Updated on 2023/12/06

写真a

 
INDO Hiroko
 
Organization
Research Field in Dentistry, Medical and Dental Sciences Area Graduate School of Medical and Dental Sciences Advanced Therapeutics Course Oncology Associate Professor
Title
Associate Professor

Degree

  • 博士(歯学) ( 2003.1   鹿児島大学 )

Research Areas

  • Others / Others  / 歯科放射線学

  • Others / Others  / 画像診断

  • Others / Others  / ミトコンドリア学

  • Life Science / Radiological sciences  / 放射線治療

Research History

  • Kagoshima University   Associate Professor

    2015.4

  • Kagoshima University   Assistant Professor

    2007.4 - 2015.3

  • Kagoshima University   Research Assistant

    2003.4 - 2007.3

  • Kagoshima University   Research Assistant

    1997.10 - 2003.3

Professional Memberships

  • 日本放射線腫瘍学会

    2016.9

  • 日本ミトコンドリア学会

    2005

  • 日本酸化ストレス学会

    2004.6

  • 日本放射線影響学会

    2002.1

  • 日本歯科放射線学

    1997

Committee Memberships

  • 日本歯科放射線学会   評議員  

    2022   

  • 日本酸化ストレス学会   理事   

    2020   

  • 日本酸化ストレス学会   代議員  

    2015   

Qualification acquired

  • Specialist

 

Papers

  • Cornette R., Indo H.P., Iwata K.i., Hagiwara-Komoda Y., Nakahara Y., Gusev O., Kikawada T., Okuda T., Majima H.J. .  Oxidative stress is an essential factor for the induction of anhydrobiosis in the desiccation-tolerant midge, Polypedilum vanderplanki (Diptera, Chironomidae) .  Mitochondrion73   84 - 94   2023.11Reviewed

     More details

    Language:Japanese   Publisher:Mitochondrion  

    The sleeping chironomid (Polypedilum vanderplanki) is the only insect capable of surviving complete desiccation in an ametabolic state called anhydrobiosis. Here, we focused on the role of oxidative stress and we observed the production of reactive oxygen species (ROS) in desiccating larvae and in those exposed to salinity stress. Oxidative stress occurs to some extent in desiccating larvae, inducing carbonylation of proteins. Oxidative stress overcomes the antioxidant defenses of the larvae during the first hour following rehydration of anhydrobiotic larvae. It facilitates the oxidation of DNA and cell membrane lipids; however, these damages are quickly repaired after a few hours. In addition to its deleterious effects, we demonstrated that artificial exposure to oxidative stress could induce a response similar to desiccation stress, at the transcriptome and protein levels. Furthermore, the response of anhydrobiosis-related genes to desiccation and salinity stress was inhibited by antioxidant treatment. Thus, we conclude that oxidative stress is an essential trigger for inducing the expression of protective genes during the onset of anhydrobiosis in desiccating of P. vanderplanki larvae.

    DOI: 10.1016/j.mito.2023.11.002

    Scopus

    PubMed

  • Kawashima Y., Miyakoshi M., Kawabata Y., Indo H. .  Efficacy of texture analysis of ultrasonographic images in the differentiation of metastatic and non-metastatic cervical lymph nodes in patients with squamous cell carcinoma of the tongue .  Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology136 ( 2 ) 247 - 254   2023.8Reviewed

     More details

    Language:Japanese   Publisher:Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology  

    Objective: We investigated the efficacy of using texture analysis of ultrasonographic images of the cervical lymph nodes of patients with squamous cell carcinoma of the tongue to differentiate between metastatic and non-metastatic lymph nodes. Study Design: We analyzed 32 metastatic and 28 non-metastatic lymph nodes diagnosed by histopathologic examination on presurgical US images. Using the LIFEx texture analysis program, we extracted 36 texture features from the images and calculated the statistical significance of differences in texture features between metastatic and non-metastatic lymph nodes using the t test. To assess the diagnostic ability of the significantly different texture features to discriminate between metastatic and non-metastatic nodes, we performed receiver operating characteristic curve analysis and calculated the area under the curve. We set the cutoff points that maximized the sensitivity and specificity for each curve according to the Youden J statistic. Results: We found that 20 texture features significantly differed between metastatic and non-metastatic lymph nodes. Among them, only the gray-level run length matrix feature of run length non-uniformity and the gray-level zone length matrix features of gray-level non-uniformity and zone length non-uniformity showed an excellent ability to discriminate between metastatic and non-metastatic lymph nodes as indicated by the area under the curve and the sum of sensitivity and specificity. Conclusions: Analysis of the texture features of run length non-uniformity, gray-level non-uniformity, and zone length non-uniformity values allows for differentiation between metastatic and non-metastatic lymph nodes, with the use of gray-level non-uniformity appearing to be the best means of predicting metastatic lymph nodes.

    DOI: 10.1016/j.oooo.2023.04.012

    Scopus

    PubMed

  • Tomita K., Indo H.P., Sato T., Tangpong J., Majima H.J. .  Development of a sensitive double TaqMan Probe-based qPCR Angle-Degree method to detect mutation frequencies .  Mitochondrion70   1 - 7   2023.5Reviewed

     More details

    Language:Japanese   Publisher:Mitochondrion  

    We designed a method to examine the mutation frequencies of the A3243G mutation of mitochondrial DNA (mtDNA) in patients with mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome. We performed a qPCR assay using the FAM and VIC TaqMan probes, which detect the 3243G (mutated) and 3243A (wild-type) sequences of mtDNA, respectively. The results obtained by “degree” in a series of differential mutation frequencies were used to plot a standard curve of the mutation frequency. The standard curve was then applied for qPCR assays of the desired samples. The standard deviation (%) of the samples calculated using the standard curve for the TaqMan probe was 2.4 ± 1.5%. This method could be used to examine mutation frequencies in the context of diabetes, aging, cancer, and neurodegenerative diseases.

    DOI: 10.1016/j.mito.2023.02.010

    Scopus

    PubMed

  • Indo H.P., Masuda D., Sriburee S., Ito H., Nakanishi I., Matsumoto K.I., Mankhetkorn S., Chatatikun M., Surinkaew S., Udomwech L., Kawakami F., Ichikawa T., Matsui H., Tangpong J., Majima H.J. .  Evidence of Nrf2/Keap1 Signaling Regulation by Mitochodria-Generated Reactive Oxygen Species in RGK1 Cells .  Biomolecules13 ( 3 )   2023.3Reviewed

     More details

    Language:Japanese   Publisher:Biomolecules  

    It has been known that reactive oxygen species (ROS) are generated from the mitochondrial electron transport chain (ETC). Majima et al. proved that mitochondrial ROS (mtROS) caused apoptosis for the first time in 1998 (Majima et al. J Biol Chem, 1998). It is speculated that mtROS can move out of the mitochondria and initiate cellular signals in the nucleus. This paper aims to prove this phenomenon by assessing the change in the amount of manganese superoxide dismutase (MnSOD) by MnSOD transfection. Two cell lines of the same genetic background, of which generation of mtROS are different, i.e., the mtROS are more produced in RGK1, than in that of RGM1, were compared to analyze the cellular signals. The results of immunocytochemistry staining showed increase of Nrf2, Keap1, HO-1 and 2, MnSOD, GCL, GST, NQO1, GATA1, GATA3, GATA4, and GATA5 in RGK1 compared to those in RGM1. Transfection of human MnSOD in RGK1 cells showed a decrease of those signal proteins, suggesting mtROS play a role in cellular signals in nucleus.

    DOI: 10.3390/biom13030445

    Scopus

    PubMed

  • Kawashima Y, Miyakoshi M, Kawabata Y, Indo H. .  Normal Cone beam Computed Tomography image findings of nutrient canals in 340 pediatrics. .  A J Diagn imaging.9 ( 2 ) 22 - 27   2023.3Normal Cone beam Computed Tomography image findings of nutrient canals in 340 pediatrics.Reviewed

     More details

    Authorship:Last author  

  • Yusuke Kawashima, Masaaki Miyakoshi, Yoshihiro Kawabata, Hiroko. Indo. .  Value of MDCT data of mandibular condyle cancellous bone to osteoporosis screening. .  A J Diagn imaging.9 ( 1 ) 1 - 7   2023.1Value of MDCT data of mandibular condyle cancellous bone to osteoporosis screening.Reviewed

     More details

    Authorship:Last author  

  • Yusuke Kawashima, Masaaki Miyakoshi, Yoshihiro Kawabata, Hiroko Indo. .  The usefulness of intraoral ultrasonography and post-contrast three-dimensional fast field echo imaging in the evaluation of radiological depth of invasion of oral tongue squamous cell carcinoma: Comparison with pathological depth of invasion asessment. .  A J Diagn imaging.8 ( 3 ) 61 - 67   2022.12The usefulness of intraoral ultrasonography and post-contrast three-dimensional fast field echo imaging in the evaluation of radiological depth of invasion of oral tongue squamous cell carcinoma: Comparison with pathological depth of invasion asessment.Reviewed

     More details

    Authorship:Last author  

  • Indo H., Ito H., Koriyama C., Majima H.J., Shimada K., Tamatsu Y. .  Deciduous teeth development in fetuses using postmortem computed tomography image analysis .  Legal Medicine54   101969   2022.2

     More details

    Language:Japanese   Publisher:Legal Medicine  

    Fetal age is estimated widely by body length and weight and skeletal or dental development and maturation. Regarding dental development, dental development charts reported by Schour and Massler and Ubelaker are well known. We tried to calculate the calcification rate of the deciduous teeth, mandibular cortical bone, and clavicle in fetuses utilizing postmortem computed tomography (CT) image analysis. The CT values within the circumferential area of the region of interest were automatically calculated using a software, and the calcification rate was calculated by performing single regression analysis. Our results showed that deciduous tooth calcification could be detected in over 19-week-old fetuses using CT images. The calcification of bones (mandibular cortical bone and clavicle) started earlier than the calcification of deciduous teeth. However, the calcification rate of the bones was slower compared to that of the deciduous teeth. The calcification rate of the deciduous teeth in fetuses using CT value may be effective to estimate fetal age and evaluate deciduous teeth development, suggesting that our established method is effective for age estimation in forensic dentistry.

    DOI: 10.1016/j.legalmed.2021.101969

    Scopus

    PubMed

  • Kawashima usuke, Abe Hiroshi, Miyakoshi Masaaki, Kawabata Yoshihiro, Indo Hiroko, Tanaka Tatsuro .  A Case of Suspected Lymphatic Malformation in the Sublingual, Submandibular and Parapharyngeal Spaces in an Elderly Patient .  Shika Hoshasen62 ( 1 ) 47 - 50   2022

     More details

    Language:Japanese   Publisher:Japanese Society for Oral and Maxillofacial Radiology  

    DOI: 10.11242/dentalradiology.62.47

  • Kawashima Yusuke, Abe Hiroshi, Miyakoshi Masaaki, Kawabata Yoshihiro, Indo Hiroko, Tanaka Tatsuro .  A Case of Nodular Fasciitis on the Buccal Region .  Shika Hoshasen61 ( 2 ) 69 - 71   2022

     More details

    Language:Japanese   Publisher:Japanese Society for Oral and Maxillofacial Radiology  

    DOI: 10.11242/dentalradiology.61.69

  • Kawashima Yusuke, Abe Hiroshi, Miyakoshi Masaaki, Kawabata Yoshihiro, Indo Hiroko, Tanaka Tatsuro .  A Case of Foreign Body of Fish Bone in the Tongue Mimic Malignant Tumor .  Shika Hoshasen62 ( 1 ) 43 - 46   2022

     More details

    Language:Japanese   Publisher:Japanese Society for Oral and Maxillofacial Radiology  

    DOI: 10.11242/dentalradiology.62.43

  • Kawashima Yusuke, Miyakoshi Masaaki, Kawabata Yoshihiro, Indo Hiroko, Tanaka Tatsuro .  A Case of Progressive Mandibular Resorption Occurring in Bilateral Mandibular Condyles .  Shika Hoshasen61 ( 2 ) 64 - 68   2022

     More details

    Language:Japanese   Publisher:Japanese Society for Oral and Maxillofacial Radiology  

    DOI: 10.11242/dentalradiology.61.64

  • Indo H.P., Ito H., Nakagawa K., Chaiswing L., Majima H.J. .  Translocation of HSP47 and generation of mitochondrial reactive oxygen species in human neuroblastoma SK-N-SH cells following electron and X-ray irradiation .  Archives of Biochemistry and Biophysics703   108853   2021.5

     More details

    Language:Japanese   Publisher:Archives of Biochemistry and Biophysics  

    Generation of mitochondrial reactive oxygen species (ROS), lipid peroxidation, 4-hydroxy-2-nonenal, and heat-shock protein (HSP) 47 after electron and X-ray irradiations were detected in the human neuroblastoma cell line SK-N-SH. After 10 Gy electron irradiation and 15 Gy X-ray irradiation, mitochondrial ROS production and lipid peroxidation were significantly increased. Additionally, we observed a significant increase in the levels of HSP47 after 3 and 10 Gy electron irradiation as well as 15 Gy X-ray irradiation. Furthermore, myristoylation and farnesylation were increased after 10 Gy electron and 15 Gy X-ray irradiations. We found that the level of HSP47 increased in the mitochondria after 10 Gy electron and 15 Gy X-ray irradiations. HSP47 coexisted with myristoylation and farnesylation. Furthermore, HSP47 overexpression increased mitochondrial ROS production. These results suggest that HSP47 plays an important role in mitochondria and induces mitochondrial ROS production in SK-N-SH cells.

    DOI: 10.1016/j.abb.2021.108853

    Scopus

    PubMed

  • Yusuke Kawashima,Masaaki Miyakoshi, Yoshihiro Kawabata, Hiroko Indo. .  Usefulness of post-contrast three-dimensional Fast Field Echo imaging compared with Dixon T2-weighted imaging for evaluation of radiological depth of invasion in oral tongue squamous cell carcinoma: Comparison with pathological depth invasion assessment. .  A J Diagn imaging. 7 ( 3 ) 13 - 20   2021.1 Usefulness of post-contrast three-dimensional Fast Field Echo imaging compared with Dixon T2-weighted imaging for evaluation of radiological depth of invasion in oral tongue squamous cell carcinoma: Comparison with pathological depth invasion assessment.Reviewed

     More details

    Authorship:Corresponding author   Language:English  

  • Kawashima Yuusuke, Hara Yoshinobu, Tokunaga Satoshi, P. Indo Hiroko, Kaneda Takashi .  A Case of Rosai-Dorfman Disease of the Left Submandibular Gland .  Shika Hoshasen60 ( 2 ) 63 - 65   2021

     More details

    Language:Japanese   Publisher:Japanese Society for Oral and Maxillofacial Radiology  

    DOI: 10.11242/dentalradiology.60.63

  • Maezawa H, Indo HP, Usami N, Majima HJ, Ito H, Ohnishi K, Kobayashi K. .  Enhancement of membrane lipid peroxidation in lung cancer cells irradiated with monoenergetic X-rays at the K-shell resonance absorption peak of phosphorus. .  J Radiat Res.61 ( 2 ) 237 - 242   2020Enhancement of membrane lipid peroxidation in lung cancer cells irradiated with monoenergetic X-rays at the K-shell resonance absorption peak of phosphorus.Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Matsumoto K, Ueno M, Nakanishi I, Indo HP and Majima HJ. .  Effects of low-dose X-ray irradiation on melanin-devived radicals in mouse hair and skin. .  J Clin Biochem Nutr. 67 ( 2 ) 1 - 5   2020Effects of low-dose X-ray irradiation on melanin-devived radicals in mouse hair and skin.Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • 3) Ito H, Kurokawa H, Suzuki H, Indo HP, Majima HJ, Matsui H. .  5-Aminolevulinic acid induced apoptosis via oxidative stress in normal gastric epithelial cells. .  J Clin Biochem Nutr. 65 ( 2 ) 83 - 90   20195-Aminolevulinic acid induced apoptosis via oxidative stress in normal gastric epithelial cells. Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Ken-ichiro Matsumoto, Yukihiro Ogawa, Masato Kamibayashi, Minako Nyui, Ikuo Nakanishi, Shigeaki Suenaga, Hiromu Ito, Hirofumi Matsui, Toshihiko Ozawa, Hiroko P. Indo, Hideyuki J. Majima .  Assessment of Redox Status in Commercial Bottled Mineral Water .  Journal of Clinical Nutrition and Food Science1 ( 1 ) 29 - 34   2018.10Assessment of Redox Status in Commercial Bottled Mineral WaterReviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Ishida T, Hijioka H, Kume K, Yoshimura T, Miyawaki A, Nozoe E, Suenaga S, Indo H, Majima HJ, Nakamura N. .  A diagnosis system for detecting cervical lymph node metastasis inoral squamous cell carcinoma: Collective consideration of the results of multiple imaging modalities. .  J Oral Maxillofac Surg Med Pathol29   210 - 216   2017.5A diagnosis system for detecting cervical lymph node metastasis inoral squamous cell carcinoma: Collective consideration of the results of multiple imaging modalities.Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Hiroko P. Indo, Clare L Hawkins, Ikuo Nakanishi, Ken-ichiro Matsumoto, Hirofumi Matsui, Shigeaki Suenaga, Michael J. Davies, Daret K. St Clair, Toshihiko Ozawa, Hideyuki J. Majima .  Role of Mitochondrial Reactive Oxygen Species in the Activation of Cellular Signals, Molecules, and Function .  Handbook of Experimental Pharmacology   2017Role of Mitochondrial Reactive Oxygen Species in the Activation of Cellular Signals, Molecules, and FunctionReviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)   Publisher:Springer International Publishing AG  

    DOI: 10.1007/164_2016_117

  • Indo HP, Majima HJ, Terada M, Suenaga S, Tomita K, Yamada S, Higashibata A, Ishioka N, Kanekura T, Nonaka, Hawkins CL, Davies MJ, Clair DK, Mukai C .  Changes in mitochondrial homeostasis and redox status in astronauts following long stays in space .  Scientific Reports6 ( 39015 )   2016.12Changes in mitochondrial homeostasis and redox status in astronauts following long stays in spaceReviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1038/srep39015

  • Majima HJ, Indo HP, Nakanishi I, Suenaga S, Matsumoto K, Matsui H, Minamiyama Y, Ichikawa H, Yen H-C, Hawkins CL, Davies MJ, Ozawa T, St Clair DK. .  Chasing Great Paths of Helmut Sies “Oxidative Stress”. .  Arch Biochem Biophys.595   54 - 60   2016.4Chasing Great Paths of Helmut Sies “Oxidative Stress”.Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Suenaga S, Nagayama K. Nagasawa T. Kawabata Y,Indo H, Majima HJ. .  Evaluation of the relationship between contrast-enhanced magnetic resonance characteristics and joint pain in patients with temporomandibular disorders. .  Oral Radiol32 ( 2 ) 87 - 97   2016.3Evaluation of the relationship between contrast-enhanced magnetic resonance characteristics and joint pain in patients with temporomandibular disorders.Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Ito M, Matsui H, Hirayama A, Indo HP, Majima HJ, Hyodo I. .  Reactive oxygen species induced by non-steroidal anti-inflammatory drugs enhance the effects of photodynamic therapy in gastric cancer cells. .  JCBN58 ( 3 ) 180 - 185   2016.2Reactive oxygen species induced by non-steroidal anti-inflammatory drugs enhance the effects of photodynamic therapy in gastric cancer cells.Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Maeda, K, Kawai H, Sanada M, Terashima T, Ogawa N, Idehara, R, Makiishi T, Yasuda H, Sato S, Hoshi K, Yahikozawa H, Nishi K, Itoh Y, Ogasawara K, Tomita T, Indo HP, Majima HJ. .  Similar clinical phenotype and segregation of mitochondrial 3243A>G mutation in two pairs of monozygotic twins. .  JAMA Neurology   2016Similar clinical phenotype and segregation of mitochondrial 3243A>G mutation in two pairs of monozygotic twins.Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • 川畑義裕、長澤大成、守山泰司、野添悦郎、河野一典、末永重明、犬童寛子、中村典史、仙波伊知郎、馬嶋秀行 .  MRIにて“おはじき(Marble)”様の典型的所見を呈した類皮嚢胞 .  歯科放射線   2016MRIにて“おはじき(Marble)”様の典型的所見を呈した類皮嚢胞Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Indo HP, Tomiyoshi T, Suenaga S, Tomita K, Suzuki H, Masuda D, Terada M, Ishioka N, Gusev O, Cornette R, Okuda T, Mukai C, Majima HJ .  MnSOD downregulation induced by extremely low 0.1 mGy single and fractionated X-rays and microgravity treatment in human neuroblastoma cell line, NB-1 .  J Clin Biochem Nutr. 57 ( 2 ) 98 - 104   2015.9MnSOD downregulation induced by extremely low 0.1 mGy single and fractionated X-rays and microgravity treatment in human neuroblastoma cell line, NB-1Reviewed

     More details

    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  • Indo HP, Matsui H, Chen J, Zhu H, Hawkins CL, Davies MJ, Yarana C, St Clair DK, Majima HJ. .  Manganese superoxide dismutase promotes interaction of actin, S100A4 and Talin, and enhances rat gastric tumor cell invasion .  J Clin Biochem Nutr. 57 ( 1 ) 13 - 20   2015.7Manganese superoxide dismutase promotes interaction of actin, S100A4 and Talin, and enhances rat gastric tumor cell invasionReviewed

     More details

    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  • Indo HP, Yen H-C, Nakanishi I, Matsumoto K, Tamura M, Nagano Y, Matsui H, Gusev RO, Cornette R, Okuda T, Minamiyama Y, Ichikawa H, Suenaga S, Oki M, Sato T, Ozawa T, St, Clair DK, Majima HJ .  A Mitochondrial Superoxide Theory for Oxidative Stress Diseases and Aging. .  J Clin Biochem Nutr. 56 ( 1 ) 1 - 7   2015.1A Mitochondrial Superoxide Theory for Oxidative Stress Diseases and Aging.Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Ito H, Matsui H, Tamura M, Majima HJ, Indo HP, Hyodo I. .  Mitochondrial reactive oxygen species accelerate the expression of heme carrier protein 1 and enhance photodynamic cancer therapy effect. .  J Clin Biochem Nutr. 55 ( 1 ) 67 - 71   2014.7Mitochondrial reactive oxygen species accelerate the expression of heme carrier protein 1 and enhance photodynamic cancer therapy effect.Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Ito H, Tamura M, Matsui H, Majima HJ, Indo HP, Hyodo I. .  Reactive oxygen species involved cancer cellular specific 5-aminolevulinic acid uptake in gastric epithelial cells. .  J Clin Biochem Nutr54 ( 2 ) 81 - 85   2014.3Reactive oxygen species involved cancer cellular specific 5-aminolevulinic acid uptake in gastric epithelial cells. Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Tamura M, Matsui H, Nagano YN, Kaneko T, Indo HP, Majima HJ, Hyodo I .  Salt is an oxidative stressor for gastric epithelial cells. .  J Physiol Pharmacol.64 ( 1 ) 89 - 94   2014.2Salt is an oxidative stressor for gastric epithelial cells. Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Tamura M, Matsui H, Tomita T, Sadakata H, Indo HP, Majima HJ, Kaneko T, Hyodo I. .  Mitochondrial reactive oxygen species accelerate gastric cancer cell invasion .  Journal of Clinical Biochemistry and Nutrition54 ( 1 ) 12 - 17   2014.1Mitochondrial reactive oxygen species accelerate gastric cancer cell invasionReviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Nakanishi-Ueda T, Majima HJ, Watanabe K, Ueda T, Indo HP, Suenaga S, Hisamitsu T, Ozawa T, Yasuhara H, Koide R .  Blue LED light exposure develops intracellular reactive oxygen species, lipid peroxidation, and subsequent cellular injuries in cultured bovine retinal pigment epithelial cells. .  Free Radic Res.47 ( 10 ) 774 - 780   2013.10Blue LED light exposure develops intracellular reactive oxygen species, lipid peroxidation, and subsequent cellular injuries in cultured bovine retinal pigment epithelial cells. Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Haraguchi M, Indo HP, Iwasaki Y, Iwashita Y, Fukushige T, Majima HJ, Izumo K, Horiuchi M, Kanekura T, Furukawa T, Ozawa M. .  Snail modulates cell metabolism in MDCK cells. .  Biochem Biophys Res Commun.432 ( 4 ) 618 - 625   2013.5Snail modulates cell metabolism in MDCK cells. Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Indo HP, Nakanishi I, Ohkubo K, Yen H-C, Nyui M, Manda S, Matsumoto K, Fukuhara K, Anzai K, Ikota N, Matsui H, MinamiyamaY, Nakajima A, Ichikawa H, Fukuzumi S, Ozawa T, Mukai C and Majima HJ .  Comparison of in vivo and in vitro antioxidative parameters for eleven food factors. .  RSC advances3 ( 14 ) 4535 - 4538   2013.2Comparison of in vivo and in vitro antioxidative parameters for eleven food factors.Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Matsui H, Nagano Y, Shimokawa O, Kaneko T, Rai K, Udo J, Hirayama A, Nakamura Y, Indo HP, Majima HJ, Hyodo I. .  Gastric acid induces mitochondrial superoxide production and lipid peroxidation in gastric epithelial cells. .  J Gastroenterol46 ( 10 ) 1167 - 1176   2012.10Gastric acid induces mitochondrial superoxide production and lipid peroxidation in gastric epithelial cells.Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Indo HP, Inanami O, Koumura T, Suenaga S, Yen HC, Kakinuma S, Matsumoto K, Nakanishi I, St Clair W, St Clair DK, Matsui H, Cornette R, Gusev O, Okuda T, Nakagawa Y, Ozawa T, Majima HJ. .  Roles of mitochondria-generated reactive oxygen species on X-ray-induced apoptosis in a human hepatocellular carcinoma cell line, HLE. .  Free Radic Res.46 ( 8 ) 1029 - 1943   2012.8Roles of mitochondria-generated reactive oxygen species on X-ray-induced apoptosis in a human hepatocellular carcinoma cell line, HLE.Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Nagano Y, Matsui H, Shimokawa O, Hirayama A, Tamura M, Nakamura Y, Kaneko T, Rai K, Indo HP, Majima HJ, Hyodo I. .  Rebamipide attenuates nonsteroidal anti-inflammatory drugs (NSAID) induced lipid peroxidation by the manganese superoxide dismutase (MnSOD) overexpression in gastrointestinal epithelial cells. .  J Physiol Pharmacol.63 ( 2 ) 137 - 142   2012.4Rebamipide attenuates nonsteroidal anti-inflammatory drugs (NSAID) induced lipid peroxidation by the manganese superoxide dismutase (MnSOD) overexpression in gastrointestinal epithelial cells. Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Majima HJ, Indo HP, Suenaga S, Matsui H, Yen H-C and Ozawa T .  Mitochondria as Possible Pharmaceutical Targets for the Effects of Vitamin E and its Homologues in Oxidative Stress-Related Diseases. .  Curr Pharm Des.17 ( 21 ) 2190 - 2195   2012.1Mitochondria as Possible Pharmaceutical Targets for the Effects of Vitamin E and its Homologues in Oxidative Stress-Related Diseases. Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Rai K, Matsui H, Kaneko T, Nagano Y, Shimokawa O, Udo J, Hirayama A, Hyodo I, Indo HP, Majima HJ. .  Lansoprazole inhibits mitochondrial superoxide production and cellular lipid peroxidation induced by indomethacin in RGM1 cells. .  J Clin Biochem Nutr.49 ( 1 ) 25 - 30   2011.1Lansoprazole inhibits mitochondrial superoxide production and cellular lipid peroxidation induced by indomethacin in RGM1 cells.Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Hideyuki J. Majima, Hiroko P. Indo, Kazuo Tomita, Yoichiro Iwashita, Hiromi Suzuki, Daisuke Masuda, Toru Shimazu, Fumiaki Tanigaki, Sayaka Umemura, Sachiko Yano, Kei Fukui, Akira Higashibata, Takashi Q Yamazaki, Masaki Kameyama, Shigeaki Suenaga, Tsuyoshi Sato, Hsiu-Chuan Yen, Oleg Gusev, Takashi Okuda, Hirofumi Matsui, Toshihiko Ozawa, Noriaki Ishioka .  Bio-Assessment of RISK in Long-Term Manned Space Exploration - Cell Death Factors in Space Radiation and/or Microgravity: A Review- .  Biological Sciences in Space23 ( 2 ) 43 - 53   2009.9Bio-Assessment of RISK in Long-Term Manned Space Exploration - Cell Death Factors in Space Radiation and/or Microgravity: A Review-Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • NONG Qingqing, KOMATSU Masaharu, IZMO Kimiko,INDO Hiroko P., Xu Baohui, AOYAMA Koichi, MAJIMA Hideyuki J., HORIUCHI Masahisa, MORIMOTO Kanehisa, TAKEUCHI Toru .  Involvement of reactive oxygen species in Microcystin-LR-induced cytogenotoxicity .  Free Radic Res41 ( 12 ) 1326 - 1337   2007.12Involvement of reactive oxygen species in Microcystin-LR-induced cytogenotoxicityReviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • INDO Hiroko P., Davidson M, Yen H-C, SUENAGA Shigeaki, TOMITA Kazuo, Nishii T, Higuchi M, Koga Y, Ozawa T, MAJIMA Hideyuki J. .  Evidence of ROS generation by mitochondria in cells with impaired electron transport chain and mitochondrial DNA damage. .  Mitochondrion7 ( 1月2日 ) 106 - 118   2007.2Evidence of ROS generation by mitochondria in cells with impaired electron transport chain and mitochondrial DNA damage.Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • INDO Hiroko P., SUENAGA Shigeaki, NOZOE Etsuro, NAKAMURA Norifumi, TANUMA Jun-ichi , SEMBA Ichiro, MAJIMA Hideyuki J. .  Pleomorphic adenoma presenting low T2 signal-intensity on magnetic resonance imaging. .  Dentomaxillofac Radiol.35 ( 5 ) 380 - 382   2006.9Pleomorphic adenoma presenting low T2 signal-intensity on magnetic resonance imaging.Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • SATO Tsuyoshi, KAWABATA Yoshihiro, Saigo Y, IWASHITA Yoichiro, SUENAGA Shigeaki, INDO Hiroko P., HAMAHIRA Sumiko, KAWANO Kazunori, Nitta T, MORITA Yasuhiko, MAJIMA Hideyuki J., SUGIHARA Kazumasa .  Interpretation of scintigraphic findings of oral malignant tumours with a new scanning agent of technetium-99m-hexakis-2-methoxy-isobutyl-isonitrile (Tc-99m-MIBI) .  Dentomaxillofacial Radiology B.I.R.35 ( 1 ) 24 - 295   2006.1Interpretation of scintigraphic findings of oral malignant tumours with a new scanning agent of technetium-99m-hexakis-2-methoxy-isobutyl-isonitrile (Tc-99m-MIBI)Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • SATO Tsuyoshi, KAWABATA Yoshihiro, Nitta T, Saigo Y, IWASHITA Yoichiro, SUENAGA Shigeaki, HAMAHIRA Sumiko, INDO Hiroko P., MORITA Yasuhiko, MAJIMA Hideyuki J., SUGIHARA Kazumasa .  Expression of permeability-glycoprotein (P-gp) and uptake of technetium-99m-hexakis-2-methoxy-isobutyl-isonitrile (Tc-MIBI) in malignant tumour of the head and neck .  Dentomaxillofacial Radiology B.I.R.34 ( 5 ) 274 - 278   2005.9Expression of permeability-glycoprotein (P-gp) and uptake of technetium-99m-hexakis-2-methoxy-isobutyl-isonitrile (Tc-MIBI) in malignant tumour of the head and neckReviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • SATO Tsuyoshi, KAWABATA Yoshihiro, SUENAGA Shigeaki,INDO Hiroko P., KAWANO Kazunori, IWASHITA Yoichiro, MORITA Yasuhiko, MAJIMA Hideyuki J. .  Scintigraphy for interpretation of malignant tumours of the head and neck: comparison of technetium-99m-hexakis-2-methoxyisobutylisonitrile (Tc-MIBI) and thallium-201-chloride (Tl-201) .  Dentomaxillofacial Radiology B.I.R.34 ( 5 ) 268 - 273   2005.9Scintigraphy for interpretation of malignant tumours of the head and neck: comparison of technetium-99m-hexakis-2-methoxyisobutylisonitrile (Tc-MIBI) and thallium-201-chloride (Tl-201)Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • KAWATOKO Seigo, SATO Tsuyoshi, KAWABATA Yoshihiro, SUENAGA Koichi, SUENAGA Shigeaki,MORITA Yasuhiko, INDO Hiroko P., KAWANO Kazunori, IWASHITA Yoichiro, Majima HJ, SUGIHARA Kazumasa, SEMBA Ichiro .  A trial for histopathological subclassification of papillary cystadenoma lymphomatosum by Tc-pertechnetate in a patient with multiple bilateral lesions of the parotid glands .  Dentomaxillofacial Radiology B.I.R.34 ( 4 ) 218 - 221   2005.7A trial for histopathological subclassification of papillary cystadenoma lymphomatosum by Tc-pertechnetate in a patient with multiple bilateral lesions of the parotid glandsReviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • SATO Tsuyoshi, INDO Hiroko P., KAWABATA Yoshihiro, Kobayashi T, SUENAGA Shigeaki, IWASHITA Yoichiro, Nitta T, SUGIHARA Kazumasa, MAJIMA Hideyuki J. .  Thallium-201 chloride (TL-201) accumulation and Na/K-ATPase expression in tumours of the head and neck .  Dentomaxillofacial Radiology B.I.R.34 ( 4 ) 212 - 217   2005.7Thallium-201 chloride (TL-201) accumulation and Na/K-ATPase expression in tumours of the head and neckReviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Hirai F, Motoori S, Kakinuma S, TOMITA Kazuo, INDO Hiroko P., Kato H, Yamaguchi T, Yen HC, St Clair DK, Nagano T, Ozawa T, Saisho H, MAJIMA Hideyuki J. .  Mitochondrial Signal Lacking Manganese Superoxide Dismutase Failed to Prevent Cell Death by Reoxygenation Following Hypoxia in a Human Pancreatic Cancer Cell Line, KP4 .  Antioxidants & Redox Signaling6 ( 3 ) 523 - 535   2004.6Mitochondrial Signal Lacking Manganese Superoxide Dismutase Failed to Prevent Cell Death by Reoxygenation Following Hypoxia in a Human Pancreatic Cancer Cell Line, KP4Reviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • 犬童寛子, 森田康彦, 末永重明, 上島一男, 早渕正史, 馬嶋秀行 .  写真供覧 耳下腺炎2症例のMR hydrography所見 .  歯科放射線42 ( 1 ) 48 - 49   2002.3写真供覧 耳下腺炎2症例のMR hydrography所見Reviewed

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)  

  • 犬童寛子 .  顎顔面頸部領域におけるCT-Angiographyの実用化に対する実験的検討 .  歯科放射線42 ( 1 ) 22 - 32   2002.3顎顔面頸部領域におけるCT-Angiographyの実用化に対する実験的検討Reviewed

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)  

  • 森田康彦,誉田栄一,犬童寛子,加藤二久,原田康雄,河野一典,佐藤強志,馬嶋秀行,和泉雄一,佐々木武仁,野井倉武憲. .  歯科インプラント治療計画の画像診断のための高速らせんCT撮影条件の画質に与える影響評価:半解剖学的下顎ファントムによる視覚的検討 .  歯科放射線42 ( 4 ) 259 - 273   2002歯科インプラント治療計画の画像診断のための高速らせんCT撮影条件の画質に与える影響評価:半解剖学的下顎ファントムによる視覚的検討Reviewed

  • Sato T, Indo H, Takasaki T, Kawabata Y, Morita Y and Noikura T. .  A rare case of intraosseous polymorphous low-grade adenocarcinoma (PLGA) of the maxilla. .  Dentomaxillofacial Radiology30 ( 3 ) 184 - 187   2001A rare case of intraosseous polymorphous low-grade adenocarcinoma (PLGA) of the maxilla.

  • 佐藤 強志,川畑 義裕,犬童 寛子,森田 康彦,川床 正剛,河野 一典,末永 重明,野井倉 武憲 .  舌根部に見られた骨性あるいは軟骨性分離腫の1例 .  歯科放射線41 ( 1 ) 52 - 52   2001舌根部に見られた骨性あるいは軟骨性分離腫の1例

  • Sato T, Indo H, Kawabata Y, Agarie R, Ishigami T, Noikura T. .  Scintigraphic evaluation of chronic osteomyelitis of the mandible in SAPHO syndrome .  Dentomaxillofac Radiology30 ( 5 ) 293 - 295   2001Scintigraphic evaluation of chronic osteomyelitis of the mandible in SAPHO syndromeReviewed

  • 森田康彦,誉田栄一,吉野教夫,加藤二久,河野一典,犬童寛子,佐々木武仁, 野井倉武憲. .  高速らせんCT検査における患者被曝線量の低減 .  歯科放射線40 ( 3 ) 187 - 199   2000高速らせんCT検査における患者被曝線量の低減Reviewed

  • Hiroko Indo,Tsuyoshi Sato, Takenori Noikura .  A case of Hereditary Cherubism .  Oral Radiol.15 ( 1 ) 37 - 42   1999.6A case of Hereditary CherubismReviewed

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • 佐藤強志,長井講有,森田康彦,犬童寛子,河野一典,野井倉武憲 .  顎・顔面領域悪性腫瘍の診断における塩化タリウムシンチの有用性についての検討ー腫瘍組織分化度,浸潤度とRetention Indexの関係についてー .  歯科放射線39 ( 3 ) 147 - 158   1999顎・顔面領域悪性腫瘍の診断における塩化タリウムシンチの有用性についての検討ー腫瘍組織分化度,浸潤度とRetention Indexの関係についてーReviewed

  • 森田康彦,犬童寛子,野井倉武憲 .  顎顔面領域のCT-Angiographyにおける造影並びに撮像条件ー血管並びに腫瘍の同時摘出のための1相法の検討ー .  歯科放射線39 ( 3 ) 159 - 162   1999顎顔面領域のCT-Angiographyにおける造影並びに撮像条件ー血管並びに腫瘍の同時摘出のための1相法の検討ーReviewed

  • 犬童寛子, 牧正啓, 大林武久, 太田和俊, 田縁昭 .  腫瘍性病変を疑った歯肉増殖の1例 .  熊本医学会雑誌72 ( 1 ) 59 - 64   1988.9腫瘍性病変を疑った歯肉増殖の1例Reviewed

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)  

▼display all

Books

  • Mitochondria as Source of Free Radicals.

    Hideyuki J. Majima, Hiroko P. Indo, Shigeaki Suenaga, Tsuyoshi Kaneko, Hirofumi Matsui, Hsiu-Chuan Yen, Toshihiko Ozawa( Role: Joint author)

    Naito Y, Suematsu M, Yoshikawa T (eds): Free Radical Biology in Digestive Diseases, Front Gastrointest Res. Basel, Karger  2011.1 

     More details

    Language:English Book type:Scholarly book

  • セメント芽細胞腫

    馬嶋秀行、犬童寛子( Role: Joint author)

    日本歯科放射線学会編 歯科臨床における画像診断アトラス、医歯薬出版株式会社  2008.1 

     More details

    Language:Japanese Book type:Scholarly book

  • Intracellular oxidative stress caused by ionizing radiation

    MAJIMA Hideyuki J., INDO Hiroko P., TOMITA Kazuo, SUENAGA Shigeaki, Motoori S, Kato H, Yen H-C, Ozawa T( Role: Joint author)

    Oxidative Stress, Disease and Cancer, ed. Singh K., Imperial College Press, London, UK  2006.1 

     More details

    Language:English Book type:Scholarly book

MISC

  • 多彩な進展様式が混在した上顎粘表皮癌の1例

    宮腰 昌明, 阿部 浩志, 萩元 綾, 川島 雄介, 川畑 義裕, 犬童 寛子, 比地岡 浩志, 嶋 香織, 杉浦 剛, 笹平 智則, 田中 達朗

    歯科放射線   63 ( 1 )   20 - 24   2023.9

     More details

    Language:Japanese   Publisher:(NPO)日本歯科放射線学会  

  • Promising effects of an online studying abroad program with cultural exchange

    Heima M., Ying-Chu L., Miura H., Indo H., Nishitani Y.

    Journal of Dental Education   86 ( S1 )   787 - 788   2022.6

     More details

    Language:Japanese   Publisher:Journal of Dental Education  

    DOI: 10.1002/jdd.12808

    Scopus

    PubMed

  • 国際宇宙ステーション「きぼう」におけるヒト神経細胞宇宙実験「Neuro Rad」

    馬嶋秀行・犬童寛子

    県歯科医師会報   91 ( 670 )   8 - 10   2010.1

     More details

    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

  • ミトコンドリア・アポトーシスと酸化ストレス

    馬嶋秀行、犬童寛子、富田和男、松井裕史、小澤俊彦

    酸化ストレスの医学、吉川敏一監修、内藤裕二、豊國伸哉編集、診断と治療社、東京   81 - 87   2008.1

     More details

    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

  • MnSODによるラット胃癌細胞RGK1における酸化ストレス誘導蛋白発現抑制調節 Reviewed

    犬童寛子、富田和男、馬嶋秀行

    G.I.Research   16 ( 4 )   90 - 91   2008.1

     More details

    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

  • 放射線感受性におけるミトコンドリアの役割 Reviewed

    犬童寛子、富田和男、松井裕史、小澤俊彦、馬嶋秀行

    放射線生物研究   42 ( 4 )   416 - 427   2007.1

     More details

    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

▼display all

Presentations

  • Hiromu Ito, Rodrigo Demian Naranjo, Hiroko P. Indo, Junko Tanaka, Yoshihiro Miwa, Hirofumi Matsui and Hideyuki J. Majima   Existence of Progerin inside Mitochondria in Cells of Hutchinson-Gilford Progeria Syndrome   International conference

    the 9th Biennial Meeting of Society for Free Radical Research Asia (SFRR-Asia 2019)  the 9th Biennial Meeting of Society for Free Radical Research Asia (SFRR-Asia 2019)

     More details

    Event date: 2019.4

    Language:English   Presentation type:Poster presentation  

  • 伊藤紘、Naranjo Rodrigo Demian、犬童寛子、田中順子、三輪佳宏、松井裕史、馬嶋秀行   ハッチンソンギルフォードプロジェリア症候群に対するミトコンドリアの寄与  

    第37回Cytoprotection研究会  第37回Cytoprotection研究会

     More details

    Event date: 2019.3

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

  • 伊藤紘、寺崎正彦、黒川宏美、犬童寛子、馬嶋秀行、松井裕史   酢酸による光線力学療法増強効果の検討  

    第37回Cytoprotection研究会  第37回Cytoprotection研究会

     More details

    Event date: 2019.3

    Language:Japanese   Presentation type:Oral presentation (general)  

  • Hiromu Ito, Hiromi Kurokawa, Aki Hirayama, Hiroko P. Indo, Hideyuki J. Majima and Hirofumi Matsui   Mitochondrial reactive oxygen species regulate the expression of non-heme iron transporter and promote iron incorporation in gastric cancer cells   International conference

    ASCB/EMBO 2018 meeting  ASCB/EMBO 2018 meeting

     More details

    Event date: 2018.12

    Language:English   Presentation type:Poster presentation  

  • 伊藤紘、Naranjo Rodrigo Demian、犬童寛子、馬嶋秀行   早老疾患の発症に対するミトコンドリアの寄与  

    第18回日本ミトコンドリア学会年会  第18回日本ミトコンドリア学会年会

     More details

    Event date: 2018.12

    Language:Japanese   Presentation type:Oral presentation (general)  

  • Hiromu Ito, Hiromi Kurokawa, Aki Hirayama, Hiroko P. Indo, Hideyuki J. Majima and Hirofumi Matsui   Reactive oxygen species derived from mitochondria increase non-heme iron incorporation in gastric cancer cells by regulating the expression of transporters   International conference

    The Society for Redox Biology and Medicine's 25th Annual Conference (SfRBM 2018)  The Society for Redox Biology and Medicine's 25th Annual Conference (SfRBM 2018)

     More details

    Event date: 2018.11

    Language:English   Presentation type:Poster presentation  

  • Hideyuki J Majima, Hiroko P Indo, Hiromu Ito, Hirofumi Matsui   Role of ROS generated from mitochondria on activation of cellular signals   International conference

    10th International Symposium on Cell/Tissue Injury and Cytoprotection/Organo- protection (10th ISCTICO 2018)  10th International Symposium on Cell/Tissue Injury and Cytoprotection/Organo- protection (10th ISCTICO 2018)

     More details

    Event date: 2018.6

    Language:English   Presentation type:Oral presentation (general)  

  • Hiroko P. Indo, Shigeaki Suenaga, Kazuo Tomita, Hiromi Ito, Hirofumi Matsui and Hideyuki J. Majima   Analysis of Oxidative Stress Marker, mitochondrial DNA copy numbers and Mitochondrial DNA Oxidation among 135 persons who live in Amami islands, high centenarian population District in Kagoshima   International conference

    19th Biennial Meeting of Society for Free Radical Research International (SFRRI 2018)  19th Biennial Meeting of Society for Free Radical Research International (SFRRI 2018)

     More details

    Event date: 2018.6

    Language:English   Presentation type:Poster presentation  

  • Hideyuki J Majima, Hiroko P Indo, Hiromu Ito, Hirofumi Matsui   Do ROS Generated from Mitochondria Regulate Cellular Signals?   International conference

    International Organelle Conference on Subcellular Organelles 2018  International Organelle Conference on Subcellular Organelles 2018

     More details

    Event date: 2018.5

    Language:English   Presentation type:Oral presentation (invited, special)  

  • Hiroko P. Indo, Chizuru Tsuruoka, Shizuko Kakinuma, Hirofumi Matsui, and Hideyuki J. Majima   Rho0 cells are susceptible to X-irradiation-induced cellular injury   International conference

    SFRBM'S 21th Annual Meeting  SFRBM'S 21th Annual Meeting

     More details

    Event date: 2014.11

    Language:English  

    Venue:Seattle, USA  

    国際学会

  • Shigeaki Suenaga, Hiroko P Indo, Hsiu-Chuan Yen, Hirofumi Matsui, Toshihiko Ozawa, Hideyuki J Majima,   Induction of mitochondrial ROS and cell death by cytokines and its prevention by estrogen in rheumatoid arthritis   International conference

    17th Biennial Meeting of Society for Free Radical Research International  17th Biennial Meeting of Society for Free Radical Research International

     More details

    Event date: 2014.3

    Language:English  

    Venue: Kyoto Japan  

    国際学会

  • Hiroko P. Indo, Chizuru Tsuruoka, Shizuko Kakinuma, Masao Suzuki, Ken-ichiro Matsumoto, Ikuo Nakanishi, Hsiu-Chuan Yen, Hirofumi Matsui, Toshihiko Ozawa, and Hideyuki J. Majima   Rho0 cells are susceptible to X-irradiation.   International conference

    The 32nd Annual Meeting of the Japanese Society for Cytoprotection & Cytobiology  The 32nd Annual Meeting of the Japanese Society for Cytoprotection & Cytobiology

     More details

    Event date: 2014.3

    Language:English  

    Venue:京都  

    国際学会

  • Hiroko P. Indo, Hirofumi Matsui, Hsiu-Chuan Yen, Toshihiko Ozawa, Aaron K Holly, Daret K St. Clair and Hideyuki J. Majima   Quercetin Induced Starvation-like Condition Followed by Autophagy in Rat Gastric Tumor Cells.   International conference

    SFRBM'S 20th Annual Meeting  SFRBM'S 20th Annual Meeting

     More details

    Event date: 2013.11

    Language:English  

    Venue:San Antonio, USA  

    国際学会

  • Hideyuki Majima, Ken-Ichiro Matsumoto, Hiroko Indo, Yoshihiro, Kawabata, Tomoko Fukushige, Takuro Kanekura, Akihide Tanimoto, Masahiro Terada, Akira Higashibata, Noriaki Ishioka, Aiko Nagamatsu, Hiromi Suzuki, Daisuke Masuda, Yoshinobu Ohira, Betty Nusgens, Shin Yamada, Hiroshi Ohshima, Chiaki Mukai   Effects of Space Environment on cells of the outer sheath of mouse skin hair:A comparison with the effects of x-irradiation   International conference

    19th IAA Humans in Space Symposium  19th IAA Humans in Space Symposium

     More details

    Event date: 2013.7

    Language:English  

    Venue:Cologne, Germany  

    国際学会

  • 末永重明,永山邦宏,犬童寛子,宮脇正一,中村典史,馬嶋秀行   顎関節症における咀嚼筋部疼痛に対する脳賦活部位のfMRI解析  

    第67回 NPO法人日本口腔科学会学術大会.  第67回 NPO法人日本口腔科学会学術大会.

     More details

    Event date: 2013.5

    Language:Japanese  

    Venue:栃木  

    国内学会

  • 馬嶋秀行、犬童寛子   MnSODによるX線由来アポトーシスの抑制はそのミトコンドリア局在を必要とする  

    第57回(社)日本口腔外科学会総会・学術大会  第57回(社)日本口腔外科学会総会・学術大会

     More details

    Event date: 2012.10

    Language:Japanese  

    Venue:横浜  

    国内学会

  • Hiroko P. Indo, Hideyuki J. Majima   Quercetin induces starvation like condition followed by autophagy in rat gastric mucosal cells.  

    日本癌学会  日本癌学会

     More details

    Event date: 2012.9

    Language:Japanese  

    Venue:札幌、北海道  

    国内学会

  • Hiroko P Indo, Sompong Sriburee, Samlee Mankhetkorn, Hsiu-Chuan Yen, Hirofumi Matsui, Toshihiko Ozawa , and Hideyuki J Majima   Quercetin Induced Autophagy by Starvation Simulated Condition in Rat Gastric Tumor Cell Line, RGK-1.   International conference

    The 16th Biennial Meeting of the Society for Free Radical Research - International  The 16th Biennial Meeting of the Society for Free Radical Research - International

     More details

    Event date: 2012.9

    Language:English  

    Venue:London,UK  

    国際学会

  • 馬嶋秀行、犬童寛子、松本謙一郎、福重智子、金蔵拓郎、谷本昭英、寺田昌弘、東端晃、石岡 憲昭、鈴木ひろみ、桝田大輔、大平充宣、山田深5、大島博、向井千秋   ISS搭載マウス皮膚の病理学的検討  

    第49回放射線影響懇話会  第49回放射線影響懇話会

     More details

    Event date: 2012.7

    Language:Japanese  

    Venue:北九州  

    研究会

  • 馬嶋秀行,犬童寛子,小澤俊彦   ミトコンドリア由来活性酸素とアポトーシス  

    第12回日本抗加齢医学会総会シンポジウム9「身から出た錆」  第12回日本抗加齢医学会総会シンポジウム9「身から出た錆」

     More details

    Event date: 2012.6

    Language:Japanese  

    Venue:横浜  

    国内学会

  • 田村磨聖,松井裕史,長野由美子,富田勉,貞方久人,犬童寛子,馬嶋秀行,兵頭一之介   ミトコンドリア由来活性酸素はがん浸潤を促進する  

    第65回日本ストレス学会学術集会  第65回日本ストレス学会学術集会

     More details

    Event date: 2012.6

    Language:Japanese  

    Venue:徳島  

    国内学会

  • 犬童寛子, 石岡憲昭、鈴木ひろみ、永松愛子、島津徹、矢野幸子、谷垣文章、桝田大輔、蓑部悦子、亀山正樹、馬嶋秀行   宇宙放射線および微小重力が哺乳細胞に及ぼす影響  

    第30回Cytoprotection研究会  第30回Cytoprotection研究会

     More details

    Event date: 2012.3

    Language:Japanese  

    Venue:京都  

    研究会

  • Hiroko P. Indo, Noriaki Ishioka, Hiromi Suzuki, Toru Shimazu, Sachiko Yano, Fumiaki Tanigaki, Aiko Nagamatsu, Daisuke Masuda, Etsuko Minobe, And Masaki Kameyama And Hideyuki J. Majima   Effects of 14 and 28 days exposure of human neuro cells in Space; Neuro Rad Experiments   International conference

    SFRBM's 18th Annual Meeting  SFRBM's 18th Annual Meeting

     More details

    Event date: 2011.11

    Language:English  

    Venue: Atlanta,USA  

    国際学会

  • Shigeaki Suenaga, Hiroko P. Indo, Hsiu-Chuan Yen, Kosei Ijiri, Setsuro Komiya, Takami Matsuyama, Masahiro Higuchi, Hirofumi Matsui, Toshihiko Ozawa, Hideyuki J. Majima   Induction of mitochondrial ROS and cell death by cytokines and its prevention by estrogen in rheumatoid arthritis fibroblasts   International conference

    5th Biennial Meeting of Society for Free Radical Research-Asia(SFRR-Asia),8th Conference of Asian Society for Mitochondrial Research and Medicine(ASMRM),11th Conference of Japanese Society of Mitochondrial Research and Medicine  5th Biennial Meeting of Society for Free Radical Research-Asia(SFRR-Asia),8th Conference of Asian Society for Mitochondrial Research and Medicine(ASMRM),11th Conference of Japanese Society of Mitochondrial Research and Medicine

     More details

    Event date: 2011.9

    Language:English  

    Venue:鹿児島  

    国際学会

  • Motoharu Miyamoto, Hiroko P. Indo, Kazuyuki Noguchi, Hciu-Chuan Yen, Hirofumi Matsui, Toshihiko Ozawa and Hideyuki J. Majima   Effects of Indometahcin on rat gastric normal cells RGM-1 and its tumourized cells RGK-1 and the prevention by Rebamipide   International conference

    5th Biennial Meeting of Society for Free Radical Research-Asia(SFRR-Asia),8th Conference of Asian Society for Mitochondrial Research and Medicine(ASMRM),11th Conference of Japanese Society of Mitochondrial Research and Medicine  5th Biennial Meeting of Society for Free Radical Research-Asia(SFRR-Asia),8th Conference of Asian Society for Mitochondrial Research and Medicine(ASMRM),11th Conference of Japanese Society of Mitochondrial Research and Medicine

     More details

    Event date: 2011.9

    Language:English  

    Venue:鹿児島  

    国際学会

  • 犬童寛子、石岡憲昭、鈴木ひろみ、島津徹、矢野幸子、谷垣文章、桝田大輔、蓑部悦子、亀山正樹、馬嶋秀行   宇宙放射線および微小重力が哺乳細胞に及ぼす影響  

    第64回日本酸化ストレス学会学術集会  第64回日本酸化ストレス学会学術集会

     More details

    Event date: 2011.7

    Language:Japanese  

    Venue:北海道  

    国内学会

  • 犬童寛子、Sompong Sriburee、富田和男、松井裕史、小澤俊彦、馬嶋秀行   ケルセチンによってオートファジーが誘導される  

    第64回日本酸化ストレス学会学術集会  第64回日本酸化ストレス学会学術集会

     More details

    Event date: 2011.7

    Language:Japanese  

    Venue:北海道  

    国内学会

  • Shigeaki Suenaga, Hiroko P Indo, Yoshinori Kawabata, Hideyuki J Majima   TMJ Disorders and Pain: Assessment of Synovitis by Gadolinium-Enhanced MRI   International conference

    18th International Congress of Dento-Maxillo-Facial Radiology and 52nd Annual Congress of Japanese Society for Oral and Maxillofacial Radiology (JSOMR)  18th International Congress of Dento-Maxillo-Facial Radiology and 52nd Annual Congress of Japanese Society for Oral and Maxillofacial Radiology (JSOMR)

     More details

    Event date: 2011.5

    Language:English  

    Venue:広島  

    国際学会

  • H. J. Majima, D. Masuda, A. Nagamatsu, H. P. Indo, Y. Iwashita, H. Suzuki, T. Shimazu, S. Yano, F. Tanigaki, N. Ishioka, and C. Mukai   A Study of Space Radiation Shielding Ability Using Regolith   International conference

    18th IAA Humans in Space Symposium, Houston  18th IAA Humans in Space Symposium, Houston

     More details

    Event date: 2011.4

    Language:English  

    Venue:Houston, Texas, USA  

    国際学会

  • H. J. Majima, H. P. Indo, N. Ishioka, H. Suzuki, T. Shimazu, S. Yano, F. Tanigaki, D. Masuda   28 days Space Exposure for human neuro cells, “Neuro Rad” Experiments   International conference

    18th IAA Humans in Space Symposium  18th IAA Humans in Space Symposium

     More details

    Event date: 2011.4

    Language:English  

    Venue:Houston, Texas, USA  

    国際学会

  • 馬嶋秀行、犬童寛子、石岡憲昭、鈴木ひろみ、嶋津 徹、矢野幸子、谷垣文章、桝田大輔   ISSきぼうでのヒト神経培養細胞に対する宇宙放射線研究Neuro Rad実験  

    宇宙利用シンポジウム(第27回)  宇宙利用シンポジウム(第27回)

     More details

    Event date: 2011.1

    Language:Japanese  

    Venue:相模原  

    国内学会

  • Hiroko P. Indo, Sompong Sriburee, Kazuo Tomita, Hirofumi Matsui, Hsiu-Chuan Yen, Toshihiko Ozawa and Hideyuki J. Majima   Quercetin Induced Autophagy in Rat Gastric Mucosal Cells RGM1 and Its Tumor Cells RGK1   International conference

    SFRBM’s 17th Annual Meeting  SFRBM’s 17th Annual Meeting

     More details

    Event date: 2010.11

    Language:English  

    Venue:Orlando, Florida USA  

    国際学会

  • 馬嶋 秀行, 犬童 寛子, 石岡 憲昭, 鈴木ひろみ, 島津 徹, 矢野 幸子, 谷垣 文章,桝田 大輔   「きぼう」での宇宙放射線研究Neuro Rad報告: ヒト神経培養細胞に対する宇宙環境の影響  

    日本放射線影響学会第53回大会  日本放射線影響学会第53回大会

     More details

    Event date: 2010.10

    Language:Japanese  

    Venue:京都  

    国内学会

  • 馬嶋秀行、犬童寛子、石岡憲昭、鈴木ひろみ、嶋津 徹、矢野幸子、谷垣文章、桝田大輔   Neuro Rad 実験  

    日本宇宙生物科学会第24 回大会  日本宇宙生物科学会第24 回大会

     More details

    Event date: 2010.9

    Language:Japanese  

    Venue:仙台  

    国内学会

  • 川畑義裕、河野一典、犬童寛子、末永重明、佐藤強志、仙波伊知郎、中村典史、黒野祐一、馬越瑞夫、谷本昭英、義岡孝子、米澤傑、北島信一、馬嶋秀行   上顎に発生した骨形成性粘表皮癌の画像所見  

    日本歯科放射線学会第15回臨床画像大会  日本歯科放射線学会第15回臨床画像大会

     More details

    Event date: 2010.9

    Language:Japanese  

    Venue:鹿児島  

    国内学会

  • Daisuke Masuda, Aiko Ngamatsu, Hiroko P Indo, Yoichiro Iwashita, Hiromi Suzuki, Toru Shimazu, Sachiko Yano, Fumiaki Tanigaki, Noriaki Ishioka, Chiaki Mukai, Hideyuki J Majima   Aiming Optimum Space Radiation Protection using Regolith.   International conference

    38th COSPAR Scientific Assembly  38th COSPAR Scientific Assembly

     More details

    Event date: 2010.7

    Language:English  

    Venue:Bremen, Germany  

    国際学会

  • Tsuyoshi Sato, Yoshihiro Kawabata, Kazunori Kawano, Hiroko P. Indo, Shigeaki Suenaga, H. Majima, Y. Iwashita, and K. Tomita   Scintigraphy for Oral Malignant Lesions.   International conference

    IADR (International Association for Dental Research) General Session  IADR (International Association for Dental Research) General Session

     More details

    Event date: 2010.6

    Language:English  

    Venue:Barcelona, Spain  

    国際学会

  • Shigeaki Suenaga, Hiroko P Indo, Kazuo Tomita, Kosei Ijiri, Setsuro Komiyama, Takami Matsuyama, Hsiu-Chuan Yen, Masahiro Higuchi, Hirofumi Matsui, Toshihiko Ozawa, Hideyuki J Majima   Nitric- and Oxidative Mitochondria Related Cell Death by Cytokines and its Prevention by Estrogen in Estrogen Receptor Expressed Rheumatoid Arthritis Synovial Fibroblasts.   International conference

    The 6th International Conference on the Biology, and Therapeutic Applications of Nitric Oxide  The 6th International Conference on the Biology, and Therapeutic Applications of Nitric Oxide

     More details

    Event date: 2010.6

    Language:English  

    Venue:京都  

    国際学会

  • 馬嶋 秀行、犬童 寛子、小澤 俊彦   ミトコンドリアDNA 障害と酸化ストレス  

    第10回日本抗加齢医学会総会  第10回日本抗加齢医学会総会

     More details

    Event date: 2010.6

    Language:Japanese  

    Venue:京都  

    国内学会

  • Hideyuki J Majima, Hiroko P Indo, Hsiu-Chuan Yen, Kazuo Tomita, Sompong Sriburee, Samlee Mankhetkorn, Hirofumi Matsui, and Toshihiko Ozawa   Hideyuki J Majima, Hiroko P Indo, Hsiu-Chuan Yen, Kazuo Tomita, Sompong Sriburee, Samlee Mankhetkorn, Hirofumi Matsui, and Toshihiko Ozawa   International conference

    2009 MEPSA(Mutagenesis and Experimental Pathology Society of Australlasia) Annual Scientific Meeting  2009 MEPSA(Mutagenesis and Experimental Pathology Society of Australlasia) Annual Scientific Meeting

     More details

    Event date: 2009.12

    Language:English  

    Venue:オーストラリア  

    国際学会

  • 馬嶋 秀行、犬童 寛子、富田 和男、岩下洋一朗、鈴木 ひろみ、桝田 大輔、嶋津 徹、東端 晃、山崎 丘、矢野 幸子、石岡 憲昭   ヒト神経細胞における微小放射線被曝による遺伝子変化.  

    日本放射線影響学会第52回大会  日本放射線影響学会第52回大会

     More details

    Event date: 2009.11

    Language:Japanese  

    Venue:広島  

    国内学会

  • Hideyuki J Majima, Hiroko P Indo, Hsiu-Chuan Yen, Kazuo Tomita, Sompong Sriburee, Samlee Mankhetkorn, Hirofumi Matsui, and Toshihiko Ozawa   Control of Nrf2/Keap1 Signaling by Mitochondrial Generated Reactive Oxygen Species.   International conference

    4th Cell Stress Society International (CSSI) Congress on Stress Responses in Biology and Medicine  4th Cell Stress Society International (CSSI) Congress on Stress Responses in Biology and Medicine

     More details

    Event date: 2009.10

    Language:English  

    Venue:北海道  

    国際学会

  • Hideyuki J Majima, Hiroko P Indo, Kazuo Tomita, Yoichiro Iwashita, Hiromi Suzuki, Daisuke Masuda, Toru Shimazu, Akira Higashibata, Takashi Q Yamazaki, Sachiko Yano and Noriaki Ishioka   Gene Expression Changes of Human Neuron-like Cell Line, NB-1 exposed to Low-Dose X-irradiation.  

    日本宇宙生物科学会第23回大会  日本宇宙生物科学会第23回大会

     More details

    Event date: 2009.10

    Language:Japanese  

    Venue:茨城  

    国内学会

  • Hideyuki J Majima, Hiroko P Indo, Kazuo Tomita, Yoichiro Iwashita, Hiromi Suzuki, Daisuke Masuda, Toru Shimazu, Akira Higashibata, Noriaki Ishioka   Gene expression analysis by RT-PCR for human neuron-like cells exposed to cosmic rays   International conference

    17th IAA Humans in Space Symposium  17th IAA Humans in Space Symposium

     More details

    Event date: 2009.6

    Language:English  

    Venue:ロシア  

    国際学会

  • Hiroko P Indo, Kazuo Tomita, Sompong Sriburee, Hirofumi Matsui,Toshihiko Ozawa, Hideyuki J Majima   Antioxidative response in a rat gastric cells its transformed cell line RGK1  

    第8回日本ミトコンドリア学会年会  第8回日本ミトコンドリア学会年会

     More details

    Event date: 2008.12

    Language:Japanese  

    Venue:東京  

    国内学会

  • Hiroko P Indo, Kazuo Tomita, Shigeaki Suenaga, Tsuyoshi Sato, Hsiu-Chuan Yen, Toshihiko Ozawa, Hideyuki J Majima   Mitochondrial Signal Lacking Manganese Superoxide Dismutase Failed to Prevent Apoptosis by X-irradiation in a Human Hepatocellular Carcinoma Cell Line, HLE   International conference

    The 7th Asian Congress of Oral and Maxillofacial Radiology (ACOMFR 2008)  The 7th Asian Congress of Oral and Maxillofacial Radiology (ACOMFR 2008)

     More details

    Event date: 2008.11

    Language:English  

    Venue:Nara, Japan  

    国際学会

  • 犬童寛子、富田和男、松井裕史、小澤俊彦、馬嶋秀行   ミトコンドリア由来活性酸素がNrf2-keap1系を調節する  

    第8回日本抗加齢医学会総会  第8回日本抗加齢医学会総会

     More details

    Event date: 2008.6

    Language:Japanese  

    Venue:東京  

    国内学会

  • 犬童寛子   MnSODが放射線抵抗性をひきおこす  

    医学放射線学会生物部会第46回大会  医学放射線学会生物部会第46回大会

     More details

    Event date: 2007.7

    Language:Japanese  

    Venue:茨城  

    国内学会

  • INDO Hiroko P.,TOMITA Kazuo,Yen HC,Ozawa T,MAJIMA Hideyuki J.   No functional role of mitochondrial signal lacking manganese superoxide dismutase in prevention of apoptosis by X-irradiation in a human hepatocellular carcinoma cell line, HLE.   International conference

    The 4th Annual Scientific Meeting of the Asian Society for Mitochondrial Research and Medicine (ASMRM)  The 4th Annual Scientific Meeting of the Asian Society for Mitochondrial Research and Medicine (ASMRM)

     More details

    Event date: 2007.2

    Language:English  

    Venue:韓国  

    国際学会

  • 犬童寛子、富田和男、末永重明、下小野田一騎、竹之内剛、井尻幸成、Hsiu-Chuan Yen、松山隆美、小宮節郎、小澤俊彦、馬嶋秀行   143BとRho0細胞においてHumaninタンパクは放射線誘導ミトコンドリア由来活性酸素、脂質過酸化、アポトーシスを抑制する  

    第6回日本ミトコンドリア学会年会  第6回日本ミトコンドリア学会年会

     More details

    Event date: 2006.12

    Language:Japanese  

    Venue:神奈川  

    国内学会

  • 犬童寛子,富田和男,小澤俊彦,馬嶋秀行   ミトコンドリアDNA障害及び電子伝達系阻害によりミトコンドリア内活性酸素発生が増大する  

    第27回日本フリーラジカル学会学術集会  第27回日本フリーラジカル学会学術集会

     More details

    Event date: 2005.6

    Language:Japanese  

    Venue:岡山  

    国内学会

  • INDO Hiroko P.,TOMITA Kazuo,Hsiu-Chuan Yen,Ozawa T, MAJIMA Hideyuki J.   Mitochondrial Signal Lacking Manganese Superoxide Dismutase Failed to Prevent Cell Death by X-irradiation in a Human Hepatocellular Carcinoma Cell Line, HLE   International conference

    SFRBM'S 11th Annual Meeting  SFRBM'S 11th Annual Meeting

     More details

    Event date: 2004.11

    Language:English  

    Venue:アメリカ合衆国  

    国際学会

  • 犬童寛子,富田和男,末永重明,佐藤強志,岡田淳徳,馬嶋秀行   X線照射によるアポト??シスには照射後にミトコンドリアから生ずる活性酸素が重要な役割を果たす、Reactive Oxygen Species(ROS) Generated from Mitochondria Play Important Roles in Xray-irradiated Apoptosis  

    第45回日本歯科放射線学会総会  第45回日本歯科放射線学会総会

     More details

    Event date: 2004.9

    Language:Japanese  

    Venue:広島  

    国内学会

  • 犬童寛子,富田和男,岩下洋一朗,浦野泰照,長野哲雄,小澤俊彦,馬嶋秀行   ミトコンドリア移行シグナル欠損MnSODは放射線誘導細胞死を抑制しない  

    第26回日本フリーラジカル学会学術集会  第26回日本フリーラジカル学会学術集会

     More details

    Event date: 2004.6

    Language:Japanese  

    Venue:山形  

    国内学会

  • 犬童寛子,富田和男,小澤俊彦,長野哲雄,馬嶋秀行:   MnSODが放射線抵抗性を引き起こす  

    第8回がん分子標的治療研究会総会  第8回がん分子標的治療研究会総会

     More details

    Event date: 2004.5

    Language:Japanese  

    Venue:鹿児島  

    国内学会

  • 犬童 寛子   デンタル、パノラマそしてコーンビームCTから診えるもの 読影のポイントと注意点  

    特定非営利活動法人日本歯科保存学会学術大会プログラムおよび講演抄録集  2021.5  (NPO)日本歯科保存学会

     More details

    Language:Japanese  

  • 松本 邦史, 犬童 寛子, 福井 怜, 出澤 幸, 雨海 俊彦, 澤田 久仁彦, 江島 堅一郎, 浅野 正岳, 新井 嘉則, 本田 和也   Sclerosing Odontogenic Carcinomaの2例  

    歯科放射線  2021.5  (NPO)日本歯科放射線学会

     More details

    Language:Japanese  

▼display all