Updated on 2025/12/12

写真a

 
MISUMI Kazuhiro
 
Organization
Research Field in Veterinary Medicine, Agriculture, Fisheries and Veterinary Medicine Area Joint faculty of Veterinary Medicine Joint Department of Veterinary Medicine Professor
Title
Professor

Degree

  • 博士(獣医学) ( 1995.3   山口大学 )

  • 農学修士 ( 1988.3   鹿児島大学 )

  • 農学士 ( 1986.3   鹿児島大学 )

Research Interests

  • horse

  • bone and cartilage

  • Joint

  • musculoskeletal system

Research Areas

  • Others / Others  / 獣医外科学

Education

  • Yamaguchi University

    1991.4 - 1995.3

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    Country: Japan

  • Kagoshima University

    1986.4 - 1988.3

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    Country: Japan

  • Kagoshima University

    1982.4 - 1986.3

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    Country: Japan

Research History

  • Kagoshima University   Professor

    2024.4

  • Kagoshima University   Manager(Dean)

    2020.4 - 2024.3

  • Kagoshima University   Professor

    2012.4

  • Kagoshima University   Professor

    2006.4 - 2012.3

  • Kagoshima University   Associate Professor (as old post name)

    2000.10 - 2006.3

  • Kagoshima University   Lecturer

    1996.9 - 2000.9

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Professional Memberships

  • 日本再生医療学会

    2015.3

  • 日本軟骨代謝学会

    2002.10

  • 日本ウマ科学会

    2001.10

  • 日本リウマチ学会

    2001.10

  • 日本獣医師会 日本産業動物獣医学会

    1989.4

  • 日本獣医学会

    1987.10

  • American Association of Equine Practitioners

    2002 - 2018

  • 日本獣医麻酔外科学会

    1992.10

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Committee Memberships

  • 日本学術振興会学術システム研究センター   専門研究員  

    2020.4 - 2024.3   

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    Committee type:Academic society

  • 大学改革支援・学位授与機構   国立大学教育研究評価委員会専門委員  

    2020.2 - 2023.6   

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    Committee type:Academic society

  • 大学基準協会   獣医学教育評価委員会委員  

    2019.4   

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    Committee type:Academic society

  • 大学基準協会   獣医学教育評価検討委員会委員  

    2013.4 - 2015.3   

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    Committee type:Other

  • 獣医学教育の改善・充実に関する調査研究協力者会議   委員  

    2012.3 - 2015.3   

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    Committee type:Government

  • 特定非営利活動法人 獣医学系大学間獣医学 教育支援機構   理事  

    2020.4 - 2024.3   

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    Committee type:Academic society

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Studying abroad experiences

  • 1998.5 - 1999.5   University of Liverpool, School of Veterinary Medicine   Visiting Researcher

 

Papers

  • Koga Y, Fujiki M, Hifumi T, Moriwaki E, Chiba S, and Misumi K .  A preliminary study of synovial fluid-derived mesenchymal stromal cell therapy for canine osteoarthritis .  Research in Veterinary Science 196   105897   2025.9Reviewed

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    Authorship:Last author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.rvsc.2025.105897

  • Yamasaki A, Kunitomi Y, Murata D, Sunaga T, Kuramoto T, Sogawa T, Misumi K .  Osteochondral regeneration using constructs of mesenchymal stem cells made by bio three-dimensional printing in mini-pigs .  Journal of orthopaedic research : official publication of the Orthopaedic Research Society 37 ( 6 ) 1398 - 1408   2019.6Reviewed

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    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/jor.24206

    PubMed

  • Murata D, Miyakoshi D, Hatazoe T, Miura N, Tokunaga S, Fujiki M, Nakayama K, and Misumi K .  Multipotency of equine mesenchymal stem cells derived from synovial fluid .  The Veterinary Journal 202   53 - 61   2014.10Reviewed

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    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

  • Misumi K, Tagami M, Kamimura T, Miyakoshi D, Helal IE, Arai K, and Fujiki M .  Urine cartilage oligomeric matrix protein (COMP) measurement is useful in discriminating the osteoarthritic Thoroughbreds .  Osteoarthritis Cartilage 14 ( 11 ) 1174 - 1180   2006.11Reviewed

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    Authorship:Lead author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

  • Misumi K, Vilim V, Clegg PD, Thompson CCM, and Carter SD .  Measurement of cartilage oligomeric matrix protein (COMP) in normal and diseased equine synovial fluids .  Osteoarthritis Cartilage 9   119 - 127   2001.2Reviewed International coauthorship

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  • Misumi K, Sakamoto H, and Shimizu R .  Changes in blood lactate and heart rate in thoroughbred horses during swimming and running according to their stage of training .  Veterinary Record 135   226 - 228   1994.9Reviewed

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  • Yamashita N, Hatazoe T, Misumi K, and Hobo S. .  Hematological and blood biochemical parameters of Tokara horses in Kaimon Foothills Nature Park. .  The Journal of Veterinary Medical Science   2025.10Reviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1292/jvms.25-0340.

  • Mihara K, Kanemoto I, Sato K, Yasuhira Y, Watanabe I, Suzuki Y, Nagura J, and Misumi K .  Effects of mitral valve repair on valvular geometry and hemodynamics in dogs with myxomatous mitral valve disease .  Veterinary Surgery 53   415 - 425   2024.3Reviewed

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    Authorship:Last author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/vsu.14068.

  • Sogawa T, Yamaguchi F, Misumi K, and Fujiki M .  Evaluation of cortical bone strength using a quantitative ultrasound measurement device in dogs .  Journal of Vterinary Medical Science 86   325 - 3332   2024.3Reviewed

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    Language:English  

  • Mihara K, Kanemoto I, Sato K, Yasuhira Y, Watanabe I, and Misumi K .  Echocardiographic evaluation of deformity and enlargement of the canine mitral valve annulus associated with myxomatous degenerative mitral valve disease .  Journal of Veterinary Cardiology 37   8 - 17   2021.10Reviewed

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    Authorship:Last author   Language:English   Publishing type:Research paper (scientific journal)  

    Other Link: https://doi.org/10.1016/j.jvc.2021.08.002.

  • Yamaguchi F, Nishi H, Misumi K, and Fujiki M .  Serum cross-linked N-telopeptide of type I collagen across the canine life span: An investigation in intact and neutered male and female dogs .  Research in Veterinary Science 20   609 - 615   2021.4Reviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.rvsc.2021.04.008.

  • Hatai H, Hatazoe T, Seo H, Tozaki T, Ishikawa S, Miyoshi N, Misumi K, and Hobo S .  Primary sinonasal malignant melanoma with systemic metastasis in a non-gray horse .  Journal of Veterinary Diagnostic Investigation 8 ( 2 ) 1040638720 - 383   2020.12Reviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1177/1040638720978561

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  • Yamaguchi F, Nishi H, Kuramoto T, Saitoh Y, Sogawa T, Misumi K, Fujiki M .  Relationship between serum estradiol, cathepsin K, and N-telopeptide of type I collagen in female dogs .  Research in Veterinary Science 130   133 - 138   2020.6Reviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.rvsc.2020.03.015

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  • Senokuchi A, Ishikawa S, Tozaki T., Takasu M, Kakoi H, Misumi K, and Hobo S .  Genetic analyses for conservation of the traditional Tokara horse using 31 microsatellite markerss. .  Journal of Equine Science 29 ( 4 ) 97 - 104   2018.12Reviewed

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  • Yamasaki A, Omura T, Murata D, Kobayashi M, Sunaga T, Kusano K, Ueno Y, Kuramoto T, Hobo S, Misumi K .  A pilot study of regenerative therapy by implanting synovium-derived mesenchymal stromal cells in equine osteochondral defect models .  Journal of Equine Science 29 ( 4 ) 117 - 122   2018.12Reviewed

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    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1294/jes.29.117

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  • Ishikawa S, Horinouchi C, Mizoguchi R, Senokuchi A, Kamikakimoto R, Murata D, Hatazoe T, Tozaki T, Misumi K, Hobo S .  Isolation of equine peripheral blood stem cells from a Japanese native horse .  Journal of Equine Science 28 ( 4 ) 153 - 158   2017.12Reviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1294/jes.28.153

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  • Miyakoshi D, Senba H, Shikichi M, Maeda M, Shibata R, Misumi K .  A retrospective study of radiographic abnormalities in the repositories for Thoroughbreds at yearling sales in Japan .  The Journal of Veterinary Medical Science 79 ( 11 ) 1807 - 1814   2017.11Reviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1292/jvms.16-0425

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  • Murata D, Akieda S, Misumi K, Nakayama K .  Osteochondral regeneration with a scaffold-free three-dimensional construct of adipose tissue-derived mesenchymal stromal cells in pigs .  Tissue Engineering Regenerative Medicine 15   101 - 113   2017.11Reviewed

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  • Ishikawa S, Horinouchi C, Murata D, Matsuzaki S, Misumi K, and Hobo S .  Isolation and characterization of equine dental pulp stem cells derived from Thoroughbred wolf teeth .  Journal of Veterinary Medical Science 79   47 - 51   2017.1Reviewed

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  • Murata D, Yamasaki A, Matsuzaki S, Sunaga T, Fujiki M, Tokunaga S, and Misumi K .  Characteristics and multi-potency of equine dedifferentiated fat cells .  Journal of Equine Science 27   57 - 65   2016.6Reviewed

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    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

  • Miyakoshi D, Senba H, Shibata R, Shikiti M, Maeda M, and Misumi K .  A retrospective study of limb abnormalities in a radiographic repository at Thoroughbred training sales in Japan .  Journal of Equine Science 27   67 - 76   2016.6Reviewed

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  • Hatazoe T, Endo Y, Iwamoto Y, Korosue K, Kuroda T, Inoue S, Murata D, Hobo S, and Misumi K .  A study of the distribution of color Doppler flows in the superficial digital flexor tendon of young Thoroughbreds during their training periods .  Journal of Equine Science 26   99 - 104   2015.12Reviewed

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  • Hatazoe T, Kawaguchi H, Hobo S, and Misumi K .  Pituitary Pars Intermedia Dysfunction (Equine Cushing’s Disease) in a Thoroughbred Stallion: a Single Report .  Journal of Equine Science 26   125 - 128   2015.12Reviewed

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  • Murata D, Tokunaga S, Tamura T, Kawaguchi H, Miyoshi N, Fujiki M, Nakayama K, and Misumi K .  A preliminary study of osteochondral regeneration using a scaffold-free 3-dimensional construct of porcine adipose tissue-derived mesenchymal stem cells .  Journal of Orthopaedic Surgery and Research 10 ( 35 )   2015.5Reviewed

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    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

  • Murata D, Tokunaga S, Tamura T, Kawaguchi H, Miyoshi N, Fujiki M, Nakayama K, Misumi K .  A preliminary study of osteochondral regeneration using a scaffold-free three-dimensional construct of porcine adipose tissue-derived mesenchymal stem cells .  Journal of orthopaedic surgery and research 10   35   2015.3Reviewed

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    Language:English  

    DOI: 10.1186/s13018-015-0173-0

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  • Murata D, Misumi K, and Fujiki M .  A preliminary study of diagnostic color doppler ultrasonography in equine superficial digital flexor tendonitis .  The Journal of Veterinary Medical Science 74 ( 12 ) 1639 - 1642   2012.12Reviewed

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  • 畠添 孝,中西信吾,木村慶純,三角一浩 .  日本の種牡馬の死亡原因に関する回顧的調査 .  日本獣医師会雑誌 65 ( 7 ) 511 - 515   2012.7Reviewed

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

  • Hatazoe T, Kubota C, Fujiki M, and Misumi K .  Mating behavior increases workload of heart in Thoroughbred stallions .  The Journal of Veterinary Medical Science 74 ( 4 ) 423 - 428   2012.4Reviewed

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  • Tokunaga S, Fujiki M, Yabuki A, Misumi K .  Immunohistochemical analysis of cartilage-derived retinoic acid-sensitive protein (CD-RAP)/melanoma inhibitory activity (MIA) in murine, canine, bovine and equine cerebrospinal tissues .  The Journal of veterinary medical science 74 ( 4 ) 523 - 6   2012.4Reviewed

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  • Nagano S, Fujiki M, Tokunaga S, and Misumi K .  Analysis of cartilage oligomeric matrix protein and matrix metalloproteinase-9 in cerebrospinal fluid of miniature dachshund with intervertebral disc herniation .  Research in Veterinary Science 91   482 - 485   2011.12Reviewed

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    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

  • Nagano S, Kim S, Tokunaga S, Arai K, Fujiki M, and Misumi K .  Matrix metalloprotease-9 activity in the cerebrospinal fluid and spinal injury severity in dogs with intervertebral disc herniation .  Research in Veterinary Science 91   482 - 485   2011.11Reviewed

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  • 村田大紀,三浦直樹,松元光春,三好宣彰,藤木 誠,三角一浩 .  馬の頸椎損傷の画像診断例 .  日本獣医師会雑誌 64   703 - 707   2011.9Reviewed

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  • Kawaguchi H, Miyoshi N, Miura N, Fujiki M, Horiuchi M, Izumi Y, Miyajima H, Nagata R, Misumi K, Takeuchi T, Tanimoto A, Yoshida H .  Microminipig, a Non-rodent Experimental Animal Optimized for Life Science Research: Novel Atherosclerosis Model Induced by High Fat and Cholesterol Diet .  Journal of pharmacological sciences 115 ( 2 ) 115 - 121   2011.1Reviewed

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  • Miyoshi N, Horiuchi M, Inokuchi Y, Miyamoto Y, Miura N, Tokunaga S, Fujiki M, Izumi Y, Miyajima H, Nagata R, Misumi K, Takeuchi T, Tanimoto A, Yasuda N, Yoshida H, Kawaguchi H .  Novel microminipig model of atherosclerosis by high fat and high cholesterol diet, established in Japan .  In vivo (Athens, Greece) 24 ( 5 ) 671 - 80   2010.9Reviewed

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  • Moe KK, Yano T, Misumi K, Kubota C, Nibe K, Yamazaki W, Muguruma M, Misawa N .  Detection of antibodies against Fusobacterium necrophorum and Porphyromonas levii-like species in dairy cattle with papillomatous digital dermatitis .  Microbiology and Immunology 54 ( 6 ) 338 - 46   2010.6Reviewed

  • Yabuki A, Mitani S, Fujiki M, Misumi K, Endo Y, Miyoshi N, Yamato O .  Comparative study of chronic kidney disease in dogs and cats: induction of myofibroblasts .  Research in veterinary science 88 ( 2 ) 294 - 9   2010.4Reviewed

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    DOI: 10.1016/j.rvsc.2009.09.003

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  • Moe KK, Yano T, Misumi K, Kubota C, Yamazaki W, Muguruma M, Misawa N .  Analysis of the IgG immune response to Treponema phagedenis-like spirochetes in individual dairy cattle with papillomatous digital dermatitis .  Clinical and Vaccine Immunology : CVI 17 ( 3 ) 376 - 83   2010.3Reviewed

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  • Tokunaga S, Yamanokuchi K, Yabuki A, Fujiki M, Misumi K .  Cartilage oligomeric matrix protein in canine spinal cord appears in the cerebrospinal fluid associated with intervertebral disc herniation .  Spine 35 ( 1 ) 4 - 9   2010.1Reviewed

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    Language:English  

    DOI: 10.1097/BRS.0b013e3181b61f14

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  • 村田大紀,井手哲也,矢吹 映,三好宣彰,畠添 孝,藤木 誠,三角一浩 .  扁平上皮癌により眼球摘出した馬の1 例 .  日本獣医師会雑誌 63 ( 12 ) 931 - 934   2010.1Reviewed

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  • Hamamoto T, Yabuki A, Yamato O, Fujiki M, Misumi K, Matsumoto M .  Immunohistochemical analysis of cyclooxygenase-2 induction during wound healing in dog skin .  Research in veterinary science 87 ( 3 ) 349 - 54   2009.12Reviewed

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    DOI: 10.1016/j.rvsc.2009.05.004

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  • Yamanokuchi K, Yabuki A, Yoshimoto Y, Arai K, Fujiki M, and Misumi K .  Gene and protein expression of cartilage oligomeric matrix protein associated with oncogenesis in canine tumors .  The Journal of Veterinary Medical Science 71 ( 4 ) 499 - 503   2009.4Reviewed

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  • Yano T, Yamagami R, Misumi K, Kubota C, Moe KK, Hayashi T, Yoshitani K, Ohtake O, Misawa N .  Genetic heterogeneity among strains of Treponema phagedenis-like spirochetes isolated from dairy cattle with papillomatous digital dermatitis in Japan .  Journal of Clinical Microbiology 47 ( 3 ) 727 - 33   2009.3Reviewed

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  • Yamanokuchi K, Tagami M, Nishimatsu E, Shimizu Y, Hirose Y, Komatsu K, and Misumi K .  Sandwich ELISA system for cartilage oligomeric matrix protein in equine synovial fluid and serum .  Equine Veterinary Journal 41 ( 1 ) 41 - 46   2009.1Reviewed

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  • 畠添 孝, 帆保誠二, 山下紀幸, 小松耕史, 三角一浩 .  腎機能不全を主徴とした馬のレプトスピラ症 .  日本獣医師会雑誌 62   303 - 307   2009.1Reviewed

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    Authorship:Corresponding author   Language:Japanese   Publishing type:Research paper (scientific journal)  

  • Arai K, Tagami M, Hatazoe T, Nishimatsu E, Shimizu Y, Fujiki M, Misumi K .  Analysis of cartilage oligomeric matrix protein (COMP) in synovial fluid, serum and urine from 51 racehorses with carpal bone fracture .  The Journal of veterinary medical science 70 ( 9 ) 915 - 21   2008.9Reviewed

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    Authorship:Corresponding author   Language:English  

    DOI: 10.1292/jvms.70.915

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  • 畠添孝, 藤木誠, 小松耕史, 三角一浩 .  回腸の網嚢孔エントラップメントによる馬の急性腹症手術例 .  日本獣医師会雑誌 61 ( 2 ) 131 - 135   2008.2Reviewed

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  • Fujiki M, Shineha J, Yamanokuchi K, Misumi K, and Sakamoto H .  Effects of treatment with polysulfated glycosaminoglycan on serum cartilage oligomeric matrix protein and C-reactive protein concentrations, serum matrix metalloproteinase-2 and -9 activities, and lameness in dogs with osteoarthritis .  American Journal of Veterinary Research 68 ( 8 ) 827 - 833   2007.8Reviewed

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  • Miwa K, Misumi K, Shimada K, Miyoshi N, Inoue T, Kawabe Y, Moriyama K, Ibara S, Ikenoue T, and Sakamoto H .  A device for adsorbing unbound, unconjugated bilirubin and its effects in vitro and in a hyperbilirubinemic newborn piglet .  Journal of Perinatal Medicine 35 ( 3 ) 232 - 235   2007.3Reviewed

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  • Helal IE, Misumi K, Tateno O, Kodama T, Ishimaru M, Yamamoto J, Miyakoshi D, Fujiki M .  Effect of exercise on serum concentration of cartilage oligomeric matrix protein in Thoroughbreds .  American Journal of Veterinary Research 68 ( 2 ) 134 - 140   2007.2Reviewed

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  • Fujiki M, Kurima Y, Yamanokuchi K, Misumi K, and Sakamoto H .  Computed tomographic evaluation of growth-related changes in the hip joints of young dogs .  American Journal of Veterinary Research 68   730 - 734   2007.1Reviewed

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

  • Fujiki M, Kamiya H, Arai K, Misumi K, and Sakamoto H .  The effects of growth and disease in serum keratin sulfate concentration in dogs .  The Journal of Veterinary Medical Science 68 ( 9 ) 947 - 951   2006.9Reviewed

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  • Setoyama K,Kamimura R, Fujiki M, Misumi K, Miyahara K, Sakamoto H .  Effects of Olprinone on Myocardial Ischemia-Reperfusion Injury in Dogs .  The Journal of Veterinary Medical Science 68 ( 8 ) 865 - 868   2006.8Reviewed

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  • Miya K, Misumi K, Miyoshi N, Arai K, Fujiki M, Kubota C, and Sakamoto H .  Interpreting gelatinase activity in tumor tissue and serum as a prognostic marker of naturally developing canine tumors .  The Journal of Veterinary Medical Science 67 ( 8 ) 769 - 775   2005.8Reviewed

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  • Takahashi T, Une R, Fukushima K, Fujiki M, Misumi K, Miyoshi N, End Y, Ohishi A, and Akuzawa M .  Molecular cloning of canine nm23 cDNAs and their expression in normal and tumor tissues .  The Journal of Veterinary Medical Science 67 ( 8 ) 837 - 841   2005.8Reviewed

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    Institutional Repository URL

  • 保坂善真, 樋口豪紀, 翁長武紀, 永田廣, 上村智希, 三角一浩, 植田弘美, 竹花一成 .  ウマの腱の損傷程度を反映する血清中Ⅰ型コラーゲン架橋N-末端テロペプチド濃度 .  日本獣医師会雑誌 58 ( 3 ) 175 - 179   2005.3Reviewed

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

  • Yamashita T, Moriyama Y, Sata N, Hamada N, Horinouchi T, Amitani S, Miyahara K, Setoyama K, Misumi K, Sakamoto H .  Discrepancy between Doppler and catheter measurements of pressure gradients across small-size prosthetic valve .    53 ( 2 ) 64 - 68   2005.2Reviewed

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

  • Arai K, Misumi K, Carter SD, Shinbara S, Fujiki M, and Sakamoto H .  Analysis of cartilage oligomeric matrix protein (COMP) degradation and synthesis in equine joint disease .  Equine Veterinary Journal 37 ( 1 ) 31 - 36   2005.1Reviewed International coauthorship

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  • Tsuda T, Yoshida K, Ohashi S, Yanase T, Sueyoshi M, Kamimura S, Misumi K, Hamana K, Sakamoto H, Yamakawa M .  Arthrogryposis, hydranencephaly and cerebellar hypoplasia syndrome in neonatal calves resulting from intrauterine infection with Aino virus .  Veterinary Research 35 ( 5 ) 531 - 538   2004.9Reviewed

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  • Fujiki M, Misumi K, Sakamoto H .  Laxity of canine hip joint in two positions with computed tomography .  The Journal of Veterinary Medical Science 66 ( 8 ) 1003 - 1006   2004.8Reviewed

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  • Setoyama K, MISUMI K, and Sakamoto H .  Assessment of Optimal Atrioventricular Delay Using Doppler Index in Atrioventricular Sequential Pacing .  THE JOURNAL of JAPANESE COLLEGE of ANGIOLOGY44 ( ※ ) 103 - 107   2004.1Reviewed

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

  • Setoyama K, Shinzato T, Misumi K, Fujiki M, Sakamoto H .  Effects of propofol-sevoflurane anesthesia on the maternal and fetal hemodynamics blood gases, and uterine activity in pregnant goats .  The Journal of veterinary medical science 65 ( 10 ) 1075 - 81   2003.10Reviewed

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  • Successful use of an acceleration rate response pacemaker with a transvenous steroid-eluting screw-in lead for third-degree atrioventricular block in a labrador retriever .    65 ( 10 ) 1101 - 5   2003.10Reviewed

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  • Miura N, Fujiki M, Miyoshi Y, Misumi K, Sakamoto H .  Steroid injection therapy in a feline solitary bone cyst .  The Journal of veterinary medical science 65 ( 4 ) 523 - 5   2003.4Reviewed

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  • Misumi K, Vilim V, Hatazoe T, Murata T, Fujiki M, Oka T, Sakamoto H, and Carter SD .  Serum level of cartilage oligomeric matrix protein (COMP) in equine osteoarthritis .    34   602 - 606   2002.9Reviewed International coauthorship

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  • Effects of milrinone on hemodynamics and regional blood flow in the hypoxic dog .    64 ( 6 ) 499 - 503   2002.6Reviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1292/jvms.64.499

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  • Immunohistochemical detection of P-glycoprotein (PGP) and multidrug resistance-associated protein (MRP) in canine cutaneous mast cell tumors .    64 ( 6 ) 531 - 3   2002.6Reviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1292/jvms.64.531

    PubMed

  • Misumi K, Vilim V, Carter SD, Ichihashi K, Oka T, and Sakamoto H .  Concentrations of cartilage oligomeric matrix protein in dogs with naturally developing and experimentally induced arthropathy .  American Journal of Veterinary Research 63   598 - 603   2002.4Reviewed International coauthorship

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  • Fujiki M, Misumi K, Sakamoto H .  Evaluation of collagenase-induced mitral valve regurgitation in dogs .  American journal of veterinary research 61 ( 12 ) 1593 - 8   2000.12Reviewed

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    DOI: 10.2460/ajvr.2000.61.1593

    PubMed

  • Misumi K, Fujiki M, Miura N, Sakamoto H .  Uterine horn torsion in two non-gravid bitches .  The Journal of small animal practice 41 ( 10 ) 468 - 71   2000.10Reviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/j.1748-5827.2000.tb03144.x

    PubMed

  • The risk of contrast media-induced ventricular fibrillation is low in canine coronary arteriography with ioxilan .    62 ( 4 ) 421 - 6   2000.4

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1292/jvms.62.421

    PubMed

  • Miura N, Suzuki S, Hamada Y, Kamimura R, Fujiki M, Misumi K, Sakamoto H .  Salt water promotes hypertension in Dahl-S rats .  Experimental animals48 ( 4 ) 289 - 92   1999.10Reviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1538/expanim.48.289

    PubMed

  • Regional blood flow distribution from the proximal arterial cannula during veno-arterial extracorporeal membrane oxygenation in neonatal dog .    61 ( 4 ) 311 - 5   1999.4Reviewed

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    Language:English  

    DOI: 10.1292/jvms.61.311

    PubMed

  • Development of atherosclerotic lesions in cholesterol-loaded rabbits .    48 ( 1 ) 1 - 7   1999.1Reviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1538/expanim.48.1

    PubMed

  • Circulatory arrest under hypothermic anesthesia using abdominal cavity cooling .    60 ( 11 ) 1237 - 42   1998.11

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1292/jvms.60.1237

    PubMed

  • The effects of medetomidine on maternal and fetal cardiovascular and pulmonary function, intrauterine pressure and uterine blood flow in pregnant goats .    46 ( 1 ) 67 - 73   1997.1Reviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1538/expanim.46.67

    PubMed

  • Hirakawa A, Sakamoto H, Misumi K, Nozaki S, Kamimura T and Shimizu R .  Evaluation of pulmonary vasodilatory capacity with inhaled nitric oxide in a dog with patent ductus arteriosus .  The Journal of Veterinary Medical Science 58   673 - 675   1996.7Reviewed

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  • Hirakawa A, Sakamoto H, Misumi K, Kamimura T and Shimizu R .  Effects of inhaled nitric oxide on hypoxic pulmonary vasoconstriction in dogs and a case report of venae cavae syndrome .  The Journal of Veterinary Medical Science 58   551 - 553   1996.6Reviewed

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  • Effects of antihypertensive drugs on maternal and fetal hemodynamics and uterine blood flow in pregnant goats--comparison of nicardipine and labetalol .    58 ( 6 ) 515 - 9   1996.6Reviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1292/jvms.58.515

    PubMed

  • Sakamoto H, Kubota C and Misumi K .  Relationship between arterial and end-tidal carbon dioxide pressure during controlled ventilation in porcine neonates .  Experimental Animal45   195 - 198   1996.4Reviewed

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  • Sakamoto H, Misumi K, Nakama M and Aoki Y .  The effects of xylazine on intrauterine pressure, uterine blood flow, maternal and fetal cardiovascular and pulmonary function in pregnant goats .  The Journal of Veterinary Medical Science 58   211 - 217   1996.3Reviewed

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  • Sakamoto H, Nozaki S, Misumi K, Kurose M, Sohara H, Amitani S and Miyahara K .  Smooth muscle cell proliferation in the arterial intima after stretch injury: Relationship between the severity of stretching and intima hyperplasia in New Zealand white rabbits .  Experimental Animal45   89 - 93   1996.1Reviewed

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    Language:English   Publishing type:Research paper (scientific journal)  

  • Misumi K, Sakamoto H and Shimizu R .  Changes in skeletal muscle composition in response to swimming training for young horses .  The Journal of Veterinary Medical Science 57   959 - 961   1995.10Reviewed

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    Authorship:Lead author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

  • 三角一浩 .  育成馬の運動法と調教法改善に関する研究 .      1995.3

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    Language:Japanese   Publishing type:Doctoral thesis  

  • Misumi K, Hirakawa A, Sakamoto H and Shimizu R .  Principal component analysis, using the measurements during running and swimming test, in thoroughbred horses .  The Journal of Veterinary Medical Science 56   1075 - 1080   1994.12Reviewed

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    Authorship:Lead author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

  • Misumi K, Sakamoto H and Shimizu R .  The validity of swimming training for two-year-old thoroughbreds .  The Journal of Veterinary Medical Science 56   217 - 222   1994.4Reviewed

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    Authorship:Lead author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

  • キシラジンの山羊血行動態および子宮筋におよぼす影響 .      1988.3Reviewed

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    Language:Japanese   Publishing type:Master’s thesis  

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Books

  • 獣医学教育モデル・コア・カリキュラム準拠「馬臨床学 第2版」

    三角一浩、帆保誠二、南保泰雄 他( Role: Supervisor (editorial) ,  馬の超音波検査、運動器病、泌尿器病、神経病、消化器疾患)

    緑書房  2024.7  ( ISBN:978-4-89531-986-7

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    Total pages:342   Responsible for pages:82-83, 148-162, 191-202, 201-209, 248-257   Language:Japanese Book type:Textbook, survey, introduction

  • 獣医外科学

    佐々木信雄、嶋田照雅、西村亮平、奥村正裕、三角一浩、中市統三( Role: Joint editor ,  運動器の外科疾患)

    文英堂  2023.12  ( ISBN:978-4-254-46039-1

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    Total pages:717   Responsible for pages:390~411   Language:Japanese Book type:Textbook, survey, introduction

  • 獣医内科学第3版(大動物編)

    ( Role: Contributor ,  骨関節疾患、脊髄疾患、末梢神経疾患)

    文永堂出版  2022.4 

  • 馬臨床学コアテキスト

    兼子樹廣、佐々木直樹、南保泰雄、樋口徹、三角一浩、和田信也( Role: Contributor)

    緑書房出版  2014.4 

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    Total pages:12-49   Language:Japanese Book type:Textbook, survey, introduction

Presentations

  • Murata D, Tokunaga S, Akieda S, Nakayama K, Setoyama K, Fujiki M, and Misumi K   Osteochondral regeneration of the loading-bearing site using a scaffold-free 3D construct of swine AT-MSCs   International conference

    The 13th ICRS (International Cartilage Repair Society) World Congress  2016.9  International Cartilage Repair Society

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    Event date: 2016.9

    Language:English   Presentation type:Oral presentation (general)  

    Venue:Sorrent, Italy   Country:Italy  

  • Yamasaki A, Matsuzaki S, Murata D, Sunaga T, Tantan S, Kunitomi Y, Harada K, Nakayama K, and Misumi K   Osteochondral regeneration by implanting a scaffold-free 3D construct of swine AT-MSCs using a bio 3D printer   International conference

    The 13th ICRS (International Cartilage Repair Society) World Congress  2016.9  International Cartilage Repair Society

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    Event date: 2016.9

    Language:English   Presentation type:Poster presentation  

    Venue:Sorrent, Italy   Country:Italy  

  • Murata D, Tokunaga S, Akieda S, Fujiki M, Nakayama K, and Misumi K   Osteochondral regeneration using a scaffold free three-dimentional construct of swine adipose tissue- derived mesenchymal stem cells   International conference

    The 4th TERMIS (Tissue Engineering and Regenerative Medicine  2015.9 

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    Event date: 2015.9

    Language:English   Presentation type:Oral presentation (general)  

    Venue:Boston, USA  

  • Murata D, Akieda S, Misumi K, and Nakayama S   Osteochondral regeneration with scaffold free 3D-structure consisting of adipose tissue-derived mesenchymal stem cells in pigs   International conference

    The 12th ICRS (International Cartilage Repair Society) World Congress  2015.5 

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    Event date: 2015.5

    Language:English   Presentation type:Oral presentation (general)  

    Venue:Chicago, USA   Country:United States  

  • Murata D, Tokunaga S, Tamura T, Kawaguchi H, Fujiki M, Miyoshi N, Nakayama K, Misumi K   Osteochondral regeneration with scaffold free 3D-structureof swine adipose tissue-derived mesenchymal stem cells   International conference

    International Cartilage Repair Society   2013.9  International Cartilage Repair Society

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    Event date: 2013.9

    Language:English   Presentation type:Oral presentation (general)  

    Venue:Izmir, Turkey   Country:Turkey  

  • 村田 大紀,秋枝 静香,三角 一浩,中山 功一   ブタ脂肪幹組織由来間葉系幹細胞による骨軟骨再生  

    第14回日本再生医療学会総会  2015.3  第14回日本再生医療学会総会

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    Event date: 2015.3

    Language:Japanese  

    Venue:横浜市  

    国内学会

  • 村田 大紀,德永 暁,宮越 大輔,畠添 孝,三浦 直樹,藤木 誠,中山 功一,三角 一浩   ウマ滑液由来間葉系幹細胞の培養とその性質  

    第157回日本獣医学会  2014.9  第157回日本獣医学会

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    Event date: 2014.9

    Language:Japanese  

    Venue: 札幌市  

    国内学会

  • 三角一浩   ブタ間葉系幹細胞による骨軟骨再生  

    平成25年度 日本獣医師会獣医学術学会年次大会  平成25年度 日本獣医師会獣医学術学会年次大会

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    Event date: 2014.2

    Language:Japanese  

    Venue:千葉  

    国内学会

  • 村田 大紀,德永 暁,田村 忠士,川口 博明, 藤木 誠,三好 宣彰,中山 功一,三角 一浩   ブタの脂肪組織由来間葉系幹細胞による骨軟骨再生  

    第156回日本獣医学会  2013.9  第156回日本獣医学会

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    Event date: 2013.9

    Language:Japanese  

    Venue:岐阜市  

    国内学会

  • 村田大紀,德永 暁,田村 忠,藤木 誠,川口博明,三好宣影,中山功一,三角一浩   ブタ脂肪組織由来間葉系幹細胞の骨軟骨再生  

    第12回日本再生医療学会  2013.3  第12回日本再生医療学会

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    Event date: 2013.3

    Language:Japanese  

    Venue:横浜  

    国内学会

  • 村田大紀,徳永 暁,宮越大輔,藤木 誠,三角一浩.   ウマ滑液由来間葉系幹細胞の分離と培養  

    第153回日本獣医学会  第153回日本獣医学会

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    Event date: 2012.3

    Language:Japanese  

    Venue:さいたま市大宮  

    国内学会

  • 村田大紀,佐藤 隆祐,金 善煕,藤木 誠,三角一浩   馬の頸椎損傷に対する画像検査の1例  

    第23回日本ウマ科学会  第23回日本ウマ科学会

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    Event date: 2010.12

    Language:Japanese  

    Venue:東京  

    国内学会

  • 畠添 孝, 遊佐 繁基, 中西 信吾, 木村 慶純, 窪田 力, 三角一浩   サラブレッド種牡馬におけるホルター心電計を用いた交配時心電図測定  

    第150回日本獣医学会  第150回日本獣医学会

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    Event date: 2010.9

    Language:Japanese  

    Venue:帯広  

    国内学会

  • 坂本 英一,佐藤 隆祐,金 善煕,藤木 誠,三角一浩   馬滑液中のcartilage derived retinoic acid sensitive protein (CD-RAP) / melanoma inhibitory activity (MIA)の測定  

    第22回日本ウマ科学会  第22回日本ウマ科学会

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    Event date: 2009.12

    Language:Japanese  

    Venue:東京  

    国内学会

  • 山之口和人,矢吹 映,藤木 誠,三角一浩   免疫電子顕微鏡的手法を用いた犬の乳腺腫瘍細胞で産生されるCartilage oligomeric matrix proteinの検討  

    第148回日本獣医学会  第148回日本獣医学会

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    Event date: 2009.9

    Language:Japanese  

    Venue:鳥取  

    国内学会

  • 藤木 誠,峰原友香,喜多亜希子,徳永 暁,山之口和人,新井 恒,矢吹 映,樋口雅仁,三角一浩   犬の同種保存皮質骨移植における組織学的および強度解析に関する検討  

    第148回日本獣医学会  第148回日本獣医学会

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    Event date: 2009.9

    Language:Japanese  

    Venue:鳥取  

    国内学会

  • 新井 恒,矢吹 映,三好宣彰,帆保誠二,藤木 誠,三角一浩   ウマのリンパ腫の一例  

    第21回日本ウマ科学会  第21回日本ウマ科学会

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    Event date: 2008.12

    Language:Japanese  

    Venue:東京  

    国内学会

  • 金城亜紀子,宇都直子,瀬戸山健太郎,新井恒,三角一浩   モデル動物を用いた反応性関節炎における軟骨基質分子マーカーの変化  

    第146回日本獣医学会  第146回日本獣医学会

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    Event date: 2008.9

    Language:Japanese  

    Venue:宮崎  

    国内学会

  • 徳永暁,山之口和人,矢吹映,藤木誠,三角一浩   脊髄損傷を診断する細胞外基質分子マーカーの検討  

    第146回日本獣医学会  第146回日本獣医学会

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    Event date: 2008.9

    Language:Japanese  

    Venue:宮崎  

    国内学会

  • 山之口和人, 広瀬遥子, 田上正明, 三角一浩   ウマの滑液および血清中のcartilage oligomeric matrix protein(COMP)定量のためのSandwich ELISA法の開発  

    第20回日本ウマ科学会  第20回日本ウマ科学会

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    Event date: 2007.11

    Language:Japanese  

    Venue:東京  

    国内学会

  • 新井恒, 田上正明, 藤木誠, 三角一浩   競走馬の手根関節内骨折43症例における滑液・血清・尿中cartilage oligomeric matrix protein(COMP)の評価  

    第144回日本獣医学会学術集会  第144回日本獣医学会学術集会

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    Event date: 2007.9

    Language:Japanese  

    Venue:北海道  

    国内学会

  • 三角一浩   競走馬の運動器を守る 2 関節疾患を予測する~どこから病気は始まる?  

    第144回日本獣医学会学術集会  第144回日本獣医学会学術集会

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    Event date: 2007.4

    Language:Japanese  

    Venue:茨城  

    国内学会

  • 三角一浩, 田上正明, 上村智希   関節症マーカーである尿中COMP測定法の改良  

    第19回日本ウマ科学会  第19回日本ウマ科学会

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    Event date: 2006.11

    Language:Japanese  

    Venue:東京  

    国内学会

  • 新井恒, 藤木誠, 三角一浩   尿中cartilage oligomeric matrix protein (COMP)の関節マーカーとしての有用性  

    第142回日本獣医学会学術集会  第142回日本獣医学会学術集会

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    Event date: 2006.9

    Language:Japanese  

    Venue:山口  

    国内学会

  • I.E. Helal, 松本康宏, 石丸睦樹, 山本純也, 三角一浩   育成馬における運動前後の血清cartilage Oligomeric Matrix Protein (COMP)濃度の変動  

    第142回日本獣医学会学術集会  第142回日本獣医学会学術集会

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    Event date: 2006.9

    Language:Japanese  

    Venue:山口  

    国内学会

  • 山之口和人, 藤木誠, 三角一浩   犬の乳腺腫瘍とmelanoma inhibitory activity (MIA)発現との関係  

    第142回日本獣医学会学術集会  第142回日本獣医学会学術集会

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    Event date: 2006.9

    Language:Japanese  

    Venue:山口  

    国内学会

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Research Projects

  • 自己由来間葉系幹細胞による馬の関節手術フォローアップ治療プログラムの開発

    2023.4

    日本学術振興会  科学研究費  基盤研究(B)

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\14400000 ( Direct Cost: \1008000 、 Indirect Cost:\4320000 )

  • 体性幹細胞の高密度培養と大量自家移植による骨軟骨再生技術の開発

    2019.4 - 2022.3

    日本学術振興会  科学研究費補助金  基盤研究(B)

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\13700000 ( Direct Cost: \9590000 、 Indirect Cost:\4110000 )

  • 体性幹細胞の同種他家移植による新たな骨軟骨再生治療法の開発

    2015.4 - 2018.3

    日本学術振興会  科学研究費補助金  基盤研究(B)

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\13100000 ( Direct Cost: \9170000 、 Indirect Cost:\3930000 )

  • 滑液及び滑膜由来間葉系幹細胞の関節内注射による軟骨再生治療試験

    2013.4 - 2015.3

    日本学術振興会  科学研究費補助金  挑戦的萌芽研究

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\3500000 ( Direct Cost: \2450000 、 Indirect Cost:\1050000 )

  • 骨軟骨欠損モデル動物を用いた次世代骨軟骨再生医療の検討

    2011.4 - 2014.3

    日本学術振興会  科学研究費補助金  基盤研究(B)

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\14300000 ( Direct Cost: \10010000 、 Indirect Cost:\4290000 )

  • 脳脊髄液中のマーカー蛋白に基づく,犬椎間板ヘルニアの脊髄損傷診断法の開発

    2008.4 - 2010.3

    日本学術振興会  科学研究費補助金  挑戦的萌芽研究

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\3500000 ( Direct Cost: \2450000 、 Indirect Cost:\1050000 )

  • COMP断片化とMMP活性に基づく,関節疾患の分子病態学的研究

    2007.4 - 2010.3

    日本学術振興会  科学研究費補助金  基盤研究(B)

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    Grant type:Competitive

    Grant amount:\15900000 ( Direct Cost: \11130000 、 Indirect Cost:\4770000 )

  • 関節マトリックス破壊マーカーとしての尿中COMPの解析

    2004.4 - 2007.3

    日本学術振興会  科学研究費補助金  基盤研究(B)

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\10600000 ( Direct Cost: \7420000 、 Indirect Cost:\3180000 )

  • COMPの関節疾患診断マーカーとしての確立と応用

    2000.4 - 2002.3

    日本学術振興会  科学研究費補助金  奨励研究

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\2953000 ( Direct Cost: \2067100 、 Indirect Cost:\885900 )

  • 大型動物細胞による間葉系幹細胞培養の自動培養プラットホーム技術の樹立

    2019.4 - 2020.3

    民間企業  国内共同研究 

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    Authorship:Principal investigator  Grant type:Collaborative (industry/university)

  • 競走馬における血中関節マーカーの解析と臨床意義に関する研究

    2015.4 - 2017.3

    民間企業  国内共同研究 

    三角一浩

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    Authorship:Principal investigator  Grant type:Collaborative (industry/university)

  • バイオ3Dプリンターを用いた高度変性半月板損傷に対するあたらしい再生医療の開発

    2014.4 - 2015.3

    厚生労働科学研究委託費  再生医療実用化研究事業

    三角一浩

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    Authorship:Coinvestigator(s)  Grant type:Competitive

    バイオ3Dプリンターを用いた高度変性半月板損傷に対するあたらしい再生医療の開発

  • 高密度スキャフォールドフリー幹細胞構造体を用いた骨軟骨組織再生の研究

    2013.4 - 2017.3

    サイフューズ  国内共同研究 

    三角一浩

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    Authorship:Principal investigator  Grant type:Collaborative (industry/university)

    「高密度スキャフォールドフリー幹細胞構造体を用いた骨軟骨組織再生の研究

  • 日本中央競馬会受託研究

    2009.4 - 2012.3

    民間企業  一般受託研究 

    三角一浩

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    Authorship:Principal investigator  Grant type:Collaborative (industry/university)

    遺伝子組換え蛋白質抗原を用いた馬レプトスピラ症の血清診断法の確立ならびに疫学調査

  • 日本中央競馬会受託研究

    2008.4 - 2011.3

    民間企業  一般受託研究 

    三角一浩

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    Authorship:Principal investigator  Grant type:Collaborative (industry/university)

    バベシア・カバリ診断用CF抗原の作製に使用する脾臓摘出馬の作製に関する研究

  • 日本小動物栄養学フォーラム

    2004.4 - 2005.3

    民間企業  一般受託研究 

    三角一浩

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    Authorship:Principal investigator  Grant type:Collaborative (industry/university)

    グルコサミン、コンドロイチン内服による犬関節症マーカーの変化に関する研究

  • ウマ歯髄幹細胞のバンク化に向けた萌芽研究

    日本学術振興会  科学研究費補助金  萌芽研究

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    Authorship:Coinvestigator(s)  Grant type:Competitive

    Grant amount:\3500000 ( Direct Cost: \2450000 、 Indirect Cost:\1050000 )

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Academic Activities

  • 日本ウマ科学会認定試験委員会委員長

    Role(s): Planning, management, etc.

    日本ウマ科学会  2019.2

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    Type:Academic society, research group, etc. 

  • 日本獣医師会獣医学術学会誌編集委員会委員、及び産業動物臨床・家畜衛生関連部門副委員長

    Role(s): Planning, management, etc., Review, evaluation, Planning/Implementing academic research, Peer review

    日本獣医師会  2017.7

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    Type:Academic society, research group, etc. 

  • 日本獣医師会日本獣医師会獣医学術学会企画運営委員会/ 実行委員会委員

    Role(s): Planning, management, etc., Panel moderator, session chair, etc., Planning/Implementing academic research

    日本獣医師会  2015.4

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    Type:Academic society, research group, etc. 

  • 日本ウマ科学会臨床委員会委員

    Role(s): Planning, management, etc.

    日本ウマ科学会  2012.11

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    Type:Academic society, research group, etc. 

  • Journal of Equine Science編集委員会委員

    Role(s): Peer review

    日本ウマ科学会  2012.11

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    Type:Academic society, research group, etc. 

  • Journal of Veterinary Medical Science編集委員会委員

    Role(s): Peer review

    日本獣医学会  2008.10 - 2014.3

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