Updated on 2024/10/11

写真a

 
YAMATO Osamu
 
Organization
Research Field in Veterinary Medicine, Agriculture, Fisheries and Veterinary Medicine Area Joint faculty of Veterinary Medicine Joint Department of Veterinary Medicine Professor
Title
Professor

Degree

  • PhD ( 1994.3   Hokkaido University )

Research Interests

  • ニンニク

  • タマネギ

  • 機能性

  • ネギ属植物

  • ライソゾーム蓄積病

  • 動物モデル

  • 動物遺伝子病

Research Areas

  • Others / Others  / 獣医臨床遺伝学

  • Others / Others  / 獣医臨床生化学

  • Others / Others  / 獣医臨床病理学

Research History

  • Kagoshima University   Professor

    2012.4

  • Kagoshima University

    2006.4

Professional Memberships

  • 日本犬保存会

    2015.10

  • 獣医臨床遺伝研究会

    2015.10

  • 日本ライソゾーム病研究会

    2015.10

  • 獣医神経病学会

    2015.10

  • 日本先天代謝異常学会

    2015.10

  • American Society of Veterinary Clinical Pathology (ASVCP)

    2015.10

  • International Society for Animal Clinical Pathology (ISACP)

    2015.10

  • 日本獣医師会(日本小動物獣医学会・日本産業動物獣医学会)

    2015.10

  • 日本獣医学会

    2015.10

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Papers

  • Widodo OS, Uno S, Kokushi E, Yamato O, Mardianto MFF, Shinya U, Kano Y, Kawashima C, Fushimi Y, Ono T, Taniguchi M, Takagi M* .  Exposure of cattle breeding herds to naturally co-contaminated zearalenone and eeoxynivalenol: The relevance of a urinary mycotoxin monitoring system for herd health and food safety .  Toxins16 ( 9 ) 402   2024.9Exposure of cattle breeding herds to naturally co-contaminated zearalenone and eeoxynivalenol: The relevance of a urinary mycotoxin monitoring system for herd health and food safetyReviewed

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  • Hashimoto S, Hasan MN*, Arif M, Nozaki N, Husna AA, Furusawa Y, Sogawa T, Takahashi K, Kuramoto T, Noguchi A, Takahashi M, Yamato O, Rahman MM, Miura N* .  Aberrantly expressed tRNA-Val fragments can distinguish canine hepatocellular carcinoma from canine hepatocellular adenoma .  Genes15 ( 8 ) 1024   2024.8Aberrantly expressed tRNA-Val fragments can distinguish canine hepatocellular carcinoma from canine hepatocellular adenomaReviewed

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  • Priyo TW Jr, Edo A, Taura Y, Yamato O, Ono T, Taniguchi M, Widodo OS, Islam MS, Maki S, Takagi M .  A novel approach for evaluating pregnancy-associated glycoprotein and inflammation markers during the postpartum period in Holstein Friesian cows .  Animals14 ( 10 ) 1459   2024.5Reviewed International journal

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:MDPI  

    Simple Summary

    Pregnancy-associated glycoproteins (PAG) secreted from fetoplacental binucleate cells are used in clinical practice for the early detection of bovine pregnancy. This study examined the postpartum PAG concentration to monitor binucleated cell clearance during postpartum uterine repair. PAG concentration was correlated with inflammatory parameters (serum amyloid A and milk amyloid A), postpartum inflammatory conditions (mastitis, ketosis, and follicular cysts), and FOXP3 gene-related repeat breeders. Excessive inflammation occurring during the postpartum period may reduce PAG concentration gradually. Clarifying the mechanism of decreased PAG concentration during the postpartum period has a beneficial effect on improving reproductive efficiency, performance, and reproduction aspects.
    Abstract

    We evaluated the relationship between decreased pregnancy-associated glycoprotein (PAG) levels, inflammatory parameters (serum amyloid A [SAA] and milk amyloid A [MAA]), postpartum inflammatory conditions (mastitis, ketosis, and follicular cysts), and the FOXP3 gene. Nineteen Holstein-Friesian cows were included in this study. Up to approximately eight weeks after delivery, weekly health examinations were performed for mastitis and ketosis, and reproductive organ ultrasonography was performed. The decreasing PAG rate was negatively correlated with SAA concentration (r = −0.493, p = 0.032). Cows with mastitis exhibited a slower trend of PAG decrease (p = 0.095), and a greater percentage of these cows had MAA concentrations above 12 µg/mL (p = 0.074) compared with those without mastitis. A negative correlation, although nonsignificant (r = −0.263, p = 0.385), was observed between the day-open period and decreased PAG rate. The day-open period was correlated with the presence or absence of follicular cysts (p = 0.046). Four cows that developed follicular cysts were homozygous for the G allele of the FOXP3 gene related to repeat breeders. These results indicate a relationship between a decreased PAG rate and inflammatory status during the postpartum period. Thus, suppressing inflammation during the perinatal period may improve reproductive efficiency in the dairy industry.
    Keywords: Holstein Friesian; FOXP3 gene; pregnancy-associated glycoprotein; serum amyloid A; milk amyloid A

    DOI: 10.3390/ani14101459

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  • Yabuki A*, Ando T, Tanabe M, Kurahara N, Yamato O .  Severe glomerular fibrin thrombosis in a dog .  J Vet Med Sci86 ( 1 ) 87 - 91   2024.1Severe glomerular fibrin thrombosis in a dogReviewed

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  • Tsuka T*, Sunden Y, Morita T, Islam MS, Yamato O .  Ultrasonography and postmortem magnetic resonance imaging of bilateral ocular disease in a heifer .  Ruminants4 ( 1 ) 125 - 135   2024.1Ultrasonography and postmortem magnetic resonance imaging of bilateral ocular disease in a heiferReviewed

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  • Uno Y*, Yamato O, Yamazaki H* .  Transcript abundance of hepatic drug-metabolizing enzymes in two dog breeds compared with 14 species including humans .  Drug Metab Pharmacokinet55   101002   2024.1Transcript abundance of hepatic drug-metabolizing enzymes in two dog breeds compared with 14 species including humansReviewed

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  • Hasan MN, Rahman MM, Husna AA, Nozaki N, Yamato O, Miura N* .  YRNA and tRNA fragments can differentiate benign from malignant canine mammary gland tumors .  Biochem Biophys Res Commun691   149336   2024.1YRNA and tRNA fragments can differentiate benign from malignant canine mammary gland tumorsReviewed

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  • Sasazaki N, Toda K, Hasunuma H, Matsumoto D, Shinya U, Yamato O, Obi T, Higaki T, Widodo OS, Ishii K, Igari N, Kazami D, Taniguchi M, Takagi M* .  Effects of dietary feed supplementation with heat-treated Lactobacillus sakei HS-1 on the health status, blood parameters, and fecal microbes of Japanese Black calves before weaning .  Vet World16 ( 11 ) 2293 - 2302   2023.11Effects of dietary feed supplementation with heat-treated Lactobacillus sakei HS-1 on the health status, blood parameters, and fecal microbes of Japanese Black calves before weaningReviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.14202/vetworld.2023.2293-2302

  • Kurahara N, Yutsudo A, Furusawa Y, Yamato O, Miyoshi N, Hifumi T, Yabuki A .  Immunohistochemical analysis of renal oxidative damage in senior and geriatric cat with chronic kidney disease .  J Comp Pathol207   14 - 17   2023.11Immunohistochemical analysis of renal oxidative damage in senior and geriatric cat with chronic kidney diseaseReviewed

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  • 10. Takahashi K, Nango H, Ushijima M, Takashima M, Nakamoto M, Matsutomo T, Jikihara H, Arakawa N, Maki S, Yabuki A, Endo Y, Yamato O* .  Therapeutic effect of aged garlic extract on gingivitis in dogs .  Front Vet Sci10   1277272   2023.11Therapeutic effect of aged garlic extract on gingivitis in dogsReviewed

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  • Ijiri M, Akioka K, Kitano T, Miura H, Ono HK, Terashima R, Fujimoto Y, Matsuo T, Yamato O, Kawaguchi H* .  Acupuncture treatment improves transport stress in microminipigs through the acupoint in ears .  In Vivo37 ( 5 ) 2100 - 2104   2023.9Acupuncture treatment improves transport stress in microminipigs through the acupoint in earsReviewed

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    DOI: 10.21873/invivo.13307

  • Ueno H*, Itoh T, Nasuno T, Konno W, Kondo A, Konish I, Inukai H, Kokubo D, Isaka M, Islam MS, Yamato O .  Pyruvate kinase deficiency mutant gene carriage in stray cats and rescued cats from animal hoarding in Hokkaido, Japan .  J Vet Med Sci85 ( 5 ) 972 - 976   2023.9Pyruvate kinase deficiency mutant gene carriage in stray cats and rescued cats from animal hoarding in Hokkaido, JapanReviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1292/jvms.23-0091

  • Shinya U, Yamato O, Iwamura Y, Kato T, Hamada Y, Widodo OS, Taniguchi M, Takagi M* .  Usefulness of measuring serum amyloid A concentration in Japanese Black cattle in clinical practice .  Vet Sci10 ( 8 ) 528   2023.8Usefulness of measuring serum amyloid A concentration in Japanese Black cattle in clinical practiceReviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3390/vetsci10080528

  • Priyo TW Jr, Uno S, Kokushi E, Toda K, Hasunuma H, Matsumoto D, Yamato O, Ohtani M, Widodo OS, Pambudi D, Taniguchi M, Takagi M* .  Measurement of serum short-chain fatty acid concentrations in cattle after oral administration of difructose anhydride III .  Vet World16 ( 7 ) 1505 - 1511   2023.7Measurement of serum short-chain fatty acid concentrations in cattle after oral administration of difructose anhydride III

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  • Rakib TM, Islam MS, Uddin MM, Rahman MM, Yabuki A, Yamagami T, Morozumi M, Uchida K, Maki S, Faruq AA, Yamato O* .  Novel mutation in the feline NPC2 gene in cats with Niemann-Pick disease .  Animals13 ( 11 ) 1744   2023.5Novel mutation in the feline NPC2 gene in cats with Niemann-Pick disease

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  • Widodo OS, Pambudi D, Etoh M, Kokushi E, Uno S, Yamato O, Taniguchi M, Lamid M, Takagi M* .  Practical application of urinary zearalenone monitoring system for feed hygiene management of a Japanese Black cattle breeding herd—relevance to anti-Müllerian hormone and serum amyloid A clarified from two years survey .  Toxins15 ( 5 ) - 317   2023.4Practical application of urinary zearalenone monitoring system for feed hygiene management of a Japanese Black cattle breeding herd—relevance to anti-Müllerian hormone and serum amyloid A clarified from two years surveyReviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3390/toxins15050317

  • Rakib TM, Islam MS, Tanaka S, Yabuki A, Pervin S, Maki S, Faruq AA, Tacharina MR, Yamato O* .  Novel mutation in the feline GAA gene in a cat with glycogen storage disease type II (Pompe disease) .  Animals13 ( 8 ) 1336   2023.4Novel mutation in the feline GAA gene in a cat with glycogen storage disease type II (Pompe disease)

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3390/ani13081336

  • Furusawa Y, Shima-Sawa M, Hifumi T, Miyoshi N, Yamato O, Yabuki A* .  Usefulness and limitations of cryopreservation for immunocytochemical staining of canine cytological specimens for detection of cytokeratin and vimentin .  Vet Sci10 ( 2 ) 153   2023.2Usefulness and limitations of cryopreservation for immunocytochemical staining of canine cytological specimens for detection of cytokeratin and vimentinReviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3390/vetsci2103596

  • Noguchi A, Kurahara N, Yamato O, Ichii O, Yabuki A* .  Lectin histochemistry of the normal feline kidney .  Vet Sci10 ( 1 ) 26   2023.1Lectin histochemistry of the normal feline kidneyReviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3390/vetsci2019086

  • 原田幸治, 大和修, 佐々木直樹* .  肺・肝臓および頚部に病変が認められた重種馬におけるラテックス比濁免疫測定法を用いた血清アミロイドA(SAA)値の検討について .  2023年度馬に関する症例等業績論文集   13 - 17   2023肺・肝臓および頚部に病変が認められた重種馬におけるラテックス比濁免疫測定法を用いた血清アミロイドA(SAA)値の検討についてReviewed

  • Uno Y, Murayama N, Ijiri M, Kawaguchi H, Yamato O, Shiraishi M, Asano A, Teraoka H, Mizukawa H, Nakayama SMM, Ikenaka Y, Ishizuka M, Yamazaki H* .  Cytochrome P450 2J (CYP2J) genes in dogs, cats, and pigs are expressed and encode functional drug-metabolizing enzymes .  Drug Metab Dispos50 ( 11 ) 1434 - 1441   2022.11Cytochrome P450 2J (CYP2J) genes in dogs, cats, and pigs are expressed and encode functional drug-metabolizing enzymesReviewed

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  • Uno Y*, Shimizu M, Ogawa Y, Makiguchi M, Kawaguchi H, Yamato O, Ishizuka M, Yamazaki H .  Molecular and functional characterization of flavin-containing monooxygenases in pigs, dogs, and cats .  Biochem Pharmacol202 - 115125   2022.8Molecular and functional characterization of flavin-containing monooxygenases in pigs, dogs, and catsReviewed

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  • Chen HW, Lai YC, Rahman MM, Husna AA, Hasan MN, Hatai H, Miyoshi N, Yamato O, Miura N* .  NGS-identified miRNAs in canine mammary gland tumors show unexpected expression alterations in qPCR analysis .  In Vivo36 ( 4 ) 1628 - 1636   2022.7NGS-identified miRNAs in canine mammary gland tumors show unexpected expression alterations in qPCR analysisReviewed

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  • Widodo OS, Nishihara S, Pambudi D, Kusakabe KT, Taura Y, Nishi Y, Yamato O, Taniguchi M, Takagi M* .  Relationship between ovary size and anti-Müllerian hormone levels in Holstein–Friesian cows .  Front Vet Sci9   828123   2022.6Relationship between ovary size and anti-Müllerian hormone levels in Holstein–Friesian cowsReviewed

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  • Nueangphuet P, Hamano T, Hirai T*, Sakaguchi Y, Sonoda H, Otsuka M, Yamato O, Hobo S, Ikeda M, Yamaguchi R .  Rhabdomyolysis, myoglobinuric nephrosis, and crystalline nephropathy in a bottlenose dolphin .  J Vet Diagn Invest34 ( 4 ) 668 - 673   2022.6Rhabdomyolysis, myoglobinuric nephrosis, and crystalline nephropathy in a bottlenose dolphinReviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1177/10406387221090516

  • Ijiri M, Odo K, Sato M, Kawaguchi M, Fujimoto Y, Miura N, Matsuo T, Hou DX, Yamato O, Tanabe T, Kawaguchi H* .  Potential biomarkers for chronic seasonal heat stress in Kagoshima Berkshire pigs reared in the subtropical region .  J Vet Res66 ( 2 ) 209 - 214   2022.6Potential biomarkers for chronic seasonal heat stress in Kagoshima Berkshire pigs reared in the subtropical regionReviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.2478/jvetres-2022-0024

  • Maki S, Islam MS, TItoh T, Nurimoto M, Yabuki A, Furusawa Y, Kamishina H, Kobatake Y, Rakib TM, Tacharina MR, Yamato O* .  Molecular epidemiological survey for degenerative myelopathy in German Shepherd Dogs in Japan: allele frequency and clinical progression rate .  Animals12 ( 13 ) 1647   2022.6Molecular epidemiological survey for degenerative myelopathy in German Shepherd Dogs in Japan: allele frequency and clinical progression rateReviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3390/ani12131647

  • Pervin S, Islam MS, Yorisada Y, Sakai A, Masamune S, Yabuki A, Rakib TM, Maki S, Tacharina MR, Yamato O* .  Carrier rate and mutant allele frequency of GM1 gangliosidosis in miniature Shiba Inus (Mame Shiba): population screening of breeding dogs in Japan .  Animals12 ( 10 ) 1242   2022.5Carrier rate and mutant allele frequency of GM1 gangliosidosis in miniature Shiba Inus (Mame Shiba): population screening of breeding dogs in JapanReviewed

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  • Pervin S, Islam MS, Tada N, Tsutsui T, Rahman MM, Yabuki A, Tacharina MR, Rakib TM, Maki S, Yamato O* .  Screening and carrier rate of neuronal ceroid lipofuscinosis in Chihuahua dogs in Japan .  Animals12 ( 9 ) 1210   2022.5Screening and carrier rate of neuronal ceroid lipofuscinosis in Chihuahua dogs in Japan

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  • Kimura S, Kamishina H, Hirata Y, Furuta K, Furukawa Y, Yamato O, Maeda S, Kamatari YO* .  Novel oxindole compounds inhibit the aggregation of amyloidogenic proteins associated with neurodegenerative diseases .  Biochim Biophys Acta1866 ( 5 ) 130114   2022.5Novel oxindole compounds inhibit the aggregation of amyloidogenic proteins associated with neurodegenerative diseasesReviewed

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  • Islam MS, Takagi M, Lee KW, Chang HS, Okawa H, Yunus M, Lestari TD, Tacharina MR, Pervin S, Rakib TM, Yabuki A, Yamato O* .  Frequency of an X-linked maternal variant of the bovine FOXP3 gene associated with infertility in different cattle breeds: a pilot study .  Animals12 ( 8 ) 1044   2022.4Frequency of an X-linked maternal variant of the bovine FOXP3 gene associated with infertility in different cattle breeds: a pilot studyReviewed

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  • Shinya U, Iwamura Y, Yamato O, Pambudi D, Widodo OS, Taniguchi M, Takagi M* .  Serum amyloid A concentration of healthy and clinically diseased Japanese Black breeding cattle – preliminary measurements for determining the cut-off concentrations .  Vet Sci9 ( 5 ) 198   2022.4Serum amyloid A concentration of healthy and clinically diseased Japanese Black breeding cattle – preliminary measurements for determining the cut-off concentrations

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  • Uehara Y, Furusawa Y, Islam MS, Yamato O, Hatai H, Ichii O, Yabuki A* .  Immunohistochemical expression of TGF-β1 in kidneys of cats with chronic kidney disease .  Vet Sci9 ( 3 ) 114   2022.3Immunohistochemical expression of TGF-β1 in kidneys of cats with chronic kidney diseaseReviewed

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  • Widodo OS, Etoh M, Kokushi E, Uno S, Yamato O, Pambudi D, Okawa H, Taniguchi M, Lamid M, Takagi M* .  Practical application of urinary zearalenone monitoring system for feed hygiene management of a Japanese Black cattle breeding herd .  Toxins14 ( 2 ) 143   2022.2Practical application of urinary zearalenone monitoring system for feed hygiene management of a Japanese Black cattle breeding herdReviewed

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  • Yu Y, Hasegawa D*, Hamamoto Y, Mizoguchi S, Fujimori T, Kubo Y, Islam MS, Yamato O .  Skeletal radiographic manifestation of GM2-gangliosidosis variant 0 (Sandhoff disease) in two Japanese domestic cats .  JFMS Open Rep8 ( 1 ) 2055116922   2022.2Skeletal radiographic manifestation of GM2-gangliosidosis variant 0 (Sandhoff disease) in two Japanese domestic catsReviewed

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  • Naito E, Nakata K, Sakai H, Yamato O, Islam MS, Maeda S, Kamishina H* .  Diffusion tensor imaging-based quantitative analysis of the spinal cord in Pembroke Welsh Corgis with degenerative myelopathy .  J Vet Med Sci83 ( 2 ) 199 - 207   2022.2Diffusion tensor imaging-based quantitative analysis of the spinal cord in Pembroke Welsh Corgis with degenerative myelopathyReviewed

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  • Tanaka S*, Suzuki R, Koyama H, Machida N, Yabuki A, Yamato O .  Glycogen storage disease in a young cat with heart failure .  J Vet Intern Med36 ( 1 ) 259 - 263   2022.1Glycogen storage disease in a young cat with heart failureReviewed

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  • Tamura S*, Tamura Y, Nakamoto Y, Hasegawa D, Tsuboi M, Uchida K, Yabuki A, Yamato O* .  Positioning head tilt in canine lysosomal storage disease: a retrospective observational descriptive study .  Front Vet Sci8   802668   2021.12Positioning head tilt in canine lysosomal storage disease: a retrospective observational descriptive studyReviewed

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  • Yoshimura N, Tsuka T*, Sunden Y, Morita T, Islam MS, Yamato O, Yoshimura T .  Ophthalmic findings in a septic calf with the concurrent exhibition of meningitis and endophthalmitis .  J Vet Med Sci83 ( 11 ) 1648 - 1652   2021.11Ophthalmic findings in a septic calf with the concurrent exhibition of meningitis and endophthalmitisReviewed

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  • Tamura S*, Tsuboi M, Ueoka N, Doi S, Tamura Y, Uchida K, Yabuki A, Yamato O* .  Adult-onset neuronal ceroid lipofuscinosis in a Shikoku Inu .  Vet Sci8 ( 10 ) 227   2021.10Adult-onset neuronal ceroid lipofuscinosis in a Shikoku Inu

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  • Kobatake Y*, Nakata K, HSakai H, Sasaki J, Yamato O, Takashima S, Nishii N, Maeda S, Islam MS, Kamishina H .  The long-term clinical course of canine degenerative myelopathy and therapeutic potential of curcumin .  Vet Sci8 ( 9 ) 192   2021.9The long-term clinical course of canine degenerative myelopathy and therapeutic potential of curcumin

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  • Kumagai M*, Kato S, Arakawa N, Otsuka M, Hamano T, Kashiwagi N, Yabuki A, Yamato O* .  Quantification of histidine-containing dipeptides in dolphin serum using a reversed-phase ion-pair high-performance liquid chromatography method .  Separations8 ( 8 ) 128   2021.8Quantification of histidine-containing dipeptides in dolphin serum using a reversed-phase ion-pair high-performance liquid chromatography method

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  • Tanaka N, Kimura S, Kamatari YO, Nakata K, Kobatake Y, Inden M, Yamato O, Urushitani M, Maeda S, Kamishina H* .  In vitro evidence of propagation of superoxide dismutase-1 protein aggregation in canine degenerative myelopathy .  Vet J274   105710   2021.8In vitro evidence of propagation of superoxide dismutase-1 protein aggregation in canine degenerative myelopathy

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  • Takaichi Y, Chambers JK*, Shiroma-Kohyama M, Haritani M, Une Y, Yamato O, Nakayama H, Uchida K. .  Feline spongy encephalopathy with a mutation in the ASPA gene. .  Vet Pathol   2021.7Feline spongy encephalopathy with a mutation in the ASPA gene.Reviewed

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  • Furusawa Y, Takahashi M, Shima-Sawa M, Hatai H, Miyoshi N, Yamato O, Yabuki A*. .  Immunocytochemical evaluation of epithelial-mesenchymal transition in epithelial tumors of dogs and cats. .  J Vet Med Sci   2021.7Immunocytochemical evaluation of epithelial-mesenchymal transition in epithelial tumors of dogs and cats.

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    DOI: 10.1292/jvms.21-0021

  • Naito E, Nakata K, Nakano Y, Nozue Y, Kimura S, Sakai H, Yamato O, Islam MS, Maeda S, Kamishina H. .  Changes of dorsal root ganglion volume in dogs with clinical signs of degenerative myelopathy detected by water-excitation magnetic resonance imaging. .  Animals12 ( 6 ) 1702   2021.6Changes of dorsal root ganglion volume in dogs with clinical signs of degenerative myelopathy detected by water-excitation magnetic resonance imaging.Reviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3390/ani11061702

  • Sasazaki N, Uno S, Kokushi E, Toda K, Shiiba A, Hasunuma H, Matsumoto D, Miyashita A, Yamato O, Okawa H, Ohtani M, Fink-Gremmels J, Taniguchi M, Takagi M*. .  Mitigation of sterigmatocystin exposure in cattle by difructose anhydride III feed supplementation and detection of urinary sterigmatocystin and serum amyloid A concentrations. .  Arch Anim Breed64 ( 1 ) 257 - 264   2021.6Mitigation of sterigmatocystin exposure in cattle by difructose anhydride III feed supplementation and detection of urinary sterigmatocystin and serum amyloid A concentrations.Reviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.5194/aab-64-257-2021

  • Matsumoto F, Shima-Sawa M, Furusawa Y, Yamato O, Yabuki A*. .  A rapid multiple immunofluorescence method of the simultaneous detection of CD20 and CD3 in canine and feline cytological samples. .  J Vet Med Sci83 ( 5 ) 832 - 836   2021.5Reviewed International journal

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:Japanese Society of Veterinary Science  

    <p>CD20 and CD3 are considered reliable markers for B and T cells, respectively. This study aimed to develop a rapid multiple immunofluorescence (RMIF) method for the detection of CD20 and CD3 on a single cytology slide. Air-dried smears were prepared using samples collected from dogs (n=26) and cats (n=6). Immunosignal detection using the newly developed method required 60 min. Clear immunosignals for CD20 and CD3 were detected in 24 of 26 samples in dogs and in all 6 cats. As the RMIF (CD20/CD3) method can detect markers of both B and T cells simultaneously on a single cytology smear, it would be an efficient tool for the immunophenotyping of canine and feline lymphoma samples.</p>

    DOI: 10.1292/jvms.20-0597

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  • Okawa H, Monniaux D, Mizokami C, Fujikura A, Takano T, Sato S, Shinya U, Kawashima C, Yamato O, Fushimi Y, Vos PLAM, Taniguchi M, Takagi M*. .  Association between anti-Müllerian hormone concentration and inflammatory factors in serum during the peripartum period in dairy cows. .  Animals11 ( 6 ) 1241   2021.5Association between anti-Müllerian hormone concentration and inflammatory factors in serum during the peripartum period in dairy cows.Reviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3390/ani11051241

  • Yabuki A*, Furusawa Y, Miyoshi N, Taniguchi K, Yamato O. .  Expression of neuronal nitric oxide synthase and renine in chronic kidney disease of young dogs caused by dysplastic kidneys. .  J Vet Med Sci83 ( 5 ) 837 - 840   2021.4Expression of neuronal nitric oxide synthase and renine in chronic kidney disease of young dogs caused by dysplastic kidneys.Reviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1292/jvms.21-0074

  • Hashimoto K, Kabatake Y, Asahina R, Yamato O, Islam MS, Sakai H, Nishida H, Maeda S, Kamishina H*. .  Up-regulated inflammatory signatures of the spinal cord in canine degenerative myelopathy. .  Res Vet Sci   2021.3Up-regulated inflammatory signatures of the spinal cord in canine degenerative myelopathy.Reviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.rvsc.2020.11.001

  • Up-regulated spinal microRNAs induce aggregation of superoxide dismutase 1 protein in canine degenerative myelopathy. .  Res Vet Sci   2021.3Up-regulated spinal microRNAs induce aggregation of superoxide dismutase 1 protein in canine degenerative myelopathy.Reviewed

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    DOI: 10.1016/j.rvsc.2020.

  • Islam MS, Shinya U, Takagi M, Akahoshi T, Yabuki A, Pervin S, Rakib TM, Rahman MM, Tacharina MR, Yamato O*. .  Carrier rate of the c.235G>C mutation in the bovine isoleucyl-tRNA synthetase (IARS) gene of Japanese Black cows at Kagoshima prefecture, Japan, and analysis of the metabolic profiling and reproductive performance of heterozygous cows. .  J Vet Med Sci83 ( 2 ) 254 - 259   2021.2Carrier rate of the c.235G>C mutation in the bovine isoleucyl-tRNA synthetase (IARS) gene of Japanese Black cows at Kagoshima prefecture, Japan, and analysis of the metabolic profiling and reproductive performance of heterozygous cows.Reviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1292/jvms.20-0356

  • Okawa H, Wijayagunawardane MMP, Vos PLAM, Yamato O, Taniguchi M, Takagi M*. .  Effects of intrauterine infusion of a chitosan solution on recovery and subsequent reproductive performance of early postpartum dairy cows with endometritis: a pilot field trial. .  Animals11 ( 1 ) E197   2021.1Effects of intrauterine infusion of a chitosan solution on recovery and subsequent reproductive performance of early postpartum dairy cows with endometritis: a pilot field trial.Reviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3390/ani11010197

  • Shuvo AP, Poddar S, Uddin M, Ahasan ASML, Das PK, Islam MS, Uddin MM, Yamato O, Faruq AA*. .  Determination of anatomical morphology in proventriculus, proventriculus-gizzard junction, cecum and liver in turkey spp. (Meleagris gallopavo) with histomorphological characteristics of liver for post mortem diagnosis. .  Bangl J Vet Anim Sci8 ( 2 ) 91 - 96   2020.12Determination of anatomical morphology in proventriculus, proventriculus-gizzard junction, cecum and liver in turkey spp. (Meleagris gallopavo) with histomorphological characteristics of liver for post mortem diagnosis.Reviewed

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  • Kobatake Y*, Nishimura N, Sakai H, Iwana S, Yamato O, Nishii N, Kamishina H. .  Long-term survival of a dog with Alexander disease. .  J Vet Med Sci82 ( 11 ) 1704 - 1707   2020.11Long-term survival of a dog with Alexander disease.Reviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1292/jvms.20-0133

  • Sasazaki N, Obi T, Aridome C, Furumoto M, Toda K, Hasunuma H, Matsumoto D, Okawa H, Yamato O, Igari N, Kazami D, Taniguchi M, Takagi M*. .  Effects of dietary feed supplementation of heat-treated Lactobacillus sakei HS-1 on the health status, blood parameters, and fecal microbial flora of Japanese Black calves. .  J Vet Med Sci82 ( 10 ) 1428 - 1435   2020.10Effects of dietary feed supplementation of heat-treated Lactobacillus sakei HS-1 on the health status, blood parameters, and fecal microbial flora of Japanese Black calves.Reviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1292/jvms.20-0181

  • Furusawa Y, Takahashi M, Shima-Sawa M, Yamato O, Yabuki A*. .  Argyrophilic nucleolar organizer regions staining for cytology smears in dogs and cats. .  J Vet Med Sci82 ( 9 ) 1267 - 1270   2020.9Argyrophilic nucleolar organizer regions staining for cytology smears in dogs and cats.Reviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1292/jvms.20-0271

  • Kimura S, Kamatari YO, Kuwahara Y, Hara H, Yamato O, Maeda S, Kamishina H, Honda R*. .  Canine SOD1 harboring E40K or T18S mutations promotes protein aggregation without reducing the global structure stability. .  PeerJ8   e9512   2020.7Canine SOD1 harboring E40K or T18S mutations promotes protein aggregation without reducing the global structure stability.Reviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.7717/peerj.9512

  • Yabuki A*, Uehara Y, Ichii O, Yoshida C, Yamato O. .  Expression of peroxisome proliferator-activated receptor γ in the kidneys of felines with chronic kidney disease. .  J Comp Pathol176   81 - 85   2020.4Expression of peroxisome proliferator-activated receptor γ in the kidneys of felines with chronic kidney disease.Reviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.jcpa.2020.02.007

  • Masuko A, Maehara S*, Hayashi M, Kato R, Shimode A, Yamato O, Nakade T .  Indocyanine green angiography findings with Collie eye anomaly in Hokkaido dogs .  Jpn J Vet Res68 ( 1 ) 13 - 20   2020.2Indocyanine green angiography findings with Collie eye anomaly in Hokkaido dogsReviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.14943/jjvr.68.1.9

  • Shinya U, Yamato O, Sato S, Kajisa M, Takagi M*. .  Metabolic profile of Japanese Black breeding cattle herds: its usefulness in the detection of abnormal metabolism resulting from high protein diets. .  Anim Nutr Feed Technol20 ( 1 ) 1 - 12   2020.1Metabolic profile of Japanese Black breeding cattle herds: its usefulness in the detection of abnormal metabolism resulting from high protein diets.Reviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.5958/0974-181X.2020.00001.3

  • Hashem MA, Kayesh MEH, Yamato O, Maetani F, Eiei T, Mochizuki K, Sakurai H, Ito A, Kannno H, Kasahara T, Amano Y, Tsukiyama-Kohara K*. .  Coinfection with koala retrovirus subtypes A and B and its impact on captive koalas in Japanese zoos. .  Arch Virol164 ( 11 ) 2735 - 2745   2019.11Coinfection with koala retrovirus subtypes A and B and its impact on captive koalas in Japanese zoos.Reviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00705-019-04392-w

  • Lestari TD*, Ismudiono I, Sardjito T, Yamato O*, Takagi M, Yabuki A, Srianto P. .  Breeding performance of Indonesian beef cattle as recipients for embryo transfer. .  J Vet Med Sci81 ( 11 ) 1688 - 1691   2019.11Breeding performance of Indonesian beef cattle as recipients for embryo transfer.Reviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1292/jms.19-0429

  • Ohara Y, Yabuki A*, Nakamura R, Ichii O, Mizukawa H, Yokoyama N, Yamato O. .  Renal infiltration of macrophages in canine and feline chronic kidney disease. .  J Comp Pathol170   53 - 59   2019.7Renal infiltration of macrophages in canine and feline chronic kidney disease.Reviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.jcpa.2019.05.006

  • Nakata K, Heisima K, Sakai H, Yamato O, Furusawa Y, Nishida H, Maeda S, Kamishina H*. .  Plasma microRNA miR-26b as a potential diagnostic biomarker of degenerative myelopathy in Pembroke Welsh Corgis. .  BMC Vet Res15 ( 1 ) 192   2019.6Plasma microRNA miR-26b as a potential diagnostic biomarker of degenerative myelopathy in Pembroke Welsh Corgis.Reviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1186/s12917-019-1944-3

  • Villani NA, Bullock G, Michaels JR, Yamato O, O’Brien DP, Mhlanga-Mutangadura T, Johnson GS, Katz ML*. .  A mixed breed dog with neuronal ceroid lipofuscinosis is homozygous for a CLN5 nonsense mutation previously identified in Border Collies and Australian Cattle Dogs. .  Mol Genet Metab127 ( 1 ) 107 - 115   2019.5Reviewed International journal

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:Elsevier BV  

    DOI: 10.1016/j.ymgme.2019.04.003

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    PubMed

  • Kayesh MEH, Yamato O, Rahman MM, Hashem MA, Maetani F, Eiei T, Mochizuki K, Sakurai H, Tsukiyama-Kohara K*. .  Molecular dynamics of koala retrovirus infection in captive koalas in Japan. .  Arch Virol164 ( 3 ) 757 - 765   2019.3Molecular dynamics of koala retrovirus infection in captive koalas in Japan.Reviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00705-019-04149-5

  • Okawa H, Goto A, Yamato O, Wijayagunawardan MMP, Vos PLAM, Taniguchi M, Takagi M*. .  Risk factors associated with reproductive performance in Japanese dairy cows: vaginal discharge with flecks of pus or calving abnormality extend time to pregnancy. .  J Vet Med Sci81 ( 1 ) 95 - 99   2019.1Risk factors associated with reproductive performance in Japanese dairy cows: vaginal discharge with flecks of pus or calving abnormality extend time to pregnancy.Reviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1292/jms.18-0259

  • Yokota S, Kobatake Y, Noda Y, Nakata K, Yamato O, Hara H, Sakai H, Nishida H, Maeda S, Kamishina H*. .  Activation of the unfolded protein response in canine degenerative myelopathy. .  Neurosci Lett687   216 - 222   2018.11Activation of the unfolded protein response in canine degenerative myelopathy.Reviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.neulet.2018.09.040

  • Yamato O*, Tsuneyoshi T, Ushijima M, Jikihara H, Yabuki A. .  Safety and efficacy of aged garlic extract in dogs: upregulation of the nuclear factor erythroid 2-related factor 2 (Nrf2) signaling pathway and Nrf2-regulated phase II antioxidant enzymes. .  BMC Vet Res14 ( 1 ) 373   2018.11Safety and efficacy of aged garlic extract in dogs: upregulation of the nuclear factor erythroid 2-related factor 2 (Nrf2) signaling pathway and Nrf2-regulated phase II antioxidant enzymes.Reviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1186/s12917-018-1699-2

  • Yabuki A*, Hamamoto T, Rahman MM, Yamato O. .  Changes in lectin-binding patterns in the kidneys of canines with immune-complex mediated glomerulonephritis. .  J Vet Med Sci80 ( 10 ) 1562 - 1566   2018.10Changes in lectin-binding patterns in the kidneys of canines with immune-complex mediated glomerulonephritis.Reviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1292/jms.18-0331

  • Sawa M, Yabuki A*, Kohyama M, Miyoshi N, Yamato O. .  Rapid multiple immunofluorescent staining for the simultaneous detection of cytokeratin and vimentin in the cytology of canine tumors. .  Vet Clin Pathol47 ( 2 ) 326 - 332   2018.6Rapid multiple immunofluorescent staining for the simultaneous detection of cytokeratin and vimentin in the cytology of canine tumors.Reviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/vcp.12598

  • Toda K, Uno S, Kokushi E, Shiiba A, Hasunuma H, Matsumoto D, Ohtani M, Yamato O, Shinya U, Wijayagunawardane MPB, Fink-Gremmels J, Taniguchi M, Takagi M*. .  Fructo-oligosaccharides (DFA III) feed supplementation for mitigation of mycotoxin exposure in cattle – clinical evaluation by a urinary zearalenone monitoring system. .  Toxins10 ( 6 ) E223   2018.6Fructo-oligosaccharides (DFA III) feed supplementation for mitigation of mycotoxin exposure in cattle – clinical evaluation by a urinary zearalenone monitoring system.Reviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3390/toxins10060223

  • Nakamura R, Yabuki A*, Ichii O, Mizukawa H, Yokoyama N, Yamato O. .  Changes in renal peritubular capillaries in canine and feline chronic kidney disease. .  J Comp Pathol160   79 - 83   2018.4Changes in renal peritubular capillaries in canine and feline chronic kidney disease.Reviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.jcpa.2018.03.004

  • Ito D*, Ishikawa C, Jeffery ND, Ono K, Uchida K, Yamato O, Kitagawa M. .  Two-year follow-up magnetic resonance imaging and spectroscopy findings and cerebrospinal fluid analysis of a dog with Sandhoff’s disease. .  J Vet Intern Med32 ( 2 ) 797 - 804   2018.3Two-year follow-up magnetic resonance imaging and spectroscopy findings and cerebrospinal fluid analysis of a dog with Sandhoff’s disease.Reviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/vim.15041

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Books

  • 犬の内科診療 Part 3

    大和修, 宇塚雄次.(代謝性脳症)

    緑書房  2021.3  ( ISBN:978-4-89531-585-2

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    Responsible for pages:208–217  

MISC

  • 動物の遺伝子疾患 第6回 ボーダー・コリーの遺伝子疾患

    大和修

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  • 品種によって異なる遺伝的形質:ボーダー・コリーの遺伝子疾患

    大和修

    KUVHS News Letter   第14号   6 - 7   2021.7

  • 動物の遺伝子疾患 第5回 サンドホフ病(GM2ガングリオシドーシス0バリアント)

    大和修

    KAKE-HASHI   24   14 - 18   2021.4