Updated on 2025/06/18

写真a

 
YOKOGAWA Yukiko
 
Organization
Research Field in Science, Science and Engineering Area Graduate School of Science and Engineering (Science) Department of Science Chemistry Program Lecturer
Title
Lecturer

Degree

  • Doctor (Science) ( 1993.4   Kobe University )

Research Interests

  • Organic Synthesis

  • nylon analogue

  • Organic Synthesis

  • luciferin derivative

Research Areas

  • Nanotechnology/Materials / Synthetic organic chemistry

  • Environmental Science/Agriculture Science / Environmental materials and recycle technology

  • Nanotechnology/Materials / Synthetic organic chemistry

  • Environmental Science/Agriculture Science / Environmental load reduction and remediation

Education

  • Kobe University

    1989.4 - 1991.8

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    Country： Japan

  • Kobe University   Graduate School, Division of National Science and Technology

    - 1991

  • Kobe University

    - 1991

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    Country： Japan

  • Kobe University   Faculty of Science

    - 1987

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    Country： Japan

  • Kobe University   Faculty of Science

    - 1987

Research History

  • Kagoshima University   Research Field in Science, Science and Engineering Area Graduate School of Science and Engineering (Science) Department of Science Chemistry Program   Lecturer

    2020.4

  • Kagoshima University

    1991.9

  • Kagoshima University   Research Field in Science, Science and Engineering Area Graduate School of Science and Engineering (Science) Chemistry and Bioscience Course   Lecturer

    1991.9 - 2020.3

Professional Memberships

  • 有機合成化学協会

    2015.10

  • 日本化学会

    2015.10

  • 有機合成化学協会

  • 日本化学会

  • The Society of Synthetic Chemistry, Japan

  • The Chemical Society of Japan

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Papers

  • Shiraishi Y., Kato D.I., Miyazaki K., Yonemura M., Furuno Y., Yokoyama R., Yokogawa Y., Nonaka S., Kaneko Y., Ebata K., Himeda Y., Negoro S. .  Quantitative nylon monomerization by the combination of chemical pretreatment and enzymatic hydrolysis using nylon hydrolases .  PLoS ONE20 ( 2 February ) e0318641   2025.2Reviewed International journal

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    Language：English   Publishing type：Research paper (scientific journal)   Publisher：PLoS ONE  

    Nylons, derived from fossil fuels, are widely used for their toughness and flexibility, but they pose environmental concerns due to their low biodegradability. This study explored an efficient method for the monomerization of polymeric nylons, specifically nylon-6 and nylon-6,6, through a combination of chemical pretreatment and enzymatic hydrolysis using two kinds of nylon hydrolases, NylB and NylC (Nyl series enzymes). To break down the strong intermolecular hydrogen bonding between polymer chains of nylon, two pretreatment methods were investigated: homogeneous dispersion and soluble oligomerization induced by acid treatment. Homogeneous dispersion enhances water solubility, while soluble oligomerization reduces the molecular weight. These pretreatments significantly increased the enzyme sensitivity of the nylons, resulting in nearly complete conversion into monomers by Nyl series. Finally the convincing monomerization toward market products such as used fishing nets was also achieved. This study highlights the potential of this methodology for chemical recycling, offering a promising solution for reducing environmental impacts and achieving a circular economy for nylon products.

    DOI： 10.1371/journal.pone.0318641

    Scopus

    PubMed

  • Rafia Usman, YukikoYokogawa, Aki Mihata, and Junichi Kurawaki .  Facile Synthesis of Silver Nanoparticles Using a Novel Benzenethiol Derivative: Addition Effect of Cationic Surfactants .  e-Journal of Surface Science of Nanotechnology13   440 - 444   2015Reviewed

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    Language：English   Publishing type：Research paper (scientific journal)  

  • Tetsuo Iwagawa, Kanta Hashimoto, Yukiko Yokogawa, Hiroaki Okamura, Munehiro Nakatani, Matsumi Doe, Yoshiki Morimoto and Kaoru Takemura .  Cytotoxic Biscembranes from the Soft Coral Sarcophyton glaucum .  Journal of Natural Products・American Chemical Society72 ( 5 ) 946 - 949   2009.3Reviewed

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    Language：English   Publishing type：Research paper (scientific journal)  

  • Tetsuo Iwagawa, Miho Miyazaki, Yukiko Yokogawa, Hiroaki Okamura, Munehiro Nakatani, Matsumi Doe, Yoshiki Morimoto, and Kaoru Takemura .  Aplysinopsin Dimers from a Stony Coral. Tubastraea aurea .  Heterocycles75 ( 8 ) 2023 - 2028   2008.8Reviewed

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    Language：English   Publishing type：Research paper (scientific journal)  

  • Toshio Itahara and Yukiko Yokogawa .  Self-Organization of Adenine and Thymine Derivative in Thermotropic Liquid Crystal .  Journal of Molecular Structure827 ( 2 ) 95 - 100   2007.2Reviewed

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    Language：English   Publishing type：Research paper (scientific journal)  

  • Mitsuteru Higashimura, Keita Imamura, Yukiko Yokogawa, and Tsutomu Sakakibara .  Novel Dimerization,Alkoxylation and Sulfidation of Olefins Catalyzed by RuCl3・nH2O .  Chemistry Letters33 ( 6 ) 728 - 729   2004.6Reviewed

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    Language：Japanese   Publishing type：Research paper (scientific journal)  

  • Yukiko Itojima, Yoko Ogawa, Katsushige Tsuno, Nobuo Handa and Hiroshi Yanagawa .  Spontaneous Formation of Helical Structures from Phospholipid-Nucleoside Conjugates .  Biochemistry31   4757 - 4765   1992Reviewed

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    Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

  • Yukiko Itojima, Nobuo Handa, Katsushige Tsuno and Hiroshi Yanagawa .  Formation and morphology of helical structures from phospholipid-ribonucleoside conjugates in an acidic solution .  Nucleic Acids Research Symposium Series ( 25 ) 43 - 44   1991

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    Authorship：Lead author   Language：English   Publishing type：Research paper (conference, symposium, etc.)  

  • Yukiko Itojima and Keisuke Ito .  Prebiotic Synthesis of Organic Compounds by Electric Discharge in Simulated Interstellar Space .  Memoirs of the Graduate School of Science and Technology, Kobe University,8-A   1 - 18   1990Reviewed

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    Authorship：Lead author   Language：English   Publishing type：Research paper (bulletin of university, research institution)  

  • Yukiko Itojima, Yoko Ogawa, Katsushige Tsuno and Hiroshi Yanagawa .  Helical structures of nucleic acid-lipid conjugates: formation and morphology of helical structures from dimyristoyl-5’-phosphatidylribonucleosides .  Nucleic Acids Research Symposium Series ( 22 ) 123 - 124   1990Reviewed

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    Authorship：Lead author   Language：English   Publishing type：Research paper (conference, symposium, etc.)  

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Books

  • 焼酎粕と生ゴミの堆肥化 －ミミズによる分解－

    横川由起子（ Role： Sole author）

    環境報告書・鹿児島大学  2010.9 

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    Language：Japanese Book type：Report

  • 鹿児島大学生協の生ゴミの処理の現状と対策

    横川由起子、榊原邁（ Role： Joint author）

    鹿児島大学エコキャンパスプロジェクト活動成果報告書・鹿児島大学  2007.3 

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    Language：Japanese Book type：Report

  • 焼酎製造廃液およびかつお節製造廃液の液体肥料化

    榊原邁、横川由起子（ Role： Joint author）

    鹿児島大学エコキャンパスプロジェクト報告書・鹿児島大学  2006.3 

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    Language：Japanese Book type：Report

  • 郡元キャンパスにおけるゴミ処理場跡のダイオキシン調査

    榊原邁、横川由起子（ Role： Joint author）

    鹿児島大学エコキャンパスプロジェクト成果報告書・鹿児島大学  2005.3 

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    Language：Japanese Book type：Report

Presentations

  • 横山理沙, 古野洋子, 米村まいな, 山田美和, 横川由起子, 加藤太一郎   11-アミノウンデカン酸を資化する海洋性細菌Pseudophaeobacter sp. E1株からのPHA産生能力の発見  

    第24回生体触媒化学シンポジウムin岐阜 

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    Event date： 2024.10 - 2024.11

    Language：Japanese   Presentation type：Poster presentation  

    Venue：みんなの森　ぎふメディアコスモス   Country：Japan  

  • 米村まいな, 加藤太一郎, 横山理沙, 横川由起子, 谷池俊明, Yingjun An,高原淳, 小島正幸, 嶋中博之, 金子達雄, 根来誠司   分子内にピロリドン環を有するポリアミドiNylonの光分解  

    日本化学会第105春季年会  日本化学会

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    Event date： 2025.3

    Language：Japanese   Presentation type：Poster presentation  

    Venue：関西大学千里山キャンパス   Country：Japan  

  • 白石雄樹, 加藤太一郎, 横山理沙, 古野洋子, 横川由起子, 根来誠司   化学-酵素的加水分解による汎用ナイロンの定量的なモノマー化技術  

    日本化学会第105春季年会  日本化学会

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    Event date： 2025.3

    Language：Japanese   Presentation type：Poster presentation  

    Venue：関西大学千里山キャンパス   Country：Japan  

  • 千葉殖幹, 緒方美咲，吉崎由美子，乾幹夫，高峰和則，上園保仁，横川由起子，高橋隆二   黒糖・芋焼酎由来成分のグレリン様摂食促進作用の生体での検証  

    日本農芸化学会　2024年度大会  2024.3  日本農芸化学会

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    Event date： 2024.3

    Language：Japanese   Presentation type：Oral presentation (general)  

    Venue：東京農業大学   Country：Japan  

  • Masanori Kasai, Shoko Hososhima, Asami Tanaka, Kaori Fukumoto, Hirotoshi Kawano, Ryotarou Okayama, Rio Hara, Keiji Warashina, Yukiko Yokogawa   D-menthol increases and decreases the respiratory frequency via TRPA1 receptors and GABAA receptors in goldfish, respectively.   Invited

    The 40h Annual Meeting of the Japan Neuroscience Society (Chiba) 

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    Event date： 2017.7

    Language：English   Presentation type：Poster presentation  

  • Shoko Hososhima, Asami Tanaka, Kaori Fukumoto, Hirotoshi Kawano, Ryotarou Okayama, Yukiko Yokogawa Masanori Kasai   Involvement of TRPA1 receptors and GABAA receptors in the effects of menthol on goldfish   International conference

    International Congress on Chemical, Biological and Environmental Sciences 

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    Event date： 2017.5

    Language：English   Presentation type：Poster presentation  

    Venue：Kyoto  

  • Anesthetic effect of menthol via GABAA-receptors on goldfish  

    The 39th Annual Meeting of the Japan Neuroscience Society 

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    Event date： 2016.7

    Language：Japanese   Presentation type：Poster presentation  

  • Masanori Kasai, Shoko Hososhima, Asami Tanaka, Kaori Fukumoto, Hirotoshi Kawano, Ryotarou Okayama, Rio Hara, Keiji Warashina, Yukiko Yokogawa   D-menthol increases and decreases the respiratory frequency via TRPA1 receptors and GABAA receptors in goldfish, respectively   Invited

    The 40h Annual Meeting of the Japan Neuroscience Society (Chiba) 

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    Event date： 2016.7

    Language：Japanese   Presentation type：Poster presentation  

  • MASANORI KASAI, Moe Watanabe, Chihiro Matsunaga, Kurumi Mineno, Ryota Karakama, Tsubasa Matsumoto, Yukiko Yokogawa, Takanori Ikenaga   Anesthetic and anti-anxiety effects of menthol on rodent  

    The 38th Annual Meeting of the Japan Neuroscience Society 

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    Event date： 2015.7

    Language：Japanese   Presentation type：Poster presentation  

    Venue：Kobe  

    The odor of menthol is believed to be an important aspect of its effectiveness in treating various illnesses, and when administered intraperitoneally (IP), it has shown antianxiety effects in mice. We have reported that menthol can also play a role in the induction of anesthesia in fishes. However, it has not been elucidated whether menthol produces anesthesia in rodent.
    To examine whether mice demonstrate an anesthetic response to menthol, the effect of IP-injected menthol in male ICR mice was tested. The menthol was administered to three groups of mice in doses of 0.25, 0.5, and 0.75 g/kg body weight (BW) and it induced an anesthetic response in 40, 60, and 100% of mice, respectively. Menthol was also administered to three groups of mice in doses of 0.5, 0.75, and 1.0 g/kg BW and it induced a surgical anesthetic response in 20, 60, and 80% of mice, respectively.
    The effects of orally administering menthol were examined by adding it to drinking water. Drinking water with menthol (menthol solution, 0.005 - 1.0 mM) did not induce the anesthetic effect on the mice and Wistar rats. In the rats, menthol solutions of 0.005 and 0.03 mM significantly increased running wheel activities, food intake, and amount of drinking, and the 0.03 mM solution decreased BW. The 0.01 mM solution significantly increased locomotor activities and time spent in the light box in an unfamiliar environment during the dark/light box test and time in the center during an open field test. In mice, the 0.1 mM solution increased activities in the center zone during an open field test. In rats with adjuvant arthritis (AA), the 0.03 mM menthol solution significantly attenuated a decrease of running wheel activity during an acute phase (from 0 to 3 days following inoculation).
    The present results demonstrate that menthol has an anesthetic effect on rodents as well as fish, and oral administration may reduce anxiety and induce analgesic effects in rodents, suggesting that menthol is an anxiolytic and analgesic.

  • 前田環，横川由起子，神長暁子   入試方法の多様化と理科教育  

    日本化学会西日本大会  日本化学会西日本大会

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    Event date： 2010.11

    Language：Japanese  

    Venue：熊本大学  

    国内学会

  • 西川真司、横川由起子、榊原邁   RuCl3・H2Oによるオレフィンの位置選択的二量化・三量化  

    化学関連支部合同九州大会  化学関連支部合同九州大会

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    Event date： 2007.7

    Language：Japanese  

    Venue：福岡  

    国内学会

  • 村山聡、横川由起子、榊原邁   Pd(Ⅱ）／ジアルキルアニリン系の一電子移動反応におけるラジカルカチオンの挙動  

    化学関連支部合同九州大会  化学関連支部合同九州大会

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    Event date： 2004.7

    Language：Japanese  

    Venue：福岡  

    国内学会

  • 横川由起子、天本由加里、榊原邁   ルテニウム触媒によるアルケンとアルキンの新規二量化、三量化  

    化学関連支部合同九州大会  化学関連支部合同九州大会

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    Event date： 2004.7

    Language：Japanese  

    Venue：福岡  

    国内学会

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Works

  • 財団法人 実吉奨学会

    1995

  • 財団法人 鹿児島県育英財団

    1995

Research Projects

  • Reuse of Wastewater from Making Schochu and Katsuobushi : Application as a Liquid Fertilizer

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    Authorship：Principal investigator  Grant type：Competitive