-NDSU Joint Symposium on Biotechnology, Nanomaterials and Polymers  KU-NDSU Joint Symposium on Biotechnology, Nanomaterials and Polymers

Masahiro Wakao, Akihito Baba, Hiroyuki Shinchi, Howard B. Cottam, Michael Chan, Tomoko Hayashi, Dennis A. Carson, Yasuo Suda   Synthesis and Biological Evaluation of Sugar chain-conjugates with Toll-like Receptor 7 Ligand  

KU-NDSU Joint Symposium on Biotechnology, Nanomaterials and Polymers  KU-NDSU Joint Symposium on Biotechnology, Nanomaterials and Polymers

Hiroyuki Shinchi, Masahiro Wakao, Yasuo Suda   Preparation and application of sugar chain-immobilized fluorescent nanoparticles  

KU-NDSU Joint Symposium on Biotechnology, Nanomaterials and Polymers  KU-NDSU Joint Symposium on Biotechnology, Nanomaterials and Polymers

Hayate Sawayama, Yuki Enjoji, Hiroyuki Shinchi, Masahiro Wakao, Yuji Ito, Yasuo Suda   Development of single chain variable fragment antibody (scFv) to sugar chains on HPV-infected cells toward molecular targeted therapy of cancer  

KU-NDSU Joint Symposium on Biotechnology, Nanomaterials and Polymers  KU-NDSU Joint Symposium on Biotechnology, Nanomaterials and Polymers

Shintaro Ishimaru, Hirona Shimoda, Hiroyuki Shinchi, Masahiro Wakao, Yuji Ito, Yasuo Suda   Development of single chain variable fragment antibodies which bind to sulphated sugar chains  

KU-NDSU Joint Symposium on Biotechnology, Nanomaterials and Polymers  KU-NDSU Joint Symposium on Biotechnology, Nanomaterials and Polymers

Shinya Oyama, Ryuho Tanaka, Toru Yamaguchi, Hiroyuki Shinchi, Masahiro Wakao, Howard B. Cottam, Michael Chan, Tomoko Hayashi, Dennis A. Carson, Yasuo Suda   Synthetic study on Toll-like receptor 4 ligands  

KU-NDSU Joint Symposium on Biotechnology, Nanomaterials and Polymers  KU-NDSU Joint Symposium on Biotechnology, Nanomaterials and Polymers

Shogo Tokizaki, Seigo Tateo, Hiroyuki Shinchi, Masahiro Wakao, Yasuo Suda   Study on photodynamic therapy against adult T cell leukemia using fluorescenet nanoparticles immobilized with single chain variable fragemet antibody  

KU-NDSU Joint Symposium on Biotechnology, Nanomaterials and Polymers  KU-NDSU Joint Symposium on Biotechnology, Nanomaterials and Polymers

Noritaka Nakamoto, Rikiya Aramaki, Kensuke Sameshima, Kotomi Nagatomo, Masahiro Wakao, Yasuo Suda   Synthetic study on heparan sulfate partial tetrasaccharide structures containing glucuronic acid moiety  

KU-NDSU Joint Symposium on Biotechnology, Nanomaterials and Polymers  KU-NDSU Joint Symposium on Biotechnology, Nanomaterials and Polymers

Takafumi Hayashi, Yuki Kinoue, Shiho Hayashi, Masahiro Wakao, Yasuo Suda   Synthetic study on keratan sulfate partial structure library  

KU-NDSU Joint Symposium on Biotechnology, Nanomaterials and Polymers  KU-NDSU Joint Symposium on Biotechnology, Nanomaterials and Polymers

Toru Yamaguchi, Hiroyuki Shinchi, Masaharu, Yuki, Tomoko, Hayashi, Howard B. Cottom, Dennis A. Carson, Masahiro Wakao, Yasuo Suda   Development of gold nanoparticles immobilized with toll-like receptor-7 ligand molecule and sugar chains toward versatile vaccine platform  

KU-NDSU Joint Symposium on Biotechnology, Nanomaterials and Polymers  KU-NDSU Joint Symposium on Biotechnology, Nanomaterials and Polymers

Yuki Enjoji, Hayate Sawayama, Takuma Nakatake, Yumi Matubayashi, Hiroyuki Shinchi, Masahiro Wakao, Yuji Ito, Yasuo Suda   Development of single chain variable fragment antibodies (scFvs) which recognize cell surface sugar chain on HPV-infected cells for targeted therapy  

KU-NDSU Joint Symposium on Biotechnology, Nanomaterials and Polymers  KU-NDSU Joint Symposium on Biotechnology, Nanomaterials and Polymers

Ryohei Kanda, Naoki Fujita, Masahiro Wakao, Yasuo Suda   Synthetic study on uronic acid building blocks for construction of chondroitin sulfate/dermatan sulfate partial structure library  

KU-NDSU Joint Symposium on Biotechnology, Nanomaterials and Polymers  KU-NDSU Joint Symposium on Biotechnology, Nanomaterials and Polymers

Kensuke Sameshima, Noritaka Nakamoto, Kotomi Nagatomo, Masahiro Wakao, Yasuo Suda   Synthetic study on heparan sulfate partial structures that contain iduronic acids  

KU-NDSU Joint Symposium on Biotechnology, Nanomaterials and Polymers  KU-NDSU Joint Symposium on Biotechnology, Nanomaterials and Polymers

Seigo Tateo, Kaname Muchima, Hiroyuki Shinchi, Masahiro Wakao, Shogo Nakano, Sohei Ito, Hiroaki Tokiwa, Yasuo Suda   Improvement of the sulfated sugar chains-binding single chain variable fragment antibody (scFv) through gene engineering and bioinformatics  

KU-NDSU Joint Symposium on Biotechnology, Nanomaterials and Polymers  KU-NDSU Joint Symposium on Biotechnology, Nanomaterials and Polymers

Ryuho Tanaka, Shinya Oyama, Toru Yamaguchi, Hiroyuki Shinchi, Howard B. Cottam, Michael Chan, Tomoko Hayashi, Dennis A. Carson, Masahiro Wakao, Yasuo Suda   Synthetic study on Toll-like receptor 4 ligand composed of 8-aryl-3,5-dihydro-4H-pyrimido[5,4-b]indolone framework  

KU-NDSU Joint Symposium on Biotechnology, Nanomaterials and Polymers  KU-NDSU Joint Symposium on Biotechnology, Nanomaterials and Polymers

立尾清悟、鞭馬奏萌、新地浩之、若尾雅広、中野祥吾、伊藤創平、常盤明広、隅田泰生   遺伝子組み換えとバイオインフォマティクスによる糖鎖結合性一本鎖抗体の改変  

第91回日本生化学会大会  日本生化学会

藤田清貴、石渡明弘、伊藤幸成、若尾雅広、隅田泰生、北原兼文   Aureobacterium sp. M2由来の組み替えendo-D-arabinaseの機能解析  

第91回日本生化学会大会  日本生化学会

林昂史、木上雄輝、若尾雅広、隅田泰生   フコース含有ケラタン硫酸部分構造に関する合成研究  

第37回日本糖質学会年会  日本糖質学会

Toru Yamaguchi, Hiroyuki Shinchi, Tomoko, Hayashi, Howard B. Cottom, Dennis A. Carson, Masahiro Wakao, Yasuo Suda   Development of toll-like receptor ligand immobilized gold nanoparticles toward versatile vaccine platform  

Taiwan-Japan Bilateral Workshop (2018TJBW)  Taiwan-Japan Bilateral Workshop (2018TJBW)

Akihito Baba, Hiroyuki Shinchi, Masahiro Wakao, Howard B. Cottam, Michael Chan, Tomoko Hayashi, Dennis A. Carson, Yasuo Suda   Synthesis and Biological Evaluation of Sugar chain-conjugates with Toll-like Receptor 7 Ligand  

Taiwan-Japan Bilateral Workshop (2018TJBW)  Taiwan-Japan Bilateral Workshop (2018TJBW)

Hiroyuki Shinchi, Toru Yamaguchi, Brian Crain, Shin Yao, Michael Chan, Shannon S. Zhang, Alast Ahmadiiveli, Yasuo Suda, Tomoko Hayashi, Howard B. Cottam, Dennis A. Carson   Development of effective vaccine adjuvants using small toll-like receptor 7 ligand molecules  

Taiwan-Japan Bilateral Workshop (2018TJBW)  Taiwan-Japan Bilateral Workshop (2018TJBW)

Takafumi Hayashi, Yuki Kinoue, Masahiro Wakao, Yasuo Suda   Synthetic study on keratan sulfate partial structure library  

Taiwan-Japan Bilateral Workshop (2018TJBW)  Taiwan-Japan Bilateral Workshop (2018TJBW)

Shinya Oyama, Toru Yamaguchi, Hiroyuki Shinchi, Masahiro Wakao, Howard B. Cottam, Michael Chan, Tomoko Hayashi, Dennis A. Carson, Yasuo Suda   Synthetic study on Toll-like receptor 4 ligands  

Taiwan-Japan Bilateral Workshop (2018TJBW)  Taiwan-Japan Bilateral Workshop (2018TJBW)

Seigo Tateo, Kaname Muchima, Hiroyuki Shinchi, Masahiro Wakao, Shogo Nakano, Sohei Ito, Hiroaki Tokiwa, Yasuo Suda   Development of sugar chain binding single chain variable fragment antibody toward targeted therapy for adult T-cell leukaemia  

Taiwan-Japan Bilateral Workshop (2018TJBW)  Taiwan-Japan Bilateral Workshop (2018TJBW)

時崎照吾、立尾清吾、新地浩之、若尾雅広、隅田泰生   蛍光性ナノ粒子を利用した光線力学療法による成人T細胞白血病の新規治療法の開発研究  

平成30年度日本生化学会九州支部例会  日本生化学会

石丸慎太郎、新地浩之、若尾雅広、伊東祐二、隅田泰生   硫酸化糖鎖結合性一本鎖抗体の探索  

平成30年度日本生化学会九州支部例会  日本生化学会

円城寺佑貴、澤山颯、新地浩之、若尾雅広、伊東祐二、隅田泰生   子宮頸がん細胞表層糖鎖に結合する一本鎖抗体の探索  

平成30年度日本生化学会九州支部例会  日本生化学会

西村知晃、岸本裕子、山下早希子、中川裕美、佐藤昌紀、斎藤彰宏、若尾雅広、J. Murray-Wijelath、E. Wijelath、K. Strand、M. Sobel、隅田泰生   表面プラズモン共鳴を用いた糖鎖ー蛋白質相互作用の解析システム  

第25 回日本糖質学会年会  第25 回日本糖質学会年会

幸 勝治, 新地 浩之, 山内 隆好, 諸石 寿朗, 若尾 雅広, 隅田 泰生   糖鎖固定化金ナノ粒子をキャリア分子としたTLR7リガンドの免疫増強活性評価  

日本生化学会大会プログラム・講演要旨集  2020.9  (公社)日本生化学会

藤田 清貴, 石渡 明弘, 伊藤 幸成, 若尾 雅広, 隅田 泰生, 北原 兼文   Aureobacterium sp.M2由来の組み換えendo-D-arabinaseの機能解析  

日本生化学会大会プログラム・講演要旨集  2018.9  (公社)日本生化学会

円城寺 佑貴, 中竹 拓馬, 松林 由眞, 澤山 颯, 新地 浩之, 若尾 雅広, 伊東 祐二, 隅田 泰生   子宮頸がん細胞表層のN-型糖鎖に結合する一本鎖抗体の開発  

日本生化学会大会プログラム・講演要旨集  2019.9  (公社)日本生化学会

山口 徹, 新地 浩之, 若尾 雅広, 林 公子, Howard Cottom, Dennis Carson, 隅田 泰生   TLR7リガンド固定化金ナノ粒子の調製と免疫増強活性評価  

生命科学系学会合同年次大会  2017.12  生命科学系学会合同年次大会運営事務局

METHOD FOR CONCENTRATING VIRUSES,METHOD FOR CONCENTRATING CELLS OR BACTERIA, AND MAGNETIC COMPOSITE

ウイルスの濃縮方法および磁性体組成物

隅田泰生，若尾雅広，児玉 崇

多岐用途型蛍光性リンカー化合物、及びその製造方法ならびにそれを用いて製造するリガンド複合体

隅田泰生，若尾雅広，佐藤昌紀，馬場昌範，有馬直道，伊東祐二

生体関連物質と糖鎖との相互作用の測定方法、生体関連物質の糖鎖選択性の評価方法、生体関連物質のスクリーニング方法、および生体関連物質のパターニング方法、並びにこれらの方法を実施するためのキット

隅田泰生，西村知晃，岸本裕子，山下早希子，鶴田祥子，若尾雅広，奥野壽臣

支持体に対する金属微粒子膜の形成方法及び局在プラズモン共鳴センサ

若尾雅広，隅田泰生，小川智央

リンカー化合物及びリガンド複合体、並びにそれらの製造方法

隅田泰生，荒野明男，楠本正一，ソベール・マイケル，若尾雅広